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Number of items: 133.
Article
Abbosh, C;
Birkbak, NJ;
Wilson, GA;
Jamal-Hanjani, M;
Constantin, T;
Salari, R;
Le Quesne, J;
... Dessimoz, C; + view all
(2017)
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
Nature
, 545
pp. 446-451.
10.1038/nature22364.
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Abbosh, C;
Venkatesan, S;
Janes, SM;
Fitzgerald, RC;
Swanton, C;
(2017)
Evolutionary dynamics in pre-invasive neoplasia.
Current Opinion in System Biology
, 2
pp. 1-8.
10.1016/j.coisb.2017.02.009.
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Angelis, A;
Montibeller, G;
Hochhauser, D;
Kanavos, P;
(2017)
Multiple criteria decision analysis in the context of health technology assessment: a simulation exercise on metastatic colorectal cancer with multiple stakeholders in the English setting.
BMC Medical Informatics and Decision Making
, 17
(1)
, Article 149. 10.1186/s12911-017-0524-3.
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Barbieri, CE;
Chinnaiyan, AM;
Lerner, SP;
Swanton, C;
Rubin, MA;
(2017)
The Emergence of Precision Urologic Oncology: A Collaborative Review on Biomarker-driven Therapeutics.
European Urology
, 71
(2)
pp. 237-246.
10.1016/j.eururo.2016.08.024.
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Barrett, JE;
Feber, A;
Herrero, J;
Tanic, M;
Wilson, GA;
Swanton, C;
Beck, S;
(2017)
Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection.
BMC Bioinformatics
, 18
, Article 354. 10.1186/s12859-017-1753-2.
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Bentham, RB;
Bryson, K;
Szabadkai, G;
(2017)
MCbiclust: a novel algorithm to discover large-scale functionally related gene sets from massive transcriptomics data collections.
Nucleic Acids Research
, 45
(15)
pp. 8712-8730.
10.1093/nar/gkx590.
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Berenjeno, IM;
Piñeiro, R;
Castillo, SD;
Pearce, W;
McGranahan, N;
Dewhurst, SM;
Meniel, V;
... Vanhaesebroeck, B; + view all
(2017)
Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.
Nature Communications
, 8
, Article 1773. 10.1038/s41467-017-02002-4.
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Bilancio, A;
Rinaldi, B;
Oliviero, MA;
Donniacuo, M;
Monti, MG;
Boscaino, A;
Marino, I;
... Migliaccio, A; + view all
(2017)
Inhibition of p110δ PI3K prevents inflammatory response and restenosis after artery injury.
Bioscience Reports
, 37
(5)
, Article BSR20171112. 10.1042/BSR20171112.
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Bilanges, B;
Alliouachene, S;
Pearce, W;
Morelli, D;
Szabadkai, G;
Chung, Y-L;
Chicanne, G;
... Vanhaesebroeck, B; + view all
(2017)
Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.
Nature Communications
, 8
, Article 1804. 10.1038/s41467-017-01969-4.
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Blakely, CM;
Watkins, TBK;
Wu, W;
Gini, B;
Chabon, JJ;
McCoach, CE;
McGranahan, N;
... Bivona, TG; + view all
(2017)
Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers.
Nature Genetics
, 49
(12)
pp. 1693-1704.
10.1038/ng.3990.
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Bosch-Vilaro, A;
Jacobs, B;
Pomella, V;
Asbagh, LA;
Kirkland, R;
Michel, J;
Singh, S;
... Tejpar, S; + view all
(2017)
Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells.
Oncotarget
, 8
(3)
pp. 4277-4288.
10.18632/oncotarget.13834.
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Butler, CR;
Hynds, RE;
Crowley, C;
Gowers, KH;
Partington, L;
Hamilton, NJ;
Carvalho, C;
... Janes, SM; + view all
(2017)
Vacuum-assisted decellularization: an accelerated protocol to generate tissue-engineered human tracheal scaffolds.
Biomaterials
, 124
pp. 95-105.
10.1016/j.biomaterials.2017.02.001.
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Calvo, E;
Moreno, V;
Flynn, M;
Holgado, E;
Olmedo, ME;
Criado, MPL;
Kahatt, C;
... Forster, M; + view all
(2017)
Antitumor activity of lurbinectedin (PM01183) and doxorubicin in relapsed small-cell lung cancer: results from a phase I study.
Annals of Oncology
, 28
(10)
pp. 2559-2566.
10.1093/annonc/mdx357.
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Caswell, DR;
Swanton, C;
(2017)
The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome.
[Review].
BMC Medicine
, 15
, Article 133. 10.1186/s12916-017-0900-y.
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Choueiri, TK;
Plimack, E;
Arkenau, H-T;
Jonasch, E;
Heng, DYC;
Powles, T;
Frigault, MM;
... Pal, SK; + view all
(2017)
Biomarker-Based Phase II Trial of Savolitinib in Patients With Advanced Papillary Renal Cell Cancer.
Journal of Clinical Oncology
, 35
(26)
pp. 2993-3001.
10.1200/JCO.2017.72.2967.
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Clements, MP;
Byrne, E;
Camarillo Guerrero, LF;
Cattin, A-L;
Zakka, L;
Ashraf, A;
Burden, JJ;
... Parrinello, S; + view all
(2017)
The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration.
Neuron
, 96
(1)
98-114.e7.
10.1016/j.neuron.2017.09.008.
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Conteduca, V;
Wetterskog, D;
Sharabiani, MTA;
Grande, E;
Fernandez-Perez, MP;
Jayaram, A;
Salvi, S;
... Spanish Oncology Genitourinary Group, .; + view all
(2017)
Androgen receptor gene status in plasma DNA associates with worse outcome on enzalutamide or abiraterone for castration-resistant prostate cancer: a multi-institution correlative biomarker study.
Annals of Oncology
, 28
(7)
pp. 1508-1516.
10.1093/annonc/mdx155.
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Corroyer-Dulmont, A;
Falzone, N;
Kersemans, V;
Thompson, J;
Allen, DP;
Able, S;
Kartsonaki, C;
... Vallis, KA; + view all
(2017)
Improved outcome of 131I-mIBG treatment through combination with
external beam radiotherapy in the SK-N-SH mouse model of
neuroblastoma.
Radiotherapy and Oncology
, 124
(3)
pp. 488-495.
10.1016/j.radonc.2017.05.002.
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Corroyer-Dulmont, A;
Falzone, N;
Kersemans, V;
Thompson, J;
Hill, M;
Danny Allen, P;
Beech, J;
... Vallis, KA; + view all
(2017)
MRI-guided radiotherapy of the SK-N-SH neuroblastoma xenograft model using a small animal radiation research platform.
British Journal of Radiology
, 90
(1069)
, Article 20160427. 10.1259/bjr.20160427.
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Crockford, A;
Zalmas, LP;
Grönroos, E;
Dewhurst, SM;
McGranahan, N;
Cuomo, ME;
Encheva, V;
... Swanton, C; + view all
(2017)
Cyclin D mediates tolerance of genome-doubling in cancers with functional p53.
Annals of Oncology
, 28
(1)
pp. 149-156.
10.1093/annonc/mdw612.
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Crolley, VE;
Gibbins, N;
(2017)
One hundred years of external approach medialisation thyroplasty.
Journal of Laryngology and Otology
, 131
(3)
pp. 202-208.
10.1017/S0022215116010033.
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Davidson, SM;
Riquelme, JA;
Takov, K;
Vicencio, JM;
Boi-Doku, C;
Khoo, V;
Doreth, C;
... Yellon, DM; + view all
(2017)
Cardioprotection mediated by exosomes is impaired in the setting of type II diabetes but can be rescued by the use of non-diabetic exosomes in vitro.
Journal of Cellular and Molecular Medicine
10.1111/jcmm.13302.
(In press).
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Diamond, JR;
Goff, B;
Forster, MD;
Bendell, JC;
Britten, CD;
Gordon, MS;
Gabra, H;
... Moore, KM; + view all
(2017)
Phase Ib study of the mitochondrial inhibitor ME-344 plus topotecan in patients with previously treated, locally advanced or metastatic small cell lung, ovarian and cervical cancers.
Investigational New Drugs
, 35
(5)
pp. 627-633.
10.1007/s10637-017-0444-1.
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Dikaios, N;
Atkinson, D;
Tudisca, C;
Purpura, P;
Forster, M;
Ahmed, H;
Beale, T;
... Punwani, S; + view all
(2017)
A comparison of Bayesian and non-linear regression methods for robust estimation of pharmacokinetics in DCE-MRI and how it affects cancer diagnosis.
Computerized Medical Imaging and Graphics
, 56
pp. 1-10.
10.1016/j.compmedimag.2017.01.003.
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Diocou, S;
Volpe, A;
Jauregui-Osoro, M;
Boudjemeline, M;
Chuamsaamarkkee, K;
Man, F;
Blower, PJ;
... Fruhwirth, GO; + view all
(2017)
[(18)F]tetrafluoroborate-PET/CT enables sensitive tumor and metastasis in vivo imaging in a sodium iodide symporter-expressing tumor model.
Scientific Reports
, 7
, Article 946. 10.1038/s41598-017-01044-4.
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Domingues, PH;
Nanduri, LSY;
Seget, K;
Venkateswaran, SV;
Agorku, D;
Vigano, C;
von Schubert, C;
... Hardt, O; + view all
(2017)
Cellular Prion Protein PrPC and Ecto-5′-Nucleotidase Are Markers of the Cellular Stress Response to Aneuploidy.
Cancer Research
, 77
(11)
pp. 2914-2926.
10.1158/0008-5472.CAN-16-3052.
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Edeline, J;
Blanc, J-F;
Campillo-Gimenez, B;
Ma, Y-T;
King, J;
Faluyi, O;
Mathurin, J;
... Meyer, T; + view all
(2017)
Prognostic scores for sorafenib-treated hepatocellular carcinoma patients: A new application for the hepatoma arterial embolisation prognostic score.
European Journal of Cancer
, 86
pp. 135-142.
10.1016/j.ejca.2017.08.036.
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Eisenblaetter, M;
Flores-Borja, F;
Lee, JJ;
Wefers, C;
Smith, H;
Hueting, R;
Cooper, MS;
... Ng, T; + view all
(2017)
Visualization of Tumor-Immune Interaction - Target-Specific Imaging of S100A8/A9 Reveals Pre-Metastatic Niche Establishment.
Theranostics
, 7
(9)
pp. 2392-2401.
10.7150/thno.17138.
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El-Khoueiry, AB;
Sangro, B;
Yau, T;
Crocenzi, TS;
Kudo, M;
Hsu, C;
Kim, T-Y;
... Melero, I; + view all
(2017)
Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial.
Lancet
, 389
(10088)
pp. 2492-2502.
10.1016/S0140-6736(17)31046-2.
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Elliott, MJ;
Butler, CR;
Varanou-Jenkins, A;
Partington, L;
Carvalho, C;
Samuel, E;
Crowley, C;
... Birchall, MA; + view all
(2017)
Tracheal Replacement Therapy with a Stem Cell-Seeded Graft: Lessons from Compassionate Use Application of a GMP-Compliant Tissue-Engineered Medicine.
Stem Cells Translational Medicine
, 6
(6)
pp. 1458-1464.
10.1002/sctm.16-0443.
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Espana-Agusti, J;
Warren, A;
Chew, SK;
Adams, DJ;
Matakidou, A;
(2017)
Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis.
Nature Communications
, 8
, Article 2026. 10.1038/s41467-017-02245.
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Ezquer, FE;
Ezquer, ME;
Vicencio, JM;
Calligaris, SD;
(2017)
Two complementary strategies to improve cell engraftment in mesenchymal stem cell-based therapy: Increasing transplanted cell resistance and increasing tissue receptivity.
Cell Adhesion & Migration
, 11
(1)
pp. 110-119.
10.1080/19336918.2016.1197480.
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Feber, A;
Dhami, P;
Dong, L;
de Winter, P;
Tan, WS;
Martínez-Fernández, M;
Paul, DS;
... Kelly, JD; + view all
(2017)
UroMark - a urinary biomarker assay for the detection of bladder cancer.
Clinical Epigenetics
, 9
, Article 8. 10.1186/s13148-016-0303-5.
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Ferolla, P;
Brizzi, MP;
Meyer, T;
Mansoor, W;
Mazieres, J;
Do Cao, C;
Léna, H;
... Baudin, E; + view all
(2017)
Efficacy and safety of long-acting pasireotide or everolimus alone or in combination in patients with advanced carcinoids of the lung and thymus (LUNA): an open-label, multicentre, randomised, phase 2 trial.
The Lancet Oncology
, 18
(12)
pp. 1652-1664.
10.1016/S1470-2045(17)30681-2.
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Flux, GD;
O'Sullivan, J;
Gaze, MN;
Prise, KM;
(2017)
Opportunities for research in molecular radiotherapy.
British Journal of Radiology
, 90
(1071)
, Article 20160921. 10.1259/bjr.20160921.
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Flynn, MJ;
Hartley, JA;
(2017)
The emerging role of anti-CD25 directed therapies as both immune modulators and targeted agents in cancer.
[Review].
British Journal of Haematology
, 179
(1)
pp. 20-35.
10.1111/bjh.14770.
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Formica, V;
Doldo, E;
Antonetti, FR;
Nardecchia, A;
Ferroni, P;
Riondino, S;
Morelli, C;
... Roselli, M; + view all
(2017)
Biological and predictive role of ERCC1 polymorphisms in cancer.
Critical Reviews in Oncology/Hematology
, 111
pp. 133-143.
10.1016/j.critrevonc.2017.01.016.
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Forster, MD;
Moschetta, M;
Uccello, M;
Kasenda, B;
Mak, G;
McClelland, A;
Boussios, S;
(2017)
Dynamics of neutrophils to lymphocyte ratio (NLR) predict outcomes of PD-1/PD-L1 blockade.
BioMed Research International
, 2017
, Article 1506824. 10.1155/2017/1506824.
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Foy, V;
Schenk, MW;
Baker, K;
Gomes, F;
Lallo, A;
Frese, KK;
Forster, M;
... Blackhall, F; + view all
(2017)
Targeting DNA damage in SCLC.
[Review].
Lung Cancer
, 114
pp. 12-22.
10.1016/j.lungcan.2017.10.006.
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George, A;
Kristeleit, R;
Rafii, S;
Michie, CO;
Bowen, R;
Michalarea, V;
van Hagen, T;
... Yap, TA; + view all
(2017)
Clinical factors of response in patients with advanced ovarian cancer participating in early phase clinical trials.
European Journal of Cancer
, 76
pp. 52-59.
10.1016/j.ejca.2017.01.020.
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Gowers, KHC;
Hynds, RE;
Thakrar, RM;
Carroll, B;
Birchall, MA;
Janes, SM;
(2017)
Optimized isolation and expansion of human airway epithelial basal cells from endobronchial biopsy samples.
Journal of Tissue Engineering and Regenerative Medicine
10.1002/term.2466.
(In press).
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Greystoke, A;
Steele, N;
Arkenau, H-T;
Blackhall, F;
Haris, NM;
Lindsay, CR;
Califano, R;
... Dean, E; + view all
(2017)
SELECT-3: a phase I study of selumetinib in combination with platinum-doublet chemotherapy for advanced NSCLC in the first-line setting.
British Journal of Cancer
, 117
pp. 938-946.
10.1038/bjc.2017.271.
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Heather, JM;
Ismail, M;
Oakes, T;
Chain, B;
(2017)
High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities.
Brief Bioinform
10.1093/bib/bbw138.
(In press).
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Helfen, A;
Roth, J;
Ng, T;
Eisenblaetter, M;
(2017)
In Vivo Imaging of Pro- and Antitumoral Cellular Components of the Tumor Microenvironment.
Journal of Nuclear Medicine
, 59
(2)
pp. 183-188.
10.2967/jnumed.117.198952.
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Hsieh, JJ;
Purdue, MP;
Signoretti, S;
Swanton, C;
Albiges, L;
Schmidinger, M;
Heng, DY;
... Ficarra, V; + view all
(2017)
Renal cell carcinoma.
Nature Reviews Disease Primers
, 3
, Article 17009. 10.1038/nrdp.2017.9.
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Hynds, RE;
Bonfanti, P;
Janes, SM;
(2017)
Regenerating human epithelia with cultured stem cells: feeder cells, organoids and beyond.
EMBO Molecular Medicine
, 2017
, Article e8213. 10.15252/emmm.201708213.
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Hynds, RE;
Janes, SM;
(2017)
Airway Basal Cell Heterogeneity and Lung Squamous Cell Carcinoma.
Cancer Prevention Research
, 10
(9)
pp. 491-493.
10.1158/1940-6207.CAPR-17-0202.
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Irshad, S;
Flores-Borja, F;
Lawler, K;
Monypenny, J;
Evans, R;
Male, V;
Gordon, P;
... Ng, T; + view all
(2017)
RORγt+ innate lymphoid cells promote lymph node metastasis of breast cancers.
Cancer Research
, 77
(5)
pp. 1083-1096.
10.1158/0008-5472.CAN-16-0598.
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Islam, MS;
Saito, JA;
Emdad, EM;
Ahmed, B;
Islam, MM;
Halim, A;
Hossen, QMM;
... Alam, M; + view all
(2017)
Comparative genomics of two jute species and insight into fibre biogenesis.
Nature Plants
, 3
(2)
, Article 16223. 10.1038/nplants.2016.223.
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Jamal-Hanjani, M;
Wilson, GA;
McGranahan, N;
Birkbak, NJ;
Watkins, TBK;
Veeriah, S;
Shafi, S;
... Swanton, C; + view all
(2017)
Tracking the Evolution of Non-Small-Cell Lung Cancer.
New England Journal of Medicine
, 376
(22)
pp. 2109-2121.
10.1056/NEJMoa1616288.
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James, ND;
de Bono, JS;
Spears, MR;
Clarke, NW;
Mason, MD;
Dearnaley, DP;
Ritchie, AWS;
... STAMPEDE Investigators; + view all
(2017)
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
The New England Journal of Medicine
, 377
pp. 338-351.
10.1056/NEJMoa1702900.
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Jones, OS;
Vassie, C;
Gilson, R;
Lechner, M;
(2017)
Until eradication, awareness.
Lancet Infectious Diseases
, 17
(4)
pp. 368-369.
10.1016/S1473-3099(17)30125-1.
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Karpathakis, A;
Dibra, H;
Pipinikas, C;
Feber, A;
Morris, T;
Francis, JM;
Oukrif, D;
... Thirlwell, C; + view all
(2017)
Progressive epigenetic dysregulation in neuroendocrine tumour liver metastasis.
Endocrine-Related Cancer
, 24
(2)
L21-L25.
10.1530/ERC-16-0419.
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King, J;
Palmer, DH;
Johnson, P;
Ross, P;
Hubner, RA;
Sumpter, K;
Darby, S;
... Meyer, T; + view all
(2017)
Sorafenib for the Treatment of Advanced Hepatocellular Cancer – a UK Audit.
Clinical Oncology
, 29
(4)
pp. 256-262.
10.1016/j.clon.2016.11.012.
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Kristeleit, R;
Davidenko, I;
Shirinkin, V;
El-Khouly, F;
Bondarenko, I;
Goodheart, MJ;
Gorbunova, V;
... Schilder, RJ; + view all
(2017)
A randomised, open-label, phase 2 study of the IDO1 inhibitor epacadostat (INCB024360) versus tamoxifen as therapy for biochemically recurrent (CA-125 relapse)-only epithelial ovarian cancer, primary peritoneal carcinoma, or fallopian tube cancer.
Gynecologic Oncology
, 146
(3)
pp. 484-490.
10.1016/j.ygyno.2017.07.005.
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Kristeleit, R;
Shapiro, GI;
Burris, HA;
Oza, AM;
LoRusso, P;
Patel, MR;
Domchek, SM;
... Shapira-Frommer, R; + view all
(2017)
A Phase I-II Study of the Oral PARP Inhibitor Rucaparib in Patients with Germline BRCA1/2-Mutated Ovarian Carcinoma or Other Solid Tumors.
Clinical Cancer Research
, 23
(15)
pp. 4095-4106.
10.1158/1078-0432.CCR-16-2796.
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Lamarca, A;
Walter, T;
Pavel, M;
Borbath, I;
Freis, P;
Nuñez, B;
Childs, A;
... Barriuso, J; + view all
(2017)
Design and Validation of the GI-NEC Score to Prognosticate Overall Survival in Patients With High-Grade Gastrointestinal Neuroendocrine Carcinomas.
Journal of the National Cancer Institute
, 109
(5)
10.1093/jnci/djw277.
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Lampada, A;
O'Prey, J;
Szabadkai, G;
Ryan, KM;
Hochhauser, D;
Salomoni, P;
(2017)
mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism.
Cell Death and Differentiation
, 24
(6)
pp. 1045-1062.
10.1038/cdd.2017.41.
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Laskaratos, F-M;
Rombouts, K;
Caplin, M;
Toumpanakis, C;
Thirlwell, C;
Mandair, D;
(2017)
Neuroendocrine tumors and fibrosis: An unsolved mystery?
Cancer
, 123
(24)
pp. 4770-4790.
10.1002/cncr.31079.
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Lawler, K;
Papouli, E;
Naceur-Lombardelli, C;
Mera, A;
Ougham, K;
Tutt, A;
Kimbung, S;
... Purushotham, A; + view all
(2017)
Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case control study.
Breast Cancer Research
, 19
, Article 113. 10.1186/s13058-017-0881-y.
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Linch, M;
Goh, G;
Hiley, C;
Shanmugabavan, Y;
McGranahan, N;
Rowan, A;
Wong, YNS;
... Swanton, C; + view all
(2017)
Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters.
Annals of Oncology
, 28
(10)
pp. 2472-2480.
10.1093/annonc/mdx355.
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Litchfield, K;
Levy, M;
Orlando, G;
Loveday, C;
Law, PJ;
Migliorini, G;
Holroyd, A;
... Turnbull, C; + view all
(2017)
Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor.
Nature Genetics
, 49
(7)
pp. 1133-1140.
10.1038/ng.3896.
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Litchfield, K;
Turajlic, S;
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Van Hemelrijck, M;
(2017)
Correction: Associations of C-Reactive Protein, Granulocytes and Granulocyte-to-Lymphocyte Ratio with Mortality from Breast Cancer in Non-Institutionalized American Women.
PLoS One
, 11
(8)
, Article e0161418. 10.1371/journal.pone.0161418.
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Proceedings paper
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Oaknin, A;
Oza, A;
Tinker, A;
Ray-Coquard, I;
Coleman, R;
O'Malley, D;
Shapira-Frommer, R;
... Kristeleit, RS; + view all
(2017)
Integrated efficacy and safety analysis of the poly(ADP-ribose) polymerase (PARP) inhibitor rucaparib in patients (pts) with high-grade ovarian carcinoma (HGOC).
In:
ECCO: 2017 European Cancer Congress. Abstract Book.
(pp. S95-S95).
Elsevier
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Conference item
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Baurain, J;
Awada, A;
Brunsvig, P;
Kristeleit, RS;
Loirat, D;
Jossang, D;
Zitvogel, L;
... Spicer, J; + view all
(2017)
A phase I dose escalation study of intra-tumoral LTX-315 as monotherapy or in combination with either ipilimumab or pembrolizumab in patients with transdermally accessible tumors (NCT01986426).
Presented at: AACR Annual Meeting 2017, Washington, D.C., USA.
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Dillon, MT;
Espinasse, A;
Ellis, S;
Mohammed, K;
Grove, LG;
McLellan, L;
Smith, SA;
... Harrington, KJ; + view all
(2017)
A Phase I dose-escalation study of ATR inhibitor monotherapy with AZD6738 in advanced solid tumors (PATRIOT Part A).
Presented at: Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC.
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Kristeleit, RS;
Lorusso, D;
Oaknin, A;
Safra, T;
Swisher, EM;
Bondarenko, IM;
Huzarski, T;
... Oza, A; + view all
(2017)
988TiP: ARIEL4: An international, randomised phase 3 study of the PARP inhibitor rucaparib vs chemotherapy for the treatment of BRCA-mutated, relapsed, high-grade ovarian cancer.
Presented at: 42nd ESMO Congress (ESMO 2017), Madrid, Spain.
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Kristeleit, RS;
Miller, R;
Sellers, L;
Brown, N;
Devlin, M;
Woo, K;
Boyd, A;
... Linch, M; + view all
(2017)
A first-in-human Phase I/II, dose escalation, pharmacokinetic study to assess safety and tolerability of VAL201 in advanced prostate cancer.
Presented at: 15th International Congress on Targeted Anticancer Therapies (TAT 2017), Paris, France.
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Miller, RE;
Devlin, M;
Brown, N;
Woo, K;
Grunewald, T;
Speirs, A;
Mitchison, M;
... Kristeleit, R; + view all
(2017)
Guidance by molecular selection improves the outcome of early phase treatment for gynecological (GYN) cancers.
Presented at: AACR Annual Meeting 2017, Washington, D.C., USA.
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Robillard, L;
Nguyen, M;
Loehr, A;
Orsulic, S;
Kristeleit, RS;
Lin, K;
Raponi, M;
... Simmons, AD; + view all
(2017)
Preclinical evaluation of the PARP inhibitor rucaparib in combination with PD-1 and PD-L1 inhibition in a syngeneic BRCA1 mutant ovarian cancer model.
Presented at: AACR Annual Meeting 2017, Washington, D.C., USA.
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Spicer, JF;
Baurain, JF;
Awada, A;
Kristeleit, RS;
Jossang, DE;
Marabelle, A;
Loirat, D;
... Brunsvig, P; + view all
(2017)
LTX-315, an oncolytic peptide, to convert immunogenically 'cold' tumors to 'hot' in patients with advanced or metastatic tumours: Results from an ongoing phase I study.
Presented at: American Society of Clinical Oncology Annual Meeting 2017, Chicago, IL, USA.
(In press).
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Poster
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Marabelle, A;
Baurain, J-F;
Awada, A;
Kristeleit, RS;
Jossang, D-E;
Jebsen, N-L;
Loirat, D;
... Spicer, J; + view all
(2017)
LTX‐315, an oncolytic peptide converts "cold" tumors to "hot" in a majority of patients with advanced cancer: results from an ongoing phase I study.
Presented at: 32nd Annual Meeting and Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2017): Part Two, National Harbor, Maryland, USA.
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Miller, R;
Devlin, M-J;
Brown, NF;
Grunewald, T;
McCormack, M;
Lockley, M;
Ledermann, JA;
... Kristeleit, RS; + view all
(2017)
Outcome of patients with advanced endometrial and cervical cancer treated in a phase 1 unit.
Presented at: 2017 Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, IL, USA.
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Thesis
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Kinna, AW;
(2017)
Improved production and purification of recombinant proteins from mammalian expression systems.
Doctoral thesis , UCL (University College London).
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