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Number of items: 84.
Article
Ariëns, RA;
Hunt, BJ;
Agbani, EO;
Ahnström, J;
Ahrends, R;
Alikhan, R;
Assinger, A;
... Zhou, J; + view all
(2022)
Illustrated State-of-the-Art Capsules of the ISTH 2022 Congress.
Research and Practice in Thrombosis and Haemostasis
, 6
(5)
, Article e12747. 10.1002/rth2.12747.
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Ascierto, Paolo A;
Agarwala, Sanjiv S;
Blank, Christian;
Caraco, Corrado;
Carvajal, Richard D;
Ernstoff, Marc S;
Ferrone, Soldano;
... Thurin, Magdalena; + view all
(2022)
Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd – 4th, 2021, Italy).
Journal of Translational Medicine
, 20
, Article 391. 10.1186/s12967-022-03592-4.
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Ashby, C;
Boyle, EM;
Bauer, MA;
Mikulasova, A;
Wardell, CP;
Williams, L;
Siegel, A;
... Morgan, GJ; + view all
(2022)
Structural variants shape the genomic landscape and clinical outcome of multiple myeloma.
Blood Cancer Journal
, 12
(5)
, Article 85. 10.1038/s41408-022-00673-x.
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Asher, Samir;
Kazantzi, Aikaterini;
Dekaj, Fatjon;
Steventon, Luke;
Khatun, Aisha;
Ainley, Louise;
McMillan, Annabel;
... Popat, Rakesh; + view all
(2022)
Under-representation of ethnic minorities in early phase clinical trials for multiple myeloma.
Haematologica
, 107
(12)
pp. 2961-2965.
10.3324/haematol.2022.281322.
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Bakhai, Ameet;
McCauley, Leah;
Stones, Liba;
Khalil, Saria;
Mehta, Jay;
Price, Nicola;
Krishnamurthy, Vinodh;
... Hughes, Derralynn; + view all
(2022)
Shining a light on an additional clinical burden: work-related digital communication survey study – COVID-19 impact on NHS staff wellbeing.
Humanities and Social Sciences Communications
, 9
, Article 414. 10.1057/s41599-022-01427-7.
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Batty, P;
Mo, AM;
Hurlbut, D;
Ishida, J;
Yates, B;
Brown, C;
Harpell, L;
... Lillicrap, D; + view all
(2022)
Long-term follow-up of liver-directed, adeno-associated vector-mediated gene therapy in the canine model of hemophilia A.
Blood
, 140
(25)
pp. 2672-2683.
10.1182/blood.2021014735.
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Beck, Michael;
Ramaswami, Uma;
Hernberg-Stahl, Elizabeth;
Hughes, Derralynn A;
Kampmann, Christoph;
Mehta, Atul B;
Nicholls, Kathleen;
... Giugliani, Roberto; + view all
(2022)
Twenty years of the Fabry Outcome Survey (FOS): insights, achievements, and lessons learned from a global patient registry.
Orphanet Journal of Rare Diseases
, 17
, Article 238. 10.1186/s13023-022-02392-9.
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Bennett, Clare;
(2022)
Loss of T cell tolerance in the skin following immunopathology is linked to failed restoration of the dermal niche by recruited macrophages.
Cell Reports
, 39
(7)
, Article 110819. 10.1016/j.celrep.2022.110819.
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Best, Jonathan G;
Arram, Liz;
Ahmed, Norin;
Balogun, Maryam;
Bennett, Kate;
Bordea, Ekaterina;
Campos, Marta G;
... OPTIMAS investigators, .; + view all
(2022)
Optimal timing of anticoagulation after acute ischemic stroke with atrial fibrillation (OPTIMAS): Protocol for a randomized controlled trial.
International Journal of Stroke
, 17
(5)
pp. 583-589.
10.1177/17474930211057722.
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Bridgewater, John;
Fletcher, Peter;
Palmer, Daniel H;
Malik, Hassan Z;
Prasad, Raj;
Mirza, Darius;
Anthony, Alan;
... BILCAP study group, .; + view all
(2022)
Long-Term Outcomes and Exploratory Analyses of the Randomized Phase III BILCAP Study.
Journal of Clinical Oncology
, 40
(18)
pp. 2048-2057.
10.1200/JCO.21.02568.
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Bridgewater, John;
Jiao, Xiaolong;
Parimi, Mounika;
Flach, Clare;
Stratford, Jeran;
Kamburov, Atanas;
Schmitz, Arndt A;
... Bazhenova, Lyudmila; + view all
(2022)
Prognosis and oncogenomic profiling of patients with tropomyosin receptor kinase fusion cancer in the 100,000 genomes project.
Cancer Treatment and Research Communications
, 33
, Article 100623. 10.1016/j.ctarc.2022.100623.
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Brimble, MA;
Cheng, PH;
Winston, SM;
Reeves, IL;
Souquette, A;
Spence, Y;
Zhou, J;
... Davidoff, AM; + view all
(2022)
Preventing packaging of translatable P5-associated DNA contaminants in recombinant AAV vector preps.
Molecular Therapy - Methods and Clinical Development
, 24
pp. 280-291.
10.1016/j.omtm.2022.01.008.
(In press).
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Bustoros, Mark;
Anand, Shankara;
Sklavenitis-Pistofidis, Romanos;
Redd, Robert;
Boyle, Eileen M;
Zhitomirsky, Benny;
Dunford, Andrew J;
... Ghobrial, Irene M; + view all
(2022)
Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes.
Nature Communications
, 13
, Article 3449. 10.1038/s41467-022-30694-w.
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Chan, WY;
Counsell, N;
de Tute, R;
De-Silva, D;
Phillips, EH;
Cavenagh, J;
Adedayo, T;
... Yong, KL; + view all
(2022)
Outcomes of relapse in patients with deferred autologous stem cell transplant after achieving at least very good partial response following bortezomib, adriamycin, dexamethasone chemotherapy for newly diagnosed multiple myeloma in the phase II PADIMAC trial.
British Journal of Haematology
, 196
(4)
e33-e37.
10.1111/bjh.17903.
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Chan, WY;
Zhu, C;
Sanchez, E;
Gupta, R;
Fielding, AK;
Khwaja, A;
Payne, EM;
(2022)
Antibody responses to SARS-CoV-2 vaccination in patients with acute myeloid leukaemia and high risk MDS on active anti-cancer therapies.
British Journal of Haematology
, 198
(3)
pp. 478-481.
10.1111/bjh.18248.
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Cheok, Kathleen PL;
Kirkwood, Amy A;
Menne, Tobias;
Tholouli, Eleni;
Chaganti, Sridhar;
Mathew, Amrith;
Uttenthal, Ben;
... Roddie, Claire; + view all
(2022)
Severe presentations and high mortality from SARS-CoV-2 in patients undergoing chimeric antigen receptor (CAR-T) therapy: a UK NCCP analysis.
Leukemia & Lymphoma
, 63
(8)
pp. 1980-1984.
10.1080/10428194.2022.2057487.
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Chowdary, P;
Nathwani, A;
(2022)
Phase 1-2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B: The authors reply.
New England Journal of Medicine
, 387
(14)
pp. 1336-1337.
10.1056/NEJMc2210918.
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Chowdary, P;
Shapiro, S;
Makris, M;
Evans, G;
Boyce, S;
Talks, K;
Dolan, G;
... Nathwani, A; + view all
(2022)
Phase 1-2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B.
The New England Journal of Medicine
, 387
(3)
pp. 237-247.
10.1056/NEJMoa2119913.
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Cooke, EA;
Smith, NAS;
Thomas, SA;
Ruston, C;
Hothi, S;
Hughes, D;
(2022)
An integrated discrete event simulation and particle swarm optimisation model for optimising efficiency of cancer diagnosis pathways.
Healthcare Analytics
, 2
, Article 100082. 10.1016/j.health.2022.100082.
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Dardis, A;
Michelakakis, H;
Rozenfeld, P;
Fumic, K;
Wagner, J;
Pavan, E;
Fuller, M;
... Aerts, J; + view all
(2022)
Patient centered guidelines for the laboratory diagnosis of Gaucher disease type 1.
Orphanet Journal of Rare Diseases
, 17
, Article 442. 10.1186/s13023-022-02573-6.
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Davies, Faith E;
Pawlyn, Charlotte;
Usmani, Saad Z;
San-Miguel, Jesus F;
Einsele, Hermann;
Boyle, Eileen M;
Corre, Jill;
... Morgan, Gareth J; + view all
(2022)
Perspectives on the Risk-Stratified Treatment of Multiple Myeloma.
Blood Cancer Discovery
, 3
(4)
pp. 273-284.
10.1158/2643-3230.BCD-21-0205.
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Day, James W;
Fox, Thomas A;
Gupta, Rajeev;
Khwaja, Asim;
Wilson, Andrew J;
Kottaridis, Panagiotis D;
(2022)
Gilteritinib monotherapy as a transplant bridging option for high risk FLT3-mutated AML with t(6;9)(p23;q34.1);DEK-NUP214 in morphological but not cytogenetic or molecular remission following standard induction chemotherapy.
Leukemia Research Reports
, 17
, Article 100291. 10.1016/j.lrr.2022.100291.
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Djebbari, F;
Rampotas, A;
Vallance, G;
Panitsas, F;
Basker, N;
Sangha, G;
Salhan, B;
... Ramasamy, K; + view all
(2022)
Efficacy of Isatuximab with Pomalidomide and Dexamethasone in Relapsed Myeloma: Results of a UK-Wide Real-World Dataset.
HemaSphere
, 6
(6)
, Article e738. 10.1097/HS9.0000000000000738.
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Doki, Yuichiro;
Ajani, Jaffer A;
Kato, Ken;
Xu, Jianming;
Wyrwicz, Lucjan;
Motoyama, Satoru;
Ogata, Takashi;
... CheckMate 648 Trial Investigators; + view all
(2022)
Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma.
New England Journal of Medicine
, 386
(5)
pp. 449-462.
10.1056/NEJMoa2111380.
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Donnellan, C;
Cohen, H;
Werring, DJ;
(2022)
Cognitive dysfunction and associated neuroimaging biomarkers in antiphospholipid syndrome: a systematic review.
Rheumatology
, 61
(1)
pp. 24-41.
10.1093/rheumatology/keab452.
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Efthymiou, M;
Lane, PJ;
Isenberg, D;
Cohen, H;
Mackie, IJ;
(2022)
Comparison of acquired activated protein C resistance, using the CAT and ST-genesia® analysers and three thrombin generation methods, in APS and SLE patients.
Journal of Clinical Medicine
, 11
(1)
, Article 69. 10.3390/jcm11010069.
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Elstein, D;
Belmatoug, N;
Deegan, P;
Göker-Alpan, Ö;
Hughes, DA;
Schwartz, IVD;
Weinreb, N;
... Zimran, A; + view all
(2022)
Development and validation of Gaucher disease type 1 (GD1)-specific patient-reported outcome measures (PROMs) for clinical monitoring and for clinical trials.
Orphanet Journal of Rare Diseases
, 17
, Article 9. 10.1186/s13023-021-02163-y.
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Farmakis, Dimitrios;
Porter, John;
Taher, Ali;
Cappellini, Maria Domenica;
Angastiniotis, Michael;
Eleftheriou, Androulla;
(2022)
2021 Thalassaemia International Federation Guidelines for the Management of Transfusion-dependent Thalassemia.
HemaSphere
, 6
(8)
, Article e732. 10.1097/HS9.0000000000000732.
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Ferrada, Marcela A;
Savic, Sinisa;
Ospina Cardona, Daniela;
Collins, Jason Charles;
Alessi, Hugh;
Gutierrez-Rodrigues, Fernanda;
Uthaya Kumar, Dinesh Babu;
... Beck, David B; + view all
(2022)
Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis.
Blood
, 140
(13)
pp. 1496-1506.
10.1182/blood.2022016985.
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Gaspar, Pedro;
Farinha, Filipa;
Sayar, Zara;
Efthymiou, Maria;
Cohen, Hannah;
Isenberg, David A;
(2022)
A one-point increase in the Damage Index for Antiphospholipid Syndrome (DIAPS) predicts mortality in thrombotic antiphospholipid syndrome.
Clinical and Experimental Rheumatology
10.55563/clinexprheumatol/0gs167.
(In press).
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Gooding, Sarah;
Ansari-Pour, Naser;
Kazeroun, Mohammad H;
Karagoz, Kubra;
Polonskaia, Ann;
Angulo Salazar, Mirian;
Fitzsimons, Evelyn;
... Thakurta, Anjan; + view all
(2022)
Loss of COP9 signalosome genes at 2q37 is associated with IMiD resistance in multiple myeloma.
Blood
, 140
(16)
pp. 1816-1821.
10.1182/blood.2022015909.
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Hagos, Yeman B;
Akarca, Ayse U;
Ramsay, Alan;
Rossi, Riccardo L;
Pomplun, Sabine;
Ngai, Victoria;
Moioli, Alessia;
... Marafioti, Teresa; + view all
(2022)
High inter-follicular spatial co-localization of CD8+FOXP3+ with CD4+CD8+ cells predicts favorable outcome in follicular lymphoma.
Hematological Oncology
10.1002/hon.3003.
(In press).
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Harrasser, Micaela;
Gohil, Satyen Harish;
Lau, Hiu;
Della Peruta, Marco;
Muczynski, Vincent;
Patel, Dominic;
Miranda, Elena;
... Nathwani, Amit Chunilal; + view all
(2022)
Inducible localized delivery of an anti-PD-1 scFv enhances anti-tumor activity of ROR1 CAR-T cells in TNBC.
Breast Cancer Research
, 24
(1)
, Article 39. 10.1186/s13058-022-01531-1.
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Hatcher, J;
Gil, E;
Storey, N;
Brown, JR;
Hartley, JC;
Breuer, J;
Lucchini, G;
... Dunn, H; + view all
(2022)
Reactivation/relapse of SARS-CoV-2 in a child following haematopoietic stem cell transplantation, confirmed by whole genome sequencing, following apparent viral clearance.
Journal of Infection
10.1016/j.jinf.2022.05.043.
(In press).
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Heide, Timon;
Househam, Jacob;
Cresswell, George D;
Spiteri, Inmaculada;
Lynn, Claire;
Mossner, Maximilian;
Kimberley, Chris;
... Sottoriva, Andrea; + view all
(2022)
The co-evolution of the genome and epigenome in colorectal cancer.
Nature
10.1038/s41586-022-05202-1.
(In press).
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Hernandez, Diana;
Danby, Robert David;
Querol, Sergio;
(2022)
Editorial: Umbilical cord blood and tissue in novel therapies and haematopoiesis research.
Frontiers in Cell and Developmental Biology
, 10
, Article 979306. 10.3389/fcell.2022.979306.
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Holm, Jeppe Sejerø;
Funt, Samuel A;
Borch, Annie;
Munk, Kamilla Kjærgaard;
Bjerregaard, Anne-Mette;
Reading, James L;
Maher, Colleen;
... Hadrup, Sine Reker; + view all
(2022)
Neoantigen-specific CD8 T cell responses in the peripheral blood following PD-L1 blockade might predict therapy outcome in metastatic urothelial carcinoma.
Nature Communications
, 13
, Article 1935. 10.1038/s41467-022-29342-0.
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Hostettler, Isabel Charlotte;
Seiffge, David;
Wong, Andrew;
Ambler, Gareth;
Wilson, Duncan;
Shakeshaft, Clare;
Banerjee, Gargi;
... Werring, David; + view all
(2022)
APOE and Cerebral Small Vessel Disease Markers in Patients With Intracerebral Hemorrhage.
Neurology
, 99
(12)
e1290-e1298.
10.1212/WNL.0000000000200851.
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Hough, R;
Lopes, A;
Patrick, P;
Russell, N;
Raj, K;
Tholouli, E;
Snowden, JA;
... Marks, D; + view all
(2022)
Primary graft failure, but not relapse, may be identified by early chimerism following double cord blood unit transplantation.
Blood Advances
, 6
(7)
pp. 2414-2426.
10.1182/bloodadvances.2021005106.
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Househam, Jacob;
Heide, Timon;
Cresswell, George D;
Spiteri, Inmaculada;
Kimberley, Chris;
Zapata, Luis;
Lynn, Claire;
... Graham, Trevor A; + view all
(2022)
Phenotypic plasticity and genetic control in colorectal cancer evolution.
Nature
10.1038/s41586-022-05311-x.
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Howell, Rowan;
Clarke, Matthew A;
Reuschl, Ann-Kathrin;
Chen, Tianyi;
Abbott-Imboden, Sean;
Singer, Mervyn;
Lowe, David M;
... Fisher, Jasmin; + view all
(2022)
Executable network of SARS-CoV-2-host interaction predicts drug combination treatments.
npj Digital Medicine
, 5
(1)
, Article 18. 10.1038/s41746-022-00561-5.
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Hughes, Derralynn A;
Aguiar, Patrício;
Lidove, Olivier;
Nicholls, Kathleen;
Nowak, Albina;
Thomas, Mark;
Torra, Roser;
... Feriozzi, Sandro; + view all
(2022)
Do clinical guidelines facilitate or impede drivers of treatment in Fabry disease?
Orphanet Journal of Rare Diseases
, 17
(1)
, Article 42. 10.1186/s13023-022-02181-4.
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Hughes, Derralynn A;
Bichet, Daniel G;
Giugliani, Roberto;
Hopkin, Robert J;
Krusinska, Eva;
Nicholls, Kathleen;
Olivotto, Iacopo;
... Wilcox, William R; + view all
(2022)
Long-term multisystemic efficacy of migalastat on Fabry-associated clinical events, including renal, cardiac and cerebrovascular outcomes.
Journal of Medical Genetics
10.1136/jmg-2022-108669.
(In press).
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Hughes, Derralynn A;
Deegan, Patrick;
Giraldo, Pilar;
Goker-Alpan, Ozlem;
Lau, Heather;
Lukina, Elena;
Revel-Vilk, Shoshana;
... Zimran, Ari; + view all
(2022)
Switching between Enzyme Replacement Therapies and Substrate Reduction Therapies in Patients with Gaucher Disease: Data from the Gaucher Outcome Survey (GOS).
Journal of Clinical Medicine
, 11
(17)
, Article 5158. 10.3390/jcm11175158.
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Khwaja, Jahanzaib;
Bomsztyk, Joshua;
Mahmood, Shameem;
Wisniowski, Brendan;
Shah, Raakhee;
Tailor, Anish;
Yong, Kwee;
... Wechalekar, Ashutosh D; + view all
(2022)
High response rates with single-agent belantamab mafodotin in relapsed systemic AL amyloidosis.
Blood Cancer Journal
, 12
(9)
, Article 128. 10.1038/s41408-022-00717-2.
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Kos, K;
Aslam, MA;
van de Ven, R;
Wellenstein, MD;
Pieters, W;
van Weverwijk, A;
Duits, DEM;
... de Visser, KE; + view all
(2022)
Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche.
Cell Reports
, 38
(9)
, Article 110447. 10.1016/j.celrep.2022.110447.
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Kuhnl, Andrea;
Roddie, Claire;
Kirkwood, Amy A;
Tholouli, Eleni;
Menne, Tobias;
Patel, Amit;
Besley, Caroline;
... McMillan, Andrew; + view all
(2022)
A national service for delivering CD19 CAR-Tin large B-cell lymphoma – The UK real-world experience.
British Journal of Haematology
, 198
(3)
pp. 492-502.
10.1111/bjh.18209.
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Leng, H;
Zhang, H;
Li, L;
Zhang, S;
Wang, Y;
Chavda, SJ;
Galas-Filipowicz, D;
... Horwood, NJ; + view all
(2022)
Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease.
Nature Communications
, 13
(1)
, Article 7868. 10.1038/s41467-022-35358-3.
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Liu, ZJ;
Deschmann, E;
Ramsey, HE;
Feldman, HA;
Psaila, B;
Cooper, N;
Vlachodimitropoulou, E;
... Sola-Visner, M; + view all
(2022)
Iron status influences the response of cord blood megakaryocyte progenitors to eltrombopag in vitro.
Blood Advances
, 6
(1)
pp. 13-27.
10.1182/bloodadvances.2021004207.
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Llombart, V;
Mansour, MR;
(2022)
Therapeutic targeting of "undruggable" MYC.
EBioMedicine
, 75
, Article 103756. 10.1016/j.ebiom.2021.103756.
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Macias, Rocio IR;
Cardinale, Vincenzo;
Kendall, Timothy J;
Avila, Matias A;
Guido, Maria;
Coulouarn, Cedric;
Braconi, Chiara;
... Carpino, Guido; + view all
(2022)
Clinical relevance of biomarkers in cholangiocarcinoma: critical revision and future directions.
Gut
10.1136/gutjnl-2022-327099.
(In press).
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Maciocia, Paul Michael;
Wawrzyniecka, Patrycja A;
Maciocia, Nicola C;
Burley, Amy;
Karpanasamy, Thaneswari;
Devereaux, Sam;
Hoekx, Malika;
... Mansour, Marc R; + view all
(2022)
Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia.
Blood
, 140
(1)
pp. 25-37.
10.1182/blood.2021013648.
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Marks, David I;
Clifton-Hadley, Laura;
Copland, Mhairi;
Hussain, Jiaull;
Menne, Tobias F;
McMillan, Andrew;
Moorman, Anthony V;
... Fielding, Adele K; + view all
(2022)
In-vivo T-cell depleted reduced-intensity conditioned allogeneic haematopoietic stem-cell transplantation for patients with acute lymphoblastic leukaemia in first remission: results from the prospective, single-arm evaluation of the UKALL14 trial.
Lancet Haematol
, 9
(4)
e276-e288.
10.1016/S2352-3026(22)00036-9.
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Marks, David I;
Kirkwood, Amy A;
Rowntree, Clare J;
Aguiar, Melanie;
Bailey, Katharine E;
Beaton, Brendan;
Cahalin, Paul;
... Fielding, Adele K; + view all
(2022)
Addition of four doses of rituximab to standard induction chemotherapy in adult patients with precursor B-cell acute lymphoblastic leukaemia (UKALL14): a phase 3, multicentre, randomised controlled trial.
Lancet Haematology
, 9
(4)
e262-e275.
10.1016/S2352-3026(22)00038-2.
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Marzolini, Maria AV;
Neill, Lorna;
O'Reilly, Maeve;
Peggs, Karl S;
Roddie, Claire;
(2022)
Lymphocyte morphology in a patient receiving CD19 chimeric antigen receptor T-cell therapy for mantle cell lymphoma.
eJHaem
, 3
(1)
pp. 245-246.
10.1002/jha2.334.
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McNamara, Mairéad G;
Bridgewater, John;
Goyal, Lipika;
Jacobs, Timothy;
Wagner, Anna D;
Goldstein, David;
Shroff, Rachna;
... Valle, Juan; + view all
(2022)
What is the gender representation in authorship in later phase systemic clinical trials in biliary tract cancer (BTC)? - a retrospective review of the published literature.
BMJ Open
, 12
(10)
, Article e064954. 10.1136/bmjopen-2022-064954.
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Michelozzi, Ilaria M;
Gomez-Castaneda, Eduardo;
Pohle, Ruben VC;
Cardoso Rodriguez, Ferran;
Sufi, Jahangir;
Puigdevall-Costa, Pau;
Subramaniyam, Meera;
... Giustacchini, Alice; + view all
(2022)
Activation priming and cytokine polyfunctionality modulate the enhanced functionality of low-affinity CD19 CAR T cells.
Blood Advances
10.1182/bloodadvances.2022008490.
(In press).
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Morgan, Huw J;
Rees, Elise;
Lanfredini, Simone;
Powell, Kate A;
Gore, Jasmine;
Gibbs, Alex;
Lovatt, Charlotte;
... Patel, Girish K; + view all
(2022)
CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis.
Journal of Clinical Investigation
, 132
(21)
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