Browse by UCL Departments and Centres
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Number of items: 80.
A
Abbosh, C;
Birkbak, NJ;
Wilson, GA;
Jamal-Hanjani, M;
Constantin, T;
Salari, R;
Le Quesne, J;
... Dessimoz, C; + view all
(2017)
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
Nature
, 545
pp. 446-451.
10.1038/nature22364.
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Amaral, AJ;
Andrade, J;
Foxall, RB;
Matoso, P;
Matos, AM;
Soares, RS;
Rocha, C;
... Sousa, AE; + view all
(2017)
miRNA profiling of human naive CD4 T cells links miR-34c-5p to cell activation and HIV replication.
The EMBO Journal
, 36
(3)
pp. 346-360.
10.15252/embj.201694335.
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Amodeo, V;
A, D;
Betts, J;
Bartesaghi, S;
Zhang, Y;
Richard-Londt, A;
Ellis, M;
... Salomoni, P; + view all
(2017)
A PML/Slit Axis Controls Physiological Cell Migration and Cancer Invasion in the CNS.
Cell Reports
, 20
(2)
pp. 411-426.
10.1016/j.celrep.2017.06.047.
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Armstrong, CA;
Moiseeva, V;
Collopy, LC;
Pearson, SR;
Ullah, TR;
Xi, ST;
Martin, J;
... Tomita, K; + view all
(2017)
Fission yeast Ccq1 is a modulator of telomerase activity.
Nucleic Acids Res
10.1093/nar/gkx1223.
(In press).
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Armstrong, CA;
Tomita, K;
(2017)
Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells.
Open Biology
, 7
(3)
, Article 160338. 10.1098/rsob.160338.
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B
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Barrett, JE;
Feber, A;
Herrero, J;
Tanic, M;
Wilson, GA;
Swanton, C;
Beck, S;
(2017)
Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection.
BMC Bioinformatics
, 18
, Article 354. 10.1186/s12859-017-1753-2.
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Barrington, C;
Finn, R;
Hadjur, S;
(2017)
Cohesin biology meets the loop extrusion model.
Chromosome Research
, 25
(1)
pp. 51-60.
10.1007/s10577-017-9550-3.
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Barrington, C;
Pezic, D;
Hadjur, S;
(2017)
Chromosome structure dynamics during the cell cycle: a structure to fit every phase.
The EMBO Journal
, 36
(17)
, Article e201798014. 10.15252/embj.201798014.
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Bernatsky, S;
Velásquez García, HA;
Spinelli, JJ;
Gaffney, P;
Smedby, KE;
Ramsey-Goldman, R;
Wang, SS;
... Clarke, AE; + view all
(2017)
Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma.
Lupus Sci Med
, 4
(1)
, Article e000187. 10.1136/lupus-2016-000187.
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Boege, Y;
Malehmir, M;
Healy, ME;
Bettermann, K;
Lorentzen, A;
Vucur, M;
Ahuja, AK;
... Weber, A; + view all
(2017)
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development.
Cancer Cell
, 32
(3)
pp. 342-359.
10.1016/j.ccell.2017.08.010.
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Boto, C;
Quartin, E;
Cai, Y;
Martin-Lorenzo, A;
Garcia Cenador, MB;
Pinto, S;
Gupta, R;
... Ferreira, L; + view all
(2017)
Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation.
Nature Communications
, 8
, Article 15204. 10.1038/ncomms15204.
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Breeze, Charles E;
(2017)
Epigenetics of complex traits and diseases.
Doctoral thesis (Ph.D), UCL (University College London).
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Brooks, L;
Viardot, A;
Tsakmaki, A;
Stolarczyk, E;
Howard, JK;
Cani, PD;
Everard, A;
... Bewick, GA; + view all
(2017)
Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety.
Molecular Metabolism
, 6
(1)
pp. 48-60.
10.1016/j.molmet.2016.10.011.
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Brooks, LJ;
Parrinello, S;
(2017)
Vascular regulation of glioma stem-like cells: a balancing act.
Current Opinion in Neurobiology
, 47
pp. 8-15.
10.1016/j.conb.2017.06.008.
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Budin-Ljøsne, I;
Teare, HJ;
Kaye, J;
Beck, S;
Bentzen, HB;
Caenazzo, L;
Collett, C;
... Mascalzoni, D; + view all
(2017)
Dynamic Consent: a potential solution to some of the challenges of modern biomedical research.
BMC Medical Ethics
, 18
, Article 4. 10.1186/s12910-016-0162-9.
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Butcher, LM;
Beck, S;
(2017)
Nano-MeDIP-seq Methylome Analysis Using Low DNA Concentrations.
Methods in Molecular Biology: Population Epigenetics
, 1589
pp. 115-138.
10.1007/7651_2015_259.
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C
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Cheung, WA;
Shao, X;
Morin, A;
Siroux, V;
Kwan, T;
Ge, B;
Aissi, D;
... Grundberg, E; + view all
(2017)
Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome.
Genome Biology
, 18
, Article 50. 10.1186/s13059-017-1173-7.
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Clements, MP;
Byrne, E;
Camarillo Guerrero, LF;
Cattin, A-L;
Zakka, L;
Ashraf, A;
Burden, JJ;
... Parrinello, S; + view all
(2017)
The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration.
Neuron
, 96
(1)
98-114.e7.
10.1016/j.neuron.2017.09.008.
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D
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de la Rosa, R;
Steinmaus, C;
Akers, NK;
Conde, L;
Ferreccio, C;
Kalman, D;
Zhang, KR;
... Smith, MT; + view all
(2017)
Associations between arsenic (+3 oxidation state) methyltransferase (AS3MT) and N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) polymorphisms, arsenic metabolism, and cancer risk in a chilean population.
Environmental and Molecular Mutagenesis
, 58
(6)
pp. 411-422.
10.1002/em.22104.
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E
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Ecker, S;
Beck, S;
(2017)
Epigenetic variation taking center stage in immunological research.
Epigenomics
, 9
(4)
pp. 375-378.
10.2217/epi-2017-0006.
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Ecker, S;
Chen, L;
Pancaldi, V;
Bagger, FO;
Fernández, JM;
Carrillo de Santa Pau, E;
Juan, D;
... Paul, DS; + view all
(2017)
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.
Genome Biology
, 18
, Article 18. 10.1186/s13059-017-1156-8.
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F
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Fanale, D;
Amodeo, V;
Caruso, S;
(2017)
The Interplay between Metabolism, PPAR Signaling Pathway, and Cancer.
PPAR Research
, 2017
, Article 1830626. 10.1155/2017/1830626.
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Feber, A;
Dhami, P;
Dong, L;
de Winter, P;
Tan, WS;
Martínez-Fernández, M;
Paul, DS;
... Kelly, JD; + view all
(2017)
UroMark - a urinary biomarker assay for the detection of bladder cancer.
Clinical Epigenetics
, 9
, Article 8. 10.1186/s13148-016-0303-5.
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G
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Galleu, A;
Riffo-Vasquez, Y;
Trento, C;
Lomas, C;
Dolcetti, L;
Cheung, TS;
von Bonin, M;
... Dazzi, F; + view all
(2017)
Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation.
Science Translational Medicine
, 9
(416)
, Article eaam7828. 10.1126/scitranslmed.aam7828.
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Giampazolias, E;
Zunino, B;
Dhayade, S;
Bock, F;
Cloix, C;
Cao, K;
Roca, A;
... Tait, SWG; + view all
(2017)
Mitochondrial permeabilization engages NF-kappa B-dependent anti-tumour activity under caspase deficiency.
Nature Cell Biology
, 19
(9)
pp. 1116-1129.
10.1038/ncb3596.
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Godfrey, M;
Touati, SA;
Kataria, M;
Jones, A;
Snijders, AP;
Uhlmann, F;
(2017)
PP2A(Cdc55) Phosphatase Imposes Ordered Cell- Cycle Phosphorylation by Opposing Threonine Phosphorylation.
Molecular Cell
, 65
(3)
393-402.e3.
10.1016/j.molcel.2016.12.018.
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Guibentif, C;
Ronn, RE;
Boiers, C;
Lang, S;
Saxena, S;
Soneji, S;
Enver, T;
... Woods, N-B; + view all
(2017)
Single-Cell Analysis Identifies Distinct Stages of Human Endothelial-to-Hematopoietic Transition.
Cell Reports
, 19
(1)
pp. 10-19.
10.1016/j.celrep.2017.03.023.
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H
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Hartwig, T;
Montinaro, A;
von Karstedt, S;
Sevko, A;
Surinova, S;
Chakravarthy, A;
Taraborrelli, L;
... Walczak, H; + view all
(2017)
The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2.
Molecular Cell
, 65
(4)
pp. 730-742.
10.1016/j.molcel.2017.01.021.
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J
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Jamal-Hanjani, M;
Wilson, GA;
McGranahan, N;
Birkbak, NJ;
Watkins, TBK;
Veeriah, S;
Shafi, S;
... Swanton, C; + view all
(2017)
Tracking the Evolution of Non-Small-Cell Lung Cancer.
New England Journal of Medicine
, 376
(22)
pp. 2109-2121.
10.1056/NEJMoa1616288.
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K
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Karpathakis, A;
Dibra, H;
Pipinikas, C;
Feber, A;
Morris, T;
Francis, JM;
Oukrif, D;
... Thirlwell, C; + view all
(2017)
Progressive epigenetic dysregulation in neuroendocrine tumour liver metastasis.
Endocrine-Related Cancer
, 24
(2)
L21-L25.
10.1530/ERC-16-0419.
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Kataria, M;
(2017)
How does Cdc14 order exit from mitosis?
Doctoral thesis , UCL (University College London).
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Kato, I;
Nishinaka, Y;
Nakamura, M;
Akarca, AU;
Niwa, A;
Ozawa, H;
Yoshida, K;
... Enver, T; + view all
(2017)
Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA.
Blood
, 129
(23)
pp. 3126-3129.
10.1182/blood-2016-06-721712.
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Kling, T;
Wenger, A;
Beck, S;
Caren, H;
(2017)
Validation of the Methylation EPIC BeadChip for fresh-frozen and formalin-fixed paraffinembedded tumours.
Clinical Epigenetics
, 9
, Article 33. 10.1186/s13148-017-0333-7.
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Kuderna, LFK;
Tomlinson, C;
Hillier, LW;
Tran, A;
Fiddes, I;
Armstrong, J;
Laayouni, H;
... Marques-Bonet, T; + view all
(2017)
A 3-way hybrid approach to generate a new high quality chimpanzee reference genome (Pan_tro_3.0).
GigaScience
, 6
(11)
pp. 1-6.
10.1093/gigascience/gix098.
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Kupka, S;
(2017)
Regulation of theTNFR1-signalling complex by LUBAC and associated deubiquitinases.
Doctoral thesis , UCL (University College London).
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L
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La Paglia, L;
Listi, A;
Caruso, S;
Amodeo, V;
Passiglia, F;
Bazan, V;
Fanale, D;
(2017)
Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway.
PPAR Research
, 2017
, Article 8187235. 10.1155/2017/8187235.
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Lafont, E;
Kantari-Mimoun, C;
Draber, P;
De Miguel, D;
Hartwig, T;
Reichert, M;
Kupka, S;
... Walczak, H; + view all
(2017)
The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.
EMBO Journal
, 36
(6)
, Article e201695699. 10.15252/embj.201695699.
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Law, PJ;
Berndt, SI;
Speedy, HE;
Camp, NJ;
Sava, GP;
Skibola, CF;
Holroyd, A;
... Slager, S; + view all
(2017)
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.
Nature Communications
, 8
, Article 14175. 10.1038/ncomms14175.
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Linch, M;
Goh, G;
Hiley, C;
Shanmugabavan, Y;
McGranahan, N;
Rowan, A;
Wong, YNS;
... Swanton, C; + view all
(2017)
Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters.
Annals of Oncology
, 28
(10)
pp. 2472-2480.
10.1093/annonc/mdx355.
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Liu, TH;
Tang, YJ;
Huang, Y;
Wang, L;
Guo, XL;
Mi, JQ;
Liu, LG;
... Hong, DL; + view all
(2017)
Expression of the fetal hematopoiesis regulator FEV indicates leukemias of prenatal origin.
Leukemia
, 31
(5)
pp. 1079-1086.
10.1038/leu.2016.313.
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M
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Marelli, S;
(2017)
Characterization of molecular pathways regulating the latent-to-lytic switch in γ-herpesviruses.
Doctoral thesis , UCL (University College London).
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McGranahan, N;
Rosenthal, R;
Hiley, CT;
Rowan, AJ;
Watkins, TBK;
Wilson, GA;
Birkbak, NJ;
... Swanton, C; + view all
(2017)
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.
Cell
10.1016/j.cell.2017.10.001.
(In press).
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Migueles, RP;
Shaw, L;
Rodrigues, NP;
May, G;
Henseleit, K;
Anderson, KGV;
Goker, H;
... Enver, T; + view all
(2017)
Transcriptional regulation of Hhex in hematopoiesis and hematopoietic stem cell ontogeny.
Developmental Biology
, 424
(2)
pp. 236-245.
10.1016/j.ydbio.2016.12.021.
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Mladenovic, J;
Susnjar, S;
Tanic, M;
Jankovic, R;
Karadzic, K;
Gavrilovic, D;
Stojanovic, S;
(2017)
Tumor response and patient outcome after preoperative radiotherapy in locally advanced non-inflammatory breast cancer patients.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology
, 22
(2)
pp. 325-333.
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Moiseeva, V;
Amelina, H;
Collopy, LC;
Armstrong, CA;
Pearson, SR;
Tomita, K;
(2017)
The telomere bouquet facilitates meiotic prophase progression and exit in fission yeast.
Cell Discovery
, 3
, Article 17041. 10.1038/celldisc.2017.41.
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Moniz, LS;
Surinova, S;
Ghazaly, E;
Velasco, LG;
Haider, S;
Rodriguez-Prados, JC;
Berenjeno, IM;
... Vanhaesebroeck, B; + view all
(2017)
Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate.
Scientific Reports
, 7
(39985)
10.1038/srep39985.
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Mughal, S;
Moghul, I;
Yu, J;
Clark, T;
Gregory, DS;
Pontikos, N;
(2017)
Pheno4J: a gene to phenotype graph database.
Bioinformatics
, 33
(20)
pp. 3317-3319.
10.1093/bioinformatics/btx397.
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O
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Oka, A;
Asano, Y;
Hasegawa, M;
Fujimoto, M;
Ishikawa, O;
Kuwana, M;
Kawaguchi, Y;
... Ihn, H; + view all
(2017)
RXRB is a MHC-encoded susceptibility gene associated with anti-topoisomerase I antibody-positive systemic sclerosis.
Journal of Investigative Dermatology
, 137
(9)
pp. 1878-1886.
10.1016/j.jid.2017.04.028.
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P
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Pan, S;
Lai, H;
Shen, Y;
Breeze, C;
Beck, S;
Hong, T;
Wang, C;
(2017)
DNA methylome analysis reveals distinct epigenetic patterns of ascending aortic dissection and bicuspid aortic valve.
Cardiovascular Research
, 113
(6)
pp. 692-704.
10.1093/cvr/cvx050.
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Pathania, M;
De Jay, N;
Maestro, N;
Harutyunyan, AS;
Nitarska, J;
Pahlavan, P;
Henderson, S;
... Salomoni, P; + view all
(2017)
H3.3(K27M) Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas.
Cancer Cell
, 32
(5)
, Article e9. 10.1016/j.ccell.2017.09.014.
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Pezic, D;
Weeks, SL;
Hadjur, S;
(2017)
More to cohesin than meets the eye: complex diversity for fine-tuning of function.
Current Opinion in Genetics & Development
, 43
pp. 93-100.
10.1016/j.gde.2017.01.004.
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Pontikos, N;
Yu, J;
Moghul, I;
Withington, L;
Blanco-Kelly, F;
Vulliamy, T;
Wong, TL;
... Plagnol, V; + view all
(2017)
Phenopolis: an open platform for harmonization and analysis of genetic and phenotypic data.
Bioinformatics
, 33
(15)
pp. 2421-2423.
10.1093/bioinformatics/btx147.
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Provenzano, L;
Ryan, Y;
Hilton, DA;
Lyons-Rimmer, J;
Dave, F;
Maze, EA;
Adams, CL;
... Hanemann, CO; + view all
(2017)
Cellular prion protein (PrPC) in the development of Merlin-deficient tumours.
Oncogene
, 36
pp. 6132-6142.
10.1038/onc.2017.200.
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R
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Reichert, Matthias;
(2017)
Regulation of TNFR1 signalling by LUBAC-dependent and -associated proteins.
Doctoral thesis , UCL (University College London).
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Rosenthal, R;
McGranahan, N;
Herrero, J;
Swanton, C;
(2017)
Deciphering Genetic Intratumor Heterogeneity and Its Impact on Cancer Evolution.
Annual Review of Cancer Biology
, 1
pp. 223-240.
10.1146/annurev-cancerbio-042516-011348.
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S
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Schütte, M;
Risch, T;
Abdavi-Azar, N;
Boehnke, K;
Schumacher, D;
Keil, M;
Yildiriman, R;
... Yaspo, ML; + view all
(2017)
Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Nature Communications
, 8
, Article 14262. 10.1038/ncomms14262.
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Serbanovic-Canic, J;
de Luca, A;
Warboys, C;
Ferreira, PF;
Luong, LA;
Hsiao, S;
Gauci, I;
... Evans, PC; + view all
(2017)
Zebrafish Model for Functional Screening of Flow-Responsive Genes.
Arteriosclerosis, Thrombosis and Vascular Biology
, 37
(1)
pp. 130-143.
10.1161/ATVBAHA.116.308502.
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Shimizu, Y;
(2017)
Molecular and functional characterisation of linear ubiquitination in the liver.
Doctoral thesis , UCL (University College London).
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Shimizu, Y;
Peltzer, N;
Sevko, A;
Lafont, E;
Sarr, A;
Draberova, H;
Walczak, H;
(2017)
The linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis.
Hepatology
, 65
(6)
pp. 1963-1978.
10.1002/hep.29074.
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Singh, A;
Mishra, A;
Khosravi, A;
Khandelwal, G;
Jayaram, B;
(2017)
Physico-chemical fingerprinting of RNA genes.
Nucleic Acids Research
, 45
(7)
, Article e47. 10.1093/nar/gkw1236.
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Singh, HD;
Otano, I;
Rombouts, K;
Singh, KP;
Peppa, D;
Gill, US;
Bottcher, K;
... Maini, MK; + view all
(2017)
TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis.
Scientific Reports
, 7
, Article 5514. 10.1038/s41598-017-05845-5.
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Skalska, L;
Beltran-Nebot, M;
Ule, J;
Jenner, RG;
(2017)
Regulatory feedback from nascent RNA to chromatin and transcription.
Nature Reviews Molecular Cell Biology
, 18
(5)
pp. 331-337.
10.1038/nrm.2017.12.
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Soderquest, K;
Hertweck, A;
Giambartolomei, C;
Henderson, S;
Mohamed, R;
Goldberg, R;
Perucha, E;
... Lord, GM; + view all
(2017)
Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease.
PLOS GENETICS
, 13
(2)
10.1371/journal.pgen.1006587.
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Stathopoulou, A;
Chhetri, JB;
Ambrose, JC;
Estève, P-O;
Ji, L;
Erdjument-Bromage, H;
Zhang, G;
... Ooi, SKT; + view all
(2017)
A novel requirement for DROSHA in maintenance of mammalian CG methylation.
Nucleic Acids Research
, 45
(16)
pp. 9398-9412.
10.1093/nar/gkx695.
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Stathopoulou, A;
Chhetri, JB;
Ambrose, JC;
Estève, P-O;
Ji, L;
Erdjument-Bromage, H;
Zhang, G;
... Ooi, SKT; + view all
(2017)
A novel requirement for DROSHA in maintenance of mammalian CG methylation.
[Corrigendum].
Nucleic Acids Research
, 45
(16)
p. 9810.
10.1093/nar/gkx736.
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Stockwell, SR;
Mittnacht, S;
(2017)
High-Content Imaging and RNAi Screens for Investigating Kinase Network Plasticity.
Kinase Signaling Networks
, 1636
pp. 133-161.
10.1007/978-1-4939-7154-1_10.
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Stricker, SH;
Koferle, A;
Beck, S;
(2017)
From profiles to function in epigenomics.
[Review].
Nature Reviews Genetics
, 18
(1)
pp. 51-66.
10.1038/nrg.2016.138.
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Szlosarek, PW;
Steele, JP;
Nolan, L;
Gilligan, D;
Taylor, P;
Spicer, J;
Lind, M;
... Hackshaw, A; + view all
(2017)
Arginine Deprivation With Pegylated Arginine Deiminase in Patients With Argininosuccinate Synthetase 1-Deficient Malignant Pleural Mesothelioma A Randomized Clinical Trial.
JAMA Oncology
, 3
(1)
pp. 58-66.
10.1001/jamaoncol.2016.3049.
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T
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Tanic, M;
Beck, S;
(2017)
Cell-free DNA: Treasure trove for cancer medicine.
Nature Materials
, 16
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