Browse by UCL people
Group by: Type | Date
Number of items: 93.
Article
Abbosh, C;
Birkbak, NJ;
Wilson, GA;
Jamal-Hanjani, M;
Constantin, T;
Salari, R;
Le Quesne, J;
... Dessimoz, C; + view all
(2017)
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
Nature
, 545
pp. 446-451.
10.1038/nature22364.
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AbdulJabbar, K;
Raza, SEA;
Rosenthal, R;
Jamal-Hanjani, M;
Veeriah, S;
Akarca, A;
Lund, T;
... Yuan, Y; + view all
(2020)
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma.
Nature Medicine
, 26
pp. 1054-1062.
10.1038/s41591-020-0900-x.
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Agliardi, G;
Liuzzi, AR;
Hotblack, A;
De Feo, D;
Núñez, N;
Stowe, CL;
Friebel, E;
... Becher, B; + view all
(2021)
Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma.
Nature Communications
, 12
, Article 444. 10.1038/s41467-020-20599-x.
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Al Bakir, Maise;
Huebner, Ariana;
Martínez-Ruiz, Carlos;
Grigoriadis, Kristiana;
Watkins, Thomas BK;
Pich, Oriol;
Moore, David A;
... Swanton, Charles; + view all
(2023)
The evolution of non-small cell lung cancer metastases in TRACERx.
Nature
10.1038/s41586-023-05729-x.
(In press).
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Alrasheed, N;
Lee, L;
Ghorani, E;
Henry, JY;
Conde, L;
Chin, M;
Galas-Filipowicz, D;
... Yong, KL; + view all
(2020)
Marrow-Infiltrating Regulatory T Cells Correlate with the Presence of Dysfunctional CD4⁺PD-1⁺ Cells and Inferior Survival in Patients with Newly Diagnosed Multiple Myeloma.
Clinical Cancer Research
, 26
(13)
pp. 3443-3454.
10.1158/1078-0432.CCR-19-1714.
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Ascierto, Paolo A;
Agarwala, Sanjiv S;
Blank, Christian;
Caraco, Corrado;
Carvajal, Richard D;
Ernstoff, Marc S;
Ferrone, Soldano;
... Thurin, Magdalena; + view all
(2022)
Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd – 4th, 2021, Italy).
Journal of Translational Medicine
, 20
, Article 391. 10.1186/s12967-022-03592-4.
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Ascierto, PA;
Bifulco, C;
Galon, J;
Garbe, C;
Khleif, SN;
McQuade, J;
Odunsi, K;
... Puzanov, I; + view all
(2020)
The Great Debate at 'Immunotherapy Bridge', Naples, December 5, 2019.
Journal for ImmunoTherapy of Cancer
, 8
(2)
, Article e000921. 10.1136/jitc-2020-000921.
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Ascierto, PA;
Blank, C;
Dummer, R;
Ernstoff, MS;
Ferrone, S;
Fox, BA;
Gajewski, TF;
... Thurin, M; + view all
(2021)
Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 3rd-5th, 2020, Italy).
Journal of Translational Medicine
, 19
, Article 278. 10.1186/s12967-021-02951-x.
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Au, L;
Hatipoglu, E;
Robert de Massy, M;
Litchfield, K;
Beattie, G;
Rowan, A;
Schnidrig, D;
... TRACERx Renal Consortium; + view all
(2021)
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.
Cancer Cell
, 39
pp. 1497-1518.
10.1016/j.ccell.2021.10.001.
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Bentham, R;
Litchfield, K;
Watkins, TBK;
Lim, EL;
Rosenthal, R;
Martinez-Ruiz, C;
Hiley, CT;
... McGranahan, N; + view all
(2021)
Using DNA sequencing data to quantify T cell fraction and therapy response.
Nature
, 597
pp. 555-560.
10.1038/s41586-021-03894-5.
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Bentzen, AK;
Marquard, AM;
Lyngaa, R;
Saini, SK;
Ramskov, S;
Donia, M;
Such, L;
... Hadrup, SR; + view all
(2016)
Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes.
Nature Biotechnology
, 34
(10)
pp. 1037-1045.
10.1038/nbt.3662.
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Berlato, C;
Khan, MN;
Schioppa, T;
Thompson, R;
Maniati, E;
Montfort, A;
Jangani, M;
... Balkwill, FR; + view all
(2017)
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
Journal of Clinical Investigation
, 127
(3)
pp. 801-813.
10.1172/JCI82976.
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Biswas, D;
Birkbak, NJ;
Rosenthal, R;
Hiley, CT;
Lim, EL;
Papp, K;
Boeing, S;
... TRACERx Consortium; + view all
(2019)
A clonal expression biomarker associates with lung cancer mortality.
Nature Medicine
, 25
pp. 1540-1548.
10.1038/s41591-019-0595-z.
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Boire, A;
Coffelt, SB;
Quezada, SA;
Vander Heiden, MG;
Weeraratna, AT;
(2019)
Tumour Dormancy and Reawakening: Opportunities and Challenges.
Trends in Cancer
, 5
(12)
pp. 762-765.
10.1016/j.trecan.2019.10.010.
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Carter, TJ;
Agliardi, G;
Lin, F-Y;
Ellis, M;
Jones, C;
Robson, M;
Richard-Londt, A;
... Chester, K; + view all
(2021)
Potential of Magnetic Hyperthermia to Stimulate Localized Immune Activation.
Small
, Article e2005241. 10.1002/smll.202005241.
(In press).
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Castillo, Simon P;
Galvez-Cancino, Felipe;
Liu, Jiali;
Pollard, Steven M;
Quezada, Sergio A;
Yuan, Yinyin;
(2023)
The tumour ecology of quiescence: Niches across scales of complexity.
Seminars in Cancer Biology
, 92
pp. 139-149.
10.1016/j.semcancer.2023.04.004.
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Chakravarthy, A;
Furness, A;
Joshi, K;
Ghorani, E;
Ford, K;
Ward, MJ;
King, EV;
... Fenton, TR; + view all
(2018)
Author Correction: Pan-cancer deconvolution of tumour composition using DNA methylation.
[Corrigendum].
Nature Communications
, 9
, Article 4642. 10.1038/s41467-018-07155-4.
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Chakravarthy, A;
Furness, A;
Joshi, K;
Ghorani, E;
Ford, K;
Ward, MJ;
King, EV;
... Fenton, TR; + view all
(2018)
Pan-cancer deconvolution of tumour composition using DNA methylation.
Nature Communications
, 9
, Article 3220. 10.1038/s41467-018-05570-1.
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Chan, TA;
Yarchoan, M;
Jaffee, E;
Swanton, C;
Quezada, SA;
Stenzinger, A;
Peters, S;
(2019)
Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic.
Annals of Oncology
, 30
(1)
pp. 44-56.
10.1093/annonc/mdy495.
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Chemi, F;
Rothwell, DG;
McGranahan, N;
Gulati, S;
Abbosh, C;
Pearce, SP;
Zhou, C;
... TRACERx Consortium, .; + view all
(2019)
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.
Nature Medicine
, 25
pp. 1534-1539.
10.1038/s41591-019-0593-1.
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Dodagatta-Marri, E;
Meyer, DS;
Reeves, MQ;
Paniagua, R;
To, MD;
Binnewies, M;
Broz, ML;
... Akhurst, RJ; + view all
(2019)
α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas.
Journal for ImmunoTherapy of Cancer
, 7
, Article 62. 10.1186/s40425-018-0493-9.
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Enfield, Katey SS;
Colliver, Emma;
Lee, Claudia SY;
Magness, Alastair;
Moore, David A;
Sivakumar, Monica;
Grigoriadis, Kristiana;
... Angelova, Mihaela; + view all
(2024)
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer.
Cancer Discovery
, 14
(1)
pp. 1-30.
10.1158/2159-8290.CD-23-1380.
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Fanelli, G;
Romano, M;
Nova-Lamperti, E;
Werner Sunderland, M;
Nerviani, A;
Scottà, C;
Bombardieri, M;
... Becker, PD; + view all
(2021)
PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype.
PLoS Biology
, 19
(4)
, Article e3001199. 10.1371/journal.pbio.3001199.
(In press).
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Frankell, Alexander M;
Dietzen, Michelle;
Al Bakir, Maise;
Lim, Emilia L;
Karasaki, Takahiro;
Ward, Sophia;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2024)
The evolution of lung cancer and impact of subclonal selection in TRACERx (vol 616, pg 525, 2023).
[Corrigendum].
Nature
, 631
, Article E15. 10.1038/s41586-024-07738-w.
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Frankell, AM;
Dietzen, M;
Al Bakir, M;
Lim, EL;
Karasaki, T;
Ward, S;
Veeriah, S;
... Gilbert, K; + view all
(2023)
The evolution of lung cancer and impact of subclonal selection in TRACERx.
Nature
, 616
pp. 525-533.
10.1038/s41586-023-05783-5.
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Fu, X;
Zhao, Y;
Lopez, JI;
Rowan, A;
Au, L;
Fendler, A;
Hazell, S;
... Bates, PA; + view all
(2021)
Spatial patterns of tumour growth impact clonal diversification in a computational model and the TRACERx Renal study.
Nature Ecology & Evolution
10.1038/s41559-021-01586-x.
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Furness, AJ;
Quezada, SA;
Peggs, KS;
(2016)
Neoantigen heterogeneity: a key driver of immune response and sensitivity to immune checkpoint blockade?
[Editorial comment].
Immunotherapy
, 8
(7)
pp. 763-766.
10.2217/imt-2016-0064.
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Galvez-Cancino, Felipe;
Simpson, Alexander P;
Costoya, Cristobal;
Matos, Ignacio;
Qian, Danwen;
Peggs, Karl S;
Litchfield, Kevin;
(2023)
Fcγ receptors and immunomodulatory antibodies in cancer.
Nature Reviews Cancer
, 24
(1)
pp. 51-71.
10.1038/s41568-023-00637-8.
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Gangoso, E;
Southgate, B;
Bradley, L;
Rus, S;
Galvez-Cancino, F;
McGivern, N;
Güç, E;
... Pollard, SM; + view all
(2021)
Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.
Cell
10.1016/j.cell.2021.03.023.
(In press).
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Ghorani, Ehsan;
Swanton, Charles;
Quezada, Sergio A;
(2023)
Cancer cell-intrinsic mechanisms driving acquired immune tolerance.
Immunity
, 56
(10)
pp. 2270-2295.
10.1016/j.immuni.2023.09.004.
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Ghorani, E;
Kaur, B;
Fisher, RA;
Short, D;
Joneborg, U;
Carlson, JW;
Akarca, A;
... Seckl, MJ; + view all
(2017)
Pembrolizumab is effective for drugresistant gestational trophoblastic neoplasia.
The Lancet
, 390
(10110)
pp. 2343-2345.
10.1016/S0140-6736(17)32894-5.
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Ghorani, E;
Quezada, SA;
(2018)
Chromatin regulation and immune escape.
Science
, 359
(6377)
pp. 745-746.
10.1126/science.aat0383.
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Ghorani, E;
Reading, JL;
Henry, JY;
Massy, MRD;
Rosenthal, R;
Turati, V;
Joshi, K;
... Quezada, SA; + view all
(2020)
The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
Nature Cancer
, 1
(5)
pp. 546-561.
10.1038/s43018-020-0066-y.
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Ghorani, E;
Rosenthal, R;
McGranahan, N;
Reading, JL;
Lynch, M;
Peggs, KS;
Swanton, C;
(2018)
Differential binding affinity of mutated peptides for MHC class I is a predictor of survival in advanced lung cancer and melanoma.
Annals of Oncology
, 29
(1)
pp. 271-279.
10.1093/annonc/mdx687.
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Gregucci, Fabiana;
Spada, Sheila;
Barcellos-Hoff, Mary Helen;
Bhardwaj, Nina;
Hak, Charleen Chan Wah;
Fiorentino, Alba;
Guha, Chandan;
... Formenti, Silvia C; + view all
(2023)
Updates on radiotherapy-immunotherapy combinations: Proceedings of 6(th) annual ImmunoRad conference.
OncoImmunology
, 12
(1)
, Article 2222560. 10.1080/2162402X.2023.2222560.
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Hagos, Yeman B;
Akarca, Ayse U;
Ramsay, Alan;
Rossi, Riccardo L;
Pomplun, Sabine;
Ngai, Victoria;
Moioli, Alessia;
... Marafioti, Teresa; + view all
(2022)
High inter-follicular spatial co-localization of CD8+FOXP3+ with CD4+CD8+ cells predicts favorable outcome in follicular lymphoma.
Hematological Oncology
10.1002/hon.3003.
(In press).
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Hartwig, T;
Montinaro, A;
von Karstedt, S;
Sevko, A;
Surinova, S;
Chakravarthy, A;
Taraborrelli, L;
... Walczak, H; + view all
(2017)
The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2.
Molecular Cell
, 65
(4)
pp. 730-742.
10.1016/j.molcel.2017.01.021.
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Hynds, Robert E;
Huebner, Ariana;
Pearce, David R;
Hil, Mark S;
Akarca, Ayse U;
Moore, David A;
Ward, Sophia;
... Swanton, Charles; + view all
(2024)
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models.
Nature Communications
, 15
, Article 4653. 10.1038/s41467-024-47547-3.
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Hynds, RE;
Ben Aissa, A;
Gowers, KHC;
Watkins, TBK;
Bosshard-Carter, L;
Rowan, AJ;
Veeriah, S;
... Janes, SM; + view all
(2018)
Expansion of airway basal epithelial cells from primary human non-small cell lung cancer tumors.
International Journal of Cancer
, 143
(1)
pp. 160-166.
10.1002/ijc.31383.
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Irshad, S;
Flores-Borja, F;
Lawler, K;
Monypenny, J;
Evans, R;
Male, V;
Gordon, P;
... Ng, T; + view all
(2017)
RORγt+ innate lymphoid cells promote lymph node metastasis of breast cancers.
Cancer Research
, 77
(5)
pp. 1083-1096.
10.1158/0008-5472.CAN-16-0598.
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Jamal-Hanjani, M;
Thanopoulou, E;
Peggs, KS;
Quezada, SA;
Swanton, C;
(2013)
Tumour heterogeneity and immune-modulation.
Curr Opin Pharmacol
, 13
(4)
497 - 503.
10.1016/j.coph.2013.04.006.
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Jamal-Hanjani, M;
Wilson, GA;
McGranahan, N;
Birkbak, NJ;
Watkins, TBK;
Veeriah, S;
Shafi, S;
... Swanton, C; + view all
(2017)
Tracking the Evolution of Non-Small-Cell Lung Cancer.
New England Journal of Medicine
, 376
(22)
pp. 2109-2121.
10.1056/NEJMoa1616288.
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Joshi, K;
Chain, BM;
Peggs, KS;
Quezada, SA;
(2017)
The "Achilles Heel" of Cancer and Its Implications for the Development of Novel Immunotherapeutic Strategies.
Cold Spring Harbor Perspectives in Medicine
10.1101/cshperspect.a027086.
(In press).
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Joshi, K;
Robert de Massy, M;
Ismail, M;
Reading, JL;
Uddin, I;
Woolston, A;
Hatipoglu, E;
... Chain, B; + view all
(2019)
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Nature Medicine
, 25
pp. 1549-1559.
10.1038/s41591-019-0592-2.
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Klebanoff, CA;
Chandran, SS;
Baker, BM;
Quezada, SA;
Ribas, A;
(2023)
T cell receptor therapeutics: immunological targeting of the intracellular cancer proteome.
Nature Reviews Drug Discovery
, 22
(12)
pp. 996-1017.
10.1038/s41573-023-00809-z.
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Kos, K;
Aslam, MA;
van de Ven, R;
Wellenstein, MD;
Pieters, W;
van Weverwijk, A;
Duits, DEM;
... de Visser, KE; + view all
(2022)
Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche.
Cell Reports
, 38
(9)
, Article 110447. 10.1016/j.celrep.2022.110447.
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Lee, L;
Alrasheed, N;
Khandelwal, G;
Fitzsimons, E;
Richards, H;
Wilson, W;
Chavda, SJ;
... Yong, K; + view all
(2021)
Increased Immune-Regulatory Receptor Expression on Effector T Cells as Early Indicators of Relapse Following Autologous Stem Cell Transplantation for Multiple Myeloma.
Frontiers Immunology
, 12
, Article 618610. 10.3389/fimmu.2021.618610.
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Leone, Gianmarco;
Wong, Yien Ning Sophia;
Jones, Robert J;
Sankey, Peter;
Josephs, Debra H;
Crabb, Simon J;
Harris, Louise;
... Linch, Mark D; + view all
(2025)
Nivolumab and Ipilimumab for Metastatic Castration-Resistant Prostate Cancer With an Immunogenic Signature: The Multicenter, Two-Cohort, Phase II NEPTUNES Study.
Journal of Clinical Oncology
, 43
(28)
10.1200/JCO-24-02637.
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Linch, M;
Goh, G;
Hiley, C;
Shanmugabavan, Y;
McGranahan, N;
Rowan, A;
Wong, YNS;
... Swanton, C; + view all
(2017)
Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters.
Annals of Oncology
, 28
(10)
pp. 2472-2480.
10.1093/annonc/mdx355.
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Litchfield, K;
Reading, JL;
Lim, EL;
Xu, H;
Liu, P;
Al-Bakir, M;
Wong, YNS;
... Swanton, C; + view all
(2020)
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity.
Nature Communications
, 11
, Article 3800. 10.1038/s41467-020-17526-5.
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Litchfield, K;
Reading, JL;
Puttick, C;
Thakkar, K;
Abbosh, C;
Bentham, R;
Watkins, TBK;
... Swanton, C; + view all
(2021)
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.
Cell
, 184
(3)
596-614.e14.
10.1016/j.cell.2021.01.002.
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Litchfield, K;
Stanislaw, S;
Spain, L;
Gallegos, LL;
Rowan, A;
Schnidrig, D;
Rosenbaum, H;
... Turajlic, S; + view all
(2020)
Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue.
Cell Reports
, 31
(5)
p. 107550.
10.1016/j.celrep.2020.107550.
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Lopez, Ernesto;
Karattil, Rajesh;
Nannini, Francesco;
Weng-Kit Cheung, Gordon;
Denzler, Lilian;
Galvez-Cancino, Felipe;
Quezada, Sergio;
(2023)
Inhibition of lactate transport by MCT-1 blockade improves chimeric antigen receptor T-cell therapy against B-cell malignancies.
Journal for ImmunoTherapy of Cancer
, 11
(6)
, Article e006287. 10.1136/jitc-2022-006287.
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López, S;
Lim, EL;
Horswell, S;
Haase, K;
Huebner, A;
Dietzen, M;
Mourikis, TP;
... McGranahan, N; + view all
(2020)
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
Nature Genetics
, 52
(3)
pp. 283-293.
10.1038/s41588-020-0584-7.
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Marzolini, MAV;
Akarca, A;
Teng, K;
Marafioti, T;
Gohil, S;
Nathwani, A;
Newell, E;
... Peggs, K; + view all
(2018)
Cytotoxic CD4+ Cells in Chronic Lymphocytic Leukaemia: An Extended Immunophenotypic Analysis Examining Their Association with Cytomegalovirus Serostatus and Similarities with Cytotoxic CD8+ Cells.
Blood
, 132
(suppl 1)
p. 3130.
10.1182/blood-2018-99-116798.
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McGranahan, N;
Rosenthal, R;
Hiley, CT;
Rowan, AJ;
Watkins, TBK;
Wilson, GA;
Birkbak, NJ;
... Swanton, C; + view all
(2017)
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.
Cell
10.1016/j.cell.2017.10.001.
(In press).
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Menares, E;
Gálvez-Cancino, F;
Cáceres-Morgado, P;
Ghorani, E;
López, E;
Díaz, X;
Saavedra-Almarza, J;
... Lladser, A; + view all
(2019)
Tissue-resident memory CD8⁺ T cells amplify anti-tumor immunity by triggering antigen spreading through dendritic cells.
Nature Communications
, 10
(1)
, Article 4401. 10.1038/s41467-019-12319-x.
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Menezes, S;
Melandri, D;
Anselmi, G;
Perchet, T;
Loschko, J;
Dubrot, J;
Patel, R;
... Guermonprez, P; + view all
(2016)
The Heterogeneity of Ly6C(hi) Monocytes Controls Their Differentiation into iNOS(+) Macrophages or Monocyte-Derived Dendritic Cells.
Immunity
, 45
(6)
pp. 1205-1218.
10.1016/j.immuni.2016.12.001.
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Menger, L;
Sledzinska, A;
Bergerhoff, K;
Vargas, FA;
Smith, J;
Poirot, L;
Pule, M;
... Quezada, SA; + view all
(2016)
TALEN-Mediated Inactivation of PD-1 in Tumor-Reactive Lymphocytes Promotes Intratumoral T-cell Persistence and Rejection of Established Tumors.
Cancer Research
, 76
(8)
pp. 2087-2093.
10.1158/0008-5472.CAN-15-3352.
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Monypenny, J;
Milewicz, H;
Flores-Borja, F;
Weitsman, G;
Cheung, A;
Chowdhury, R;
Burgoyne, T;
... Ng, T; + view all
(2018)
ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation.
Cell Reports
, 24
(3)
pp. 630-641.
10.1016/j.celrep.2018.06.066.
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Ohs, I;
van den Broek, M;
Nussbaum, K;
Munz, C;
Arnold, SJ;
Quezada, SA;
Tugues, S;
(2016)
Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis.
Nature Communications
, 7
, Article 13708. 10.1038/ncomms13708.
|
|
|
Pacheco, R;
Quezada, SA;
Kalergis, AM;
Becker, MI;
Ferreira, J;
De Ioannes, AE;
(2021)
Allergens of the urushiol family promote mitochondrial dysfunction by inhibiting the electron transport at the level of cytochromes b and chemically modify cytochrome c1.
Biological Research
, 54
(1)
, Article 35. 10.1186/s40659-021-00357-z.
|
|
|
Pennycuick, A;
Teixeira, VH;
AbdulJabbar, K;
Raza, SEA;
Lund, T;
Akarca, AU;
Rosenthal, R;
... Janes, SM; + view all
(2020)
Immune surveillance in clinical regression of pre-invasive squamous cell lung cancer.
Cancer Discovery
, 10
(10)
pp. 1489-1499.
10.1158/2159-8290.CD-19-1366.
|
|
Philip, B;
Kokalaki, E;
Mekkaoui, L;
Thomas, S;
Straathof, K;
Flutter, B;
Marin, V;
... Pule, M; + view all
(2014)
A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy.
Blood
, 124
(8)
1277 - 1287.
10.1182/blood-2014-01-545020.
|
|
Puttick, Clare;
Jones, Thomas P;
Leung, Michelle M;
Galvez-Cancino, Felipe;
Liu, Jiali;
Varas-Godoy, Manuel;
Rowan, Andrew;
... Mcgranahan, Nicholas; + view all
(2024)
MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution.
Nature Genetics
, 56
(10)
pp. 2121-2131.
10.1038/s41588-024-01883-8.
|
|
|
Quezada, SA;
Peggs, KS;
(2018)
Lost in Translation: Deciphering the mechanism of action of anti-human CTLA-4.
Clinical Cancer Research
10.1158/1078-0432.CCR-18-2509.
(In press).
|
|
Quezada, SA;
Peggs, KS;
(2013)
Exploiting CTLA-4, PD-1 and PD-L1 to reactivate the host immune response against cancer.
British Journal of Cancer
, 108
(8)
1560 -1565.
10.1038/bjc.2013.117.
|
|
|
Quezada, SA;
Peggs, KS;
Curran, MA;
Allison, JP;
(2006)
CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells.
J CLIN INVEST
, 116
(7)
1935 - 1945.
10.1172/JCI27745.
|
|
|
Reading, JL;
Gálvez-Cancino, F;
Swanton, RC;
Lladser, A;
Peggs, K;
Quezada, S;
(2018)
The function and dysfunction of memory CD8+ T cells in tumor immunity.
Immunological Reviews
, 283
(1)
pp. 194-212.
10.1111/imr.12657.
|
|
Reading, JL;
Quezada, SA;
(2016)
Too Much of a Good Thing? Chronic IFN Fuels Resistance to Cancer Immunotherapy.
Immunity
, 45
(6)
pp. 1181-1183.
10.1016/j.immuni.2016.12.004.
|
|
Rosenthal, R;
Cadieux, EL;
Salgado, R;
Bakir, MA;
Moore, DA;
Hiley, CT;
Lund, T;
... TRACERx consortium; + view all
(2019)
Neoantigen-directed immune escape in lung cancer evolution.
Nature
10.1038/s41586-019-1032-7.
(In press).
|
|
Royle, KL;
Coulson, AB;
Ramasamy, K;
Cairns, DA;
Hockaday, A;
Quezada, S;
Drayson, M;
... Yong, K; + view all
(2022)
Risk and response adapted therapy following autologous stem cell transplant in patients with newly diagnosed multiple myeloma (RADAR (UK-MRA Myeloma XV Trial): study protocol for a phase II/III randomised controlled trial.
BMJ open
, 12
(11)
, Article e063037. 10.1136/bmjopen-2022-063037.
|
|
Samson, A;
Scott, KJ;
Taggart, D;
West, EJ;
Wilson, E;
Nuovo, GJ;
Thomson, S;
... Melcher, AA; + view all
(2018)
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade.
Science Translational Medicine
, 10
(422)
, Article eaam7577. 10.1126/scitranslmed.aam7577.
|
|
|
Sanchez-Paulete, AR;
Teijeira, A;
Quetglas, JI;
Rodriguez-Ruiz, ME;
Sanchez-Arraez, A;
Labiano, S;
Etxeberria, I;
... Melero, I; + view all
(2018)
Intratumoral immunotherapy with XCL1 and sFlt3L encoded in recombinant Semliki Forest Virus-derived vectors fosters dendritic cell-mediated T cell cross-priming.
Cancer Research
10.1158/0008-5472.CAN-18-0933.
|
|
Śledzińska, A;
Vila de Mucha, M;
Bergerhoff, K;
Hotblack, A;
Demane, DF;
Ghorani, E;
Akarca, AU;
... Quezada, SA; + view all
(2020)
Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4⁺ T Cells.
Immunity
, 52
(1)
151-166.e6.
10.1016/j.immuni.2019.12.007.
|
|
Solomon, I;
Amann, M;
Goubier, A;
Vargas, FA;
Zervas, D;
Qing, C;
Henry, JY;
... Quezada, SA; + view all
(2020)
CD25-Treg-depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity.
Nature Cancer
, 1
(12)
pp. 1153-1166.
10.1038/s43018-020-00133-0.
|
|
|
Swanton, C;
Bernard, E;
Abbosh, C;
André, F;
Auwerx, J;
Balmain, A;
Bar-Sagi, D;
... Hanahan, D; + view all
(2024)
Embracing cancer complexity: Hallmarks of systemic disease.
Cell
, 187
(7)
pp. 1589-1616.
10.1016/j.cell.2024.02.009.
|
|
Turajlic, S;
Litchfield, K;
Xu, H;
Rosenthal, R;
McGranahan, N;
Reading, JL;
Wong, YNS;
... Swanton, C; + view all
(2017)
Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis.
The Lancet Oncology
, 18
(8)
pp. 1009-1021.
10.1016/S1470-2045(17)30516-8.
|
|
|
van Tienhoven, R;
Jansen, DTSL;
Park, M;
Williams, JC;
Larkin, J;
Quezada, SA;
Roep, BO;
(2024)
Induction of islet autoimmunity to defective ribosomal product of the insulin gene as neoantigen after anti-cancer immunotherapy leading to autoimmune diabetes.
Frontiers in Immunology
, 15
, Article 1384406. 10.3389/fimmu.2024.1384406.
|
|
Vargas, FA;
Furness, AJS;
Litchfield, K;
Joshi, K;
Rosenthal, R;
Ghorani, E;
Solomon, I;
... Quezada, SA; + view all
(2018)
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.
Cancer Cell
, 33
(4)
pp. 649-663.
10.1016/j.ccell.2018.02.010.
|
|
|
Vargas, FA;
Furness, AJS;
Solomon, I;
Joshi, K;
Mekkaoui, L;
Lesko, MH;
Rota, EM;
... Quezada, SA; + view all
(2017)
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.
Immunity
, 46
(4)
pp. 577-586.
10.1016/j.immuni.2017.03.013.
|
|
|
Venkatesan, S;
Rosenthal, R;
Kanu, N;
McGranahan, N;
Bartek, J;
Quezada, SA;
Hare, J;
... Swanton, C; + view all
(2018)
APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution.
Annals of Oncology
, 29
(3)
pp. 563-572.
10.1093/annonc/mdy003.
|
|
|
Vicencio, JM;
Evans, R;
Green, R;
An, Z;
Deng, J;
Treacy, C;
Mustapha, R;
... Ng, T; + view all
(2022)
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans.
Cell Death & Disease
, 13
(3)
, Article 274. 10.1038/s41419-022-04701-3.
|
|
|
Wong, YNS;
Joshi, K;
Khetrapal, P;
Ismail, M;
Reading, JL;
Sunderland, MW;
Georgiou, A;
... Quezada, SA; + view all
(2018)
Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment.
Journal of Experimental Medicine
, 215
(11)
pp. 2748-2759.
10.1084/jem.20181003.
|
|
|
Wong, YNS;
Joshi, K;
Pule, M;
Peggs, KS;
Swanton, C;
Quezada, SA;
Linch, M;
(2017)
Evolving adoptive cellular therapies in urological malignancies.
Lancet Oncology
, 18
(6)
E341-E353.
10.1016/S1470-2045(17)30327-3.
|
|
|
Woolston, A;
Khan, K;
Spain, G;
Barber, LJ;
Griffiths, B;
Gonzalez-Exposito, R;
Hornsteiner, L;
... Gerlinger, M; + view all
(2019)
Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer.
Cancer Cell
, 36
(1)
35-50e9.
10.1016/j.ccell.2019.05.013.
|
|
|
Wu, Yin;
Biswas, Dhruva;
Usaite, Ieva;
Angelova, Mihaela;
Boeing, Stefan;
Karasaki, Takahiro;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2022)
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer.
Nature Cancer
, 3
pp. 696-709.
10.1038/s43018-022-00376-z.
|
|
Zelenay, S;
van der Veen, AG;
Boettcher, JP;
Snelgrove, KJ;
Rogers, N;
Acton, SE;
Chakravarty, P;
... Reis e Sousa, C; + view all
(2015)
Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.
Cell
, 162
(6)
pp. 1257-1270.
10.1016/j.cell.2015.08.015.
|
|
Zhao, Y;
Fu, X;
Lopez, JI;
Rowan, A;
Au, L;
Fendler, A;
Hazell, S;
... Litchfield, K; + view all
(2021)
Selection of metastasis competent subclones in the tumour interior.
Nature Ecology & Evolution
, 5
pp. 1033-1045.
10.1038/s41559-021-01456-6.
|
|
Working / discussion paper
|
Garcia-Diaz, Claudia;
Mereu, Elisabetta;
Clements, Melanie;
Pöysti, Anni;
Galvez-Cancino, Felipe;
Castillo, Simon;
Courtot, Lilas;
... Parrinello, Simona; + view all
(2021)
Glioblastoma cell fate is differentially regulated by the microenvironments of the tumour bulk and infiltrative margin.
bioRxiv: Cold Spring Harbor, NY, USA.
|
|
Conference item
|
Vesely, C;
Childs, A;
Wong, YNS;
Ogunbiyi, O;
Gander, A;
Luong, T;
Thirlwell, C;
... Meyer, T; + view all
(2018)
Systematic Evaluation of the Immune Microenvironment of Neuroendocrine Tumors (NET).
Presented at: 15th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease, Barcelona, Spain.
|
Thesis
|
Bergerhoff, KF;
(2016)
Cellular and molecular events controlling acquisition of cytotoxic activity by melanoma-reactive CD4⁺ T cells in vivo.
Doctoral thesis , UCL (University College London).
|
|
Roddie, C;
(2016)
Targeting interference of CTLA-4 co-inhibition to tumour specific T cells to enhance activity and reduce toxicity.
Doctoral thesis , UCL (University College London).
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