Browse by UCL people
Group by: Type | Date
Number of items: 67.
Article
Adams, RA;
Huys, QJ;
Roiser, JP;
(2015)
Computational Psychiatry: towards a mathematically informed understanding of mental illness.
Journal of Neurology, Neurosurgery and Psychiatry
10.1136/jnnp-2015-310737.
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Atiya, NAA;
Huys, QJM;
Dolan, RJ;
Fleming, SM;
(2021)
Explaining distortions in metacognition with an attractor network model of decision uncertainty.
PLoS Computational Biology
, 17
(7)
, Article e1009201. 10.1371/journal.pcbi.1009201.
(In press).
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Berwian, IM;
Tröndle, M;
de Miquel, C;
Ziogas, A;
Stefanics, G;
Walter, H;
Stephan, KE;
(2024)
Emotion-Induced Frontal Alpha Asymmetry as a Candidate Predictor of Relapse After Discontinuation of Antidepressant Medication.
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
, 9
(8)
pp. 809-818.
10.1016/j.bpsc.2024.05.001.
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Berwian, IM;
Wenzel, JG;
Kuehn, L;
Schnuerer, I;
Seifritz, E;
Stephan, KE;
Walter, H;
(2022)
Low predictive power of clinical features for relapse prediction after antidepressant discontinuation in a naturalistic setting.
Scientific Reports
, 12
, Article 11171. 10.1038/s41598-022-13893-9.
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Berwian, IM;
Walter, H;
Seifritz, E;
Huys, QJM;
(2017)
Predicting relapse after antidepressant withdrawal – a systematic review.
Psychological Medicine
, 47
(3)
pp. 426-437.
10.1017/S0033291716002580.
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Berwian, IM;
Wenzel, JG;
Collins, AGE;
Seifritz, E;
Stephan, KE;
Walter, H;
Huys, QJM;
(2020)
Computational Mechanisms of Effort and Reward Decisions in Patients With Depression and Their Association With Relapse After Antidepressant Discontinuation.
JAMA Psychiatry
10.1001/jamapsychiatry.2019.4971.
(In press).
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Berwian, IM;
Wenzel, JG;
Kuehn, L;
Schnuerer, I;
Kasper, L;
Veer, IM;
Seifritz, E;
... Huys, QJM; + view all
(2020)
The relationship between resting-state functional connectivity, antidepressant discontinuation and depression relapse.
Scientific Reports
, 10
, Article 22346. 10.1038/s41598-020-79170-9.
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Browning, M;
Paulus, M;
Huys, QJM;
(2023)
What is Computational Psychiatry Good For?
Biological Psychiatry
, 93
(8)
pp. 658-660.
10.1016/j.biopsych.2022.08.030.
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Browning, M;
Carter, CS;
Chatham, C;
Den Ouden, H;
Gillan, CM;
Baker, JT;
Chekroud, AM;
... Paulus, M; + view all
(2020)
Realizing the Clinical Potential of Computational Psychiatry: Report From the Banbury Center Meeting, February 2019.
Biological Psychiatry
, 88
(2)
e5-e10.
10.1016/j.biopsych.2019.12.026.
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Charpentier, CJ;
Faulkner, P;
Pool, ER;
Ly, V;
Tollenaar, MS;
Kluen, LM;
Fransen, A;
... O'Doherty, JP; + view all
(2021)
How Representative are Neuroimaging Samples? Large-Scale Evidence for Trait Anxiety Differences Between fMRI and Behaviour-Only Research Participants.
Social Cognitive and Affective Neuroscience
10.1093/scan/nsab057.
(In press).
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Chen, H;
Kuitunen-Paul, S;
Garbusow, M;
Lukezic, M;
Huys, QJM;
Rapp, MA;
Heinz, A;
(2025)
Changes in Model-Based and Model-Free Control Prospectively Predict Drinking Trajectories in Young Men.
Biological Psychiatry
10.1016/j.biopsych.2025.06.028.
(In press).
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Chen, H;
Mojtahedzadeh, N;
Belanger, MJ;
Nebe, S;
Kuitunen-Paul, S;
Sebold, M;
Garbusow, M;
... Smolka, MN; + view all
(2021)
Model-Based and Model-Free Control Predicts Alcohol Consumption Developmental Trajectory in Young Adults: A 3-Year Prospective Study.
Biological Psychiatry
, 89
(10)
pp. 980-989.
10.1016/j.biopsych.2021.01.009.
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Chen, Hao;
Belanger, Matthew J;
Garbusow, Maria;
Kuitunen-Paul, Soeren;
Huys, Quentin JM;
Heinz, Andreas;
Rapp, Michael A;
(2023)
Susceptibility to interference between Pavlovian and instrumental control predisposes risky alcohol use developmental trajectory from ages 18 to 24.
Addiction Biology
, 28
(2)
, Article e13263. 10.1111/adb.13263.
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Chen, K;
Garbusow, M;
Sebold, M;
Kuitunen-Paul, S;
Smolka, MN;
Huys, QJM;
Zimmermann, US;
... Heinz, A; + view all
(2023)
Alcohol Approach Bias Is Associated With Both Behavioral and Neural Pavlovian-to-Instrumental Transfer Effects in Alcohol-Dependent Patients.
Biological Psychiatry Global Open Science
, 3
(3)
pp. 443-450.
10.1016/j.bpsgos.2022.03.014.
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Chen, K;
Schlagenhauf, F;
Sebold, M;
Kuitunen-Paul, S;
Chen, H;
Huys, QJM;
Heinz, A;
... Garbusow, M; + view all
(2022)
The Association of Non–Drug-Related Pavlovian-to-Instrumental Transfer Effect in Nucleus Accumbens With Relapse in Alcohol Dependence: A Replication.
Biological Psychiatry
, 93
(6)
pp. 558-565.
10.1016/j.biopsych.2022.09.017.
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Chen, H;
Nebe, S;
Mojtahedzadeh, N;
Kuitunen-Paul, S;
Garbusow, M;
Schad, DJ;
Rapp, MA;
... Smolka, MN; + view all
(2020)
Susceptibility to interference between Pavlovian and instrumental control is associated with early hazardous alcohol use.
Addiction Biology
, Article e12983. 10.1111/adb.12983.
(In press).
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Dayan, P;
Huys, QJM;
(2008)
Serotonin, inhibition, and negative mood.
PLoS Computational Biology
, 4
(2)
, Article e4. 10.1371/journal.pcbi.0040004.
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Durstewitz, D;
Huys, QJM;
Koppe, G;
(2020)
Psychiatric Illnesses as Disorders of Network Dynamics.
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
10.1016/j.bpsc.2020.01.001.
(In press).
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Ebrahimi, C;
Garbusow, M;
Sebold, M;
Chen, K;
Smolka, MN;
Huys, QJM;
Zimmermann, US;
... Heinz, A; + view all
(2023)
Elevated Amygdala Responses During De Novo Pavlovian Conditioning in Alcohol Use Disorder Are Associated With Pavlovian-to-Instrumental Transfer and Relapse Latency.
Biological Psychiatry Global Open Science
10.1016/j.bpsgos.2023.02.003.
(In press).
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Erdmann, Tore;
Berwian, Isabel M;
Stephan, Klaas Enno;
Seifritz, Erich;
Walter, Henrik;
Huys, Quentin JM;
(2024)
Amygdala Reactivity, Antidepressant Discontinuation, and Relapse.
JAMA Psychiatry
, 81
(11)
pp. 1081-1089.
10.1001/jamapsychiatry.2024.2136.
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Faulkner, P;
Huys, QJM;
Renz, D;
Eshel, N;
Pilling, S;
Dayan, P;
Roiser, JP;
(2021)
A comparison of 'pruning' during multi-step planning in depressed and healthy individuals.
Psychological Medicine
10.1017/S0033291721000799.
(In press).
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Friedel, E;
Schlagenhauf, F;
Beck, A;
Dolan, RJ;
Huys, QJ;
Rapp, MA;
Heinz, A;
(2015)
The effects of life stress and neural learning signals on fluid intelligence.
Eur Arch Psychiatry Clin Neurosci
, 265
(1)
35 - 43.
10.1007/s00406-014-0519-3.
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Garbusow, M;
Nebe, S;
Sommer, C;
Kuitunen-Paul, S;
Sebold, M;
Schad, DJ;
Friedel, E;
... Heinz, A; + view all
(2019)
Pavlovian-To-Instrumental Transfer and Alcohol Consumption in Young Male Social Drinkers: Behavioral, Neural and Polygenic Correlates.
Journal of Clinical Medicine
, 8
(8)
, Article 1188. 10.3390/jcm8081188.
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Geurts, DEM;
Van den Heuvel, TJ;
Huys, QJM;
Verkes, RJ;
Cools, R;
(2022)
Amygdala response predicts clinical symptom reduction in patients with borderline personality disorder: A pilot fMRI study.
Frontiers in Behavioral Neuroscience
, 16
, Article 938403. 10.3389/fnbeh.2022.938403.
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Geurts, DEM;
von Borries, K;
Huys, QJM;
Bulten, BH;
Verkes, RJ;
Cools, R;
(2022)
Psychopathic tendency in violent offenders is associated with reduced aversive Pavlovian inhibition of behavior and associated striatal BOLD signal.
Frontiers in Behavioral Neuroscience
, 16
, Article 963776. 10.3389/fnbeh.2022.963776.
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Grosskurth, ED;
Bach, DR;
Economides, M;
Huys, QJM;
Holper, L;
(2019)
No substantial change in the balance between model-free and model-based control via training on the two-step task.
PLoS Computational Biology
, 15
(11)
, Article e1007443. 10.1371/journal.pcbi.1007443.
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Guitart-Masip, M;
Economides, M;
Huys, QJM;
Chowdhury, R;
Dolan, RJ;
Dayan, P;
Frank, MJ;
(2014)
Differential, but not opponent, effects of l-DOPA and citalopram on action learning with reward and punishment.
Psychopharmacology
, 231
(5)
955 - 966.
10.1007/s00213-013-3313-4.
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Guitart-Masip, M;
Fuentemilla, L;
Bach, DR;
Huys, QJM;
Dayan, P;
Dolan, RJ;
Duzel, E;
(2011)
Action Dominates Valence in Anticipatory Representations in the Human Striatum and Dopaminergic Midbrain.
Journal of Neuroscience
, 31
(21)
7867- 7875.
10.1523/JNEUROSCI.6376-10.2011.
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Hall, Anna F;
Browning, Michae;
Huys, Quentin JM;
(2024)
The computational structure of consummatory anhedonia.
Trends in Cognitive Sciences
10.1016/j.tics.2024.01.006.
(In press).
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Huys, QJM;
Russek, EM;
Abitante, G;
Kahnt, T;
Gollan, JK;
(2022)
Components of Behavioral Activation Therapy for Depression Engage Specific Reinforcement Learning Mechanisms in a Pilot Study.
Computational Psychiatry
, 6
(1)
pp. 238-255.
10.5334/cpsy.81.
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Huys, Quentin JM;
(2022)
Is there mathematics to madness?
Brain
, 145
(6)
pp. 2227-2228.
10.1093/brain/awac047.
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Huys, Quentin JM;
Browning, Michael;
(2025)
Trials for computational psychiatry.
Nature Computational Science
, 5
pp. 841-843.
10.1038/s43588-025-00879-6.
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Huys, Quentin JM;
Browning, Michael;
(2022)
A Computational View on the Nature of Reward and Value in Anhedonia.
Current Topics in Behavioral Neurosciences
, 58
pp. 421-442.
10.1007/7854_2021_290.
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Huys, QJ;
Eshel, N;
O'Nions, E;
Sheridan, L;
Dayan, P;
Roiser, JP;
(2012)
Bonsai trees in your head: how the pavlovian system sculpts goal-directed choices by pruning decision trees.
PLoS Comput Biol
, 8
(3)
, Article e1002410. 10.1371/journal.pcbi.1002410.
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Huys, QJ;
Gölzer, M;
Friedel, E;
Heinz, A;
Cools, R;
Dayan, P;
Dolan, RJ;
(2016)
The specificity of Pavlovian regulation is associated with recovery from depression.
Psychological Medicine
, 46
(5)
pp. 1027-1035.
10.1017/S0033291715002597.
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Huys, QJ;
Pizzagalli, DA;
Bogdan, R;
Dayan, P;
(2013)
Mapping anhedonia onto reinforcement learning: A behavioural meta-analysis.
Biology of Mood & Anxiety Disorders
, 3
(1)
, Article 12. 10.1186/2045-5380-3-12.
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Huys, QJM;
Browning, M;
Paulus, M;
Frank, MJ;
(2021)
Advances in the computational understanding of mental illness.
Neuropsychopharmacology
, 46
pp. 3-19.
10.1038/s41386-020-0746-4.
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Huys, QJM;
Cools, R;
Golzer, M;
Friedel, E;
Heinz, A;
Dolan, RJ;
Dayan, P;
(2011)
Disentangling the Roles of Approach, Activation and Valence in Instrumental and Pavlovian Responding.
PLOS COMPUT BIOL
, 7
(4)
, Article e1002028. 10.1371/journal.pcbi.1002028.
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Huys, QJM;
Renz, D;
(2017)
A Formal Valuation Framework for Emotions and Their Control.
Biological Psychiatry
, 82
(6)
pp. 413-420.
10.1016/j.biopsych.2017.07.003.
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Kirschner, M;
Sladky, R;
Haugg, A;
Stämpfli, P;
Jehli, E;
Hodel, M;
Engeli, E;
... Herdener, M; + view all
(2018)
Self-regulation of the dopaminergic reward circuit in cocaine users with mental imagery and neurofeedback.
EBioMedicine
10.1016/j.ebiom.2018.10.052.
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Kühnel, A;
Teckentrup, V;
Neuser, MP;
Huys, QJM;
Burrasch, C;
Walter, M;
Kroemer, NB;
(2020)
Stimulation of the vagus nerve reduces learning in a go/no-go reinforcement learning task.
European Neuropsychopharmacology
, 35
pp. 17-29.
10.1016/j.euroneuro.2020.03.023.
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Lally, N;
Huys, QJM;
Eshel, N;
Faulkner, P;
Dayan, P;
Roiser, JP;
(2017)
The neural basis of aversive Pavlovian guidance during planning.
Journal of Neuroscience
, 37
(42)
pp. 10215-10229.
10.1523/JNEUROSCI.0085-17.2017.
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Leong, Ian Lam;
Ng, Tsz Huen;
Sen, Kunal;
Burchill, Ella;
Costello, Harry;
Badenoch, James B;
Coebergh, Jan;
... Rogers, Jonathan P; + view all
(2025)
Reduced striatal dopamine transmission as a transdiagnostic substrate of psychomotor retardation.
Brain
, Article awaf335. 10.1093/brain/awaf335.
(In press).
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Mihalik, A;
Adams, RA;
Huys, Q;
(2020)
Canonical correlation analysis for identifying biotypes of depression.
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
, 5
(5)
pp. 478-480.
10.1016/j.bpsc.2020.02.002.
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Mishchanchuk, Karyna;
Gregoriou, Gabrielle;
Qü, Albert;
Kastler, Alizée;
Huys, Quentin JM;
Wilbrecht, Linda;
MacAskill, Andrew F;
(2024)
Hidden state inference requires abstract contextual representations in the ventral hippocampus.
Science
, 386
(6724)
pp. 926-932.
10.1126/science.adq5874.
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Mkrtchian, A;
Qiu, Z;
Abir, Y;
Erdmann, T;
Dercon, Q;
Sedlinska, T;
Browning, M;
... Huys, QJM; + view all
(2025)
Differential Associations of Dopamine and Serotonin With Reward and Punishment Processes in Humans: A Systematic Review and Meta-Analysis.
JAMA Psychiatry
10.1001/jamapsychiatry.2025.0839.
(In press).
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Norbury, Agnes;
Hauser, Tobias U;
Fleming, Stephen M;
Dolan, Raymond J;
Huys, Quentin JM;
(2024)
Different components of cognitive-behavioral therapy affect specific cognitive mechanisms.
Science Advances
, 10
(13)
, Article eadk3222. 10.1126/sciadv.adk3222.
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Nord, CL;
Lawson, RP;
Huys, QJM;
Pilling, S;
Roiser, JP;
(2018)
Depression is associated with enhanced aversive Pavlovian control over instrumental behaviour.
Scientific Reports
, 8
, Article 12582. 10.1038/s41598-018-30828-5.
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Nour, MM;
Huys, QJM;
(2023)
Natural Language Processing in Psychiatry: A Field at an Inflection Point.
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
, 8
(10)
pp. 979-981.
10.1016/j.bpsc.2023.08.001.
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Ousdal, OT;
Huys, QJ;
Milde, AM;
Craven, AR;
Ersland, L;
Endestad, T;
Melinder, A;
... Dolan, RJ; + view all
(2018)
The impact of traumatic stress on Pavlovian biases.
Psychological Medicine
, 48
(2)
pp. 327-336.
10.1017/S003329171700174X.
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Ousdal, OT;
Milde, AM;
Craven, AR;
Ersland, L;
Endestad, T;
Melinder, A;
Huys, QJ;
(2019)
Prefrontal Glutamate Levels Predict Altered Amygdala-prefrontal Connectivity in Traumatized Youths.
Psychological Medicine
, 49
(11)
pp. 1822-1830.
10.1017/S0033291718002519.
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Pezzoli, P;
Parsons, S;
Kievit, RA;
Astle, DE;
Huys, QJM;
Steinbeis, N;
Viding, E;
(2023)
Challenges and Solutions to the Measurement of Neurocognitive Mechanisms in Developmental Settings.
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
10.1016/j.bpsc.2023.03.011.
(In press).
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Poldrack, RA;
Feingold, F;
Frank, MJ;
Gleeson, P;
De Hollander, G;
Huys, QJM;
Love, BC;
... Cohen, JD; + view all
(2019)
The Importance of Standards for Sharing of Computational Models and Data.
Computational Brain & Behavior
, 2
pp. 229-232.
10.1007/s42113-019-00062-x.
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Reiter, AM;
Atiya, NA;
Berwian, IM;
Huys, QJ;
(2021)
Neuro-cognitive processes as mediators of psychological treatment effects.
Current Opinion in Behavioral Sciences
, 38
pp. 103-109.
10.1016/j.cobeha.2021.02.007.
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Rupprechter, S;
Stankevicius, A;
Huys, QJM;
Series, P;
Steele, JD;
(2020)
Abnormal reward valuation and event-related connectivity in unmedicated major depressive disorder.
Psychological Medicine
10.1017/S0033291719003799.
(In press).
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Rupprechter, S;
Stankevicius, A;
Huys, QJM;
Steele, JD;
Seriès, P;
(2018)
Major Depression Impairs the Use of Reward Values for Decision-Making.
Scientific Reports
, 8
(1)
, Article 13798. 10.1038/s41598-018-31730-w.
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Russek, EM;
Moran, R;
McNamee, D;
Reiter, A;
Liu, Y;
Dolan, RJ;
Huys, QJM;
(2020)
Opportunities for emotion and mental health research in the resource-rationality framework.
Behavioral and Brain Sciences
, 43
, Article e21. 10.1017/S0140525X19001663.
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Rutledge, RB;
Chekroud, AM;
Huys, QJ;
(2019)
Machine learning and big data in psychiatry: toward clinical applications.
Current Opinion in Neurobiology
, 55
pp. 152-159.
10.1016/j.conb.2019.02.006.
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Schad, DJ;
Rapp, MA;
Garbusow, M;
Nebe, S;
Sebold, M;
Obst, E;
Sommer, C;
... Huys, QJM; + view all
(2020)
Dissociating neural learning signals in human sign- and goal-trackers.
Nature Human Behaviour
, 4
pp. 201-214.
10.1038/s41562-019-0765-5.
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Schulz, E;
Wu, CM;
Huys, QJM;
Krause, A;
Speekenbrink, M;
(2018)
Generalization and Search in Risky Environments.
Cognitive Science
10.1111/cogs.12695.
(In press).
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Sebold, M;
Chen, H;
Önal, A;
Kuitunen-Paul, S;
Mojtahedzadeh, N;
Garbusow, M;
Nebe, S;
... Heinz, A; + view all
(2022)
Stronger Prejudices Are Associated With Decreased Model-Based Control.
Frontiers in Psychology
, 12
, Article 767022. 10.3389/fpsyg.2021.767022.
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Sebold, M;
Garbusow, M;
Cerci, D;
Chen, K;
Sommer, C;
Huys, QJM;
Nebe, S;
... Friedel, E; + view all
(2021)
Association of the OPRM1 A118G polymorphism and Pavlovian-to-instrumental transfer: Clinical relevance for alcohol dependence.
Journal of Psychopharmacology
10.1177/0269881121991992.
(In press).
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Sommer, C;
Garbusow, M;
Jünger, E;
Pooseh, S;
Bernhardt, N;
Birkenstock, J;
Schad, DJ;
... Zimmermann, US; + view all
(2017)
Strong seduction: impulsivity and the impact of contextual cues on instrumental behavior in alcohol dependence.
Translational Psychiatry
, 7
(8)
, Article e1183. 10.1038/tp.2017.158.
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Stephan, KE;
Schlagenhauf, F;
Huys, QJ;
Raman, S;
Aponte, EA;
Brodersen, KH;
Rigoux, L;
... Heinz, A; + view all
(2017)
Computational neuroimaging strategies for single patient predictions.
NeuroImage
, 145
(Pt B)
pp. 180-199.
10.1016/j.neuroimage.2016.06.038.
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Yip, SW;
Barch, DM;
Chase, HW;
Flagel, S;
Huys, QJM;
Konova, AB;
Montague, R;
(2023)
From Computation to Clinic.
Biological Psychiatry Global Open Science
, 3
(3)
pp. 319-328.
10.1016/j.bpsgos.2022.03.011.
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Proceedings paper
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Schulz, E;
Huys, QJM;
Bach, DR;
Speekenbrink, M;
Krause, A;
(2016)
Better safe than sorry: Risky function exploitation through safe optimization.
In:
Proceedings of the 38th Annual Meeting of the Cognitive Science Society.
(pp. pp. 1140-1145).
Cognitive Science Society: Austin, TX.
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Thesis
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Huys, Q;
(2007)
Reinforcers and control: Towards a computational aetiology of depression.
Doctoral thesis , UCL (University College London).
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