Browse by UCL people
Group by: Type | Date
Number of items: 35.
2025
Woodridge, Laurel;
Tektonidou, Maria G;
Robinson, George A;
Peng, Junjie;
Coelewij, Leda;
Martin-Gutierrez, Lucia;
Navarro, Elvira Chocano;
... Jury, Elizabeth C; + view all
(2025)
Subclinical Atherosclerosis Risk Can Be Predicted in Female Patients With Systemic Lupus Erythematosus Using Metabolomic Signatures: An Observational Study.
Journal of the American Heart Association
, 14
(8)
, Article e036507. 10.1161/JAHA.124.036507.
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2022
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Robinson, G;
Pineda-Torra, I;
Ciurtin, C;
Jury, EC;
(2022)
Lipid metabolism in autoimmune rheumatic disease: implications for modern and conventional therapies.
Journal of Clinical Investigation
, 132
(2)
, Article e148552. 10.1172/JCI148552.
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Robinson, GA;
Peng, J;
Pineda-Torra, I;
Ciurtin, C;
Jury, EC;
(2022)
Metabolomics defines complex patterns of dyslipidaemia in juvenile-sle patients associated with inflammation and potential cardiovascular disease risk.
Metabolites
, 12
(1)
, Article 3. 10.3390/metabo12010003.
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Spitschan, Manuel;
Santhi, Nayantara;
Ahluwalia, Amrita;
Fischer, Dorothee;
Hunt, Lilian;
Karp, Natasha;
Lévi, Francis;
... White, Rhiannon; + view all
(2022)
Science Forum: Sex differences and sex bias in human circadian and sleep physiology research.
Elife
, 11
, Article e65419. 10.7554/eLife.65419.
(In press).
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2021
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Coelewij, L;
Waddington, KE;
Robinson, GA;
Chocano, E;
McDonnell, T;
Farinha, F;
Peng, J;
... Pineda-Torra, I; + view all
(2021)
Serum Metabolomic Signatures Can Predict Subclinical Atherosclerosis in Patients With Systemic Lupus Erythematosus.
Arteriosclerosis, Thrombosis, and Vascular Biology
10.1161/ATVBAHA.120.315321.
(In press).
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Fan, R;
Pineda-Torra, I;
Venteclef, N;
(2021)
Editorial: Nuclear Receptors and Coregulators in Metabolism and Immunity.
Frontiers in Endocrinology
, 12
, Article 828635. 10.3389/fendo.2021.828635.
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Parikh, C;
Ponnampalam, J;
Seligmann, G;
Coelewij, L;
Pineda-Torra, I;
Jury, E;
Ciurtin, C;
(2021)
Impact of immunogenicity on clinical efficacy and toxicity profile of biologic agents used for treatment of inflammatory arthritis in children compared to adults.
Therapeutic Advances in Musculoskeletal Disease
10.1177/1759720X211002685.
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Pineda-Torra, I;
Siddique, S;
Waddington, KE;
Farrell, R;
Jury, EC;
(2021)
Disrupted Lipid Metabolism in Multiple Sclerosis: A Role for Liver X Receptors?
Frontiers in Endocrinology
, 12
, Article 639757. 10.3389/fendo.2021.639757.
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Robinson, GA;
Peng, J;
Peckham, H;
Radziszewska, A;
Butler, G;
Pineda-Torra, I;
Jury, EC;
(2021)
Sex hormones drive changes in lipoprotein metabolism.
iScience
, Article 103257. 10.1016/j.isci.2021.103257.
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Robinson, GA;
Pineda-Torra, I;
Ciurtin, C;
Jury, EC;
(2021)
Predicting long-term cardiometabolic risk: Do childhood metabolomic signatures hold the key?
EBioMedicine
, 74
, Article 103702. 10.1016/j.ebiom.2021.103702.
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Robinson, GA;
Waddington, KE;
Coelewij, L;
Peng, J;
Naja, M;
Wincup, C;
Radziszewska, A;
... Jury, EC; + view all
(2021)
Increased apolipoprotein-B:A1 ratio predicts cardiometabolic risk in patients with juvenile onset SLE.
EBioMedicine
, Article 103243. 10.1016/j.ebiom.2021.103243.
(In press).
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Schmidt, NM;
Wing, PAC;
Diniz, MO;
Pallett, LJ;
Swadling, L;
Harris, JM;
Burton, AR;
... Maini, MK; + view all
(2021)
Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.
Nature Communications
, 12
, Article 2814. 10.1038/s41467-021-22967-7.
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Thibaut, R;
Gage, MC;
Pineda-Torra, I;
Chabrier, G;
Venteclef, N;
Alzaid, F;
(2021)
Liver macrophages and inflammation in physiology and physiopathology of non-alcoholic fatty liver disease.
FEBS Journal (The Federation of European Biochemical Societies)
10.1111/febs.15877.
(In press).
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Voisin, M;
Shrestha, E;
Rollet, C;
Nikain, CA;
Josefs, T;
Mahé, M;
Barrett, TJ;
... Garabedian, MJ; + view all
(2021)
Inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in mice.
Communications Biology
, 4
(1)
, Article 420. 10.1038/s42003-021-01925-5.
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Waddington, KE;
Robinson, GA;
Rubio-Cuesta, B;
Chrifi-Alaoui, E;
Andreone, S;
Poon, K-S;
Ivanova, I;
... Pineda-Torra, I; + view all
(2021)
LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function.
Proceedings of the National Academy of Sciences of the United States of America
, 118
(21)
, Article e2017394118. 10.1073/pnas.2017394118.
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2020
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Coelewij, L;
Waddington, K;
Robinson, G;
Chocano, E;
McDonnell, T;
Farinha, F;
Peng, J;
... Pineda-Torra, I; + view all
(2020)
Using serum metabolomics analysis to predict sub-clinical atherosclerosis in patients with SLE.
MedRxiv: Cold Spring Harbor, NY, USA.
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Kang, L;
Zhang, X;
Ji, L;
Kou, T;
Smith, SM;
Zhao, B;
Guo, X;
... Hu, X; + view all
(2020)
The colonic macrophage transcription factor RBP-J orchestrates intestinal immunity against bacterial pathogens.
The Journal of Experimental Medicine
, 217
(4)
, Article e20190762. 10.1084/jem.20190762.
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Robinson, GA;
Peng, J;
Dönnes, P;
Coelewij, L;
Naja, M;
Radziszewska, A;
Wincup, C;
... Jury, EC; + view all
(2020)
Disease-associated and patient-specific immune cell signatures in juvenile-onset systemic lupus erythematosus: patient stratification using a machine-learning approach.
The Lancet Rheumatology
, 2
(8)
e485-e496.
10.1016/s2665-9913(20)30168-5.
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Voisin, M;
Gage, M;
Becares, N;
Shrestha, E;
Fisher, EA;
Pineda-Torra, I;
Garabedian, MJ;
(2020)
LXRα phosphorylation in cardiometabolic disease: insight from mouse models.
Endocrinology
, 161
(7)
, Article bqaa089. 10.1210/endocr/bqaa089.
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Waddington, KE;
Papadaki, A;
Coelewij, L;
Adriani, M;
Nytrova, P;
Kubala Havrdova, E;
Fogdell-Hahn, A;
... Jury, EC; + view all
(2020)
Using Serum Metabolomics to Predict Development of Anti-drug Antibodies in Multiple Sclerosis Patients Treated With IFNβ.
Frontiers In Immunology
, 11
, Article 1527. 10.3389/fimmu.2020.01527.
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2019
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Becares, N;
Gage, MC;
Voisin, M;
Shrestha, E;
Martin-Gutierrez, L;
Liang, N;
Louie, R;
... Pineda-Torra, I; + view all
(2019)
Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease.
Cell Reports
, 26
(4)
984-995.e6.
10.1016/j.celrep.2018.12.094.
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Becares, N;
Pineda-Torra, I;
(2019)
Identification of Nuclear Receptor Targets by Chromatin Immunoprecipitation in Fatty Liver.
Lipid-Activated Nuclear Receptors
, 1951
pp. 179-188.
10.1007/978-1-4939-9130-3_14.
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Martin-Gutierrez, L;
Wilton, J;
Robinson, G;
McDonnell, T;
Isenberg, D;
Wincup, C;
Kalea, A;
... Ciurtin, C; + view all
(2019)
Designing a diet interventional study for autoimmune rheumatic disease: asking patients what they think.
Presented at: EULAR: Annual European Congress of Rheumatology, Madrid, Spain.
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Robinson, G;
McDonnell, T;
Wincup, C;
Martin-Gutierrez, L;
Wilton, J;
Kalea, A;
Ciurtin, C;
... Jury, E; + view all
(2019)
Cardiovascular disease in SLE: what do patients think about using diet as a therapeutic?
Presented at: European League Against Rheumatism (EULAR) 2019, Madrid, Spain.
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Robinson, GA;
Mcdonnell, T;
Wincup, C;
Martin-Gutierrez, L;
Wilton, J;
Kalea, AZ;
Ciurtin, C;
... Jury, EC; + view all
(2019)
Diet and lupus: what do the patients think?
Lupus
, 28
(6)
pp. 755-763.
10.1177/0961203319845473.
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2018
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Gage, MC;
Bécares, N;
Louie, R;
Waddington, KE;
Zhang, Y;
Tittanegro, TH;
Rodríguez-Lorenzo, S;
... Pineda-Torra, I; + view all
(2018)
Disrupting LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation.
Proceedings of the National Academy of Sciences of the United States of America
, 115
(28)
E6556-E6565.
10.1073/pnas.1721245115.
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Shrestha, E;
Voisin, M;
Barret, T;
Nishi, H;
Cantor, D;
Hissein, M;
David, G;
... Garabedian, M; + view all
(2018)
Phosphorylation of LXRα impacts atherosclerosis regression by modulating monocyte trafficking.
bioRxiv
10.1101/363366.
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Waddington, Kirsty Elizabeth;
(2018)
Regulation of membrane lipid metabolism and immune cell function by the nuclear receptor LXR.
Doctoral thesis (Ph.D), UCL (University College London).
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2017
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Becares, N;
Gage, M;
Martin-Gutierrez, L;
Pourcet, B;
Louie, R;
Pello, O;
Luong, TV;
... Pineda Torra, I; + view all
(2017)
Changes In LXRα Phosphorylation Promote A Novel Diet-Induced Transcriptome That Alters The Transition From Fatty Liver To Steatohepatitis.
BioRxiv: Cold Spring Harbor, NY, USA.
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Becares Salles, N;
Gage, MC;
Pineda-Torra, I;
(2017)
Post-translational modifications of lipid-activated nuclear receptors: Focus on metabolism.
Endocrinology
, 158
(2)
pp. 213-225.
10.1210/en.2016-1577.
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Gage, M;
Becares, N;
Louie, R;
Waddington, K;
ZHANG, Y;
Tittanegro, T;
Rodriguez-Lorenzo, S;
... Pineda Torra, I; + view all
(2017)
Disrupting myeloid-specific LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation.
bioRxiv: Cold Spring Harbor, NY, USA.
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Robinson, G;
Waddington, KE;
Pineda Torra, I;
Jury, EC;
(2017)
Transcriptional Regulation of T-Cell Lipid Metabolism: Implications for Plasma Membrane Lipid Rafts and T-Cell Function.
Frontiers in Immunology
, 8
, Article 1636. 10.3389/fimmu.2017.01636.
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2016
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Pourcet, B;
Gage, MC;
León, TE;
Waddington, KE;
Pello, OM;
Steffensen, KR;
Castrillo, A;
... Pineda-Torra, I; + view all
(2016)
The nuclear receptor LXR modulates interleukin-18 levels in macrophages through multiple mechanisms.
Scientific Reports
, 6
, Article 25481. 10.1038/srep25481.
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Smith, E;
Croca, S;
Waddington, K;
Sofat, R;
Griffin, M;
Nicolaides, A;
Isenberg, D;
... Jury, EC; + view all
(2016)
Cross-talk between iNKT cells and monocytes triggers an atheroprotective immune response in SLE patients with asymptomatic plaque.
Science Immunology
, 1
(6)
, Article eaah4081. 10.1126/sciimmunol.aah4081.
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2011
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Feig, JE;
Shang, Y;
Rotllan, N;
Vengrenyuk, Y;
Wu, C;
Shamir, R;
Torra, IP;
... Garabedian, MJ; + view all
(2011)
Statins promote the regression of atherosclerosis via activation of the CCR7-dependent emigration pathway in macrophages.
PLOS One
, 6
(12)
, Article e28534. 10.1371/journal.pone.0028534.
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