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Science Forum: Sex differences and sex bias in human circadian and sleep physiology research

Spitschan, Manuel; Santhi, Nayantara; Ahluwalia, Amrita; Fischer, Dorothee; Hunt, Lilian; Karp, Natasha; Lévi, Francis; ... White, Rhiannon; + view all (2022) Science Forum: Sex differences and sex bias in human circadian and sleep physiology research. Elife , 11 , Article e65419. 10.7554/eLife.65419. (In press). Green open access

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Abstract

Growing evidence shows that sex differences impact many facets of human biology. Here we review and discuss the impact of sex on human circadian and sleep physiology, and we uncover a data gap in the field investigating the non-visual effects of light in humans. A virtual workshop on the biomedical implications of sex differences in sleep and circadian physiology then led to the following imperatives for future research: (1) design research to be inclusive and accessible, (2) implement recruitment strategies that lead to a sex-balanced sample, (3) use data visualization to grasp the effect of sex, (4) implement statistical analyses that include sex as a factor and/or perform group analyses by sex, where possible, (5) make participant-level data open and available to facilitate future meta-analytic efforts.

Type: Article
Title: Science Forum: Sex differences and sex bias in human circadian and sleep physiology research
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.7554/eLife.65419
Publisher version: https://doi.org/10.7554/eLife.65419
Language: English
Additional information: © 2022, Spitschan et al. This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Experimental and Translational Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10144182
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