Browse by UCL people
Group by: Type | Date
Number of items: 79.
2019
Ciccarelli, O;
Cohen, JA;
Reingold, SC;
Weinshenker, G;
(2019)
Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders.
Lancet Neurology
, 18
(2)
pp. 185-197.
10.1016/S1474-4422(18)30460-5.
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2018
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Brownlee, WJ;
Miszkiel, KA;
Tur, C;
Barkhof, F;
Miller, DH;
Ciccarelli, O;
(2018)
Inclusion of optic nerve involvement in dissemination in space criteria for multiple sclerosis.
Neurology
, 91
(12)
e1130-e1134.
10.1212/WNL.0000000000006207.
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Castellazzi, G;
Debernard, L;
Melzer, TR;
Dalrymple-Alford, JC;
D'Angelo, E;
Miller, DH;
Wheeler-Kingshott, CAM;
(2018)
Functional connectivity alternations reveal complex mechanisms based on clinical and radiological status in mild relapsing remitting multiple sclerosis.
Frontiers in Neurology
, 9
, Article 690. 10.3389/fneur.2018.00690.
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Gold, J;
Marta, M;
Meier, UC;
Christensen, T;
Miller, D;
Altmann, D;
Holden, D;
... Giovannoni, G; + view all
(2018)
A phase II baseline versus treatment study to determine the efficacy of raltegravir (Isentress) in preventing progression of relapsing remitting multiple sclerosis as determined by gadolinium-enhanced MRI: The INSPIRE study.
Multiple Sclerosis and Related Disorders
, 24
pp. 123-128.
10.1016/j.msard.2018.06.002.
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Miller, DH;
Lublin, FD;
Sormani, MP;
Kappos, L;
Yaldizli, Ö;
Freedman, MS;
Cree, BAC;
... Wolinsky, JS; + view all
(2018)
Brain atrophy and disability worsening in primary progressive multiple sclerosis: Insights from the INFORMS study.
Annals of Clinical and Translational Neurology
, 5
(3)
pp. 346-356.
10.1002/acn3.534.
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Montalban, X;
Gold, R;
Thompson, AJ;
Otero-Romero, S;
Amato, MP;
Chandraratna, D;
Clanet, M;
... Zipp, F; + view all
(2018)
ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis.
European Journal of Neurology
, 25
(2)
pp. 215-237.
10.1111/ene.13536.
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Montalban, X;
Gold, R;
Thompson, AJ;
Otero-Romero, S;
Amato, MP;
Chandraratna, D;
Clanet, M;
... Zipp, F; + view all
(2018)
ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis.
Multiple Sclerosis Journal
, 24
(2)
pp. 96-120.
10.1177/1352458517751049.
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Yaldizli, Ö;
Sethi, V;
Pardini, M;
Tur, C;
Mok, KY;
Muhlert, N;
Liu, Z;
... Chard, DT; + view all
(2018)
Response to the commentary of Yates RL and DeLuca GC on the study: HLA-DRB1*1501 associations with magnetic resonance imaging measures of grey matter pathology in multiple sclerosis.
Multiple Sclerosis and Related Disorders
, 19
pp. 168-170.
10.1016/j.msard.2016.08.006.
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2017
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Brownlee, W;
Altmann, DR;
Alves Da Mota, P;
Swanton, JK;
Miszkeil, KA;
Wheeler-Kingshott, CAM;
Ciccarelli, O;
(2017)
Association of asymptomatic spinal cord lesions and atrophy with disability 5 years after a clinically isolated syndrome.
Multiple Sclerosis Journal
, 23
(5)
pp. 665-674.
10.1177/1352458516663034.
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Brownlee, W;
Hardy, TA;
Fazekas, F;
Miller, DH;
(2017)
Diagnosis of multiple sclerosis: progress and challenges.
The Lancet
, 389
(10076)
pp. 1336-1346.
10.1016/S0140-6736(16)30959-X.
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Cawley, N;
Tur Gomez, C;
Prados Carrasco, F;
Plantone, D;
Kearney, H;
Abdel-Aziz, K;
Ourselin, S;
... Ciccarelli, O; + view all
(2017)
Spinal cord atrophy as a primary outcome measure in phase II trials of progressive multiple sclerosis.
Multiple Sclerosis
10.1177/1352458517709954.
(In press).
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Liechti, MD;
Yiannakas, M;
Budtarad, N;
Toosy, AT;
Yang, X;
Prados Carrasco, F;
Miller, DH;
... Panicker, J; + view all
(2017)
Assessing Changes Within the Lumbosacral Spinal Cord in Neurological Disease: Preliminary Results of a Pilot in Vivo MRI Study.
In:
The ISMRM 25th Annual Meeting & Exhibition.
ISMRM: Honolulu, USA.
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Miller, DH;
Thompson, AJ;
(2017)
Advancing trial design in progressive multiple sclerosis.
Multiple Sclerosis Journal
, 23
(12)
pp. 1571-1572.
10.1177/1352458517729767.
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Samson, RS;
Cardoso, MJ;
Muhlert, N;
Sethi, V;
Yaldizli, Ö;
Ron, MA;
Prados Carrasco, F;
... Chard, DT; + view all
(2017)
Longitudinal outer and inner cortical MTR abnormalities in different MS clinical phenotypes.
In:
Proceedings of the ISMRM 25th Annual Meeting & Exhibition.
International Society for Magnetic Resonance in Medicine (ISMRM): Honululu, HI, USA.
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Schneider, T;
Brownlee, W;
Zhang, H;
Ciccarelli, O;
Miller, DH;
Wheeler-Kingshott, CG;
(2017)
Sensitivity of multi-shell NODDI to multiple sclerosis white matter changes: a pilot study.
Functional Neurology
, 32
(2)
pp. 97-101.
10.11138/FNeur/2017.32.2.097.
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Thompson, A;
Kobelt, G;
Berg, J;
Capsa, D;
Eriksson, J;
Miller, D;
(2017)
New insights into the burden and costs of multiple sclerosis in Europe: Results for the United Kingdom.
Multiple Sclerosis Journal
, 23
(2)
pp. 204-216.
10.1177/1352458517708687.
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Thompson, AJ;
Banwell, BL;
Barkhof, F;
Carroll, WM;
Coetzee, T;
Comi, G;
Correale, J;
... Cohen, JA; + view all
(2017)
Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria.
The Lancet Neurology
, 17
(2)
pp. 162-173.
10.1016/S1474-4422(17)30470-2.
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2016
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Brown, WL;
Pardini, M;
Brownlee, WJ;
Fernando, K;
Samson, R;
Prados Carrasco, F;
Ourselin, S;
... Chard, DT; + view all
(2016)
An abnormal periventricular magnetisation transfer ratio gradient occurs early in multiple sclerosis.
Brain
, 140
(2)
pp. 387-398.
10.1093/brain/aww296.
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Brownlee, WJ;
Miszkiel, KA;
Altmann, DR;
Ciccarelli, O;
Miller, DH;
(2016)
Periventricular lesions and MS diagnostic criteria in young adults with typical clinically isolated syndromes.
Multiple Sclerosis
, 23
(7)
pp. 1031-1034.
10.1177/1352458516667565.
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Brownlee, WJ;
Swanton, JK;
Miszkiel, KA;
Miller, DH;
Ciccarelli, O;
(2016)
Should the symptomatic region be included in dissemination in space in MRI criteria for MS?
NeuroIogy
, 87
(7)
pp. 680-683.
10.1212/WNL.0000000000002975.
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Chard, DT;
Miller, DH;
(2016)
What lies beneath grey matter atrophy in multiple sclerosis?
[Editorial comment].
Brain
, 139
(Pt 1)
pp. 7-10.
10.1093/brain/awv354.
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Chataway, J;
Chandran, S;
Miller, D;
Connick, P;
Giovannoni, G;
Pavitt, S;
Stallard, N;
... Sharrack, B; + view all
(2016)
Recruitment In Multiple Sclerosis Trials: The MS-SMART Experience.
Presented at: 2016 Annual Meeting of the Association of British Neurologists (ABN), Brighton, UK.
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Connick, P;
Miller, D;
Pavitt, S;
Giovannoni, G;
Wheeler-Kingshott, C;
Weir, C;
Stallard, N;
... The MS-SMART Trialists; + view all
(2016)
MS-SMART trial design and recruitment status: a multi-arm phase IIB randomised double blind placebo-controlled clinical trial comparing the efficacy of three repositioned neuroprotective drugs in secondary progressive multiple sclerosis.
Presented at: 32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), London, UK.
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Cortese, R;
Magnollay, L;
De Angelis, F;
Prados Carrasco, F;
Grussu, F;
Tur Gomez, C;
Yiannakas, M;
... Ciccarelli, O; + view all
(2016)
No differences in spinal cord DTI abnormalilties between neuromyelitis optica spectrum disorder and multiple sclerosis.
In:
(Proceedings) ECTRIMS 2016: 32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis, 14 - 17 September 2016, London, UK.
European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS): Basel, Switzerland.
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De Angelis, F;
Cameron, J;
Connick, P;
Miller, DH;
Pavitt, S;
Giovannoni, G;
Wheeler-Kingshott, C;
... for MS-SMART trialists; + view all
(2016)
Optical coherence tomography in secondary progressive multiple sclerosis: a baseline data report from the MS-SMART trial.
Presented at: 32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), London, UK.
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Gold, R;
Arnold, DL;
Bar-Or, A;
Hutchinson, M;
Kappos, L;
Havrdova, E;
MacManus, DG;
... Phillips, TJ; + view all
(2016)
Long-term effects of delayed-release dimethyl fumarate in multiple sclerosis: Interim analysis of ENDORSE, a randomized extension study.
Multiple Sclerosis Journal
, 23
(2)
pp. 253-265.
10.1177/1352458516649037.
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Kapoor, R;
Raftopoulos, R;
Altmann, DR;
Miller, DH;
Hickman, SJ;
(2016)
Phenytoin for neuroprotection: Authors' reply.
The Lancet Neurology
, 15
(9)
pp. 902-903.
10.1016/S1474-4422(16)30094-1.
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Kapoor, R;
Raftopoulos, R;
Hickman, SJ;
Toosy, A;
Sharrack, B;
Shahrukh, M;
Paling, D;
... Miller, DH; + view all
(2016)
Phenytoin for neuroprotection in acute optic neuritis: a randomised, placebo-controlled, phase 2 trial.
The Lancet Neurology
10.1016/S1474-4422(16)00004-1.
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Kearney, H;
Miszkiel, KA;
Yiannakas, MC;
Altmann, DR;
Ciccarelli, O;
Miller, DH;
(2016)
Grey matter involvement by focal cervical spinal cord lesions is associated with progressive multiple sclerosis.
Multiple Sclerosis Journal
, 22
(7)
pp. 910-920.
10.1177/1352458515604905.
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Lublin, F;
Miller, DH;
Freedman, MS;
Cree, BA;
Wolinsky, JS;
Weiner, H;
Lubetzki, C;
... INFORMS study investigators, .; + view all
(2016)
Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trial.
The Lancet
, 387
(10023)
pp. 1075-1084.
10.1016/S0140-6736(15)01314-8.
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Pardini, M;
Sudre, CH;
Prados, F;
Yaldizli, Ö;
Sethi, V;
Muhlert, N;
Samson, RS;
... Chard, DT; + view all
(2016)
Relationship of grey and white matter abnormalities with distance from the surface of the brain in multiple sclerosis.
Journal of Neurology, Neurosurgery and Psychiatry
, 87
(11)
pp. 1212-1217.
10.1136/jnnp-2016-313979.
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Prados Carrasco, F;
Cardoso, MJ;
Yiannakas, MC;
Hoy, LR;
Tebaldi, E;
Kearney, H;
Liechti, MD;
... Ourselin, S; + view all
(2016)
Fully automated grey and white matter spinal cord segmentation.
Scientific Reports
, 6
, Article 36151. 10.1038/srep36151.
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Prados Carrasco, F;
Solanky, BS;
Alves da Mota, P;
Cardoso, MJ;
Brownlee, WJ;
Riemer, F;
Miller, DH;
... Wheeler-Kingshott, CAM; + view all
(2016)
Regional variation of total sodium concentration in the healthy human brain.
Presented at: International Society for Magnetic Resonance in Medicine (ISMRM) 24th Scientific Meeting and Exhibition, Singapore.
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Prados Carrasco, F;
Solanky, BS;
Alves Da Mota, P;
Cardoso, MJ;
Brownlee, WJ;
Riemer, F;
Miller, DH;
... Ourselin, S; + view all
(2016)
Automatic sodium maps reconstruction using PatchMatch algorithm for phantom detection.
Presented at: International Society for Magnetic Resonance in Medicine (ISMRM) 24th Scientific Meeting and Exhibition, Singapore.
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Prados Carrasco, F;
Yiannakas, MC;
Cardoso, MJ;
Grussu, F;
De Angelis, F;
Plantone, D;
Miller, DH;
... Ourselin, S; + view all
(2016)
Computing spinal cord atrophy using the Boundary Shift Integral: a more powerful outcome measure for clinical trials?
In:
ECTRIMS Online Library.
(pp. P1605).
European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS): Basel, Switzerland.
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Prados Carrasco, F;
Yiannakas, MC;
Cardoso, MJ;
Grussu, F;
De Angelis, F;
Plantone, D;
Miller, DH;
... Ourselin, S; + view all
(2016)
Atrophy computation in the spinal cord using the Boundary Shift Integral.
In:
Proceedings of the 24th Scientific Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM).
International Society for Magnetic Resonance in Medicine (ISMRM): Singapore.
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Samson, RS;
Brownlee, WJ;
Cardoso, MJ;
Brown, WJL;
Pardini, M;
Prados Carrasco, F;
Ourselin, S;
... Chard, DT; + view all
(2016)
Outer and inner cortical MTR abnormalities in clinically isolated syndromes.
Presented at: ECTRIMS 2016: 32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis, London, UK.
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Samson, RS;
Cardoso, MJ;
Brownlee, WJ;
Brown, WJL;
Pardini, M;
Ourselin, S;
Wheeler-Kingshott, CAM;
(2016)
Outer and inner cortical MTR abnormalities observed in clinically isolated syndromes.
Presented at: International Society for Magnetic Resonance in Medicine (ISMRM) 24th Annual Meeting & Exhibition 2016, Singapore, Malaysia.
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Thompson, AJ;
Meijer, KA;
Muhlert, N;
Sethi, V;
Ron, MA;
Miller, DH;
Chard, D;
... Cercignani, M; + view all
(2016)
White matter tract abnormalities are associated with cognitive dysfunction and secondary progressive multiple sclerosis.
Multiple Sclerosis Journal
, 22
(11)
pp. 1429-1437.
10.1177/1352458515622694.
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Tur, C;
Eshaghi, A;
Jenkins, TM;
Prados, F;
Clayden, JD;
Ourselin, S;
Altmann, DR;
... Toosy, AT; + view all
(2016)
Longitudinal changes in structural cortical networks after clinically isolated syndrome.
Presented at: 22nd Annual Meeting of the Organization for Human Brain Mapping, Geneva, Switzerland.
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Tur, C;
Eshaghi, A;
Jenkins, TM;
Prados, F;
Clayden, JD;
Ourselin, S;
Altmann, DR;
... Toosy, AT; + view all
(2016)
Longitudinal changes in structural cortical networks after clinically isolated syndrome.
European Journal of Neurology
, 23
(S2)
, Article O1122. 10.1111/ene.13091.
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van de Pavert, SH;
Muhlert, N;
Sethi, V;
Wheeler-Kingshott, CA;
Ridgway, GR;
Geurts, JJ;
Ron, M;
... Ciccarelli, O; + view all
(2016)
DIR-visible grey matter lesions and atrophy in multiple sclerosis: partners in crime?
Journal of Neurology, Neurosurgery and Psychiatry
, 87
(5)
pp. 461-467.
10.1136/jnnp-2014-310142.
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Yaldizli, Ö;
Pardini, M;
Sethi, V;
Muhlert, N;
Liu, Z;
Tozer, DJ;
Samson, RS;
... Chard, DT; + view all
(2016)
Characteristics of lesional and extra-lesional cortical grey matter in relapsing-remitting and secondary progressive multiple sclerosis: A magnetisation transfer and diffusion tensor imaging study.
Multiple Sclerosis Journal
, 22
(2)
pp. 150-159.
10.1177/1352458515586085.
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Yaldizli, Ö;
Sethi, V;
Pardini, M;
Tur, C;
Mok, KY;
Muhlert, N;
Liu, Z;
... Chard, DT; + view all
(2016)
HLA-DRB∗1501 associations with magnetic resonance imaging measures of grey matter pathology in multiple sclerosis.
Multiple Sclerosis and Related Disorders
, 7
pp. 47-52.
10.1016/j.msard.2016.03.003.
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Yiannakas, M;
Grussu, F;
Polymnia, L;
Prados Carrasco, F;
Samson, R;
Battiston, M;
Altmann, D;
... Wheeler-Kingshott, C; + view all
(2016)
Reduced field-of-view diffusion-weighted imaging of the lumbosacral enlargement: a pilot in vivo study of the healthy spinal cord at 3T.
PLoS One
, 11
(10)
, Article e0164890. 10.1371/journal.pone.0164890.
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Yiannakas, MC;
Mustafa, AM;
De Leener, B;
Kearney, H;
Tur, C;
Altmann, DR;
De Angelis, F;
... Gandini Wheeler-Kingshott, CAM; + view all
(2016)
Fully automated segmentation of the cervical cord from T1-weighted MRI using PropSeg: Application to multiple sclerosis.
NeuroImage: Clinical
, 10
pp. 71-77.
10.1016/j.nicl.2015.11.001.
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2015
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Alla, S;
Pearson, JF;
Taylor, BV;
Roxburgh, R;
Clarke, G;
Miller, DH;
Richardson, A;
... Mason, DF; + view all
(2015)
An investigation of the relationship between latitude and multiple sclerosis severity in New Zealand.
[Letter].
Multiple Sclerosis Journal
10.1177/1352458515605909.
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Bodini, B;
Chard, D;
Altmann, DR;
Tozer, D;
Miller, DH;
Thompson, AJ;
Wheeler-Kingshott, CAM;
(2015)
White and grey matter damage in primary-progressive MS: the chicken or the egg?
Neurology
, 86
(2)
pp. 170-176.
10.1212/WNL.0000000000002237.
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Brownlee, W;
Swanton, JK;
Altmann, DR;
Ciccarelli, O;
Miller, DH;
(2015)
Earlier and more frequent diagnosis of multiple sclerosis using the McDonald criteria.
Journal of Neurology, Neurosurgery and Psychiatry
, 86
(5)
pp. 584-585.
10.1136/jnnp-2014-308675.
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Cawley, N;
Solanky, BS;
Muhlert, N;
Tur, C;
Edden, RA;
Wheeler-Kingshott, CA;
Miller, DH;
... Ciccarelli, O; + view all
(2015)
Reduced gamma-aminobutyric acid concentration is associated with physical disability in progressive multiple sclerosis.
Brain
, 138
(9)
pp. 2584-2595.
10.1093/brain/awv209.
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Liu, Z;
Pardini, M;
Yaldizli, Ö;
Sethi, V;
Muhlert, N;
Wheeler-Kingshott, CA;
Samson, RS;
... Chard, DT; + view all
(2015)
Magnetization transfer ratio measures in normal-appearing white matter show periventricular gradient abnormalities in multiple sclerosis.
Brain
, 138
(5)
pp. 1239-1246.
10.1093/brain/awv065.
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Magnollay, L;
De Angelis, F;
Wottschel, V;
Toosy, A;
Tur, C;
Yiannakas, M;
Cortese, R;
... Ciccarelli, O; + view all
(2015)
Can optic nerve MTR and OCT distinguish between multiple sclerosis and neuromyelitis optica?
Multiple Sclerosis Journal
, 21
(S11)
pp. 346-347.
10.1177/1352458515602642.
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Mallik, S;
Muhlert, N;
Samson, RS;
Sethi, V;
Wheeler-Kingshott, CA;
Miller, DH;
Chard, DT;
(2015)
Regional patterns of grey matter atrophy and magnetisation transfer ratio abnormalities in multiple sclerosis clinical subgroups: A voxel-based analysis study.
Mult Scler
, 21
(4)
423 - 432.
10.1177/1352458514546513.
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Muhlert, N;
Sethi, V;
Cipolotti, L;
Haroon, H;
Parker, GJ;
Yousry, T;
Wheeler-Kingshott, C;
... Chard, D; + view all
(2015)
The grey matter correlates of impaired decision-making in multiple sclerosis.
Journal of Neurology, Neurosurgery & Psychiatry
, 86
(5)
pp. 530-536.
10.1136/jnnp-2014-308169.
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Sethi, V;
Yousry, T;
Muhlert, N;
Tozer, DJ;
Altmann, D;
Ron, M;
Wheeler-Kingshott, CAM;
... Chard, DT; + view all
(2015)
A longitudinal study of cortical grey matter lesion subtypes in relapse-onset multiple sclerosis.
Journal of Neurology, Neurosurgery and Psychiatry
, 87
pp. 750-753.
10.1136/jnnp-2015-311102.
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Ugorji, CO;
Samson, RS;
Liechti, MD;
Panicker, JN;
Miller, DH;
Wheeler-Kingshott, CA;
Yiannakas, MC;
(2015)
Grey and White Matter Magnetisation Transfer Ratio Measurements in the Lumbosacral Enlargement: A Pilot In Vivo Study at 3T.
PLoS One
, 10
(7)
, Article e0134495. 10.1371/journal.pone.0134495.
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Wottschel, V;
Alexander, DC;
Kwok, PP;
Chard, DT;
Thompson, AJ;
Miller, DH;
Ciccarelli, O;
(2015)
Predicting outcome in clinically isolated syndrome using machine learning.
NeuroImage
, 7
pp. 281-287.
10.1016/j.nicl.2014.11.021.
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2014
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Bodini, B;
Cercignani, M;
Toosy, A;
Stefano, ND;
Miller, DH;
Thompson, AJ;
Ciccarelli, O;
(2014)
A novel approach with "skeletonised MTR" measures tract-specific microstructural changes in early primary-progressive MS.
Human Brain Mapping
, 35
(2)
pp. 723-733.
10.1002/hbm.22196.
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Kearney, H;
Rocca, M;
Valsasina, P;
Balk, L;
Sastre-Garriga, J;
Reinhardt, J;
Ruggieri, S;
... Chard, D; + view all
(2014)
Magnetic resonance imaging correlates of physical disability in relapse onset multiple sclerosis of long disease duration.
Mult Scler
, 20
(1)
pp. 72-80.
10.1177/1352458513492245.
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Mallik, S;
Samson, RS;
Wheeler-Kingshott, CA;
Miller, DH;
(2014)
Imaging outcomes for trials of remyelination in multiple sclerosis.
J Neurol Neurosurg Psychiatry
, 85
(12)
1396 - 1404.
10.1136/jnnp-2014-307650.
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Muhlert, N;
Atzori, M;
De Vita, E;
Thomas, DL;
Samson, RS;
Wheeler-Kingshott, CA;
Geurts, JJ;
... Ciccarelli, O; + view all
(2014)
Memory in multiple sclerosis is linked to glutamate concentration in grey matter regions.
Journal of Neurology, Neurosurgery and Psychiatry
, 85
(8)
pp. 833-839.
10.1136/jnnp-2013-306662.
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Toosy, AT;
Mason, DF;
Miller, DH;
(2014)
Optic neuritis.
The Lancet Neurology
, 13
(1)
pp. 83-99.
10.1016/S1474-4422(13)70259-X.
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Tur, C;
Wheeler-Kingshott, CA;
Altmann, DR;
Miller, DH;
Thompson, AJ;
Ciccarelli, O;
(2014)
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Low Myo‐inositol indicating astrocytic damage in a case series of neuromyelitis optica.
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MRI Acquisition and Analysis Protocol for In Vivo Intraorbital Optic Nerve Segmentation at 3T.
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Interferon beta in multiple sclerosis: experience in a British specialist multiple sclerosis centre.
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A controlled trial of natalizumab for relapsing multiple sclerosis.
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Brex, P.A.;
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A longitudinal study of abnormalities on MRI and disability from multiple sclerosis.
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