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Article

Abeyakoon, O; Latifoltojar, A; Gong, F; Papoutsaki, M-V; Chowdhury, R; Glaser, M; Jeraj, H; ... Punwani, S; + view all (2019) Hyperpolarised 13C MRI: a new horizon for non-invasive diagnosis of aggressive breast cancer. BJR case reports , 5 (3) , Article 20190026. 10.1259/bjrcr.20190026. Green open access
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Adeleke, S; Latifoltojar, A; Sidhu, H; Galazi, M; Shah, TT; Clemente, J; Davda, R; ... Punwani, S; + view all (2019) Localising occult prostate cancer metastasis with advanced imaging techniques (LOCATE trial): a prospective cohort, observational diagnostic accuracy trial investigating whole-body magnetic resonance imaging in radio-recurrent prostate cancer. BMC Medical Imaging , 19 , Article 90. 10.1186/s12880-019-0380-y. Green open access
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Al-Mossawi, H; Yager, N; Taylor, CA; Lau, E; Danielli, S; de Wit, J; Gilchrist, J; ... Fairfax, BP; + view all (2019) Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele. Nature Communications , 10 , Article 4575. 10.1038/s41467-019-12393-1. Green open access
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Alifrangis, C; McGovern, U; Freeman, A; Powles, T; Linch, M; (2019) Molecular and histopathology directed therapy for advanced bladder cancer. Nature Reviews Urology , 16 (8) pp. 465-483. 10.1038/s41585-019-0208-0. Green open access
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Attard, G; Conteduca, V; Wetterskog, D; (2019) A multimodal approach to outcome prediction in metastatic castration-resistant prostate cancer by integrating functional imaging and plasma DNA analysis. JCO Precision Oncology 10.1200/PO.18.00302. (In press). Green open access
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Attard, G; Jayaram, A; Wingate, A; Wetterskog, K; (2019) Plasma Androgen Receptor Copy Number Status at Emergence of Metastatic Castration-Resistant Prostate Cancer: A Pooled Multicohort Analysis. JCO Precision Oncology , 3 10.1200/PO.19.00123. Green open access
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Attard, G; Wetterskog, D; Jayaram, A; Wingate, A; (2019) Plasma AR status and cabazitaxel in heavily-treated metastatic castration-resistant prostate cancer. European Journal of Cancer , 116 pp. 158-168. 10.1016/j.ejca.2019.05.007. Green open access
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Barber, PR; Weitsman, G; Lawler, K; Barrett, J; Rowley, M; Rodriguez-Justo, M; Fisher, D; ... Ng, T; + view all (2019) HER2-HER3 heterodimer quantification by FRET-FLIM and patient subclass analysis of the COIN colorectal trial. JNCI: Journal of the National Cancer Institute 10.1093/jnci/djz231. (In press). Green open access
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Beaton, L; Tregidgo, HFJ; Znati, SA; Forsyth, S; Clarkson, MJ; Bandula, S; Chouhan, M; ... Sharma, RA; + view all (2019) VEROnA Protocol: A Pilot, Open-Label, Single-Arm, Phase 0, Window-of-Opportunity Study of Vandetanib-Eluting Radiopaque Embolic Beads (BTG-002814) in Patients With Resectable Liver Malignancies. JMIR Research Protocols , 8 (10) , Article e13696. 10.2196/13696. Green open access
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Beedham, W; Peck, G; Richardson, S; Tsang, K; Fertleman, M; Shipway, D; (2019) Head injury in the elderly – an overview for the physician. Clinical Medicine , 19 (2) pp. 177-184. 10.7861/clinmedicine.19-2-177. Green open access
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Bentham, RB; Bryson, K; Szabadkai, G; (2019) Biclustering Analysis of Co-regulation Patterns in Nuclear-Encoded Mitochondrial Genes and Metabolic Pathways. Cancer Metabolism , 1928 pp. 469-478. 10.1007/978-1-4939-9027-6_24. Green open access
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Bi, WL; Hosny, A; Schabath, MB; Giger, ML; Birkbak, NJ; Mehrtash, A; Allison, T; ... Aerts, HJWL; + view all (2019) Artificial intelligence in cancer imaging: Clinical challenges and applications. CA: A Cancer Journal for Clinicians , 69 (2) pp. 127-157. 10.3322/caac.21552. Green open access
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Bilanges, B; Posor, Y; Vanhaesebroeck, B; (2019) PI3K isoforms in cell signalling and vesicle trafficking. Nature Reviews Molecular Cell Biology , 20 pp. 515-534. 10.1038/s41580-019-0129-z. Green open access
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Biswas, D; Birkbak, NJ; Rosenthal, R; Hiley, CT; Lim, EL; Papp, K; Boeing, S; ... TRACERx Consortium; + view all (2019) A clonal expression biomarker associates with lung cancer mortality. Nature Medicine , 25 pp. 1540-1548. 10.1038/s41591-019-0595-z. Green open access
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Black, JR; Goldin, RD; Foxton, M; Marafioti, T; Akarca, AU; Pria, AD; Brock, C; ... Pinato, DJ; + view all (2019) PD-L1 expressing granulomatous reaction as an on-target mechanism of steroid-refractory immune hepatotoxicity. Immunotherapy , 11 (7) pp. 585-590. 10.2217/imt-2018-0187. Green open access
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Budczies, J; Allgäuer, M; Litchfield, K; Rempel, E; Christopoulos, P; Kazdal, D; Endris, V; ... Stenzinger, A; + view all (2019) Optimizing panel-based tumor mutational burden (TMB) measurement. Annals of Oncology , 30 (9) pp. 1496-1506. 10.1093/annonc/mdz205. Green open access
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Cailleau, T; Adams, LR; Arora, N; Kang, G-D; Masterson, L; Patel, N; Hartley, JA; ... Howard, PW; + view all (2019) Potentiation of PBD Dimers by Lipophilicity Manipulation. Current Topics in Medicinal Chemistry , 19 (9) pp. 741-752. 10.2174/1568026619666190401112517. Green open access
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Chambers, P; Jani, Y; Wei, L; Kipps, E; Forster, MD; Wong, ICK; (2019) Patient Factors and their Impact on Neutropenic Events: A Systematic review and meta-analysis. Supportive Care in Cancer , 27 (7) pp. 2413-2424. 10.1007/s00520-019-04773-6. Green open access
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Chan, TA; Yarchoan, M; Jaffee, E; Swanton, C; Quezada, SA; Stenzinger, A; Peters, S; (2019) Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic. Annals of Oncology , 30 (1) pp. 44-56. 10.1093/annonc/mdy495. Green open access
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Chemi, F; Rothwell, DG; McGranahan, N; Gulati, S; Abbosh, C; Pearce, SP; Zhou, C; ... TRACERx Consortium, .; + view all (2019) Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse. Nature Medicine , 25 pp. 1534-1539. 10.1038/s41591-019-0593-1. Green open access
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Chen, X; Zhabyeyev, P; Azad, AK; Wang, W; Minerath, RA; DesAulniers, J; Grueter, CE; ... Oudit, GY; + view all (2019) Endothelial and cardiomyocyte PI3Kβ divergently regulate cardiac remodelling in response to ischaemic injury. Cardiovascular Research , 115 (8) pp. 1343-1356. 10.1093/cvr/cvy298. Green open access
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Chung, HC; Arkenau, H-T; Lee, J; Rha, SY; Oh, D-Y; Wyrwicz, L; Kang, Y-K; ... Safran, H; + view all (2019) Avelumab (anti-PD-L1) as first-line switch-maintenance or second-line therapy in patients with advanced gastric or gastroesophageal junction cancer: phase 1b results from the JAVELIN Solid Tumor trial. Journal for ImmunoTherapy of Cancer , 7 , Article 30. 10.1186/s40425-019-0508-1. Green open access
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Clarke, NW; Ali, A; Ingleby, FC; Hoyle, A; Amos, CL; Attard, G; Brawley, CD; ... James, ND; + view all (2019) Addition of docetaxel to hormonal therapy in low- and high-burden metastatic hormone sensitive prostate cancer: long-term survival results from the STAMPEDE trial. Annals of Oncology 10.1093/annonc/mdz396. (In press). Green open access
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Conteduca, V; Jayaram, A; Romero-Laorden, N; Wetterskog, D; Salvi, S; Gurioli, G; Scarpi, E; ... de Giorgi, U; + view all (2019) Plasma Androgen Receptor and Docetaxel for Metastatic Castration-resistant Prostate Cancer. European Urology 10.1016/j.eururo.2018.09.049. (In press). Green open access
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Coombes, C; Page, K; Salari, R; Hastings, RK; Armstrong, AC; Ahmed, S; Ali, S; ... Shaw, JA; + view all (2019) Personalized detection of circulating tumor DNA antedates breast cancer metastatic recurrence. Clinical Cancer Research , 25 (14) pp. 4255-4263. 10.1158/1078-0432.CCR-18-3663. Green open access
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Crowley, C; Butler, C; Camilli, C; Hynds, R; Kolluri, KK; Janes, SM; De Coppi, P; (2019) Non-invasive longitudinal bioluminescence imaging of human mesoangioblasts in bioengineered esophagi. Tissue Engineering Part C: Methods , 25 (2) pp. 103-113. 10.1089/ten.TEC.2018.0351. Green open access
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de Bono, JS; Concin, N; Hong, DS; Thistlethwaite, FC; Machiels, J-P; Arkenau, H-T; Plummer, R; ... Lassen, U; + view all (2019) Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial. Lancet Oncology , 20 (3) pp. 383-393. 10.1016/S1470-2045(18)30859-3. Green open access
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Dillon, MT; Grove, L; Newbold, KL; Shaw, H; Brown, NF; Mendell, J; Chen, S; ... Harrington, KJ; + view all (2019) Patritumab with Cetuximab plus Platinum-Containing Therapy in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: An Open-Label, Phase Ib Study. Clinical Cancer Research , 25 (2) pp. 487-495. 10.1158/1078-0432.CCR-18-1539. Green open access
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Evans, R; Flores-Borja, F; Nassiri, S; Miranda, E; Lawler, K; Grigoriadis, A; Monypenny, J; ... Ng, T; + view all (2019) Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer. Cell Reports , 27 (7) 1967-1978.e4. 10.1016/j.celrep.2019.04.076. Green open access
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Evans, TRJ; Dean, E; Molife, LR; Lopez, J; Ranson, M; El-Khouly, F; Zubairi, I; ... Kristeleit, R; + view all (2019) Phase 1 dose-finding and pharmacokinetic study of eribulin-liposomal formulation in patients with solid tumours. British Journal of Cancer , 120 pp. 379-386. 10.1038/s41416-019-0377-x. Green open access
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Forster, MD; Dillon, MT; Kocsis, J; Remenár, É; Pajkos, G; Rolland, F; Greenberg, J; (2019) Patritumab or placebo, with cetuximab plus platinum therapy in recurrent or metastatic squamous cell carcinoma of the head and neck: A randomised phase II study. European Journal of Cancer , 123 pp. 36-47. 10.1016/j.ejca.2019.08.017. Green open access
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Foxall, E; Staszowska, A; Hirvonen, LM; Georgouli, M; Ciccioli, M; Rimmer, A; Williams, L; ... Wells, CM; + view all (2019) PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells. Cell Reports , 29 (11) 3385-3393.e6. 10.1016/j.celrep.2019.11.016. Green open access
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Frizziero, M; Wang, X; Chakrabarty, B; Childs, A; Luong, TV; Walter, T; Khan, MS; ... McNamara, MG; + view all (2019) Retrospective study on mixed neuroendocrine non-neuroendocrine neoplasms from five European centres. World Journal of Gastroenterology , 25 (39) pp. 5991-6005. 10.3748/wjg.v25.i39.5991. Green open access
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Golan, T; Hammel, P; Reni, M; Van Cutsem, E; Macarulla, T; Hall, MJ; Park, J-O; ... Kindler, HL; + view all (2019) Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer. The New England Journal of Medicine , 381 pp. 317-327. 10.1056/NEJMoa1903387. Green open access
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González-Billalabeitia, E; Conteduca, V; Wetterskog, D; Jayaram, A; Attard, G; (2019) Circulating tumor DNA in advanced prostate cancer: transitioning from discovery to a clinically implemented test. Prostate Cancer and Prostatic Diseases , 22 pp. 195-205. 10.1038/s41391-018-0098-x. Green open access
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Greenwood, HE; McCormick, PN; Gendron, T; Glaser, M; Pereira, R; Maddocks, ODK; Sander, K; ... Witney, TH; + view all (2019) Measurement of Tumor Antioxidant Capacity and Prediction of Chemotherapy Resistance in Preclinical Models of Ovarian Cancer by Positron Emission Tomography. Clinical Cancer Research , 25 (8) pp. 2471-2482. 10.1158/1078-0432.CCR-18-3423. Green open access
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Hamilton, N; Hynds, R; Gowers, K; Tait, A; Butler, C; Hopper, C; Burns, A; ... Janes, SM; + view all (2019) Using a 3D collagen matrix to deliver respiratory progenitor cells to decellularized trachea in vivo. Tissue Engineering Part C: Methods , 25 (2) pp. 93-102. 10.1089/ten.TEC.2018.0241. Green open access
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Hammel, P; Kindler, HL; Reni, M; Van Cutsem, E; Macarulla, T; Hall, MJ; Park, JO; ... Golan, T; + view all (2019) Health-related quality of life in patients with a germline BRCA mutation and metastatic pancreatic cancer receiving maintenance olaparib. Annals of Oncology 10.1093/annonc/mdz406. (In press). Green open access
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Han, G; Berhane, S; Toyoda, H; Bettinger, D; Elshaarawy, O; Chan, AWH; Kirstein, M; ... Johnson, PJ; + view all (2019) Prediction of Survival Among Patients Receiving Transarterial Chemoembolization for Hepatocellular Carcinoma: A Response-Based Approach. Hepatology 10.1002/hep.31022. (In press). Green open access
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Handle, F; Prekovic, S; Helsen, C; Van den Broeck, T; Smeets, E; Moris, L; Eerlings, R; ... Claessens, F; + view all (2019) Drivers of AR indifferent anti-androgen resistance in prostate cancer cells. Scientific Reports , 9 , Article 137. 10.1038/s41598-019-50220-1. Green open access
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Hoyle, AP; Ali, A; James, ND; Cook, A; Parker, CC; de Bono, JS; Attard, G; ... STAMPEDE Investigators; + view all (2019) Abiraterone in "High-" and "Low-risk" Metastatic Hormone-sensitive Prostate Cancer. European Urology , 76 (6) pp. 719-728. 10.1016/j.eururo.2019.08.006. Green open access
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Hu, X; Fujimoto, J; Ying, L; Fukuoka, J; Ashizawa, K; Sun, W; Reuben, A; ... Zhang, J; + view all (2019) Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma. Nature Communications , 10 , Article 2978. 10.1038/s41467-019-10877-8. Green open access
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Ilson, DH; Tabernero, J; Prokharau, A; Arkenau, H-T; Ghidini, M; Fujitani, K; Van Cutsem, E; ... Shitara, K; + view all (2019) Efficacy and Safety of Trifluridine/Tipiracil Treatment in Patients With Metastatic Gastric Cancer Who Had Undergone Gastrectomy: Subgroup Analyses of a Randomized Clinical Trial. JAMA Oncology , 6 (1) , Article e193531.. 10.1001/jamaoncol.2019.3531. Green open access
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Jones, GG; Del Río, IB; Sari, S; Sekerim, A; Young, LC; Hartig, N; Areso Zubiaur, I; ... Rodriguez-Viciana, P; + view all (2019) SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers. Nature Communications , 10 (1) , Article 2532. 10.1038/s41467-019-10367-x. Green open access
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Jones, RL; Ratain, MJ; O'Dwyer, PJ; Siu, LL; Jassem, J; Medioni, J; DeJonge, M; ... Schwartz, G; + view all (2019) Phase II randomised discontinuation trial of brivanib in patients with advanced solid tumours. European Journal of Cancer , 120 pp. 132-139. 10.1016/j.ejca.2019.07.024. Green open access
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Jones, RP; Psarelli, E-E; Jackson, R; Ghaneh, P; Halloran, CM; Palmer, DH; Campbell, F; ... European Study Group for Pancreatic Cancer, .; + view all (2019) Patterns of Recurrence After Resection of Pancreatic Ductal Adenocarcinoma: A Secondary Analysis of the ESPAC-4 Randomized Adjuvant Chemotherapy Trial. JAMA Surgery 10.1001/jamasurg.2019.3337. (In press).

Joshi, K; Robert de Massy, M; Ismail, M; Reading, JL; Uddin, I; Woolston, A; Hatipoglu, E; ... Chain, B; + view all (2019) Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer. Nature Medicine , 25 pp. 1549-1559. 10.1038/s41591-019-0592-2. Green open access
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Kidd, AC; Skrzypski, M; Jamal-Hanjani, M; Blyth, KG; (2019) Cancer cachexia in thoracic malignancy: a narrative review. Current Opinion in Supportive and Palliative Care , 13 (4) pp. 316-322. 10.1097/SPC.0000000000000465. Green open access
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Kim, RD; Sarker, D; Meyer, T; Yau, T; Macarulla, T; Park, J-W; Choo, SP; ... Kang, Y-K; + view all (2019) First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant Fibroblast Growth Factor 19 Signaling as a Driver Event in Hepatocellular Carcinoma. Cancer Discovery , 9 (12) pp. 1696-1707. 10.1158/2159-8290.CD-19-0555. Green open access
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Kleftogiannis, D; Punta, M; Jayaram, A; Sandhu, S; Wong, SQ; Gasi Tandefelt, D; Conteduca, V; ... Lise, S; + view all (2019) Identification of single nucleotide variants using position-specific error estimation in deep sequencing data. BMC Med Genomics , 12 (1) , Article 115. 10.1186/s12920-019-0557-9. Green open access
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Kopetz, S; Grothey, A; Yaeger, R; Van Cutsem, E; Desai, J; Yoshino, T; Wasan, H; ... Tabernero, J; + view all (2019) Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer. The New England Journal of Medicine , 381 (17) pp. 1632-1643. 10.1056/NEJMoa1908075. Green open access
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Kristeleit, RS; Oaknin, A; Ray-Coquard, I; Leary, A; Balmaña, J; Drew, Y; Oza, AM; ... McNeish, IA; + view all (2019) Antitumor activity of the poly(ADP-ribose) polymerase inhibitor rucaparib as monotherapy in patients with platinum-sensitive, relapsed, BRCA-mutated, high-grade ovarian cancer, and an update on safety. International Journal of Gynecological Cancer , 29 (9) pp. 1396-1404. 10.1136/ijgc-2019-000623. Green open access
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Lechner, M; Breeze, CE; O'Mahony, JF; Masterson, L; (2019) Early detection of HPV-associated oropharyngeal cancer. [Letter]. Lancet , 393 (10186) p. 2123. 10.1016/S0140-6736(19)30227-2. Green open access
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Lechner, M; Jones, OS; Breeze, CE; Gilson, R; (2019) Gender-neutral HPV vaccination in the UK, rising male oropharyngeal cancer rates, and lack of HPV awareness. [Letter]. Lancet Infectious Diseases , 19 (2) pp. 131-132. 10.1016/S1473-3099(18)30802-8. Green open access
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Lee, DDH; Petris, A; Hynds, RE; O'Callaghan, C; (2019) Ciliated Epithelial Cell Differentiation at Air-Liquid Interface Using Commercially Available Culture Media. Methods in Molecular Biology , 2109 pp. 275-291. 10.1007/7651_2019_269. Green open access
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Lee, SM; Upadhyay, S; Lewanski, C; Falk, S; Skailes, G; Woll, PJ; Hatton, M; ... Hackshaw, A; + view all (2019) The clinical role of VeriStrat testing in patients with advanced non-small cell lung cancer considered unfit for first-line platinum-based chemotherapy. European Journal of Cancer , 120 pp. 86-96. 10.1016/j.ejca.2019.07.025. Green open access
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Lin, CC; Arkenau, HT; Lu, S; Sachdev, J; de Castro Carpeño, J; Mita, M; Dziadziuszko, R; ... Weiss, GJ; + view all (2019) A phase 1, open-label, dose-escalation trial of oral TSR-011 in patients with advanced solid tumours and lymphomas. British Journal of Cancer , 121 pp. 131-138. 10.1038/s41416-019-0503-9. Green open access
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Loveday, C; Sud, A; Litchfield, K; Levy, M; Holroyd, A; Broderick, P; Kote-Jarai, Z; ... Turnbull, C; + view all (2019) Runs of homozygosity and testicular cancer risk. Andrology , 7 (4) pp. 555-564. 10.1111/andr.12667. Green open access
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Luxton, HJ; Simpson, BS; Mills, IG; Brindle, NR; Ahmed, Z; Stavrinides, V; Heavey, S; ... Whitaker, HC; + view all (2019) The Oncogene Metadherin Interacts with the Known Splicing Proteins YTHDC1, Sam68 and T-STAR and Plays a Novel Role in Alternative mRNA Splicing. Cancers , 11 (9) , Article 1233. 10.3390/cancers11091233. Green open access
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Madsen, RR; Knox, RG; Pearce, W; Lopez, S; Mahler-Araujo, B; McGranahan, N; Vanhaesebroeck, B; (2019) Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner. Proceedings of the National Academy of Sciences of The United States of America 10.1073/pnas.1821093116. (In press). Green open access
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Maggio, V; Canovas, V; Felix, AJ; Gomez, V; de Torres, I; Eugenia Semidey, M; Morote, J; ... Paciucci, R; + view all (2019) A novel DNA-binding motif in prostate tumor overexpressed-1 (PTOV1) required for the expression of ALDH1A1 and CCNG2 in cancer cells. Cancer Letters , 452 pp. 158-167. 10.1016/j.canlet.2019.03.019. Green open access
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Mahmud-Al-Rafat, A; Majumder, A; Rahman, KMT; Hasan, AMM; Islam, KMD; Taylor-Robinson, AW; Billah, MM; (2019) Decoding the enigma of antiviral crisis: Does one target molecule regulate all? Cytokine , 115 pp. 13-23. 10.1016/j.cyto.2018.12.008. Green open access
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Mak, G; Soria, J-C; Blagden, SP; Plummer, R; Fleming, RA; Nebot, N; Zhang, J; ... Arkenau, H-T; + view all (2019) A phase Ib dose-finding, pharmacokinetic study of the focal adhesion kinase inhibitor GSK2256098 and trametinib in patients with advanced solid tumours. British Journal of Cancer (120) pp. 975-981. 10.1038/s41416-019-0452-3. Green open access
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Martinez, VG; Pankova, V; Krasny, L; Singh, T; Makris, S; White, IJ; Benjamin, AC; ... Acton, SE; + view all (2019) Fibroblastic Reticular Cells Control Conduit Matrix Deposition during Lymph Node Expansion. Cell Reports , 29 (9) 2810-2822.e5. 10.1016/j.celrep.2019.10.103. Green open access
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Martínez-Mármol, R; Mohannak, N; Qian, L; Wang, T; Gormal, RS; Ruitenberg, MJ; Vanhaesebroeck, B; ... Meunier, FA; + view all (2019) p110δ PI 3-kinase inhibition perturbs APP and TNFα trafficking, reduces plaque burden, dampens neuroinflammation and prevents cognitive decline in an Alzheimer's disease mouse model. The Journal of Neuroscience , 39 (40) pp. 7976-7991. 10.1523/JNEUROSCI.0674-19.2019. Green open access
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McGranahan, N; Swanton, C; (2019) Neoantigen quality, not quantity. Science Translational Medicine , 11 (506) , Article eaax7918. 10.1126/scitranslmed.aax7918. Green open access
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McLean, BA; Patel, VB; Zhabyeyev, P; Chen, X; Basu, R; Wang, F; Shah, S; ... Oudit, GY; + view all (2019) PI3Kα Pathway Inhibition With Doxorubicin Treatment Results in Distinct Biventricular Atrophy and Remodeling With Right Ventricular Dysfunction. Journal of the American Heart Association , 8 (9) , Article e010961. 10.1161/JAHA.118.010961. Green open access
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Meric-Bernstam, F; Hurwitz, H; Raghav, KPS; McWilliams, RR; Fakih, M; VanderWalde, A; Swanton, C; ... Hainsworth, J; + view all (2019) Pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer (MyPathway): an updated report from a multicentre, open-label, phase 2a, multiple basket study. Lancet Oncology , 20 (4) pp. 518-530. 10.1016/S1470-2045(18)30904-5. Green open access
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Messaoudene, M; Mourikis, TP; Michels, J; Fu, Y; Bonvalet, M; Lacroix-Trikki, M; Routy, B; ... Zitvogel, L; + view all (2019) T-cell bispecific antibodies in node-positive breast cancer: novel therapeutic avenue for MHC class I loss variants. Annals of Oncology , 30 (6) pp. 934-944. 10.1093/annonc/mdz112. Green open access
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Miles, A; Taylor, SA; Evans, REC; Halligan, S; Beare, S; Bridgewater, J; Goh, V; ... Yu, D; + view all (2019) Patient preferences for whole-body MRI or conventional staging pathways in lung and colorectal cancer: a discrete choice experiment. European Radiology , 29 (7) pp. 3889-3900. 10.1007/s00330-019-06153-4. Green open access
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Moore, DA; Kushnir, M; Mak, G; Winter, H; Curiel, T; Voskoboynik, M; Moschetta, M; ... Arkenau, HT; + view all (2019) Prospective analysis of 895 patients on a UK Genomics Review Board. ESMO Open , 4 (2) , Article e000469. 10.1136/esmoopen-2018-000469. Green open access
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Moore, DA; Sereno, M; Das, M; Baena Acevedo, JD; Sinnadurai, S; Smith, C; McSweeney, A; ... Le Quesne, J; + view all (2019) In situ growth in early lung adenocarcinoma may represent precursor growth or invasive clone outgrowth-a clinically relevant distinction. Modern Pathology 10.1038/s41379-019-0257-1. (In press). Green open access
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Mourikis, TP; Benedetti, L; Foxall, E; Temelkovski, D; Nulsen, J; Perner, J; Cereda, M; ... Ciccarelli, FD; + view all (2019) Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma. Nature Communications , 10 (1) , Article 3101. 10.1038/s41467-019-10898-3. Green open access
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Naumann, RW; Hollebecque, A; Meyer, T; Devlin, M-J; Oaknin, A; Kerger, J; López-Picazo, JM; ... Moore, KN; + view all (2019) Safety and Efficacy of Nivolumab Monotherapy in Recurrent or Metastatic Cervical, Vaginal, or Vulvar Carcinoma: Results From the Phase I/II CheckMate 358 Trial. Journal of Clinical Oncology , 37 (31) pp. 2825-2834. 10.1200/JCO.19.00739. Green open access
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Ogunlade, O; Ho, J; Kalber, T; Hynds, R; Zhang, E; Janes, SM; Birchall, M; ... Beard, P; + view all (2019) Monitoring neovascularization and integration of decellularized human scaffolds using photoacoustic imaging. Photoacoustics , 13 pp. 76-84. 10.1016/j.pacs.2019.01.001. (In press). Green open access
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Parry, MA; Srivastava, S; Ali, A; Cannistraci, A; Antonello, J; Barros-Silva, JD; Ubertini, V; ... Baena, E; + view all (2019) Genomic Evaluation of Multiparametric Magnetic Resonance Imaging-visible and -nonvisible Lesions in Clinically Localised Prostate Cancer. European Urology Oncology , 2 (1) pp. 1-11. 10.1016/j.euo.2018.08.005. Green open access
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Paz, K; Flynn, R; Du, J; Tannheimer, S; Johnson, AJ; Dong, S; Stark, A-K; ... Blazar, BR; + view all (2019) Targeting PI3Kδ function for amelioration of murine chronic graft‐versus‐host disease. American Journal of Transplantation , 19 (6) pp. 1820-1830. 10.1111/ajt.15305. Green open access
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Pinato, DJ; Mauri, FA; Spina, P; Cain, O; Siddique, A; Goldin, R; Victor, S; ... Sharma, R; + view all (2019) Clinical implications of heterogeneity in PD-L1 immunohistochemical detection in hepatocellular carcinoma: the Blueprint-HCC study. British Journal of Cancer , 120 (12) pp. 1033-1036. 10.1038/s41416-019-0466-x. Green open access
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Plesner, T; Arkenau, HT; Gay, F; Minnema, MC; Boccadoro, M; Moreau, P; Cavenagh, J; ... Richardson, PG; + view all (2019) Enduring efficacy and tolerability of daratumumab in combination with lenalidomide and dexamethasone in patients with relapsed or relapsed/refractory multiple myeloma (GEN503): final results of an open-label, phase 1/2 study. British Journal of Haematology , 186 (3) e35-e39. 10.1111/bjh.15879. Green open access
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Powles, T; Kockx, M; Rodriguez-Vida, A; Duran, I; Crabb, SJ; Van Der Heijden, MS; Szabados, B; ... Castellano, D; + view all (2019) Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial. Nature Medicine , 25 (11) pp. 1706-1714. 10.1038/s41591-019-0628-7. Green open access
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Qayyum, MS; Hayat, H; Matharu, RK; Tabish, TA; Edirisinghe, M; (2019) Boron nitride nanoscrolls: Structure, synthesis, and applications. Applied Physics Reviews , 6 (2) , Article 021310. 10.1063/1.5092547. Green open access
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Qin, S; Finn, RS; Kudo, M; Meyer, T; Vogel, A; Ducreux, M; Macarulla, TM; ... Zhu, AX; + view all (2019) RATIONALE 301 study: tislelizumab versus sorafenib as first-line treatment for unresectable hepatocellular carcinoma. Future Oncology , 15 (16) pp. 1811-1822. 10.2217/fon-2019-0097. Green open access
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Rahman, B; Lanceley, A; Kristeleit, R; Ledermann, J; Lockley, M; McCormack, M; Mould, T; (2019) Mainstreamed genetic testing for women with ovarian cancer: first-year experience. Journal of Medical Genetics , 56 (3) pp. 195-198. 10.1136/jmedgenet-2017-105140. Green open access
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Ramage, JK; Punia, P; Faluyi, O; Frilling, A; Meyer, T; Saharan, R; Valle, JW; (2019) Observational Study to Assess Quality of Life in Patients with Pancreatic Neuroendocrine Tumors Receiving Treatment with Everolimus: The OBLIQUE Study (UK Phase IV Trial). Neuroendocrinology , 108 (4) pp. 317-327. 10.1159/000497330. Green open access
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Richardson, S; Brian, D; Grandage, V; Hough, R; Kottaridis, P; Mansour, M; Payne, EMC; (2019) Intensive Chemotherapy Is Associated With Poor Overall Survival in Autoimmune Disease-associated Myeloid Malignancies. HemaSphere , 3 (1) , Article e164. 10.1097/HS9.0000000000000164. Green open access
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Rizzo, FM; Vesely, C; Childs, A; Marafioti, T; Khan, MS; Mandair, D; Cives, M; ... Meyer, T; + view all (2019) Circulating tumour cells and their association with bone metastases in patients with neuroendocrine tumours. British Journal of Cancer , 120 (3) pp. 294-300. 10.1038/s41416-018-0367-4. Green open access
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Rooshenas, L; Scott, LJ; Blazeby, JM; Rogers, CA; Tilling, KM; Husbands, S; Conefrey, C; ... Wheatley, T; + view all (2019) The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation. Journal of Clinical Epidemiology , 106 pp. 108-120. 10.1016/j.jclinepi.2018.10.004. Green open access
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Rosenthal, R; Cadieux, EL; Salgado, R; Bakir, MA; Moore, DA; Hiley, CT; Lund, T; ... TRACERx consortium; + view all (2019) Neoantigen-directed immune escape in lung cancer evolution. Nature 10.1038/s41586-019-1032-7. (In press). Green open access
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Schiavone, F; Bathia, R; Letchmanan, K; Masters, L; Amos, C; Bara, A; Brown, L; ... Sydes, MR; + view all (2019) This is a platform alteration: a trial management perspective on the operational aspects of adaptive and platform and umbrella protocols. Trials , 20 , Article 264. 10.1186/s13063-019-3216-8. Green open access
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Shah, MA; Kojima, T; Hochhauser, D; Enzinger, P; Raimbourg, J; Hollebecque, A; Lordick, F; ... Kato, K; + view all (2019) Efficacy and Safety of Pembrolizumab for Heavily Pretreated Patients With Advanced, Metastatic Adenocarcinoma or Squamous Cell Carcinoma of the Esophagus. The Phase 2 KEYNOTE-180 Study. JAMA Oncology , 5 (4) pp. 546-550. 10.1001/jamaoncol.2018.5441.

Sharif, H; Singh, I; Kouser, L; Mösges, R; Bonny, M-A; Karamani, A; Parkin, RV; ... Shamji, MH; + view all (2019) Immunologic Mechanisms of Short-course of Lolium Perenne Peptide Immunotherapy: A Randomized Double-Blind Placebo-Controlled Trial. Journal of Allergy and Clinical Immunology , 144 (3) pp. 738-749. 10.1016/j.jaci.2019.02.023. Green open access
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Shevtsov, M; Stangl, S; Nikolaev, B; Yakovleva, L; Marchenko, Y; Tagaeva, R; Sievert, W; ... Multhoff, G; + view all (2019) Granzyme B Functionalized Nanoparticles Targeting Membrane Hsp70‐Positive Tumors for Multimodal Cancer Theranostics. Small , 15 (13) , Article 1900205. 10.1002/smll.201900205. Green open access
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Singh, AN; Oehler, J; Torrecilla, I; Kilgas, S; Li, S; Vaz, B; Guérillon, C; ... Ramadan, K; + view all (2019) The p97-Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8. The EMBO Journal , 38 (21) , Article e102361. 10.15252/embj.2019102361. Green open access
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Smeland, S; Ingleby, F; Many other authors, TPUTP; Whelan, J; Sydes, MR; (2019) Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 cohort. European Journal of Cancer , 109 pp. 36-50. 10.1016/j.ejca.2018.11.027. Green open access
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Steele, CD; Tarabichi, M; Oukrif, D; Webster, AP; Ye, H; Fittall, M; Lombard, P; ... Pillay, N; + view all (2019) Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways. Cancer Cell , 35 (3) 441-456.e8. 10.1016/j.ccell.2019.02.002. Green open access
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Stefano, P; Ivana, M; Arianna, G; Letizia, Z; Angelo, G; Rosella, C; Roberta, B; ... Andrea, G; + view all (2019) Identification of microRNAs and relative target genes in Moringa oleifera leaf and callus. Scientific Reports , 9 , Article 15145. 10.1038/s41598-019-51100-4. Green open access
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Stein, A; Dalton, L; Rapa, E; Bluebond-Langner, M; Hanington, L; Stein, KF; Ziebland, S; ... Yousafzai, A; + view all (2019) Communication with children and adolescents about the diagnosis of their own life-threatening condition. The Lancet , 393 (10176) pp. 1150-1163. 10.1016/S0140-6736(18)33201-X. Green open access
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Taylor, SA; Mallett, S; Beare, S; Bhatnagar, G; Blunt, D; Boavida, P; Bridgewater, J; ... Streamline investigators; + view all (2019) Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed colorectal cancer: the prospective Streamline C trial. The Lancet Gastroenterology & Hepatology , 4 (7) pp. 529-537. 10.1016/S2468-1253(19)30056-1. Green open access
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Teixeira, VH; Pipinikas, CP; Pennycuick, A; Lee-Six, H; Chandrasekharan, D; Beane, J; Morris, TJ; ... Janes, SM; + view all (2019) Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions. Nature Medicine , 25 pp. 517-525. 10.1038/s41591-018-0323-0. Green open access
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Tombal, B; Saad, F; Penson, D; Hussain, M; Sternberg, CN; Morlock, R; Ramaswamy, K; ... Attard, G; + view all (2019) Patient-reported outcomes following enzalutamide or placebo in men with non-metastatic, castration-resistant prostate cancer (PROSPER): a multicentre, randomised, double-blind, phase 3 trial. Lancet Oncology , 20 (4) pp. 556-569. 10.1016/S1470-2045(18)30898-2. Green open access
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Trebeschi, S; Drago, SG; Birkbak, NJ; Kurilova, I; Calin, AM; Pizzi, AD; Lalezari, F; ... Aerts, HJWL; + view all (2019) Predicting response to cancer immunotherapy using noninvasive radiomic biomarkers. Annals of Oncology , 30 (6) pp. 998-1004. 10.1093/annonc/mdz108. Green open access
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Uddin, I; Joshi, K; Oakes, T; Heather, JM; Swanton, C; TRACERx consortium, .; Chain, B; (2019) An Economical, Quantitative, and Robust Protocol for High-Throughput T Cell Receptor Sequencing from Tumor or Blood. Cancer Immunosurveillance: Methods and Protocols pp. 15-42. 10.1007/978-1-4939-8885-3_2. Green open access
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Uddin, I; Woolston, A; Peacock, T; Joshi, K; Ismail, M; Ronel, T; Husovsky, C; (2019) Quantitative analysis of the T cell receptor repertoire. Methods in Enzymology , 629 pp. 465-492. 10.1016/bs.mie.2019.05.054.

Vaarwerk, Bas; Schoot, Reineke A; Maurice-Stam, Heleen; Slater, Olga; Hartley, Benjamin; Saeed, Peerooz; Gajdosova, Eva; ... Merks, Johannes HM; + view all (2019) Psychosocial well-being of long-term survivors of pediatric head-neck rhabdomyosarcoma. Pediatric Blood & Cancer , 66 (2) , Article e27498. 10.1002/pbc.27498. Green open access
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van Noesel, MM; Orbach, D; Brennan, B; Kelsey, A; Zanetti, I; de Salvo, GL; Gaze, MN; ... Ferrari, A; + view all (2019) Outcome and prognostic factors in pediatric malignant peripheral nerve sheath tumors: An analysis of the European Pediatric Soft Tissue Sarcoma Group (EpSSG) NRSTS-2005 prospective study. Pediatric Blood and Cancer , 66 (10) , Article e27833. 10.1002/pbc.27833. Green open access
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Vanhaesebroeck, B; Bilanges, B; Madsen, RR; Dale, KL; Lau, E; Vladimirou, E; (2019) Perspective: Potential Impact and Therapeutic Implications of Oncogenic PI3K Activation on Chromosomal Instability. Biomolecules , 9 (8) , Article 331. 10.3390/biom9080331. Green open access
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Winter, H; Kaisaki, PJ; Harvey, J; Giacopuzzi, E; Ferla, MP; Pentony, MM; Knight, SJL; ... McCullagh, JSO; + view all (2019) Identification of Circulating Genomic and Metabolic Biomarkers in Intrahepatic Cholangiocarcinoma. Cancers , 11 (12) , Article 1895. 10.3390/cancers11121895. Green open access
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Wolf, Y; Bartok, O; Patkar, S; Bar Eli, G; Cohen, S; Litchfield, K; Levy, R; ... Samuels, Y; + view all (2019) UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma. Cell , 179 (1) 219-235.e21. 10.1016/j.cell.2019.08.032. Green open access
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Woodcock, HV; Eley, JD; Guillotin, D; Plate, M; Nanthakumar, CB; Martufi, M; Peace, S; ... Chambers, RC; + view all (2019) The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis. Nature Communications , 10 , Article 6. 10.1038/s41467-018-07858-8. Green open access
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Wu, A; Attard, G; (2019) Plasma DNA Analysis in Prostate Cancer: Opportunities for Improving Clinical Management. Clinical Chemistry , 65 (1) 10.1373/clinchem.2018.287250. Green open access
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Zhabyeyev, P; Chen, X; Vanhaesebroeck, B; Oudit, GY; (2019) PI3Kα in cardioprotection: Cytoskeleton, late Na+ current, and mechanism of arrhythmias. Channels , 13 (1) pp. 520-532. 10.1080/19336950.2019.1697127. Green open access
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Zhabyeyev, P; McLean, B; Chen, X; Vanhaesebroeck, B; Oudit, GY; (2019) Inhibition of PI3Kinase-α is pro-arrhythmic and associated with enhanced late Na⁺ current, contractility, and Ca²⁺ release in murine hearts. Journal of Molecular and Cellular Cardiology , 132 pp. 98-109. 10.1016/j.yjmcc.2019.05.008. Green open access
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Proceedings paper

Raza, SEA; AbdulJabbar, K; Jamal-Hanjani, M; Veeriah, S; Le Quesne, J; Swanton, C; Yuan, Y; (2019) Deconvolving Convolutional Neural Network for Cell Detection. In: 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019). (pp. pp. 891-894). IEEE: Venice, Italy,. Green open access
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Working / discussion paper

Martinez, V; Pankova, V; Krasney, L; Singh, T; White, I; Benjamin, A; dertsching, S; ... Acton, S; + view all (2019) Conduit integrity is compromised during acute lymph node expansion. BioRxiv: Cold Spring Harbor, NY, USA. Green open access
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Qin, Xiao; Sufi, Jahangir; Vlckova, Petra; Kyriakidou, Pelagia; Acton, Sophie; Li, Vivian; Nitz, Mark; (2019) Single-Cell Signalling Analysis of Heterocellular Organoids. BioRxiv: Cold Spring Harbor, NY, USA. Green open access
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Conference item

Bell, L; Potts, H; Williamson, E; (2019) P-17 Improving engagement in a health app: considerations in designing a Micro-Randomised Trial. Presented at: The 5th International Clinical Trials Methodology Conference (ICTMC 2019). Green open access
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Strasser, S; Abou-Alfa, G; Mollon, P; Meyer, T; Cheng, A; El-Khoueiry, A; Kelley, R; ... Freemantle, N; + view all (2019) Quality-adjusted life-years accrued with cabozantinib in patients with advanced hepatocellular carcinoma in the CELESTIAL trial. Presented at: Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide, Australia. Green open access
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Thesis

Carter, Thomas James; (2019) Magnetic Hyperthermia for the Treatment of Glioblastoma. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Ismail, Mazlina; (2019) Computational analysis of T cell receptor repertoires in health and disease. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Livanos, Maria; (2019) Production of DARPins in the Yeast Pichia pastoris. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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This list was generated on Mon Apr 22 02:43:24 2024 BST.