Browse by UCL people
Group by: Type | Date
Number of items: 49.
2021
Li, D;
Liu, M;
Li, Z;
Zheng, G;
Chen, A;
Zhao, L;
Yang, P;
... Ruan, XZ; + view all
(2021)
Sterol-resistant SCAP Overexpression in Vascular Smooth Muscle Cells Accelerates Atherosclerosis by Increasing Local Vascular Inflammation through Activation of the NLRP3 Inflammasome in Mice.
Aging and Disease
, 12
(3)
pp. 747-763.
10.14336/AD.2020.1120.
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Lu, J;
Chen, PP;
Zhang, JX;
Li, XQ;
Wang, GH;
Yuan, BY;
Huang, SJ;
... Ma, KL; + view all
(2021)
GPR43 deficiency protects against podocyte insulin resistance in diabetic nephropathy through the restoration of AMPKα activity.
Theranostics
, 11
(10)
pp. 4728-4742.
10.7150/thno.56598.
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Luo, X;
Zheng, E;
Wei, L;
Zeng, H;
Qin, H;
Zhang, X;
Liao, M;
... Chen, Y; + view all
(2021)
The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis.
Cell Death & Disease
, 12
(4)
, Article 328. 10.1038/s41419-021-03596-w.
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Zhao, L;
Li, Y;
Ding, Q;
Li, Y;
Chen, Y;
Ruan, XZ;
(2021)
CD36 Senses Dietary Lipids and Regulates Lipids Homeostasis in the Intestine.
Frontiers in Physiology
, 12
, Article 669279. 10.3389/fphys.2021.669279.
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Zhou, C;
He, Q;
Gan, H;
Zeng, T;
Liu, Q;
Moorhead, JF;
Varghese, Z;
... Ruan, XZ; + view all
(2021)
Hyperphosphatemia in chronic kidney disease exacerbates atherosclerosis via a mannosidases-mediated complex-type conversion of SCAP N-glycans.
Kidney International
, 99
(6)
pp. 1342-1353.
10.1016/j.kint.2021.01.016.
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2020
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Hu, ZB;
Lu, J;
Chen, PP;
Lu, CC;
Zhang, JX;
Li, XQ;
Yuan, BY;
... Ma, KL; + view all
(2020)
Dysbiosis of intestinal microbiota mediates tubulointerstitial injury in diabetic nephropathy via the disruption of cholesterol homeostasis.
Theranostics
, 10
(6)
pp. 2803-2816.
10.7150/thno.40571.
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Li, Z;
Li, D;
Rao, Y;
Wei, L;
Liu, M;
Zheng, G;
Yao, Y;
... Ruan, XZ; + view all
(2020)
SCAP knockout in SM22α-Cre mice induces defective angiogenesis in the placental labyrinth.
Biomedicine & Pharmacotherapy
, 133
, Article 111011. 10.1016/j.biopha.2020.111011.
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Lu, CC;
Hu, ZB;
Wang, R;
Hong, ZH;
Lu, J;
Chen, PP;
Zhang, JX;
... Ma, KL; + view all
(2020)
Gut microbiota dysbiosis-induced activation of the intrarenal renin–angiotensin system is involved in kidney injuries in rat diabetic nephropathy.
Acta Pharmacologica Sinica
, 41
pp. 1111-1118.
10.1038/s41401-019-0326-5.
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Luo, X;
Li, Y;
Yang, P;
Chen, Y;
Wei, L;
Yu, T;
Xia, J;
... Chen, Y; + view all
(2020)
Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function.
EBioMedicine
, 56
, Article 102797. 10.1016/j.ebiom.2020.102797.
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Sun, H;
Sun, Z;
Varghese, Z;
Guo, Y;
Moorhead, JF;
Unwin, RJ;
Ruan, XZ;
(2020)
Nonesterified free fatty acids enhance the inflammatory response in renal tubules by inducing extracellular ATP release.
American Journal of Physiology. Renal Physiology
, 319
(2)
F292-F303.
10.1152/ajprenal.00098.2020.
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Yang, P;
Zeng, H;
Tan, W;
Luo, X;
Zheng, E;
Zhao, L;
Wei, L;
... Chen, Y; + view all
(2020)
Loss of CD36 impairs hepatic insulin signaling by enhancing the interaction of PTP1B with IR.
FASEB Journal
, 34
(4)
pp. 5658-5672.
10.1096/fj.201902777RR.
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2019
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Chen, X;
Wu, Y;
Diao, Z;
Han, X;
Li, D;
Ruan, X;
Liu, W;
(2019)
C1q/tumor necrosis factor‐related protein‐3 improves renal fibrosis via inhibiting notch signaling pathways.
Journal of Cellular Physiology
, 234
(12)
pp. 22352-22364.
10.1002/jcp.28801.
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Gao, F;
Lv, Y-W;
Long, J;
Chen, J-M;
He, J-M;
Ruan, X-Z;
Zhu, H-B;
(2019)
Butyrate Improves the Metabolic Disorder and Gut Microbiome Dysbiosis in Mice Induced by a High-Fat Diet.
Frontiers in Pharmacology
, 10
, Article 1040. 10.3389/fphar.2019.01040.
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Li, D;
Chen, A;
Lan, T;
Zou, Y;
Zhao, L;
Yang, P;
Qu, H;
... Ruan, XZ; + view all
(2019)
SCAP knockdown in vascular smooth muscle cells alleviates atherosclerosis plaque formation via up-regulating autophagy in ApoE(-/-) mice.
FASEB Journal
, 33
(3)
pp. 3437-3450.
10.1096/fj.201800975RRR.
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Li, Y;
Yang, P;
Zhao, L;
Chen, Y;
Zhang, X;
Zeng, S;
Wei, L;
... Ruan, XZ; + view all
(2019)
CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway.
Journal of Lipid Research
10.1194/jlr.M090969.
(In press).
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Liu, Z;
Qian, M;
Tang, X;
Hu, W;
Sun, S;
Li, G;
Zhang, S;
... Liu, B; + view all
(2019)
SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesis.
Nature Metabolism
, 1
(11)
pp. 1141-1156.
10.1038/s42255-019-0136-6.
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Wang, G-H;
Ma, K-L;
Zhang, Y;
Hu, Z-B;
Liu, L;
Lu, J;
Chen, P-P;
... Liu, B-C; + view all
(2019)
Platelet microparticles contribute to aortic vascular endothelial injury in diabetes via the mTORC1 pathway.
Acta Pharmacologica Sinica
, 40
(4)
pp. 468-476.
10.1038/s41401-018-0186-4.
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Wang, GH;
Ma, KL;
Zhang, Y;
Hu, ZB;
Liu, L;
Lu, J;
Chen, PP;
... Liu, BC; + view all
(2019)
Caspase 3/ROCK1 pathway mediates high glucose-induced platelet microparticles shedding.
Biochemical and Biophysical Research Communications
, 509
(2)
pp. 596-602.
10.1016/j.bbrc.2018.12.166.
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Zhang, X;
Yang, P;
Luo, X;
Su, C;
Chen, Y;
Zhao, L;
Wei, L;
... Chen, Y; + view all
(2019)
High olive oil diets enhance cervical tumour growth in mice: transcriptome analysis for potential candidate genes and pathways.
Lipids in Health and Disease
, 18
, Article 76. 10.1186/s12944-019-1023-6.
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Zhou, X;
Zhao, L;
Yang, P;
Chen, Y;
Ruan, XZ;
(2019)
The Efficacy of Flupentixol-Melitracen in the Adjuvant Therapy of Ulcerative Colitis in the Chinese Population: A Meta-Analysis.
Gastroenterology Research and Practice
, 2019
, Article 3480732. 10.1155/2019/3480732.
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2018
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Gu, W;
Hong, X;
Le Bras, A;
Nowak, WN;
Bhaloo, SI;
Deng, J;
Xie, Y;
... Xu, Q; + view all
(2018)
Smooth muscle cells differentiated from mesenchymal stem cells are regulated by microRNAs and suitable for vascular tissue grafts.
Journal of Biological Chemistry
, 293
(21)
pp. 8089-8102.
10.1074/jbc.RA118.001739.
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Liu, J;
Yang, P;
Zuo, G;
He, S;
Tan, W;
Zhang, X;
Su, C;
... Chen, Y; + view all
(2018)
Long-chain fatty acid activates hepatocytes through CD36 mediated oxidative stress.
Lipids in Health and Disease
, 17
, Article 153. 10.1186/s12944-018-0790-9.
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Liu, T;
Chen, X-M;
Sun, J-Y;
Jiang, X-S;
Wu, Y;
Yang, S;
Huang, H-Z;
... Du, X-G; + view all
(2018)
Palmitic Acid-Induced Podocyte Apoptosis via the Reactive Oxygen Species-Dependent Mitochondrial Pathway.
Kidney & Blood Pressure Research
, 43
(1)
pp. 206-219.
10.1159/000487673.
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Ma, KL;
Wu, Y;
Zhang, Y;
Wang, GH;
Hu, ZB;
Ruan, XZ;
(2018)
Activation of the CXCL16/CXCR6 pathway promotes lipid deposition in fatty livers of apolipoprotein E knockout mice and HepG2 cells.
American Journal of Translational Research
, 10
(6)
pp. 1802-1816.
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Ren, L;
Sun, Y;
Lu, H;
Ye, D;
Han, L;
Wang, N;
Daugherty, A;
... Lu, X; + view all
(2018)
(Pro)renin Receptor Inhibition Reprograms Hepatic Lipid Metabolism and Protects Mice From Diet-Induced Obesity and Hepatosteatosis.
Circulation Research
, 122
(5)
pp. 730-741.
10.1161/CIRCRESAHA.117.312422.
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Sun, J;
Chen, X;
Liu, T;
Jiang, X;
Wu, Y;
Yang, S;
Hua, W;
... Du, X; + view all
(2018)
Berberine Protects Against Palmitate-Induced Apoptosis in Tubular Epithelial Cells by Promoting Fatty Acid Oxidation.
Medical Science Monitor
, 24
pp. 1484-1492.
10.12659/MSM.908927.
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Yang, P;
Su, C;
Luo, X;
Zeng, H;
Zhao, L;
Wei, L;
Zhang, X;
... Ruan, XZ; + view all
(2018)
Dietary oleic acid-induced CD36 promotes cervical cancer cell growth and metastasis via up-regulation Src/ERK pathway.
Cancer Letters
, 438
pp. 76-85.
10.1016/j.canlet.2018.09.006.
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Zhang, Y;
Ma, KL;
Gong, YX;
Wang, GH;
Hu, ZB;
Liu, L;
Lu, J;
... Liu, BC; + view all
(2018)
Platelet Microparticles Mediate Glomerular Endothelial Injury in Early Diabetic Nephropathy.
Journal of the American Society of Nephrology
, 29
(11)
pp. 2671-2695.
10.1681/ASN.2018040368.
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Zhao, L;
Varghese, Z;
Moorhead, JF;
Chen, Y;
Ruan, XZ;
(2018)
CD36 and lipid metabolism in the evolution of atherosclerosis.
British Medical Bulletin
, 126
(1)
pp. 101-112.
10.1093/bmb/ldy006.
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Zhao, L;
Zhang, C;
Luo, X;
Wang, P;
Zhou, W;
Zhong, S;
Xie, Y;
... Ruan, XZ; + view all
(2018)
CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis.
Journal of Hepatology
, 69
(3)
pp. 705-717.
10.1016/j.jhep.2018.04.006.
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Zhou, X;
Gao, H;
Guo, Y;
Chen, Y;
Ruan, XZ;
(2018)
Knocking down Stard3 decreases adipogenesis with decreased mitochondrial ROS in 3T3-L1 cells.
Biochemical and Biophysical Research Communications
, 504
(2)
pp. 387-392.
10.1016/j.bbrc.2018.06.030.
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2017
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Gao, H;
Li, D;
Yang, P;
Zhao, L;
Wei, L;
Chen, Y;
Ruan, XZ;
(2017)
Suppression of CD36 attenuates adipogenesis with a reduction of P2X7 expression in 3T3-L1 cells.
Biochemical and Biophysical Research Communications
10.1016/j.bbrc.2017.07.077.
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He, K;
Zhu, X;
Liu, Y;
Miao, C;
Wang, T;
Li, P;
Zhao, L;
... Gong, J; + view all
(2017)
Inhibition of NLRP3 inflammasome by thioredoxin-interacting protein in mouse Kupffer cells as a regulatory mechanism for non-alcoholic fatty liver disease development.
Oncotarget
, 8
(23)
pp. 37657-37672.
10.18632/oncotarget.17489.
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Huang, J;
Zhao, L;
Yang, P;
Chen, Z;
Ruan, XZ;
Huang, A;
Tang, N;
(2017)
Fatty acid translocase promoted hepatitis B virus replication by upregulating the levels of hepatic cytosolic calcium.
Experimental Cell Research
, 358
(2)
pp. 360-368.
10.1016/j.yexcr.2017.07.012.
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Jiang, X-S;
Chen, X-M;
Wan, J-M;
Gui, H-B;
Ruan, X-Z;
Du, X-G;
(2017)
Autophagy Protects against Palmitic Acid-Induced Apoptosis in Podocytes in vitro.
Scientific Reports
, 7
, Article 42764. 10.1038/srep42764.
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Kokkinopoulos, I;
Wong, MM;
Potter, CMF;
Xie, Y;
Yu, B;
Warren, DT;
Nowak, WN;
... Xu, Q; + view all
(2017)
Adventitial SCA-1(+) Progenitor Cell Gene Sequencing Reveals the Mechanisms of Cell Migration in Response to Hyperlipidemia.
Stem Cell Reports
, 9
(2)
pp. 681-696.
10.1016/j.stemcr.2017.06.011.
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Li, F;
Ruan, X;
Min, L;
(2017)
Targeting both sides of the GDF15-GFRAL-RET receptor complex: A new approach to achieve body weight homeostasis.
Genes & Diseases
, 4
(4)
pp. 183-184.
10.1016/j.gendis.2017.11.004.
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Wang, S;
Cai, R;
Yuan, Y;
Varghese, Z;
Moorhead, J;
Ruan, XZ;
(2017)
Association between reductions in low-density lipoprotein cholesterol with statin therapy and the risk of new-onset diabetes: a meta-analysis.
Scientific Reports
, 7
, Article 39982. 10.1038/srep39982.
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Wang, SH;
Cai, R;
Yuan, Y;
Varghese, Z;
Moorhead, JF;
Ruan, X;
(2017)
Association between reductions in low-density lipoprotein cholesterol with statin therapy and the risk of new-onset diabetes: a meta-analysis.
Scientific Reports
, 7
, Article 39982. 10.1038/srep39982.
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Yang, X;
Okamura, DM;
Lu, X;
Chen, Y;
Moorhead, J;
Varghese, Z;
Ruan, XZ;
(2017)
CD36 in chronic kidney disease: novel insights and therapeutic opportunities.
Nature Reviews Nephrology
, 13
pp. 769-781.
10.1038/nrneph.2017.126.
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Zhong, S;
Zhao, L;
Wang, Y;
Zhang, C;
Liu, J;
Wang, P;
Zhou, W;
... Ruan, X; + view all
(2017)
CD36 deficiency aggravates macrophage infiltration and hepatic inflammation by up-regulating MCP-1 expression of hepatocytes through HDAC2-dependant pathway.
Antioxidants & Redox Signaling
10.1089/ars.2016.6808.
(In press).
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2016
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Han, L;
Fang, X;
He, Y;
Ruan, XZ;
(2016)
ISN Forefronts Symposium 2015: IgA Nephropathy, the Gut Microbiota, and Gut−Kidney Crosstalk.
Kidney International Reports
, 1
(3)
pp. 189-196.
10.1016/j.ekir.2016.08.002.
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Huang, J;
Zhao, L;
Yang, P;
Chen, Z;
Tang, N;
Ruan, XZ;
Chen, Y;
(2016)
Genome-Wide Transcriptome Analysis of CD36 Overexpression in HepG2.2.15 Cells to Explore Its Regulatory Role in Metabolism and the Hepatitis B Virus Life Cycle.
PLoS One
, 11
(10)
, Article e0164787. 10.1371/journal.pone.0164787.
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Ruan, X;
Guan, Y;
Liu, Z-H;
Eckardt, K-U;
Unwin, R;
(2016)
Summary of ISN Forefronts Symposium
2015: ‘Immunomodulation of Cardio-Renal
Function’.
Kidney International Reports
, 1
(3)
pp. 156-165.
10.1016/j.ekir.2016.06.007.
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Sun, J;
Zhang, X;
Ruan, XZ;
(2016)
Immunity, atherogenesis and vascular function.
Experimental Physiology
, 101
(11)
pp. 1325-1326.
10.1113/EP085569.
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Wu, W;
Zhao, L;
Yang, P;
Zhou, W;
Li, B;
Moorhead, JF;
Varghese, Z;
... Chen, Y; + view all
(2016)
Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice.
PLoS One
, 11
(7)
, Article e0159512. 10.1371/journal.pone.0159512.
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2015
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Hua, W;
Huang, H-Z;
Tan, L-T;
Wan, J-M;
Gui, H-B;
Zhao, L;
Ruan, X-Z;
... Du, X-G; + view all
(2015)
CD36 Mediated Fatty Acid-Induced Podocyte Apoptosis via Oxidative Stress.
PLOS One
, 10
(5)
, Article e0127507. 10.1371/journal.pone.0127507.
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Yang, P;
Zhao, Y;
Zhao, L;
Yuan, J;
Chen, Y;
Varghese, Z;
Moorhead, JF;
... Ruan, XZ; + view all
(2015)
Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo.
Scientific Reports
, 5
, Article 14959. 10.1038/srep14959.
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2006
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Ruan, XZ;
Moorhead, JF;
Tao, JL;
Ma, KL;
Wheeler, DC;
Powis, SH;
Varghese, Z;
(2006)
Mechanisms of dysregulation of low-density lipoprotein receptor expression in vascular smooth muscle cells by inflammatory cytokines.
ARTERIOSCL THROM VAS
, 26
(5)
1150 - 1155.
10.1161/01.ATV.0000217957.93135.c2.
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