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Article

Ahmed, Aamir; Williams, Norman R; (2023) Clinical Trials and Therapeutic Approaches for Healthcare Challenges in Pakistan. Journal of Personalized Medicine , 13 (11) p. 1559. 10.3390/jpm13111559. Green open access
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Aung, Eri Yin-Soe; Khan, Maha; Williams, Norman; Raja, Usman; Hamady, Mohamad; (2022) Endovascular Stenting in Superior Vena Cava Syndrome: A Systematic Review and Meta-analysis. CardioVascular and Interventional Radiology 10.1007/s00270-022-03178-z. (In press). Green open access
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Banerjee, SM; Acedo, P; El Sheikh, S; Harati, R; Meecham, A; Williams, NR; Gerard, G; ... Hamoudi, R; + view all (2023) Combination of verteporfin-photodynamic therapy with 5-aza-2’-deoxycytidine enhances the anti-tumour immune response in triple negative breast cancer. Frontiers in Immunology , 14 , Article 1188087. 10.3389/fimmu.2023.1188087. Green open access
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Banerjee, SM; El-Sheikh, S; Malhotra, A; Mosse, CA; Parker, S; Williams, NR; MacRobert, AJ; ... Keshtgar, MR; + view all (2020) Photodynamic Therapy in Primary Breast Cancer. Journal of Clinical Medicine , 9 (2) , Article 483. 10.3390/jcm9020483. Green open access
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Best, LM; Leung, J; Freeman, SC; Sutton, AJ; Cooper, NJ; Milne, EJ; Cowlin, M; ... Gurusamy, KS; + view all (2020) Induction immunosuppression in adults undergoing liver transplantation: a network meta-analysis. Cochrane Database of Systematic Reviews , 1 , Article CD013203. 10.1002/14651858.CD013203.pub2. Green open access
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Brew-Graves, C; Farewell, V; Monson, K; Milosevic, M; Williams, NR; Morris, E; Macbeth, F; ... Fallowfield, L; + view all (2020) Pulmonary metastasectomy in colorectal cancer: health utility scores by EQ‐5D‐3L in a randomized controlled trial show no benefit from lung metastasectomy. Colorectal Disease , 23 (1) pp. 200-205. 10.1111/codi.15386. Green open access
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Cardoso, MJ; Vrieling, C; Cardoso, JS; Oliveira, HP; Williams, NR; Dixon, JM; PICTURE Project Clinical Trial Team; (2018) The value of 3D images in the aesthetic evaluation of breast cancer conservative treatment. Results from a prospective multicentric clinical trial. The Breast , 41 pp. 19-24. 10.1016/j.breast.2018.06.008. Green open access
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Catto, James WF; Khetrapal, Pramit; Ricciardi, Federico; Ambler, Gareth; Williams, Norman R; Al-Hammouri, Tarek; Khan, Muhammad Shamim; ... iROC Study Team; + view all (2022) Effect of Robot-Assisted Radical Cystectomy With Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients With Bladder Cancer: A Randomized Clinical Trial. Jounal of the American Medical Association 10.1001/jama.2022.7393. (In press).

Catto, JWF; Khetrapal, P; Ambler, G; Sarpong, R; Khan, MS; Tan, M; Feber, A; ... Kelly, JD; + view all (2018) Robot-assisted radical cystectomy with intracorporeal urinary diversion versus open radical cystectomy (iROC): protocol for a randomised controlled trial with internal feasibility study. BMJ Open , 8 (8) , Article e020500. 10.1136/bmjopen-2017-020500. Green open access
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Catto, JWF; Khetrapal, P; Ambler, G; Sarpong, R; Potyka, I; Khan, S; Tan, M; ... Kelly, JD; + view all (2018) Multidomain Quantitative Recovery Following Radical Cystectomy for Patients Within the Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion Versus Open Radical Cystectomy Randomised Controlled Trial: The First 30 Patients. European Urology , 74 (4) pp. 531-534. 10.1016/j.eururo.2018.05.008. Green open access
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Cook, Hannah; Zargaran, David; Glynou, Sevasti; Zargaran, Alexander; Akhavani, Mo; Williams, Norman; Hamilton, Stephen; (2024) Establishing Equipoise: Does the use of Acellular Dermal Matrices in pre-pectoral implant-based breast reconstruction improve outcomes? Journal of Plastic, Reconstructive and Aesthetic Surgery , 99 pp. 23-29. 10.1016/j.bjps.2024.09.041. Green open access
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Coombs, NJ; Coombs, JM; Vaidya, UJ; Singer, J; Bulsara, M; Tobias, JS; Wenz, F; ... Vaidya, JS; + view all (2016) Environmental and social benefits of the targeted intraoperative radiotherapy for breast cancer: data from UK TARGIT-A trial centres and two UK NHS hospitals offering TARGIT IORT. BMJ Open , 6 (5) , Article e010703. 10.1136/bmjopen-2015-010703. Green open access
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Corica, T; Nowak, A; Saunders, C; Bulsara, M; Taylor, M; Williams, N; Keshtgar, M; ... Vaidya, JS; + view all (2018) Cosmetic outcome as rated by patients, doctors, nurses and BCCT.core software assessed over 5 years in a subset of patients in the TARGIT-A Trial. Radiation Oncology , 13 , Article 68. 10.1186/s13014-018-0998-x. Green open access
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Dinneen, E; Almeida-Magana, R; Al-Hammouri, T; Pan, S; Leurent, B; Haider, A; Freeman, A; ... Shaw, G; + view all (2025) Effect of NeuroSAFE-guided RARP versus standard RARP on erectile function and urinary continence in patients with localised prostate cancer (NeuroSAFE PROOF): a multicentre, patient-blinded, randomised, controlled phase 3 trial. The Lancet Oncology , 26 (4) pp. 447-458. 10.1016/S1470-2045(25)00091-9. Green open access
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Dinneen, Eoin; Grierson, Jack; Almeida-Magana, Ricardo; Clow, Rosie; Haider, Aiman; Allen, Clare; Heffernan-Ho, Daniel; ... Shaw, Greg; + view all (2022) NeuroSAFE PROOF: study protocol for a single-blinded, IDEAL stage 3, multi-centre, randomised controlled trial of NeuroSAFE robotic-assisted radical prostatectomy versus standard robotic-assisted radical prostatectomy in men with localized prostate cancer. Trials , 23 , Article 584. 10.1186/s13063-022-06421-7. Green open access
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Dinneen, E; Haider, A; Allen, C; Freeman, A; Briggs, T; Nathan, S; Brew-Graves, C; ... Shaw, G; + view all (2019) NeuroSAFE robot-assisted laparoscopic prostatectomy versus standard robot-assisted laparoscopic prostatectomy for men with localised prostate cancer (NeuroSAFE PROOF): protocol for a randomised controlled feasibility study. BMJ Open , 9 (6) , Article e028132. 10.1136/bmjopen-2018-028132. Green open access
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Dinneen, E; Haider, A; Grierson, J; Freeman, A; Oxley, J; Briggs, T; Nathan, S; ... Shaw, G; + view all (2020) NeuroSAFE frozen section during robot-assisted radical prostatectomy (RARP): Peri-operative and Histopathological Outcomes from the NeuroSAFE PROOF Feasibility Randomised Controlled Trial. BJU International , 127 (6) pp. 676-686. 10.1111/bju.15256. Green open access
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Dixon, Simon; Hill, Harry; Flight, Laura; Khetrapal, Pramit; Ambler, Gareth; Williams, Norman R; Brew-Graves, Chris; ... iROC Study Team; + view all (2023) Cost-Effectiveness of Robot-Assisted Radical Cystectomy vs Open Radical Cystectomy for Patients With Bladder Cancer. JAMA Netw Open , 6 (6) , Article e2317255. 10.1001/jamanetworkopen.2023.17255. Green open access
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Eiben, B; Vavourakis, V; Hipwell, JH; Kabus, S; Buelow, T; Lorenz, C; Mertzanidou, T; ... Hawkes, DJ; + view all (2016) Symmetric Biomechanically Guided Prone-to-Supine Breast Image Registration. Annals of Biomedical Engineering , 44 (1) pp. 154-173. 10.1007/s10439-015-1496-z. Green open access
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Evans, Christopher; Bercades, Georgia; Ambler, Gareth; Wilson, Matthew; Brew-Graves, Chris; Baldini, Cinzia; Begum-Ali, Nazma; ... Moonesinghe, Suneetha Ramani; + view all (2025) Little Journey: a phase III randomised controlled trial of a psychological preparation and education smartphone application for management of paediatric perioperative anxiety compared with standard care in children undergoing ambulatory surgery - study protocol. BMJ Open , 15 (2) , Article e090696. 10.1136/bmjopen-2024-090696. Green open access
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Fabes, J; Ambler, G; Shah, B; Williams, NR; Martin, D; Davidson, BR; Spiro, M; (2021) Protocol for a prospective double-blind, randomised, placebo-controlled feasibility trial of octreotide infusion during liver transplantation. BMJ Open , 11 (12) , Article e055864. 10.1136/bmjopen-2021-055864. Green open access
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Frape, DL; Williams, NR; Carpenter, KLH; Freeman, MA; Palmer, CR; Fletcher, RJ; (2000) Insulin response and changes in composition of non-esterified fatty acids in blood plasma of middle-aged men following isoenergetic fatty and carbohydrate breakfasts. BRIT J NUTR , 84 (5) 737 - 745. 10.1017/S0007114500002105. Green open access
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Frape, DL; Williams, NR; Rajput-Williams, J; Maitland, BW; Scriven, AJ; Palmer, CR; Fletcher, RJ; (1998) Effect of breakfast fat content on glucose tolerance and risk factors of atherosclerosis and thrombosis. BRIT J NUTR , 80 (4) 323 - 331. 10.1017/S000711459800138X. Green open access
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Frape, DL; Williams, NR; Scriven, AJ; Palmer, CR; OSullivan, K; Fletcher, RJ; (1997) Diurnal trends in responses of blood plasma concentrations of glucose, insulin, and C-peptide following high- and low-fat meals and their relation to fat metabolism in healthy middle-aged volunteers. BRIT J NUTR , 77 (4) 523 - 535. 10.1079/BJN19970054. Green open access
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Frape, DL; Williams, NR; Scriven, AJ; Palmer, CR; OSullivan, K; Fletcher, RJ; (1997) Effects of high- and low-fat meals on the diurnal response of plasma lipid metabolite concentrations in healthy middle-aged volunteers. BRIT J NUTR , 77 (3) 375 - 390. 10.1079/BJN19970039. Green open access
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Fung, V; Kohlhardt, S; Vergani, P; Zardin, GJ; Williams, NR; (2017) Intraoperative prediction of the two axillary lymph node macrometastases threshold in patients with breast cancer using a one‑step nucleic acid cytokeratin‑19 amplification assay. Molecular and Clinical Oncology , 7 (5) pp. 755-762. 10.3892/mco.2017.1404. Green open access
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Ghosh, D; Michalopoulos, NV; Davidson, T; Wickham, F; Williams, NR; Keshtgar, MR; (2017) Sentinel node detection in early breast cancer with intraoperative portable gamma camera: UK experience. Breast , 32 pp. 53-59. 10.1016/j.breast.2016.12.013. Green open access
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Hamid, S; Donaldson, IA; Hu, Y; Rodell, R; Villarini, B; Bonmati, E; Tranter, P; ... Ahmed, HU; + view all (2019) The SmartTarget Biopsy Trial: A Prospective, Within-person Randomised, Blinded Trial Comparing the Accuracy of Visual-registration and Magnetic Resonance Imaging/Ultrasound Image-fusion Targeted Biopsies for Prostate Cancer Risk Stratification. European Urology , 75 (5) pp. 733-740. 10.1016/j.eururo.2018.08.007. Green open access
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Ingram, Jenny; Beasant, Lucy; Benson, John; Brunt, Adrian Murray; Maxwell, Anthony; Harvey, James Richard; Greenwood, Rosemary; ... Winters, Zoe; + view all (2022) The challenge of equipoise: qualitative interviews exploring the views of health professionals and women with multiple ipsilateral breast cancer on recruitment to a surgical randomised controlled feasibility trial. Pilot and Feasibility Studies , 8 , Article 46. 10.1186/s40814-022-01007-1. Green open access
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Inua, B; Fung, V; Al-Shurbasi, N; Howells, S; Hatsiopoulou, O; Somarajan, P; Zardin, GJ; ... Kohlhardt, S; + view all (2021) Sentinel lymph node biopsy with one-step nucleic acid assay relegates the need for preoperative ultrasound-guided biopsy staging of the axilla in patients with early stage breast cancer. Molecular and Clinical Oncology , 14 (3) , Article 51. 10.3892/mco.2021.2213. Green open access
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Kanapathy, Muholan; Faderani, Ryan; Bray, Juliette; Dehbi, Hakim-Moulay; Panca, Monica; Vindrola-Padros, Cecilia; Prasad, Anjana; ... Nikkhah, Dariush; + view all (2023) WAFER trial: a study protocol for a feasibility randomised controlled trial comparing wide-awake local anaesthesia no tourniquet (WALANT) to general and regional anaesthesia with tourniquet for flexor tendon repair. BMJ Open , 13 (8) , Article e075440. 10.1136/bmjopen-2023-075440. Green open access
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Kasivisvanathan, V; Rannikko, AS; Borghi, M; Panebianco, V; Mynderse, LA; Vaarala, MH; Briganti, A; ... PRECISION Study Group Collaborators; + view all (2018) MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis. The New England Journal of Medicine 10.1056/NEJMoa1801993. (In press). Green open access
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Keshtgar, M; Williams, NR; (2016) Intraoperative radiation therapy deserves to be made more readily available to patients. Chinese Journal of Cancer Research , 28 (4) pp. 461-462. 10.21147/j.issn.1000-9604.2016.04.10. Green open access
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Khetrapal, Pramit; Bains, Parasdeep S; Jubber, Ibrahim; Ambler, Gareth; Williams, Norman R; Brew-Graves, Chris; Sridhar, Ashwin; ... iROC Study Team; + view all (2024) Digital Tracking of Patients Undergoing Radical Cystectomy for Bladder Cancer: Daily Step Counts Before and After Surgery Within the iROC Randomised Controlled Trial. European Urology Oncology , 7 (3) pp. 485-493. 10.1016/j.euo.2023.09.021. Green open access
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Khetrapal, Pramit; Stafford, Ronnie; Ó Scanaill, Pádraig; Kocadag, Huriye; Timinis, Constantinos; Chang, Angela HL; Hadjivasiliou, Adamos; ... Kelly, John; + view all (2022) Measuring Patient Compliance With Remote Monitoring Following Discharge From Hospital After Major Surgery (DREAMPath): Protocol for a Prospective Observational Study. JMIR Research Protocols , 11 (4) , Article e30638. 10.2196/30638. Green open access
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Lacher, RM; Vasconcelos, F; Williams, N; Rindermann, G; Hipwell, J; Hawkes, D; Stoyanov, D; (2019) Nonrigid reconstruction of 3D breast surfaces with a low-cost RGBD camera for surgical planning and aesthetic evaluation. Medical Image Analysis , 53 pp. 11-25. 10.1016/j.media.2019.01.003. Green open access
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Light, Alexander; Kanthabalan, Abi; Otieno, Marjorie; Pavlou, Menelaos; Omar, Rumana; Adeleke, Sola; Giganti, Francesco; ... Shah, Taimur T; + view all (2023) The Role of Multiparametric MRI and MRI-targeted Biopsy in the Diagnosis of Radiorecurrent Prostate Cancer: An Analysis from the FORECAST Trial. European Urology 10.1016/j.eururo.2023.09.001. (In press). Green open access
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Light, Alexander; Peters, Max; Reddy, Deepika; Kanthabalan, Abi; Otieno, Marjorie; Pavlou, Menelaos; Omar, Rumana; ... Shah, Taimur T; + view all (2023) External validation of a risk model predicting failure of salvage focal ablation for prostate cancer. BJU International 10.1111/bju.16102. Green open access
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Lynch-Kelly, K; Singer, M; Williams, NR; (2017) The Landscape of Randomised Controlled Trials of Therapies in Breast Cancer in Low and Middle Income Countries. International Journal of Breast Cancer , 2017 , Article 4259704. 10.1155/2017/4259704. Green open access
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Macbeth, Fergus R; Williams, Norman R; Treasure, Tom; (2022) A Comment on the American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Colon Cancer. Diseases of the Colon & Rectum , 65 (6) , Article e662. 10.1097/DCR.0000000000002464. Green open access
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Macbeth, F; Williams, NR; Treasure, T; (2021) Pulmonary metastasectomy in colorectal cancer: a randomized controlled trial. ANZ Journal of Surgery , 91 (3) p. 473. 10.1111/ans.16658. Green open access
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Martin, DS; Brew-Graves, C; McCartan, N; Jell, G; Potyka, I; Stevens, J; Williams, NR; ... Grocott, MPW; + view all (2019) Protocol for a feasibility randomised controlled trial of targeted oxygen therapy in mechanically ventilated critically ill patients. BMJ Open , 9 (1) , Article e021674. 10.1136/bmjopen-2018-021674. Green open access
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Martin, DS; McNeil, M; Brew-Graves, C; Filipe, H; O’Driscoll, R; Stevens, JL; Burnish, R; ... Grocott, MPW; + view all (2021) A feasibility randomised controlled trial of targeted oxygen therapy in mechanically ventilated critically ill patients. Journal of the Intensive Care Society 10.1177/17511437211010031. Green open access
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Milosevic, M; Treasure, T; (2020) Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC): Updated analysis of 93 randomised patients - control survival is much better than previously assumed. Colorectal Disease 10.1111/codi.15113. (In press). Green open access
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Mokhles, S; Macbeth, F; Farewell, V; Fiorentino, F; Williams, NR; Younes, RN; Takkenberg, JJM; (2016) Meta-analysis of colorectal cancer follow-up after potentially curative resection. [Review]. British Journal of Surgery , 103 (10) pp. 1259-1268. 10.1002/bjs.10233. Green open access
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Naderi, Naghmeh; Mosahebi, Afshin; Williams, Norman R; (2023) Microorganisms and Breast Cancer: An In-Depth Analysis of Clinical Studies. Pathogens , 13 (1) , Article 6. 10.3390/pathogens13010006. Green open access
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Nathan, A; Hanna, N; Rashid, A; Patel, S; Phuah, Y; Flora, K; Fricker, M; ... Nathan, S; + view all (2021) New recommendations to reduce unnecessary blood tests after robot-assisted radical prostatectomy. BJU International , 128 (6) pp. 681-684. 10.1111/bju.15511. Green open access
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Neves, Joana B; Warren, Hannah; Santiapillai, Joseph; Rode, Nicola; Cullen, David; Pavlou, Menelaos; Walkden, Miles; ... Tran, Maxine GB; + view all (2023) Nephron Sparing Treatment (NEST) for Small Renal Masses: A Feasibility Cohort-embedded Randomised Controlled Trial Comparing Percutaneous Cryoablation and Robot-assisted Partial Nephrectomy. European Urology 10.1016/j.eururo.2023.07.012. Green open access
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Neves, J; Cullen, D; Lee, G; Walkden, M; Bandula, S; Patki, P; Barod, R; ... Tran, M; + view all (2019) Protocol for a feasibility study of a cohort embedded randomised controlled trial comparing NEphron Sparing Treatment (NEST) for small renal masses. BMJ Open , 9 (6) , Article e030965. 10.1136/bmjopen-2019-030965. Green open access
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Ney, Alexander; Nené, Nuno R; Sedlak, Eva; Acedo, Pilar; Blyuss, Oleg; Whitwell, Harry J; Costello, Eithne; ... Pereira, Stephen P; + view all (2024) Identification of a serum proteomic biomarker panel using diagnosis specific ensemble learning and symptoms for early pancreatic cancer detection. PLoS Computatonial Biology , 20 (8) , Article e1012408. 10.1371/journal.pcbi.1012408. (In press). Green open access
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Ng, Jane; Henriquez, Nico; Kitchen, Neil; Williams, Norman; Novelli, Marco; Oukrif, Dahmane; Macrobert, Alexander; (2024) Suppression of tumour growth from transplanted astrocytoma cells transfected with luciferase in mice by bioluminescence mediated, systemic, photodynamic therapy. Photodiagnosis and Photodynamic Therapy , 45 , Article 103923. 10.1016/j.pdpdt.2023.103923. Green open access
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Ng, Jane; Henriquez, Nico; MacRobert, Alexander; Kitchen, Neil; Williams, Norman; Bown, Stephen; (2022) Bioluminescence-Activated Photodynamic Therapy for Luciferase Transfected, Grade 4 Astrocytoma cells in vitro. Photodiagnosis and Photodynamic Therapy , 38 , Article 102856. 10.1016/j.pdpdt.2022.102856. Green open access
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Orczyk, C; Barratt, D; Brew-Graves, C; Peng Hu, Y; Freeman, A; McCartan, N; Potyka, I; ... Ahmed, HU; + view all (2021) Prostate Radiofrequency Focal Ablation (ProRAFT) Trial: A Prospective Development Study Evaluating a Bipolar Radiofrequency Device to Treat Prostate Cancer. Journal of Urology , 205 (4) pp. 1090-1099. 10.1097/JU.0000000000001567. Green open access
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Plaz Torres, MC; Best, LM; Freeman, SC; Roberts, D; Cooper, NJ; Sutton, AJ; Roccarina, D; ... Gurusamy, KS; + view all (2021) Secondary prevention of variceal bleeding in adults with previous oesophageal variceal bleeding due to decompensated liver cirrhosis: a network meta-analysis. Cochrane Database of Systematic Reviews , 3 , Article CD013122. 10.1002/14651858.CD013122.pub2. Green open access
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Reis, S; Gazinska, P; Hipwell, J; Mertzanidou, T; Naidoo, K; Williams, N; Pinder, S; (2017) Automated Classification of Breast Cancer Stroma Maturity from Histological Images. IEEE Transactions on Biomedical Engineering , 64 (10) pp. 2344-2352. 10.1109/TBME.2017.2665602. Green open access
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Ricketts, K; Ahmad, R; Beaton, L; Cousins, B; Critchley, K; Davies, M; Evans, S; ... Royle, G; + view all (2018) Recommendations for clinical translation of nanoparticle-enhanced radiotherapy. British Journal of Radiology , 91 (1092) , Article 20180325. 10.1259/bjr.20180325. Green open access
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Roberts, D; Best, LM; Freeman, SC; Sutton, AJ; Cooper, NJ; Arunan, S; Begum, T; ... Gurusamy, KS; + view all (2021) Treatment for bleeding oesophageal varices in people with decompensated liver cirrhosis: a network meta-analysis. Cochrane Database of Systematic Reviews , 4 , Article CD013155. 10.1002/14651858.CD013155.pub2. Green open access
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Roccarina, D; Best, LM; Freeman, SC; Roberts, D; Cooper, NJ; Sutton, AJ; Benmassaoud, A; ... Gurusamy, KS; + view all (2021) Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network meta-analysis. Cochrane Database of Systematic Reviews , 4 , Article CD013121. 10.1002/14651858.CD013121.pub2. Green open access
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Shah, Taimur T; Kanthabalan, Abi; Otieno, Marjorie; Pavlou, Menelaos; Omar, Rumana; Adeleke, Sola; Giganti, Francesco; ... Ahmed, Hashim U; + view all (2022) Magnetic Resonance Imaging and targeted biopsies compared to transperineal mapping biopsies prior to salvage focal therapy/ablation in localised and metastatic recurrent prostate cancer after radiotherapy. Primary Outcomes from the FORECAST Trial. European Urology , 81 (6) pp. 598-605. 10.1016/j.eururo.2022.02.022. Green open access
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Tan, WS; Ahmad, A; Feber, A; Mostafid, H; Cresswell, J; Fankhauser, CD; Waisbrod, S; ... DETECT I trial collaborators; + view all (2019) Development and validation of a haematuria cancer risk score to identify patients at risk of harbouring cancer. Journal of Internal Medicine , 285 (4) pp. 436-445. 10.1111/joim.12868. Green open access
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Tan, WS; Feber, A; Dong, L; Sarpong, R; Rezaee, S; Rodney, S; Khetrapal, P; ... Kelly, JD; + view all (2017) DETECT I & DETECT II: a study protocol for a prospective multicentre observational study to validate the UroMark assay for the detection of bladder cancer from urinary cells. BMC Cancer , 17 , Article 767. 10.1186/s12885-017-3758-7. Green open access
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Tan, WS; Feber, A; Sarpong, R; Khetrapal, P; Rodney, S; Jalil, R; Mostafid, H; ... Kelly, JD; + view all (2018) Who Should Be Investigated for Haematuria? Results of a Contemporary Prospective Observational Study of 3556 Patients. European Urology , 74 (1) pp. 10-14. 10.1016/j.eururo.2018.03.008. Green open access
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Tan, WS; Sarpong, R; Khetrapal, P; Rodney, S; Mostafid, H; Cresswell, J; Hicks, J; ... DETECT I trial collaborators; + view all (2018) Can renal and bladder ultrasound replace CT urogram in patients investigated for microscopic hematuria? The Journal of Urology , 200 (5) 10.1016/j.juro.2018.04.065. Green open access
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Tan, WS; Sarpong, R; Khetrapal, P; Rodney, S; Mostafid, H; Cresswell, J; Watson, D; ... DETECT I trial collaborators, .; + view all (2018) Does urinary cytology have a role in haematuria investigations? BJU International 10.1111/bju.14459. Green open access
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Tan, WS; Teo, CH; Chan, D; Ang, KM; Heinrich, M; Feber, A; Sarpong, R; ... DETECT II trial collaborators, .; + view all (2020) Exploring patients’ experience and perception of being diagnosed with bladder cancer: A mixed methods approach. BJU International , 125 (5) pp. 669-678. 10.1111/bju.15008. Green open access
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Tan, WS; Teo, CH; Chan, D; Heinrich, M; Feber, A; Sarpong, R; Allan, J; ... DETECT II trial collaborators; + view all (2019) Mix methods approach to explore patients' perspectives on the acceptability of a urinary biomarker test in replacement of cystoscopy in bladder cancer surveillance. BJU International , 124 (3) pp. 408-417. 10.1111/bju.14690. Green open access
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Tang, Stanley; Akers, Clare; Alnajjar, Hussain; Ayres, Ben; Baldini, Cinzia; Embleton-Thirsk, Andrew; Gurusamy, Kurinchi; ... Muneer, Asif; + view all (2024) A study protocol for a feasibility randomised controlled trial investigating videoendoscopic radical inguinal lymphadenectomy versus open radical inguinal lymphadenectomy in patients with penile cancer (VELRAD). Pilot and Feasibility Studies , 10 (1) , Article 61. 10.1186/s40814-024-01474-8. Green open access
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Tran, M; Neves, J; Stamati, K; Redondo, P; Cope, A; Brew-Graves, C; Williams, N; ... Emberton, M; + view all (2019) Acceptability and feasibility study of patient-specific ‘tumouroids’ as personalised treatment screening tools: protocol for prospective tissue and data collection of participants with confirmed or suspected renal cell carcinoma. International Journal of Surgery Protocols , 14 pp. 24-29. 10.1016/j.isjp.2019.03.019. Green open access
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Treasure, T; Dunning, J; Williams, NR; Macbeth, F; (2022) Lung metastasectomy for colorectal cancer: The impression of benefit from uncontrolled studies was not supported in a randomized controlled trial. The Journal of Thoracic and Cardiovascular Surgery , 163 (2) pp. 486-490. 10.1016/j.jtcvs.2021.01.142. Green open access
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Treasure, T; Farewell, V; Macbeth, F; Batchelor, T; Milosevic, M; King, J; Zheng, Y; ... PulMiCC investigators, .; + view all (2021) The Pulmonary Metastasectomy in Colorectal Cancer cohort study: Analysis of case selection, risk factors and survival in a prospective observational study of 512 patients. Colorectal Disease , 23 (7) pp. 1793-1803. 10.1111/codi.15651. Green open access
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Treasure, T; Williams, NR; Macbeth, F; (2022) The full cohort of 512 patients and the nested controlled trial in 93 patients in the Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC) study raise doubts about the effective size at present claimed. Journal of Cardiothoracic Surgery , 17 (1) , Article 9. 10.1186/s13019-022-01757-2. Green open access
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Treasure, T; Farewell, V; Macbeth, F; Batchelor, T; Milosevic, M; King, J; Zheng, Y; ... PulMiCC investigators; + view all (2021) Pulmonary Metastasectomy in Colorectal Cancer burden of care study: analysis of local treatments for lung metastases and systemic chemotherapy in 220 patients in the PulMiCC cohort. Colorectal Disease 10.1111/codi.15833. Green open access
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Treasure, T; Farewell, V; Macbeth, F; Monson, K; Williams, NR; Brew-Graves, C; Lees, B; ... PulMiCC Trial Group, .; + view all (2019) Pulmonary Metastasectomy versus Continued Active Monitoring in Colorectal Cancer (PulMiCC): a multicentre randomised clinical trial. Trials , 20 (1) , Article 718. 10.1186/s13063-019-3837-y. Green open access
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Treasure, T; Leonard, P; Milosevic, M; Williams, NR; Macbeth, F; Farewell, V; (2020) Pulmonary Metastasectomy in Colorectal Cancer: the PulMiCC randomised controlled trial. BJS (British Journal of Surgery) , 107 (11) e489-e490. 10.1002/bjs.11948. Green open access
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Treasure, T; Williams, NR; (2021) Lung metastasectomy for colorectal cancer in the PulMiCC randomised controlled trial. The Lancet Regional Health - Europe , 3 , Article 100080. 10.1016/j.lanepe.2021.100080. Green open access
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Treasure, T; Williams, NR; (2017) Best available evidence related to clinical benefit of surgical resection in multimodality treatment of metastatic colorectal cancer indicates that a randomised controlled trial is warranted. [Letter]. European Journal of Cancer , 75 pp. 310-312. 10.1016/j.ejca.2016.11.033. Green open access
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Vaidya, Jayant S; Bulsara, Max; Wenz, Frederik; Sperk, Elena; Massarut, Samuele; Alvarado, Michael; Williams, Norman R; ... Tobias, Jeffrey S; + view all (2023) In Reply to Ward et al. International Journal of Radiation: Oncology - Biology - Physics , 115 (1) pp. 256-259. 10.1016/j.ijrobp.2022.10.009. Green open access
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Vaidya, Jayant S; Joseph, David J; Tobias, Jeffrey S; Bulsara, Max; Wenz, Frederik; Saunders, Christobel; Alvarado, Michael; ... Baum, Michael; + view all (2010) Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial. The Lancet , 376 (9735) pp. 91-102. 10.1016/S0140-6736(10)60837-9. Green open access
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Vaidya, JS; Bulsara, M; Baum, M; Tobias, JS; TARGIT-A trial authors; (2021) Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment. British Journal of Cancer 10.1038/s41416-020-01233-5. (In press). Green open access
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Vaidya, JS; Bulsara, M; Baum, M; Wenz, F; Massarut, S; Pigorsch, S; Alvarado, M; ... Tobias, JS; + view all (2021) New clinical and biological insights from the international TARGIT-A randomised trial of targeted intraoperative radiotherapy during lumpectomy for breast cancer. British Journal of Cancer 10.1038/s41416-021-01440-8. (In press). Green open access
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Vaidya, JS; Bulsara, M; Baum, M; Wenz, F; Massarut, S; Pigorsch, S; Alvarado, M; ... Tobias, JS; + view all (2020) Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial. BMJ , 370 , Article m2836. 10.1136/bmj.m2836. Green open access
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Vaidya, JS; Bulsara, M; Saunders, C; Flyger, H; Tobias, JS; Corica, T; Massarut, S; ... Joseph, D; + view all (2020) Effect of Delayed Targeted Intraoperative Radiotherapy vs Whole-Breast Radiotherapy on Local Recurrence and Survival: Long-term Results From the TARGIT-A Randomized Clinical Trial in Early Breast Cancer. JAMA Oncology 10.1001/jamaoncol.2020.0249. (In press). Green open access
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Vaidya, JS; Bulsara, M; Wenz, F; Coombs, N; Singer, J; Ebbs, S; Massarut, S; ... Baum, M; + view all (2016) Reduced Mortality With Partial Breast Irradiation for Early Breast Cancer Reply. International Journal of Radiation Oncology - Biology - Physics , 96 (3) pp. 707-708. 10.1016/j.ijrobp.2016.06.2461. Green open access
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Vaidya, JS; Bulsara, M; Wenz, F; Coombs, N; Singer, J; Ebbs, S; Massarut, S; ... Baum, M; + view all (2016) Reduced Mortality With Partial-Breast Irradiation for Early Breast Cancer: A Meta-Analysis of Randomized Trials. International Journal of Radiation: Oncology - Biology - Physics , 96 (2) pp. 259-265. 10.1016/j.ijrobp.2016.05.008. Green open access
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Vaidya, JS; Wenz, F; Bulsara, M; Tobias, JS; Joseph, D; Saunders, C; Brew-Graves, C; ... Baum, M; + view all (2016) An international randomised controlled trial to compare targeted intra-operative radiotherapy (TARGIT) with conventional post-operative radiotherapy after conservative breast surgery for women with early stage breast cancer (The TARGIT-A trial). Health Technology Assessment , 20 (73) 10.3310/hta20730. Green open access
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Vaidya, JS; Wenz, F; Bulsara, M; Tobias, JS; Joseph, DJ; Keshtgar, M; Flyger, HL; ... TARGIT trialists' group, .; + view all (2014) Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial. The Lancet , 383 (9917) pp. 603-613. 10.1016/S0140-6736(13)61950-9. Green open access
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Vavourakis, V; Eiben, B; Hipwell, JH; Williams, NR; Keshtgar, M; Hawkes, DJ; (2016) Multiscale Mechano-Biological Finite Element Modelling of Oncoplastic Breast Surgery-Numerical Study towards Surgical Planning and Cosmetic Outcome Prediction. PLOS ONE , 11 (7) 10.1371/journal.pone.0159766. Green open access
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Williams, Norman R; (2023) Analysis of Clinical Trials and Review of Recent Advances in Therapy Decisions for Locally Advanced Prostate Cancer. Journal of Personalized Medicine , 13 (6) , Article 938. 10.3390/jpm13060938. Green open access
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Williams, Norman R; Patrick, Hannah; Fiorentino, Francesca; Allen, Alexander; Sharma, Manuj; Milošević, Mišel; Macbeth, Fergus; (2022) Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC) randomised controlled trial: a systematic review of published responses. European Journal of Cardio-Thoracic Surgery , 62 (1) , Article ezac253. 10.1093/ejcts/ezac253. Green open access
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Williams, Norman R; Treasure, Tom; Macbeth, Fergus; (2022) The Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC) trial results cast doubt upon benefit of lung and liver metastasectomy at the time colorectal resection. Langenbeck's Archives of Surgery , 407 pp. 881-883. 10.1007/s00423-021-02419-y. Green open access
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Williams, Norman R; Treasure, Tom; Macbeth, Fergus; (2021) Pulmonary Metastasectomy for Colorectal Cancer: Randomized Controlled Trial. Radiology , 298 (1) , Article E55. 10.1148/radiol.2020202862. Green open access
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Williams, NR; Treasure, T; Macbeth, F; Fallowfield, L; (2021) The Prospective Observational Cohort and the Nested Randomized Controlled Trial in the Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC Study) Question the Reliance on Existing Evidence for the Magnitude of Benefit From Lung Metastasectomy. American Journal of Clinical Oncology , 44 (9) pp. 502-503. 10.1097/COC.0000000000000847. Green open access
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Williams, N; Kurylcio, A; Jankiewicz, M; Romanek, J; Polkowski, W; Michalopoulos, NV; Keshtgar, MR; (2017) Aesthetic outcome after breast conserving surgery and either intraoperative radiotherapy or whole breast external beam radiotherapy for early breast cancer: Objective assessment of patients in a randomized controlled trial in Lublin, Poland. European Journal of Gynaecological Oncology , 38 (6) pp. 867-870. 10.12892/ejgo4127.2017. Green open access
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Williams, N; Pigott, KH; Brew-Graves, C; Keshtgar, MRS; (2014) Intraoperative radiotherapy for breast cancer. Gland Surgery , 3 (2) pp. 109-119. Green open access
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Williams, NR; Macbeth, F; Treasure, T; (2020) Pulmonary metastasectomy in colorectal cancer: PulMiCC and future trials. Quantitative Imaging in Medicine and Surgery , 10 (11) pp. 2215-2217. 10.21037/qims-20-774. Green open access
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Williams, NR; Pigott, KH; Keshtgar, MR; (2011) Intraoperative radiotherapy in the treatment of breast cancer: a review of the evidence. International Journal of Breast Cancer , 2011 , Article 375170. 10.4061/2011/375170. Green open access
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Williams, NR; Williams, S; Kanapathy, M; Naderi, N; Vavourakis, V; Mosahebi, A; (2019) Radiation-induced fibrosis in breast cancer: A protocol for an observational cross-sectional pilot study for personalised risk estimation and objective assessment. International Journal of Surgery Protocols , 14 pp. 9-13. 10.1016/j.isjp.2019.02.002. Green open access
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Winters, Z; Horsnell, J; Elvers, KT; Maxwell, AJ; Jones, LJ; Shaaban, AM; Schmid, P; ... Brunt, AM; + view all (2018) Systematic review of the impact of breast-conserving surgery on cancer outcomes of multiple ipsilateral breast cancers. British Journal of Surgery , 2 (4) pp. 162-174. 10.1002/bjs5.53. Green open access
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Winters, ZE; Horsnell, J; Schmid, P; Jones, JL; Shaaban, A; Maxwell, AJ; Williams, N; ... MIAMI Trial Management Group, .; + view all (2016) Time for a randomised clinical trial evaluating breast conserving surgery compared to mastectomy in ipsilateral mutlifocal breast cancer (MFBC)? The Breast , 26 pp. 149-150. 10.1016/j.breast.2015.12.011. Green open access
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Woolf, DK; Williams, NR; Bakshi, R; Madani, SY; Eaton, DJ; Fawcitt, S; Pigott, K; ... Keshtgar, M; + view all (2014) Biological dosimetry for breast cancer radiotherapy: a comparison of external beam and intraoperative radiotherapy. Springerplus , 3 , Article 329. 10.1186/2193-1801-3-329. Green open access
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Zheng, Yan; Treasure, Tom; Williams, Norman R; (2021) A history of lung metastasectomy may be told in narratives but we need randomized controlled trials to know what treatments should be used in the future. AME Surgical Journal 10.21037/asj-21-91. (In press). Green open access
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Proceedings paper

Eiben, B; Vavourakis, V; Hipwell, JH; Kabus, S; Lorenz, C; Buelow, T; Williams, NR; ... Hawkes, DJ; + view all (2016) Surface Driven Biomechanical Breast Image Registration. In: Webster, RJ and Yaniv, ZR, (eds.) Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling. (pp. 97860W:1-97860W:10). Society of Photo-Optical Instrumentation Engineers (SPIE) Green open access
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Lacher, RM; Vasconcelos, F; Bishop, DC; Williams, NR; Keshtgar, M; Hawkes, DJ; Hipwell, JH; (2017) A comparative study of breast surface reconstruction for aesthetic outcome assessment. In: Descoteaux, M and Maier-Hein, L and Franz, A and Jannin, P and Collins, D, (eds.) Medical Image Computing and Computer-Assisted Intervention − MICCAI 2017. (pp. pp. 514-522). Springer: Cham. Green open access
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Conference item

Winters, Z; Horsnell, J; Elvers, K; Maxwell, A; Jones, LJ; Shaaban, AM; Schmid, P; ... Brunt, AM; + view all (2018) Systematic Review of impact of BCS on cancer outcomes in Multiple Ipsilateral Breast Cancers (MIBC) - rationale for MIAMI randomised trial. Presented at: Association of Breast Surgery Annual Scientific Meeting, Birmingham, UK. Green open access
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Winters, ZE; Jones, L; Schmidt, P; Brunt, M; Maxwell, A; Ingram, J; Greenwood, R; ... Williams, N; + view all (2020) Can patients with multiple breast cancers in the same breast avoid mastectomy by having multiple lumpectomies to achieve equivalent rates of local breast cancer recurrence? A randomized controlled feasibility trial called MIAMI UK (NCT03514654). Presented at: 2nd UK Interdisciplinary Breast Cancer Symposium (UKIBCS), Manchester, England. (In press). Green open access
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Poster

Neves, JB; Flight, J; Cullen, D; Grant, L; Walkden, M; Bandula, S; Patki, P; ... Tran, MGB; + view all (2019) Protocol for a Feasibility Study of a Cohort Embedded Randomised Controlled Trial comparing NEphron Sparing Treatment (NEST) for Small Renal Masses. Presented at: 18th International Kidney Cancer Symposium, Miami, FL, USA. Green open access
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Vaidya, Jayant S; Williams, Norman; Bulsara, Max; Baum, Michael; Brew-Graves, Chris; Potyka, Ingrid; Roberts, Nick; ... Tobias, Jeffrey S; + view all (2025) Substantially lower lung cancer incidence with TARGIT-IORT (targeted intraoperative radiotherapy) compared with whole breast radiotherapy in the TARGIT-A randomised trial for breast cancer: 25-year update. Presented at: British Association of Surgical Oncology ~ Association for Cancer Surgery Annual Conference 2025, London, UK. Green open access
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Thesis

Williams, NR; (1992) Zinc and human pregnancy. Doctoral thesis (Ph.D), UNSPECIFIED.

This list was generated on Sun Feb 8 06:03:01 2026 GMT.