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Surface Driven Biomechanical Breast Image Registration

Eiben, B; Vavourakis, V; Hipwell, JH; Kabus, S; Lorenz, C; Buelow, T; Williams, NR; ... Hawkes, DJ; + view all (2016) Surface Driven Biomechanical Breast Image Registration. In: Webster, RJ and Yaniv, ZR, (eds.) Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling. (pp. 97860W:1-97860W:10). Society of Photo-Optical Instrumentation Engineers (SPIE) Green open access

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Abstract

Biomechanical modelling enables large deformation simulations of breast tissues under different loading conditions to be performed. Such simulations can be utilised to transform prone Magnetic Resonance (MR) images into a different patient position, such as upright or supine. We present a novel integration of biomechanical modelling with a surface registration algorithm which optimises the unknown material parameters of a biomechanical model and performs a subsequent regularised surface alignment. This allows deformations induced by effects other than gravity, such as those due to contact of the breast and MR coil, to be reversed. Correction displacements are applied to the biomechanical model enabling transformation of the original pre-surgical images to the corresponding target position. The algorithm is evaluated for the prone-to-supine case using prone MR images and the skin outline of supine Computed Tomography (CT) scans for three patients. A mean target registration error (TRE) of 10:9 mm for internal structures is achieved. For the prone-to-upright scenario, an optical 3D surface scan of one patient is used as a registration target and the nipple distances after alignment between the transformed MRI and the surface are 10:1 mm and 6:3 mm respectively.

Type: Proceedings paper
Title: Surface Driven Biomechanical Breast Image Registration
Event: Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling, 27 February - 3 March 2016, San Diego, California, USA
Location: San Diego, CA
Dates: 28 February 2016 - 01 March 2016
Open access status: An open access version is available from UCL Discovery
DOI: 10.1117/12.2216728
Publisher version: https://doi.org/10.1117/12.2216728
Language: English
Additional information: This is the published version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: breast cancer, biomechanical modelling, surface alignment, registration, large deformation simulation, finite elements
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10050850
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