Browse by UCL people
Group by: Type | Date
Number of items: 170.
Article
Abdel-Aty, H;
O'Shea, L;
Amos, C;
Brown, LC;
Grist, E;
Attard, G;
Clarke, N;
... James, N; + view all
(2023)
The STAMPEDE2 Trial: a Site Survey of Current Patterns of Care, Access to Imaging and Treatment of Metastatic Prostate Cancer.
Clinical Oncology
, 35
(10)
e628-e635.
10.1016/j.clon.2023.07.009.
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Abdel-Rahman, ME;
Butler, J;
Sydes, MR;
Parmar, MK;
Gordon, E;
Harper, P;
Williams, C;
... Coleman, MP; + view all
(2014)
No socioeconomic inequalities in ovarian cancer survival within two randomised clinical trials.
Br J Cancer
, 111
(3)
pp. 589-597.
10.1038/bjc.2014.303.
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ACTIV-3/TICO LY-CoV555 Study Group;
(2021)
A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19.
The New England Journal of Medicine
, 384
pp. 905-914.
10.1056/NEJMoa2033130.
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Adams, RA;
Fisher, DJ;
Graham, J;
Seligmann, JF;
Seymour, M;
Kaplan, R;
Yates, E;
... FOCUS4 Trial Investigators; + view all
(2021)
Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial.
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
10.1200/JCO.21.01436.
(In press).
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Aggarwal, A;
Court, LE;
Hoskin, P;
Jacques, I;
Kroiss, M;
Laskar, S;
Lievens, Y;
... Langley, R; + view all
(2023)
ARCHERY: a prospective observational study of artificial intelligence-based radiotherapy treatment planning for cervical, head and neck and prostate cancer - study protocol.
BMJ Open
, 13
(12)
, Article e077253. 10.1136/bmjopen-2023-077253.
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Ahmed, HU;
El-Shater Bosaily, A;
Brown, LC;
Gabe, R;
Kaplan, R;
Parmar, MK;
Collaco-Moraes, Y;
... PROMIS study group; + view all
(2017)
Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study.
Lancet
, 389
(10071)
pp. 815-822.
10.1016/S0140-6736(16)32401-1.
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Ali, A;
Hoyle, AP;
Parker, CC;
Brawley, CD;
Cook, A;
Amos, C;
Calvert, J;
... STAMPEDE investigators; + view all
(2021)
Bone metastatic burden as a predictor of survival benefit from prostate radiotherapy in newly-diagnosed metastatic prostate cancer.
JAMA oncology
, 7
(4)
pp. 555-563.
10.1001/jamaoncol.2020.7857.
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Ali, A;
Plus 12 other authors, TPUWPO;
Sydes, M;
Clarke, NW;
(2020)
The Automated Bone Scan Index as a Predictor of Response to Prostate Radiotherapy in Men with Newly Diagnosed Metastatic Prostate Cancer: An Exploratory Analysis of STAMPEDE’s “M1|RT Comparison”.
European Urology Oncology
, 3
(4)
pp. 412-419.
10.1016/j.euo.2020.05.003.
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Attard, G;
Brown, LC;
Clarke, NW;
Parmar, MKB;
James, ND;
(2021)
Should Patients with High-risk Localised or Locally Advanced Prostate Cancer Receive Abiraterone Acetate in Addition to Androgen Deprivation Therapy? Update on a Planned Analysis of the STAMPEDE Trial.
European Urology
, 80
(4)
pp. 522-523.
10.1016/j.eururo.2021.06.023.
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Attard, G;
Murphy, L;
Clarke, NW;
Sachdeva, A;
Jones, C;
Hoyle, A;
Cross, W;
... McPhail, N; + view all
(2023)
Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol.
The Lancet Oncology
, 24
(5)
pp. 443-456.
10.1016/S1470-2045(23)00148-1.
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Bailey, K;
Ryan, A;
Apostolidou, S;
Fourkala, E;
Burnell, M;
Gentry-Maharaj, A;
Kalsi, J;
... Menon, U; + view all
(2015)
Socioeconomic indicators of health inequalities and female mortality: a nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).
BMC Public Health
, 15
(253)
, Article 1609. 10.1186/s12889-015-1609-5.
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Barthel, FM-S;
Parmar, MKB;
Royston, P;
(2009)
How do multi-stage, multi-arm trials compare to the traditional two-arm parallel group design - a reanalysis of 4 trials.
Trials
, 10
, Article 21. 10.1186/1745-6215-10-21.
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Bedia, Jacob S;
Jacobs, Ian J;
Ryan, Andy;
Gentry-Maharaj, Aleksandra;
Burnell, Matthew;
Singh, Naveena;
Manchanda, Ranjit;
... Skates, Steven J; + view all
(2025)
Estimating the ovarian cancer CA-125 preclinical detectable phase, in-vivo tumour doubling time, and window for detection in early stage: an exploratory analysis of UKCTOCS.
eBioMedicine
, 112
, Article 105554. 10.1016/j.ebiom.2024.105554.
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Bell, R;
Brown, J;
Parmar, M;
Toi, M;
Suter, T;
Steger, GG;
Pivot, X;
... Cameron, D; + view all
(2017)
Final efficacy and updated safety results of the randomized phase III BEATRICE trial evaluating adjuvant bevacizumab-containing therapy in triple-negative early breast cancer.
Annals of Oncology
, 28
(4)
pp. 754-760.
10.1093/annonc/mdw665.
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Bird, SM;
Strang, J;
Ashby, D;
Podmore, J;
Robertson, JR;
Welch, S;
Meade, AM;
(2017)
External data required timely response by the Trial Steering-Data Monitoring Committee for the NALoxone InVEstigation (N-ALIVE) pilot trial.
Contemporary Clinical Trials Communications
, 5
pp. 100-106.
10.1016/j.conctc.2017.01.006.
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Blenkinsop, A;
Parmar, MK;
Choodari-Oskooei, B;
(2019)
Assessing the impact of efficacy stopping rules on the error rates under the multi-arm multi-stage framework.
Clinical Trials
10.1177/1740774518823551.
(In press).
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Blyuss, O;
Burnell, M;
Ryan, A;
Gentry-Maharaj, A;
Marino, I;
Kalsi, J;
Manchanda, R;
... Menon, U; + view all
(2018)
Comparison of longitudinal CA125 algorithms as a first line screen for ovarian cancer in the general population.
Clinical Cancer Research
10.1158/1078-0432.CCR-18-0208.
(In press).
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Bouche, Gauthier;
Gilbert, Duncan;
Quartagno, Matteo;
Dehbi, Hakim-Moulay;
Merrick, Sophie;
Barjesteh van Waalwijk van Doorn-Khosrovani, Sahar;
Stephens, Richard;
... Langley, Ruth E; + view all
(2025)
Determining the optimal use of approved drugs in oncology.
The Lancet Oncology
, 26
(5)
e282-e294.
10.1016/S1470-2045(25)00037-3.
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Bratton, DJ;
Parmar, MK;
Phillips, PP;
Choodari-Oskooei, B;
(2016)
Type I error rates of multi-arm multi-stage clinical trials: strong control and impact of intermediate outcomes.
Trials
, 17
, Article 309. 10.1186/s13063-016-1382-5.
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Bratton, DJ;
Phillips, PP;
Parmar, MK;
(2013)
A multi-arm multi-stage clinical trial design for binary outcomes with application to tuberculosis.
BMC Medical Research Methodology
, 13
, Article 139. 10.1186/1471-2288-13-139.
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Brown, LC;
Ahmed, HU;
Faria, R;
El-Shater Bosaily, A;
Gabe, R;
Kaplan, RS;
Parmar, M;
... Emberton, M; + view all
(2018)
Multiparametric MRI to improve detection of prostate cancer compared with transrectal ultrasound-guided prostate biopsy alone: the PROMIS study.
Health Technology Assessment
, 22
(39)
xxxiii, 1-175.
10.3310/hta22390.
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Burdett, S;
Fisher, DJ;
Vale, CL;
Bono, AV;
Clarke, NW;
Cognetti, F;
Collette, L;
... Tierney, JF; + view all
(2022)
Adjuvant Chemotherapy for Muscle-invasive Bladder Cancer: A Systematic Review and Meta-analysis of Individual Participant Data from Randomised Controlled Trials.
European Urology
, 81
(1)
pp. 50-61.
10.1016/j.eururo.2021.09.028.
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Burdett, S;
Boeve, L;
Ingleby, F;
Fisher, D;
Rydzewska, L;
Vale, C;
van Andel, G;
... Tierney, J; + view all
(2019)
Prostate Radiotherapy for Metastatic Hormone-sensitive Prostate Cancer: A STOPCAP Systematic Review and Meta-analysis.
European Urology
10.1016/j.eururo.2019.02.003.
(In press).
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Burdett, S;
Rydzewska, L;
Tierney, J;
Fisher, D;
Parmar, MKB;
Arriagada, R;
Pignon, JP;
... PORT Meta-analysis Trialists Group, .; + view all
(2016)
Postoperative radiotherapy for non-small cell lung cancer.
Cochrane Database of Systematic Reviews
, 10
, Article CD002142. 10.1002/14651858.CD002142.pub4.
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Burnell, M;
Gentry-Maharaj, A;
Glazer, C;
Karpinskyj, C;
Ryan, A;
Apostolidou, S;
Kalsi, J;
... Menon, U; + view all
(2020)
Serial endometrial thickness and risk of non-endometrial hormone-dependent cancers in postmenopausal women in UKCTOCS.
Ultrasound in Obstetrics & Gynecology
, 56
(2)
pp. 267-275.
10.1002/uog.21894.
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Burnell, M;
Gentry-Maharaj, A;
Ryan, A;
Apostolidou, S;
Habib, M;
Kalsi, J;
Skates, S;
... Menon, U; + view all
(2011)
Impact on mortality and cancer incidence rates of using random invitation from population registers for recruitment to trials.
Trials
, 12
, Article 61. 10.1186/1745-6215-12-61.
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Burnell, M;
Gentry-Maharaj, A;
Skates, SJ;
Ryan, A;
Karpinskyj, C;
Kalsi, J;
Apostolidou, S;
... Menon, U; + view all
(2021)
UKCTOCS update: applying insights of delayed effects in cancer screening trials to the long-term follow-up mortality analysis.
Trials
, 22
, Article 173. 10.1186/s13063-021-05125-8.
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Choodari-Oskooei, B;
Bratton, DJ;
Gannon, MR;
Meade, AM;
Sydes, MR;
Parmar, MKB;
(2020)
Adding new experimental arms to randomised clinical trials: Impact on error rates.
Clinical Trials
10.1177/1740774520904346.
(In press).
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Choodari-Oskooei, B;
Parmar, MK;
Royston, P;
Bowden, J;
(2013)
Impact of lack-of-benefit stopping rules on treatment effect estimates of two-arm multi-stage (TAMS) trials with time to event outcome.
Trials
, 14
, Article 23. 10.1186/1745-6215-14-23.
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Choodari-Oskooei, B;
Royston, P;
Parmar, MKB;
(2015)
The extension of total gain (TG) statistic in survival models: Properties and applications.
BMC Medical Research Methodology
, 15
(1)
, Article 50. 10.1186/s12874-015-0042-x.
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Choudhury, T;
Mozid, A;
Hamshere, S;
Yeo, C;
Pellaton, C;
Arnous, S;
Saunders, N;
... Mathur, A; + view all
(2017)
An exploratory randomized control study of combination cytokine and adult autologous bone marrow progenitor cell administration in patients with ischaemic cardiomyopathy: the REGENERATE-IHD clinical trial.
European Journal of Heart Failure
, 19
(1)
pp. 138-147.
10.1002/ejhf.676.
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Choudry, F;
Hamshere, S;
Saunders, N;
Veerapen, J;
Bavnbek, K;
Knight, C;
Pellerin, D;
... Mathur, A; + view all
(2016)
A randomized double-blind control study of early intra-coronary autologous bone marrow cell infusion in acute myocardial infarction: the REGENERATE-AMI clinical trial†.
European Heart Journal
, 37
(3)
pp. 256-263.
10.1093/eurheartj/ehv493.
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Clamp, AR;
James, EC;
McNeish, IA;
Dean, A;
Kim, J-W;
O'Donnell, DM;
Hook, J;
... Ledermann, JA; + view all
(2019)
Weekly dose-dense chemotherapy in first-line epithelial ovarian, fallopian tube, or primary peritoneal carcinoma treatment (ICON8): primary progression free survival analysis results from a GCIG phase 3 randomised controlled trial.
The Lancet
10.1016/s0140-6736(19)32259-7.
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Clarke, Caroline S;
Hunter, Rachael M;
Gabrio, Andrea;
Brawley, Christopher D;
Ingleby, Fiona C;
Dearnaley, David P;
Matheson, David;
... James, Nicholas D; + view all
(2022)
Cost-utility analysis of adding abiraterone acetate plus prednisone/prednisolone to long-term hormone therapy in newly diagnosed advanced prostate cancer in England: Lifetime decision model based on STAMPEDE trial data.
PLoS One
, 17
(6)
, Article e0269192. 10.1371/journal.pone.0269192.
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Clarke, NW;
Ali, A;
Ingleby, FC;
Hoyle, A;
Amos, CL;
Attard, G;
Brawley, CD;
... STAMPEDE investigators; + view all
(2020)
Corrigendum to Addition of docetaxel to hormonal therapy in low- and high-burden metastatic hormone sensitive prostate cancer: long-term survival results from the STAMPEDE trial: Ann Oncol 2019; 30: 1992-2003.
[Corrigendum].
Annals of Oncology
, 31
(3)
p. 442.
10.1016/j.annonc.2020.01.002.
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Clarke, NW;
Ali, A;
Ingleby, FC;
Hoyle, A;
Amos, CL;
Attard, G;
Brawley, CD;
... James, ND; + view all
(2019)
Addition of docetaxel to hormonal therapy in low- and high-burden metastatic hormone sensitive prostate cancer: long-term survival results from the STAMPEDE trial.
Annals of Oncology
10.1093/annonc/mdz396.
(In press).
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Collinson, F;
Qian, W;
Fossati, R;
Lissoni, A;
Williams, C;
Parmar, M;
Ledermann, J;
... on behalf of the ICON1 collaborators; + view all
(2014)
Optimal treatment of early-stage ovarian cancer.
Ann Oncol
, 25
(6)
pp. 1165-1171.
10.1093/annonc/mdu116.
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Dearnaley, DP;
Jovic, G;
Syndikus, I;
Khoo, V;
Cowan, RA;
Graham, JD;
Aird, EG;
... Sydes, MR; + view all
(2014)
Escalated-dose versus control-dose conformal radiotherapy for prostate cancer: long-term results from the MRC RT01 randomised controlled trial.
The Lancet Oncology
, 15
(4)
464 - 473.
10.1016/S1470-2045(14)70040-3.
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Dilley, J;
Burnell, M;
Gentry-Maharaj, A;
Ryan, A;
Neophytou, C;
Apostolidou, S;
Karpinskyj, C;
... Menon, U; + view all
(2020)
Ovarian cancer symptoms, routes to diagnosis and survival – Population cohort study in the ‘no screen’ arm of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).
Gynecologic Oncology
10.1016/j.ygyno.2020.05.002.
(In press).
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Douin, David J;
Siegel, Lianne;
Grandits, Greg;
Phillips, Andrew;
Aggarwal, Neil R;
Baker, Jason;
Brown, Samuel M;
... ACTIV-3/Therapeutics for Inpatients with COVID-19 (TICO) Study G; + view all
(2022)
Evaluating Primary Endpoints for COVID-19 Therapeutic Trials to Assess Recovery.
American Journal of Respiratory and Critical Care Medicine
, 206
(6)
pp. 730-739.
10.1164/rccm.202112-2836OC.
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Downing, A;
Morris, EJ;
Corrigan, N;
Sebag-Montefiore, D;
Finan, PJ;
Thomas, JD;
Chapman, M;
... Selby, P; + view all
(2017)
High hospital research participation and improved colorectal cancer survival outcomes: a population-based study.
Gut
, 66
(1)
pp. 89-96.
10.1136/gutjnl-2015-311308.
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Eisen, T;
Frangou, E;
Oza, B;
Ritchie, AWS;
Smith, B;
Kaplan, R;
Davis, ID;
... Meade, A; + view all
(2020)
Adjuvant Sorafenib for Renal Cell Carcinoma at Intermediate or High Risk of Relapse: Results From the SORCE Randomized Phase III Intergroup Trial.
Journal of Clinical Oncology
, 38
(34)
pp. 4064-4075.
10.1200/jco.20.01800.
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Embleton-Thirsk, A;
Deane, E;
Townsend, S;
Farrelly, L;
Popoola, B;
Parker, J;
Rustin, G;
... Kaplan, R; + view all
(2019)
Impact of retrospective data verification to prepare the ICON6 trial for use in a marketing authorization application.
Clinical Trials
, 16
(5)
pp. 502-511.
10.1177/1740774519862528.
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Field, JK;
Vulkan, D;
Davies, MPA;
Baldwin, DR;
Brain, KE;
Devaraj, A;
Eisen, T;
... Duffy, SW; + view all
(2021)
Lung cancer mortality reduction by LDCT screening: UKLS randomised trial results and international meta-analysis.
The Lancet Regional Health - Europe
, 10
, Article 100179. 10.1016/j.lanepe.2021.100179.
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Field, JK;
Duffy, SW;
Baldwin, DR;
Brain, KE;
Devaraj, A;
Eisen, T;
Green, BA;
... Hansell, DM; + view all
(2016)
The UK Lung Cancer Screening Trial: a pilot randomised controlled trial of low-dose computed tomography screening for the early detection of lung cancer.
Health Technology Assessment
, 20
(40)
10.3310/hta20400.
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Field, JK;
Duffy, SW;
Baldwin, DR;
Whynes, DK;
Devaraj, A;
Brain, KE;
Eisen, T;
... Hansell, DM; + view all
(2016)
UK Lung Cancer RCT Pilot Screening Trial: baseline findings from the screening arm provide evidence for the potential implementation of lung cancer screening.
Thorax
, 71
(2)
pp. 161-170.
10.1136/thoraxjnl-2015-207140.
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Fourkala, EO;
Burnell, M;
Cox, C;
Ryan, A;
Salter, LC;
Gentry-Maharaj, A;
Parmar, M;
... Menon, U; + view all
(2014)
Association of skirt size and postmenopausal breast cancer risk in older women: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).
BMJ Open
, 4
(9)
, Article e005400. 10.1136/bmjopen-2014-005400.
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Gentry-Maharaj, A;
Blyuss, O;
Ryan, A;
Burnell, M;
Karpinskyj, C;
Gunu, R;
Kalsi, JK;
... Menon, U; + view all
(2020)
Multi-Marker Longitudinal Algorithms Incorporating HE4 and CA125 in Ovarian Cancer Screening of Postmenopausal Women.
Cancers
, 12
(7)
, Article 1931. 10.3390/cancers12071931.
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Gentry-Maharaj, A;
Glazer, C;
Burnell, M;
Ryan, A;
Berry, H;
Kalsi, J;
Woolas, R;
... Menon, U; + view all
(2017)
Changing trends in reproductive/lifestyle factors in UK women: descriptive study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).
BMJ Open
, 7
(3)
, Article e011822. 10.1136/bmjopen-2016-011822.
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Ghimire, Bhagabati;
Landy, Rebecca;
Maroni, Roberta;
Smith, Samuel G;
Debiram-Beecham, Irene;
Sasieni, Peter D;
Fitzgerald, Rebecca C;
... Offman, Judith; + view all
(2023)
Predictors of the experience of a Cytosponge test: analysis of patient survey data from the BEST3 trial.
BMC Gastroenterology
, 23
(1)
, Article 7. 10.1186/s12876-022-02630-1.
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Ghorani, E;
Quartagno, M;
Blackhall, F;
Gilbert, DC;
O'Brien, M;
Ottensmeier, C;
Pizzo, E;
... on behalf of the REFINE-Lung, Investigators; + view all
(2023)
REFINE-Lung implements a novel multi-arm randomised trial design to address possible immunotherapy overtreatment.
The Lancet Oncology
, 24
(5)
e219-e227.
10.1016/S1470-2045(23)00095-5.
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Gilbert, DC;
Nankivell, M;
Rush, H;
Clarke, NW;
Mangar, S;
Al-Hasso, A;
Rosen, S;
... Langley, RE; + view all
(2023)
A Repurposing Programme Evaluating Repurposing Transdermal Oestradiol Patches for the Treatment of Prostate Cancer Within the PATCH and STAMPEDE Trials: Current Results and Adapting Trial Design.
Clinical Oncology
10.1016/j.clon.2023.10.054.
(In press).
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Gilbert, DC;
Duong, T;
Kynaston, HG;
Alhasso, AA;
Cafferty, FH;
Rosen, SD;
Kanaga-Sundaram, S;
... Abel, PD; + view all
(2017)
Quality of life outcomes from the PATCH trial evaluating LHRH agonists versus transdermal oestradiol for androgen suppression in advanced prostate cancer.
BJU International
, 119
(5)
pp. 667-675.
10.1111/bju.13687.
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Gilbert, DC;
Duong, T;
Sydes, M;
Bara, A;
Clarke, N;
Abel, P;
James, N;
... STAMPEDE and PATCH Trial Management Groups, .; + view all
(2018)
Transdermal oestradiol as a method of androgen suppression for prostate cancer within the STAMPEDE trial platform.
BJU International
, 121
(5)
pp. 680-683.
10.1111/bju.14153.
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Gilson, C;
Chowdhury, S;
Parmar, MKB;
Sydes, MR;
STAMPEDE Investigators;
(2017)
Incorporating Biomarker Stratification into STAMPEDE: an Adaptive Multi-arm, Multi-stage Trial Platform.
Clinical Oncology
, 29
(12)
pp. 778-786.
10.1016/j.clon.2017.10.004.
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Gilson, C;
Ingleby, F;
Gilbert, DC;
Parry, MA;
Atako, NB;
Ali, A;
Hoyle, A;
... Chowdhury, S; + view all
(2020)
Genomic Profiles of De Novo High- and Low-Volume Metastatic Prostate Cancer: Results From a 2-Stage Feasibility and Prevalence Study in the STAMPEDE Trial.
JCO Precision Oncology
, 4
pp. 882-897.
10.1200/po.19.00388.
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Glasbey, J;
Beggs, A;
Glimelius, B;
Gray, R;
Handley, K;
Laurberg, S;
Magill, L;
... Furniss, D; + view all
(2024)
Risk of Bowel Obstruction in Patients Undergoing Neoadjuvant Chemotherapy for High-risk Colon Cancer: A Nested Case-control-matched Analysis of an International, Multicenter, Randomized Controlled Trial (FOxTROT).
Annals of Surgery
, 280
(2)
pp. 283-293.
10.1097/SLA.0000000000006145.
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González Martín, A;
Oza, A;
Embleton, AC;
Pfisterer, J;
Ledermann, J;
Pujade-Lauraine, E;
Kristensen, G;
... Perren, T; + view all
(2019)
Exploratory outcome analyses according to stage and/or residual disease in the ICON7 trial of carboplatin and paclitaxel with or without bevacizumab for newly diagnosed ovarian cancer.
Gynecologic Oncology
, 152
(1)
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Randomized controlled pilot trial of naloxone-on-release to prevent post-prison opioid overdose deaths.
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Salvage radiotherapy after radical prostatectomy: analysis of toxicity by dose-fractionation in the RADICALS-RT trial.
International Journal of Radiation: Oncology - Biology - Physics
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The DURATIONS randomised trial design: Estimation targets, analysis methods and operating characteristics.
Clinical Trials
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Combined test versus logrank/Cox test in 50 randomised trials.
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A simulation study comparing the power of nine tests of the treatment effect in randomized controlled trials with a time-to-event outcome.
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Augmenting the logrank test in the design of clinical trials in which non-proportional hazards of the treatment effect may be anticipated.
BMC Medical Research Methodology
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Royston, P;
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An approach to trial design and analysis in the era of non-proportional hazards of the treatment effect.
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Royston, P;
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Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome.
BMC MEDICAL RESEARCH METHODOLOGY
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Quality of Life in Men With Prostate Cancer Randomly Allocated to Receive Docetaxel or Abiraterone in the STAMPEDE Trial.
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Adding abiraterone to androgen deprivation therapy in men with metastatic hormone-sensitive prostate cancer: A systematic review and meta-analysis.
European Journal of Cancer
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Response to letter commenting on published paper: Adding abiraterone to androgen deprivation therapy in men with metastatic hormone-sensitive prostate cancer: A systematic review and meta-analysis.
European Journal of Cancer
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10.1016/j.ejca.2018.02.002.
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Sabin, T;
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A quantitative process for enhancing end of phase 2 decisions.
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Schiavone, F;
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This is a platform alteration: a trial management perspective on the operational aspects of adaptive and platform and umbrella protocols.
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Seligmann, JF;
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Inhibition of WEE1 Is Effective in TP53- and RAS-Mutant Metastatic Colorectal Cancer: A Randomized Trial (FOCUS4-C) Comparing Adavosertib (AZD1775) With Active Monitoring.
Journal of Clinical Oncology
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South, A;
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Effectiveness and acceptability of methods of communicating the results of clinical research to lay and professional audiences: protocol for a systematic review.
Systematic Reviews
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South, A;
Parulekar, WR;
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Chen, BE;
Parmar, MK;
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Estimating the Impact of Randomised Control Trial Results on Clinical Practice: Results from a Survey and Modelling Study of Androgen Deprivation Therapy plus Radiotherapy for Locally Advanced Prostate Cancer.
European Urology Focus
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STARSurg Collaborative;
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Anaesthesia
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10.1111/anae.16220.
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Stephens, RJ;
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Interim results in clinical trials: Do we need to keep all interim randomised clinical trial results confidential?
Lung Cancer
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Self-reported transvaginal ultrasound visualization of normal ovaries in postmenopausal women is not reliable: results of expert review of archived images in UKCTOCS.
Ultrasound Obstet Gynecol
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Audit of transvaginal sonography of normal postmenopausal ovaries by sonographers from the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).
F1000 Research
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Sydes, MR;
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Adding abiraterone or docetaxel to long-term hormone therapy for prostate cancer: directly randomised data from the STAMPEDE multi-arm, multi-stage platform protocol.
Annals Of Oncology
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Sydes, MR;
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Survival with Newly Diagnosed Metastatic Prostate Cancer in the “Docetaxel Era”: Data from 917 Patients in the Control Arm of the STAMPEDE Trial (MRC PR08, CRUK/06/019).
European Urology
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10.1016/j.eururo.2014.09.032.
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Sydes, MR;
Johnson, AL;
Meredith, SK;
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Sharing data from clinical trials: the rationale for a controlled access approach.
Trials
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Sydes, MR;
Parmar, MK;
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Amos, C;
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Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial.
Trials
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Sydes, MR;
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Clarke, NW;
Dearnaley, DP;
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Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial.
Trials
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Taylor, JA;
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Association of hysterectomy and invasive epithelial ovarian and tubal cancer: a cohort study within UKCTOCS.
BJOG: An International Journal of Obstetrics and Gynaecology
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10.1111/1471-0528.16943.
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Tierney, J;
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Timely and reliable evaluation of the effects of interventions: a framework for adaptive meta-analysis (FAME).
Trials
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Tierney, JF;
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Comparison of aggregate and individual participant data approaches to meta-analysis of randomised trials: An observational study.
PLoS Med
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Tierney, JF;
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A framework for prospective, adaptive meta-analysis (FAME) of aggregate data from randomised trials.
PLoS Medicine
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Tierney, JF;
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How individual participant data meta-analyses have influenced trial design, conduct, and analysis.
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10.1016/j.jclinepi.2015.05.024.
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Vale, CL;
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Should Tyrosine Kinase Inhibitors Be Considered for Advanced Non-Small-Cell Lung Cancer Patients With Wild Type EGFR? Two Systematic Reviews and Meta-Analyses of Randomized Trials.
Clinical Lung Cancer
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10.1016/j.cllc.2014.11.007.
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(2016)
Addition of docetaxel or bisphosphonates to standard of care in men with localised or metastatic, hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggregate data.
The Lancet Oncology
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10.1016/S1470-2045(15)00489-1.
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Vale, CL;
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Adjuvant or early salvage radiotherapy for the treatment of localised and locally advanced prostate cancer: a prospectively planned systematic review and meta-analysis of aggregate data.
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Vale, CL;
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What is the optimal systemic treatment of men with metastatic, hormone-naive prostate cancer? A STOPCAP systematic review and network meta-analysis.
Annals of Oncology
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Etzioni, R;
Kessler, LG;
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Considerations for using potential surrogate endpoints in cancer screening trials.
The Lancet Oncology
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10.1016/S1470-2045(24)00015-9.
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Wong, Charis;
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Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease.
BMJ Open
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Woods, BS;
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Addition of Docetaxel to First-line Long-term Hormone Therapy in Prostate Cancer (STAMPEDE): Modelling to Estimate Long-term Survival, Quality-adjusted Survival, and Cost-effectiveness.
European Urology Oncology
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10.1016/j.euo.2018.06.004.
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Zakeri, K;
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Predictive classifier for intensive treatment of head and neck cancer.
Cancer
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10.1002/cncr.33212.
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Zeissler, M-L;
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Is It Possible to Conduct a Multi-Arm Multi-Stage Platform Trial in Parkinson's Disease: Lessons Learned from Other Neurodegenerative Disorders and Cancer.
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Addition of docetaxel to first-line long-term hormone therapy in prostate cancer (STAMPEDE): Long-term survival, quality-adjusted survival, and cost-effectiveness analysis.
In: Figlin, Robert and Spielberg, Steven, (eds.)
Proceedings of the 2018 Genitourinary Cancers Symposium.
American Society of Clinical Oncology (ASCO): San Francisco, CA, USA.
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Working / discussion paper
Burnell, M;
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Kalsi, J;
Apostolidou, S;
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(2020)
UKCTOCS Update: Applying insights of delayed effects in cancer screening trials to the long-term follow-up mortality analysis.
MedRxiv: Cold Spring Harbor, NY, USA.
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Conference item
Cook, A;
Embleton, A;
Jayson, G;
Kaplan, R;
Kristensen, G;
Parmar, MK;
Pfisterer, J;
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(2017)
ICON7: Ovarian cancer, platinum second-line chemotherapy and overall survival.
Presented at: 42nd ESMO Congress (ESMO 2017), Madrid, Spain.
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Gentry-Maharaj, A;
Skates, S;
Sharma, A;
Burnell, M;
Ryan, A;
Grant, S;
Ford, J;
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Risk of Ovarian Cancer (Roc) Algorithm Increases Specificity of Ca125 in Ovarian Cancer Screening.
Presented at: International Gynecologic Cancer Society (IGCS), Santa Monica, CA, USA.
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Langley, RE;
Duong, T;
Clarke, NW;
Kynaston, K;
Rosen, SD;
Nankivell, M;
Dearnaley, D;
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(2018)
PATCH - Prostate adenocarcinoma: transcutaneous hormones. A randomised comparison evaluating cardiovascular morbidity and mortality of transdermal oestradiol versus luteinising hormone-releasing hormone agonists in advanced prostate cancer.
Presented at: The British Associations of Urological Surgeons (BAUS) Annual Scientific Meeting, Liverpool, UK.
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