Browse by UCL people
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Number of items: 86.
Article
Altmann, Daniel M;
Reynolds, Catherine J;
Joy, George;
Otter, Ashley D;
Gibbons, Joseph M;
Pade, Corinna;
Swadling, Leo;
... Boyton, Rosemary J; + view all
(2023)
Persistent symptoms after COVID-19 are not associated with differential SARS-CoV-2 antibody or T cell immunity.
Nature Communications
, 14
(1)
, Article 5139. 10.1038/s41467-023-40460-1.
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Amin, OE;
Colbeck, EJ;
Daffis, S;
Khan, S;
Ramakrishnan, D;
Pattabiraman, D;
Chu, R;
... Pallett, LJ; + view all
(2020)
Therapeutic potential of TLR8 agonist GS-9688 (selgantolimod) in chronic hepatitis B: re-modelling of antiviral and regulatory mediators.
Hepatology
, 74
(1)
pp. 55-71.
10.1002/hep.31695.
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Arenas-Pinto, A;
Milinkovic, A;
Peppa, D;
McKendry, A;
Maini, M;
Gilson, R;
(2015)
Systemic inflammation and residual viraemia in HIV-positive adults on protease inhibitor monotherapy: a cross-sectional study.
BMC Infect Dis
, 15
(1)
, Article 138. 10.1186/s12879-015-0889-9.
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Barreby, Emelie;
Strunz, Benedikt;
Nock, Sebastian;
Naudet, Léa;
Shen, Joanne X;
Johansson, Helene;
Sönnerborg, Isabella;
... Aouadi, Myriam; + view all
(2023)
Human resident liver myeloid cells protect against metabolic stress in obesity.
Nature Metabolism
10.1038/s42255-023-00834-7.
(In press).
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Bertoletti, Antonio;
Le Bert, Nina;
Tan, Anthony T;
Boni, Carolina;
Fisicaro, Paola;
Ferrari, Carlo;
Chang, Kyong-Mi;
... Neumann-Haefelin, Christoph; + view all
(2023)
Comment on ‘End-of-treatment HBcrAg and HBsAb levels identify durable functional cure after Peg-IFN-based therapy in patients with CHB’.
[Letter].
Journal of Hepatology
, 79
(5)
e202-e204.
10.1016/j.jhep.2023.05.032.
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Burton, AR;
Maini, MK;
(2021)
Human antiviral B cell responses: Emerging lessons from hepatitis B and COVID-19.
Immunological Reviews
10.1111/imr.12953.
(In press).
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Burton, AR;
Pallett, LJ;
McCoy, LE;
Suveizdyte, K;
Amin, OE;
Swadling, L;
Alberts, E;
... Maini, MK; + view all
(2018)
Circulating and intrahepatic antiviral B cells are defective in hepatitis B.
Journal of Clinical Investigation
, 2018
pp. 1-16.
10.1172/JCI121960.
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Chandran, Aneesh;
Rosenheim, Joshua;
Nageswaran, Gayathri;
Swadling, Leo;
Pollara, Gabriele;
Gupta, Rishi K;
Burton, Alice R;
... Noursadeghi, Mahdad; + view all
(2022)
Rapid synchronous type 1 IFN and virus-specific T cell responses characterize first wave non-severe SARS-CoV-2 infections.
Cell Reports Medicine
, Article 100557. 10.1016/j.xcrm.2022.100557.
(In press).
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Chinnakannan, SK;
Cargill, TN;
Donnison, TA;
Ansari, MA;
Sebastian, S;
Lee, LN;
Hutchings, C;
... Barnes, E; + view all
(2020)
The Design and Development of a Multi-HBV Antigen Encoded in Chimpanzee Adenoviral and Modified Vaccinia Ankara Viral Vectors; A Novel Therapeutic Vaccine Strategy against HBV.
Vaccines
, 8
(2)
, Article 184. 10.3390/vaccines8020184.
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Cornberg, M;
Lok, AS-F;
Terrault, NA;
Zoulim, F;
2019 EASL-AASLD HBV Treatment Endpoints Conference Faculty;
(2020)
Guidance for design and endpoints of clinical trials in chronic hepatitis B - Report from the 2019 EASL-AASLD HBV Treatment Endpoints Conference.
Hepatology
, 71
(3)
pp. 1070-1092.
10.1002/hep.31030.
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Cuff, AO;
Robertson, FP;
Stegmann, KA;
Pallett, LJ;
Maini, MK;
Davidson, BR;
Male, V;
(2016)
Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation.
Journal of Immunology
, 197
(11)
, Article 1601424. 10.4049/jimmunol.1601424.
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de Silva, TI;
Liu, G;
Lindsey, BB;
Dong, D;
Moore, SC;
Hsu, NS;
Shah, D;
... Dong, T; + view all
(2021)
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells.
iScience
, 24
(11)
, Article 103353. 10.1016/j.isci.2021.103353.
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Di Scala, M;
Otano, I;
Gil-Farina, I;
Vanrell, L;
Hommel, M;
Olague, C;
Vales, A;
... Gonzalez-Aseguinolaza, G; + view all
(2016)
Complementary Effects of Interleukin-15 and Alpha Interferon Induce Immunity in Hepatitis B Virus Transgenic Mice.
Journal of Virology
, 90
(19)
pp. 8563-8574.
10.1128/JVI.01030-16.
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Diniz, Mariana O;
Mitsi, Elena;
Swadling, Leo;
Rylance, Jamie;
Johnson, Marina;
Goldblatt, David;
Ferreira, Daniela;
(2022)
Airway-resident T cells from unexposed individuals cross-recognize SARS-CoV-2.
Nature Immunology
10.1038/s41590-022-01292-1.
(In press).
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Diniz, Mariana O;
Schurich, Anna;
Chinnakannan, Senthil K;
Duriez, Marion;
Stegmann, Kerstin A;
Davies, Jessica;
Kucykowicz, Stephanie;
... Maini, Mala K; + view all
(2022)
NK cells limit therapeutic vaccine-induced CD8+T cell immunity in a PD-L1-dependent manner.
Science Translational Medicine
, 14
(640)
, Article eabi4670. 10.1126/scitranslmed.abi4670.
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Diniz, MO;
Maini, MK;
Swadling, L;
(2023)
T cell control of SARS-CoV-2: When, which, and where?
Seminars in Immunology
, 70
, Article 101828. 10.1016/j.smim.2023.101828.
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Dunn, C;
Brunetto, M;
Reynolds, G;
Christophides, T;
Kennedy, PT;
Lampertico, P;
Das, A;
... Maini, MK; + view all
(2007)
Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage.
J EXP MED
, 204
(3)
667 - 680.
10.1084/jem.20061287.
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Duriez, M;
Mandouri, Y;
Lekbaby, B;
Wang, H;
Schnuriger, A;
Redelsperger, F;
Guerrera, CI;
... Soussan, P; + view all
(2017)
Alternative splicing of hepatitis B virus: A novel virus/host interaction altering liver immunity.
Journal of Hepatology
, 67
(4)
pp. 687-699.
10.1016/j.jhep.2017.05.025.
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Dusheiko, Geoffrey;
Agarwal, Kosh;
Maini, Mala K;
(2023)
New Approaches to Chronic Hepatitis B.
New England Journal of Medicine
, 388
pp. 55-69.
10.1056/NEJMra2211764.
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Easom, NJW;
Marks, M;
Jobe, D;
Gillmore, R;
Meyer, T;
Maini, MK;
Njie, R;
(2020)
ULBP1 Is Elevated in Human Hepatocellular Carcinoma and Predicts Outcome.
Frontiers in Oncology
, 10
, Article 971. 10.3389/fonc.2020.00971.
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Easom, NJW;
Stegmann, KA;
Swadling, L;
Pallett, LJ;
Burton, AR;
Odera, D;
Schmidt, N;
... Maini, MK; + view all
(2018)
IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction.
Frontiers in Immunology
, 9
, Article 1009. 10.3389/fimmu.2018.01009.
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Fergusson, JR;
Wallace, Z;
Connolly, MM;
Woon, AP;
Suckling, RJ;
Hine, DW;
Barber, C;
... Knox, A; + view all
(2020)
Immune-Mobilizing Monoclonal T Cell Receptors Mediate Specific and Rapid Elimination of Hepatitis B-Infected Cells.
Hepatology
, 72
(5)
pp. 1528-1540.
10.1002/hep.31503.
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Fidler, S;
Stöhr, W;
Pace, M;
Dorrell, L;
Lever, A;
Pett, S;
Kinloch-de Loes, S;
... RIVER trial study group; + view all
(2020)
Antiretroviral therapy alone versus antiretroviral therapy with a kick and kill approach, on measures of the HIV reservoir in participants with recent HIV infection (the RIVER trial): a phase 2, randomised trial.
Lancet
, 395
(10227)
pp. 888-898.
10.1016/S0140-6736(19)32990-3.
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Fink, DL;
Etoori, D;
Hill, R;
Idilli, O;
Kartikapallil, N;
Payne, O;
Griffith, S;
... Gill, US; + view all
(2025)
Auto-antibodies against interferons are common in people living with chronic hepatitis B virus infection and associate with PegIFN non-response.
JHEP Reports
, Article 101382. 10.1016/j.jhepr.2025.101382.
(In press).
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García-López, M;
Lens, S;
Pallett, LJ;
Testoni, B;
Rodríguez-Tajes, S;
Mariño, Z;
Bartres, C;
... Pérez-Del-Pulgar, S; + view all
(2020)
Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients.
Journal of Hepatology
10.1016/j.jhep.2020.11.043.
(In press).
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Gehring, Adam J;
Mendez, Patricia;
Richter, Kirsten;
Ertl, Hildegund;
Donaldson, Eric F;
Mishra, Poonam;
Maini, Mala;
... Miller, Veronica; + view all
(2022)
Immunological Biomarker Discovery in Cure Regimens for Chronic Hepatitis B Virus Infection.
Journal of Hepatology
, 77
(2)
pp. 525-538.
10.1016/j.jhep.2022.02.020.
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Gehring, AJ;
Koh, S;
Chia, A;
Paramasivam, K;
Chew, VSP;
Ho, ZZ;
Lee, KH;
... Bertoletti, A; + view all
(2011)
Licensing Virus-Specific T Cells to Secrete the Neutrophil Attracting Chemokine CXCL-8 during Hepatitis B Virus Infection.
PLOS ONE
, 6
(8)
, Article e23330. 10.1371/journal.pone.0023330.
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Gill, US;
Pallett, LJ;
Kennedy, PTF;
Maini, MK;
(2018)
Liver sampling: a vital window into HBV pathogenesis on the path to functional cure.
Gut
, 67
(4)
10.1136/gutjnl-2017-314873.
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Gill, US;
Pallett, LJ;
Thomas, N;
Burton, AR;
Patel, AA;
Yona, S;
Kennedy, PTF;
(2018)
Fine needle aspirates comprehensively sample intrahepatic immunity.
Gut
10.1136/gutjnl-2018-317071.
(In press).
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Gill, US;
Peppa, D;
Micco, L;
Singh, HD;
Carey, I;
Foster, GR;
Maini, MK;
(2016)
Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo.
PLoS Pathog
, 12
(8)
, Article e1005788. 10.1371/journal.ppat.1005788.
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Gilroy, D;
Pereira, B;
De Maeyer, R;
covre, L;
Nehar-Belaid, D;
Lanna, A;
Ward, S;
... Akbar, A; + view all
(2020)
Sestrins induce natural killer function in senescent-like CD8+ T cells.
Nature Immunology
, 21
pp. 684-694.
10.1038/s41590-020-0643-3.
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Gupta, RK;
Rosenheim, J;
Bell, LC;
Chandran, A;
Guerra-Assuncao, JA;
Pollara, G;
Whelan, M;
... COVIDsortium Investigators, .; + view all
(2021)
Blood transcriptional biomarkers of acute viral infection for detection of pre-symptomatic SARS-CoV-2 infection: a nested, case-control diagnostic accuracy study.
Lancet Microbe
10.1016/S2666-5247(21)00146-4.
(In press).
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Heiberg, IL;
Pallett, LJ;
Winther, TN;
Høgh, B;
Maini, MK;
Peppa, D;
(2015)
Defective natural killer cell anti-viral capacity in paediatric HBV infection.
Clin Exp Immunol
, 179
(3)
466 - 476.
10.1111/cei.12470.
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Huang, W-C;
Easom, NJ;
Tang, X-Z;
Gill, US;
Singh, H;
Robertson, F;
Chang, C;
... Maini, MK; + view all
(2017)
T Cells Infiltrating Diseased Liver Express Ligands for the NKG2D Stress Surveillance System.
Journal of Immunology
, 198
(3)
pp. 1172-1182.
10.4049/jimmunol.1601313.
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Jeffery-Smith, A;
Burton, AR;
Lens, S;
Rees-Spear, C;
Davies, J;
Patel, M;
Gopal, R;
... Maini, MK; + view all
(2022)
SARS-CoV-2-specific memory B cells can persist in the elderly who have lost detectable neutralising antibodies.
Journal of Clinical Investigation
, 132
(2)
, Article e152042.. 10.1172/JCI152042.
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Khakpoor, A;
Ni, Y;
Chen, A;
Ho, ZZ;
Oei, V;
Yang, N;
Giri, R;
... Bertoletti, A; + view all
(2018)
Spatio-temporal differences in presentation of CD8 T cell epitopes during HBV infection.
Journal of Virology
10.1128/JVI.01457-18.
(In press).
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Laing, N;
Tufton, H;
Ochola, E;
P'Kingston, OG;
Maini, MK;
Easom, N;
(2019)
Hepatitis B assessment without hepatitis B virus DNA quantification: a prospective cohort study in Uganda.
Transactions of The Royal Society of Tropical Medicine and Hygiene
, 113
(1)
pp. 11-17.
10.1093/trstmh/try117.
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Lascar, R.M.;
Lopes, A.R.;
Gilson, R.J.;
Dunn, C.;
Johnstone, R.;
Copas, A.;
Reignat, S.;
... Maini, M.K.; + view all
(2005)
Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection.
The Journal of Infectious Diseases
, 191
(7)
pp. 1169-1179.
10.1086/428502.
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Lascar, RM;
Gilson, RJ;
Lopes, AR;
Bertoletti, A;
Maini, MK;
(2003)
Reconstitution of hepatitis B virus (HBV)-specific T cell responses with treatment of human immunodeficiency virus/HBV coinfection.
J INFECT DIS
, 188
(12)
1815 - 1819.
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Lim, Seng Gee;
Baumert, Thomas F;
Boni, Carolina;
Gane, Ed;
Levrero, Massimo;
Lok, Anna S;
Maini, Mala K;
... Zoulim, Fabien; + view all
(2023)
The scientific basis of combination therapy for chronic hepatitis B functional cure.
Nature Reviews Gastroenterology & Hepatology
, 20
pp. 238-253.
10.1038/s41575-022-00724-5.
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Maini, MK;
(2023)
Tissue T cells in prophylactic and therapeutic vaccination responses.
Seminars in Arthritis and Rheumatism
, 63
, Article 152287. 10.1016/j.semarthrit.2023.152287.
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Maini, MK;
Burton, AR;
(2019)
Restoring, releasing or replacing adaptive immunity in chronic hepatitis B.
Nature Reviews Gastroenterology & Hepatology
, 16
pp. 662-675.
10.1038/s41575-019-0196-9.
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Maini, MK;
Pallett, LJ;
(2018)
Defective T-cell immunity in hepatitis B virus infection: why therapeutic vaccination needs a helping hand.
The Lancet Gastroenterology & Hepatology
, 3
(3)
pp. 192-202.
10.1016/S2468-1253(18)30007-4.
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Maini, MK;
Peppa, D;
(2020)
Shared immunotherapeutic approaches in HIV and hepatitis B virus: combine and conquer.
Current Opinion in HIV and AIDS
, 15
(3)
pp. 157-164.
10.1097/COH.0000000000000621.
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Maini, MK;
Peppa, D;
(2013)
NK cells: a double-edged sword in chronic hepatitis B virus infection.
Front Immunol
, 4
, Article 57. 10.3389/fimmu.2013.00057.
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Male, V;
Stegmann, KA;
Easom, NJ;
Maini, MK;
(2017)
Natural Killer Cells in Liver Disease.
[Review].
Seminars in Liver Disease
, 37
(3)
pp. 198-209.
10.1055/s-0037-1603946.
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Manisty, C;
Treibel, TA;
Jensen, M;
Semper, A;
Joy, G;
Gupta, RK;
Cutino-Moguel, T;
... Moon, JC; + view all
(2021)
Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection.
EBioMedicine
, 65
, Article 103259. 10.1016/j.ebiom.2021.103259.
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Mitsi, E;
Diniz, MO;
Reiné, J;
Collins, AM;
Robinson, RE;
Hyder-Wright, A;
Farrar, M;
... Ferreira, DM; + view all
(2023)
Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination.
Nature Communications
, 14
(1)
, Article 6815. 10.1038/s41467-023-42433-w.
(In press).
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Nebbia, G;
Peppa, D;
Schurich, A;
Khanna, P;
Singh, HD;
Cheng, Y;
Rosenberg, W;
... Maini, MK; + view all
(2012)
Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection.
PLOS One
, 7
(10)
, Article e47648. 10.1371/journal.pone.0047648.
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Otano, I;
Escors, D;
Schurich, A;
Singh, H;
Robertson, F;
Davidson, BR;
Fusai, G;
... Maini, MK; + view all
(2018)
Molecular Recalibration of PD-1+ Antigen-Specific T Cells from Blood and Liver.
Molecular Therapy
10.1016/j.ymthe.2018.08.013.
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Pallett, Laura J;
Maini, Mala K;
(2022)
Liver-resident memory T cells: life in lockdown.
Seminars in Immunopathology
10.1007/s00281-022-00932-w.
(In press).
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Pallett, Laura J;
Swadling, Leo;
Diniz, Mariana;
Maini, Alexander A;
Schwabenland, Marius;
Gasull, Adrià Dalmau;
Davies, Jessica;
... Maini, Mala K; + view all
(2023)
Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS.
Nature
, 614
pp. 334-342.
10.1038/s41586-022-05645-6.
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Pallett, LJ;
Burton, AR;
Amin, OE;
Rodriguez-Tajes, S;
Patel, AA;
Zakeri, N;
Jeffery-Smith, A;
... Maini, MK; + view all
(2020)
Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes.
Journal of Experimental Medicine
, 217
(9)
, Article e20200050. 10.1084/jem.20200050.
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Pallett, LJ;
Davies, J;
Colbeck, EJ;
Robertson, F;
Hansi, N;
Easom, NJW;
Burton, AR;
... Maini, MK; + view all
(2017)
IL-2(high) tissue-resident T cells in the human liver: Sentinels for hepatotropic infection.
Journal of Experimental Medicine
, 214
(6)
pp. 1567-1580.
10.1084/jem.20162115.
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Pallett, LJ;
Gill, US;
Quaglia, A;
Sinclair, LV;
Jover-Cobos, M;
Schurich, A;
Singh, KP;
... Maini, MK; + view all
(2015)
Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.
Nature Medicine
, 21
(6)
pp. 591-600.
10.1038/nm.3856.
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Peppa, D;
Micco, L;
Javaid, A;
Kennedy, PTF;
Schurich, A;
Dunn, C;
Pallant, C;
... Maini, MK; + view all
(2010)
Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection.
PLOS PATHOG
, 6
(12)
, Article e1001227. 10.1371/journal.ppat.1001227.
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Peppa, D;
Pedroza-Pacheco, I;
Pellegrino, P;
Williams, I;
Maini, MK;
Borrow, P;
(2018)
Adaptive Reconfiguration of Natural Killer Cells in HIV-1 Infection.
Frontiers in Immunology
, 9
, Article 474. 10.3389/fimmu.2018.00474.
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Perpiñán, E;
Pérez-Del-Pulgar, S;
Londoño, M-C;
Mariño, Z;
Bartres, C;
González, P;
García-López, M;
... Koutsoudakis, G; + view all
(2020)
Cirrhosis Hampers Early and Rapid Normalization of Natural Killer Cell Phenotype and Function in Hepatitis C Patients Undergoing Interferon-Free Therapy.
Frontiers Immunology
, 11
, Article 129. 10.3389/fimmu.2020.00129.
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Peters, Marion G;
Yuen, Man-Fung;
Terrault, Norah;
Fry, John;
Lampertico, Pietro;
Gane, Ed;
Hwang, Carey;
... Lenz, Oliver; + view all
(2024)
Chronic Hepatitis B Finite Treatment: similar and different concerns with new drug classes.
Clinical Infectious Diseases
, 78
(4)
pp. 983-990.
10.1093/cid/ciad506.
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Preece, R;
Pavesi, A;
Gkazi, SA;
Stegmann, KA;
Georgiadis, C;
Tan, ZM;
Joey Aw, JY;
... Qasim, W; + view all
(2020)
CRISPR mediated base conversion allows discriminatory depletion of endogenous T cell receptors for enhanced synthetic immunity.
Molecular Therapy: Methods & Clinical Development
10.1016/j.omtm.2020.09.002.
(In press).
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Reignat, S.;
Webster, G.J.M.;
Brown, D.;
Ogg, G.S.;
King, A.;
Seneviratne, S.L.;
Dusheiko, G.;
... Bertoletti, A.; + view all
(2002)
Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection.
Journal of Experimental Medicine
, 195
(9)
pp. 1089-1101.
10.1084/jem.20011723.
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Reynolds, CJ;
Gibbons, JM;
Pade, C;
Lin, K-M;
Sandoval, DM;
Pieper, F;
Butler, DK;
... Boyton, RJ; + view all
(2021)
Heterologous infection and vaccination shapes immunity against SARS-CoV-2 variants.
Science
, Article eabm0811. 10.1126/science.abm0811.
(In press).
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Reynolds, CJ;
Pade, C;
Gibbons, JM;
Butler, DK;
Otter, AD;
Menacho, K;
Fontana, M;
... Boyton, R; + view all
(2021)
Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose.
Science
, Article eabh1282. 10.1126/science.abh1282.
(In press).
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Reynolds, CJ;
Swadling, L;
Gibbons, JM;
Pade, C;
Jensen, MP;
Diniz, MO;
Schmidt, NM;
... Boyton, RJ; + view all
(2020)
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Thesis
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Lentiviral vector vaccines for T cell-mediated protection against influenza.
Doctoral thesis , UCL (University College London).
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Maini, M;
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Clonal dynamics and turnover in T cell memory.
UNSPECIFIED thesis , UNSPECIFIED.
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Pallett, L;
(2014)
Metabolic regulation of hepatic immunopathology by myeloid-derived suppressor cells.
Doctoral thesis , UCL (University College London).
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