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Number of items: 49.
Article
Blombach, Fabian;
Sýkora, Michal;
Case, Jo;
Feng, Xu;
Baquero, Diana P;
Fouqueau, Thomas;
Phung, Duy Khanh;
... Werner, Finn; + view all
(2024)
Cbp1 and Cren7 form chromatin-like structures that ensure efficient transcription of long CRISPR arrays.
Nature Communications
, 15
, Article 1620. 10.1038/s41467-024-45728-8.
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Blombach, Fabian;
Werner, Finn;
(2024)
Chromatin and gene regulation in archaea.
Molecular Microbiology
10.1111/mmi.15302.
(In press).
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Blum, Matthias;
Andreeva, Antonina;
Florentino, Laise Cavalcanti;
Chuguransky, Sara Rocio;
Grego, Tiago;
Hobbs, Emma;
Pinto, Beatriz Lazaro;
... Bateman, Alex; + view all
(2024)
InterPro: the protein sequence classification resource in 2025.
Nucleic Acids Research
, Article gkae1082. 10.1093/nar/gkae1082.
(In press).
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Bonello, Joseph;
Orengo, Christine;
(2024)
FunPredCATH: An ensemble method for predicting protein function using CATH.
Biochim Biophys Acta Proteins Proteom
, 1872
(2)
, Article 140985. 10.1016/j.bbapap.2023.140985.
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Bradford, HF;
McDonnell, TCR;
Stewart, A;
Skelton, A;
Ng, J;
Baig, Z;
Fraternali, F;
... Mauri, C; + view all
(2024)
Thioredoxin is a metabolic rheostat controlling regulatory B cells.
Nature Immunology
10.1038/s41590-024-01798-w.
(In press).
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Bull, Daniel;
Matte, Julie C;
Navarron, Carmen M;
McIntyre, Rebecca;
Whiting, Paul;
Katan, Matilda;
Ducotterd, Fiona;
(2024)
The hypermorphic PLCγ2 S707Y variant dysregulates microglial cell function – Insight into PLCγ2 activation in brain health and disease, and opportunities for therapeutic modulation.
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
, 1870
(2)
, Article 166978. 10.1016/j.bbadis.2023.166978.
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Bunney, Tom D;
Kampyli, Charis;
Gregory, Ashley;
Katan, Matilda;
(2024)
Characterisation of molecular mechanisms for PLCγ2 disease-linked variants.
Advances in Biological Regulation
, 94
, Article 101053. 10.1016/j.jbior.2024.101053.
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Cameron, George;
Gruszka, Dominika T;
Gruar, Rhian;
Xie, Sherry;
Kaya, Çağla;
Nasmyth, Kim A;
Baxter, Jonathan;
... Yardimci, Hasan; + view all
(2024)
Sister chromatid cohesion establishment during DNA replication termination.
Science
, 384
(6691)
, Article eadf0224. 10.1126/science.adf0224.
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Cheetham, Max J;
Huo, Yunlong;
Stroyakovski, Maria;
Cheng, Li;
Wan, Daniel;
Dell, Anne;
Santini, Joanne M;
(2024)
Specificity and diversity of Klebsiella pneumoniae phage-encoded capsule depolymerases.
Essays in Biochemistry
, 68
(5)
pp. 661-677.
10.1042/ebc20240015.
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Chen, Yu;
Briant, Kit;
Camus, Marine D;
Brodsky, Frances M;
(2024)
Clathrin light chains CLCa and CLCb have non-redundant roles in epithelial lumen formation.
Life Science Alliance
, 7
(1)
, Article e202302175. 10.26508/lsa.202302175.
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Cook, Ryan;
Crisci, Marco A;
Pye, Hannah V;
Telatin, Andrea;
Adriaenssens, Evelien M;
Santini, Joanne M;
(2024)
Decoding huge phage diversity: a taxonomic classification of Lak megaphages.
Journal of General Virology
, 105
(5)
10.1099/jgv.0.001997.
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Costa, Tiago RD;
Patkowski, Jonasz B;
Macé, Kévin;
Christie, Peter J;
Waksman, Gabriel;
(2024)
Structural and functional diversity of type IV secretion systems.
Nature Reviews Microbiology
, 22
pp. 170-185.
10.1038/s41579-023-00974-3.
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Erinjeri, Annmary Paul;
Wang, Xunyan;
Williams, Rhianna;
Chiozzi, Riccardo Zenezini;
Thalassinos, Konstantinos;
Labbadia, Johnathan;
(2024)
HSF-1 promotes longevity through ubiquilin-1-dependent mitochondrial network remodelling.
Nature Communications
, 15
, Article 9797. 10.1038/s41467-024-54136-x.
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Flaherty, Cole C;
Phillips, Ian R;
Janmohamed, Azara;
Shephard, Elizabeth A;
(2024)
Living with trimethylaminuria and body and breath malodour: personal perspectives.
BMC Public Health
, 24
, Article 222. 10.1186/s12889-024-17685-w.
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Grimm, Fiona;
Asuaje, Agustin;
Jain, Aakriti;
Silva dos Santos, Mariana;
Kleinjung, Jens;
Nunes, Patricia M;
Gehrig, Stefanie;
... Anastasiou, Dimitrios; + view all
(2024)
Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia.
EMBO Journal
, 43
(8)
pp. 1545-1569.
10.1038/s44318-024-00065-w.
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Guo, D;
De Sciscio, ML;
Chi-Fung Ng, J;
Fraternali, F;
(2024)
Modelling the assembly and flexibility of antibody structures.
Current Opinion in Structural Biology
, 84
, Article 102757. 10.1016/j.sbi.2023.102757.
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Guo, Dongjun;
Ng, Joseph Chi-Fung;
Dunn-Walters, Deborah K;
Fraternali, Franca;
(2024)
VCAb: a web-tool for structure-guided exploration of antibodies.
Bioinformatics Advances
, 4
(1)
, Article vbae137. 10.1093/bioadv/vbae137.
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Heller, Gabriella T;
Shukla, Vaibhav Kumar;
Figueiredo, Angelo Miguel;
Hansen, D Flemming;
(2024)
Picosecond Dynamics of a Small Molecule in Its Bound State with an Intrinsically Disordered Protein.
Journal of the American Chemical Society
10.1021/jacs.3c11614.
(In press).
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Herling, Therese W;
Cassaignau, Anaïs ME;
Wentink, Anne S;
Peter, Quentin AE;
Kumar, Pavan C;
Kartanas, Tadas;
Schneider, Matthias M;
... Knowles, Tuomas PJ; + view all
(2024)
Thermodynamic profiles for cotranslational trigger factor substrate recognition.
Science Advances
, 10
(28)
, Article eadn4824. 10.1126/sciadv.adn4824.
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Ignatiou, Athanasios;
Macé, Kévin;
Redzej, Adam;
Costa, Tiago RD;
Waksman, Gabriel;
Orlova, Elena V;
(2024)
Structural Analysis of Protein Complexes by Cryo-Electron Microscopy.
Methods in Molecular Biology
, 2715
pp. 431-470.
10.1007/978-1-0716-3445-5_27.
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Kamuda, Kamila;
Ronzoni, Riccardo;
Majumdar, Avik;
Guan, Fiona HX;
Irving, James A;
Lomas, David A;
(2024)
A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate.
The FEBS Journal.
10.1111/febs.17121.
(In press).
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Kipkorir, Terry;
Polgar, Peter;
Barker, Declan;
D’Halluin, Alexandre;
Patel, Zaynah;
Arnvig, Kristine B;
(2024)
A novel regulatory interplay between atypical B12
riboswitches and uORF translation in Mycobacterium
tuberculosis.
Nucleic Acids Research
10.1093/nar/gkae338.
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Lebrusant-Fernandez, Marta;
Ap Rees, Tom;
Jimeno, Rebeca;
Angelis, Nikolaos;
Ng, Joseph C;
Fraternali, Franca;
Li, Vivian SW;
(2024)
IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells.
Cell Reports
, 43
(12)
, Article 114948. 10.1016/j.celrep.2024.114948.
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Lin, W;
Wells, J;
Wang, Z;
Orengo, C;
Martin, ACR;
(2024)
Enhancing missense variant pathogenicity prediction with protein language models using VariPred.
Scientific Reports
, 14
(1)
, Article 8136. 10.1038/s41598-024-51489-7.
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Liu, Chu'nan;
Denzler, Lilian M;
Hood, Oliver EC;
Martin, Andrew CR;
(2024)
Do antibody CDR loops change conformation upon binding?
mAbs
, 16
(1)
, Article 2322533. 10.1080/19420862.2024.2322533.
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Manalastas-Cantos, Karen;
Adoni, Kish R;
Pfeifer, Matthias;
Märtens, Birgit;
Grünewald, Kay;
Thalassinos, Konstantinos;
Topf, Maya;
(2024)
Modeling flexible protein structure with AlphaFold2 and cross-linking mass spectrometry.
Molecular & Cellular Proteomics (MCP)
, 23
(3)
, Article 100724. 10.1016/j.mcpro.2024.100724.
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Martin, Reuben L;
Heifetz, Alexander;
Bodkin, Mike J;
Townsend-Nicholson, Andrea;
(2024)
High-Throughput Structure-Based Drug Design (HT-SBDD) Using Drug Docking, Fragment Molecular Orbital Calculations, and Molecular Dynamic Techniques.
Methods in Molecular Biology
, 2716
pp. 293-306.
10.1007/978-1-0716-3449-3_13.
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Øvreås, Lise;
Kallscheuer, Nicolai;
Calisto, Rita;
Bordin, Nicola;
Storesund, Julia E;
Jogler, Christian;
Devos, Damien;
(2024)
Comparative genomic analyses of aerobic planctomycetes isolated from the deep sea and the ocean surface.
Antonie Van Leeuwenhoek
, 118
, Article 33. 10.1007/s10482-024-02041-0.
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Pettitt, AJ;
Shukla, VK;
Figueiredo, AM;
Newton, LS;
McCarthy, S;
Tabor, AB;
Heller, GT;
... Hansen, DF; + view all
(2024)
An integrative characterization of proline cis and trans conformers in a disordered peptide.
Biophysical Journal
, 123
(21)
pp. 3798-3811.
10.1016/j.bpj.2024.09.028.
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Phung, Duy Khanh;
Pilotto, Simona;
Matelska, Dorota;
Blombach, Fabian;
Pinotsis, Nikos;
Hovan, Ladislav;
Gervasio, Francesco Luigi;
(2024)
Archaeal NusA2 is the ancestor of ribosomal protein eS7 in eukaryotes.
Structure
10.1016/j.str.2024.10.019.
(In press).
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Pilotto, Simona;
Sýkora, Michal;
Cackett, Gwenny;
Dulson, Christopher;
Werner, Finn;
(2024)
Structure of the recombinant RNA polymerase from African Swine Fever Virus.
Nature Communications
, 15
, Article 1606. 10.1038/s41467-024-45842-7.
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Reinisch, I;
Michenthaler, H;
Sulaj, A;
Moyschewitz, E;
Krstic, J;
Galhuber, M;
Xu, R;
... Prokesch, A; + view all
(2024)
Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape.
Nature Communications
, 15
, Article 1391. 10.1038/s41467-024-45724-y.
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Scoglio, GD;
Jackson, HO;
Purton, S;
(2024)
The commercial potential of Aphanizomenon flos-aquae, a nitrogen-fixing edible cyanobacterium.
Journal of Applied Phycology
10.1007/s10811-024-03214-0.
(In press).
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Servius, Lutecia;
Pigoli, Davide;
Ng, Joseph;
Fraternali, Franca;
(2024)
Predicting class switch recombination in B-cells from antibody repertoire data.
Biometrical Journal
, 66
(4)
, Article 2300171. 10.1002/bimj.202300171.
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Singh, Amandeep;
Singh, Vikash;
Wallis, Nadav;
Abis, Giancarlo;
Oberman, Froma;
Wood, Tyler;
Dhamdhere, Mayura;
... Sharma, Arun K; + view all
(2024)
Development of a specific and potent IGF2BP1 inhibitor: A promising therapeutic agent for IGF2BP1-expressing cancers.
European Journal of Medicinal Chemistry
, 263
, Article 115940. 10.1016/j.ejmech.2023.115940.
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Spiteri, Valentina A;
Doutch, James;
Rambo, Robert P;
Bhatt, Jayesh S;
Gor, Jayesh;
Dalby, Paul A;
Perkins, Stephen J;
(2024)
Using atomistic solution scattering modelling to elucidate the role of the Fc glycans in human IgG4.
PLoS One
, 19
(4)
, Article e0300964. 10.1371/journal..
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Streit, Julian O;
Bukvin, Ivana V;
Chan, Sammy HS;
Bashir, Shahzad;
Woodburn, Lauren F;
Włodarski, Tomasz;
Figueiredo, Angelo Miguel;
... Christodoulou, John; + view all
(2024)
The ribosome lowers the entropic penalty of protein folding.
Nature
10.1038/s41586-024-07784-4.
(In press).
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Tossounian, Maria-Armineh;
Zhao, Yuhan;
Yu, Bess Yi Kun;
Markey, Samuel A;
Malanchuk, Oksana;
Zhu, Yuejia;
Cain, Amanda;
(2024)
Low-molecular-weight thiol transferases in redox regulation and antioxidant defence.
Redox Biology
, 71
, Article 103094. 10.1016/j.redox.2024.103094.
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Townsend-Nicholson, Andrea;
(2024)
Teaching Medical Students to Use Supercomputers: A Personal Reflection.
Methods in Molecular Biology
, 2716
pp. 413-420.
10.1007/978-1-0716-3449-3_20.
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Waman, Vaishali P;
Bordin, Nicola;
Alcraft, Rachel;
Vickerstaff, Robert;
Rauer, Clemens;
Chan, Qian;
Sillitoe, Ian;
... Orengo, Christine; + view all
(2024)
CATH 2024: CATH-AlphaFlow Doubles the Number of Structures in CATH and Reveals Nearly 200 New Folds.
Journal of Molecular Biology
, Article 168551. 10.1016/j.jmb.2024.168551.
(In press).
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Waman, Vaishali P;
Bordin, Nicola;
Lau, Andy;
Kandathil, Shaun;
Wells, Jude;
Miller, David;
Velankar, Sameer;
... Orengo, Christine; + view all
(2024)
CATH v4.4: major expansion of CATH by experimental and predicted structural data.
Nucleic Acids Research
, Article gkae1087. 10.1093/nar/gkae1087.
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Waman, VP;
Ashford, P;
Lam, SD;
Sen, N;
Abbasian, M;
Woodridge, L;
Goldtzvik, Y;
... Orengo, CA; + view all
(2024)
Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics.
Scientific Reports
, 14
, Article 14208. 10.1038/s41598-024-61541-1.
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Włodarski, Tomasz;
Streit, Julian O;
Mitropoulou, Alkistis;
Cabrita, Lisa D;
Vendruscolo, Michele;
Christodoulou, John;
(2024)
Bayesian reweighting of biomolecular structural ensembles using heterogeneous cryo-EM maps with the cryoENsemble method.
Scientific Reports
, 14
, Article 18149. 10.1038/s41598-024-68468-7.
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Wong, Katie;
Pitcher, David;
Braddon, Fiona;
Downward, Lewis;
Steenkamp, Retha;
Masoud, Sherry;
Annear, Nicholas;
... Gale, Daniel P; + view all
(2024)
Description and Cross-Sectional Analyses of 25,880 Adults and Children in the UK National Registry of Rare Kidney Diseases Cohort.
Kidney International Reports
, 9
(7)
pp. 2067-2083.
10.1016/j.ekir.2024.04.062.
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Yang, Tangweina;
Filippov, Ivan;
Manathunga, Lakshan;
Baghai, Aria;
Maréchal, Amandine;
Raleigh, Daniel P;
Zhyvoloup, Alexander;
(2024)
On the importance of being amidated: Analysis of the role of the conserved C-terminal amide of amylin in amyloid formation and cytotoxicity.
Biophysical Chemistry
, 307
, Article 107168. 10.1016/j.bpc.2023.107168.
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Thesis
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Boron, Veronica Anna;
(2024)
Analysis of antibody structure using computational methods.
Doctoral thesis (Ph.D), UCL (University College London).
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Casamento, Alessandra;
(2024)
Investigating the regulation of Fast Endophilin-Mediated Endocytosis.
Doctoral thesis (Ph.D), UCL (University College London).
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Kamuda, Kamila;
(2024)
Molecular changes in the cellular landscape elicited by expression of the Z variant α1-antitrypsin.
Doctoral thesis (Ph.D), UCL (University College London).
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Yu, Bess Yi Kun;
(2024)
Elucidating the molecular mechanisms of the antioxidant function of CoA and protein CoAlation.
Doctoral thesis (Ph.D), UCL (University College London).
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