Browse by UCL people
Group by: Type | Date
Number of items: 55.
2025
Ortí, Guillermo;
Peczynski, Christophe;
Boreland, William;
O'Reilly, Maeve;
von Bonin, Malte;
Balduzzi, Adriana;
Besley, Caroline;
... Peric, Zinaida; + view all
(2025)
Graft-versus-host disease after anti-CD19 chimeric antigen receptor T-cell therapy following allogeneic hematopoietic cell transplantation: a transplant complications and paediatric diseases working parties joint EBMT study.
Leukemia
, 39
pp. 431-437.
10.1038/s41375-024-02467-5.
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Yeung, Jenny;
Liao, Aiyin;
Shaw, Matthew;
Silva, Soraia;
Vetharoy, Winston;
Rico, Diego Leon;
Kirby, Ian;
... Amrolia, Persis J; + view all
(2025)
Anti-CD45 PBD-based antibody-drug conjugates are effective targeted conditioning agents for gene therapy and stem cell transplant.
Molecular Therapy
, 32
(6)
pp. 1672-1686.
10.1016/j.ymthe.2024.03.032.
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2024
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De Oliveira Canedo, Gustavo;
Roddie, Claire;
Amrolia, Persis J;
(2024)
Dual targeting CAR-T cells for B-cell acute lymphoblastic leukaemia and B-cell non-Hodgkin lymphoma.
Blood Advances
10.1182/bloodadvances.2024013586.
(In press).
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Gabelli, Maria;
Oporto-Espuelas, Macarena;
Bonney, Denise Kathleen;
Burridge, Saskia;
Farish, Susan;
Mullanfiroze, Khushnuma;
Lazareva, Arina;
... Ghorashian, Sara; + view all
(2024)
Maintenance therapy for early loss of B-cell aplasia after CD19 CAR T-cell therapy.
Blood Advances
, 8
(8)
pp. 1959-1963.
10.1182/bloodadvances.2023011168.
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Ghorashian, Sara;
Lucchini, Giovanna;
Richardson, Rachel;
Nguyen, Kyvi;
Terris, Craig;
Guvenel, Aleks;
Oporto Espuelas, Macarena;
... Amrolia, Persis J; + view all
(2024)
CD19/CD22 targeting with co-transduced CAR T-cells to prevent antigen negative relapse after CAR T-cell therapy of B-ALL.
Blood
, 143
(2)
pp. 118-123.
10.1182/blood.2023020621.
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Lucchini, G;
Cozma, E;
Jackson, A;
Gilmour, K;
Protheroe, R;
Wilson, K;
Peggs, K;
... Amrolia, PJ; + view all
(2024)
COVID-19 infection in adult and paediatric recipients of allogeneic stem cell transplantation: The UK experience.
Leukemia Research
, 147
, Article 107618. 10.1016/j.leukres.2024.107618.
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Mishra, Avijeet Kumar;
Burridge, Saskia;
Espuelas, Macarena Oporto;
O'Reilly, Maeve;
Cummins, Michelle;
Nicholson, Emma;
Wheldon, Sophie;
... Ghorashian, Sara; + view all
(2024)
Practice guideline: Preparation for CAR T-cell therapy in children and young adults with B-acute lymphoblastic leukaemia.
British Journal of Haematology
10.1111/bjh.19381.
(In press).
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2023
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Anderson, Nathaniel D;
Birch, Jack;
Accogli, Theo;
Criado, Ignacio;
Khabirova, Eleonora;
Parks, Conor;
Wood, Yvette;
... Ghorashian, Sara; + view all
(2023)
Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia.
Nature Medicine
10.1038/s41591-023-02415-3.
(In press).
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Gabelli, Maria;
Stepensky, Polina;
Ottaviano, Giorgio;
Mullanfiroze, Khushnuma;
Lazareva, Arina;
Zaidman, Irina;
Even-Or, Ehud;
... Rao, Kanchan; + view all
(2023)
Incremental donor lymphocyte infusion to treat mixed chimerism after allogeneic stem cell transplantation in children with non-malignant diseases.
Bone Marrow Transplantation
, 58
pp. 109-111.
10.1038/s41409-022-01844-x.
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Horgan, Claire;
Mullanfiroze, Khushnuma;
Rauthan, Archana;
Patrick, Katharine;
Butt, Naeem Akram;
Mirci-Danicar, Oana;
O'Connor, Olya;
... Wynn, Robert; + view all
(2023)
T-replete cord transplants give superior outcomes in high risk and relapsed/refractory paediatric myeloid malignancy.
Blood Advances
10.1182/bloodadvances.2022009253.
(In press).
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Lamble, Adam J;
Moskop, Amy;
Pulsipher, Michael A;
Maude, Shannon L;
Summers, Corinne;
Annesley, Colleen;
Baruchel, André;
... Shah, Nirali; + view all
(2023)
INSPIRED Symposium Part 2: Prevention and Management of Relapse Following Chimeric Antigen Receptor T Cell Therapy for B Cell Acute Lymphoblastic Leukemia.
Transplantation and Cellular Therapy
, 29
(11)
pp. 674-684.
10.1016/j.jtct.2023.08.030.
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Lum, SH;
James, B;
Ottaviano, G;
Ewins, AM;
Patrick, K;
Ali, S;
Carpenter, B;
... Wynn, R; + view all
(2023)
Alemtuzumab, Dual Graft-versus-Host Disease Prophylaxis, and Lower CD3+ T Cell Doses Equalize Rates of Acute and Chronic Graft-versus-Host Disease in Pediatric Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation with Matched Unrelated Donor Peripheral Blood Stem Cells or Bone Marrow Grafts.
Transplantation and Cellular Therapy
10.1016/j.jtct.2023.12.005.
(In press).
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Schuetz, Catharina;
Gerke, Julia;
Ege, Markus Johannes;
Walter, Jolan Eszter;
Kusters, Maaike;
Worth, Austen JJ;
Kanakry, Jennifer A;
... Neven, Bénédicte; + view all
(2023)
Hypomorphic RAG deficiency: impact of disease burden on survival and thymic recovery argues for early diagnosis and HSCT.
Blood
, 141
(7)
pp. 713-724.
10.1182/blood.2022017667.
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2022
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Gabelli, M;
Ademokun, C;
Cooper, N;
Amrolia, PI;
(2022)
Pathogenesis, risk factors and therapeutic options for autoimmune haemolytic anaemia in the post-transplant setting.
British Journal of Haematology
, 196
(1)
pp. 45-62.
10.1111/bjh.17648.
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Kania, Soumya P;
Silva, Juliana MF;
Charles, Oscar J;
Booth, John;
Cheung, SY Amy;
Yates, James WT;
Worth, Austen;
... Standing, Joseph F; + view all
(2022)
Epstein-Barr Virus Reactivation After Paediatric Haematopoietic Stem Cell Transplantation: Risk Factors and Sensitivity Analysis of Mathematical Model.
Frontiers in Immunology
, 13
, Article 903063. 10.3389/fimmu.2022.903063.
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Locatelli, F;
Thompson, AA;
Kwiatkowski, JL;
Porter, JB;
Thrasher, AJ;
Hongeng, S;
Sauer, MG;
... Walters, MC; + view all
(2022)
Betibeglogene Autotemcel Gene Therapy for Non-β⁰/β⁰ Genotype β-Thalassemia.
New England Journal of Medicine
, 386
pp. 415-427.
10.1056/NEJMoa2113206.
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Michelozzi, Ilaria M;
Gomez-Castaneda, Eduardo;
Pohle, Ruben VC;
Cardoso Rodriguez, Ferran;
Sufi, Jahangir;
Puigdevall-Costa, Pau;
Subramaniyam, Meera;
... Giustacchini, Alice; + view all
(2022)
Activation priming and cytokine polyfunctionality modulate the enhanced functionality of low-affinity CD19 CAR T cells.
Blood Advances
10.1182/bloodadvances.2022008490.
(In press).
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Mullanfiroze, Khushnuma;
Lazareva, Arina;
Chu, Jan;
Williams, Lindsey;
Burridge, Saskia;
M Furtado Silva, Juliana;
Chiesa, Robert;
... Amrolia, Persis Jal; + view all
(2022)
CD34^{+}-selected stem cell boost can safely improve cytopenias following CAR-T therapy.
Blood Advances
, 6
(16)
10.1182/bloodadvances.2022007572.
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2021
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Bernard, F;
Uppungunduri, CRS;
Meyer, S;
Cummins, M;
Patrick, K;
James, B;
Skinner, R;
... UK Paediatric BMT group, .; + view all
(2021)
Excellent overall and chronic graft-versus-host-disease-free event-free survival in Fanconi anaemia patients undergoing matched related- and unrelated-donor bone marrow transplantation using alemtuzumab–Flu–Cy: the UK experience.
British Journal of Haematology
, 193
(4)
pp. 804-813.
10.1111/bjh.17418.
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Biasco, L;
Izotova, N;
Rivat, C;
Ghorashian, S;
Richardson, R;
Guvenel, A;
Hough, R;
... Amrolia, PJ; + view all
(2021)
Clonal expansion of T memory stem cells determines early anti-leukemic responses and long-term CAR T cell persistence in patients.
Nature Cancer
, 2
pp. 629-64.
10.1038/s43018-021-00207-7.
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Cordoba, S;
Onuoha, S;
Thomas, S;
Pignataro, DS;
Hough, R;
Ghorashian, S;
Vora, A;
... Amrolia, PJ; + view all
(2021)
CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial.
Nature Medicine
, 27
pp. 1797-1805.
10.1038/s41591-021-01497-1.
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Ottaviano, G;
Achini-Gutzwiller, F;
Kalwak, K;
Lanino, E;
Faraci, M;
Rao, K;
Chiesa, R;
... Lucchini, G; + view all
(2021)
Impact of in Vivo Lymphodepletion on Outcome in Children with Nonmalignant Disorders Receiving Peripheral Blood Stem Cell Transplantation.
Transplantation and Cellular Therapy
, 27
(12)
1020.e1-1020.e5.
10.1016/j.jtct.2021.08.015.
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Ottaviano, G;
Baird, S;
Bonney, D;
Connor, P;
Cummins, M;
Evans, P;
Gibson, B;
... Vora, A; + view all
(2021)
The role of immunotherapy in relapse/refractory precursor-B acute lymphoblastic leukaemia: real-life UK/Ireland experience in children and young adults.
British Journal of Haematology
, 192
(2)
e42-e44.
10.1111/bjh.17198.
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Sharma, A;
Huang, S;
Li, Y;
Brooke, RJ;
Ahmed, I;
Allewelt, HB;
Amrolia, P;
... Triplett, BM; + view all
(2021)
Outcomes of pediatric patients with therapy-related myeloid neoplasms.
Bone Marrow Transplantation
, 56
pp. 2997-3007.
10.1038/s41409-021-01448-x.
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Venturini, C;
Houldcroft, CJ;
Lazareva, A;
Wegner, F;
Morfopoulou, S;
Amrolia, PJ;
Golwala, Z;
... Breuer, J; + view all
(2021)
Epstein-Barr virus (EBV) deletions as biomarkers of response to treatment of chronic active EBV.
British Journal of Haematology
10.1111/bjh.17790.
(In press).
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Veys, D;
Amrolia, P;
Vora, A;
Veys, P;
Rao, A;
Gattens, M;
(2021)
The Role of Blood and Marrow Transplantation in Treating Pediatric Chronic Myelogenous Leukaemia in the Era of Tyrosine Kinase Inhibitors.
Biology of Blood and Marrow Transplantation
, 27
(1)
pp. 96-97.
10.1016/j.bbmt.2020.10.011.
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2020
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Elfeky, R;
Lucchini, G;
Lum, S-H;
Ottaviano, G;
Builes, N;
Nademi, Z;
Battersby, A;
... Veys, P; + view all
(2020)
New insights into risk factors for transplant-associated thrombotic microangiopathy in pediatric HSCT.
Blood Advances
, 4
(11)
pp. 2418-2429.
10.1182/bloodadvances.2019001315.
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Ottaviano, G;
Lucchini, G;
Breuer, J;
Furtado-Silva, JM;
Lazareva, A;
Ciocarlie, O;
Elfeky, R;
... Chiesa, R; + view all
(2020)
Delaying haematopoietic stem cell transplantation in children with viral respiratory infections reduces transplant-related mortality.
British Journal of Haematology
, 188
(4)
pp. 560-569.
10.1111/bjh.16216.
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Veys, D;
Norton, A;
Ainsworth, JR;
Amrolia, P;
Lucchini, G;
(2020)
Isolated Intraocular Relapse of Pediatric B-cell Precursor Acute Lymphoblastic Leukaemia Following Chimeric Antigen Receptor T-lymphocyte Therapy.
Cureus
, 12
(10)
, Article e10937. 10.7759/cureus.10937.
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2019
|
Chiesa, R;
Standing, JF;
Winter, R;
Nademi, Z;
Chu, J;
Pinner, D;
Kloprogge, F;
... Slatter, M; + view all
(2019)
Proposed therapeutic range of treosulfan in reduced toxicity pediatric allogeneic hematopoietic stem cell transplant conditioning: results from a prospective trial.
Clinical Pharmacology & Therapeutics
10.1002/cpt.1715.
(In press).
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Elfeky, R;
Shah, RM;
Unni, MN;
Ottaviano, G;
Rao, K;
Chiesa, R;
Amrolia, P;
... Veys, P; + view all
(2019)
New graft manipulation strategies improved outcome of mismatched stem cell transplantation in children with primary immunodeficiencies.
Journal of Allergy and Clinical Immunology
, 144
(1)
pp. 280-293.
10.1016/j.jaci.2019.01.030.
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Ghorashian, S;
Kramer, AM;
Onuoha, S;
Wright, G;
Bartram, J;
Richardson, R;
Albon, SJ;
... Amrolia, PJ; + view all
(2019)
Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR.
Nature Medicine
, 25
pp. 1408-1414.
10.1038/s41591-019-0549-5.
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2018
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Elfeky, RA;
Furtado-Silva, JM;
Chiesa, R;
Rao, K;
Amrolia, P;
Lucchini, G;
Gilmour, K;
... Veys, P; + view all
(2018)
One hundred percent survival after transplantation of 34 patients with Wiskott-Aldrich syndrome over 20 years.
[Letter].
Journal of Allergy and Clinical Immunology
, 142
(5)
1654-1656.e7.
10.1016/j.jaci.2018.06.042.
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Elfeky, RA;
Furtado-Silva, JM;
Chiesa, R;
Rao, K;
Lucchini, G;
Amrolia, P;
Worth, A;
... Veys, P; + view all
(2018)
Umbilical cord blood transplantation without in vivo T-cell depletion for children with MHC class II deficiency.
Journal of Allergy and Clinical Immunology
, 141
(6)
2279-2282.e2.
10.1016/j.jaci.2017.10.051.
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Gassas, A;
Sivaprakasam, P;
Cummins, M;
Breslin, P;
Patrick, K;
Slatter, M;
Skinner, R;
... Amrolia, P; + view all
(2018)
High transplant-related mortality associated with haematopoietic stem cell transplantation for paediatric therapy-related acute myeloid leukaemia (t-AML). A study on behalf of the United Kingdom Paediatric Blood and Bone Marrow Transplant Group.
Bone Marrow Transplantation
, 53
(9)
pp. 1165-1169.
10.1038/s41409-018-0157-x.
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Ghorashian, S;
Amrolia, P;
Veys, P;
(2018)
Open access? Widening access to chimeric antigen receptor (CAR) therapy for ALL.
Experimental Hematology
, 66
pp. 5-16.
10.1016/j.exphem.2018.07.002.
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Ip, W;
Silva, JMF;
Gaspar, H;
Mitra, A;
Patel, S;
Rao, K;
Chiesa, R;
... Qasim, W; + view all
(2018)
Multicenter phase 1/2 application of adenovirus-specific T cells in high-risk pediatric patients after allogeneic stem cell transplantation.
Cytotherapy
, 20
(6)
pp. 830-838.
10.1016/j.jcyt.2018.03.040.
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Lucchini, G;
Marsh, R;
Gilmour, K;
Worth, A;
Nademi, Z;
Rao, A;
Booth, C;
... Rao, K; + view all
(2018)
Treatment dilemmas in asymptomatic children with primary hemophagocytic lymphohistiocytosis.
Blood
, 132
(19)
pp. 2088-2096.
10.1182/blood-2018-01-827485.
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M F Silva, J;
Ladomenou, F;
Carpenter, B;
Chandra, S;
Sedlacek, P;
Formankova, R;
Grandage, V;
... Veys, P; + view all
(2018)
Allogeneic hematopoietic stem cell transplantation for severe, refractory juvenile idiopathic arthritis.
Blood Adv
, 2
(7)
pp. 777-786.
10.1182/bloodadvances.2017014449.
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Slatter, MA;
Rao, K;
Abd Hamid, IJ;
Nademi, Z;
Chiesa, R;
Elfeky, R;
Pearce, MS;
... Veys, P; + view all
(2018)
Treosulfan, Fludarabine Conditioning for HSCT in Children with Primary Immunodeficiency: UK Experience.
Biology of Blood and Marrow Transplantation
, 24
(3)
pp. 529-536.
10.1016/j.bbmt.2017.11.009.
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Unni, MNM;
Elfeky, R;
Rao, K;
Nademi, Z;
Chiesa, R;
Amrolia, P;
Skinner, R;
... Slatter, MA; + view all
(2018)
Non-posttransplant lymphoproliferative disorder malignancy after hematopoietic stem cell transplantation in patients with primary immunodeficiency: UK experience.
Journal of Allergy and Clinical Immunology
, 141
(6)
2319-2321.e1.
10.1016/j.jaci.2018.02.038.
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2017
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Goodship, THJ;
Pinto, F;
Weston-Davies, WH;
Silva, J;
Nishimura, J-I;
Nunn, MA;
Mackie, I;
... Veys, P; + view all
(2017)
Use of the complement inhibitor Coversin to treat HSCT-associated TMA.
Blood Advances
, 1
(16)
pp. 1254-1258.
10.1182/bloodadvances.2016002832.
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Hiwarkar, P;
Amrolia, P;
Sivaprakasam, P;
Lum, SH;
Doss, H;
O'Rafferty, C;
Petterson, T;
... United Kingdom Paediatric Bone Marrow Transplant Group; + view all
(2017)
Brincidofovir is highly efficacious in controlling adenoviremia in pediatric recipients of hematopoietic cell transplant.
Blood
, 129
(14)
pp. 2033-2037.
10.1182/blood-2016-11-749721.
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Hiwarkar, P;
Hubank, M;
Qasim, W;
Chiesa, R;
Gilmour, KC;
Saudemont, A;
Amrolia, PJ;
(2017)
Cord blood transplantation recapitulates fetal ontogeny with a distinct molecular signature that supports CD4+ T-cell reconstitution.
Blood Advances
, 1
(24)
pp. 2206-2216.
10.1182/bloodadvances.2017010827.
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Kramer, AM;
(2017)
Delineating the impact of binding-domain affinity and kinetic properties on Chimeric Antigen Receptor T-cell function.
Doctoral thesis , UCL (University College London).
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Qasim, W;
Zhan, H;
Samarasinghe, S;
Adams, S;
Amrolia, P;
Stafford, S;
Butler, K;
... Veys, P; + view all
(2017)
Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells.
Science Translational Medicine
, 9
(374)
, Article eaaj2013. 10.1126/scitranslmed.aaj2013.
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Rossig, C;
Pule, M;
Altvater, B;
Saiagh, S;
Wright, G;
Ghorashian, S;
Clifton-Hadley, L;
... Amrolia, PJ; + view all
(2017)
Vaccination to improve the persistence of CD19CAR gene-modified T cells in relapsed pediatric acute lymphoblastic leukemia.
Leukemia
, 31
pp. 1087-1095.
10.1038/leu.2017.39.
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2016
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Kammermeier, J;
Lucchini, G;
Pai, SY;
Worth, A;
Rampling, D;
Amrolia, P;
Silva, J;
... Veys, P; + view all
(2016)
Stem cell transplantation for tetratricopeptide repeat domain 7A deficiency: long-term follow-up.
Blood
, 128
(9)
pp. 1306-1308.
10.1182/blood-2016-01-696385.
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Morgenstern, DA;
Ahsan, G;
Brocklesby, M;
Ings, S;
Balsa, C;
Veys, P;
Brock, P;
... Watts, MJ; + view all
(2016)
Post-thaw viability of cryopreserved peripheral blood stem cells (PBSC) does not guarantee functional activity: important implications for quality assurance of stem cell transplant programmes.
British Journal of Haematology
, 174
(6)
pp. 942-951.
10.1111/bjh.14160.
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Rao, K;
Adams, S;
Qasim, W;
Allwood, Z;
Worth, A;
Silva, J;
Lucchini, G;
... Amrolia, P; + view all
(2016)
Effect of stem cell source on long-term chimerism and event-free survival in children with primary immunodeficiency disorders after fludarabine and melphalan conditioning regimen.
Journal of Allergy and Clinical Immunology
, 138
(4)
pp. 1152-1160.
10.1016/j.jaci.2016.01.053.
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Soheili, T;
Rivière, J;
Ricciardelli, I;
Durand, A;
Verhoeyen, E;
Derrien, AC;
Lagresle-Peyrou, C;
... Cavazzana, M; + view all
(2016)
Gene-corrected human Munc13-4-deficient CD8+ T-cells can efficiently restrict EBV-driven lymphoproliferation in immunodeficient mice.
Blood
, 128
(24)
pp. 2859-2862.
10.1182/blood-2016-07-729871.
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Straathof, K;
Anoop, P;
Allwood, Z;
Silva, J;
Nikolajeva, O;
Chiesa, R;
Veys, P;
... Rao, K; + view all
(2016)
Long-term outcome following cyclosporine-related neurotoxicity in paediatric allogeneic haematopoietic stem cell transplantation.
Bone Marrow Transplant
, 52
pp. 159-162.
10.1038/bmt.2016.232.
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2014
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Hassan, A;
Lee, P;
Maggina, P;
Xu, JH;
Moreira, D;
Slatter, M;
Nademi, Z;
... Qasim, W; + view all
(2014)
Host natural killer immunity is a key indicator of permissiveness for donor cell engraftment in patients with severe combined immunodeficiency.
Journal of Allergy and Clinical Immunology
, 133
(6)
pp. 1660-1666.
10.1016/j.jaci.2014.02.042.
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Ricciardelli, I;
Blundell, MP;
Brewin, J;
Thrasher, A;
Pule, M;
Amrolia, PJ;
(2014)
Towards gene therapy for EBV-associated posttransplant lymphoma with genetically modified EBV-specific cytotoxic T cells.
Blood
, 124
(16)
pp. 2514-2522.
10.1182/blood-2014-01-553362.
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2013
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Ricciardelli, I;
Brewin, J;
Lugthart, G;
Albon, SJ;
Pule, M;
Amrolia, PJ;
(2013)
Rapid Generation of EBV-Specific Cytotoxic T Lymphocytes Resistant to Calcineurin Inhibitors for Adoptive Immunotherapy.
Am J Transplant
, 13
(12)
3244 - 3252.
10.1111/ajt.12475.
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