Browse by UCL people
Group by: Type | Date
Number of items: 92.
2026
Nijjar, S;
Kastora, S;
Bajrami, A;
Solangon, S;
Widschwendter, M;
Jurkovic, D;
(2026)
Endometrial assessment in abnormal uterine bleeding: transvaginal ultrasound alone may not be good enough.
Ultrasound in Obstetrics & Gynecology
, 67
(1)
, Article uog.70126. 10.1002/uog.70126.
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2024
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Haran, Shaun;
Chindera, Kantaraja;
Sabry, May;
Wilkinson, Nafisa;
Arora, Rupali;
Zubiak, Agnieszka;
Bartlett, Thomas E;
... Widschwendter, Martin; + view all
(2024)
Natural Killer Cell Dysfunction in Premenopausal BRCA1 Mutation Carriers: A Potential Mechanism for Ovarian Carcinogenesis.
Cancers
, 16
(6)
, Article 1186. 10.3390/cancers16061186.
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Illah, Ojone;
Scott, Malcolm;
Redl, Elisa;
Barrett, James E;
Schreiberhuber, Lena;
Herzog, Chiara;
Vavourakis, Charlotte D;
... Widschwendter, Martin; + view all
(2024)
High performance of the DNA methylation-based WID-qEC
test for detecting uterine cancers independent of
sampling modalities.
International Journal of Cancer
10.1002/ijc.35000.
(In press).
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Newton, Claire;
Graham, Radha;
Liberale, Viola;
Burnell, Matthew;
Menon, Usha;
Mould, Tim;
Olaitan, Adeola;
... Manchanda, Ranjit; + view all
(2024)
Outcomes of minimal access retroperitoneal para-aortic lymphadenectomy in patients with locally advanced cervical cancer.
Journal of Obstetrics and Gynaecology
, 44
(1)
, Article 2344529. 10.1080/01443615.2024.2344529.
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Saner, Flurina AM;
Takahashi, Kazuaki;
Budden, Timothy;
Pandey, Ahwan;
Ariyaratne, Dinuka;
Zwimpfer, Tibor A;
Meagher, Nicola S;
... Garsed, Dale W; + view all
(2024)
Concurrent RB1 Loss and BRCA-Deficiency Predicts Enhanced Immunological Response and Long-Term Survival in Tubo-Ovarian High-Grade Serous Carcinoma.
Clinical Cancer Research
10.1158/1078-0432.CCR-23-3552.
(In press).
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2023
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Barrett, James E;
Jones, Allison;
Evans, Iona;
Herzog, Chiara;
Reisel, Daniel;
Olaitan, Adeola;
Mould, Tim;
... Widschwendter, Martin; + view all
(2023)
The WID-EC test for the detection and risk prediction of endometrial cancer.
International Journal of Cancer
, 152
(9)
pp. 1731-2015.
10.1002/ijc.34406.
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Herzog, Chiara;
Jones, Allison;
Evans, Iona;
Reisel, Daniel;
Olaitan, Adeola;
Doufekas, Konstantinos;
MacDonald, Nicola;
... Widschwendter, Martin; + view all
(2023)
Plasma cell-free DNA methylation analysis for ovarian cancer detection: Analysis of samples from a case-control study and an ovarian cancer screening tria.
International Journal of Cancer
10.1002/ijc.34757.
(In press).
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Herzog, Chiara;
Jones, Allison;
Evans, Iona;
Zikan, Michal;
Cibula, David;
Harbeck, Nadia;
Colombo, Nicoletta;
... Widschwendter, Martin; + view all
(2023)
DNA methylation at quantitative trait loci (mQTLs) varies with cell type and nonheritable factors and may improve breast cancer risk assessment.
npj Precision Oncology
, 7
, Article 99. 10.1038/s41698-023-00452-2.
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Herzog, Chiara;
Vavourakis, Charlotte D;
Barrett, James E;
Karbon, Gerlinde;
Villunger, Andreas;
Wang, Jiangrong;
Sundström, Karin;
... Widschwendter, Martin; + view all
(2023)
HPV-induced host epigenetic reprogramming is lost upon progression to high-grade cervical intraepithelial neoplasia.
International Journal of Cancer
, 152
(11)
pp. 2225-2237.
10.1002/ijc.34477.
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Köbel, Martin;
Kang, Eun-Young;
Weir, Ashley;
Rambau, Peter F;
Lee, Cheng-Han;
Nelson, Gregg S;
Ghatage, Prafull;
... Brenton, James D; + view all
(2023)
p53 and ovarian carcinoma survival: an Ovarian Tumor Tissue Analysis consortium study.
Journal of Pathology: Clinical Research
10.1002/cjp2.311.
(In press).
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Lehtinen, Matti;
Pimenoff, Ville N;
Nedjai, Belinda;
Louvanto, Karolina;
Verhoef, Lisanne;
Heideman, Daniëlle AM;
El-Zein, Mariam;
... Dillner, Joakim; + view all
(2023)
Assessing the risk of cervical neoplasia in the post-HPV vaccination era.
International Journal of Cancer
, 152
(6)
pp. 1060-1068.
10.1002/ijc.34286.
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Meagher, NS;
Hamilton, P;
Milne, K;
Thornton, S;
Harris, B;
Weir, A;
Alsop, J;
... Ramus, SJ; + view all
(2023)
Profiling the immune landscape in mucinous ovarian carcinoma.
Gynecologic Oncology
, 168
pp. 23-31.
10.1016/j.ygyno.2022.10.022.
(In press).
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Moqri, Mahdi;
Herzog, Chiara;
Poganik, Jesse R;
Biomarkers of Aging Consortium;
Justice, Jamie;
Belsky, Daniel W;
Higgins-Chen, Albert;
... Gladyshev, Vadim N; + view all
(2023)
Biomarkers of aging for the identification and evaluation of longevity interventions.
Cell
, 186
(18)
pp. 3758-3775.
10.1016/j.cell.2023.08.003.
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Schreiberhuber, Lena;
Herzog, Chiara;
Vavourakis, Charlotte D;
Redl, Elisa;
Kastner, Christine;
Jones, Allison;
Evans, Iona;
... Widschwendter, Martin; + view all
(2023)
The WID-qEC test: Performance in a hospital-based cohort and feasibility to detect endometrial and cervical cancers.
International Journal of Cancer
, 152
(6)
pp. 1269-1274.
10.1002/ijc.34275.
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Wang, Chen;
Block, Matthew S;
Cunningham, Julie M;
Sherman, Mark E;
McCauley, Bryan M;
Armasu, Sebastian M;
Vierkant, Robert A;
... Goode, Ellen L; + view all
(2023)
Methylation Signature Implicated in Immuno-Suppressive Activities in Tubo-Ovarian High-Grade Serous Carcinoma.
Cancer Epidemiology, Biomarkers and Prevention
, 32
(4)
pp. 542-549.
10.1158/1055-9965.EPI-22-0941.
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2022
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Barrett, James E;
Herzog, Chiara;
Jones, Allison;
Leavy, Olivia C;
Evans, Iona;
Knapp, Susanne;
Reisel, Daniel;
... Widschwendter, Martin; + view all
(2022)
The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples.
Nature Communications
, 13
(1)
, Article 449. 10.1038/s41467-021-27918-w.
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Barrett, James E;
Herzog, Chiara;
Kim, Yoo-Na;
Bartlett, Thomas E;
Jones, Allison;
Evans, Iona;
Cibula, David;
... Widschwendter, Martin; + view all
(2022)
Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock.
Genome Biology
, 23
(1)
, Article 52. 10.1186/s13059-022-02603-3.
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Barrett, James E;
Sundström, Karin;
Jones, Allison;
Evans, Iona;
Wang, Jiangrong;
Herzog, Chiara;
Dillner, Joakim;
(2022)
The WID-CIN test identifies women with, and at risk of, cervical intraepithelial neoplasia grade 3 and invasive cervical cancer.
Genome Medicine
, 14
, Article 116. 10.1186/s13073-022-01116-9.
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Bartlett, Thomas E;
Evans, Iona;
Jones, Allison;
Barrett, James E;
Haran, Shaun;
Reisel, Daniel;
Papaikonomou, Kiriaki;
... Widschwendter, Martin; + view all
(2022)
Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women.
Genome Medicine
, 14
, Article 64. 10.1186/s13073-022-01063-5.
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Heinze, K;
Nazeran, TM;
Lee, S;
Krämer, P;
Cairns, ES;
Chiu, DS;
Leung, SCY;
... Anglesio, MS; + view all
(2022)
Validated biomarker assays confirm ARID1A loss is confounded with MMR deficiency, CD8 TIL infiltration, and provides no independent prognostic value in endometriosis-associated ovarian carcinomas.
The Journal of Pathology
, 26
(4)
pp. 388-401.
10.1002/path.5849.
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Herzog, Chiara;
Marín, Fátima;
Jones, Allison;
Evans, Iona;
Reisel, Daniel;
Redl, Elisa;
Schreiberhuber, Lena;
... Widschwendter, Martin; + view all
(2022)
A Simple Cervicovaginal Epigenetic Test for Screening and Rapid Triage of Women With Suspected Endometrial Cancer: Validation in Several Cohort and Case/Control Sets.
Journal of Clinical Oncology
10.1200/JCO.22.00266.
(In press).
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Herzog, Chiara;
Sundström, Karin;
Jones, Allison;
Evans, Iona;
Barrett, James E;
Wang, Jiangrong;
Redl, Elisa;
... Widschwendter, Martin; + view all
(2022)
DNA methylation-based detection and prediction of cervical intraepithelial neoplasia grade 3 and invasive cervical cancer with the WID™-qCIN test.
Clinical Epigenetics
, 14
, Article 150. 10.1186/s13148-022-01353-0.
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Van der Kolk, WL;
Van der Zee, AGJ;
Slomovitz, BM;
Baldwin, PJW;
Van Doorn, HC;
De Hullu, JA;
Van der Velden, J;
... Van Le, L; + view all
(2022)
Unilateral inguinofemoral lymphadenectomy in patients with early-stage vulvar squamous cell carcinoma and a unilateral metastatic sentinel lymph node is safe.
Gynecologic Oncology
, 167
(1)
pp. 3-10.
10.1016/j.ygyno.2022.07.017.
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Weir, Ashley;
Kang, Eun-Young;
Meagher, Nicola S;
Nelson, Gregg S;
Ghatage, Prafull;
Lee, Cheng-Han;
Riggan, Marjorie J;
... Ramus, Susan J; + view all
(2022)
Increased FOXJ1 protein expression is associated with improved overall survival in high-grade serous ovarian carcinoma: an Ovarian Tumor Tissue Analysis Consortium Study.
British Journal of Cancer
10.1038/s41416-022-02014-y.
(In press).
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2021
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Kalsi, JK;
Ryan, A;
Gentry-Maharaj, A;
Margolin-Crump, D;
Singh, N;
Burnell, M;
Benjamin, E;
... Menon, U; + view all
(2021)
Completeness and accuracy of national cancer and death registration for outcome ascertainment in trials—an ovarian cancer exemplar.
Trials
, 22
, Article 88. 10.1186/s13063-020-04968-x.
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Mühlberger, N;
Sroczynski, G;
Gogollari, A;
Jahn, B;
Pashayan, N;
Steyerberg, E;
Widschwendter, M;
(2021)
Cost effectiveness of breast cancer screening and prevention: a systematic review with a focus on risk-adapted strategies.
The European Journal of Health Economics
, 22
pp. 1311-1344.
10.1007/s10198-021-01338-5.
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Oonk, MHM;
Slomovitz, B;
Baldwin, PJW;
van Doorn, HC;
van der Velden, J;
de Hullu, JA;
Gaarenstroom, KN;
... van der Zee, AGJ; + view all
(2021)
Radiotherapy Versus Inguinofemoral Lymphadenectomy as Treatment for Vulvar Cancer Patients With Micrometastases in the Sentinel Node: Results of GROINSS-V II.
Journal of Clinical Oncology
10.1200/jco.21.00006.
(In press).
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2020
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Bolt, I;
Bunnik, EM;
Tromp, K;
Pashayan, N;
Widschwendter, M;
de Beaufort, I;
(2020)
Prevention in the age of personal responsibility: epigenetic risk-predictive screening for female cancers as a case study.
Journal of Medical Ethics
10.1136/medethics-2020-106146.
(In press).
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Dilley, J;
Burnell, M;
Gentry-Maharaj, A;
Ryan, A;
Neophytou, C;
Apostolidou, S;
Karpinskyj, C;
... Menon, U; + view all
(2020)
Ovarian cancer symptoms, routes to diagnosis and survival – Population cohort study in the ‘no screen’ arm of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).
Gynecologic Oncology
10.1016/j.ygyno.2020.05.002.
(In press).
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Millstein, J;
Budden, T;
Goode, EL;
Anglesio, MS;
Talhouk, A;
Intermaggio, MP;
Leong, HS;
... Ramus, SJ; + view all
(2020)
Prognostic gene expression signature for high-grade serous ovarian cancer.
Annals of Oncology
10.1016/j.annonc.2020.05.019.
(In press).
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Nené, NR;
Barrett, J;
Jones, A;
Evans, I;
Reisel, D;
Timms, JF;
Paprotka, T;
... Widschwendter, M; + view all
(2020)
DNA methylation signatures to predict the cervicovaginal microbiome status.
Clinical Epigenetics
, 12
(1)
, Article 180. 10.1186/s13148-020-00966-7.
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Pashayan, N;
Antoniou, AC;
Ivanus, U;
Esserman, LJ;
Easton, DF;
French, D;
Sroczynski, G;
... Widschwendter, M; + view all
(2020)
Personalized early detection and prevention of breast cancer: ENVISION consensus statement.
Nature Reviews Clinical Oncology
, 17
pp. 687-705.
10.1038/s41571-020-0388-9.
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Sroczynski, G;
Gogollari, A;
Kuehne, F;
Hallsson, LR;
Widschwendter, M;
Pashayan, N;
Siebert, U;
(2020)
A Systematic Review On Cost-effectiveness Studies Evaluating Ovarian Cancer Early Detection And Prevention Strategies.
Cancer Prevention Research
, 13
(5)
pp. 429-442.
10.1158/1940-6207.CAPR-19-0506.
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Talhouk, A;
George, J;
Wang, C;
Budden, T;
Tan, TZ;
Chiu, DS;
Kommoss, S;
... Anglesio, MS; + view all
(2020)
Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).
Clinical Cancer Research
, 26
(20)
pp. 5411-5423.
10.1158/1078-0432.CCR-20-0103.
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Widschwendter, M;
Dubeau, L;
(2020)
Non-Surgical Cancer Risk Reduction in BRCA1 Mutation Carriers: Disabling the Remote Control.
Cancers
, 12
(3)
, Article 547. 10.3390/cancers12030547.
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2019
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Lévesque, E;
Kirby, E;
Bolt, I;
Knoppers, BM;
de Beaufort, I;
Pashayan, N;
Widschwendter, M;
(2019)
Ethical, Legal, and Regulatory Issues for the Implementation of Omics-Based Risk Prediction of Women's Cancer: Points to Consider.
Public Health Genomics
, 21
(1-2)
pp. 37-44.
10.1159/000492663.
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Meagher, NS;
Wang, L;
Rambau, PF;
Intermaggio, MP;
Huntsman, DG;
Wilkens, LR;
El-Bahrawy, MA;
... Köbel, M; + view all
(2019)
A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases.
Modern Pathology
, 32
pp. 1834-1846.
10.1038/s41379-019-0302-0.
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Nene, NR;
Reisel, D;
Leimbach, A;
Franchi, D;
Jones, A;
Evans, I;
Knapp, S;
... Widschwendter, M; + view all
(2019)
Association between the cervicovaginal microbiome, BRCA1 mutation status, and risk of ovarian cancer: a case-control study.
Lancet Oncology
, 20
(8)
pp. 1171-1182.
10.1016/S1470-2045(19)30340-7.
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Rebitschek, FG;
Pashayan, N;
Widschwendter, M;
Wegwarth, O;
(2019)
Do cancer risk and benefit-harm ratios influence women's consideration of risk-reducing mastectomy? A scenario-based experiment in five European countries.
PLoS One
, 14
(6)
, Article e0218188. 10.1371/journal.pone.0218188.
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Wegwarth, O;
Pashayan, N;
Widschwendter, M;
Rebitschek, FG;
(2019)
Women's perception, attitudes, and intended behavior towards predictive epigenetic risk testing for female cancers in 5 European countries: a cross-sectional online survey.
BMC Public Health
, 19
, Article 667. 10.1186/s12889-019-6994-8.
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2018
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Gao, Y;
Widschwendter, M;
Teschendorff, AE;
(2018)
DNA Methylation Patterns in Normal Tissue Correlate more Strongly with Breast Cancer Status than Copy-Number Variants.
EBioMedicine
10.1016/j.ebiom.2018.04.025.
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Lawn, RB;
Anderson, EL;
Suderman, M;
Simpkin, AJ;
Gaunt, TR;
Teschendorff, AE;
Widschwendter, M;
... Howe, LD; + view all
(2018)
Psychosocial adversity and socioeconomic position during childhood and epigenetic age: analysis of two prospective cohort studies.
Human Molecular Genetics
, 27
(7)
pp. 1301-1308.
10.1093/hmg/ddy036.
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Nunes, N;
Ambler, G;
Foo, X;
Widschwendter, M;
Jurkovic, D;
(2018)
A prospective evaluation of the IOTA Logistic Regression Models (LR1 and LR2) in comparison to Subjective Pattern Recognition for the diagnosis of ovarian cancer in the outpatient setting.
Ultrasound in Obstetrics & Gynecology
, 51
(6)
pp. 829-835.
10.1002/uog.18918.
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Pashayan, N;
(2018)
Prediction models for endometrial cancer for the general population or symptomatic women: a systematic review.
Critical Reviews in Oncology/Hematology
, 126
pp. 92-99.
10.1016/j.critrevonc.2018.03.023.
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Rambau, PF;
Vierkant, RA;
Intermaggio, MP;
Kelemen, LE;
Goodman, MT;
Herpel, E;
Pharoah, PD;
... Köbel, M; + view all
(2018)
Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study.
The Journal of Pathology: Clinical Research
, 4
(4)
pp. 250-261.
10.1002/cjp2.109.
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Wegwarth, O;
Widschwendter, M;
Cibula, D;
Sundström, K;
Portuesi, R;
Lein, I;
Rebitschek, FG;
(2018)
What do European women know about their female cancer risks and cancer screening? A cross-sectional online intervention survey in five European countries.
BMJ Open
, 8
(12)
, Article e023789. 10.1136/bmjopen-2018-023789.
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Widschwendter, M;
Jones, A;
Evans, I;
Reisel, D;
Dillner, J;
Sundström, K;
Steyerberg, EW;
... FORECEE (4C) Consortium, .; + view all
(2018)
Epigenome-based cancer risk prediction: rationale, opportunities and challenges.
Nature Reviews Clinical Oncology
, 15
pp. 292-309.
10.1038/nrclinonc.2018.30.
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Zheng, SC;
Webster, AP;
Dong, D;
Feber, A;
Graham, DG;
Sullivan, R;
Jevons, S;
... Teschendorff, AE; + view all
(2018)
A novel cell-type deconvolution algorithm reveals substantial contamination by immune cells in saliva, buccal and cervix.
Epigenomics
, 10
(7)
pp. 925-940.
10.2217/epi-2018-0037.
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2017
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Chen, Y;
Widschwendter, M;
Teschendorff, AE;
(2017)
Systems-epigenomics inference of transcription factor activity implicates aryl-hydrocarbon-receptor inactivation as a key event in lung cancer development.
Genome Biology
, 18
, Article 236. 10.1186/s13059-017-1366-0.
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Goode, EL;
Block, MS;
Kalli, KR;
Vierkant, RA;
Chen, W;
Fogarty, ZC;
Gentry-Maharaj, A;
... Ramus, SJ; + view all
(2017)
Dose-Response Association of CD8(+) Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer.
JAMA Oncology
, 3
(12)
, Article e173290. 10.1001/jamaoncol.2017.3290.
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Hoo, WL;
(2017)
Does ovarian suspension during laparoscopic surgery for endometriosis reduce postoperative adhesions? A randomised controlled trial.
Masters thesis , UCL (University College London).
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Kazarian, A;
Blyuss, O;
Metodieva, G;
Gentry-Maharaj, A;
Ryan, A;
Kiseleva, EM;
Prytomanova, OM;
... Timms, JF; + view all
(2017)
Testing breast cancer serum biomarkers for early detection and prognosis in pre-diagnosis samples.
British Journal of Cancer
, 116
pp. 501-508.
10.1038/bjc.2016.433.
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Kiechl, S;
Schramek, D;
Widschwendter, M;
Fourkala, EO;
Zaikin, A;
Jones, A;
Jaeger, B;
... Penninger, JM; + view all
(2017)
Aberrant regulation of RANKL/OPG in women at high risk of developing breast cancer.
Oncotarget
, 8
(2)
pp. 2477-2484.
10.18632/oncotarget.14013.
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Marchetti, C;
Kristeleit, R;
McCormack, M;
Mould, T;
Olaitan, A;
Widschwendter, M;
MacDonald, N;
(2017)
Outcome of patients with advanced ovarian cancer who do not undergo debulking surgery: A single institution retrospective review.
Gynecologic Oncology
, 144
(1)
pp. 57-60.
10.1016/j.ygyno.2016.11.001.
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Milani, A;
Kristeleit, R;
McCormack, M;
Raja, F;
Luvero, D;
Widschwendter, M;
MacDonald, N;
... Ledermann, JA; + view all
(2017)
Switching from standard to dose-dense chemotherapy in front-line treatment of advanced ovarian cancer: a retrospective study of feasibility and efficacy.
ESMO Open
, 1
(6)
, Article e000117. 10.1136/esmoopen-2016-000117.
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Nunes, N;
Ambler, G;
Foo, X;
Naftalin, J;
Derdelis, G;
Widschwendter, M;
Jurkovic, D;
(2017)
Comparison of two protocols for the management of asymptomatic postmenopausal women with adnexal tumours - a randomised controlled trial of RMI/RCOG vs Simple Rules.
British Journal of Cancer
, 116
pp. 584-591.
10.1038/bjc.2017.17.
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Ong, J-S;
Hwang, L-D;
Cuellar-Partida, G;
Martin, NG;
Chenevix-Trench, G;
Quinn, MCJ;
Cornelis, MC;
... Ovarian Cancer Association Consortium; + view all
(2017)
Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study.
International Journal of Epidemiology
, 47
(2)
pp. 450-459.
10.1093/ije/dyx236.
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Simpkin, AJ;
Cooper, R;
Howe, LD;
Relton, CL;
Davey Smith, G;
Teschendorff, A;
Widschwendter, M;
... Hardy, R; + view all
(2017)
Are objective measures of physical capability related to accelerated epigenetic age? Findings from a British birth cohort.
BMJ Open
, 7
(10)
, Article e016708. 10.1136/bmjopen-2017-016708.
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Tomar, T;
Alkema, NG;
Schreuder, L;
Meersma, GJ;
de Meyer, T;
van Criekinge, W;
Klip, HG;
... Wisman, GBA; + view all
(2017)
Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer.
BMC Med
, 15
(1)
, Article 116. 10.1186/s12916-017-0870-0.
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Widschwendter, M;
Evans, I;
Jones, A;
Ghazali, S;
Reisel, D;
Ryan, A;
Gentry-Maharaj, A;
... Lempiainen, H; + view all
(2017)
Methylation patterns in serum DNA for early identification of disseminated breast cancer.
Genome Medicine
, 9
, Article 115. 10.1186/s13073-017-0499-9.
|
|
|
Widschwendter, M;
Zikan, M;
Wahl, B;
Lempiainen, H;
Paprotka, T;
Evans, I;
Jones, A;
... Wittenberger, T; + view all
(2017)
The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer.
Genome Medicine
, 9
, Article 116. 10.1186/s13073-017-0500-7.
|
|
2016
|
Bartlett, TE;
Chindera, K;
McDermott, J;
Breeze, CE;
Cooke, WR;
Jones, A;
Reisel, D;
... Widschwendter, M; + view all
(2016)
Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution.
Nature Communications
, 7
, Article ARTN 116. 10.1038/ncomms11620.
|
|
|
Gao, Y;
Jones, A;
Fasching, PA;
Ruebner, M;
Beckmann, MW;
Widschwendter, M;
Teschendorff, AE;
(2016)
The integrative epigenomic-transcriptomic landscape of ER positive breast cancer (vol 7, 126, 2015).
Clinical Epigenetics
, 8
, Article 63. 10.1186/s13148-016-0231-4.
|
|
Jacobs, IJ;
Menon, U;
Ryan, A;
Gentry-Maharaj, A;
Burnell, M;
Kalsi, JK;
Amso, NN;
... Skates, SJ; + view all
(2016)
Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial.
Lancet
, 387
(10022)
pp. 945-956.
10.1016/S0140-6736(15)01224-6.
|
|
Kalwa, M;
Hänzelmann, S;
Otto, S;
Kuo, CC;
Franzen, J;
Joussen, S;
Fernandez-Rebollo, E;
... Wagner, W; + view all
(2016)
The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation.
Nucleic Acids Research
, 44
(22)
pp. 10631-10643.
10.1093/nar/gkw802.
|
|
|
Lemech, CR;
Ensell, L;
Paterson, JC;
Eminowicz, G;
Lowe, H;
Arora, R;
Arkenau, H-T;
... Kristeleit, RS; + view all
(2016)
Enumeration and Molecular Characterisation of Circulating Tumour Cells in Endometrial Cancer.
Oncology
, 91
(1)
pp. 48-54.
10.1159/000445999.
|
|
Levine, ME;
Lu, AT;
Chen, BH;
Hernandez, DG;
Singleton, AB;
Ferrucci, L;
Bandinelli, S;
... Horvath, S; + view all
(2016)
Menopause accelerates biological aging.
Proceedings of the National Academy of Sciences of the United States of America
, 113
(33)
pp. 9327-9332.
10.1073/pnas.1604558113.
|
|
|
Lim, A;
Mesher, D;
Gentry-Maharaj, A;
Balogun, N;
Widschwendter, M;
Jacobs, I;
Sasieni, P;
(2016)
Time to diagnosis of Type I or II invasive epithelial ovarian cancers: a multicentre observational study using patient questionnaire and primary care records.
BJOG - An International Journal Of Obstetrics And Gynaecology
, 123
(6)
pp. 1012-1020.
10.1111/1471-0528.13447.
|
|
|
Pashayan, N;
Reisel, D;
Widschwendter, M;
(2016)
Integration of genetic and epigenetic markers for risk stratification: opportunities and challenges.
Personalized Medicine
, 13
(2)
pp. 93-95.
10.2217/pme.15.53.
|
|
Teschendorff, AE;
Jones, A;
Widschwendter, M;
(2016)
Stochastic epigenetic outliers can define field defects in cancer.
BMC Bioinformatics
, 17
, Article 178. 10.1186/s12859-016-1056-z.
|
|
|
Teschendorff, AE;
Zheng, SC;
Feber, A;
Yang, Z;
Beck, S;
Widschwendter, M;
(2016)
The multi-omic landscape of transcription factor inactivation in cancer.
Genome Medicine
, 8
, Article 89. 10.1186/s13073-016-0342-8.
|
|
|
Yang, Z;
Wong, A;
Kuh, D;
Paul, DS;
Rakyan, VK;
Leslie, RD;
Zheng, SC;
... Teschendorff, AE; + view all
(2016)
Correlation of an epigenetic mitotic clock with cancer risk.
GENOME BIOLOGY
, 17
(ARTN 205)
10.1186/s13059-016-1064-3.
|
|
2015
|
Bartlett, TE;
Jones, A;
Goode, EL;
Fridley, BL;
Cunningham, JM;
Berns, EM;
Wik, E;
... Widschwendter, M; + view all
(2015)
Intra-gene DNA methylation variability is a clinically independent prognostic marker in women's cancers.
PLoS One
, 10
(12)
, Article e0143178. 10.1371/journal.pone.0143178.
|
|
|
Menon, U;
Ryan, A;
Kalsi, J;
Gentry-Maharaj, A;
Dawnay, A;
Habib, M;
Apostolidou, S;
... Jacobs, I; + view all
(2015)
Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening.
Journal of Clinical Oncology
, 33
(18)
pp. 2062-2071.
10.1200/JCO.2014.59.4945.
|
|
|
Paul, DS;
Jones, A;
Sellar, RS;
Mayor, NP;
Feber, A;
Webster, AP;
Afonso, N;
... Beck, S; + view all
(2015)
A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation.
Genome Medicine
, 7
(1)
, Article 128. 10.1186/s13073-015-0246-z.
|
|
|
Teschendorff, AE;
Lee, SH;
Jones, A;
Fiegl, H;
Kalwa, M;
Wagner, W;
Chindera, K;
... Widschwendter, M; + view all
(2015)
HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer.
Genome Medicine
, 7
(1)
, Article 108. 10.1186/s13073-015-0233-4.
|
|
|
Widschwendter, M;
Burnell, M;
Fraser, L;
Rosenthal, AN;
Philpott, S;
Reisel, D;
Dubeau, L;
... Dougall, WC; + view all
(2015)
Osteoprotegerin (OPG), the endogenous inhibitor of receptor activator of NF-κB ligand (RANKL), is dysregulated in BRCA mutation carriers.
EBioMedicine
, 2
(10)
pp. 1331-1339.
10.1016/j.ebiom.2015.08.037.
|
2014
|
Almouzni, G;
Altucci, L;
Amati, B;
Ashley, N;
Baulcombe, D;
Beaujean, N;
Bock, C;
... Widschwendter, M; + view all
(2014)
Relationship between genome and epigenome - challenges and requirements for future research.
BMC Genomics
, 15
(1)
, Article 15:487. 10.1186/1471-2164-15-487.
|
|
|
Anjum, S;
Fourkala, EO;
Zikan, M;
Wong, A;
Gentry-Maharaj, A;
Jones, A;
Hardy, R;
... Widschwendter, M; + view all
(2014)
A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival.
Genome Med
, 6
(6)
47 -.
10.1186/gm567.
|
|
|
Teschendorff, AE;
Liu, X;
Caren, H;
Pollard, SM;
Beck, S;
Widschwendter, M;
Chen, L;
(2014)
The dynamics of DNA methylation covariation patterns in carcinogenesis.
PLoS Comput Biol
, 10
(7)
, Article e1003709. 10.1371/journal.pcbi.1003709.
|
|
|
Wittenberger, T;
Sleigh, S;
Reisel, D;
Zikan, M;
Wahl, B;
Alunni-Fabbroni, M;
Jones, A;
... Widschwendter, M; + view all
(2014)
DNA methylation markers for early detection of women's cancer: promise and challenges.
Epigenomics
, 6
(3)
311 - 327.
10.2217/epi.14.20.
|
|
2013
|
Bartlett, TE;
Zaikin, A;
Olhede, SC;
West, J;
Teschendorff, AE;
Widschwendter, M;
(2013)
Corruption of the Intra-Gene DNA Methylation Architecture Is a Hallmark of Cancer.
PLoS One
, 8
(7)
, Article e68285. 10.1371/journal.pone.0068285.
|
|
|
Jones, A;
Teschendorff, AE;
Li, Q;
Hayward, JD;
Kannan, A;
Mould, T;
West, J;
... Widschwendter, M; + view all
(2013)
Role of DNA Methylation and Epigenetic Silencing of HAND2 in Endometrial Cancer Development.
PLoS Med
, 10
(11)
, Article e1001551. 10.1371/journal.pmed.1001551.
|
|
|
West, J;
Widschwendter, M;
Teschendorff, AE;
(2013)
Distinctive topology of age-associated epigenetic drift in the human interactome.
PNAS (Proceedings of the National Academy of Sciences of the United States of America)
, 110
(35)
pp. 14138-14143.
10.1073/pnas.1307242110.
|
|
|
Widschwendter, M;
Rosenthal, AN;
Philpott, S;
Rizzuto, I;
Fraser, L;
Hayward, J;
Fourkala, EO;
... Dubeau, L; + view all
(2013)
The sex hormone system in carriers of BRCA1/2 mutations: A case-control study.
The Lancet Oncology
, 14
(12)
1226 - 1232.
10.1016/S1470-2045(13)70448-0.
|
|
2012
|
Fourkala, EO;
Gentry-Maharaj, A;
Burnell, M;
Ryan, A;
Manchanda, R;
Dawnay, A;
Jacobs, I;
... Menon, U; + view all
(2012)
Histological confirmation of breast cancer registration and self-reporting in England and Wales: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening.
British Journal of Cancer
, 106
(12)
1910 -1916.
10.1038/bjc.2012.155.
|
|
|
Zhuang, J;
Jones, A;
Lee, SH;
Ng, E;
Fiegl, H;
Zikan, M;
Cibula, D;
... Widschwendter, M; + view all
(2012)
The dynamics and prognostic potential of DNA methylation changes at stem cell gene loci in women's cancer.
PLoS Genetics
, 8
(2)
, Article e1002517. 10.1371/journal.pgen.1002517.
|
|
2011
|
Campan, M;
Moffitt, M;
Houshdaran, S;
Shen, H;
Widschwendter, M;
Daxenbichler, G;
Long, T;
... Laird, PW; + view all
(2011)
Genome-scale screen for DNA methylation-based detection markers for ovarian cancer.
PLOS One
, 6
(12)
, Article e28141. 10.1371/journal.pone.0028141.
|
|
2010
|
del Rincon, SV;
Rogers, J;
Widschwendter, M;
Sun, DH;
Sieburg, HB;
Spruck, C;
(2010)
Development and Validation of a Method for Profiling Post-Translational Modification Activities Using Protein Microarrays.
PLOS ONE
, 5
(6)
, Article e11332. 10.1371/journal.pone.0011332.
|
|
2009
|
Teschendorff, AE;
Menon, U;
Gentry-Maharaj, A;
Ramus, SJ;
Gayther, SA;
Apostolidou, S;
Jones, A;
... Widschwendter, M; + view all
(2009)
An Epigenetic Signature in Peripheral Blood Predicts Active Ovarian Cancer.
PLOS ONE
, 4
(12)
, Article e8274. 10.1371/journal.pone.0008274.
|
|
2008
|
Widschwendter, M;
Apostolidou, S;
Raum, E;
Rothenbacher, D;
Fiegl, H;
Menon, U;
Stegmaier, C;
... Brenner, H; + view all
(2008)
Epigenotyping in Peripheral Blood Cell DNA and Breast Cancer Risk: A Proof of Principle Study.
PLOS ONE
, 3
(7)
, Article e2656. 10.1371/journal.pone.0002656.
|
|
|
Widschwendter, M;
Apostolidou, S;
Raum, E;
Rothenbacher, D;
Fiegl, H;
Menon, U;
Stegmaier, C;
... Brenner, H; + view all
(2008)
Epigenotyping in peripheral blood cell DNA and breast cancer risk: A proof of principle study.
PLoS ONE
, 3
(7)
, Article e2656. 10.1371/journal.pone.0002656.
|
|
