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Number of items: 134.

Article

Akhtar, S; Grizenkova, J; Wenborn, A; Hummerich, H; Fernandez de Marco, M; Brandner, S; Collinge, J; Akhtar, S; Grizenkova, J; Wenborn, A; Hummerich, H; Fernandez de Marco, M; Brandner, S; Collinge, J; Lloyd, SE; - view fewer (2013) Sod1 deficiency reduces incubation time in mouse models of prion disease. PLoS One , 8 (1) , Article e54454. 10.1371/journal.pone.0054454.

Akhtar, S; Wenborn, A; Brandner, S; Collinge, J; Lloyd, SE; (2011) Sex effects in mouse prion disease incubation time. PLOS One , 6 (12) , Article e28741. 10.1371/journal.pone.0028741.

Asante, EA; Grimshaw, A; Smidak, M; Jakubcova, T; Tomlinson, A; Jeelani, A; Hamdan, S; ... Collinge, J; + view all Asante, EA; Grimshaw, A; Smidak, M; Jakubcova, T; Tomlinson, A; Jeelani, A; Hamdan, S; Powell, C; Joiner, S; Linehan, JM; Brandner, S; Wadsworth, JDF; Collinge, J; - view fewer (2015) Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS. PLOS Pathogens , 11 (7) , Article e1004953. 10.1371/journal.ppat.1004953.

Asante, EA; Linehan, JM; Smidak, M; Tomlinson, A; Grimshaw, A; Jeelani, A; Jakubcova, T; ... Collinge, J; + view all Asante, EA; Linehan, JM; Smidak, M; Tomlinson, A; Grimshaw, A; Jeelani, A; Jakubcova, T; Hamdan, S; Powell, C; Brandner, S; Wadsworth, JD; Collinge, J; - view fewer (2013) Inherited Prion Disease A117V Is Not Simply a Proteinopathy but Produces Prions Transmissible to Transgenic Mice Expressing Homologous Prion Protein. PLoS Pathog , 9 (9) , Article e1003643. 10.1371/journal.ppat.1003643.

Asante, EA; Linehan, JM; Tomlinson, AD; Jakubcova, T; Hamdan, S; Grimshaw, A; Smidak, M; ... Collinge, J; + view all Asante, EA; Linehan, JM; Tomlinson, AD; Jakubcova, T; Hamdan, S; Grimshaw, A; Smidak, M; Jeelani, A; Nihat, A; Mead, S; Brandner, S; Wadsworth, JDF; Collinge, J; - view fewer (2020) Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS. PLOS Biology , 18 (6) , Article e3000725. 10.1371/journal.pbio.3000725.

Asante, EA; Smidak, M; Grimshaw, A; Houghton, R; Tomlinson, A; Jeelani, A; Jakubcova, T; ... Collinge, J; + view all Asante, EA; Smidak, M; Grimshaw, A; Houghton, R; Tomlinson, A; Jeelani, A; Jakubcova, T; Hamdan, S; Richard-Londt, A; Linehan, JM; Brandner, S; Alpers, M; Whitfield, J; Mead, S; Wadsworth, JDF; Collinge, J; - view fewer (2015) A naturally occurring variant of the human prion protein completely prevents prion disease. Nature , 522 pp. 478-481. 10.1038/nature14510.

Balendra, R; Uphill, J; Collinson, C; Druyeh, R; Adamson, G; Hummerich, H; Zerr, I; ... Mead, S; + view all Balendra, R; Uphill, J; Collinson, C; Druyeh, R; Adamson, G; Hummerich, H; Zerr, I; Gambetti, P; Collinge, J; Mead, S; - view fewer (2016) Variants of PLCXD3 are not associated with variant or sporadic Creutzfeldt-Jakob disease in a large international study. BMC Medical Genetics , 17 , Article 28. 10.1186/s12881-016-0278-2.

Banerjee, G; Farmer, SF; Hyare, H; Jaunmuktane, Z; Mead, S; Ryan, NS; Schott, JM; ... Collinge, J; + view all Banerjee, G; Farmer, SF; Hyare, H; Jaunmuktane, Z; Mead, S; Ryan, NS; Schott, JM; Werring, DJ; Rudge, P; Collinge, J; - view fewer (2024) Iatrogenic Alzheimer’s disease in recipients of cadaveric pituitary-derived growth hormone. Nature Medicine 10.1038/s41591-023-02729-2. (In press).

Benilova, I; Reilly, M; Terry, C; Wenborn, A; Schmidt, C; Marinho, AT; Risse, E; ... Collinge, J; + view all Benilova, I; Reilly, M; Terry, C; Wenborn, A; Schmidt, C; Marinho, AT; Risse, E; Al-Doujaily, H; Wiggins De Oliveira, M; Sandberg, MK; Wadsworth, JDF; Jat, PS; Collinge, J; - view fewer (2020) Highly infectious prions are not directly neurotoxic. Proceeding of the National Academy of Sciences of the United States of America 10.1073/pnas.2007406117. (In press).

Bonham, LW; Karch, CM; Fan, CC; Tan, C; Geier, EG; Wang, Y; Wen, N; ... International Genomics of Alzheimer’s Project (IGAP); + view all Bonham, LW; Karch, CM; Fan, CC; Tan, C; Geier, EG; Wang, Y; Wen, N; Broce, IJ; Li, Y; Barkovich, MJ; Ferrari, R; Hardy, J; Momeni, P; Höglinger, G; Müller, U; Hess, CP; Sugrue, LP; Dillon, WP; Schellenberg, GD; Miller, BL; Andreassen, OA; Dale, AM; Barkovich, AJ; Yokoyama, JS; Desikan, RS; International FTD-Genomics Consortium (IFGC); International Parkinson’s Disease Genetics Consortium (IPDGC); International Genomics of Alzheimer’s Project (IGAP); - view fewer (2018) CXCR4 involvement in neurodegenerative diseases. Translational Psychiatry , 8 (1) , Article 73. 10.1038/s41398-017-0049-7.

Bonham, LW; Steele, NZR; Karch, CM; Broce, I; Geier, EG; Wen, NL; Momeni, P; ... International FTD-Genomics Consortium (IFGC), .; + view all Bonham, LW; Steele, NZR; Karch, CM; Broce, I; Geier, EG; Wen, NL; Momeni, P; Hardy, J; Miller, ZA; Gorno-Tempini, ML; Hess, CP; Lewis, P; Miller, BL; Seeley, WW; Manzoni, C; Desikan, RS; Baranzini, SE; Ferrari, R; Yokoyama, JS; International FTD-Genomics Consortium (IFGC), .; - view fewer (2019) Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia. Scientific Reports , 9 , Article 10854. 10.1038/s41598-019-46415-1.

Broce, I; Karch, CM; Wen, N; Fan, CC; Wang, Y; Tan, CH; Kouri, N; ... Sugrue, LP; + view all Broce, I; Karch, CM; Wen, N; Fan, CC; Wang, Y; Tan, CH; Kouri, N; Ross, OA; Hoeglinger, GU; Muller, U; Hardy, J; Momeni, P; Hess, CP; Dillon, WP; Miller, ZA; Bonham, LW; Rabinovici, GD; Rosen, HJ; Schellenberg, GD; Franke, A; Karlsen, TH; Veldink, JH; Ferrari, R; Yokoyama, JS; Miller, BL; Andreassen, OA; Dale, AM; Desikan, RS; Sugrue, LP; - view fewer (2018) Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. PLoS Medicine , 15 (1) , Article e1002487. 10.1371/journal.pmed.1002487.

Brown, CA; Schmidt, C; Poulter, M; Hummerich, H; Klöhn, PC; Jat, P; Mead, S; ... Lloyd, SE; + view all Brown, CA; Schmidt, C; Poulter, M; Hummerich, H; Klöhn, PC; Jat, P; Mead, S; Collinge, J; Lloyd, SE; - view fewer (2014) In-vitro screen of prion disease susceptibility genes using the scrapie cell assay. Hum Mol Genet , 23 (19) pp. 5102-5108. 10.1093/hmg/ddu233.

C Dabin, L; Guntoro, F; Campbell, T; Bélicard, T; Smith, AR; Smith, RG; Raybould, R; ... Viré, E; + view all C Dabin, L; Guntoro, F; Campbell, T; Bélicard, T; Smith, AR; Smith, RG; Raybould, R; Schott, JM; Lunnon, K; Sarkies, P; Collinge, J; Mead, S; Viré, E; - view fewer (2020) Altered DNA methylation profiles in blood from patients with sporadic Creutzfeldt–Jakob disease. Acta Neuropathologica 10.1007/s00401-020-02224-9. (In press).

Caine, D; Nihat, A; Crabb, P; Rudge, P; Cipolotti, L; Collinge, J; Mead, S; (2018) The language disorder of prion disease is characteristic of a dynamic aphasia and is rarely an isolated clinical feature. PLoS One , 13 (1) , Article e0190818. 10.1371/journal.pone.0190818.

Caine, D; Tinelli, RJ; Hyare, H; De Vita, E; Lowe, J; Lukic, A; Thompson, A; ... Mead, S; + view all Caine, D; Tinelli, RJ; Hyare, H; De Vita, E; Lowe, J; Lukic, A; Thompson, A; Porter, MC; Cipolotti, L; Rudge, P; Collinge, J; Mead, S; - view fewer (2015) The cognitive profile of prion disease: a prospective clinical and imaging study. Ann Clin Transl Neurol , 2 (5) pp. 548-558. 10.1002/acn3.195.

Canas, LS; Sudre, CH; De Vita, E; Nihat, A; Mok, TH; Slattery, CF; Paterson, RW; ... Modat, M; + view all Canas, LS; Sudre, CH; De Vita, E; Nihat, A; Mok, TH; Slattery, CF; Paterson, RW; Foulkes, AJM; Hyare, H; Cardoso, MJ; Thornton, J; Schott, JM; Barkhof, F; Collinge, J; Ourselin, S; Mead, S; Modat, M; - view fewer (2019) Prion disease diagnosis using subject-specific imaging biomarkers within a multi-kernel Gaussian process. NeuroImage: Clinical , Article 102051. 10.1016/j.nicl.2019.102051. (In press).

Castro-Seoane, R; Hummerich, H; Sweeting, T; Tattum, MH; Linehan, JM; Fernandez de Marco, M; Brandner, S; ... Klöhn, PC; + view all Castro-Seoane, R; Hummerich, H; Sweeting, T; Tattum, MH; Linehan, JM; Fernandez de Marco, M; Brandner, S; Collinge, J; Klöhn, PC; - view fewer (2012) Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection. PLoS Pathogens , 8 (2) , Article e1002538. 10.1371/journal.ppat.1002538.

Chia, R; Tattum, MH; Jones, S; Collinge, J; Fisher, EMC; Jackson, GS; (2010) Superoxide Dismutase 1 and tgSOD1(G93A) Mouse Spinal Cord Seed Fibrils, Suggesting a Propagative Cell Death Mechanism in Amyotrophic Lateral Sclerosis. PLOS ONE , 5 (5) , Article e10627. 10.1371/journal.pone.0010627.

Clayton, EL; Mancuso, R; Nielsen, TT; Mizielinska, S; Holmes, H; Powell, N; Norona, F; ... Isaacs, AM; + view all Clayton, EL; Mancuso, R; Nielsen, TT; Mizielinska, S; Holmes, H; Powell, N; Norona, F; Overgaard Larsen, J; Milioto, C; Wilson, KM; Lythgoe, MF; Ourselin, S; Nielsen, JE; Johannsen, P; Holm, I; Collinge, J; Frej, A; Oliver, PL; Gomez-Nicola, D; Isaacs, AM; - view fewer (2017) Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation. Human Molecular Genetics , 26 (5) pp. 873-887. 10.1093/hmg/ddx003.

Clayton, EL; Milioto, C; Muralidharan, B; Norona, FE; Edgar, JR; Soriano, A; Jafar-Nejad, P; ... Isaacs, AM; + view all Clayton, EL; Milioto, C; Muralidharan, B; Norona, FE; Edgar, JR; Soriano, A; Jafar-Nejad, P; Rigo, F; Collinge, J; Isaacs, AM; - view fewer (2018) Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown. Brain , 141 (12) pp. 3428-3442. 10.1093/brain/awy284.

Clayton, EL; Mizielinska, S; Edgar, JR; Nielsen, TT; Marshall, S; Norona, FE; Robbins, M; ... Isaacs, AM; + view all Clayton, EL; Mizielinska, S; Edgar, JR; Nielsen, TT; Marshall, S; Norona, FE; Robbins, M; Damirji, H; Holm, IE; Johannsen, P; Nielsen, JE; Asante, EA; Collinge, J; FReJA consortium, .; Isaacs, AM; - view fewer (2015) Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology. Acta Neuropathologica , 130 (4) pp. 511-523. 10.1007/s00401-015-1475-3.

Collinge, J; Jaunmuktane, Z; Mead, S; Rudge, P; Brandner, S; (2016) Collinge et al. reply. [Rapid communication]. Nature , 537 E7-E9. 10.1038/nature19087.

Collinge, J; Jaunmuktane, Z; Mead, S; Rudge, P; Brandner, S; (2016) Collinge et al. reply. [Rapid communication]. Nature , 535 E2-E3. 10.1038/nature18603.

Collinge, J; Purro, SA; Nicoll, A; (2018) Prion Protein as a Toxic Acceptor of Amyloid-β Oligomers. Biological Psychiatry , 83 (4) pp. 358-368. 10.1016/j.biopsych.2017.11.020.

Corbett, GT; Wang, Z; Hong, W; Colom-Cadena, M; Rose, J; Liao, M; Asfaw, A; ... Walsh, DM; + view all Corbett, GT; Wang, Z; Hong, W; Colom-Cadena, M; Rose, J; Liao, M; Asfaw, A; Hall, TC; Ding, L; DeSousa, A; Frosch, MP; Collinge, J; Harris, DA; Perkinton, MS; Spires-Jones, TL; Young-Pearse, TL; Billinton, A; Walsh, DM; - view fewer (2019) PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins. Acta Neuropathologica 10.1007/s00401-019-02114-9. (In press).

Corbie, Rosie; Campbell, Tracy; Darwent, Lee; Rudge, Peter; Collinge, John; Mead, Simon; (2022) Estimation of the number of inherited prion disease mutation carriers in the UK. European Journal of Human Genetics 10.1038/s41431-022-01132-8. (In press).

D'Castro, L; Wenborn, A; Gros, N; Joiner, S; Cronier, S; Collinge, J; Wadsworth, JDF; (2010) Isolation of Proteinase K-Sensitive Prions Using Pronase E and Phosphotungstic Acid. PLOS ONE , 5 (12) , Article e15679. 10.1371/journal.pone.0015679.

De Vita, E; Ridgway, GR; White, MJ; Porter, MC; Caine, D; Rudge, P; Collinge, J; ... Hyare, H; + view all De Vita, E; Ridgway, GR; White, MJ; Porter, MC; Caine, D; Rudge, P; Collinge, J; Yousry, TA; Jager, HR; Mead, S; Thornton, JS; Hyare, H; - view fewer (2017) Neuroanatomical correlates of prion disease progression - a 3T longitudinal voxel-based morphometry study. NeuroImage: Clinical , 13 pp. 89-96. 10.1016/j.nicl.2016.10.021.

Eisenmenger, L; Porter, MC; Carswell, CJ; Thompson, A; Mead, S; Rudge, P; Collinge, J; ... Hyare, H; + view all Eisenmenger, L; Porter, MC; Carswell, CJ; Thompson, A; Mead, S; Rudge, P; Collinge, J; Brandner, S; Jäger, HR; Hyare, H; - view fewer (2016) Evolution of Diffusion-Weighted Magnetic Resonance Imaging Signal Abnormality in Sporadic Creutzfeldt-Jakob Disease, With Histopathological Correlation. JAMA Neurology , 73 (1) pp. 76-84. 10.1001/jamaneurol.2015.3159.

Escott-Price, V; Bellenguez, C; Wang, LS; Choi, SH; Harold, D; Jones, L; Holmans, P; ... Cardiovascular Health Study (CHS); + view all Escott-Price, V; Bellenguez, C; Wang, LS; Choi, SH; Harold, D; Jones, L; Holmans, P; Gerrish, A; Vedernikov, A; Richards, A; DeStefano, AL; Lambert, JC; Ibrahim-Verbaas, CA; Naj, AC; Sims, R; Jun, G; Bis, JC; Beecham, GW; Grenier-Boley, B; Russo, G; Thornton-Wells, TA; Denning, N; Smith, AV; Chouraki, V; Thomas, C; Ikram, MA; Zelenika, D; Vardarajan, BN; Kamatani, Y; Lin, CF; Schmidt, H; Kunkle, B; Dunstan, ML; Vronskaya, M; United Kingdom Brain Expression Consortium; Johnson, AD; Ruiz, A; Bihoreau, MT; Reitz, C; Pasquier, F; Hollingworth, P; Hanon, O; Fitzpatrick, AL; Buxbaum, JD; Campion, D; Crane, PK; Baldwin, C; Becker, T; Gudnason, V; Cruchaga, C; Craig, D; Amin, N; Berr, C; Lopez, OL; De Jager, PL; Deramecourt, V; Johnston, JA; Evans, D; Lovestone, S; Letenneur, L; Hernández, I; Rubinsztein, DC; Eiriksdottir, G; Sleegers, K; Goate, AM; Fiévet, N; Huentelman, MJ; Gill, M; Brown, K; Kamboh, MI; Keller, L; Barberger-Gateau, P; McGuinness, B; Larson, EB; Myers, AJ; Dufouil, C; Todd, S; Wallon, D; Love, S; Rogaeva, E; Gallacher, J; George-Hyslop, PS; Clarimon, J; Lleo, A; Bayer, A; Tsuang, DW; Yu, L; Tsolaki, M; Bossù, P; Spalletta, G; Proitsi, P; Collinge, J; Sorbi, S; Garcia, FS; Fox, NC; Hardy, J; Naranjo, MC; Bosco, P; Clarke, R; Brayne, C; Galimberti, D; Scarpini, E; Bonuccelli, U; Mancuso, M; Siciliano, G; Moebus, S; Mecocci, P; Zompo, MD; Maier, W; Hampel, H; Pilotto, A; Frank-García, A; Panza, F; Solfrizzi, V; Caffarra, P; Nacmias, B; Perry, W; Mayhaus, M; Lannfelt, L; Hakonarson, H; Pichler, S; Carrasquillo, MM; Ingelsson, M; Beekly, D; Alvarez, V; Zou, F; Valladares, O; Younkin, SG; Coto, E; Hamilton-Nelson, KL; Gu, W; Razquin, C; Pastor, P; Mateo, I; Owen, MJ; Faber, KM; Jonsson, PV; Combarros, O; O'Donovan, MC; Cantwell, LB; Soininen, H; Blacker, D; Mead, S; Mosley, TH; Bennett, DA; Harris, TB; Fratiglioni, L; Holmes, C; de Bruijn, RF; Passmore, P; Montine, TJ; Bettens, K; Rotter, JI; Brice, A; Morgan, K; Foroud, TM; Kukull, WA; Hannequin, D; Powell, JF; Nalls, MA; Ritchie, K; Lunetta, KL; Kauwe, JS; Boerwinkle, E; Riemenschneider, M; Boada, M; Hiltunen, M; Martin, ER; Schmidt, R; Rujescu, D; Dartigues, JF; Mayeux, R; Tzourio, C; Hofman, A; Nöthen, MM; Graff, C; Psaty, BM; Haines, JL; Lathrop, M; Pericak-Vance, MA; Launer, LJ; Van Broeckhoven, C; Farrer, LA; van Duijn, CM; Ramirez, A; Seshadri, S; Schellenberg, GD; Amouyel, P; Williams, J; Cardiovascular Health Study (CHS); - view fewer (2014) Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. PLoS One , 9 (6) , Article e94661. 10.1371/journal.pone.0094661.

Ferrari, R; Wang, Y; Vandrovcova, J; Guelfi, S; Witeolar, A; Karch, CM; Schork, AJ; ... Desikan, RS; + view all Ferrari, R; Wang, Y; Vandrovcova, J; Guelfi, S; Witeolar, A; Karch, CM; Schork, AJ; Fan, CC; Brewer, JB; Momeni, P; Schellenberg, GD; Dillon, WP; Sugrue, LP; Hess, CP; Yokoyama, JS; Bonham, LW; Rabinovici, GD; Miller, BL; Andreassen, OA; Dale, AM; Hardy, J; Desikan, RS; - view fewer (2017) Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases. Journal of Neurology, Neurosurgery and Psychiatry , 88 (2) pp. 152-164. 10.1136/jnnp-2016-314411.

Ford, L; Rudge, P; Robinson, K; Collinge, J; Gorham, M; Mead, S; (2019) The most problematic symptoms of prion disease - an analysis of carer experiences. International Psychogeriatrics , 31 (8) pp. 1181-1190. 10.1017/S1041610218001588.

Franko, E; Wehner, T; Joly, O; Lowe, J; Porter, MC; Kenny, J; Thompson, A; ... Mead, S; + view all Franko, E; Wehner, T; Joly, O; Lowe, J; Porter, MC; Kenny, J; Thompson, A; Rudge, P; Collinge, J; Mead, S; - view fewer (2016) Quantitative EEG parameters correlate with the progression of human prion diseases. Journal of Neurology, Neurosurgery & Psychiatry , 87 (10) pp. 1061-1067. 10.1136/jnnp-2016-313501.

Fratta, P; Poulter, M; Lashley, T; Rohrer, JD; Polke, JM; Beck, J; Ryan, N; ... Mead, S; + view all Fratta, P; Poulter, M; Lashley, T; Rohrer, JD; Polke, JM; Beck, J; Ryan, N; Hensman, D; Mizielinska, S; Waite, AJ; Lai, MC; Gendron, TF; Petrucelli, L; Fisher, EM; Revesz, T; Warren, JD; Collinge, J; Isaacs, AM; Mead, S; - view fewer (2013) Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia. Acta Neuropathologica , 126 (3) pp. 401-409. 10.1007/s00401-013-1147-0.

Freir, DB; Nicoll, AJ; Klyubin, I; Panico, S; Mc Donald, JM; Risse, E; Asante, EA; ... Collinge, J; + view all Freir, DB; Nicoll, AJ; Klyubin, I; Panico, S; Mc Donald, JM; Risse, E; Asante, EA; Farrow, MA; Sessions, RB; Saibil, HR; Clarke, AR; Rowan, MJ; Walsh, DM; Collinge, J; - view fewer (2011) Interaction between prion protein and toxic amyloid beta assemblies can be therapeutically targeted at multiple sites. Nature Communications , 2 , Article 336. 10.1038/ncomms1341.

Gao, Y; Wang, T; Yu, X; International FTD-Genomics Consortium (IFGC); Zhao, H; Zeng, P; (2020) Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis. Scientific Reports , 10 , Article 12184. 10.1038/s41598-020-68848-9.

Ge, YJ; Ou, YN; Deng, YT; Wu, BS; Yang, L; Zhang, YR; Chen, SD; ... Sorbi, S; + view all Ge, YJ; Ou, YN; Deng, YT; Wu, BS; Yang, L; Zhang, YR; Chen, SD; Huang, YY; Dong, Q; Tan, L; Yu, JT; Ferrari, R; Hernandez, DG; Nalls, MA; Rohrer, JD; Ramasamy, A; Kwok, JBJ; Dobson-Stone, C; Brooks, WS; Schofield, PR; Halliday, GM; Hodges, JR; Piguet, O; Bartley, L; Thompson, E; Haan, E; Hernández, I; Ruiz, A; Boada, M; Borroni, B; Padovani, A; Cruchaga, C; Cairns, NJ; Benussi, L; Binetti, G; Ghidoni, R; Forloni, G; Galimberti, D; Fenoglio, C; Serpente, M; Scarpini, E; Clarimón, J; Lleó, A; Blesa, R; Waldö, ML; Nilsson, K; Nilsson, C; Mackenzie, IRA; Hsiung, GYR; Mann, DMA; Grafman, J; Morris, CM; Attems, J; Griffiths, TD; McKeith, IG; Thomas, AJ; Pietrini, P; Huey, ED; Wassermann, EM; Baborie, A; Jaros, E; Tierney, MC; Pastor, P; Razquin, C; Ortega-Cubero, S; Alonso, E; Perneczky, R; Diehl-Schmid, J; Alexopoulos, P; Kurz, A; Rainero, I; Rubino, E; Pinessi, L; Rogaeva, E; St. George-Hyslop, P; Rossi, G; Tagliavini, F; Giaccone, G; Rowe, JB; Schlachetzki, JCM; Uphill, J; Collinge, J; Mead, S; Danek, A; Van Deerlin, VM; Grossman, M; Trojanowski, JQ; van der Zee, J; Deschamps, W; Van Langenhove, T; Cruts, M; Van Broeckhoven, C; Cappa, SF; Le Ber, I; Hannequin, D; Golfier, V; Vercelletto, M; Brice, A; Nacmias, B; Sorbi, S; - view fewer (2023) Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood. Biological Psychiatry , 93 (9) pp. 770-779. 10.1016/j.biopsych.2022.11.002.

Ghosh, U; Yau, W-M; Collinge, J; Tycko, R; (2021) Structural differences in amyloid-β fibrils from brains of non-demented elderly individuals and Alzheimer's disease patients. Proceedings of the National Academy of Sciences of the United States of America (PNAS) , 118 (45) , Article e2111863118. 10.1073/pnas.2111863118.

Grizenkova, J; Akhtar, S; Brandner, S; Collinge, J; Lloyd, SE; (2014) Microglial Cx3cr1 knockout reduces prion disease incubation time in mice. BMC Neurosci , 15 , Article 44. 10.1186/1471-2202-15-44.

Grizenkova, J; Akhtar, S; Collinge, J; Lloyd, SE; (2010) The Retinoic Acid Receptor Beta (Rarb) Region of Mmu14 Is Associated with Prion Disease Incubation Time in Mouse. PLOS ONE , 5 (12) , Article e15019. 10.1371/journal.pone.0015019.

Guerreiro, RJ; Beck, J; Gibbs, JR; Santana, I; Rossor, MN; Schott, JM; Nalls, MA; ... Hardy, J; + view all Guerreiro, RJ; Beck, J; Gibbs, JR; Santana, I; Rossor, MN; Schott, JM; Nalls, MA; Ribeiro, H; Santiago, B; Fox, NC; Oliveira, C; Collinge, J; Mead, S; Singleton, A; Hardy, J; - view fewer (2010) Genetic Variability in CLU and Its Association with Alzheimer's Disease. PLOS ONE , 5 (3) , Article e9510. 10.1371/journal.pone.0009510.

Hassan, A; Campbell, T; Darwent, L; Odd, H; Green, A; Collinge, J; Mead, S; (2021) Case report of homozygous E200D mutation of PRNP in apparently sporadic Creutzfeldt-Jakob disease. BMC Neurology , 21 , Article 248. 10.1186/s12883-021-02274-w.

Hosszu, LLP; Conners, R; Sangar, D; Batchelor, M; Sawyer, EB; Fisher, S; Cliff, MJ; ... Collinge, J; + view all Hosszu, LLP; Conners, R; Sangar, D; Batchelor, M; Sawyer, EB; Fisher, S; Cliff, MJ; Hounslow, AM; McAuley, K; Leo Brady, R; Jackson, GS; Bieschke, J; Waltho, JP; Collinge, J; - view fewer (2020) Structural effects of the highly protective V127 polymorphism on human prion protein. Communications Biology , 3 (1) , Article 402. 10.1038/s42003-020-01126-6.

Hu, NW; Nicoll, AJ; Zhang, D; Mably, AJ; O'Malley, T; Purro, SA; Terry, C; ... Rowan, MJ; + view all Hu, NW; Nicoll, AJ; Zhang, D; Mably, AJ; O'Malley, T; Purro, SA; Terry, C; Collinge, J; Walsh, DM; Rowan, MJ; - view fewer (2014) mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo. Nature Communications , 5 , Article 3374. 10.1038/ncomms4374.

Hyare, H; De Vita, E; Porter, M-C; Simpson, I; Ridgway, G; Lowe, J; Thompson, A; ... Thornton, JS; + view all Hyare, H; De Vita, E; Porter, M-C; Simpson, I; Ridgway, G; Lowe, J; Thompson, A; Carswell, C; Ourselin, S; Modat, M; Dos Santos Canas, L; Caine, D; Fox, Z; Rudge, P; Collinge, J; Mead, S; Thornton, JS; - view fewer (2020) Putaminal diffusion tensor imaging measures predict disease severity across human prion diseases. Brain Communications , 2 (1) , Article fcaa032. 10.1093/braincomms/fcaa032.

Jackson, Graham S; Linehan, Jacqueline; Brandner, Sebastian; Asante, Emmanuel A; Wadsworth, Jonathan DF; Collinge, John; (2022) Overexpression of mouse prion protein in transgenic mice causes a non-transmissible spongiform encephalopathy. Scientific Reports , 12 , Article 17198. 10.1038/s41598-022-21608-3.

Jesuthasan, Aaron; Sequeira, Danielle; Hyare, Harpreet; Odd, Hans; Rudge, Peter; Mok, Tze How; Nihat, Akin; ... Mead, Simon; + view all Jesuthasan, Aaron; Sequeira, Danielle; Hyare, Harpreet; Odd, Hans; Rudge, Peter; Mok, Tze How; Nihat, Akin; Collinge, John; Mead, Simon; - view fewer (2022) Assessing initial MRI reports for suspected CJD patients. Journal of Neurology 10.1007/s00415-022-11087-x. (In press).

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Katrak, S; Pauranik, A; Desai, S; Mead, S; Beck, J; Brandner, S; Collinge, J; (2019) Familial Creutzfeldt-Jakob disease in an Indian kindred. Annals of Indian Academy of Neurology , 22 (4) pp. 458-461. 10.4103/aian.AIAN_214_19.

Kenny, J; Woollacott, I; Koriath, C; Hosszu, L; Adamson, G; Rudge, P; Rossor, MN; ... Mead, S; + view all Kenny, J; Woollacott, I; Koriath, C; Hosszu, L; Adamson, G; Rudge, P; Rossor, MN; Collinge, J; Rohrer, JD; Mead, S; - view fewer (2017) A novel prion protein variant in a patient with semantic dementia. [Letter]. Journal of Neurology Neurosurgery and Psychiatry , 2017 (88) pp. 890-892. 10.1136/jnnp-2017-315577.

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L P Hosszu, Laszlo; Sangar, Daljit; Batchelor, Mark; Risse, Emmanuel; Hounslow, Andrea M; Collinge, John; Waltho, Jonathan P; L P Hosszu, Laszlo; Sangar, Daljit; Batchelor, Mark; Risse, Emmanuel; Hounslow, Andrea M; Collinge, John; Waltho, Jonathan P; Bieschke, Jan; - view fewer (2023) Loss of residues 119 – 136, including the first β-strand of human prion protein, generates an aggregation-competent partially “open” form. Journal of Molecular Biology , Article 168158. 10.1016/j.jmb.2023.168158. (In press).

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Lloyd, SE; Maytham, EG; Pota, H; Grizenkova, J; Molou, E; Uphill, J; Hummerich, H; ... Collinge, J; + view all Lloyd, SE; Maytham, EG; Pota, H; Grizenkova, J; Molou, E; Uphill, J; Hummerich, H; Whitfield, J; Alpers, MP; Mead, S; Collinge, J; - view fewer (2009) HECTD2 Is Associated with Susceptibility to Mouse and Human Prion Disease. PLOS GENET , 5 (2) , Article e1000383. 10.1371/journal.pgen.1000383.

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Sequeira, Danielle; Nihat, Akin; Mok, Tzehow; Coysh, Thomas; Rudge, Peter; Collinge, John; Mead, Simon; (2022) Prevalence and Treatments of Movement Disorders in Prion Diseases: A Longitudinal Cohort Study. Movement Disorders 10.1002/mds.29152. (In press).

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Thesis

Begum, R; (2013) Functional analysis of Hectd2: a prion disease modifier associated with incubation time. Doctoral thesis , UCL (University College London).

Reilly, Madeleine Louise; (2019) Development of an in vitro assay of prion-induced neurotoxicity. Doctoral thesis (Ph.D), UCL (University College London).

Thomas, David Mark Xavier; (2019) Investigating the biochemical signature and in vivo seeding activity of amyloid-β from distinct Alzheimer’s Disease subtypes. Doctoral thesis (Ph.D), UCL (University College London).

This list was generated on Tue Jan 27 13:37:17 2026 GMT.