Browse by UCL people
Group by: Type | Date
Number of items: 53.
Article
Andrews, KA;
Modat, M;
Macdonald, KE;
Yeatman, T;
Cardoso, MJ;
Leung, KK;
Barnes, J;
... Lifestyle Flagship Study of Ageing; + view all
(2013)
Atrophy rates in asymptomatic amyloidosis: implications for Alzheimer prevention trials.
PLoS One
, 8
(3)
, Article e58816. 10.1371/journal.pone.0058816.
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Barnes, Josephine;
Bartlett, Jonathan W;
Wolk, David A;
Van der Flier, Wiesje M;
Frost, Chris;
(2018)
Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease.
Journal of Alzheimer's Disease
, 64
(2)
pp. 631-642.
10.3233/JAD-170841.
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Barnes, J;
Carmichael, OT;
Leung, KK;
Schwarz, C;
Ridgway, GR;
Bartlett, JW;
Malone, IB;
... Alzheimer's Disease Neuroimaging Initiative, The; + view all
(2013)
Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls.
Neurobiology of Aging
, 34
(8)
1996 - 2002.
10.1016/j.neurobiolaging.2013.02.003.
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Barnes, J;
Dickerson, BC;
Frost, C;
Jiskoot, LC;
Wolk, D;
van der Flier, WM;
(2015)
Alzheimer's disease first symptoms are age dependent: Evidence from the NACC dataset.
Alzheimer's & Dementia
, 11
(11)
pp. 1349-1357.
10.1016/j.jalz.2014.12.007.
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Barnes, J;
Fox, NC;
(2014)
The search for early markers of AD: hippocampal atrophy and memory deficits.
Int Psychogeriatr
, 26
(7)
1065 - 1066.
10.1017/S1041610214000623.
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Biesbroek, J Matthijs;
Coenen, Mirthe;
DeCarli, Charles;
Fletcher, Evan M;
Maillard, Pauline M;
Alzheimer's Disease Neuroimaging Initiative;
Barkhof, Frederik;
... Biessels, Geert Jan; + view all
(2024)
Amyloid pathology and vascular risk are associated with distinct patterns of cerebral white matter hyperintensities: A multicenter study in 3132 memory clinic patients.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
10.1002/alz.13765.
(In press).
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Blenkinsop, A;
van der Flier, WM;
Wolk, D;
Lehmann, M;
Howard, R;
Frost, C;
Barnes, J;
(2020)
Non-memory cognitive symptom development in Alzheimer's disease.
European Journal of Neurology
, 27
(6)
pp. 995-1002.
10.1111/ene.14185.
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Bocchetta, M;
Gordon, E;
Manning, E;
Barnes, J;
Cash, DM;
Espak, M;
Thomas, DL;
... Rohrer, JD; + view all
(2015)
Detailed volumetric analysis of the hypothalamus in behavioral variant frontotemporal dementia.
Journal of Neurology
, 262
(12)
pp. 2635-2642.
10.1007/s00415-015-7885-2.
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Brown, Thomas M;
James, Sarah-Naomi;
Nicholas, Jennifer M;
Keuss, Sarah;
Keshavan, Ashvini;
Malone, Ian B;
Coath, William;
... Barnes, Josephine; + view all
(2025)
Association of Increase in White Matter Hyperintensity Volume With Rate of Hippocampal Atrophy in a Population-Based Study of Aging.
Neurology
, 105
(5)
, Article e213975. 10.1212/WNL.0000000000213975.
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Chan, D;
Anderson, V;
Pijnenburg, Y;
Whitwell, J;
Barnes, J;
Scahill, R;
Stevens, JM;
... Fox, NC; + view all
(2009)
The clinical profile of right temporal lobe atrophy.
Brain
, 132
(5)
pp. 1287-1298.
10.1093/brain/awp037.
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Coenen, Mirthe;
Biessels, Geert Jan;
DeCarli, Charles;
Fletcher, Evan F;
Maillard, Pauline M;
Alzheimer's Disease Neuroimaging Initiative;
Barkhof, Frederik;
... Kuijf, Hugo J; + view all
(2023)
Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts.
NeuroImage: Clinical
, 40
, Article 103547. 10.1016/j.nicl.2023.103547.
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Coenen, Mirthe;
Kuijf, Hugo J;
Huenges Wajer, Irene MC;
Duering, Marco;
Wolters, Frank J;
Fletcher, Evan F;
Maillard, Pauline M;
... Biesbroek, J Matthijs; + view all
(2022)
Strategic white matter hyperintensity locations for cognitive impairment: A multicenter lesion-symptom mapping study in 3525 memory clinic patients.
Alzheimer's & Dementia
10.1002/alz.12827.
(In press).
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Fiford, CM;
Sudre, CH;
Young, AL;
Macdougall, A;
Nicholas, J;
Manning, EN;
Malone, IB;
... Alzheimer’s Disease Neuroimaging Initiative, .; + view all
(2021)
Presumed small vessel disease, imaging and cognition markers in the Alzheimer's Disease Neuroimaging Initiative.
Brain Communications
, 3
(4)
, Article fcab226. 10.1093/braincomms/fcab226.
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Fiford, C;
Nicholas, J;
Biessels, GJ;
Lane, C;
Cardoso, MJ;
Barnes, J;
(2020)
High blood pressure predicts hippocampal atrophy rate in cognitively impaired elders.
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
, 12
(1)
, Article e12035. 10.1002/dad2.12035.
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Fiford, C;
Sudre, C;
Pemberton, H;
Walsh, P;
Manning, E;
Malone, I;
Nicholas, J;
... Barnes, J; + view all
(2020)
Automated white matter hyperintensity segmentation using Bayesian Model Selection: assessment and correlations with cognitive change.
NeuroInformatics
10.1007/s12021-019-09439-6.
(In press).
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Fiford, CM;
Manning, EN;
Bartlett, JW;
Cash, DM;
Malone, IB;
Ridgway, GR;
Lehmann, M;
... Alzheimer's Disease Neuroimaging Initiative; + view all
(2017)
White matter hyperintensities are associated with disproportionate progressive hippocampal atrophy.
Hippocampus
, 27
(3)
pp. 249-262.
10.1002/hipo.22690.
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Fiford, CM;
Ridgway, GR;
Cash, DM;
Modat, M;
Nicholas, J;
Manning, EN;
Malone, IB;
... Alzheimer's Disease Neuroimaging Initiative, .; + view all
(2018)
Patterns of progressive atrophy vary with age in Alzheimer's disease patients.
Neurobiology of Aging
, 63
pp. 22-32.
10.1016/j.neurobiolaging.2017.11.002.
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Harris, MJ;
Lane, CA;
Coath, W;
Malone, IB;
Cash, DM;
Barnes, J;
Barkhof, F;
(2022)
Familial British dementia: a clinical and multi-modal imaging case study.
Journal of Neurology
, 269
pp. 3926-3930.
10.1007/s00415-022-11036-8.
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Hoang Duc, AK;
Modat, M;
Leung, KK;
Cardoso, MJ;
Barnes, J;
Kadir, T;
Ourselin, S;
(2013)
Using manifold learning for atlas selection in multi-atlas segmentation.
PLoS One
, 8
(8)
, Article e70059. 10.1371/journal.pone.0070059.
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James, S-N;
Nicholas, JM;
Lane, CA;
Parker, TD;
Lu, K;
Keshavan, A;
Buchanan, SM;
... Fox, NC; + view all
(2021)
A population‐based study of head injury, cognitive function and pathological markers.
Annals of Clinical and Translational Neurology
10.1002/acn3.51331.
(In press).
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Jorge Cardoso, M;
Leung, K;
Modat, M;
Keihaninejad, S;
Cash, D;
Barnes, J;
Fox, NC;
... Alzheimer’s Disease Neuroimaging Initiative; + view all
(2013)
STEPS: Similarity and Truth Estimation for Propagated Segmentations and its application to hippocampal segmentation and brain parcelation.
Med Image Anal
, 17
(6)
671 - 684.
10.1016/j.media.2013.02.006.
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Kehoe, PG;
Turner, N;
Howden, B;
Jarutyt, L;
Clegg, SL;
Malone, IB;
Barnes, J;
... Ben-Shlomo, Y; + view all
(2021)
Losartan to slow the progression of mild-to-moderate Alzheimer's disease through angiotensin targeting: the RADAR RCT.
Efficacy and Mechanism Evaluation
, 8
(19)
pp. 1-72.
10.3310/eme08190.
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Kehoe, PG;
Turner, N;
Howden, B;
Jarutyte, L;
Clegg, SL;
Malone, IB;
Barnes, J;
... RADAR investigators, .; + view all
(2021)
Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial.
Lancet Neurology
, 20
(11)
pp. 895-906.
10.1016/S1474-4422(21)00263-5.
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Keuss, Sarah E;
Coath, William;
Cash, David M;
Barnes, Josephine;
Nicholas, Jennifer M;
Lane, Christopher A;
Parker, Thomas D;
... Schott, Jonathan M; + view all
(2024)
Rates of cortical thinning in Alzheimer's disease signature regions associate with vascular burden but not with β-amyloid status in cognitively normal adults at age 70.
Journal of Neurology, Neurosurgery, and Psychiatry
10.1136/jnnp-2023-332067.
(In press).
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Lane, CA;
Barnes, J;
Nicholas, JM;
Baker, JW;
Sudre, CH;
Cash, DM;
Parker, TD;
... Schott, JM; + view all
(2021)
Investigating the relationship between BMI across adulthood and late life brain pathologies.
Alzheimer's Research and Therapy
, 13
(1)
, Article 91. 10.1186/s13195-021-00830-7.
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Lane, CA;
Barnes, J;
Nicholas, JM;
Sudre, CH;
Cash, DM;
Malone, IB;
Parker, TD;
... Schott, JM; + view all
(2019)
Associations Between Vascular Risk Across Adulthood and Brain Pathology in Late Life: Evidence From a British Birth Cohort.
JAMA Neurology
, 77
(2)
pp. 175-183.
10.1001/jamaneurol.2019.3774.
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Lane, CA;
Barnes, J;
Nicholas, JM;
Sudre, CH;
Cash, DM;
Parker, TD;
Malone, IB;
... Schott, JM; + view all
(2019)
Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study.
Lancet Neurology
10.1016/S1474-4422(19)30228-5.
(In press).
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Lehmann, M;
Barnes, J;
Ridgway, GR;
Ryan, NS;
Warrington, EK;
Crutch, SJ;
Fox, NC;
(2012)
Global gray matter changes in posterior cortical atrophy: a serial imaging study.
Alzheimer's & Dementia
, 8
(6)
502 - 512.
10.1016/j.jalz.2011.09.225.
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Lehmann, M;
Rohrer, JD;
Clarkson, MJ;
Ridgway, GR;
Scahill, RI;
Modat, M;
Warren, JD;
... Fox, NC; + view all
(2010)
Reduced Cortical Thickness in the Posterior Cingulate Gyrus is Characteristic of Both Typical and Atypical Alzheimer's Disease.
J ALZHEIMERS DIS
, 20
(2)
587 - 598.
10.3233/JAD-2010-1401.
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Leung, KK;
Bartlett, JW;
Barnes, J;
Manning, EN;
Ourselin, S;
Fox, NC;
(2013)
Cerebral atrophy in mild cognitive impairment and Alzheimer disease: rates and acceleration.
Neurology
, 80
(7)
648 - 654.
10.1212/WNL.0b013e318281ccd3.
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Macdonald, KE;
Bartlett, JW;
Leung, KK;
Ourselin, S;
Barnes, J;
ADNI investigators;
(2013)
The value of hippocampal and temporal horn volumes and rates of change in predicting future conversion to AD.
Alzheimer Dis Assoc Disord
, 27
(2)
168 - 173.
10.1097/WAD.0b013e318260a79a.
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Malone, I;
Leung, KL;
Clegg, S;
Barnes, J;
Whitwell, JL;
Ashburner, J;
Fox, NC;
(2015)
Accurate automatic estimation of total intracranial volume: a nuisance variable with less nuisance.
Neuroimage
, 104
10.1016/j.neuroimage.2014.09.034.
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Manning, EN;
Barnes, J;
Cash, DM;
Bartlett, JW;
Leung, KK;
Ourselin, S;
Nick C. Fox1 for the Alzheimer's Disease NeuroImaging Initiative;
(2014)
APOE ε4 Is Associated with Disproportionate Progressive Hippocampal Atrophy in AD.
PLoS One
, 9
(5)
, Article e97608. 10.1371/journal.pone.0097608.
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Manning, EN;
Leung, KK;
Nicholas, JM;
Malone, IB;
Cardoso, MJ;
Schott, JM;
Fox, NC;
(2017)
A Comparison of Accelerated and Non-accelerated MRI Scans for Brain Volume and Boundary Shift Integral Measures of Volume Change: Evidence from the ADNI Dataset.
NEUROINFORMATICS
, 15
(2)
pp. 215-226.
10.1007/s12021-017-9326-0.
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Manning, EN;
Macdonald, KE;
Leung, KK;
Young, J;
Pepple, T;
Lehmann, M;
Zuluaga, MA;
... Barnes, J; + view all
(2015)
Differential hippocampal shapes in posterior cortical atrophy patients: A comparison with control and typical AD subjects.
Human Brain Mapping
, 36
(12)
pp. 5123-5136.
10.1002/hbm.22999.
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Modat, M.;
Ridgway, G.R.;
Taylor, Z.A.;
Lehmann, M.;
Barnes, J.;
Hawkes, D.J.;
Fox, N.C.;
(2010)
Fast free-form deformation using graphics processing units.
Computer Methods and Programs in Biomedicine
, 98
(3)
pp. 278-284.
10.1016/j.cmpb.2009.09.002.
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Murray-Smith, H;
Barker, S;
Barkhof, F;
Barnes, J;
Brown, TM;
Captur, G;
R.E.Cartlidge, M;
... Schott, JM; + view all
(2024)
Updating the study protocol: Insight 46 – a longitudinal neuroscience sub-study of the MRC National Survey of Health and Development – phases 2 and 3.
BMC Neurology
, 24
, Article 40. 10.1186/s12883-023-03465-3.
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Prosser, Lloyd;
MacDougall, Amy;
Sudre, Carole H;
Manning, Emily N;
Malone, Ian B;
Walsh, Phoebe;
Goodkin, Olivia;
... Barnes, Josephine; + view all
(2023)
Predicting Cognitive Decline in Nondemented Elders Using Baseline Metrics of AD Pathologies, Cerebrovascular Disease, and Neurodegeneration.
Neurology
, 100
(8)
e834-e845.
10.1212/WNL.0000000000201572.
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Prosser, Lloyd;
Sudre, Carole H;
Oxtoby, Neil P;
Young, Alexandra L;
Malone, Ian B;
Manning, Emily N;
Pemberton, Hugh;
... Barnes, Josephine; + view all
(2024)
Biomarker pathway heterogeneity of amyloid-positive individuals.
Alzheimer's & Dementia
, 20
(12)
pp. 8503-8515.
10.1002/alz.14287.
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Richards, Marcus;
James, Sarah N;
Lu, Kirsty;
Livingston, Gill;
Schott, Jonathan M;
Lane, Christopher A;
Barnes, Josephine;
... Davis, Daniel HJ; + view all
(2022)
Straight and Divergent Pathways to Cognitive State: Seven Decades of Follow-Up in the British 1946 Birth Cohort.
Journal of Alzheimer's Disease
, 89
(2)
pp. 659-667.
10.3233/JAD-220296.
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Sliz, Eeva;
Shin, Jean;
Ahmad, Shahzad;
Williams, Dylan M;
Frenzel, Stefan;
Gauß, Friederike;
Harris, Sarah E;
... NeuroCHARGE Working Group, .; + view all
(2022)
Circulating Metabolome and White Matter Hyperintensities in Females and Males.
Circulation
, 145
(14)
pp. 1040-1052.
10.1161/CIRCULATIONAHA.121.056892.
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Subramaniapillai, Sivaniya;
Schindler, Louise S;
Redmond, Paul;
Bastin, Mark E;
Wardlaw, Joanna M;
Hernandez, Maria Valdes;
Maniega, Susana Munoz;
... de Lange, Ann-Marie G; + view all
(2024)
Sex-Dependent Effects of Cardiometabolic Health and APOE4 on Brain Age: A Longitudinal Cohort Study.
Neurology
, 103
(6)
, Article e209744. 10.1212/WNL.0000000000209744.
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Sudre, Carole H;
Moriconi, Stefano;
Rehwald, Rafael;
Smith, Lorna;
Tillin, Therese;
Barnes, Josephine;
Atkinson, David;
... Cardoso, M Jorge; + view all
(2022)
Accelerated vascular aging: Ethnic differences in basilar artery length and diameter, and its association with cardiovascular risk factors and cerebral small vessel disease.
Frontiers in Cardiovascular Medicine
, 9
, Article 939680. 10.3389/fcvm.2022.939680.
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Sudre, C;
Cardoso, MJ;
Bouvy, W;
Biessels, G;
Barnes, J;
Ourselin, S;
(2015)
Bayesian model selection for pathological neuroimaging data applied to white matter lesion segmentation.
IEEE Transactions on Medical Imaging
, 34
(10)
pp. 2079-2102.
10.1109/TMI.2015.2419072.
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Sudre, CH;
Cardoso, MJ;
Frost, C;
Barnes, J;
Barkhof, F;
Fox, N;
Ourselin, S;
(2017)
APOE ε4 status is associated with white matter hyperintensities volume accumulation rate independent of AD diagnosis.
Neurobiology of Aging
, 53
pp. 67-75.
10.1016/j.neurobiolaging.2017.01.014.
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Tank, R;
Diaz, A;
Ashford, MT;
Miller, MJ;
Eichenbaum, J;
Aaronson, A;
Landavazo, B;
... Nosheny, RL; + view all
(2024)
Examining Demographic Factors, Psychosocial Wellbeing and Cardiovascular Health in Subjective Cognitive Decline in the Brain Health Registry Cohort.
Journal of Prevention of Alzheimer's Disease
10.14283/jpad.2024.39.
(In press).
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Wagen, AZ;
Coath, W;
Keshavan, A;
James, SN;
Parker, TD;
Lane, CA;
Buchanan, SM;
... Schott, JM; + view all
(2022)
Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study.
The Lancet Healthy Longevity
, 3
(9)
e607-e616.
10.1016/S2666-7568(22)00167-2.
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Walsh, P;
Sudre, CH;
Fiford, CM;
Ryan, NS;
Lashley, T;
Frost, C;
Barnes, J;
(2021)
The age-dependent associations of white matter hyperintensities and neurofilament light in early- and late-stage Alzheimer's disease.
Neurobiology of Aging
, 97
pp. 10-17.
10.1016/j.neurobiolaging.2020.09.008.
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Walsh, P;
Sudre, CH;
Fiford, CM;
Ryan, NS;
Lashley, T;
Frost, C;
Barnes, J;
(2020)
CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease.
Neurobiology of Aging
, 91
pp. 5-14.
10.1016/j.neurobiolaging.2020.03.008.
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Weaver, NA;
Zhao, L;
Biesbroek, JM;
Kuijf, HJ;
Aben, HP;
Bae, H-J;
Caballero, MÁA;
... Biessels, GJ; + view all
(2019)
The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: Design and multicenter pilot study.
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
, 11
pp. 310-326.
10.1016/j.dadm.2019.02.007.
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Book chapter
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Oliveira-Stahl, G;
Schroder, A;
Moggridge, J;
Salhab, HA;
Micallef, C;
Barnes, J;
Cardoso, MJ;
... Grech-Sollars, M; + view all
(2026)
Evaluation of Uncertainty-Aware Multi-software Ensembles for Hippocampal Segmentation.
In: Sudre, Carole H and Hoque, Mobarak I and Mehta, Raghav and Ouyang, Cheng and Qin, Chen and Rakic, Marianne and Wells, William M, (eds.)
Uncertainty for Safe Utilization of Machine Learning in Medical Imaging. UNSURE 2025.
(pp. 45-55).
Springer Nature Switzerland: Cham, Switzerland.
(In press).
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Proceedings paper
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Groothuis, I;
Sudre, CH;
Ingala, S;
Barnes, J;
Gispert, JD;
Sørensen, L;
Pai, A;
... Modat, M; + view all
(2021)
Lesion-wise evaluation for effective performance monitoring of small object segmentation.
In:
Proceedings SPIE 11596, Medical Imaging 2021: Image Processing.
SPIE
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Poster
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Ridgway, GR;
Barnes, J;
Pepple, T;
Fox, N;
(2011)
Estimation of total intracranial volume - a comparison of methods.
Presented at: AAICAD Alzheimer's Imaging Consortium, Paris, France.
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