Browse by UCL people
Group by: Type | Date
Number of items: 52.
Article
Andrews, KA;
Modat, M;
Macdonald, KE;
Yeatman, T;
Cardoso, MJ;
Leung, KK;
Barnes, J;
... Lifestyle Flagship Study of Ageing; + view all
(2013)
Atrophy rates in asymptomatic amyloidosis: implications for Alzheimer prevention trials.
PLoS One
, 8
(3)
, Article e58816. 10.1371/journal.pone.0058816.
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Barnes, Josephine;
Bartlett, Jonathan W;
Wolk, David A;
Van der Flier, Wiesje M;
Frost, Chris;
(2018)
Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease.
Journal of Alzheimer's Disease
, 64
(2)
pp. 631-642.
10.3233/JAD-170841.
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Barnes, J;
Carmichael, OT;
Leung, KK;
Schwarz, C;
Ridgway, GR;
Bartlett, JW;
Malone, IB;
... Alzheimer's Disease Neuroimaging Initiative, The; + view all
(2013)
Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls.
Neurobiology of Aging
, 34
(8)
1996 - 2002.
10.1016/j.neurobiolaging.2013.02.003.
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Barnes, J;
Dickerson, BC;
Frost, C;
Jiskoot, LC;
Wolk, D;
van der Flier, WM;
(2015)
Alzheimer's disease first symptoms are age dependent: Evidence from the NACC dataset.
Alzheimer's & Dementia
, 11
(11)
pp. 1349-1357.
10.1016/j.jalz.2014.12.007.
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Barnes, J;
Fox, NC;
(2014)
The search for early markers of AD: hippocampal atrophy and memory deficits.
Int Psychogeriatr
, 26
(7)
1065 - 1066.
10.1017/S1041610214000623.
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Biesbroek, J Matthijs;
Coenen, Mirthe;
DeCarli, Charles;
Fletcher, Evan M;
Maillard, Pauline M;
Alzheimer's Disease Neuroimaging Initiative;
Barkhof, Frederik;
... Biessels, Geert Jan; + view all
(2024)
Amyloid pathology and vascular risk are associated with distinct patterns of cerebral white matter hyperintensities: A multicenter study in 3132 memory clinic patients.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
10.1002/alz.13765.
(In press).
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Blenkinsop, A;
van der Flier, WM;
Wolk, D;
Lehmann, M;
Howard, R;
Frost, C;
Barnes, J;
(2020)
Non-memory cognitive symptom development in Alzheimer's disease.
European Journal of Neurology
, 27
(6)
pp. 995-1002.
10.1111/ene.14185.
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Bocchetta, M;
Gordon, E;
Manning, E;
Barnes, J;
Cash, DM;
Espak, M;
Thomas, DL;
... Rohrer, JD; + view all
(2015)
Detailed volumetric analysis of the hypothalamus in behavioral variant frontotemporal dementia.
Journal of Neurology
, 262
(12)
pp. 2635-2642.
10.1007/s00415-015-7885-2.
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Brown, Thomas M;
James, Sarah-Naomi;
Nicholas, Jennifer M;
Keuss, Sarah;
Keshavan, Ashvini;
Malone, Ian B;
Coath, William;
... Barnes, Josephine; + view all
(2025)
Association of Increase in White Matter Hyperintensity Volume With Rate of Hippocampal Atrophy in a Population-Based Study of Aging.
Neurology
, 105
(5)
, Article e213975. 10.1212/WNL.0000000000213975.
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Chan, D;
Anderson, V;
Pijnenburg, Y;
Whitwell, J;
Barnes, J;
Scahill, R;
Stevens, JM;
... Fox, NC; + view all
(2009)
The clinical profile of right temporal lobe atrophy.
Brain
, 132
(5)
pp. 1287-1298.
10.1093/brain/awp037.
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Coenen, Mirthe;
Biessels, Geert Jan;
DeCarli, Charles;
Fletcher, Evan F;
Maillard, Pauline M;
Alzheimer's Disease Neuroimaging Initiative;
Barkhof, Frederik;
... Kuijf, Hugo J; + view all
(2023)
Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts.
NeuroImage: Clinical
, 40
, Article 103547. 10.1016/j.nicl.2023.103547.
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Coenen, Mirthe;
Kuijf, Hugo J;
Huenges Wajer, Irene MC;
Duering, Marco;
Wolters, Frank J;
Fletcher, Evan F;
Maillard, Pauline M;
... Biesbroek, J Matthijs; + view all
(2022)
Strategic white matter hyperintensity locations for cognitive impairment: A multicenter lesion-symptom mapping study in 3525 memory clinic patients.
Alzheimer's & Dementia
10.1002/alz.12827.
(In press).
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Fiford, CM;
Sudre, CH;
Young, AL;
Macdougall, A;
Nicholas, J;
Manning, EN;
Malone, IB;
... Alzheimer’s Disease Neuroimaging Initiative, .; + view all
(2021)
Presumed small vessel disease, imaging and cognition markers in the Alzheimer's Disease Neuroimaging Initiative.
Brain Communications
, 3
(4)
, Article fcab226. 10.1093/braincomms/fcab226.
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Fiford, C;
Nicholas, J;
Biessels, GJ;
Lane, C;
Cardoso, MJ;
Barnes, J;
(2020)
High blood pressure predicts hippocampal atrophy rate in cognitively impaired elders.
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
, 12
(1)
, Article e12035. 10.1002/dad2.12035.
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Fiford, C;
Sudre, C;
Pemberton, H;
Walsh, P;
Manning, E;
Malone, I;
Nicholas, J;
... Barnes, J; + view all
(2020)
Automated white matter hyperintensity segmentation using Bayesian Model Selection: assessment and correlations with cognitive change.
NeuroInformatics
10.1007/s12021-019-09439-6.
(In press).
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Fiford, CM;
Manning, EN;
Bartlett, JW;
Cash, DM;
Malone, IB;
Ridgway, GR;
Lehmann, M;
... Alzheimer's Disease Neuroimaging Initiative; + view all
(2017)
White matter hyperintensities are associated with disproportionate progressive hippocampal atrophy.
Hippocampus
, 27
(3)
pp. 249-262.
10.1002/hipo.22690.
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Fiford, CM;
Ridgway, GR;
Cash, DM;
Modat, M;
Nicholas, J;
Manning, EN;
Malone, IB;
... Alzheimer's Disease Neuroimaging Initiative, .; + view all
(2018)
Patterns of progressive atrophy vary with age in Alzheimer's disease patients.
Neurobiology of Aging
, 63
pp. 22-32.
10.1016/j.neurobiolaging.2017.11.002.
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Harris, MJ;
Lane, CA;
Coath, W;
Malone, IB;
Cash, DM;
Barnes, J;
Barkhof, F;
(2022)
Familial British dementia: a clinical and multi-modal imaging case study.
Journal of Neurology
, 269
pp. 3926-3930.
10.1007/s00415-022-11036-8.
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Hoang Duc, AK;
Modat, M;
Leung, KK;
Cardoso, MJ;
Barnes, J;
Kadir, T;
Ourselin, S;
(2013)
Using manifold learning for atlas selection in multi-atlas segmentation.
PLoS One
, 8
(8)
, Article e70059. 10.1371/journal.pone.0070059.
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James, S-N;
Nicholas, JM;
Lane, CA;
Parker, TD;
Lu, K;
Keshavan, A;
Buchanan, SM;
... Fox, NC; + view all
(2021)
A population‐based study of head injury, cognitive function and pathological markers.
Annals of Clinical and Translational Neurology
10.1002/acn3.51331.
(In press).
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Jorge Cardoso, M;
Leung, K;
Modat, M;
Keihaninejad, S;
Cash, D;
Barnes, J;
Fox, NC;
... Alzheimer’s Disease Neuroimaging Initiative; + view all
(2013)
STEPS: Similarity and Truth Estimation for Propagated Segmentations and its application to hippocampal segmentation and brain parcelation.
Med Image Anal
, 17
(6)
671 - 684.
10.1016/j.media.2013.02.006.
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Kehoe, PG;
Turner, N;
Howden, B;
Jarutyt, L;
Clegg, SL;
Malone, IB;
Barnes, J;
... Ben-Shlomo, Y; + view all
(2021)
Losartan to slow the progression of mild-to-moderate Alzheimer's disease through angiotensin targeting: the RADAR RCT.
Efficacy and Mechanism Evaluation
, 8
(19)
pp. 1-72.
10.3310/eme08190.
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Kehoe, PG;
Turner, N;
Howden, B;
Jarutyte, L;
Clegg, SL;
Malone, IB;
Barnes, J;
... RADAR investigators, .; + view all
(2021)
Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial.
Lancet Neurology
, 20
(11)
pp. 895-906.
10.1016/S1474-4422(21)00263-5.
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Keuss, Sarah E;
Coath, William;
Cash, David M;
Barnes, Josephine;
Nicholas, Jennifer M;
Lane, Christopher A;
Parker, Thomas D;
... Schott, Jonathan M; + view all
(2024)
Rates of cortical thinning in Alzheimer's disease signature regions associate with vascular burden but not with β-amyloid status in cognitively normal adults at age 70.
Journal of Neurology, Neurosurgery, and Psychiatry
10.1136/jnnp-2023-332067.
(In press).
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Lane, CA;
Barnes, J;
Nicholas, JM;
Baker, JW;
Sudre, CH;
Cash, DM;
Parker, TD;
... Schott, JM; + view all
(2021)
Investigating the relationship between BMI across adulthood and late life brain pathologies.
Alzheimer's Research and Therapy
, 13
(1)
, Article 91. 10.1186/s13195-021-00830-7.
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Lane, CA;
Barnes, J;
Nicholas, JM;
Sudre, CH;
Cash, DM;
Malone, IB;
Parker, TD;
... Schott, JM; + view all
(2019)
Associations Between Vascular Risk Across Adulthood and Brain Pathology in Late Life: Evidence From a British Birth Cohort.
JAMA Neurology
, 77
(2)
pp. 175-183.
10.1001/jamaneurol.2019.3774.
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Lane, CA;
Barnes, J;
Nicholas, JM;
Sudre, CH;
Cash, DM;
Parker, TD;
Malone, IB;
... Schott, JM; + view all
(2019)
Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study.
Lancet Neurology
10.1016/S1474-4422(19)30228-5.
(In press).
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Lehmann, M;
Barnes, J;
Ridgway, GR;
Ryan, NS;
Warrington, EK;
Crutch, SJ;
Fox, NC;
(2012)
Global gray matter changes in posterior cortical atrophy: a serial imaging study.
Alzheimer's & Dementia
, 8
(6)
502 - 512.
10.1016/j.jalz.2011.09.225.
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Lehmann, M;
Rohrer, JD;
Clarkson, MJ;
Ridgway, GR;
Scahill, RI;
Modat, M;
Warren, JD;
... Fox, NC; + view all
(2010)
Reduced Cortical Thickness in the Posterior Cingulate Gyrus is Characteristic of Both Typical and Atypical Alzheimer's Disease.
J ALZHEIMERS DIS
, 20
(2)
587 - 598.
10.3233/JAD-2010-1401.
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Leung, KK;
Bartlett, JW;
Barnes, J;
Manning, EN;
Ourselin, S;
Fox, NC;
(2013)
Cerebral atrophy in mild cognitive impairment and Alzheimer disease: rates and acceleration.
Neurology
, 80
(7)
648 - 654.
10.1212/WNL.0b013e318281ccd3.
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Macdonald, KE;
Bartlett, JW;
Leung, KK;
Ourselin, S;
Barnes, J;
ADNI investigators;
(2013)
The value of hippocampal and temporal horn volumes and rates of change in predicting future conversion to AD.
Alzheimer Dis Assoc Disord
, 27
(2)
168 - 173.
10.1097/WAD.0b013e318260a79a.
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Malone, I;
Leung, KL;
Clegg, S;
Barnes, J;
Whitwell, JL;
Ashburner, J;
Fox, NC;
(2015)
Accurate automatic estimation of total intracranial volume: a nuisance variable with less nuisance.
Neuroimage
, 104
10.1016/j.neuroimage.2014.09.034.
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Manning, EN;
Barnes, J;
Cash, DM;
Bartlett, JW;
Leung, KK;
Ourselin, S;
Nick C. Fox1 for the Alzheimer's Disease NeuroImaging Initiative;
(2014)
APOE ε4 Is Associated with Disproportionate Progressive Hippocampal Atrophy in AD.
PLoS One
, 9
(5)
, Article e97608. 10.1371/journal.pone.0097608.
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Manning, EN;
Leung, KK;
Nicholas, JM;
Malone, IB;
Cardoso, MJ;
Schott, JM;
Fox, NC;
(2017)
A Comparison of Accelerated and Non-accelerated MRI Scans for Brain Volume and Boundary Shift Integral Measures of Volume Change: Evidence from the ADNI Dataset.
NEUROINFORMATICS
, 15
(2)
pp. 215-226.
10.1007/s12021-017-9326-0.
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Manning, EN;
Macdonald, KE;
Leung, KK;
Young, J;
Pepple, T;
Lehmann, M;
Zuluaga, MA;
... Barnes, J; + view all
(2015)
Differential hippocampal shapes in posterior cortical atrophy patients: A comparison with control and typical AD subjects.
Human Brain Mapping
, 36
(12)
pp. 5123-5136.
10.1002/hbm.22999.
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Modat, M.;
Ridgway, G.R.;
Taylor, Z.A.;
Lehmann, M.;
Barnes, J.;
Hawkes, D.J.;
Fox, N.C.;
(2010)
Fast free-form deformation using graphics processing units.
Computer Methods and Programs in Biomedicine
, 98
(3)
pp. 278-284.
10.1016/j.cmpb.2009.09.002.
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Murray-Smith, H;
Barker, S;
Barkhof, F;
Barnes, J;
Brown, TM;
Captur, G;
R.E.Cartlidge, M;
... Schott, JM; + view all
(2024)
Updating the study protocol: Insight 46 – a longitudinal neuroscience sub-study of the MRC National Survey of Health and Development – phases 2 and 3.
BMC Neurology
, 24
, Article 40. 10.1186/s12883-023-03465-3.
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Prosser, Lloyd;
MacDougall, Amy;
Sudre, Carole H;
Manning, Emily N;
Malone, Ian B;
Walsh, Phoebe;
Goodkin, Olivia;
... Barnes, Josephine; + view all
(2023)
Predicting Cognitive Decline in Nondemented Elders Using Baseline Metrics of AD Pathologies, Cerebrovascular Disease, and Neurodegeneration.
Neurology
, 100
(8)
e834-e845.
10.1212/WNL.0000000000201572.
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Prosser, Lloyd;
Sudre, Carole H;
Oxtoby, Neil P;
Young, Alexandra L;
Malone, Ian B;
Manning, Emily N;
Pemberton, Hugh;
... Barnes, Josephine; + view all
(2024)
Biomarker pathway heterogeneity of amyloid-positive individuals.
Alzheimer's & Dementia
, 20
(12)
pp. 8503-8515.
10.1002/alz.14287.
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Richards, Marcus;
James, Sarah N;
Lu, Kirsty;
Livingston, Gill;
Schott, Jonathan M;
Lane, Christopher A;
Barnes, Josephine;
... Davis, Daniel HJ; + view all
(2022)
Straight and Divergent Pathways to Cognitive State: Seven Decades of Follow-Up in the British 1946 Birth Cohort.
Journal of Alzheimer's Disease
, 89
(2)
pp. 659-667.
10.3233/JAD-220296.
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Sliz, Eeva;
Shin, Jean;
Ahmad, Shahzad;
Williams, Dylan M;
Frenzel, Stefan;
Gauß, Friederike;
Harris, Sarah E;
... NeuroCHARGE Working Group, .; + view all
(2022)
Circulating Metabolome and White Matter Hyperintensities in Females and Males.
Circulation
, 145
(14)
pp. 1040-1052.
10.1161/CIRCULATIONAHA.121.056892.
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Subramaniapillai, Sivaniya;
Schindler, Louise S;
Redmond, Paul;
Bastin, Mark E;
Wardlaw, Joanna M;
Hernandez, Maria Valdes;
Maniega, Susana Munoz;
... de Lange, Ann-Marie G; + view all
(2024)
Sex-Dependent Effects of Cardiometabolic Health and APOE4 on Brain Age: A Longitudinal Cohort Study.
Neurology
, 103
(6)
, Article e209744. 10.1212/WNL.0000000000209744.
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Sudre, Carole H;
Moriconi, Stefano;
Rehwald, Rafael;
Smith, Lorna;
Tillin, Therese;
Barnes, Josephine;
Atkinson, David;
... Cardoso, M Jorge; + view all
(2022)
Accelerated vascular aging: Ethnic differences in basilar artery length and diameter, and its association with cardiovascular risk factors and cerebral small vessel disease.
Frontiers in Cardiovascular Medicine
, 9
, Article 939680. 10.3389/fcvm.2022.939680.
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Sudre, C;
Cardoso, MJ;
Bouvy, W;
Biessels, G;
Barnes, J;
Ourselin, S;
(2015)
Bayesian model selection for pathological neuroimaging data applied to white matter lesion segmentation.
IEEE Transactions on Medical Imaging
, 34
(10)
pp. 2079-2102.
10.1109/TMI.2015.2419072.
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Sudre, CH;
Cardoso, MJ;
Frost, C;
Barnes, J;
Barkhof, F;
Fox, N;
Ourselin, S;
(2017)
APOE ε4 status is associated with white matter hyperintensities volume accumulation rate independent of AD diagnosis.
Neurobiology of Aging
, 53
pp. 67-75.
10.1016/j.neurobiolaging.2017.01.014.
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Tank, R;
Diaz, A;
Ashford, MT;
Miller, MJ;
Eichenbaum, J;
Aaronson, A;
Landavazo, B;
... Nosheny, RL; + view all
(2024)
Examining Demographic Factors, Psychosocial Wellbeing and Cardiovascular Health in Subjective Cognitive Decline in the Brain Health Registry Cohort.
Journal of Prevention of Alzheimer's Disease
10.14283/jpad.2024.39.
(In press).
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Wagen, AZ;
Coath, W;
Keshavan, A;
James, SN;
Parker, TD;
Lane, CA;
Buchanan, SM;
... Schott, JM; + view all
(2022)
Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study.
The Lancet Healthy Longevity
, 3
(9)
e607-e616.
10.1016/S2666-7568(22)00167-2.
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Walsh, P;
Sudre, CH;
Fiford, CM;
Ryan, NS;
Lashley, T;
Frost, C;
Barnes, J;
(2021)
The age-dependent associations of white matter hyperintensities and neurofilament light in early- and late-stage Alzheimer's disease.
Neurobiology of Aging
, 97
pp. 10-17.
10.1016/j.neurobiolaging.2020.09.008.
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Walsh, P;
Sudre, CH;
Fiford, CM;
Ryan, NS;
Lashley, T;
Frost, C;
Barnes, J;
(2020)
CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease.
Neurobiology of Aging
, 91
pp. 5-14.
10.1016/j.neurobiolaging.2020.03.008.
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Weaver, NA;
Zhao, L;
Biesbroek, JM;
Kuijf, HJ;
Aben, HP;
Bae, H-J;
Caballero, MÁA;
... Biessels, GJ; + view all
(2019)
The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: Design and multicenter pilot study.
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
, 11
pp. 310-326.
10.1016/j.dadm.2019.02.007.
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Proceedings paper
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Groothuis, I;
Sudre, CH;
Ingala, S;
Barnes, J;
Gispert, JD;
Sørensen, L;
Pai, A;
... Modat, M; + view all
(2021)
Lesion-wise evaluation for effective performance monitoring of small object segmentation.
In:
Proceedings SPIE 11596, Medical Imaging 2021: Image Processing.
SPIE
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Poster
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Ridgway, GR;
Barnes, J;
Pepple, T;
Fox, N;
(2011)
Estimation of total intracranial volume - a comparison of methods.
Presented at: AAICAD Alzheimer's Imaging Consortium, Paris, France.
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