Browse by UCL people
Group by: Type | Date
Number of items: 60.
2025
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Hoose, Alex;
Garcia-Ruiz, Javier;
Blake, Corrin;
Lally, Ciara CM;
Briones, Andrea;
Hoogenboom, Bart W;
Lorenz, Christian D;
(2025)
Multimodal Membrane Poration by Thanatin.
Langmuir
, 41
(6)
pp. 3757-3767.
10.1021/acs.langmuir.4c03439.
|
2024
Benn, Georgina;
Borrelli, Carolina;
Prakaash, Dheeraj;
Johnson, Alex NT;
Fideli, Vincent A;
Starr, Tahj;
Fitzmaurice, Dylan;
... Silhavy, Thomas J; + view all
(2024)
OmpA controls order in the outer membrane and shares the mechanical load.
Proceedings of the National Academy of Sciences (PNAS)
, 121
(50)
, Article e2416426121. 10.1073/pnas.2416426121.
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2023
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Benn, Georgina;
Silhavy, Thomas J;
Kleanthous, Colin;
Hoogenboom, Bart W;
(2023)
Antibiotics and hexagonal order in the bacterial outer membrane.
Nature Communications
, 14
(1)
, Article 4772. 10.1038/s41467-023-40275-0.
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2022
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Beton, Joseph George;
Monistrol, Jim;
Wentink, Anne;
Johnston, Erin C;
Roberts, Anthony John;
Bukau, Bernd Gerhard;
Hoogenboom, Bart W;
(2022)
Cooperative amyloid fibre binding and disassembly by the Hsp70 disaggregase.
The EMBO Journal
, 2022
, Article e110410. 10.15252/embj.2021110410.
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Davis, LK;
Ford, IJ;
Hoogenboom, BW;
(2022)
Crowding-induced phase separation of nuclear transport receptors in FG nucleoporin assemblies.
eLife
, 11
, Article e72627. 10.7554/eLife.72627.
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Hammond, Katharine;
Moffat, Jonathan;
Mulcahy, Chris;
Hoogenboom, Bart W;
Ryadnov, Maxim G;
(2022)
In situ nanoscale imaging reveals self-concentrating nanomolar antimicrobial pores.
Nanoscale
, 14
(24)
pp. 8586-8593.
10.1039/d2nr00434h.
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Webby, Melissa N;
Oluwole, Abraham O;
Pedebos, Conrado;
Inns, Patrick G;
Olerinyova, Anna;
Prakaash, Dheeraj;
Housden, Nicholas G;
... Kleanthous, Colin; + view all
(2022)
Lipids mediate supramolecular outer membrane protein assembly in bacteria.
Science Advances
, 8
(44)
, Article eadc9566. 10.1126/sciadv.adc9566.
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2021
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Bell, NAW;
Haynes, PJ;
Brunner, K;
de Oliveira, TM;
Flocco, MM;
Hoogenboom, BW;
Molloy, JE;
(2021)
Single-molecule measurements reveal that PARP1 condenses DNA by loop stabilization.
Science Advances
, 7
(33)
, Article eabf3641. 10.1126/sciadv.abf3641.
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Benn, G;
Mikheyeva, IV;
Inns, PG;
Forster, JC;
Ojkic, N;
Bortolini, C;
Ryadnov, MG;
... Hoogenboom, BW; + view all
(2021)
Phase separation in the outer membrane of Escherichia coli.
Proceedings of the National Academy of Sciences
, 118
(44)
, Article e2112237118. 10.1073/pnas.2112237118.
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Beton, JG;
Moorehead, R;
Helfmann, L;
Gray, R;
Hoogenboom, BW;
Praveen Joseph, A;
Topf, M;
(2021)
TopoStats - a program for automated tracing of biomolecules from AFM images.
Methods
, 193
pp. 68-79.
10.1016/j.ymeth.2021.01.008.
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Davis, LK;
Šarić, A;
Hoogenboom, BW;
Zilman, A;
(2021)
Physical modelling of multivalent interactions in the nuclear pore complex.
Biophysical Journal
, 120
(9)
pp. 1565-1577.
10.1016/j.bpj.2021.01.039.
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Hammond, K;
Cipcigan, F;
Al Nahas, K;
Losasso, V;
Lewis, H;
Cama, J;
Martelli, F;
... Ryadnov, MG; + view all
(2021)
Switching Cytolytic Nanopores into Antimicrobial Fractal Ruptures by a Single Side Chain Mutation.
ACS Nano
, 15
(6)
pp. 9679-9689.
10.1021/acsnano.1c00218.
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Hammond, K;
Hoogenboom, BW;
Ryadnov, MG;
(2021)
Membrane disrupting peptides: Mechanistic elucidation of antimicrobial activity.
In: Ryadnov, M and Hudecz, F, (eds.)
Amino Acids, Peptides and Proteins: Volume 44.
(pp. 115-139).
Royal Society of Chemistry: London, UK.
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Hammond, K;
Benn, G;
Bennett, I;
Parsons, ES;
Ryadnov, MG;
Hoogenboom, BW;
Pyne, ALB;
(2021)
Imaging the Effects of Peptide Materials on Phospholipid Membranes by Atomic Force Microscopy.
Methods in Molecular Biology
, 2208
pp. 225-235.
10.1007/978-1-0716-0928-6_15.
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Hammond, K;
Ryadnov, MG;
Hoogenboom, BW;
(2021)
Atomic force microscopy to elucidate how peptides disrupt membranes.
Biochimica et Biophysica Acta (BBA) - Biomembranes
, 1863
(1)
, Article 183447. 10.1016/j.bbamem.2020.183447.
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Hoogenboom, BW;
(2021)
Stretching the resolution limit of atomic force microscopy.
Nature Structural & Molecular Biology
, 28
pp. 629-630.
10.1038/s41594-021-00638-x.
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Hoogenboom, BW;
Hough, LE;
Lemke, EA;
Lim, RYH;
Onck, PR;
Zilman, A;
(2021)
Physics of the nuclear pore complex: Theory, modeling and experiment.
Physics Reports
, 921
pp. 1-53.
10.1016/j.physrep.2021.03.003.
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Pyne, ALB;
Noy, A;
Main, KHS;
Velasco-Berrelleza, V;
Piperakis, MM;
Mitchenall, LA;
Cugliandolo, FM;
... Harris, SA; + view all
(2021)
Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides.
Nature Communications
, 12
(1)
, Article 1053. 10.1038/s41467-021-21243-y.
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2020
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Davis, LK;
Ford, IJ;
Šarić, A;
Hoogenboom, BW;
(2020)
Intrinsically disordered nuclear pore proteins show ideal-polymer morphologies and dynamics.
Physical Review E
, 101
(2)
, Article 022420. 10.1103/physreve.101.022420.
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Doorduijn, DJ;
Bardoel, BW;
Heesterbeek, DAC;
Ruyken, M;
Benn, G;
Parsons, ES;
Hoogenboom, BW;
(2020)
Bacterial killing by complement requires direct anchoring of membrane attack complex precursor C5b-7.
PLOS Pathogens
, 16
(6)
, Article e1008606. 10.1371/journal.ppat.1008606.
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Hammond, K;
Lewis, H;
Halliwell, S;
Desriac, F;
Nardone, B;
Ravi, J;
Hoogenboom, BW;
... Ryadnov, MG; + view all
(2020)
Flowering poration – a synergistic multi-mode antibacterial mechanism by a bacteriocin fold.
iScience
, Article 101423. 10.1016/j.isci.2020.101423.
(In press).
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Hodel, AW;
Rudd-Schmidt, J;
Trapani, JA;
Voskoboinik, I;
Hoogenboom, B;
(2020)
Lipid specificity of the immune effector perforin.
Faraday Discussions
10.1039/d0fd00043d.
(In press).
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Kepiro, IE;
Marzuoli, I;
Hammond, K;
Ba, X;
Lewis, H;
Shaw, M;
Gunnoo, SB;
... Ryadnov, MG; + view all
(2020)
Engineering Chirally Blind Protein Pseudocapsids into Antibacterial Persisters.
ACS Nano
, 14
(2)
pp. 1609-1622.
10.1021/acsnano.9b06814.
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Shah, NR;
Voisin, TB;
Parsons, ES;
Boyd, CM;
Hoogenboom, BW;
Bubeck, D;
(2020)
Structural basis for tuning activity and membrane specificity of bacterial cytolysins.
Nature Communications
, 11
, Article 5818. 10.1038/s41467-020-19482-6.
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Suthar, J;
Parsons, ES;
Hoogenboom, BW;
Williams, GR;
Guldin, S;
(2020)
Acoustic Immunosensing of Exosomes Using a Quartz Crystal Microbalance with Dissipation Monitoring.
Analytical Chemistry
, 92
(5)
pp. 4082-4093.
10.1021/acs.analchem.9b05736.
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2019
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Akpinar, B;
Haynes, PJ;
Bell, NAW;
Brunner, K;
Pyne, ALB;
Hoogenboom, BW;
(2019)
PEGylated surfaces for the study of DNA-protein interactions by atomic force microscopy.
Nanoscale
10.1039/c9nr07104k.
(In press).
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Benn, G;
Pyne, ALB;
Ryadnov, MG;
Hoogenboom, BW;
(2019)
Imaging live bacteria at the nanoscale: comparison of immobilisation strategies.
Analyst
10.1039/c9an01185d.
(In press).
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Hammond, K;
Lewis, H;
Faruqui, N;
Russell, C;
Hoogenboom, BW;
Ryadnov, MG;
(2019)
Helminth Defense Molecules as Design Templates for Membrane Active Antibiotics.
ACS Infectious Diseases
10.1021/acsinfecdis.9b00157.
(In press).
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Heesterbeek, DA;
Bardoel, BW;
Parsons, ES;
Bennett, I;
Ruyken, M;
Doorduijn, DJ;
Gorham, RD;
... Rooijakkers, SH; + view all
(2019)
Bacterial killing by complement requires membrane attack complex formation via surface-bound C5 convertases.
EMBO Journal
, Article e99852. 10.15252/embj.201899852.
(In press).
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Pang, SS;
Bayly-Jones, C;
Radjainia, M;
Spicer, BA;
Law, RHP;
Hodel, AW;
Parsons, ES;
... Whisstock, JC; + view all
(2019)
The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nature Communications
, 10
, Article 4288. 10.1038/s41467-019-12279-2.
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Parsons, ES;
Stanley, GJ;
Pyne, ALB;
Hodel, AW;
Nievergelt, AP;
Menny, A;
Yon, AR;
... Hoogenboom, BW; + view all
(2019)
Single-molecule kinetics of pore assembly by the membrane attack complex.
Nature Communications
, 10
, Article 2066. 10.1038/s41467-019-10058-7.
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Rudd-Schmidt, JA;
Hodel, AW;
Noori, T;
Lopez, JA;
Cho, H-J;
Verschoor, S;
Ciccone, A;
... Voskoboinik, I; + view all
(2019)
Lipid order and charge protect killer T cells from accidental death.
Nature Communications
, 10
(1)
, Article 5396. 10.1038/s41467-019-13385-x.
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Stanley, GJ;
Akpinar, B;
Shen, Q;
Fisher, PDE;
Lusk, CP;
Lin, C;
Hoogenboom, BW;
(2019)
Quantification of Biomolecular Dynamics Inside Real and Synthetic Nuclear Pore Complexes Using Time-Resolved Atomic Force Microscopy.
ACS Nano
10.1021/acsnano.9b02424.
(In press).
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2018
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Fisher, PDE;
Shen, Q;
Akpinar, B;
Davis, LK;
Chung, KKH;
Baddeley, D;
Šarić, A;
... Lusk, CP; + view all
(2018)
A Programmable DNA Origami Platform for Organizing Intrinsically Disordered Nucleoporins within Nanopore Confinement.
ACS Nano
, 12
(2)
pp. 1508-1518.
10.1021/acsnano.7b08044.
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Hoogenboom, BW;
Leake, MC;
(2018)
The case for biophysics super-groups in physics departments.
Physical Biology
, 15
(6)
, Article 060201. 10.1088/1478-3975/aaca0a.
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Pfeil, M-P;
Pyne, ALB;
Losasso, V;
Ravi, J;
Lamarre, B;
Faruqui, N;
Alkassem, H;
... Ryadnov, MG; + view all
(2018)
Tuneable poration: host defense peptides as sequence probes for antimicrobial mechanisms.
Scientific Reports
, 8
, Article 14926. 10.1038/s41598-018-33289-y.
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Stanley, GJ;
Fassati, A;
Hoogenboom, BW;
(2018)
Atomic force microscopy reveals structural variability amongst nuclear pore complexes.
Life Science Alliance
, 1
(4)
, Article e201800142. 10.26508/lsa.201800142.
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2017
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De Santis, E;
Alkassem, H;
Lamarre, B;
Faruqui, N;
Bella, A;
Noble, JE;
Micale, N;
... Ryadnov, MG; + view all
(2017)
Antimicrobial peptide capsids of de novo design.
Nature Communications
, 8
(1)
, Article 2263. 10.1038/s41467-017-02475-3.
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Leung, C;
Hodel, AW;
Brennan, AJ;
Lukoyanova, N;
Tran, S;
House, CM;
Kondos, SC;
... Hoogenboom, BW; + view all
(2017)
Real-time visualization of perforin nanopore assembly.
Nature Nanotechnology
, 12
pp. 467-473.
10.1038/nnano.2016.303.
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Pyne, A;
Pfeil, MP;
Bennett, I;
Ravi, J;
Iavicoli, P;
Lamarre, B;
Roethke, A;
... Ryadnov, MG; + view all
(2017)
Engineering monolayer poration for rapid exfoliation of microbial membranes.
Chemical Science
, 8
(2)
pp. 1105-1115.
10.1039/C6SC02925F.
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Stanley, GJ;
Fassati, A;
Hoogenboom, BW;
(2017)
Biomechanics of the transport barrier in the nuclear pore complex.
Seminars in Cell & Developmental Biology
, 68
pp. 42-51.
10.1016/j.semcdb.2017.05.007.
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2016
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Castelletto, V;
De Santis, E;
Alkassem, H;
Lamarre, B;
Noble, JE;
Ray, S;
Bella, A;
... Ryadnov, MG; + view all
(2016)
Structurally plastic peptide capsules for synthetic antimicrobial viruses.
Chemical Science
, 7
(3)
pp. 1707-1711.
10.1039/c5sc03260a.
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Hodel, AW;
Leung, C;
Dudkina, NV;
Saibil, HR;
Hoogenboom, BW;
(2016)
Atomic force microscopy of membrane pore formation by cholesterol dependent cytolysins.
Current Opinion in Structural Biology
, 39
pp. 8-15.
10.1016/j.sbi.2016.03.005.
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Klejevskaja, B;
Pyne, ALB;
Reynolds, M;
Shivalingam, A;
Thorogate, R;
Hoogenboom, BW;
Ying, L;
(2016)
Studies of G-quadruplexes formed within self-assembled DNA mini-circles.
Chemical Communications
, 52
(84)
pp. 12454-12457.
10.1039/c6cc07110d.
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Lukoyanova, N;
Hoogenboom, BW;
Saibil, HR;
(2016)
The membrane attack complex, perforin and cholesterol-dependent cytolysin superfamily of pore-forming proteins.
Journal of Cell Science
, 129
(11)
pp. 2125-2133.
10.1242/jcs.182741.
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Zahn, R;
Osmanović, D;
Ehret, S;
Araya Callis, C;
Frey, S;
Stewart, M;
You, C;
... Richter, RP; + view all
(2016)
A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies.
Elife
, 5
, Article e14119. 10.7554/eLife.14119.
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2015
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Bestembayeva, A;
Kramer, A;
Labokha, AA;
Osmanović, D;
Liashkovich, I;
Orlova, EV;
Ford, IJ;
... Hoogenboom, BW; + view all
(2015)
Nanoscale stiffness topography reveals structure and mechanics of the transport barrier in intact nuclear pore complexes.
Nature Nanotechnology
, 10
pp. 60-64.
10.1038/nnano.2014.262.
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Cremona, A;
Orsini, F;
Corsetto, PA;
Hoogenboom, BW;
Rizzo, AM;
(2015)
Reversible Dissolution of Microdomains in Detergent-Resistant Membranes at Physiological Temperature.
PLoS One
, 10
(7)
, Article e0132696. 10.1371/journal.pone.0132696.
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Osmanović, D;
Kerr-Winter, M;
Eccleston, RC;
Hoogenboom, BW;
Ford, IJ;
(2015)
Effects of rotational symmetry breaking in polymer-coated nanopores.
Journal of Chemical Physics
, 142
(3)
, Article 034901. 10.1063/1.4905719.
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2014
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Leung, C;
Dudkina, NV;
Lukoyanova, N;
Hodel, AW;
Farabella, I;
Pandurangan, AP;
Jahan, N;
... Hoogenboom, BW; + view all
(2014)
Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin.
Elife
, 3
, Article e04247. 10.7554/eLife.04247.
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Orsini, F;
Santacroce, M;
Cremona, A;
Gosvami, NN;
Lascialfari, A;
Hoogenboom, BW;
(2014)
Atomic force microscopy on plasma membranes from Xenopus laevis oocytes containing human aquaporin 4.
Jornal of Molecular Recognition
, 27
(11)
669 - 675.
10.1002/jmr.2390.
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Pyne, A;
Thompson, R;
Leung, C;
Roy, D;
Hoogenboom, BW;
(2014)
Single-Molecule Reconstruction of Oligonucleotide Secondary Structure by Atomic Force Microscopy.
Small
, 10
(16)
pp. 3257-3261.
10.1002/smll.201400265.
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2013
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Osmanovic, D;
Fassati, A;
Ford, IJ;
Hoogenboom, BW;
(2013)
Physical modelling of the nuclear pore complex.
SOFT MATTER
, 9
(44)
10442 - 10451.
10.1039/c3sm50722j.
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Osmanović, D;
Ford, IJ;
Hoogenboom, BW;
(2013)
Model inspired by nuclear pore complex suggests possible roles for nuclear transport receptors in determining its structure.
Biophys J
, 105
(12)
2781 - 2789.
10.1016/j.bpj.2013.11.013.
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Rakowska, PD;
Jiang, H;
Ray, S;
Pyne, A;
Lamarre, B;
Carr, M;
Judge, PJ;
... Ryadnov, MG; + view all
(2013)
Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers.
Proceedings of the National Academy of Sciences
, 110
(22)
8918 - 8923.
10.1073/pnas.1222824110.
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2012
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Osmanovic, D;
Bailey, J;
Harker, AH;
Fassati, A;
Hoogenboom, BW;
Ford, IJ;
(2012)
Bistable collective behavior of polymers tethered in a nanopore.
Physical Review E
, 85
, Article 061917. 10.1103/PhysRevE.85.061917.
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2009
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Jenkins, N;
Fasano, Y;
Berthod, C;
Maggio-Aprile, I;
Piriou, A;
Giannini, E;
Hoogenboom, BW;
... Fischer, O; + view all
(2009)
Imaging the Essential Role of Spin Fluctuations in High-T-c Superconductivity.
PHYS REV LETT
, 103
(22)
, Article 227001. 10.1103/PhysRevLett.103.227001.
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2006
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DeBeer-Schmitt, L;
Dewhurst, CD;
Hoogenboom, BW;
Petrovic, C;
Eskildsen, MR;
(2006)
Field dependent coherence length in the superclean, high-kappa superconductor CeCoIn5.
PHYS REV LETT
, 97
(12)
, Article 127001. 10.1103/PhysRevLett.97.127001.
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2005
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Hoogenboom, B.W.;
Frederix, P.L.T.;
Yang, J.L.;
Martin, S.;
Pellmont, Y.;
Steinacher, M.;
Zäch, S.;
... Hug, H.J.; + view all
(2005)
A Fabry–Perot interferometer for micrometer-sized cantilevers.
Applied Physics Letters
, 86
(7)
074101-1.
10.1063/1.1866229.
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2003
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Eskildsen, MR;
Dewhurst, CD;
Hoogenboom, BW;
Petrovic, C;
Canfield, PC;
(2003)
Hexagonal and square flux line lattices in CeCoIn5.
PHYS REV LETT
, 90
(18)
, Article 187001. 10.1103/PhysRevLett.90.187001.
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