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Imaging the Effects of Peptide Materials on Phospholipid Membranes by Atomic Force Microscopy

Hammond, K; Benn, G; Bennett, I; Parsons, ES; Ryadnov, MG; Hoogenboom, BW; Pyne, ALB; (2021) Imaging the Effects of Peptide Materials on Phospholipid Membranes by Atomic Force Microscopy. Methods in Molecular Biology , 2208 pp. 225-235. 10.1007/978-1-0716-0928-6_15.

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Hoogenboom_Atomic force microscopy imaging of peptide - 10022020.pdf - Accepted version
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Abstract

Recent advances in biomolecular design require accurate measurements performed in native or near-native environments in real time. Atomic force microscopy (AFM) is a powerful tool to observe the dynamics of biologically relevant processes at aqueous interfaces with high spatial resolution. Here, we describe imaging protocols to characterize the effects of peptide materials on phospholipid membranes in solution by AFM. These protocols can be used to determine the mechanism and kinetics of membrane-associated activities at the nanoscale.

Type: Article
Title: Imaging the Effects of Peptide Materials on Phospholipid Membranes by Atomic Force Microscopy
Location: United States
DOI: 10.1007/978-1-0716-0928-6_15
Publisher version: http://dx.doi.org/10.1007/978-1-0716-0928-6_15
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Antimicrobial peptides, Atomic force microscopy, Peptide materials, Phospholipid membranes, Supported lipid bilayers
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Physics and Astronomy
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > London Centre for Nanotechnology
UCL > Provost and Vice Provost Offices > VP: Research
URI: https://discovery.ucl.ac.uk/id/eprint/10114164
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