Hammond, K;
Benn, G;
Bennett, I;
Parsons, ES;
Ryadnov, MG;
Hoogenboom, BW;
Pyne, ALB;
(2021)
Imaging the Effects of Peptide Materials on Phospholipid Membranes by Atomic Force Microscopy.
Methods in Molecular Biology
, 2208
pp. 225-235.
10.1007/978-1-0716-0928-6_15.
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Abstract
Recent advances in biomolecular design require accurate measurements performed in native or near-native environments in real time. Atomic force microscopy (AFM) is a powerful tool to observe the dynamics of biologically relevant processes at aqueous interfaces with high spatial resolution. Here, we describe imaging protocols to characterize the effects of peptide materials on phospholipid membranes in solution by AFM. These protocols can be used to determine the mechanism and kinetics of membrane-associated activities at the nanoscale.
| Type: | Article |
|---|---|
| Title: | Imaging the Effects of Peptide Materials on Phospholipid Membranes by Atomic Force Microscopy |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/978-1-0716-0928-6_15 |
| Publisher version: | http://dx.doi.org/10.1007/978-1-0716-0928-6_15 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Antimicrobial peptides, Atomic force microscopy, Peptide materials, Phospholipid membranes, Supported lipid bilayers |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Physics and Astronomy UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > London Centre for Nanotechnology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10114164 |
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