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Number of items: 121.
Article
Abis, G;
Charles, RL;
Eaton, P;
Conte, MR;
(2019)
Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain.
Protein Expression and Purification
, 153
pp. 105-113.
10.1016/j.pep.2018.09.001.
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Abis, G;
Charles, RL;
Kopec, J;
Yue, WW;
Atkinson, RA;
Bui, TTT;
Lynham, S;
... Conte, MR; + view all
(2019)
15-deoxy-Δ12,14-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism.
Communications Biology
, 2
, Article 188. 10.1038/s42003-019-0426-2.
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Abis, G;
Pacheco-Gomez, R;
Bui, TT;
Conte, MR;
(2019)
Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase.
Analytical Chemistry
, 91
(23)
pp. 14865-14872.
10.1021/acs.analchem.9b01847.
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Acton, O;
Grant, T;
Nicastro, G;
Ball, NJ;
Goldstone, DC;
Robertson, LE;
Sader, K;
... Rosenthal, PB; + view all
(2019)
Structural basis for Fullerene geometry in a human endogenous retrovirus capsid.
Nature Communications
, 10
, Article 5822. 10.1038/s41467-019-13786-y.
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Adib, R;
Montgomery, JM;
Atherton, J;
O'Regan, L;
Richards, MW;
Straatman, KR;
Roth, D;
... Fry, AM; + view all
(2019)
Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression.
Science Signaling
, 12
(594)
, Article eaaw2939. 10.1126/scisignal.aaw2939.
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Ahmed, AA;
Luo, CJ;
Perez-Garrido, S;
Browse, CR;
Thrasivoulou, C;
Stoyanov, SD;
Smoukov, SK;
(2019)
3D cancer cell culture in high‐yield multi‐scale scaffolds by shear spinning.
Biotechnology Progress
, 35
(2)
, Article e2750. 10.1002/btpr.2750.
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Akter, R;
Zhyvoloup, A;
Zheng, B;
Bhatia, SR;
Raleigh, DP;
(2019)
The triphenylmethane dye brilliant blue G is only moderately effective at inhibiting amyloid formation by human amylin or at disaggregating amylin amyloid fibrils, but interferes with amyloid assays; Implications for inhibitor design.
PLoS One
, 14
(8)
, Article e0219130. 10.1371/journal.pone.0219130.
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Aloum, L;
Brimson, CA;
Zhyvoloup, A;
Baines, R;
Baković, J;
Filonenko, V;
Thompson, CRL;
(2019)
Coenzyme A and protein CoAlation levels are regulated in response to oxidative stress and during morphogenesis in Dictyostelium discoideum.
Biochemical and Biophysical Research Communications
, 511
(2)
pp. 294-299.
10.1016/j.bbrc.2019.02.031.
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Arnvig, K;
(2019)
Riboswitches: choosing the best platform.
[Review].
Biochemical Society Transactions
, 47
(4)
pp. 1091-1099.
10.1042/BST20180507.
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Ashford, P;
Pang, CSM;
Moya-García, AA;
Adeyelu, T;
Orengo, CA;
(2019)
A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations.
Scientific Reports
, 9
, Article 263. 10.1038/s41598-018-36401-4.
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Backer, AS;
Biebricher, AS;
King, GA;
Wuite, GJL;
Heller, I;
Peterman, EJG;
(2019)
Single-molecule polarization microscopy of DNA intercalators sheds light on the structure of S-DNA.
Science Advances
, 5
(3)
, Article eaav1083. 10.1126/sciadv.aav1083.
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Baskozos, G;
Dawes, JM;
Austin, JS;
Antunes-Martins, A;
McDermott, L;
Clark, AJ;
Trendafilova, T;
... Bennett, DL; + view all
(2019)
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury.
Pain
, 160
(2)
pp. 463-485.
10.1097/j.pain.0000000000001416.
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Biancospino, M;
Buel, GR;
Niño, CA;
Maspero, E;
di Perrotolo, RS;
Raimondi, A;
Redlingshöfer, L;
... Polo, S; + view all
(2019)
Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension.
Nature Communications
, 10
(1)
, Article 4974. 10.1038/s41467-019-12855-6.
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Björck, ML;
Vilhjálmsdóttir, J;
Hartley, AM;
Meunier, B;
Näsvik Öjemyr, L;
Maréchal, A;
Brzezinski, P;
(2019)
Proton-transfer pathways in the mitochondrial S. cerevisiae cytochrome c oxidase.
Scientific Reports
, 9
, Article 20207. 10.1038/s41598-019-56648-9.
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Blombach, F;
Matelska, D;
Fouqueau, T;
Cackett, G;
Werner, F;
(2019)
Key Concepts and Challenges in Archaeal Transcription.
Journal of Molecular Biology
, 431
(20)
pp. 4184-4201.
10.1016/j.jmb.2019.06.020.
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Bowers, K;
(2019)
RNA Interference-Mediated Inhibition of ESCRT in Mammalian Cells.
Methods in Molecular Biology
, 1998
pp. 305-318.
10.1007/978-1-4939-9492-2_22.
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Britt, HM;
García-Herrero, CA;
Denny, PW;
Mosely, JA;
Sanderson, JM;
(2019)
Lytic reactions of drugs with lipid membranes.
Chemical Science
, 10
(3)
pp. 674-680.
10.1039/c8sc04831b.
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Britt, HM;
Mosely, JA;
Sanderson, JM;
(2019)
The influence of cholesterol on melittin lipidation in neutral membranes.
Physical Chemistry Chemical Physics
, 21
(2)
pp. 631-640.
10.1039/c8cp06661b.
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Burnham, DR;
Kose, HB;
Hoyle, RB;
Yardimci, H;
(2019)
The mechanism of DNA unwinding by the eukaryotic replicative helicase.
Nature Communications
, 10
, Article 2159. 10.1038/s41467-019-09896-2.
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Camus, SM;
Camus, MD;
Figueras-Novoa, C;
Boncompain, G;
Sadacca, LA;
Esk, C;
Bigot, A;
... Brodsky, FM; + view all
(2019)
CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis.
Journal of Cell Biology
, 219
(1)
, Article e201812135. 10.1083/jcb.201812135.
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Caratti, G;
Poolman, T;
Hurst, RJ;
Ince, L;
Knight, A;
Krakowiak, K;
Durrington, HJ;
... Ray, DW; + view all
(2019)
Caveolin1 interacts with the glucocorticoid receptor in the lung but is dispensable for its anti-inflammatory actions in lung inflammation and Trichuris Muris infection.
Scientific Reports
, 9
, Article 8581. 10.1038/s41598-019-44963-0.
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Carnevali, PBM;
Schulz, F;
Castelle, C;
Kantor, R;
Shih, P;
Sharon, I;
Santini, JM;
... Banfield, JF; + view all
(2019)
Hydrogen-based metabolism as an ancestral trait in lineages sibling to the Cyanobacteria.
Nature Communications
, 10
, Article 463. 10.1038/s41467-018-08246-y.
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Castaño-Díez, D;
Zanetti, G;
(2019)
In situ structure determination by subtomogram averaging.
Current Opinion in Structural Biology
, 58
pp. 68-75.
10.1016/j.sbi.2019.05.011.
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Changko, S;
Rajakumar, PD;
Young, REB;
Purton, S;
(2019)
The phosphite oxidoreductase gene, ptxD as a bio-contained chloroplast marker and crop-protection tool for algal biotechnology using Chlamydomonas.
Applied Microbiology and Biotechnology
10.1007/s00253-019-10258-7.
(In press).
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Chelban, V;
Wilson, MP;
Warman Chardon, J;
Vandrovcova, J;
Zanetti, MN;
Zamba-Papanicolaou, E;
Efthymiou, S;
... SYNaPS Study Group, .; + view all
(2019)
PDXK mutations cause polyneuropathy responsive to PLP supplementation.
Annals of Neurology
10.1002/ana.25524.
(In press).
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Cheung, ACM;
(2019)
Building transcription complexes.
Nature Structural & Molecular Biology
, 26
(1-2)
10.1038/s41594-018-0174-x.
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Codina, N;
Hilton, D;
Zhang, C;
Chakroun, N;
Ahmad, SS;
Perkins, SJ;
Dalby, PA;
(2019)
An Expanded Conformation of an Antibody Fab Region by X-Ray Scattering, Molecular Dynamics and smFRET Identifies an Aggregation Mechanism.
Journal of Molecular Biology
10.1016/j.jmb.2019.02.009.
(In press).
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Corazza, A;
Verona, G;
Waudby, CA;
Mangione, PP;
Bingham, RP;
Uings, I;
Canetti, D;
... Bellotti, V; + view all
(2019)
Binding of monovalent and bivalent ligands by transthyretin causes different short and long distance conformational changes.
Journal of Medicinal Chemistry
, 62
(17)
pp. 8274-8283.
10.1021/acs.jmedchem.9b01037.
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Creary, LE;
Guerra, SG;
Chong, W;
Brown, CJ;
Turner, TR;
Robinson, J;
Bultitude, WP;
... Fernandez-Vina, MA; + view all
(2019)
Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-lymphoblastoid cell lines: Report from the 17th International HLA and Immunogenetics Workshop.
Human Immunology
, 80
(7)
pp. 449-460.
10.1016/j.humimm.2019.03.001.
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Dagil, L;
Troelsen, KS;
Bolt, G;
Thim, L;
Wu, B;
Zhao, X;
Tuddenham, EGD;
... Hansen, DF; + view all
(2019)
Interaction Between the a3 Region of Factor VIII and the TIL'E’ Domains of the von Willebrand Factor.
Biophysical Journal
, 117
(3)
pp. 479-489.
10.1016/j.bpj.2019.07.007.
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Dagil, R;
Ball, NJ;
Ogrodowicz, RW;
Hobor, F;
Purkiss, AG;
Kelly, G;
Martin, SR;
... Ramos, A; + view all
(2019)
IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties.
Nucleic Acids Research
, Article gkz136. 10.1093/nar/gkz136.
(In press).
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Deville, C;
Franke, K;
Mogk, A;
Bukau, B;
Saibil, HR;
(2019)
Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Cell Reports
, 27
(12)
3433-3446.e4.
10.1016/j.celrep.2019.05.075.
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Devoto, A;
Santini, JM;
Olm, M;
Anantharaman, K;
Munk, P;
Archie, E;
Turnbaugh, P;
... Banfield, J; + view all
(2019)
Megaphages infect Prevotella and variants are widespread in gut microbiomes.
Nature Microbiology
, 4
pp. 693-700.
10.1038/s41564-018-0338-9.
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Dickman, R;
Danelius, E;
Mitchell, SA;
Hansen, DF;
Erdélyi, M;
Tabor, AB;
(2019)
A Chemical Biology Approach to Understanding Molecular Recognition of Lipid II by Nisin(1-12): Synthesis and NMR Ensemble Analysis of Nisin(1-12) and Analogues.
Chemistry
10.1002/chem.201902814.
(In press).
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Dickman, R;
Mitchell, SA;
Figueiredo, AM;
Hansen, DF;
Tabor, AB;
(2019)
Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B.
The Journal of Organic Chemistry
, 84
(18)
pp. 11493-11512.
10.1021/acs.joc.9b01253.
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Djordjevic, S;
(2019)
Proteins that sense cellular environments – examples and implications.
[Review].
Biologia Serbica
, 41
(2)
pp. 19-26.
10.5281/zenodo.3532059.
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Dobrijevic, D;
Benhamou, L;
Aliev, AE;
Méndez-Sánchez, D;
Dawson, N;
Baud, D;
Tappertzhofen, N;
... Ward, JM; + view all
(2019)
Metagenomic ene-reductases for the bioreduction of sterically challenging enones.
RSC Advances
, 9
(63)
pp. 36608-36614.
10.1039/c9ra06088j.
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Eickhoff, P;
Kose, HB;
Martino, F;
Petojevic, T;
Abid Ali, F;
Locke, J;
Tamberg, N;
... Costa, A; + view all
(2019)
Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
Cell Reports
, 28
(10)
2673-2688.e8.
10.1016/j.celrep.2019.07.104.
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Eldrid, CFS;
Ujma, J;
Kalfas, S;
Tomczyk, N;
Giles, K;
Morris, MR;
Thalassinos, K;
(2019)
Gas Phase Stability of Protein Ions in a Cyclic Ion Mobility Spectrometry Traveling Wave Device.
Analytical Chemistry
10.1021/acs.analchem.8b05641.
(In press).
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Fedorec, AJH;
Ozdemir, T;
Doshi, A;
Ho, Y-K;
Rosa, L;
Rutter, J;
Velazquez, O;
... Barnes, CP; + view all
(2019)
Two New Plasmid Post-segregational Killing Mechanisms for the Implementation of Synthetic Gene Networks in Escherichia coli.
iScience
10.1016/j.isci.2019.03.019.
(In press).
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Ferdous, S;
Kelm, S;
Baker, TS;
Shi, J;
Martin, A;
(2019)
B-cell epitopes: Discontinuity and conformational analysis.
Molecular Immunology
, 114
pp. 643-650.
10.1016/j.molimm.2019.09.014.
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Fitzpatrick, AW;
Saibil, HR;
(2019)
Cryo-EM of amyloid fibrils and cellular aggregates.
Current Opinion in Structural Biology
, 58
pp. 34-42.
10.1016/j.sbi.2019.05.003.
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Fumagalli, M;
Camus, SM;
Diekmann, Y;
Burke, A;
Camus, M;
Norman, P;
Joseph, A;
... Brodsky, F; + view all
(2019)
Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism.
eLife
, 2019
(8)
, Article e41517. 10.7554/eLife.41517.
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Gabelica, V;
Shvartsburg, AA;
Afonso, C;
Barran, P;
Benesch, JLP;
Bleiholder, C;
Bowers, MT;
... Wyttenbach, T; + view all
(2019)
Recommendations for reporting ion mobility Mass Spectrometry measurements.
Mass Spectrometry Review
10.1002/mas.21585.
(In press).
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Gout, I;
(2019)
Coenzyme A: a protective thiol in bacterial antioxidant defence.
Biochemical Society Transactions
, 47
(1)
pp. 469-476.
10.1042/BST20180415.
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Hansen, DF;
(2019)
Using Deep Neural Networks to Reconstruct Non-uniformly Sampled NMR Spectra.
Journal of Biomolecular NMR
10.1007/s10858-019-00265-1.
(In press).
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Hartley, AM;
Lukoyanova, N;
Zhang, Y;
Cabrera-Orefice, A;
Arnold, S;
Meunier, B;
Pinotsis, N;
(2019)
Structure of yeast cytochrome c oxidase in a supercomplex with cytochrome bc1.
Nature Structural and Molecular Biology
, 26
pp. 78-83.
10.1038/s41594-018-0172-z.
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Heifetz, A;
James, T;
Southey, M;
Morao, I;
Aldeghi, M;
Sarrat, L;
Fedorov, DG;
... Townsend-Nicholson, A; + view all
(2019)
Characterising GPCR–ligand interactions using a fragment molecular orbital-based approach.
Current Opinion in Structural Biology
, 55
pp. 85-92.
10.1016/j.sbi.2019.03.021.
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Ho, BT;
(2019)
From Wall to Wall: How the Type 6 Secretion System Knows To Stop Growing.
Journal of Bacteriology
10.1128/JB.00647-19.
(In press).
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Hospenthal, MK;
Waksman, G;
(2019)
The Remarkable Biomechanical Properties of the Type 1 Chaperone-Usher Pilus: A Structural and Molecular Perspective.
Microbiology Spectrum
, 7
(1)
pp. 1-10.
10.1128/microbiolspec.PSIB-0010-2018.
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Hui, GK;
Gardener, AD;
Begum, H;
Eldrid, C;
Thalassinos, K;
Gor, J;
Perkins, SJ;
(2019)
The solution structure of the human IgG2 subclass is distinct from those for human IgG1 and IgG4 providing an explanation for their discrete functions.
Journal of Biological Chemistry
10.1074/jbc.RA118.007134.
(In press).
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Hunter, AL;
Narang, N;
Baxter, M;
Ray, DW;
Poolman, TM;
(2019)
An improved method for quantitative ChIP studies of nuclear receptor function.
Journal of Molecular Endocrinology
, 62
(4)
pp. 169-177.
10.1530/JME-18-0243.
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Ignatiou, A;
Brasiles, S;
Fadel, MES;
Buerger, J;
Mielke, T;
Topf, M;
Tavares, P;
(2019)
Structural transitions during the scaffolding-driven assembly of a viral capsid.
Nature Communications
, 10
, Article 4840. 10.1038/s41467-019-12790-6.
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Ireland, S;
Martin, ACR;
(2019)
ZincBind - The Database of Zinc Binding Sites.
Database : the Journal of Biological Databases and Curation
, 2019
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James, JMB;
Cryar, A;
Thalassinos, K;
(2019)
Optimization Workflow for the Analysis of Cross-Linked Peptides Using a Quadrupole Time-of-Flight Mass Spectrometer.
Analytical Chemistry
, 91
(3)
pp. 1808-1814.
10.1021/acs.analchem.8b02319.
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Jordan, SF;
Rammu, H;
Zheludev, IN;
Hartley, AM;
Maréchal, A;
Lane, N;
(2019)
Promotion of protocell self-assembly from mixed amphiphiles at the origin of life.
Nature Ecology & Evolution
, 3
pp. 1705-1714.
10.1038/s41559-019-1015-y.
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King, GA;
Burla, F;
Peterman, EJG;
Wuite, GJL;
(2019)
Supercoiling DNA optically.
Proceedings of the National Academy of Sciences (PNAS)
, 116
(52)
pp. 26534-26539.
10.1073/pnas.1908826116.
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Koehler, L;
Ruiz-Gomez, G;
Balamurugan, K;
Rother, S;
Freyse, J;
Moeller, S;
Schnabelrauch, M;
... Hintze, V; + view all
(2019)
Dual Action of Sulfated Hyaluronan on Angiogenic Processes in Relation to Vascular Endothelial Growth Factor-A.
Scientific Reports
, 9
, Article 18143. 10.1038/s41598-019-54211-0.
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Kose, HB;
Larsen, NB;
Duxin, JP;
Yardimci, H;
(2019)
Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model.
Cell Reports
, 26
(8)
2113-2125.e6.
10.1016/j.celrep.2019.01.086.
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Kuzmanic, A;
Pritchard, RB;
Hansen, DF;
Gervasio, FL;
(2019)
Importance of the Force Field Choice in Capturing Functionally Relevant Dynamics in the von Willebrand Factor.
The Journal of Physical Chemistry Letters
, 10
(8)
pp. 1928-1934.
10.1021/acs.jpclett.9b00517.
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Lau, A;
Zahid, H;
Gor, J;
Perkins, S;
Coker, A;
McDermott, L;
(2019)
Crystal structure of human zinc-α2- glycoprotein in complex with fatty acid reveals multiple different modes of lipid binding.
Biochemical Journal
, 476
(19)
pp. 2815-2834.
10.1042/BCJ20190354.
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Lesjak, M;
Balesaria, S;
Skinner, V;
Debnam, ES;
Srai, SKS;
(2019)
Quercetin inhibits intestinal non-haem iron absorption by regulating iron metabolism genes in the tissues.
European Journal of Nutrition
, 58
pp. 743-753.
10.1007/s00394-018-1680-7.
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Lesjak, M;
Srai, SKS;
(2019)
Role of Dietary Flavonoids in Iron Homeostasis.
Pharmaceuticals
, 12
(3)
, Article 119. 10.3390/ph12030119.
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Lherbette, M;
Redlingshöfer, L;
Brodsky, FM;
Schaap, IAT;
Dannhauser, PN;
(2019)
The AP2 adaptor enhances clathrin coat stiffness.
The FEBS Journal
, 286
(20)
pp. 4074-4085.
10.1111/febs.14961.
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Mackenzie, HW;
Flemming Hansen, D;
(2019)
Arginine Side-Chain Hydrogen Exchange: Quantifying Arginine Side-Chain Interactions in Solution.
ChemPhysChem
, 20
(2)
, Article Special Issue: BioNMR Spectroscopy. 10.1002/cphc.201800598.
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Magno, L;
Lessard, CB;
Martins, M;
Lang, V;
Cruz, P;
Asi, Y;
Katan, M;
... Whiting, PJ; + view all
(2019)
Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph.
Alzheimer's Research & Therapy
, 11
, Article 16. 10.1186/s13195-019-0469-0.
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Maitra, A;
Munshi, T;
Healy, J;
Martin, LT;
Vollmer, W;
Keep, NH;
Bhakta, S;
(2019)
Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles' heel for the TB-causing pathogen.
FEMS Microbiology Reviews
, 43
(5)
pp. 548-575.
10.1093/femsre/fuz016.
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Malerba, A;
Klein, P;
Lu-Nguyen, N;
Cappellari, O;
Strings-Ufombah, V;
Harbaran, S;
Roelvink, P;
... Dickson, G; + view all
(2019)
Established PABPN1 intranuclear inclusions in OPMD muscle can be efficiently reversed by AAV-mediated knock-down and replacement of mutant expanded PABPN1.
Human Molecular Genetics
, 28
(19)
pp. 3301-3308.
10.1093/hmg/ddz167.
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Malkamäki, A;
Meunier, B;
Reidelbach, M;
Rich, PR;
Sharma, V;
(2019)
The H channel is not a proton transfer path in yeast cytochrome c oxidase.
Biochimica et Biophysica Acta (BBA) - Bioenergetics
, 1860
(9)
pp. 717-723.
10.1016/j.bbabio.2019.07.012.
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Marabelli, C;
Marrocco, B;
Pilotto, S;
Chittori, S;
Picaud, S;
Marchese, S;
Ciossani, G;
... Mattevi, A; + view all
(2019)
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
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Cold Spring Harbor Laboratory Press
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Conference item
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Camus, SM;
Camus, MD;
Figueras-Novoa, C;
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Gould, GW;
Kioumourtzoglou, D;
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Clathrin heavy chain 22 controls biogenesis of the human glucose transporter 4 storage compartment from the early secretory pathway.
Presented at: Diabetes UK Professional Conference 2019, Liverpool, UK.
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Thesis
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Da Costa Ramos, Juliana;
(2019)
The algal chloroplast as a platform for synthesis of lytic enzymes targeting Gram-negative pathogens.
Doctoral thesis (Ph.D), UCL (University College London).
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Yon, Alexander Robert;
(2019)
Single-molecule Study of Antibody Drug Binding to Cell Surface Receptors.
Doctoral thesis (Ph.D), UCL (University College London).
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