Browse by UCL people
Group by: Type | Date
Number of items: 45.
2020
Madan, JJ;
Rosu, L;
Tefera, MG;
van Rensburg, C;
Evans, D;
Langley, I;
Tomeny, EM;
... Squire, SB; + view all
(2020)
Economic evaluation of short treatment for multidrug-resistant tuberculosis, Ethiopia and South Africa: the STREAM trial.
Bulletin of the World Health Organization
, 98
(5)
pp. 306-314.
10.2471/blt.19.243584.
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Phillips, PPJ;
Van Deun, A;
Ahmed, S;
Goodall, RL;
Meredith, SK;
Conradie, F;
Chiang, C-Y;
... Nunn, AJ; + view all
(2020)
Investigation of the efficacy of the short regimen for rifampicin-resistant TB from the STREAM trial.
BMC Medicine
, 18
, Article 314. 10.1186/s12916-020-01770-z.
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2019
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Morris, TP;
Jarvis, CI;
Cragg, W;
Phillips, PPJ;
Choodari-Oskooei, B;
Sydes, MR;
(2019)
Proposals on Kaplan–Meier plots in medical research and a survey of stakeholder views: KMunicate.
BMJ Open
, 9
(9)
, Article e030215. 10.1136/bmjopen-2019-030215.
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Nunn, AJ;
Phillips, PPJ;
Meredith, SK;
Chiang, C-Y;
Conradie, F;
Dalai, D;
van Deun, A;
... STREAM Study Collaborators, .; + view all
(2019)
A Trial of a Shorter Regimen for Rifampin-Resistant Tuberculosis.
The New England Journal of Medicine
, 380
(13)
pp. 1201-1213.
10.1056/NEJMoa1811867.
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Phillips, PPJ;
Mitnick, CD;
Neaton, JD;
Nahid, P;
Lienhardt, C;
Nunn, AJ;
(2019)
Keeping phase III tuberculosis trials relevant: Adapting to a rapidly changing landscape.
PLOS Medicine
, 16
(3)
, Article e1002767. 10.1371/journal.pmed.1002767.
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Stagg, HR;
Bothamley, GH;
Davidson, JA;
Kunst, H;
Lalor, MK;
Lipman, MC;
Loutet, MG;
... London INH-R TB study group; + view all
(2019)
Fluoroquinolones and isoniazid resistant TB: implications for the 2018 WHO guidance.
European Respiratory Journal
, 54
(4)
, Article 1900982. 10.1183/13993003.00982-2019.
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Tweed, CD;
Crook, AM;
Dawson, R;
Diacon, AH;
McHugh, TD;
Mendel, CM;
Meredith, SK;
... Gillespie, SH; + view all
(2019)
Toxicity related to standard TB therapy for pulmonary tuberculosis and treatment outcomes in the REMoxTB study according to HIV status.
BMC Pulmonary Medicine
, 19
(1)
, Article 152. 10.1186/s12890-019-0907-6.
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2018
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Fregonese, F;
Ahuja, SD;
Akkerman, OW;
Arakaki-Sanchez, D;
Ayakaka, I;
Baghaei, P;
Bang, D;
... Menzies, D; + view all
(2018)
Comparison of different treatments for isoniazid-resistant tuberculosis: an individual patient data meta-analysis.
The Lancet Respiratory Medicine
, 6
(4)
pp. 265-275.
10.1016/S2213-2600(18)30078-X.
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Murthy, SE;
Chatterjee, F;
Crook, A;
Dawson, R;
Mendel, C;
Murphy, ME;
Murray, SR;
... Gillespie, SH; + view all
(2018)
Pretreatment chest x-ray severity and its relation to bacterial burden in smear positive pulmonary tuberculosis.
BMC Medicine
, 16
(1)
, Article 73. 10.1186/s12916-018-1053-3.
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Quartagno, M;
Walker, AS;
Carpenter, J;
Phillips, P;
Parmar, M;
(2018)
Rethinking non-inferiority: a practical trial design for optimising treatment duration.
Clinical Trials
, 15
(5)
pp. 477-488.
10.1177/1740774518778027.
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Tweed, CD;
Crook, AM;
Amukoye, EI;
Dawson, R;
Diacon, AH;
Hanekom, M;
McHugh, TD;
... Gillespie, SH; + view all
(2018)
Toxicity associated with tuberculosis chemotherapy in the REMoxTB study.
BMC Infectious Diseases
, 18
, Article 317. 10.1186/s12879-018-3230-6.
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Tweed, CD;
Wills, GH;
Crook, AM;
Dawson, R;
Diacon, AH;
Louw, CE;
McHugh, TD;
... Gillespie, SH; + view all
(2018)
Liver toxicity associated with tuberculosis chemotherapy in the REMoxTB study.
BMC Medicine
, 16
(1)
, Article 46. 10.1186/s12916-018-1033-7.
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2017
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Bouton, TC;
Phillips, PPJ;
Mitnick, CD;
Peloquin, CA;
Eisenach, K;
Patientia, RF;
Lecca, L;
... Horsburgh, CR; + view all
(2017)
An optimized background regimen design to evaluate the contribution of levofloxacin to multidrug-resistant tuberculosis treatment regimens: study protocol for a randomized controlled trial.
Trials
, 18
, Article 563. 10.1186/s13063-017-2292-x.
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Murphy, ME;
Phillips, PJ;
Mendel, CM;
Bongard, E;
Bateson, AL;
Hunt, R;
Murthy, S;
... Lipman, M; + view all
(2017)
Spot sputum samples are at least as good as early morning samples for identifying Mycobacterium tuberculosis.
BMC Medicine
, 15
, Article 192. 10.1186/s12916-017-0947-9.
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Phillips, PPJ;
(2017)
Setting tuberculosis regimen development on a firm foundation.
Clinical Infectious Diseases
, 65
(1)
pp. 55-56.
10.1093/cid/cix250.
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Phillips, PPJ;
Mendel, CM;
Nunn, AJ;
McHugh, TD;
Crook, AM;
Hunt, R;
Bateson, A;
(2017)
A comparison of liquid and solid culture for determining relapse and durable cure in phase III TB trials for new regimens.
BMC Medicine
, 15
, Article 207. 10.1186/s12916-017-0955-9.
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Witney, AA;
Bateson, ALE;
Jindani, A;
Phillips, PPJ;
Coleman, D;
Stoker, NG;
Butcher, PD;
(2017)
Use of whole-genome sequencing to distinguish relapse from reinfection in a completed tuberculosis clinical trial.
BMC Medicine
, 15
, Article 71. 10.1186/s12916-017-0834-4.
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2016
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Berry, C;
Yates, TA;
Seddon, JA;
Phillips, PP;
du Cros, P;
North London TB Journal Club;
(2016)
Efficacy, safety and tolerability of linezolid for the treatment of XDR-TB: a study in China.
European Respiratory Journal
, 47
(5)
pp. 1591-1592.
10.1183/13993003.01646-2015.
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Boeree, MJ;
Heinrich, H;
Rehal, S;
Phillips, PPJ;
(2016)
High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial.
Lancet Infectious Diseases
, 17
(1)
pp. 39-49.
10.1016/S1473-3099(16)30274-2.
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Bratton, DJ;
Parmar, MK;
Phillips, PP;
Choodari-Oskooei, B;
(2016)
Type I error rates of multi-arm multi-stage clinical trials: strong control and impact of intermediate outcomes.
Trials
, 17
, Article 309. 10.1186/s13063-016-1382-5.
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Dooley, KE;
Phillips, PP;
Nahid, P;
Hoelscher, M;
(2016)
Challenges in the clinical assessment of novel tuberculosis drugs.
Advanced Drug Delivery Reviews
, 102
pp. 116-122.
10.1016/j.addr.2016.01.014.
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Eliseev, P;
Balantcev, G;
Nikishova, E;
Gaida, A;
Bogdanova, E;
Enarson, D;
Ornstein, T;
... Mariandyshev, A; + view all
(2016)
The Impact of a Line Probe Assay Based Diagnostic Algorithm on Time to Treatment Initiation and Treatment Outcomes for Multidrug Resistant TB Patients in Arkhangelsk Region, Russia.
PLOS One
, 11
(4)
, Article e0152761. 10.1371/journal.pone.0152761.
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Furin, J;
Alirol, E;
Allen, E;
Fielding, K;
Merle, C;
Abubakar, I;
Andersen, J;
... Du Cros, P; + view all
(2016)
Drug-resistant tuberculosis clinical trials: Proposed core research definitions in adults.
International Journal of Tuberculosis and Lung Disease
, 20
(3)
pp. 290-294.
10.5588/ijtld.15.0490.
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Knapp, M;
King, D;
Romeo, R;
Adams, J;
Baldwin, A;
Ballard, C;
Banerjee, S;
... Howard, R; + view all
(2016)
Cost-effectiveness of donepezil and memantine in moderate to severe Alzheimer’s disease (the DOMINO-AD trial).
International Journal of Geriatric Psychiatry
10.1002/gps.4583.
(In press).
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Papineni, P;
Phillips, P;
Lu, Q;
Cheung, YB;
Nunn, A;
Paton, N;
(2016)
TRUNCATE-TB: an innovative trial design for drug-sensitive tuberculosis.
International Journal of Infectious Diseases
, 45
p. 404.
10.1016/j.ijid.2016.02.863.
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Phillips, Patrick PJ;
Nunn, Andrew J;
(2016)
Clinical Trials.
In: Abubakar, I and Stagg, HR and Cohen, T and Rodrigues, LC, (eds.)
Infectious Disease Epidemiology.
(pp. 71-86).
Oxford University Press: Oxford, United Kingdom.
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Phillips, PP;
Dooley, KE;
Gillespie, SH;
Heinrich, N;
Stout, JE;
Nahid, P;
Diacon, AH;
... Hoelscher, M; + view all
(2016)
A new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP).
BMC Medicine
, 14
, Article 51. 10.1186/s12916-016-0597-3.
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Phillips, PP;
Fletcher, HA;
Abubakar, I;
Lipman, MC;
McHugh, TD;
(2016)
World TB Day 2016: an interview with leading experts in tuberculosis research.
BMC Medicine
, 14
, Article 55. 10.1186/s12916-016-0591-9.
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Phillips, PP;
Mendel, CM;
Burger, DA;
Crook, A;
Nunn, AJ;
Dawson, R;
Diacon, AH;
(2016)
Limited role of culture conversion for decision-making in individual patient care and for advancing novel regimens to confirmatory clinical trials.
BMC Med
, 14
(1)
, Article 19. 10.1186/s12916-016-0565-y.
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Phillips, PP;
Mendel, CM;
Burger, DA;
Crook, AM;
Nunn, AJ;
Dawson, R;
Diacon, AH;
(2016)
Erratum to: Limited role of culture conversion for decision-making in individual patient care and for advancing novel regimens to confirmatory clinical trials.
[Corrigendum].
BMC Medicine
, 14
(1)
, Article 36. 10.1186/s12916-016-0585-7.
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Phillips, PPJ;
(2016)
Methodological considerations in clinical trials for new MDR-TB treatment regimens.
The International Journal of Tuberculosis and Lung Disease
, 20
(S1)
S4-S7.
10.5588/ijtld.16.0061.
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Rehal, S;
Morris, TP;
Fielding, K;
Carpenter, JR;
Phillips, PPJ;
(2016)
Non-inferiority trials: are they inferior? A systematic review of reporting in major medical journals.
BMJ Open
, 6
(10)
, Article e012594. 10.1136/bmjopen-2016-012594.
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2015
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Howard, R;
McShane, R;
Lindesay, J;
Ritchie, C;
Baldwin, A;
Barber, R;
Burns, A;
... Phillips, PP; + view all
(2015)
Nursing home placement in the Donepezil and Memantine in Moderate to Severe Alzheimer's Disease (DOMINO-AD) trial: secondary and post-hoc analyses.
The Lancet Neurology
, 14
(12)
pp. 1171-1181.
10.1016/S1474-4422(15)00258-6.
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Nimmo, C;
Lipman, M;
Phillips, PPJ;
McHugh, T;
Nunn, A;
Abubakar, I;
(2015)
Shortening treatment of tuberculosis: lessons from fluoroquinolone trials.
The Lancet Infectious Diseases
, 15
(2)
pp. 141-143.
10.1016/S1473-3099(14)70885-0.
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Phillips, PP;
Morris, TP;
Walker, AS;
(2015)
DOOR/RADAR: A Gateway Into the Unknown?
[Letter].
Clinical Infectious Diseases
10.1093/cid/civ1002.
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2014
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Gillespie, SH;
Crook, AM;
McHugh, TD;
Mendel, CM;
Meredith, SK;
Murray, SR;
Pappas, F;
... REMoxTB, Consortium; + view all
(2014)
Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis.
New England Journal of Medicine
, 371
(17)
pp. 1577-1587.
10.1056/NEJMoa1407426.
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Jindani, A;
Harrison, TS;
Nunn, AJ;
Phillips, PP;
Churchyard, GJ;
Charalambous, S;
Hatherill, M;
... RIFAQUIN Trial, Team; + view all
(2014)
High-dose rifapentine with moxifloxacin for pulmonary tuberculosis.
New England Journal of Medicine
, 371
(17)
pp. 1599-1608.
10.1056/NEJMoa1314210.
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Nunn, AJ;
Rusen, ID;
Van Deun, A;
Torrea, G;
Phillips, PJP;
Chiang, C-Y;
Squire, SB;
... Meredith, SK; + view all
(2014)
The Evaluation of a Standardised Treatment Regimen of anti-Tuberculosis Drugs for Patients with MDR-TB (STREAM): study protocol for a randomised controlled trial.
Trials
, 15
(Septem)
, Article 353. 10.1186/1745-6215-15-353.
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2013
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Bratton, DJ;
Phillips, PP;
Parmar, MK;
(2013)
A multi-arm multi-stage clinical trial design for binary outcomes with application to tuberculosis.
BMC Medical Research Methodology
, 13
, Article 139. 10.1186/1471-2288-13-139.
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Friedrich, SO;
Rachow, A;
Saathoff, E;
Singh, K;
Mangu, CD;
Dawson, R;
Phillips, PP;
... Hoelscher, M; + view all
(2013)
Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment.
The Lancet Respiratory Medicine
, 1
(6)
pp. 462-470.
10.1016/ S2213-2600(13)70119- X.
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Horsburgh, CR;
Shea, KM;
Phillips, P;
LaValley, M;
(2013)
Randomized clinical trials to identify optimal antibiotic treatment duration.
Trials
, 14
, Article 88. 10.1186/1745-6215-14-88.
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Phillips, PP;
Fielding, K;
Nunn, AJ;
(2013)
An Evaluation of Culture Results during Treatment for Tuberculosis as Surrogate Endpoints for Treatment Failure and Relapse.
PLoS One
, 8
(5)
, Article e63840. 10.1371/journal.pone.0063840.
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2012
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Howard, R;
McShane, R;
Lindesay, J;
Ritchie, C;
Baldwin, A;
Barber, R;
Burns, A;
... Phillips, P; + view all
(2012)
Donepezil and memantine for moderate-to-severe Alzheimer's disease.
The New England Journal of Medicine
, 366
(10)
893 - 903.
10.1056/NEJMoa1106668.
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2011
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Phillips, PP;
Crook, A;
Nunn, AJ;
(2011)
The evolution of and challenges in defining the clinical endpoint in tuberculosis treatment trials with non-inferiority designs.
Trials
, 12 Sup
, Article A31. 10.1186/1745-6215-12-S1-A31.
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2009
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Jones, R;
Sheehan, B;
Phillips, P;
Juszczak, E;
Adams, J;
Baldwin, A;
Ballard, C;
... DOMINO-AD team; + view all
(2009)
DOMINO-AD protocol: donepezil and memantine in moderate to severe Alzheimer's disease - a multicentre RCT.
Trials
, 10
, Article 57. 10.1186/1745-6215-10-57.
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