Browse by UCL people
Group by: Type | Date
Number of items: 36.
Article
Aguzzi, Erika A;
Desai, Roshni A;
Yang, Zhiyuan;
Davies, Andrew L;
Mahad, Don;
Siow, Bernard;
Yenicelik, Ayse G;
... Smith, Kenneth J; + view all
(2025)
A cause and protective treatment for acute and progressive disability and grey matter atrophy.
Brain
10.1093/brain/awaf465.
(In press).
|
 |
|
Bei, F;
Smith, KJ;
(2012)
Axonal protection achieved by blockade of sodium/calcium exchange in a new model of ischemia in vivo.
Neuropharmacology
, 63
(3)
405 - 414.
10.1016/j.neuropharm.2012.04.019.
|
 |
|
Brown, R;
Benveniste, H;
Black, SE;
Charpak, S;
Dichgans, M;
Joutel, A;
Nedergaard, M;
... Wardlaw, JM; + view all
(2018)
Understanding the role of the perivascular space in cerebral small vessel disease.
Cardiovascular Research
10.1093/cvr/cvy113.
(In press).
|
|
Chisholm, KI;
Ida, KK;
Davies, AL;
Papkovsky, DB;
Singer, M;
Dyson, A;
Tachtsidis, I;
... Smith, KJ; + view all
(2016)
In Vivo Imaging of Flavoprotein Fluorescence During Hypoxia Reveals the Importance of Direct Arterial Oxygen Supply to Cerebral Cortex Tissue.
Advances in Experimental Medicine and Biology
, 876
pp. 233-239.
10.1007/978-1-4939-3023-4_29.
|
|
|
Chisholm, KI;
Ida, KK;
Davies, AL;
Tachtsidis, I;
Papkovsky, DB;
Dyson, A;
Singer, M;
... Smith, KJ; + view all
(2016)
Hypothermia protects brain mitochondrial function from hypoxemia in a murine model of sepsis.
Journal of Cerebral Blood Flow and Metabolism
, 36
(11)
1955 -1964.
10.1177/0271678X15606457.
|
|
Cunniffe, N;
Vuong, KA;
Ainslie, D;
Baker, D;
Beveridge, J;
Bickley, S;
Camilleri, P;
... Coles, A; + view all
(2020)
Systematic approach to selecting licensed drugs for repurposing in the treatment of progressive multiple sclerosis.
Journal of Neurology, Neurosurgery & Psychiatry
10.1136/jnnp-2020-324286.
(In press).
|
|
|
Desai, RA;
Davies, AL;
Del Rossi, N;
Tachrount, M;
Dyson, A;
Gustavson, B;
Kaynezhad, P;
... Smith, KJ; + view all
(2020)
Nimodipine reduces dysfunction and demyelination in models of multiple sclerosis.
Annals of Neurology
, 88
(1)
pp. 123-136.
10.1002/ana.25749.
|
|
|
Desai, RA;
Davies, AL;
Tachrount, M;
Kasti, M;
Laulund, F;
Golay, X;
Smith, KJ;
(2016)
Cause and prevention of demyelination in a model multiple sclerosis lesion.
Annals of Neurology
, 79
(4)
pp. 591-604.
10.1002/ana.24607.
|
|
Desai, RA;
Smith, KJ;
(2017)
Experimental autoimmune encephalomyelitis from a tissue energy perspective.
F1000Res
, 6
, Article 1973. 10.12688/f1000research.11839.1.
|
|
|
Evans, Phoebe G;
Sajic, Maria;
Yu, Yichao;
Harrison, Ian F;
Hosford, Patrick S;
Smith, Ken J;
Lythgoe, Mark F;
... Wells, Jack A; + view all
(2023)
Changes in cardiac-driven perivascular fluid movement around the MCA in a pharmacological model of acute hypertension detected with non-invasive MRI.
Journal of Cerebral Blood Flow & Metabolism
10.1177/0271678X231209641.
(In press).
|
|
|
Felts, PA;
Baker, TA;
Smith, KJ;
(1997)
Conduction in segmentally demyelinated mammalian central axons.
Journal of Neuroscience
, 17
(19)
7267 - 7277.
|
|
|
Frison, M;
Faccenda, D;
Abeti, R;
Rigon, M;
Strobbe, D;
England-Rendon, BS;
Cash, D;
... Campanella, M; + view all
(2021)
The translocator protein (TSPO) is prodromal to mitophagy loss in neurotoxicity.
Molecular Psychiatry
10.1038/s41380-021-01050-z.
(In press).
|
|
|
Giannoni, L;
Lange, F;
Davies, AL;
Dua, A;
Gustavson, B;
Smith, KJ;
Tachtsidis, I;
(2018)
Hyperspectral Imaging of the Hemodynamic and Metabolic States of the Exposed Cortex: Investigating a Commercial Snapshot Solution.
Advances in Experimental Medicine and Biology
, 1072
pp. 13-20.
10.1007/978-3-319-91287-5_3.
|
|
|
Giannoni, L;
Lange, F;
Sajic, M;
Smith, KJ;
Tachtsidis, I;
(2021)
A hyperspectral imaging system for mapping haemoglobin and cytochrome-c-oxidase concentration changes in the exposed cerebral cortex.
IEEE Journal of Selected Topics in Quantum Electronics
10.1109/JSTQE.2021.3053634.
(In press).
|
 |
|
Horsburgh, K;
Wardlaw, JM;
van Agtmael, T;
Allan, SM;
Ashford, MLJ;
Bath, PM;
Brown, R;
... Work, LM; + view all
(2018)
Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology.
Clinical Science
, 132
(8)
pp. 851-868.
10.1042/CS20171620.
|
|
Ida, KK;
Chisholm, KI;
Malbouisson, LMS;
Papkovsky, DB;
Dyson, A;
Singer, M;
Duchen, MR;
(2017)
Protection of cerebral microcirculation, mitochondrial function and electrocortical activity by small-volume resuscitation with terlipressin in a model of haemorrhagic shock.
British Journal of Anaesthesia
10.1016/j.bja.2017.11.074.
(In press).
|
|
|
Ida, KK;
Otsuki, DA;
Cotarelli Sasaki, AT;
Borges, ES;
Cardoso Castro, LU;
Sanches, TR;
Shimizu, M-HM;
... Malbouisson, L-MS; + view all
(2015)
Effects of terlipressin as early treatment for protection of brain in a model of haemorrhagic shock.
Critical Care
, 19
, Article 107. 10.1186/s13054-015-0825-9.
|
|
|
Licht-Mayer, Simon;
Campbell, Graham R;
Mehta, Arpan R;
McGill, Katie;
Symonds, Alex;
Al-Azki, Sarah;
Pryce, Gareth;
... Mahad, Don J; + view all
(2023)
Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis.
Neuropathology and Applied Neurobiology
, 49
(1)
, Article e12851. 10.1111/nan.12851.
|
|
Licht-Mayer, S;
Campbell, GR;
Canizares, M;
Mehta, AR;
Gane, AB;
McGill, K;
Ghosh, A;
... Mahad, DJ; + view all
(2020)
Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis.
Acta Neuropathologica
, 140
pp. 143-167.
10.1007/s00401-020-02179-x.
|
|
|
Martinez Sosa, S;
Smith, KJ;
(2017)
Understanding a role for hypoxia in lesion formation and location in the deep and periventricular white matter in small vessel disease and multiple sclerosis.
Clinical Science
, 131
(20)
pp. 2503-2524.
10.1042/CS20170981.
|
|
Matarin, M;
Perona, M;
Salih, DA;
Yasvoina, M;
Cummings, DM;
Liu, W;
NahabooSolim, MA;
... Smith, KJ; + view all
(2015)
A Genome-wide gene-expression analysis and database in transgenic mice during development of amyloid or tau pathology.
Cell Reports
, 10
(4)
633 - 645.
10.1016/j.celrep.2014.12.041.
|
|
|
Sadeghian, M;
Mastrolia, V;
Haddad, AR;
Mosley, A;
Mullali, G;
Schiza, D;
Sajic, M;
... Smith, KJ; + view all
(2016)
Mitochondrial dysfunction is an important cause of neurological deficits in an inflammatory model of multiple sclerosis.
Scientific Reports
, 6
, Article 33249. 10.1038/srep33249.
|
|
|
Sadeghian, M;
Mullali, G;
Pocock, JM;
Piers, T;
Roach, A;
Smith, KJ;
(2016)
Neuroprotection by safinamide in the 6-hydroxydopamine model of Parkinson's disease.
Neuropathology and Applied Neurobiology
, 42
(5)
pp. 423-435.
10.1111/nan.12263.
|
|
Sajic, M;
Rumora, AE;
Kanhai, AA;
Dentoni, G;
Varatharajah, S;
Casey, C;
Brown, RDR;
... Smith, KJ; + view all
(2021)
High dietary fat consumption impairs axonal mitochondrial function in vivo.
Journal of Neuroscience
, 41
(19)
pp. 4321-4334.
10.1523/JNEUROSCI.1852-20.2021.
|
|
Sajic, M;
Hunt, DP;
Lee, W;
Compston, DA;
Schweimer, JV;
Gregson, NA;
Chandran, S;
(2012)
Mesenchymal stem cells lack efficacy in the treatment of experimental autoimmune neuritis despite in vitro inhibition of T-cell proliferation.
PLoS One
, 7
(2)
, Article e30708. 10.1371/journal.pone.0030708.
|
|
|
Sajic, M;
Ida, KK;
Canning, R;
Gregson, NA;
Duchen, MR;
Smith, KJ;
(2018)
Mitochondrial damage and "plugging" of transport selectively in myelinated, small-diameter axons are major early events in peripheral neuroinflammation.
Journal of Neuroinflammation
, 15
, Article 61. 10.1186/s12974-018-1094-8.
|
|
|
Sajic, M;
Mastrolia, V;
Lee, CY;
Trigo, D;
Sadeghian, M;
Mosley, AJ;
Gregson, NA;
... Smith, KJ; + view all
(2013)
Impulse conduction increases mitochondrial transport in adult Mammalian peripheral nerves in vivo.
PLoS Biol
, 11
(12)
, Article e1001754. 10.1371/journal.pbio.1001754.
|
|
|
Schuh, C;
Wimmer, I;
Hametner, S;
Haider, L;
Van Dam, A-M;
Liblau, RS;
Smith, KJ;
... Lassmann, H; + view all
(2014)
Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models.
Acta Neuropathologica
, 128
(2)
pp. 247-266.
10.1007/s00401-014-1263-5.
|
|
|
Turlejski, T;
Humoud, I;
Desai, R;
Smith, KJ;
Marina, N;
(2016)
Immunohistochemical evidence of tissue hypoxia and astrogliosis in the rostral ventrolateral medulla of spontaneously hypertensive rats.
Brain Research
, 1650
pp. 178-183.
10.1016/j.brainres.2016.09.012.
|
|
van der Putten, MA;
MacKenzie, LE;
Davies, AL;
Fernandez-Ramos, J;
Desai, RA;
Smith, KJ;
Harvey, AR;
(2017)
A multispectral microscope for in vivo oximetry of rat dorsal spinal cord vasculature.
Physiological Measurement
, 38
(2)
pp. 205-218.
10.1088/1361-6579/aa5527.
|
|
Wardlow, J;
Benveniste, H;
Nedergaard, M;
Zlokovic, B;
Mestre, H;
Lee, H;
Doubal, F;
... Black, S; + view all
(2020)
Perivascular spaces in the brain: anatomy, physiology and pathology.
Nature Reviews Neurology
, 16
pp. 137-153.
10.1038/s41582-020-0312-z.
|
|
Williams, Thomas;
Lange, Frederic;
Smith, Kenneth J;
Tachtsidis, Ilias;
Chataway, Jeremy;
(2024)
Investigating cortical hypoxia in multiple sclerosis via time-domain near-infrared spectroscopy.
Annals of Clinical and Translational Neurology
10.1002/acn3.52150.
(In press).
|
|
Yang, Zhiyuan;
Lange, Frédéric;
Xia, Yiqing;
Chertavian, Casey;
Cabolis, Katerina;
Sajic, Marija;
Werring, David J;
... Smith, Kenneth J; + view all
(2024)
Nimodipine Protects Vascular and Cognitive Function in an Animal Model of Cerebral Small Vessel Disease.
Stroke
, 55
(7)
pp. 1914-1922.
10.1161/STROKEAHA.124.047154.
|
|
Yang, Zhiyuan;
Marcoci, Cristina;
Öztürk, Hatice Kübra;
Giama, Eleni;
Yenicelik, Ayse Gertrude;
Slanař, Ondřej;
Linington, Christopher;
... Smith, Kenneth J; + view all
(2024)
Tissue Hypoxia and Associated Innate Immune Factors in Experimental Autoimmune Optic Neuritis.
International Journal of Molecular Sciences
, 25
(5)
, Article 3077. 10.3390/ijms25053077.
|
Working / discussion paper
|
Joel, Z;
Izquierdo, P;
Liu, W;
Hall, C;
Roberts, M;
Yap, K;
Nick, A;
... Edwards, F; + view all
(2018)
A TauP301L mouse model of dementia; development of pathology, synaptic transmission, microglial response and cognition throughout life.
BioRxiv: Cold Spring Harbor, NY, USA.
|
|
Thesis
|
Smith, KJ;
(1979)
Impulse conduction during demyelination and remyelination in central and peripheral nerve fibres.
Doctoral thesis , UNSPECIFIED.
|
