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Number of items: 63.
A
Abu-Hanna, J;
Taanman, J-W;
Abraham, D;
Clapp, L;
(2018)
Impact of treprostinil on dynamin-related protein 1 (DRP1) and mitochondrial fragmentation in pulmonary arterial hypertension (PAH).
[Lecture].
Presented at: 28th International Congress of the European-Respiratory-Society (ERS), Paris, FRANCE.
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Ang, R;
Mastitskaya, S;
Hosford, PS;
Basalay, M;
Specterman, M;
Aziz, Q;
Li, Y;
... Gourine, AV; + view all
(2018)
Modulation of Cardiac Ventricular Excitability by GLP-1 (Glucagon-Like Peptide-1).
Circulation: Arrhythmia and Electrophysiology
, 11
(10)
, Article e006740. 10.1161/CIRCEP.118.006740.
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B
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Basalay, MV;
Davidson, SM;
Gourine, AV;
Yellon, DM;
(2018)
Neural mechanisms in remote ischaemic conditioning in the heart and brain: mechanistic and translational aspects.
Basic Res Cardiol
, 113
(4)
, Article 25. 10.1007/s00395-018-0684-z.
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Blauwendraat, C;
Kia, DA;
Pihlstrom, L;
Gan-Or, Z;
Lesage, S;
Gibbs, JR;
Ding, J;
... Wood, NW; + view all
(2018)
Insufficient evidence for pathogenicity of SNCA His50Gln (H50Q) in Parkinson's disease.
Neurobiology of Aging
, 64
159.e5-159.e8.
10.1016/j.neurobiolaging.2017.12.012.
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Blauwendraat, C;
Reed, X;
Kia, DA;
Gan-Or, Z;
Lesage, S;
Pihlstrøm, L;
Guerreiro, R;
... COURAGE-PD (Comprehensive Unbiased Risk Factor Assessment for Ge; + view all
(2018)
Frequency of Loss of Function Variants in LRRK2 in Parkinson Disease.
JAMA Neurology
10.1001/jamaneurol.2018.1885.
(In press).
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Bøtker, HE;
Hausenloy, D;
Andreadou, I;
Antonucci, S;
Boengler, K;
Davidson, SM;
Deshwal, S;
... Heusch, G; + view all
(2018)
Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection.
Basic Research in Cardiology
, 113
(5)
, Article 39. 10.1007/s00395-018-0696-8.
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Bulluck, H;
Chan, MHH;
Paradies, V;
Bryant, JA;
Hernández-Reséndiz, S;
Cabrera-Fuentes, HA;
Watson, TJ;
... Hausenloy, DJ; + view all
(2018)
Impact of Cardioprotective Therapies on the Edema-Based Area at Risk by CMR in Reperfused STEMI.
Journal of the American College of Cardiology
, 71
(24)
pp. 2856-2858.
10.1016/j.jacc.2018.04.016.
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Bulluck, H;
Chan, MHH;
Paradies, V;
Yellon, RL;
Ho, HH;
Chan, MY;
Chin, CWL;
... Hausenloy, DJ; + view all
(2018)
Incidence and predictors of left ventricular thrombus by cardiovascular magnetic resonance in acute ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention: a meta-analysis.
Journal of Cardiovascular Magnetic Resonance
, 20
(1)
, Article 72. 10.1186/s12968-018-0494-3.
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Bulluck, H;
Dharmakumar, R;
Arai, AE;
Berry, C;
Hausenloy, DJ;
(2018)
Cardiovascular Magnetic Resonance in Acute ST-Segment-Elevation Myocardial Infarction: Recent Advances, Controversies, and Future Directions.
Circulation
, 137
(18)
pp. 1949-1964.
10.1161/CIRCULATIONAHA.117.030693.
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Bulluck, H;
Hausenloy, DJ;
(2018)
Letter by Bulluck and Hausenloy Regarding Article, "Dynamic Edematous Response of the Human Heart to Myocardial Infarction: Implications for Assessing Myocardial Area at Risk and Salvage".
Circulation
, 137
(16)
pp. 1748-1749.
10.1161/CIRCULATIONAHA.117.030974.
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Bulluck, H;
Hausenloy, DJ;
(2018)
Modulating NAD+ metabolism to prevent acute kidney injury.
Nature Medicine
, 24
pp. 1306-1307.
10.1038/s41591-018-0181-9.
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Byrne, G;
Ahmad-Villiers, S;
Du, Z;
McGregor, C;
(2018)
B4GALNT2 and xenotransplantation: A newly appreciated xenogeneic antigen.
Xenotransplantation
, 25
(5)
, Article e12394. 10.1111/xen.12394.
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Byrne, GW;
(2018)
Does human leukocyte antigens sensitization matter for xenotransplantation?
Xenotransplantation
, 25
(3)
, Article e12411. 10.1111/xen.12411.
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C
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Chong, J;
Bulluck, H;
Yap, EP;
Ho, AF;
Boisvert, WA;
Hausenloy, DJ;
(2018)
Remote ischemic conditioning in ST-segment elevation myocardial infarction - an update.
Conditioning Medicine
, 1
(5)
pp. 13-22.
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Coats, CJ;
Heywood, WE;
Virasami, A;
Ashrafi, N;
Syrris, P;
dos Remedios, C;
Treibel, TA;
... Elliott, PM; + view all
(2018)
Proteomic Analysis of the Myocardium in Hypertrophic Obstructive Cardiomyopathy.
Circulation: Genomic and Precision Medicine
, 11
(12)
, Article e001974. 10.1161/CIRCGEN.117.001974.
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Collis, R;
Tsang, V;
Pantazis, A;
Tome-Esteban, M;
Elliott, PM;
McGregor, CGA;
(2018)
Individualized surgical strategies for left ventricular outflow tract obstruction in hypertrophic cardiomyopathy.
European Journal of Cardio-Thoracic Surgery
, 53
(6)
pp. 1237-1243.
10.1093/ejcts/ezx458.
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Collis, R;
Watkinson, O;
O'Mahony, C;
Guttmann, OP;
Pantazis, A;
Tome-Esteban, M;
Tsang, V;
... Elliott, PM; + view all
(2018)
Long-term outcomes for different surgical strategies to treat left ventricular outflow tract obstruction in hypertrophic cardiomyopathy.
European Journal of Heart Failure
, 20
(2)
pp. 398-405.
10.1002/ejhf.1038.
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Cunningham, KP;
Veale, E;
Abu-Hanna, J;
Clapp, LH;
Mathie, A;
(2018)
The Role of the K2P Channels TASK-1, TREK-1 and TREK-2 in the Use of Treprostinil Therapy in Pulmonary Arterial Hypertension.
Presented at: Experimental Biology 2018, San Diego (CA), USA.
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D
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Davidson, SM;
Arjun, S;
Basalay, MV;
Bell, RM;
Bromage, DI;
Bøtker, HE;
Carr, RD;
... Yellon, DM; + view all
(2018)
The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection-evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology.
Basic Research in Cardiology
, 113
(6)
, Article 43. 10.1007/s00395-018-0704-z.
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Davidson, SM;
Duchen, MR;
(2018)
Imaging Mitochondrial Calcium Fluxes with Fluorescent Probes and Single- or Two-Photon Confocal Microscopy.
Methods in Molecular Biology
, 1782
pp. 171-186.
10.1007/978-1-4939-7831-1_10.
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Davidson, SM;
Riquelme, JA;
Zheng, Y;
Vicencio, JM;
Lavandero, S;
Yellon, DM;
(2018)
Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioning.
Scientific Reports
, 8
, Article 15885. 10.1038/s41598-018-34357-z.
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Davidson, SM;
Yellon, DM;
(2018)
Cardioprotection - is no the answer? A renewed look at nitric oxide signalling in cardiomyocytes.
[Editorial comment].
Cardiovascular Research
, 114
(6)
pp. 773-775.
10.1093/cvr/cvy073.
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Davidson, SM;
Yellon, DM;
(2018)
Protection From Cardiac Ischemia-Reperfusion Injury by Epigenetic Regulation of NADPH Oxidase.
Circulation
, 138
(24)
pp. 2837-2840.
10.1161/CIRCULATIONAHA.118.036697.
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Davis, SPX;
Wisniewski, L;
Kumar, S;
Correia, T;
Arridge, SR;
Frankel, P;
McGinty, J;
(2018)
Slice-illuminated optical projection tomography.
Optics Letters
, 43
(22)
pp. 5555-5558.
10.1364/OL.43.005555.
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Denny, P;
Feuermann, M;
Hill, DP;
Lovering, RC;
Plun-Favreau, H;
Roncaglia, P;
(2018)
Exploring autophagy with Gene Ontology.
Autophagy
, 14
(3)
pp. 419-436.
10.1080/15548627.2017.1415189.
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Do Carmo, H;
Arjun, S;
Petrucci, O;
Yellon, DM;
Davidson, SM;
(2018)
The Caspase 1 Inhibitor VX-765 Protects the Isolated Rat Heart via the RISK Pathway.
Cardiovascular Drugs and Therapy
, 32
(2)
pp. 165-168.
10.1007/s10557-018-6781-2.
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F
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Ferrari, R;
Kia, DA;
Tomkins, JE;
Hardy, J;
Wood, NW;
Lovering, RC;
Lewis, PA;
(2018)
Stratification of candidate genes for Parkinson's disease using weighted protein-protein interaction network analysis.
BMC Genomics
, 19
, Article 452. 10.1186/s12864-018-4804-9.
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Franceschini, N;
Giambartolomei, C;
de Vries, PS;
Finan, C;
Bis, JC;
Huntley, RP;
Lovering, RC;
... O'Donnell, CJ; + view all
(2018)
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.
Nature Communications
, 9
, Article 5141. 10.1038/s41467-018-07340-5.
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H
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Hausenloy, D;
(2018)
The frail patient with heart disease: Please handle with care!
Heart and Metabolism
, 76
pp. 2-3.
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Hausenloy, DJ;
Bulluck, H;
(2018)
Risk Stratification by Cardiovascular Magnetic Resonance After Reperfused ST-Segment Elevation Myocardial Infarction: Ready for Prime Time?
JACC: Cardiovasc Imaging
, 11
(6)
pp. 826-828.
10.1016/j.jcmg.2017.05.025.
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Hausenloy, DJ;
Chilian, W;
Crea, F;
Davidson, SM;
Ferdinandy, P;
Garcia-Dorado, D;
van Royen, N;
... Heusch, G; + view all
(2018)
The coronary circulation in acute myocardial ischaemia/reperfusion injury - a target for cardioprotection.
Cardiovascular Research
10.1093/cvr/cvy286.
(In press).
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Hernandez-Resendiz, S;
Chinda, K;
Ong, S-B;
Cabrera-Fuentes, H;
Zazueta, C;
Hausenloy, DJ;
(2018)
The Role of Redox Dysregulation in the Inflammatory Response to Acute Myocardial Ischaemia-reperfusion Injury - Adding Fuel to the Fire.
[Review].
Current Medicinal Chemistry
, 25
(11)
pp. 1275-1293.
10.2174/0929867324666170329100619.
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Hoque, A;
Sivakumaran, P;
Bond, ST;
Ling, NXY;
Kong, AM;
Scott, JW;
Bandara, N;
... Lim, SY; + view all
(2018)
Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells.
Cell Death Discovery
, 4
, Article 39. 10.1038/s41420-018-0042-9.
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Huntley, RP;
Kramarz, B;
Sawford, T;
Umrao, Z;
Kalea, AZ;
Acquaah, V;
Martin, M-J;
... Lovering, RC; + view all
(2018)
Expanding the horizons of microRNA bioinformatics.
RNA
, 24
pp. 1005-1017.
10.1261/rna.065565.118.
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Hussain, A;
Ghosh, S;
Kalkhoran, SB;
Hausenloy, DJ;
Hanssen, E;
Rajagopal, V;
(2018)
An automated workflow for segmenting single adult cardiac cells from large-volume serial block-face scanning electron microscopy data.
Journal of Structural Biology
, 202
(3)
pp. 275-285.
10.1016/j.jsb.2018.02.005.
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I
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International Society for Biocuration;
(2018)
Biocuration: Distilling data into knowledge.
PLoS Biology
, 16
(4)
, Article e2002846. 10.1371/journal.pbio.2002846.
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K
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Kramarz, B;
Roncaglia, P;
Meldal, BHM;
Huntley, RP;
Martin, MJ;
Orchard, S;
Parkinson, H;
... Lovering, RC; + view all
(2018)
Improving the Gene Ontology Resource to Facilitate More Informative Analysis and Interpretation of Alzheimer's Disease Data.
Genes
, 9
(12)
, Article 593. 10.3390/genes9120593.
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L
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Li, N;
Zhang, Y;
Sidlauskas, K;
Ellis, M;
Evans, I;
Frankel, P;
Lau, J;
... Brandner, S; + view all
(2018)
Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades.
Oncogene
, 37
pp. 4313-4333.
10.1038/s41388-018-0277-1.
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Lim, VG;
Bell, RM;
Arjun, S;
Kolatsi-Joannou, MK;
Long, DA;
Yellon, D;
(2018)
SGLT2 inhibitor, Canagliflozin, attenuates myocardial infarction in the diabetic and non-diabetic heart.
JACC: Basic to Translational Science
10.1016/j.jacbts.2018.10.002.
(In press).
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Lovering, RC;
Roncaglia, P;
Howe, DG;
Laulederkind, SJF;
Khodiyar, VK;
Berardini, TZ;
Tweedie, S;
... Hill, DP; + view all
(2018)
Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology.
Circulation: Genomic and Precision Medicine
, 11
(2)
, Article e001813. 10.1161/CIRCGEN.117.001813.
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M
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Mahmoud, M;
Evans, I;
Wisniewski, L;
Frankel, P;
Zachary, I;
(2018)
A novel transgenic mouse model reveals an essential role for Bcar1/p130Cas in embryonic heart development and outflow tract septation.
Presented at: Frontiers in CardioVascular Biology 2018: Fifth Congress of the ESC Council on Basic Cardiovascular Science, Vienna, Austria.
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Maskell, LJ;
Mahadeo, AV;
Budhram-Mahadeo, VS;
(2018)
POU4F2/Brn-3b transcription factor is associated with survival and drug resistance in human ovarian cancer cells.
Oncotarget
, 9
(95)
pp. 36770-36779.
10.18632/oncotarget.26371.
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Maulik, A;
Davidson, SM;
Piotrowska, I;
Walker, M;
Yellon, DM;
(2018)
Ischaemic Preconditioning Protects Cardiomyocytes from Anthracycline-Induced Toxicity via the PI3K Pathway.
Cardiovascular Drugs and Therapy
, 32
(3)
pp. 245-253.
10.1007/s10557-018-6793-y.
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McGregor, CGA;
Takeuchi, Y;
Scobie, L;
Byrne, G;
(2018)
Pervading Strategies and Infectious Risk for Clinical Xenotransplantation.
Xenotransplantation
, 25
(4)
, Article e12402. 10.1111/xen.12402.
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Monypenny, J;
Milewicz, H;
Flores-Borja, F;
Weitsman, G;
Cheung, A;
Chowdhury, R;
Burgoyne, T;
... Ng, T; + view all
(2018)
ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation.
Cell Reports
, 24
(3)
pp. 630-641.
10.1016/j.celrep.2018.06.066.
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Mota, F;
Fotinou, C;
Rhana, R;
Edith Chan, AW;
Yelland, T;
Arooz, MT;
O'Leary, AP;
... Djordjevic, S; + view all
(2018)
Architecture and Hydration of the Arginine Binding Site of Neuropilin-1.
The FEBS Journal
, 285
(7)
pp. 1290-1304.
10.1111/febs.14405.
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N
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Nie, S;
Wang, X;
Sivakumaran, P;
Chong, MMW;
Liu, X;
Karnezis, T;
Bandara, N;
... Lim, SY; + view all
(2018)
Biologically active constituents of the secretome of human W8B2(+) cardiac stem cells.
SWcientific Reports
, 8
, Article 1579. 10.1038/s41598-018-19855-4.
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O
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Ong, S-B;
Hernández-Reséndiz, S;
Crespo-Avilan, GE;
Mukhametshina, RT;
Kwek, X-Y;
Cabrera-Fuentes, HA;
Hausenloy, DJ;
(2018)
Inflammation following acute myocardial infarction: Multiple players, dynamic roles, and novel therapeutic opportunities.
Pharmacology & Therapeutics
, 186
pp. 73-87.
10.1016/j.pharmthera.2018.01.001.
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Ong, S-B;
Katwadi, K;
Kwek, X-Y;
Ismail, NI;
Chinda, K;
Ong, S-G;
Hausenloy, DJ;
(2018)
Non-coding RNAs as therapeutic targets for preventing myocardial ischemia-reperfusion injury.
Expert Opinion on Therapeutic Targets
, 22
(3)
pp. 247-261.
10.1080/14728222.2018.1439015.
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P
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Patel, JA;
Shen, L;
Hall, SM;
Benyahia, C;
Norel, X;
McAnulty, RJ;
Moledina, S;
... Clapp, LH; + view all
(2018)
Prostanoid EP₂ Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells.
International Journal of Molecular Sciences
, 19
(8)
, Article 2372. 10.3390/ijms19082372.
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Powell, J;
Mota, F;
Steadman, D;
Soudy, C;
Miyauchi, JT;
Crosby, S;
Jarvis, A;
... Selwood, DL; + view all
(2018)
Small molecule neuropilin-1 antagonists combine anti-angiogenic and anti-tumour activity with immune modulation through reduction of transforming growth factor beta (TGFβ) production in regulatory T-cells.
Journal of Medicinal Chemistry
, 61
(9)
pp. 4135-4154.
10.1021/acs.jmedchem.8b00210.
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Preston, IR;
Shen, L;
Patel, J;
Sood, N;
Torres, F;
Cadaret, L;
Adams, J;
(2018)
Ralinepag Reduces Pulmonary Vascular Resistance (PVR) in a Phase 2 Study Confirming Preclinical Findings on Prostacyclin (IP) Receptors in Human Tissues.
Presented at: Chest Annual Meeting 2018, San Antonio, TX, USA.
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R
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Ramachandra, CJA;
Mehta, A;
Wong, P;
Ja, KPMM;
Fritsche-Danielson, R;
Bhat, RV;
Hausenloy, DJ;
... Shim, W; + view all
(2018)
Fatty acid metabolism driven mitochondrial bioenergetics promotes advanced developmental phenotypes in human induced pluripotent stem cell derived cardiomyocytes.
International Journal of Cardiology
, 272
pp. 288-297.
10.1016/j.ijcard.2018.08.069.
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Rossello, X;
He, Z;
Yellon, DM;
(2018)
Myocardial Infarct Size Reduction Provided by Local and Remote Ischaemic Preconditioning: References Values from the Hatter Cardiovascular Institute.
Cardiovascular Drugs and Therapy
, 32
(2)
pp. 127-133.
10.1007/s10557-018-6788-8.
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Rossello, X;
Riquelme, JA;
Davidson, SM;
Yellon, DM;
(2018)
Role of PI3K in myocardial ischaemic preconditioning: mapping pro-survival cascades at the trigger phase and at reperfusion.
Journal of Cellular and Molecular Medicine
, 22
(2)
pp. 926-935.
10.1111/jcmm.13394.
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Rossello, X;
Yellon, DM;
(2018)
The RISK pathway and beyond.
Basic Research in Cardiology
, 113
(1)
, Article 2. 10.1007/s00395-017-0662-x.
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S
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Samangouei, P;
Crespo-Avilan, GE;
Cabrera-Fuentes, H;
Hernández-Reséndiz, S;
Ismail, NI;
Katwadi, KB;
Boisvert, WA;
(2018)
MiD49 and MiD51: New mediators of mitochondrial fission and novel targets for cardioprotection.
Conditioning Medicine
, 1
(5)
pp. 239-246.
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Samangouei, Parisa;
(2018)
Investigating the role of mitochondrial dynamic proteins MiD49 and MiD51, as novel targets of cardioprotection.
Doctoral thesis (Ph.D), UCL (University College London).
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Sezer, M;
Van Royen, N;
Umman, B;
Bugra, Z;
Bulluck, H;
Hausenloy, DJ;
Umman, S;
(2018)
Coronary microvascular injury in reperfused acute myocardial infarction: A view from an integrative perspective.
Journal of the American Heart Association
, 7
(21)
, Article e009949. 10.1161/JAHA.118.009949.
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Sivade Dumousseau, M;
Alonso-López, D;
Ammari, M;
Bradley, G;
Campbell, NH;
Ceol, A;
Cesareni, G;
... Orchard, S; + view all
(2018)
Encompassing new use cases - level 3.0 of the HUPO-PSI format for molecular interactions.
BMC Bioinformatics
, 19
, Article 134. 10.1186/s12859-018-2118-1.
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W
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Wilder, CDE;
Pavlaki, N;
Dursun, T;
Gyimah, P;
Caldwell-Dunn, E;
Ranieri, A;
Lewis, HR;
(2018)
Facilitation of ischaemia‐induced ventricular fibrillation by catecholamines is mediated by β1 and β2 agonism in the rat heart in vitro.
British Journal of Pharmacology
, 175
(10)
pp. 1669-1690.
10.1111/bph.14176.
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Winter, J;
Bishop, MJ;
Wilder, CDE;
O'Shea, C;
Pavlovic, D;
Shattock, MJ;
(2018)
Sympathetic nervous regulation of calcium and action potential alternans in the intact heart.
Frontiers in Physiology
, 9
, Article 16. 10.3389/fphys.2018.00016.
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Y
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Yellon, DM;
He, Z;
Khambata, R;
Ahluwalia, A;
Davidson, SM;
(2018)
The GTN patch: a simple and effective new approach to cardioprotection?
Basic Research in Cardiology
, 113
(3)
p. 20.
10.1007/s00395-018-0681-2.
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