UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Browse by UCL Departments and Centres

Group by: Author | Type
Jump to: Article | Thesis
Number of items: 48.

Article

Bartlett, RD; Burley, S; Ip, M; Phillips, JB; Choi, D; (2020) Cell Therapies for Spinal Cord Injury: Trends and Challenges of Current Clinical Trials. Neurosurgery , 87 (4) E456-E472. 10.1093/neuros/nyaa149. Green open access
file

Bartlett, RD; Eleftheriadou, D; Evans, R; Choi, D; Phillips, JB; (2020) Mechanical properties of the spinal cord and brain: Comparison with clinical-grade biomaterials for tissue engineering and regenerative medicine. Biomaterials , 258 , Article 120303. 10.1016/j.biomaterials.2020.120303. Green open access
file

Beilina, A; Bonet-Ponce, L; Kumaran, R; Kordich, JJ; Ishida, M; Mamais, A; Kaganovich, A; ... Cookson, MR; + view all (2020) The Parkinson’s disease protein LRRK2 interacts with the GARP complex to promote retrograde transport to the trans-Golgi network. Cell Reports , 31 (5) , Article 107614. 10.1016/j.celrep.2020.107614. Green open access
file

Carrara, L; Magni, P; Teutonico, D; Pasotti, L; Pasqua, OD; Kloprogge, F; (2020) Ethambutol disposition in humans: challenges and limitations of whole-body physiologically-based pharmacokinetic modelling in early drug development. European Journal of Pharmaceutical Sciences , 150 , Article 105359. 10.1016/j.ejps.2020.105359. Green open access
file

Choompoo, N; Bartley, OJM; Precious, SV; Vinh, NN; Schnell, C; Garcia, A; Roberton, VH; ... Rosser, AE; + view all (2020) Induced pluripotent stem cells derived from the developing striatum as a potential donor source for cell replacement therapy for Huntington disease. Cytotherapy 10.1016/j.jcyt.2020.06.001. (In press). Green open access
file

Costa, B; Manzoni, C; Bernal-Quiros, M; Kia, D; Aguilar, M; Alvarez, I; Alvarez, V; ... Hardy, J; + view all (2020) C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts. Neurology , 95 (24) e3288-e3302. 10.1212/WNL.0000000000010914. Green open access
file

Coy, R; Al-Badri, G; Kayal, C; O'Rourke, C; Kingham, PJ; Phillips, JB; Shipley, RJ; (2020) Combining in silico and in vitro models to inform cell seeding strategies in tissue engineering. Journal of the Royal Society Interface , 17 (164) , Article 20190801. 10.1098/rsif.2019.0801. Green open access
file

D'Agate, S; Chavan, C; Manyak, M; Palacios-Moreno, JM; Oelke, M; Michel, MC; Roehrborn, CG; (2020) Impact of early vs. delayed initiation of dutasteride/tamsulosin combination therapy on the risk of acute urinary retention or BPH-related surgery in LUTS/BPH patients with moderate-to-severe symptoms at risk of disease progression. World Journal of Urology 10.1007/s00345-020-03517-0. (In press). Green open access
file

D'Agate, S; Wilson, T; Adalig, B; Manyak, M; Palacios-Moreno, JM; Chavan, C; Oelke, M; ... Della Pasqua, O; + view all (2020) Impact of disease progression on individual IPSS trajectories and consequences of immediate versus delayed start of treatment in patients with moderate or severe LUTS associated with BPH. World Journal of Urology , 38 pp. 463-472. 10.1007/s00345-019-02783-x. Green open access
file

D'Agate, S; Wilson, T; Adalig, B; Manyak, M; Palacios-Moreno, JM; Chavan, C; Oelke, M; ... Della Pasqua, O; + view all (2020) Model-based meta-analysis of individual IPSS trajectories in patients with benign prostatic hyperplasia with moderate or severe symptoms. British Journal of Clinical Pharmacology , 86 (8) pp. 1585-1599. 10.1111/bcp.14268. Green open access
file

D’Agate, S; Musuamba Tshinanu, F; Della Pasqua, O; (2020) Dose rationale for amoxicillin in neonatal sepsis when referral is not possible. Frontiers in Pharmacology , 11 , Article 521933. 10.3389/fphar.2020.521933. Green open access
file

Ecker, A; Romani, A; Sáray, S; Káli, S; Migliore, M; Falck, J; Lange, S; ... Ramaswamy, S; + view all (2020) Data-driven integration of hippocampal CA1 synaptic physiology in silico. Hippocampus 10.1002/hipo.23220. (In press). Green open access
file

Hague, JP; Mieczkowski, PW; O'Rourke, C; Loughlin, AJ; Phillips, JB; (2020) Microscopic biophysical model of self-organization in tissue due to feedback between cell- and macroscopic-scale forces. Physical Review Research , 2 (4) , Article 043217. 10.1103/physrevresearch.2.043217. Green open access
file

Harvey, K; (2020) Sequential screening nominates the Parkinson’s disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis. Neurobiology of Disease 10.1016/j.nbd.2020.104948. Green open access
filefile

Horrigan, J; Gomes, TB; Snape, M; Nikolenko, N; McMorn, A; Evans, S; Yaroshinsky, A; ... Lochmüller, H; + view all (2020) A Phase 2 Study of AMO-02 (tideglusib) in Congenital and Childhood Onset Myotonic Dystrophy Type 1 (DM1). Pediatric Neurology 10.1016/j.pediatrneurol.2020.08.001. (In press). Green open access
file

Huang, Z; Powell, R; Phillips, JB; Haastert-Talini, K; (2020) Perspective on Schwann Cells Derived from Induced Pluripotent Stem Cells in Peripheral Nerve Tissue Engineering. Cells , 9 (11) , Article 2497. 10.3390/cells9112497. Green open access
file

Karda, R; Rahim, AA; Wong, AMS; Suff, N; Diaz, JA; Perocheau, DP; Tijani, M; ... Waddington, SN; + view all (2020) Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors. Scientific Reports , 10 (1) , Article 2121. 10.1038/s41598-020-59075-3. Green open access
file

Kayal, C; Moeendarbary, E; Shipley, R; Phillips, J; (2020) Mechanical response of neural cells to physiologically relevant stiffness gradients. Advanced Healthcare Materials , 9 (8) , Article 1901036. 10.1002/adhm.201901036. Green open access
file

Kozdon, K; Caridi, B; Duru, I; Ezra, DG; Phillips, JB; Bailly, M; (2020) A Tenon's capsule/bulbar conjunctiva interface biomimetic to model fibrosis and local drug delivery. PLoS One , 15 (11) , Article e0241569. 10.1371/journal.pone.0241569. Green open access
file

Krishnaswami, S; Austin, D; Della Pasqua, O; Gastonguay, MR; Gobburu, J; Van der Graaf, PH; Ouellet, D; ... Visser, SAG; + view all (2020) MID3: Mission Impossible or Model-Informed Drug Discovery and Development? Point-Counterpoint Discussions on Key Challenges. Clinical Pharmacology & Therapeutics 10.1002/cpt.1788. Green open access
file

Leo, A; Nesci, V; Tallarico, M; Amodio, N; Gallo Cantafio, EM; De Sarro, G; Constanti, A; ... Citraro, R; + view all (2020) IL-6 Receptor Blockade by Tocilizumab Has Anti-absence and Anti-epileptogenic Effects in the WAG/Rij Rat Model of Absence Epilepsy. Neurotherapeutics , 17 pp. 2004-2014. 10.1007/s13311-020-00893-8. Green open access
file

Liu, W; Kleine-Holthaus, S-M; Herranz-Martin, S; Aristorena, M; Mole, SE; Smith, AJ; Ali, RR; (2020) Experimental gene therapies for the NCLs. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease , 1866 (9) , Article 165772. 10.1016/j.bbadis.2020.165772. Green open access
file

Liu, W; Taso, O; Wang, R; Bayram, S; Graham, AC; Garcia-Reitboeck, P; Mallach, A; ... Salih, DA; + view all (2020) Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions. Human Molecular Genetics 10.1093/hmg/ddaa209. (In press). Green open access
file

Maggio, A; Kattamis, A; Felisi, M; Reggiardo, G; El-Beshlawy, A; Bejaoui, M; Sherief, L; ... Ceci, A; + view all (2020) Evaluation of the effectiveness and safety of deferiprone compared to deferasirox in pediatric patients with transfusion-dependent hemoglobinopathies (DEEP-2): a multicenter, randomized, open label, non-inferiority, phase-III trial. The Lancet Haematology , 7 (6) e469-e478. 10.1016/S2352-3026(20)30100-9. Green open access
file

Massaro, G; Hughes, MP; Whaler, SM; Wallom, K-L; Priestman, DA; Platt, FM; Waddington, SN; (2020) Systemic AAV9 gene therapy using the synapsin I promoter rescues a mouse model of neuronopathic Gaucher disease but with limited cross-correction potential to astrocytes. Human Molecular Genetics 10.1093/hmg/ddz317. (In press). Green open access
file

Mencacci, NE; Reynolds, R; Ruiz, SG; Vandrovcova, J; Forabosco, P; Sánchez-Ferrer, A; Volpato, V; ... Ryten, M; + view all (2020) Dystonia genes functionally converge in specific neurons and share neurobiology with psychiatric disorders. Brain , Article awaa217. 10.1093/brain/awaa217. (In press). Green open access
file

Muangsanit, P; Day, A; Dimiou, S; Ataç, AF; Kayal, C; Park, H; Nazhat, SN; (2020) Rapidly formed stable and aligned dense collagen gels seeded with Schwann cells support peripheral nerve regeneration. Journal of Neural Engineering 10.1088/1741-2552/abaa9c. (In press). Green open access
file

Muliaditan, M; Della Pasqua, O; (2020) Evaluation of pharmacokinetic‐pharmacodynamic relationships and selection of drug combinations for tuberculosis. British Journal of Clinical Pharmacology 10.1111/bcp.14371. (In press). Green open access
file

Nelvagal, HR; Hurtado, ML; Eaton, SL; Kline, RA; Lamont, DJ; Sands, MS; Wishart, TM; (2020) Comparative proteomic profiling reveals mechanisms for early spinal cord vulnerability in CLN1 disease. Scientific Reports , 10 (1) , Article 15157. 10.1038/s41598-020-72075-7. Green open access
file

Nesci, V; Russo, E; Arcidiacono, B; Citraro, R; Tallarico, M; Constanti, A; Brunetti, A; ... Leo, A; + view all (2020) Metabolic Alterations Predispose to Seizure Development in High-Fat Diet-Treated Mice: the Role of Metformin. Molecular Neurobiology , 57 pp. 4778-4789. 10.1007/s12035-020-02062-6. Green open access
file

Petrache, AL; Khan, AA; Nicholson, MW; Monaco, A; Kuta-Siejkowska, M; Haider, S; Hilton, S; ... Ali, A; + view all (2020) Selective Modulation of α5 GABAA Receptors Exacerbates Aberrant Inhibition at Key Hippocampal Neuronal Circuits in APP Mouse Model of Alzheimer’s Disease. Frontiers in Cellular Neuroscience , 14 , Article 568194. 10.3389/fncel.2020.568194. Green open access
file

Plotegher, N; Perocheau, D; Ferrazza, R; Massaro, G; Bhosale, G; Zambon, F; Rahim, AA; ... Duchen, MR; + view all (2020) Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload. Cell Death & Differentiation , 27 pp. 1588-1603. 10.1038/s41418-019-0442-2. Green open access
file

Poupon-Bejuit, L; Rocha-Ferreira, E; Thornton, C; Hagberg, H; Rahim, AA; (2020) Neuroprotective Effects of Diabetes Drugs for the Treatment of Neonatal Hypoxia-Ischemia Encephalopathy. Frontiers in Cellular Neuroscience , 14 , Article 112. 10.3389/fncel.2020.00112. Green open access
file

Rahim, AA; Gissen, P; (2020) Gene therapy for global brain diseases: one small step for mice, one giant leap for humans. Brain , 143 (7) pp. 1964-1966. 10.1093/brain/awaa189. Green open access
file

Rahim, AA; Russell, C; Mole, SE; (2020) Special edition: The NCLs/Batten disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease , 1866 (9) , Article 165824. 10.1016/j.bbadis.2020.165824. Green open access
file

Rayner, MLD; Brown, HL; Wilcox, M; Phillips, JB; Quick, TJ; (2020) Quantifying regeneration in patients following peripheral nerve injury. Journal of Plastic, Reconstructive & Aesthetic Surgery , 73 (2) pp. 201-208. 10.1016/j.bjps.2019.10.007. Green open access
file

Rayner, MLD; Grillo, A; Williams, G; Tawfik, E; Zhang, T; Volitaki, C; Craig, DQM; ... Phillips, J; + view all (2020) Controlled local release of PPARγ agonists from biomaterials to treat peripheral nerve injury. Journal of Neural Engineering 10.1088/1741-2552/aba7cc. (In press). Green open access
file

Sancandi, M; Uysal-Onganer, P; Kraev, I; Mercer, A; Lange, S; (2020) Protein Deimination Signatures in Plasma and Plasma-EVs and Protein Deimination in the Brain Vasculature in a Rat Model of Pre-Motor Parkinson’s Disease. International Journal of Molecular Sciences , 21 (8) , Article 2743. 10.3390/ijms21082743. Green open access
file

Santoro, B; Shah, MM; (2020) Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels as Drug Targets for Neurological Disorders. Annual Review of Pharmacology and Toxicology , 60 pp. 109-131. 10.1146/annurev-pharmtox-010919-023356.

Seker Yilmaz, B; Baruteau, J; Rahim, AA; Gissen, P; (2020) Clinical and Molecular Features of Early Infantile Niemann Pick Type C Disease. International Journal of Molecular Sciences , 21 (14) , Article 5059. 10.3390/ijms21145059. Green open access
file

Shi, A; Petrache, AL; Shi, J; Ali, A; (2020) Preserved Calretinin interneurons in an app model of Alzheimer’s Disease disrupts hippocampal inhibition via up-regulated P2Y1 purinoreceptors. Cerebral Cortex , 30 (3) pp. 1272-1290. 10.1093/cercor/bhz165. Green open access
file

Skoura, N; Wang-Jaira, J; Della Pasqua, O; Chandrasekaran, V; Billiard, J; Yeakey, A; Smith, W; ... Tan, LK; + view all (2020) The effect of raxibacumab on the immunogenicity of anthrax vaccine adsorbed: a Phase IV, randomised, open-label, parallel-group, non-inferiority study. The Lancet Infectious Diseases , 20 (8) pp. 983-991. 10.1016/S1473-3099(20)30069-4. Green open access
filefilefile

Tomkins, J; Ferrari, R; Vavouraki, N; Hardy, J; Lovering, R; Lewis, P; McGuffin, L; (2020) PINOT: An Intuitive Resource for Integrating Protein-Protein Interactions. Cell Communication and Signaling , 18 , Article 92. 10.1186/s12964-020-00554-5. Green open access
file

van der Spek, SJF; Koopmans, F; Paliukhovich, I; Ramsden, SL; Harvey, K; Harvey, RJ; Smit, AB; (2020) Glycine Receptor Complex Analysis Using Immunoprecipitation-Blue Native Gel Electrophoresis-Mass Spectrometry. Proteomics 10.1002/pmic.201900403. (In press). Green open access
file

Wilcox, M; Gregory, H; Powell, R; Quick, TJ; Phillips, JB; (2020) Strategies for Peripheral Nerve Repair. Current Tissue Microenvironment Reports , 1 (2) pp. 49-59. 10.1007/s43152-020-00002-z. Green open access
file

Wilcox, MB; Laranjeira, SG; Eriksson, TM; Jessen, KR; Mirsky, R; Quick, TJ; Phillips, JB; (2020) Characterising cellular and molecular features of human peripheral nerve degeneration. Acta Neuropathologica Communications , 8 , Article 51. 10.1186/s40478-020-00921-w. Green open access
file

Zhang, D; Guelfi, S; Garcia-Ruiz, S; Costa, B; Reynolds, RH; D’Sa, K; Liu, W; ... Ryten, M; + view all (2020) Incomplete annotation has a disproportionate impact on our understanding of Mendelian and complex neurogenetic disorders. Science Advances , 6 (24) , Article eaay8299. 10.1126/sciadv.aay8299. Green open access
file

Thesis

Sabin, Antony James; (2020) A Quantitative Process for Enhancing End of Phase 2 Drug Development Decisions. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

This list was generated on Mon Nov 28 01:51:30 2022 GMT.