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Number of items: 55.
Article
Allmendinger, R;
Simaria, AS;
Turner, R;
Farid, SS;
(2014)
Closed-loop optimization of chromatography column sizing strategies in biopharmaceutical manufacture.
J Chem Technol Biotechnol
, 89
(10)
1481 - 1490.
10.1002/jctb.4267.
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Betts, JPJ;
Warr, SRC;
Finka, GB;
Uden, M;
Town, M;
Janda, JM;
Baganz, F;
(2014)
Impact of aeration strategies on fed-batch cell culture kinetics in a single-use 24-well miniature bioreactor.
BIOCHEMICAL ENGINEERING JOURNAL
, 82
105 - 116.
10.1016/j.bej.2013.11.010.
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Borg, Y;
Ullner, E;
Alagha, A;
Alsaedi, A;
Nesbeth, D;
Zaikin, A;
(2014)
Complex and unexpected dynamics in simple genetic regulatory networks.
INTERNATIONAL JOURNAL OF MODERN PHYSICS B
, 28
(14)
, Article ARTN 1430006. 10.1142/S0217979214300060.
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Chatel, A;
Kumpalume, P;
Hoare, M;
(2014)
Ultra Scale-Down Characterization of the Impact of Conditioning Methods for Harvested Cell Broths on Clarification by Continuous Centrifugation-Recovery of Domain Antibodies from rec E. coli.
BIOTECHNOLOGY AND BIOENGINEERING
, 111
(5)
913 - 924.
10.1002/bit.25164.
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Close, EJ;
Salm, JR;
Bracewell, DG;
Sorensen, E;
(2014)
A model based approach for identifying robust operating conditions for industrial chromatography with process variability.
CHEMICAL ENGINEERING SCIENCE
, 116
284 - 295.
10.1016/j.ces.2014.03.010.
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Close, EJ;
Salm, JR;
Bracewell, DG;
Sorensen, E;
(2014)
Modelling of industrial biopharmaceutical multicomponent chromatography.
CHEMICAL ENGINEERING RESEARCH & DESIGN
, 92
(7)
1304 - 1314.
10.1016/j.cherd.2013.10.022.
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Du, CJ;
Rios-Solis, L;
Ward, JM;
Dalby, PA;
Lye, GJ;
(2014)
Evaluation of CV2025 ω-transaminase for the bioconversion of lignin breakdown products into value-added chemicals: synthesis of vanillylamine from vanillin.
Biocatalysis and Biotransformation
, 32
(5-6)
pp. 302-313.
10.3109/10242422.2014.976632.
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Espuny Garcia Del Real, G;
Davies, J;
Bracewell, DG;
(2014)
Scale-down characterization of post-centrifuge flocculation processes for high-throughput process development.
Biotechnol Bioeng
, 111
(12)
2486 - 2498.
10.1002/bit.25313.
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Farid, SS;
Thompson, B;
Davidson, A;
(2014)
Continuous bioprocessing: the real thing this time? 10(th) Annual bioProcessUK Conference, December 3-4, 2013, London, UK.
MAbs
, 6
(6)
1357 - 1361.
10.4161/mabs.36151.
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Grant, C;
Deszcz, D;
Wei, YC;
Martínez-Torres, RJ;
Morris, P;
Folliard, T;
Sreenivasan, R;
... Baganz, F; + view all
(2014)
Identification and use of an alkane transporter plug-in for applications in biocatalysis and whole-cell biosensing of alkanes.
Sci Rep
, 4
, Article 5844. 10.1038/srep05844.
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Halim, Murni;
Rios-Solis, Leonardo;
Micheletti, Martina;
Ward, John M;
Lye, Gary J;
(2014)
Microscale methods to rapidly evaluate bioprocess options for increasing bioconversion yields: application to the ω-transaminase synthesis of chiral amines.
Bioprocess and Biosystems Engineering
, 37
(5)
pp. 931-941.
10.1007/s00449-013-1065-5.
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Hassan, S;
Keshavarz-Moore, E;
Ma, J;
Thomas, C;
(2014)
Breakage of transgenic tobacco roots for monoclonal antibody release in an ultra-scale down shearing device.
Biotechnology and Bioengineering
, 111
(1)
pp. 196-201.
10.1002/bit.25006.
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Hassan, S;
Keshavarz-Moore, E;
Ma, J;
Thomas, C;
(2014)
Breakage of transgenic tobacco roots for monoclonal antibody release in an ultra-scale down shearing device.
Biotechnology and Bioengineering
, 111
(1)
196 - 201.
10.1002/bit.25006.
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Herschy, B;
Whicher, A;
Camprubi, E;
Watson, C;
Dartnell, L;
Ward, J;
Evans, JR;
(2014)
An origin-of-life reactor to simulate alkaline hydrothermal vents.
J Mol Evol
, 79
(5-6)
213 - 227.
10.1007/s00239-014-9658-4.
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Hull, EA;
Livanos, M;
Miranda, E;
Smith, ME;
Chester, KA;
Baker, JR;
(2014)
Homogeneous Bispecifics by Disulfide Bridging.
Bioconjug Chem
, 25
(8)
pp. 1395-1401.
10.1021/bc5002467.
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Jaccard, N;
Griffin, LD;
Keser, A;
Macown, RJ;
Super, A;
Veraitch, FS;
Szita, N;
(2014)
Automated method for the rapid and precise estimation of adherent cell culture characteristics from phase contrast microscopy images.
Biotechnology and Bioengineering
, 111
(3)
pp. 504-517.
10.1002/bit.25115.
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Jaccard, N;
Macown, RJ;
Super, A;
Griffin, LD;
Veraitch, FS;
Szita, N;
(2014)
Automated and online characterization of adherent cell culture growth in a microfabricated bioreactor.
J Lab Autom
, 19
(5)
437 - 443.
10.1177/2211068214529288.
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Lichman, BR;
Lamming, ED;
Pesnot, T;
Smith, JM;
Hailes, HC;
Ward, JM;
(2014)
One-pot triangular chemoenzymatic cascades for the syntheses of chiral alkaloids from dopamine.
Green Chemistry
, 17
(2)
pp. 852-855.
10.1039/c4gc02325k.
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Liu, S;
Papageorgiou, LG;
Simaria, AS;
Farid, SS;
(2014)
Optimising chromatography strategies of antibody purification processes by mixed integer fractional programming techniques.
Computers and Chemical Engineering
, 68
151 - 164.
10.1016/j.compchemeng.2014.05.005.
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Macown, RJ;
Veraitch, FS;
Szita, N;
(2014)
Robust, microfabricated culture devices with improved control over the soluble microenvironment for the culture of embryonic stem cells.
Biotechnol J
, 9
(6)
pp. 805-813.
10.1002/biot.201300245.
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McDonnell, T;
Ioannou, Y;
Rahman, A;
(2014)
PEGylated drugs in rheumatology--why develop them and do they work?
Rheumatology
, 53
(3)
pp. 391-396.
10.1093/rheumatology/ket278.
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Odeleye, AO;
Marsh, DT;
Osborne, MD;
Lye, GJ;
Micheletti, M;
(2014)
On the fluid dynamics of a laboratory scale single-use stirred bioreactor.
Chem Eng Sci
, 111
(100)
299 - 312.
10.1016/j.ces.2014.02.032.
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Ojo, EO;
Auta, H;
Baganz, F;
Lye, GJ;
(2014)
Engineering characterisation of a shaken, single-use photobioreactor for early stage microalgae cultivation using Chlorella sorokiniana.
Bioresour Technol
, 173
367 - 375.
10.1016/j.biortech.2014.09.060.
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Rayner, LE;
Hui, GK;
Gor, J;
Heenan, RK;
Dalby, PA;
Perkins, SJ;
(2014)
The Fab conformations in the solution structure of human IgG4 restricts access to its Fc region: implications for functional activity.
J Biol Chem
, 289
(30)
pp. 20740-20756.
10.1074/jbc.M114.572404.
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Richter, N;
Simon, RC;
Kroutil, W;
Ward, JM;
Hailes, HC;
(2014)
Synthesis of pharmaceutically relevant 17-α-amino steroids using an ω-transaminase.
Chem Commun (Camb)
, 50
pp. 6098-6100.
10.1039/c3cc49080g.
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Rodriguez, G;
Anderlei, T;
Micheletti, M;
Yianneskis, M;
Ducci, A;
(2014)
On the measurement and scaling of mixing time in orbitally shaken bioreactors.
Biochemical Engineering Journal
, 82
pp. 10-21.
10.1016/j.bej.2013.10.021.
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Sayer, C;
Martinez-Torres, RJ;
Richter, N;
Isupov, MN;
Hailes, HC;
Littlechild, JA;
Ward, JM;
(2014)
The substrate specificity, enantioselectivity and structure of the (R)-selective amine : pyruvate transaminase from Nectria haematococca.
FEBS JOURNAL
, 281
(9)
2240 - 2253.
10.1111/febs.12778.
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Sehl, T;
Hailes, HC;
Ward, JM;
Menyes, U;
Pohl, M;
Rother, D;
(2014)
Efficient 2-step biocatalytic strategies for the synthesis of all nor(pseudo) ephedrine isomers.
Green Chemistry
, 16
(6)
pp. 3341-3348.
10.1039/c4gc00100a.
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Sexton, NJ;
Cooper, RP;
(2014)
An architecturally constrained model of random number generation and its application to modeling the effect of generation rate.
Frontiers in Psychology
, 5
, Article 670. 10.3389/fpsyg.2014.00670.
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Siganporia, CC;
Ghosh, S;
Daszkowski, T;
Papageorgiou, LG;
Farid, SS;
(2014)
Capacity planning for batch and perfusion bioprocesses across multiple biopharmaceutical facilities.
Biotechnology Progress
, 30
(3)
pp. 594-606.
10.1002/btpr.1860.
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Simaria, AS;
Hassan, S;
Varadaraju, H;
Rowley, J;
Warren, K;
Vanek, P;
Farid, SS;
(2014)
Allogeneic cell therapy bioprocess economics and optimisation: Single-use cell expansion technologies.
Biotechnol Bioeng
, 111
(1)
pp. 69-83.
10.1002/bit.25008.
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Tagalakis, AD;
Lee, DH;
Bienemann, AS;
Zhou, H;
Munye, MM;
Saraiva, L;
McCarthy, D;
... Hart, SL; + view all
(2014)
Multifunctional, self-assembling anionic peptide-lipid nanocomplexes for targeted siRNA delivery.
Biomaterials
, 35
(29)
pp. 8406-8415.
10.1016/j.biomaterials.2014.06.003.
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Tavakoli-Keshe, R;
Phillips, JJ;
Turner, R;
Bracewell, DG;
(2014)
Understanding the Relationship Between Biotherapeutic Protein Stability and Solid-Liquid Interfacial Shear in Constant Region Mutants of IgG1 and IgG4.
J Pharm Sci
, 103
(2)
pp. 437-444.
10.1002/jps.23822.
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Wu, T;
Zhou, Y;
(2014)
An Intelligent Automation Platform for Rapid Bioprocess Design.
J Lab Autom
, 19
(4)
pp. 381-393.
10.1177/2211068213499756.
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Yang, Y;
Farid, SS;
Thornhill, NF;
(2014)
Data mining for rapid prediction of facility fit and debottlenecking of biomanufacturing facilities.
J Biotechnol
, 179
pp. 17-25.
10.1016/j.jbiotec.2014.03.004.
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Thesis
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Abdul Halim, AB;
(2014)
In vitro metabolic pathway construction in an immobilised enzyme microreactor (IEMR).
Doctoral thesis (PhD), UCL (University College London).
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Braun Galleani, SC;
(2014)
Exploring the potential for recombinant protein production in microalgae.
Doctoral thesis , UCL (University College London).
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Chatel, A;
(2014)
Development and use of ultra scale-down methodologies to improve rate and quality of bioprocess discoveries.
Doctoral thesis , UCL (University College London).
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Dimitriadou, E;
(2014)
Redesign of calcium-regulated protein aequorin towards the development of a novel ion bioreporter.
Doctoral thesis , UCL (University College London).
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Du, C;
(2014)
Bioconversion of lignin degradation products into value-added chemicals.
Doctoral thesis , UCL (University College London).
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Hemsley, AL;
(2014)
The effect of mechanical and shear forces on embryonic stem cells.
Doctoral thesis , UCL (University College London).
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Hughson, MD;
(2014)
Micro-scale vaccine bioprocessing of a Japanese Encephalitis Virus vaccine.
Doctoral thesis , UCL (University College London).
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Lebre, PHB;
(2014)
Evaluation of Staphylococcus carnosus as an Alternative Host Organism for Whole-Cell Biocatalysis.
Doctoral thesis , UCL (University College London).
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Moens, NCH;
(2014)
Expansion and differentiation of human embryonic stem cells on an automated microwell platform.
Doctoral thesis , UCL (University College London).
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Ng, CKS;
(2014)
Optimal design, operation and control of sequential multi-column chromatography for separation of biomolecules.
Doctoral thesis , UCL (University College London).
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Payongsri, P;
(2014)
Synthetic biology approaches for the production of chiral aminoalcohols in engineered E. coli strains.
Doctoral thesis (PhD), UCL (University College London).
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Perez Pardo, MA;
(2014)
Characterisation of a biosensor surface for use with scale-down technologies in the process monitoring of Escherichia coli antibody fragment production.
Doctoral thesis , UCL (University College London).
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Pollock, JE;
(2014)
Evaluating the Potential of Continuous Processes for Monoclonal Antibodies: Economic, Environmental and Operational Feasibility.
Doctoral thesis , UCL (University College London).
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Rahimi Fard Jahromi, R;
(2014)
Evolutionary and Mutagenesis Studies Of E.coli Transketolase To Guide Further Protein Engineering.
Doctoral thesis , UCL (University College London).
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Randone, P;
(2014)
Bioprocess Studies of Biomass and Recombinant Protein Production by the Methylotrophic Yeast Pichia Pastoris.
Doctoral thesis , UCL (University College London).
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Silk, NJ;
(2014)
High throughput approaches to mammalian cell culture process development.
Doctoral thesis , UCL (University College London).
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Super, ASM;
(2014)
Oxygen monitoring in a microfluidic culture device for stem cell bioprocess development.
Doctoral thesis , UCL (University College London).
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Tarrant, RDR;
(2014)
Host Cell Protein Characterisation during the Downstream Processing of Monoclonal Antibodies from Mammalian Cells.
Doctoral thesis , UCL (University College London).
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Villegas Torres, MF;
(2014)
Design and characterization of novel biocatalytic cascades for chiral amino alcohol synthesis.
Doctoral thesis , UCL (University College London).
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Xu, Y;
(2014)
Exploring the potential of microalgae as a source for bioenergy production.
Doctoral thesis , UCL (University College London).
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