Browse by UCL people
Group by: Type | Date
Jump to: Article
Number of items: 50.
Article
Anguita, E;
Gupta, R;
Olariu, V;
Valk, PJ;
Peterson, C;
Delwel, R;
Enver, T;
(2016)
A somatic mutation of GFI1B identified in leukemia alters cell fate via a SPI1 (PU.1) centered genetic regulatory network.
Developmental Biology
, 411
(2)
pp. 277-286.
10.1016/j.ydbio.2016.02.002.
|
 |
|
Böiers, C;
Richardson, SE;
Laycock, E;
Zriwil, A;
Turati, VA;
Brown, J;
Wray, JP;
... Enver, T; + view all
(2018)
A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.
Developmental Cell
, 44
(3)
pp. 362-377.
10.1016/j.devcel.2017.12.005.
|
|
Boto, C;
Quartin, E;
Cai, Y;
Martin-Lorenzo, A;
Garcia Cenador, MB;
Pinto, S;
Gupta, R;
... Ferreira, L; + view all
(2017)
Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation.
Nature Communications
, 8
, Article 15204. 10.1038/ncomms15204.
|
|
Cattin, AL;
Burden, JJ;
Van Emmenis, L;
Mackenzie, FE;
Hoving, JJ;
Garcia Calavia, N;
Guo, Y;
... Lloyd, AC; + view all
(2015)
Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves.
Cell
, 162
(5)
pp. 1127-1139.
10.1016/j.cell.2015.07.021.
|
|
|
Chen, W;
Morabito, SJ;
Kessenbrock, K;
Enver, T;
Meyer, KB;
Teschendorff, AE;
(2019)
Single-cell landscape in mammary epithelium reveals bipotent-like cells associated with breast cancer risk and outcome.
Communications Biology
, 2
, Article 306. 10.1038/s42003-019-0554-8.
|
|
|
Chickarmane, V;
Enver, T;
Peterson, C;
(2009)
Computational Modeling of the Hematopoietic Erythroid-Myeloid Switch Reveals Insights into Cooperativity, Priming, and Irreversibility.
PLOS COMPUT BIOL
, 5
(1)
, Article e1000268. 10.1371/journal.pcbi.1000268.
|
 |
|
Cui, S;
McGranahan, N;
Gao, J;
Chen, P;
Jiang, W;
Yang, L;
Ma, L;
... Wu, S; + view all
(2023)
Tracking the evolution of esophageal squamous cell carcinoma under dynamic immune selection by multi-omics sequencing.
Nature Communications
, 14
(1)
, Article 892. 10.1038/s41467-023-36558-1.
|
|
das Neves, RP;
Jones, NS;
Andreu, L;
Gupta, R;
Enver, T;
Iborra, FJ;
(2010)
Connecting Variability in Global Transcription Rate to Mitochondrial Variability.
PLoS Biology
, 8
(12)
, Article e1000560. 10.1371/journal.pbio.1000560.
|
|
|
Diot, A;
Agnew, T;
Sanderson, J;
Liao, C;
Carver, J;
Neves, RPD;
Gupta, R;
... Poulton, J; + view all
(2018)
Validating the RedMIT/GFP-LC3 Mouse Model by Studying Mitophagy in Autosomal Dominant Optic Atrophy Due to the OPA1Q285STOP Mutation.
Frontiers in Cell and Developmental Biology
, 6
, Article 103. 10.3389/fcell.2018.00103.
|
|
|
Ebinger, S;
Oezdemir, EZ;
Ziegenhain, C;
Tiedt, S;
Alves, CC;
Grunert, M;
Dworzak, M;
... Jeremias, I; + view all
(2016)
Characterization of Rare, Dormant, and Therapy-Resistant Cells in Acute Lymphoblastic Leukemia.
Cancer Cell
, 30
(6)
pp. 849-862.
10.1016/j.ccell.2016.11.002.
|
|
|
Ferreira, R;
Napoli, J;
Enver, T;
Bernardino, L;
Ferreira, L;
(2020)
Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine.
Nature Communications
, 11
, Article 4265. 10.1038/s41467-020-18042-2.
|
|
|
Gaizley, Emily J;
Chen, Xiuyuan;
Bhamra, Amandeep;
Enver, Tariq;
Surinova, Silvia;
(2025)
Multiplexed phosphoproteomics of low cell numbers using SPARCE.
Communications Biology
, 8
, Article 666. 10.1038/s42003-025-08068-x.
|
|
|
Gerber, JP;
Russ, J;
Chandrasekar, V;
Offermann, N;
Lee, H-M;
Spear, S;
Guzzi, N;
... Salomoni, P; + view all
(2021)
Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation.
Nature Cell Biology
10.1038/s41556-021-00774-y.
|
|
|
Geron, Ifat;
Savino, Angela Maria;
Fishman, Hila;
Tal, Noa;
Brown, John;
Turati, Virginia A;
James, Chela;
... Izraeli, Shai; + view all
(2022)
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia.
Nature Communications
, 13
, Article 659. 10.1038/s41467-022-28218-7.
|
|
|
Ghorani, E;
Reading, JL;
Henry, JY;
Massy, MRD;
Rosenthal, R;
Turati, V;
Joshi, K;
... Quezada, SA; + view all
(2020)
The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
Nature Cancer
, 1
(5)
pp. 546-561.
10.1038/s43018-020-0066-y.
|
|
Guibentif, C;
Ronn, RE;
Boiers, C;
Lang, S;
Saxena, S;
Soneji, S;
Enver, T;
... Woods, N-B; + view all
(2017)
Single-Cell Analysis Identifies Distinct Stages of Human Endothelial-to-Hematopoietic Transition.
Cell Reports
, 19
(1)
pp. 10-19.
10.1016/j.celrep.2017.03.023.
|
|
|
Gupta, R;
Gant, VA;
Williams, B;
Enver, T;
(2020)
Increased Complement Receptor-3 levels in monocytes and granulocytes distinguish COVID-19 patients with pneumonia from those with mild symptoms.
International Journal of Infectious Diseases
10.1016/j.ijid.2020.08.004.
(In press).
|
|
|
Gupta, R;
Turati, V;
Brian, D;
Thrussel, C;
Wilbourn, B;
May, G;
Enver, T;
(2020)
Nov/CCN3 Enhances Cord Blood Engraftment by Rapidly Recruiting Latent Human Stem Cell Activity.
Cell Stem Cell
10.1016/j.stem.2020.02.012.
(In press).
|
|
Johnston, IG;
Gaal, B;
Neves, RP;
Enver, T;
Iborra, FJ;
Jones, NS;
(2012)
Mitochondrial variability as a source of extrinsic cellular noise.
PLoS Comput Biol
, 8
(3)
, Article e1002416. 10.1371/journal.pcbi.1002416.
|
|
|
Joshi, K;
Robert de Massy, M;
Ismail, M;
Reading, JL;
Uddin, I;
Woolston, A;
Hatipoglu, E;
... Chain, B; + view all
(2019)
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Nature Medicine
, 25
pp. 1549-1559.
10.1038/s41591-019-0592-2.
|
|
Kato, I;
Nishinaka, Y;
Nakamura, M;
Akarca, AU;
Niwa, A;
Ozawa, H;
Yoshida, K;
... Enver, T; + view all
(2017)
Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA.
Blood
, 129
(23)
pp. 3126-3129.
10.1182/blood-2016-06-721712.
|
|
Kenny, PA;
Enver, T;
Ashworth, A;
(2005)
Receptor and secreted targets of Wnt-I/beta-catenin signalling in mouse mammary epithelial cells.
BMC Cancer
, 5
, Article 3. 10.1186/1471-2407-5-3.
|
|
|
Kenny, PA;
Enver, T;
Ashworth, A;
(2002)
Retroviral vectors for establishing tetracycline-regulated gene expression in an otherwise recalcitrant cell line.
BMC MOL BIOL
, 3
, Article 13. 10.1186/1471-2199-3-13.
|
|
|
Lai, AG;
Pasea, L;
Banerjee, A;
Hall, G;
Denaxas, S;
Chang, WH;
Katsoulis, M;
... Hemingway, H; + view all
(2020)
Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study.
BMJ Open
, 10
(11)
, Article e043828. 10.1136/bmjopen-2020-043828.
|
|
|
Lima, AF;
May, G;
Colunga, J;
Pedreiro, S;
Paiva, A;
Ferreira, L;
Enver, T;
... Pires das Neves, R; + view all
(2018)
Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation.
Scientific Reports
, 8
, Article 7210. 10.1038/s41598-018-25517-2.
|
|
|
Lima, AF;
May, G;
Díaz-Colunga, J;
Pedreiro, S;
Paiva, A;
Ferreira, L;
Enver, T;
... Pires das Neves, R; + view all
(2018)
Author Correction: Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation.
[Corrigendum].
Scientific Reportsvolume
, 8
, Article 11303. 10.1038/s41598-018-29328-3.
|
|
|
Litchfield, K;
Reading, JL;
Puttick, C;
Thakkar, K;
Abbosh, C;
Bentham, R;
Watkins, TBK;
... Swanton, C; + view all
(2021)
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.
Cell
, 184
(3)
596-614.e14.
10.1016/j.cell.2021.01.002.
|
|
|
Litchfield, K;
Stanislaw, S;
Spain, L;
Gallegos, LL;
Rowan, A;
Schnidrig, D;
Rosenbaum, H;
... Turajlic, S; + view all
(2020)
Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue.
Cell Reports
, 31
(5)
p. 107550.
10.1016/j.celrep.2020.107550.
|
|
Liu, TH;
Tang, YJ;
Huang, Y;
Wang, L;
Guo, XL;
Mi, JQ;
Liu, LG;
... Hong, DL; + view all
(2017)
Expression of the fetal hematopoiesis regulator FEV indicates leukemias of prenatal origin.
Leukemia
, 31
(5)
pp. 1079-1086.
10.1038/leu.2016.313.
|
|
Mansell, E;
Sigurdsson, V;
Deltcheva, E;
Brown, J;
James, C;
Miharada, K;
Soneji, S;
... Enver, T; + view all
(2020)
Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function.
Cell Stem Cell
10.1016/j.stem.2020.09.018.
(In press).
|
|
|
Marshall, A;
Kasturiarachchi, J;
Datta, P;
Guo, Y;
Deltcheva, E;
James, C;
Brown, J;
... Nimmo, R; + view all
(2020)
Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genes.
Scientific Reports
, 10
, Article 19390. 10.1038/s41598-020-76218-8.
|
|
May, G;
Soneji, S;
Tipping, AJ;
Teles, J;
McGowan, SJ;
Wu, M;
Guo, Y;
... Enver, T; + view all
(2013)
Dynamic Analysis of Gene Expression and Genome-wide Transcription Factor Binding during Lineage Specification of Multipotent Progenitors.
Cell Stem Cell
, 13
(6)
pp. 754-768.
10.1016/j.stem.2013.09.003.
|
|
|
Migueles, RP;
Shaw, L;
Rodrigues, NP;
May, G;
Henseleit, K;
Anderson, KGV;
Goker, H;
... Enver, T; + view all
(2017)
Transcriptional regulation of Hhex in hematopoiesis and hematopoietic stem cell ontogeny.
Developmental Biology
, 424
(2)
pp. 236-245.
10.1016/j.ydbio.2016.12.021.
|
|
Peltzer, N;
Darding, M;
Montinaro, A;
Draber, P;
Draberova, H;
Kupka, S;
Rieser, E;
... Walczak, H; + view all
(2018)
LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.
Nature
, 557
(7703)
pp. 112-117.
10.1038/s41586-018-0064-8.
|
|
Richardson, SE;
Ghazanfari, R;
Chhetri, J;
Enver, T;
Böiers, C;
(2021)
In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture.
STAR Protocols
, 2
(2)
, Article 100420. 10.1016/j.xpro.2021.100420.
|
|
|
Roberts, Luke B;
Jowett, Geraldine M;
Read, Emily;
Zabinski, Tomas;
Berkachy, Rita;
Selkirk, Murray E;
Jackson, Ian;
... Lord, Graham M; + view all
(2021)
MicroRNA-142 Critically Regulates Group 2 Innate Lymphoid Cell Homeostasis and Function.
The Journal of Immunology
, 206
(11)
pp. 2725-2739.
10.4049/jimmunol.2000647.
|
|
Rodríguez-Hernández, Guillermo;
Casado-García, Ana;
Isidro-Hernández, Marta;
Picard, Daniel;
Raboso-Gallego, Javier;
Alemán-Arteaga, Silvia;
Orfao, Alberto;
... Vicente-Dueñas, Carolina; + view all
(2021)
The Second Oncogenic Hit Determines the Cell Fate of ETV6-RUNX1 Positive Leukemia.
Frontiers in Cell and Developmental Biology
, 9
, Article 704591. 10.3389/fcell.2021.704591.
|
|
Rydström, A;
Grahn, THM;
Niroula, A;
Mansell, E;
van der Garde, M;
Pertesi, M;
Subramaniam, A;
... Karlsson, S; + view all
(2023)
Functional and molecular profiling of hematopoietic stem cells during regeneration.
Experimental Hematology
10.1016/j.exphem.2023.08.010.
|
|
|
Stavish, D;
Böiers, C;
Price, C;
Frith, TJR;
Halliwell, J;
Saldaña-Guerrero, I;
Wray, J;
... Enver, T; + view all
(2020)
Generation and trapping of a mesoderm biased state of human pluripotency.
Nature Communications
, 11
, Article 4989. 10.1038/s41467-020-18727-8.
|
|
|
Stunnenberg, HG;
Abrignani, S;
Adams, D;
de Almeida, M;
Altucci, L;
Amin, V;
Amit, I;
... Kim, SC; + view all
(2016)
The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery.
Cell
, 167
(5)
pp. 1145-1149.
10.1016/j.cell.2016.11.007.
|
|
Teles, J;
Pina, C;
Edén, P;
Ohlsson, M;
Enver, T;
Peterson, C;
(2013)
Transcriptional regulation of lineage commitment - a stochastic model of cell fate decisions.
PLoS Computational Biology
, 9
(8)
, Article e1003197. 10.1371/journal.pcbi.1003197.
|
|
|
Teschendorff, AE;
Enver, T;
(2017)
Single-cell entropy for accurate estimation of differentiation potency from a cell's transcriptome.
Nature Communications
, 8
, Article 15599. 10.1038/ncomms15599.
|
|
Tsuzuki, S;
Hong, DL;
Gupta, R;
Matsuo, K;
Seto, M;
Enver, T;
(2007)
Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1.
PLoS Medicine
, 4
(5)
, Article e172. 10.1371/journal.pmed.0040172.
|
|
|
Tsuzuki, S;
Seto, M;
Hong, D;
Gupta, R;
Enver, T;
Matsuo, K;
(2007)
Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1.
PLoS Medicine
, 4
(5)
, Article e172. 10.1371/journal.pmed.0040172.
|
|
|
Turati, VA;
Guerra-Assunção, JA;
Potter, NE;
Gupta, R;
Ecker, S;
Daneviciute, A;
Tarabichi, M;
... Enver, T; + view all
(2021)
Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia.
Nature Cancer
, 2
pp. 835-852.
10.1038/s43018-021-00219-3.
|
|
Wray, Jason P;
Deltcheva, Elitza M;
Boiers, Charlotta;
Richardson, Simon Е;
Chhetri, Jyoti Bikram;
Brown, John;
Gagrica, Sladjana;
... Enver, Tariq; + view all
(2022)
Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability.
Nature Communications
, 13
, Article 7124. 10.1038/s41467-022-34653-3.
|
|
Yogev, O;
Henderson, S;
Hayes, MJ;
Marelli, SS;
Ofir-Birin, Y;
Regev-Rudzki, N;
Herrero, J;
(2017)
Herpesviruses shape tumour microenvironment through exosomal transfer of viral microRNAs.
PLoS Pathogens
, 13
(8)
, Article e1006524. 10.1371/journal.ppat.1006524.
|
|
|
Yogev, O;
Lagos, D;
Enver, T;
Boshoff, C;
(2014)
Kaposi's Sarcoma Herpesvirus MicroRNAs Induce Metabolic Transformation of Infected Cells.
PLoS Pathog
, 10
(9)
, Article e1004400 . 10.1371/journal.ppat.1004400.
|
|
|
Yuan, G-C;
Cai, L;
Elowitz, M;
Enver, T;
Fan, G;
Guo, G;
Irizarry, R;
... Tirosh, I; + view all
(2017)
Challenges and emerging directions in single-cell analysis.
Genome Biology
, 18
, Article 84. 10.1186/s13059-017-1218-y.
|
|
|
Zhang, Xiaoyan;
Yang, Ling;
Lei, Wanjun;
Hou, Qiang;
Huang, Ming;
Zhou, Rongjing;
Enver, Tariq;
(2022)
Single-cell sequencing reveals CD133+CD44--originating evolution and novel stemness related variants in human colorectal cancer.
EBioMedicine
, 82
, Article 104125. 10.1016/j.ebiom.2022.104125.
|
