Browse by UCL people
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Number of items: 48.
Article
Davis, BM;
Pahlitzsch, M;
Guo, L;
Balendra, S;
Shah, P;
Ravindran, N;
Malaguarnera, G;
... Cordeiro, MF; + view all
(2018)
Topical Curcumin Nanocarriers are Neuroprotective in Eye Disease.
Scientific Reports
, 8
, Article 11066. 10.1038/s41598-018-29393-8.
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Dinh, T;
Zia, Q;
Zubair, S;
Stapleton, P;
Singh, R;
Owais, M;
Somavarapu, S;
(2017)
Novel biodegradable poly(gamma-glutamic acid)–amphotericin B complexes show promise as improved amphotericin B formulations.
Nanomedicine: Nanotechnology, Biology and Medicine
, 13
(5)
pp. 1773-1783.
10.1016/j.nano.2017.02.003.
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Elsaid, N;
Jackson, TL;
Elsaid, Z;
Alqathania, A;
Somavarapu, S;
(2016)
PLGA Microparticles Entrapping Chitosan-Based Nanoparticles for the Ocular Delivery of Ranibizumab.
Molecular Pharmaceutics
, 13
(9)
pp. 2923-2940.
10.1021/acs.molpharmaceut.6b00335.
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Elsaid, Z;
Taylor, KM;
Puri, S;
Eberlein, CA;
Al-Jamal, K;
Bai, J;
Klippstein, R;
... Somavarapu, S; + view all
(2017)
Mixed micelles of lipoic acid-chitosan-poly(ethylene glycol) and distearoylphosphatidylethanolamine-poly(ethylene glycol) for tumor delivery.
European Journal of Pharmaceutical Sciences
, 101
pp. 228-242.
10.1016/j.ejps.2017.02.001.
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Farheen, S;
Oanz, AM;
Khan, N;
Umar, MS;
Jamal, F;
Altaf, I;
Kashif, M;
... Owais, M; + view all
(2022)
Fabrication of Microbicidal Silver Nanoparticles: Green Synthesis and Implications in the Containment of Bacterial Biofilm on Orthodontal Appliances.
Frontiers in Nanotechnology
, 4
, Article 780783. 10.3389/fnano.2022.780783.
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Ho Yi Chan, Stefanie;
Sheikh, Khalid;
Zariwala, Mohammed Gulrez;
Somavarapu, Satyanarayana;
(2023)
Dry powder formulation of azithromycin for COVID-19 therapeutics.
Journal of Microencapsulation
, 40
(4)
pp. 217-232.
10.1080/02652048.2023.2175924.
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Jamal, Fauzia;
Ahmed, Ghufran;
Farazuddin, Mohammad;
Altaf, Ishrat;
Farheen, Saba;
Zia, Qamar;
Azhar, Asim;
... Owais, Mohammad; + view all
(2023)
Potential of siRNA-Bearing Subtilosomes in the Treatment of Diethylnitrosamine-Induced Hepatocellular Carcinoma.
Molecules
, 28
(5)
, Article 2191. 10.3390/molecules28052191.
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Jiang, C;
Bai, R;
Somavarapu, S;
(2025)
Inhalable TPGS/DPPC Micelles Coloaded with Curcumin and Icariin for Targeted Lung Cancer Therapy.
ACS Omega
, 10
(15)
pp. 15400-15411.
10.1021/acsomega.5c00008.
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Jiang, Chengwei;
Somavarapu, Satyanarayana;
(2024)
Design and development of DSPE-PEG2000/DPPC disk-like micelles for targeted delivery of icariin phytochemical in pulmonary fibrosis.
International Journal of Pharmaceutics
, 667
(Pt A)
, Article 124837. 10.1016/j.ijpharm.2024.124837.
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Kunda, NK;
Alfagih, IM;
Dennison, SR;
Tawfeek, HM;
Somavarapu, S;
Hutcheon, GA;
Saleem, IY;
(2015)
Bovine Serum Albumin Adsorbed PGA-co-PDL Nanocarriers for Vaccine Delivery via Dry Powder Inhalation.
Pharmaceutical Research
, 32
(4)
pp. 1341-1353.
10.1007/s11095-014-1538-5.
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Kunda, NK;
Alfagih, IM;
Miyaji, EN;
Figueiredo, DB;
Goncalves, VM;
Ferreira, DM;
Dennison, SR;
... Saleem, IY; + view all
(2015)
Pulmonary dry powder vaccine of pneumococcal antigen loaded nanoparticles.
International Journal of Pharmaceutics
, 495
(2)
pp. 903-912.
10.1016/j.ijpharm.2015.09.034.
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Lee, Dani Do Hyang;
Cardinale, Daniela;
Terakosolphan, Wachirun;
Sornsute, Acom;
Radhakrishnan, Priya;
Coppel, Jonathan;
Smith, Claire M;
... O'Callaghan, Christopher; + view all
(2021)
Fluticasone Particles Bind to Motile Respiratory Cilia: A Mechanism for Enhanced Lung and Systemic Exposure?
Journal of Aerosol Medicine and Pulmonary Drug Delivery
, 34
(3)
pp. 181-188.
10.1089/jamp.2020.1598.
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Lee, DDH;
Cardinale, D;
Nigro, E;
Butler, CR;
Rutman, A;
Fassad, MR;
Hirst, RA;
... O'Callaghan, C; + view all
(2021)
Higher throughput drug screening for rare respiratory diseases: Readthrough therapy in primary ciliary dyskinesia.
European Respiratory Journal
10.1183/13993003.00455-2020.
(In press).
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Malamatari, M;
Somavarapu, S;
Taylor, KMG;
Buckton, G;
(2016)
Solidification of nanosuspensions for the production of solid oral dosage forms and inhalable dry powders.
Expert Opinion on Drug Delivery
, 13
(3)
pp. 435-450.
10.1517/17425247.2016.1142524.
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Merchant, Z;
Buckton, G;
Taylor, KM;
Stapleton, P;
Saleem, IY;
Gulrez Zariwala, M;
Somavarapu, S;
(2016)
A new era of pulmonary delivery of nano-antimicrobial therapeutics to treat chronic pulmonary infections.
Current Pharmaceutical Design
, 22
(17)
pp. 2577-2598.
10.2174/1381612822666160317142139.
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Merchant, Z;
Taylor, KM;
Stapleton, P;
Razak, SA;
Kunda, N;
Alfagih, I;
Sheikh, K;
... Somavarapu, S; + view all
(2014)
Engineering hydrophobically modified chitosan for enhancing the dispersion of respirable microparticles of levofloxacin.
European Journal of Pharmaceutics and Biopharmaceutics
, 88
(3)
pp. 816-829.
10.1016/j.ejpb.2014.09.005.
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Mokhtar, H;
Biffar, L;
Somavarapu, S;
Frossard, J-P;
McGowan, S;
Pedrera, M;
Strong, R;
... Graham, SP; + view all
(2017)
Evaluation of hydrophobic chitosan-based particulate formulations of porcine reproductive and respiratory syndrome virus vaccine candidate T cell antigens.
Veterinary Microbiology
, 209
pp. 66-74.
10.1016/j.vetmic.2017.01.037.
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Mokhtar, H;
Pedrera, M;
Frossard, J-P;
Biffar, L;
Hammer, SE;
Kvisgaard, LK;
Larsen, LE;
... Graham, SP; + view all
(2016)
The Non-structural Protein 5 and Matrix Protein Are Antigenic Targets of T Cell Immunity to Genotype 1 Porcine Reproductive and Respiratory Syndrome Viruses.
Frontiers In Immunology
, 7
, Article 40. 10.3389/fimmu.2016.00040.
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Mursaleen, L;
Chan, SHY;
Noble, B;
Somavarapu, S;
Zariwala, MG;
(2023)
Curcumin and N-Acetylcysteine Nanocarriers Alone or Combined with Deferoxamine Target the Mitochondria and Protect against Neurotoxicity and Oxidative Stress in a Co-Culture Model of Parkinson’s Disease.
Antioxidants
, 12
(1)
, Article 130. 10.3390/antiox12010130.
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Mursaleen, L;
Noble, B;
Chan, SHY;
Somavarapu, S;
Zariwala, MG;
(2020)
N-Acetylcysteine Nanocarriers Protect against Oxidative Stress in a Cellular Model of Parkinson's Disease.
Antioxidants
, 9
(7)
, Article 600. 10.3390/antiox9070600.
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Mursaleen, L;
Noble, B;
Somavarapu, S;
Zariwala, MG;
(2021)
Micellar nanocarriers of hydroxytyrosol are protective against parkinson’s related oxidative stress in an in vitro hcmec/d3‐sh‐sy5y co‐culture system.
Antioxidants
, 10
(6)
10.3390/antiox10060887.
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Nardi, M;
Brocchini, S;
Somavarapu, S;
Procopio, A;
(2023)
Hydroxytyrosol oleate: A promising neuroprotective nanocarrier delivery system of oleuropein and derivatives.
International Journal of Pharmaceutics
, 631
, Article 122498. 10.1016/j.ijpharm.2022.122498.
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Nardi, Monica;
Sarubbi, Emiliana;
Somavarapu, Satyanarayana;
(2022)
Eco-Friendly Synthesis of PEtOz-PA: A Promising Polymer for the Formulation of Curcumin-Loaded Micelles.
Molecules
, 27
(12)
, Article 3788. 10.3390/molecules27123788.
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Nimmano, N;
Somavarapu, S;
Taylor, K;
(2018)
Aerosol characterisation of nebulised liposomes co-loaded with erlotinib and genistein using an abbreviated cascade impactor method.
International Journal of Pharmaceutics
, 542
(1-2)
pp. 8-17.
10.1016/j.ijpharm.2018.02.035.
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Noor, NM;
Umar, S;
Abdul-Aziz, A;
Sheikh, K;
Somavarapu, S;
(2022)
Engineered Dutasteride-Lipid Based Nanoparticle (DST-LNP) System Using Oleic and Stearic Acid for Topical Delivery.
Bioengineering
, 9
(1)
, Article 11. 10.3390/bioengineering9010011.
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Noor, NM;
Aziz, AA;
Sheikh, K;
Somavarapu, S;
Taylor, K;
(2020)
In vitro Performance of Dutasteride-Nanostructured Lipid Carriers coated with Lauric Acid-Chitosan Oligomer for Dermal Delivery.
Pharmaceutics
, 12
(10)
, Article 994. 10.3390/pharmaceutics12100994.
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Noor, NM;
Sheikh, K;
Somavarapu, S;
Taylor, KM;
(2017)
Preparation and Characterization of Dutasteride-loaded Nanostructured Lipid Carriers coated with Stearic Acid-Chitosan Oligomer for Topical Delivery.
European Journal of Pharmaceutics and Biopharmaceutics
, 117
pp. 372-384.
10.1016/j.ejpb.2017.04.012.
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Normando, EM;
Davis, BM;
De Groef, L;
Nizari, S;
Turner, LA;
Ravindran, N;
Pahlitzsch, M;
... Cordeiro, MF; + view all
(2016)
The retina as an early biomarker of neurodegeneration in a rotenone-induced model of Parkinson's disease: evidence for a neuroprotective effect of rosiglitazone in the eye and brain.
Acta Neuropathologica Communications
, 4
, Article 86. 10.1186/s40478-016-0346-z.
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Papay, ZE;
Kosa, A;
Boddi, B;
Merchant, Z;
Saleem, IY;
Zariwala, MG;
Klebovich, I;
... Antal, I; + view all
(2017)
Study on the Pulmonary Delivery System of Apigenin-Loaded Albumin Nanocarriers with Antioxidant Activity.
Journal of Aerosol Medicine and Pulmonary Drug Delivery
, 30
(4)
pp. 274-288.
10.1089/jamp.2016.1316.
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Petagine, Lucy;
Zariwala, Mohammed G;
Somavarapu, Satyanarayana;
Chan, Stefanie Ho Yi;
Kaya, Evrim A;
Patel, Vinood B;
(2025)
Oxidative stress in a cellular model of alcohol-related liver disease: protection using curcumin nanoformulations.
Scientific Reports
, 15
, Article 7752. 10.1038/s41598-025-91139-0.
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Petagine, Lucy;
Zariwala, Mohammed G;
Somavarapu, Satyanarayana;
Chan, Stefanie Ho Yi;
Patel, Vinood B;
(2025)
Curcumin Nanocarriers in the Protection Against Iron- and Alcohol-Induced Oxidative Stress in a Cellular Model of Liver Disease.
Biology
, 14
(5)
, Article 455. 10.3390/biology14050455.
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Petkar, KC;
Chavan, S;
Kunda, N;
Saleem, I;
Somavarapu, S;
Taylor, K;
Sawant, KK;
(2018)
Development of novel octanoyl chitosan nanoparticles for improved rifampicin pulmonary delivery: optimization by factorial design.
AAPS PharmSciTech
, 19
(4)
pp. 1758-1772.
10.1208/s12249-018-0972-9.
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Riitho, V;
Walters, AA;
Somavarapu, S;
Lamp, B;
Rümenapf, T;
Krey, T;
Rey, FA;
... Graham, SP; + view all
(2017)
Design and evaluation of the immunogenicity and efficacy of a biomimetic particulate formulation of viral antigens.
Scientific Reports
, 7
, Article 13743. 10.1038/s41598-017-13915-x.
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Sazhin, SS;
Rybdylova, O;
Pannala, AS;
Somavarapu, S;
Zaripov, SK;
(2018)
A new model for a drying droplet.
International Journal of Heat and Mass Transfer
, 122
pp. 451-458.
10.1016/j.ijheatmasstransfer.2018.01.094.
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Schiano, Elisabetta;
Novellino, Ettore;
Gámez Fernández, Marta María;
Tiekou Lorinczova, Helena;
Tenore, Gian Carlo;
Iannuzzo, Fortuna;
Patel, Vinood B;
... Zariwala, Mohammed Gulrez; + view all
(2023)
Antioxidant and Antidiabetic Properties of a Thinned-Nectarine-Based Nanoformulation in a Pancreatic β-Cell Line.
Antioxidants
, 13
(1)
, Article 63. 10.3390/antiox13010063.
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Shamsher, Ehtesham;
Khan, Reas S;
Davis, Benjamin M;
Dine, Kimberly;
Luong, Vy;
Somavarapu, Satyanarayana;
Cordeiro, M Francesca;
(2023)
Nanoparticles Enhance Solubility and Neuroprotective Effects of Resveratrol in Demyelinating Disease.
Neurotherapeutics
, 20
(4)
pp. 1138-1153.
10.1007/s13311-023-01378-0.
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Somavarapu, Satyanarayana;
Sornsute, Acom;
Trill, Jeanne;
Abdelhakim, Hend E;
Goonatilaka, Dinithi;
Pannala, Ananth S;
Taylor, Kevin MG;
(2023)
Engineering artesunate-loaded micelles using spray drying for pulmonary drug delivery.
Journal of Drug Delivery Science and Technology
, 86
, Article 104641. 10.1016/j.jddst.2023.104641.
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Srikantha, N;
Teijeiro-Gonzalez, Y;
Simpson, A;
Elsaid, N;
Somavarapu, S;
Suhling, K;
Jackson, TL;
(2022)
Determining vitreous viscosity using fluorescence recovery after photobleaching.
PLoS ONE
, 17
(2)
, Article e0261925. 10.1371/journal.pone.0261925.
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Taylor, K;
Malamatari, M;
Somavarapu, S;
Kachrimanis, K;
Bloxham, M;
Buckton, G;
(2016)
Preparation of theophylline inhalable microcomposite particles by wet milling and spray drying: the influence of mannitol as a co-milling agent.
International Journal of Pharmaceutics
, 514
(1)
pp. 200-211.
10.1016/j.ijpharm.2016.06.032.
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Taylor, K;
Malamatari, M;
Somavarapu, S;
Kachrimanis, K;
Buckton, G;
(2016)
Preparation of respirable nanoparticle agglomerates of the low melting and ductile drug ibuprofen: impact of formulation parameters.
Powder Technology
, 308
pp. 123-134.
10.1016/j.powtec.2016.12.007.
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Taylor, K;
Mohtar, N;
Sheikh, K;
Somavarapu, S;
(2016)
Design and development of dry powder Sulfobutylether-β-Cyclodextrin complex for pulmonary delivery of Fisetin.
European Journal of Pharmaceutics and Biopharmaceutics
, 113
pp. 1-10.
10.1016/j.ejpb.2016.11.036.
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Wagner, Q;
Offner, D;
Idoux-Gillet, Y;
Saleem, I;
Somavarapu, S;
Schwinte, P;
Benkirane-Jessel, N;
(2016)
Advanced nanostructured medical device combining mesenchymal cells and VEGF nanoparticles for enhanced engineered tissue vascularization.
Nanomedicine
, 11
(18)
pp. 2419-2430.
10.2217/nnm-2016-0189.
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Zariwala, MG;
Bendre, H;
Markiv, A;
Farnaud, S;
Renshaw, D;
Taylor, KMG;
Somavarapu, S;
(2018)
Hydrophobically-modified chitosan nanoliposomes for intestinal drug delivery.
International Journal of Nanomedicine
, 13
pp. 5837-5848.
10.2147/IJN.S166901.
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Book chapter
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Pápay, ZE;
Balogh, E;
Zariwala, MG;
Somavarapu, S;
Antal, I;
(2015)
Drug delivery approaches for apigenin: A review.
In: Stacks, N, (ed.)
Apigenin and Naringenin: Natural Sources, Pharmacology and Role in Cancer Prevention.
(pp. 1-20).
Nova: New York, NY, USA.
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Saleem, I;
Petkar, K;
Somavarapu, S;
(2017)
Rationale for Pulmonary Vaccine Delivery: Formulation and Device Considerations.
In:
Micro- and Nanotechnology in Vaccine Development.
(pp. 357-371).
Elsevier
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Conference item
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Alpar, HO;
Murdan, S;
Outschoorn, I;
Bramwell, VW;
Somavarapu, S;
(2003)
Quil-A - Chitosan: A novel mucosal adjuvant.
Presented at: MVADS Conference, Dublin, Republic of Ireland.
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Chavan, T;
Taylor, KMG;
Saleem, IY;
Randle, LE;
Elsaid, Z;
Somavarapu, S;
(2013)
O-palmitoyl chitosan-PEG micelles for amphotericin B delivery to the lung.
Presented at: Aerosol Society Drug Delivery to the Lungs Conference 2011 (DDL22), Edinburgh, UK.
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Kunda, N;
Somavarapu, S;
Hutcheon, G;
Saleem, I;
(2013)
Protein Adsorbed PGA-co-PDL Nanocarriers for Vaccine Delivery.
Presented at: AAPS 2013, San Antonio, Texas, USA.
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