Browse by UCL people
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Number of items: 47.
Article
Al Awabdh, S;
Gupta-Agarwal, S;
Sheehan, DF;
Muir, J;
Norkett, R;
Twelvetrees, AE;
Griffin, LD;
(2016)
Neuronal activity mediated regulation of glutamate transporter GLT-1 surface diffusion in rat astrocytes in dissociated and slice cultures.
Glia
, 64
(7)
pp. 1252-1264.
10.1002/glia.22997.
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Augustin, H;
McGourty, K;
Steinert, JR;
Cochemé, HM;
Adcott, J;
Cabecinha, M;
Vincent, A;
... Partridge, L; + view all
(2017)
Myostatin-like proteins regulate synaptic function and neuronal morphology.
Development
, 144
pp. 2445-2455.
10.1242/dev.152975.
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Birsa, N;
Norkett, R;
Wauer, T;
Mevissen, TE;
Wu, HC;
Foltynie, T;
Bhatia, K;
... Kittler, JT; + view all
(2014)
Lysine 27 Ubiquitination of the Mitochondrial Transport Protein Miro Is Dependent on Serine 65 of the Parkin Ubiquitin Ligase.
J Biol Chem
, 289
(21)
pp. 14569-14582.
10.1074/jbc.M114.563031.
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Chen, GJ;
Kittler, JT;
Moss, SJ;
Yan, Z;
(2006)
Dopamine D-3 receptors regulate GABA(A) receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens.
J NEUROSCI
, 26
(9)
2513 - 2521.
10.1523/JNEUROSCI.4712-05.2006.
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Covill-Cooke, C;
Toncheva, VS;
Kittler, JT;
(2020)
Regulation of peroxisomal trafficking and distribution.
Cellular and Molecular Life Sciences
, 78
pp. 1929-1941.
10.1007/s00018-020-03687-5.
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Covill-Cooke, Christian;
Kwizera, Brian;
López-Doménech, Guillermo;
Thompson, Caleb OD;
Cheung, Ngaam J;
Cerezo, Ema;
Peterka, Martin;
... Kornmann, Benoît; + view all
(2024)
Shared structural features of Miro binding control mitochondrial homeostasis.
The EMBO Journal
10.1038/s44318-024-00028-1.
(In press).
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Covill-Cooke, C;
Howden, JH;
Birsa, N;
Kittler, JT;
(2018)
Ubiquitination at the mitochondria in neuronal health and disease.
Neurochemistry International
, 117
pp. 55-64.
10.1016/j.neuint.2017.07.003.
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Covill-Cooke, C;
Toncheva, VS;
Drew, J;
Birsa, N;
López-Doménech, G;
Kittler, JT;
(2020)
Peroxisomal fission is modulated by the mitochondrial Rho-GTPases, Miro1 and Miro2.
EMBO Reports
, Article e49865. 10.15252/embr.201949865.
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Davenport, EC;
Pendolino, V;
Kontou, G;
McGee, TP;
Sheehan, DF;
López-Doménech, G;
Farrant, M;
(2017)
An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABAA Receptors.
Cell Reports
, 21
(1)
pp. 70-83.
10.1016/j.celrep.2017.09.025.
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Davenport, EC;
Szulc, BR;
Drew, J;
Taylor, J;
Morgan, T;
Higgs, NF;
López-Doménech, G;
(2019)
Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition.
Cell Reports
, 26
(8)
2037-2051.e6.
10.1016/j.celrep.2019.01.092.
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Devine, Michael J;
Szulc, Blanka R;
Howden, Jack H;
López-Doménech, Guillermo;
Ruiz, Arnaud;
Kittler, Josef T;
(2022)
Mitochondrial Ca²⁺ Uniporter haploinsufficiency enhances long-term potentiation at hippocampal mossy fibre synapses.
Journal of Cell Science
10.1242/jcs.259823.
(In press).
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Devine, MJ;
Kittler, JT;
(2018)
Mitochondria at the neuronal presynapse in health and disease.
[Review].
Nature Reviews Neuroscience
, 19
(2)
pp. 63-80.
10.1038/nrn.2017.170.
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Eckel, R;
Szulc, B;
Walker, MC;
Kittler, JTJ;
(2015)
Activation of calcineurin underlies altered trafficking of α2 subunit containing GABAA receptors during prolonged epileptiform activity.
Neuropharmacology
, 88
10.1016/j.neuropharm.2014.09.014.
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Ferreira, APA;
Casamento, A;
Carrillo Roas, S;
Halff, EF;
Panambalana, J;
Subramaniam, S;
Schützenhofer, K;
... Boucrot, E; + view all
(2021)
Cdk5 and GSK3β inhibit fast endophilin-mediated endocytosis.
Nature Communications
, 12
, Article 2424. 10.1038/s41467-021-22603-4.
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Gupta, Swati;
Bazargani, Narges;
Drew, James;
Howden, Jack;
Modi, Souvik;
Al Awabdh, Sana;
Marie, Hélène;
... Kittler, Josef T; + view all
(2022)
The non-adrenergic imidazoline-1 receptor protein nischarin is a key regulator of astrocyte glutamate uptake.
iScience
, 25
(4)
, Article 104127. 10.1016/j.isci.2022.104127.
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Halff, Els F;
Hannan, Saad;
Kwanthongdee, Jaturon;
Lesept, Flavie;
Smart, Trevor G;
Kittler, Josef T;
(2022)
Phosphorylation of neuroligin-2 by PKA regulates its cell surface abundance and synaptic stabilization.
Science Signaling
, 15
(739)
, Article eabg2505. 10.1126/scisignal.abg2505.
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Halff, EF;
Szulc, BR;
Lesept, F;
Kittler, JT;
(2019)
SNX27-Mediated Recycling of Neuroligin-2 Regulates Inhibitory Signaling.
Cell Reports
, 29
(9)
2599-2607.e6.
10.1016/j.celrep.2019.10.096.
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Ivankovic, D;
Drew, J;
Lesept, F;
White, IJ;
López Doménech, G;
Tooze, SA;
Kittler, JT;
(2019)
Axonal autophagosome maturation defect through failure of ATG9A sorting underpins pathology in AP-4 deficiency syndrome.
Autophagy
10.1080/15548627.2019.1615302.
(In press).
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Jovanovic, JN;
Thomas, P;
Kittler, JT;
Smart, TG;
Moss, SJ;
(2004)
Brain-derived neurotrophic factor modulates fast synaptic inhibition by regulating GABA(A) receptor phosphorylation, activity, and cell-surface stability.
J NEUROSCI
, 24
(2)
522 - 530.
10.1523/JNEUROSCI.3606-03.2004.
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Kittler, JT;
Delmas, P;
Jovanovic, JN;
Brown, DA;
Smart, TG;
Moss, SJ;
(2000)
Constitutive endocytosis of GABA(A) receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons.
J NEUROSCI
, 20
(21)
7972 - 7977.
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Klionsky, DJ;
Abdel-Aziz, AK;
Abdelfatah, S;
Abdellatif, M;
Abdoli, A;
Abel, S;
Abeliovich, H;
... Taylor, A; + view all
(2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Autophagy
, 17
(1)
pp. 1-382.
10.1080/15548627.2020.1797280.
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Kontou, G;
Antonoudiou, P;
Podpolny, M;
Szulc, BR;
Arancibia-Carcamo, IL;
Higgs, NF;
Lopez-Domenech, G;
... Kittler, JT; + view all
(2021)
Miro1-dependent mitochondrial dynamics in parvalbumin Interneurons.
eLife
10.7554/eLife.65215.
(In press).
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Kontou, G;
Josephine Ng, SF;
Cardarelli, RA;
Howden, JH;
Choi, C;
Ren, Q;
Rodriguez Santos, MA;
... Smalley, JL; + view all
(2021)
KCC2 is required for the survival of mature neurons but not for their development.
Journal of Biological Chemistry
, Article 100364. 10.1016/j.jbc.2021.100364.
(In press).
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López-Doménech, Guillermo;
Kittler, Josef T;
(2023)
Mitochondrial regulation of local supply of energy in neurons.
Current Opinion in Neurobiology
, 81
, Article 102747. 10.1016/j.conb.2023.102747.
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López-Doménech, G;
Covill-Cooke, C;
Ivankovic, D;
Halff, EF;
Sheehan, DF;
Norkett, R;
Birsa, N;
(2018)
Miro proteins coordinate microtubule- and actin-dependent mitochondrial transport and distribution.
The EMBO Journal
, Article e96380. 10.15252/embj.201696380.
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Lopez-Domenech, G;
Higgs, NF;
Vaccaro, V;
Ros, H;
Arancibia-Carcamo, IL;
MacAskill, AF;
Kittler, JT;
(2016)
Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites.
Cell Reports
, 17
(2)
pp. 317-327.
10.1016/j.celrep.2016.09.004.
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López-Doménech, G;
Howden, JH;
Covill-Cooke, C;
Morfill, C;
Patel, JV;
Bürli, R;
Crowther, D;
... Kittler, JT; + view all
(2021)
Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response.
The EMBO Journal
, Article e100715. 10.15252/embj.2018100715.
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Modi, S;
Higgs, NF;
Sheehan, D;
Griffin, LD;
Kittler, JT;
(2018)
Quantum dot conjugated nanobodies for multiplex imaging of protein dynamics at synapses.
Nanoscale
, 10
(21)
pp. 10241-10249.
10.1039/c7nr09130c.
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Modi, S;
López-Doménech, G;
Halff, EF;
Covill-Cooke, C;
Ivankovic, D;
Melandri, D;
Arancibia-Cárcamo, IL;
... Kittler, JT; + view all
(2019)
Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery.
Nature Communications
, 10
, Article 4399. 10.1038/s41467-019-12382-4.
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Muir, J;
Kittler, JT;
(2014)
Plasticity of GABAA receptor diffusion dynamics at the axon initial segment.
Front Cell Neurosci
, 8
, Article e1001510. 10.3389/fncel.2014.00151.
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Nadappuram, BP;
Cadinu, P;
Barik, A;
Ainscough, AJ;
Devine, MJ;
Kang, M;
Gonzalez-Garcia, J;
... Edel, JB; + view all
(2019)
Nanoscale tweezers for single-cell biopsies.
Nature Nanotechnology
, 14
pp. 80-88.
10.1038/s41565-018-0315-8.
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Norkett, R;
Lesept, F;
Kittler, JT;
(2020)
DISC1 Regulates Mitochondrial Trafficking in a Miro1-GTP-Dependent Manner.
Frontiers in Cell and Developmental Biology
, 8
, Article 449. 10.3389/fcell.2020.00449.
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Norkett, R;
Modi, S;
Birsa, N;
Atkin, TA;
Ivankovic, D;
Pathania, M;
Trossbach, SV;
... Kittler, JT; + view all
(2016)
DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites.
Journal of Biological Chemistry
, 291
(2)
pp. 613-629.
10.1074/jbc.M115.699447.
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Norkett, R;
Modi, S;
Kittler, JT;
(2017)
Mitochondrial roles of the psychiatric disease risk factor DISC1.
Schizophrenia Research
, 187
pp. 47-54.
10.1016/j.schres.2016.12.025.
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Novak, J;
Nahacka, Z;
Oliveira, GL;
Brisudova, P;
Dubisova, M;
Dvorakova, S;
Miklovicova, S;
... Neuzil, J; + view all
(2025)
The adaptor protein Miro1 modulates horizontal transfer of mitochondria in mouse melanoma models.
Cell Reports
, 44
(1)
, Article 115154. 10.1016/j.celrep.2024.115154.
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Pathania, M;
Davenport, EC;
Muir, J;
Sheehan, DF;
López-Doménech, G;
Kittler, JT;
(2014)
The autism and schizophrenia associated gene CYFIP1 is critical for the maintenance of dendritic complexity and the stabilization of mature spines.
Transl Psychiatry
, 4
, Article e374. 10.1038/tp.2014.16.
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Smith, KR;
Davenport, EC;
Wei, J;
Li, X;
Pathania, M;
Vaccaro, V;
Yan, Z;
(2014)
GIT1 and βPIX are essential for GABA(A) receptor synaptic stability and inhibitory neurotransmission.
Cell Rep
, 9
(1)
298 - 310.
10.1016/j.celrep.2014.08.061.
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Stephen, TL;
Gupta-Agarwal, S;
Kittler, JT;
(2014)
Mitochondrial dynamics in astrocytes.
Biochem Soc Trans
, 42
(5)
1302 - 1310.
10.1042/BST20140195.
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Stephen, TL;
Higgs, NF;
Sheehan, DF;
Al Awabdh, S;
López-Doménech, G;
Arancibia-Carcamo, IL;
Kittler, JT;
(2015)
Miro1 Regulates Activity-Driven Positioning of Mitochondria within Astrocytic Processes Apposed to Synapses to Regulate Intracellular Calcium Signaling.
Journal of Neuroscience
, 35
(48)
pp. 15996-16011.
10.1523/JNEUROSCI.2068-15.2015.
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Terunuma, M;
Jang, IS;
Ha, SH;
Kittler, JT;
Kanematsu, T;
Jovanovic, JN;
Nakayama, KI;
... Hirata, M; + view all
(2004)
GABA(A) receptor phospho-dependent modulation is regulated by phospholipase C-related inactive protein type 1, a novel protein phosphatase 1 anchoring protein.
J NEUROSCI
, 24
(32)
7074 - 7084.
10.1523/JNEUROSCI.1323-04.2004.
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Twelvetrees, AE;
Lesept, F;
Holzbaur, ELF;
Kittler, JT;
(2019)
The adaptor proteins HAP1a and GRIP1 collaborate to activate kinesin-1 isoform KIF5C.
Journal of Cell Science
, 132
, Article jcs215822. 10.1242/jcs.215822.
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Vaccaro, V;
Devine, MJ;
Higgs, NF;
Kittler, JT;
(2017)
Miro1-dependent mitochondrial positioning drives the rescaling of presynaptic Ca2+ signals during homeostatic plasticity.
EMBO Reports
, 18
(2)
pp. 231-240.
10.15252/embr.201642710.
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Verinaz-Jadan, H;
Howe, CL;
Song, P;
Lesept, F;
Kittler, J;
Foust, AJ;
Dragotti, PL;
(2023)
Physics-Based Deep Learning for Imaging Neuronal Activity via Two-Photon and Light Field Microscopy.
IEEE Transactions on Computational Imaging
, 9
pp. 565-580.
10.1109/TCI.2023.3282052.
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Thesis
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Davenport, EC;
(2016)
The autism and schizophrenia associated genes CYFIP1 and Ahi1 in synaptic signalling and neuronal development.
Doctoral thesis , UCL (University College London).
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Eckel, R;
(2015)
The Trafficking of GABAARs During Prolonged Seizure Activity.
Doctoral thesis , UCL (University College London).
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Kontou, Georgina;
(2018)
Miro1-dependent Mitochondrial Dynamics in Parvalbumin Interneurons.
Doctoral thesis (Ph.D), UCL (University College London).
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Norkett, R;
(2016)
Contribution of the schizophrenia associated protein DISC1 to Mitochondrial Dynamics and Dendritic Development.
Doctoral thesis , UCL (University College London).
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