Browse by UCL people
Group by: Type | Date
Number of items: 60.
Article
Albert, Michael H;
Sirait, Tiarlan;
Eikema, Dirk-Jan;
Bakunina, Katerina;
Wehr, Claudia;
Suarez, Felipe;
Fox, María Laura;
... Morris, Emma C; + view all
(2022)
Hematopoietic stem cell transplantation for adolescents and adults with inborn errors of immunity, an EBMT IEWP study.
Blood
, 140
(14)
pp. 1635-1649.
10.1182/blood.2022015506.
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Albuquerque, Adriana S;
Maimaris, Jesmeen;
McKenna, Alexander J;
Lambourne, Jonathan;
Moreira, Fernando;
Workman, Sarita;
Megy, Karyn;
... Burns, Siobhan O; + view all
(2023)
Practical challenges for functional validation of STAT1 gain of function genetic variants.
Clinical & Experimental Immunology
, 212
(2)
pp. 166-169.
10.1093/cei/uxad008.
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Anantharachagan, A;
Loh, SY;
Burns, SO;
Laurence, A;
Tadros, S;
Tholouli, E;
Lwin, Y;
... Morris, EC; + view all
(2024)
Allogeneic hematopoietic stem cell transplantation outcome in oldest known surviving patients with Wiskott-Aldrich syndrome.
Journal of Allergy and Clinical Immunology: Global
, 3
(1)
, Article 100191. 10.1016/j.jacig.2023.100191.
(In press).
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Arnold, Danielle E;
Nofal, Rofida;
Wakefield, Connor;
Lehmberg, Kai;
Wustrau, Katharina;
Albert, Michael H;
Morris, Emma C;
... Marsh, Rebecca A; + view all
(2022)
Reduced-Intensity/Reduced-Toxicity Conditioning Approaches Are Tolerated in XIAP Deficiency but Patients Fare Poorly with Acute GVHD.
Journal of Clinical Immunology
, 42
(1)
pp. 36-45.
10.1007/s10875-021-01103-6.
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Bahal, Sameer;
Zinicola, Marta;
Moula, Shefta E;
Whittaker, Thomas E;
Schejtman, Andrea;
Naseem, Asma;
Blanco, Elena;
... Santilli, Giorgia; + view all
(2024)
Hematopoietic stem cell gene editing rescues B cell development in X-linked agammaglobulinemia.
Journal of Allergy and Clinical Immunology
10.1016/j.jaci.2024.03.003.
(In press).
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Burns, S;
Morris, EC;
(2021)
How I use allogeneic HSCT for adults with inborn errors of immunity.
Blood
, 138
(18)
pp. 1666-1676.
10.1182/blood.2020008187.
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Cheminant, Morgane;
Fox, Thomas A;
Alligon, Mickael;
Bouaziz, Olivier;
Neven, Bénédicte;
Moshous, Despina;
Blanche, Stephane;
... Suarez, Felipe; + view all
(2023)
Allogeneic stem cell transplantation compared to conservative management in adults with inborn errors of immunity.
Blood
, 141
(1)
pp. 60-71.
10.1182/blood.2022015482.
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Chen, Y;
Ayaru, L;
Mathew, S;
Morris, E;
Pereira, SP;
Behboudi, S;
(2014)
Expansion of Anti-Mesothelin Specific CD4(+) and CD8(+) T Cell Responses in Patients with Pancreatic Carcinoma.
PLoS One
, 9
(2)
, Article e88133. 10.1371/journal.pone.0088133.
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Chen, Y;
Xue, S-A;
Behboudi, S;
Mohammad, GH;
Pereira, SP;
Morris, EC;
(2017)
Ex Vivo PD-L1/PD-1 Pathway Blockade Reverses Dysfunction of Circulating CEA-Specific T Cells in Pancreatic Cancer Patients.
Clinical Cancer Research
, 23
(20)
pp. 6178-6189.
10.1158/1078-0432.CCR-17-1185.
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Cuadrado, MM;
Szydlo, RM;
Watts, M;
Patel, N;
Renshaw, H;
Dorman, J;
Lowdell, M;
... Chakraverty, R; + view all
(2019)
Predictors of recovery following allogeneic CD34+-selected cell infusion without conditioning to correct poor graft function.
Haematologica
, 105
(11)
10.3324/haematol.2019.226340.
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Day, James W;
Elfeky, Reem;
Nicholson, Bethany;
Goodman, Rupert;
Pearce, Rachel;
Fox, Thomas A;
Worth, Austen;
... Morris, Emma C; + view all
(2022)
Retrospective, Landmark Analysis of Long-term Adult Morbidity Following Allogeneic HSCT for Inborn Errors of Immunity in Infancy and Childhood.
Journal of Clinical Immunology
10.1007/s10875-022-01278-6.
(In press).
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Degirmencay, Abdullah;
Thomas, Sharyn;
Holler, Angelika;
Burgess, Samuel;
Morris, Emma C;
Stauss, Hans J;
(2024)
Exploitation of CD3ζ to enhance TCR expression levels and antigen-specific T cell function.
Frontiers in Immunology
, 15
, Article 1386132. 10.3389/fimmu.2024.1386132.
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Dimitrova, D;
Nademi, Z;
Maccari, ME;
Ehl, S;
Uzel, G;
Tomoda, T;
Okano, T;
... Kanakry, JA; + view all
(2021)
International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome.
Journal of Allergy and Clinical Immunology
10.1016/j.jaci.2021.04.036.
(In press).
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Donnadieu, Emmanuel;
Luu, Maik;
Alb, Miriam;
Anliker, Brigitte;
Arcangeli, Silvia;
Bonini, Chiara;
De Angelis, Biagio;
... Casucci, Monica; + view all
(2022)
Time to evolve: predicting engineered T cell-associated toxicity with next-generation models.
Journal for ImmunoTherapy of Cancer
, 10
(5)
, Article e003486. 10.1136/jitc-2021-003486.
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Einsele, H;
Briones, J;
Ciceri, F;
García Cadenas, I;
Falkenburg, F;
Bolaños, N;
Heemskerk, HMM;
... van de Loosdrecht, AA; + view all
(2021)
The EHA Research Roadmap: Immune-based Therapies for Hematological Malignancies.
Hemasphere
, 5
(10)
, Article e642. 10.1097/HS9.0000000000000642.
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Field, AC;
Vink, C;
Gabriel, R;
Al-Subki, R;
Schmidt, M;
Goulden, N;
Stauss, H;
... Qasim, W; + view all
(2013)
Comparison of Lentiviral and Sleeping Beauty Mediated αβ T Cell Receptor Gene Transfer.
PLoS One
, 8
(6)
, Article e68201. 10.1371/journal.pone.0068201.
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Fox, TA;
Kirkwood, AA;
Enfield, L;
O'Reilly, M;
Arulogun, S;
D'Sa, S;
O'Nions, J;
... Morris, EC; + view all
(2021)
Low seropositivity and suboptimal neutralisation rates in patients fully vaccinated against COVID-19 with B-cell malignancies.
British Journal of Haematology
, 195
(5)
pp. 706-709.
10.1111/bjh.17836.
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Fox, TA;
Troy-Barnes, E;
Kirkwood, AA;
Chan, WY;
Day, JW;
Chavda, SJ;
Kumar, EA;
... Ardeshna, KM; + view all
(2020)
Response to 'Impact of immunosuppression on mortality in critically ill COVID-19 patients'.
British Journal of Haematology
, 191
(3)
pp. 505-506.
10.1111/bjh.17110.
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Fox, Thomas A;
Massey, Valerie;
Lever, Charley;
Pearce, Rachel;
Laurence, Arian;
Grace, Sarah;
Oliviero, Filippo;
... Morris, Emma C; + view all
(2025)
Pre-Transplant Immune Dysregulation Predicts for Poor Outcome Following Allogeneic Haematopoietic Stem Cell Transplantation in Adolescents and Adults with Inborn Errors of Immunity (IEI).
Journal of Clinical Immunology
, 45
, Article 64. 10.1007/s10875-024-01854-y.
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Fox, Thomas Andrew;
Houghton, Benjamin Christopher;
Petersone, Lina;
Waters, Erin;
Edner, Natalie Mona;
McKenna, Alex;
Preham, Olivier;
... Morris, Emma Catherine; + view all
(2022)
Therapeutic gene editing of T cells to correct CTLA-4 insufficiency.
Science Translational Medicine
, 14
(668)
, Article eabn5811. 10.1126/scitranslmed.abn5811.
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Fox, T;
Chakraverty, R;
Burns, S;
Carpenter, B;
Thomson, K;
Lowe, D;
Fielding, A;
... Morris, EC; + view all
(2018)
Successful outcome following allogeneic hematopoietic stem cell transplantation in adults with primary immunodeficiency.
Blood
, 131
(8)
pp. 917-931.
10.1182/blood-2017-09-807487.
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Fox, TA;
Troy-Barnes, E;
Kirkwood, AA;
Chan, WY;
Day, J;
Chavda, SJ;
Kumar, EA;
... Ardeshna, KM; + view all
(2020)
Clinical outcomes and risk factors for severe COVID‐19 infection in patients with haematological disorders receiving chemo‐ or immunotherapy.
British Journal of Haematology
, 191
(2)
pp. 194-206.
10.1111/bjh.17027.
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Ghorashian, S;
Veliça, P;
Chua, I;
McNicol, AM;
Carpenter, B;
Holler, A;
Nicholson, E;
... Stauss, HJ; + view all
(2015)
CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor.
Journal of Immunology
, 194
(3)
1080 - 1089.
10.4049/jimmunol.1401703.
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Ghosh, S;
Köstel Bal, S;
Edwards, ESJ;
Pillay, B;
Jimenez-Heredia, R;
Rao, G;
Erol Cipe, F;
... Boztug, K; + view all
(2020)
Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency.
Blood
, 136
(23)
pp. 2638-2655.
10.1182/blood.2020006738.
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Gohil, SH;
Paredes-Moscosso, SR;
Harrasser, M;
Vezzalini, M;
Scarpa, A;
Morris, E;
Davidoff, AM;
... Della Peruta, M; + view all
(2017)
An ROR1 bi-specific T-cell engager provides effective targeting and cytotoxicity against a range of solid tumors.
OncoImmunology
, 6
(7)
, Article e1326437. 10.1080/2162402X.2017.1326437.
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Golwala, Zainab M;
Bhat, Nikita Gireesh;
Xu-Bayford, Jinhua;
Stankova, Tanja;
Adams, Stuart;
Morris, Emma C;
Qasim, Waseem;
... Elfeky, Reem; + view all
(2023)
Non-osteopenic Bone Pathology After Allo-hematopoietic Stem Cell Transplantation in Patients with Inborn Errors of Immunity.
Journal of Clinical Immunology
10.1007/s10875-023-01465-z.
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Guedan, Sonia;
Luu, Maik;
Ammar, Delphine;
Barbao, Paula;
Bonini, Chiara;
Bousso, Philippe;
Buchholz, Christian J;
... Marchiq, Ibtissam; + view all
(2022)
Time 2EVOLVE: predicting efficacy of engineered T-cells - how far is the bench from the bedside?
Journal for ImmunoTherapy of Cancer
, 10
(5)
, Article e003487. 10.1136/jitc-2021-003487.
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Hamblin, A;
Greenfield, DM;
Gilleece, M;
Salooja, N;
Kenyon, M;
Morris, E;
Glover, N;
... Snowden, JA; + view all
(2017)
Provision of long-term monitoring and late effects services following adult allogeneic haematopoietic stem cell transplant: a survey of UK NHS-based programmes.
Bone Marrow Transplantation
, 52
(6)
pp. 889-894.
10.1038/bmt.2017.67.
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Holler, A;
Zech, M;
Ghorashian, S;
Pike, R;
Hotblack, A;
Velica, P;
Xue, S-A;
... Stauss, HJ; + view all
(2016)
Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy.
Haematologica
, 101
(4)
pp. 482-490.
10.3324/haematol.2015.132712.
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Kennedy, Alan;
Waters, Erin;
Rowshanravan, Behzad;
Hinze, Claudia;
Williams, Cayman;
Janman, Daniel;
Fox, Thomas A;
... Sansom, David M; + view all
(2022)
Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation.
Nature Immunology
10.1038/s41590-022-01289-w.
(In press).
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Khan, AB;
Carpenter, B;
Sousa, PSE;
Pospori, C;
Khorshed, R;
Griffin, J;
Veliça, P;
... Chakraverty, R; + view all
(2018)
Redirection to the bone marrow improves T cell persistence and antitumor functions.
The Journal of Clinical Investigation
, 128
(5)
pp. 2010-2024.
10.1172/JCI97454.
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Kohn, DB;
Booth, C;
Kang, EM;
Pai, S-Y;
Shaw, KL;
Santilli, G;
Armant, M;
... the Net4CGD consortium; + view all
(2020)
Lentiviral gene therapy for X-linked chronic granulomatous disease.
Nature Medicine
, 26
pp. 200-206.
10.1038/s41591-019-0735-5.
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Kozyra, EJ;
Pastor, VB;
Lefkopoulos, S;
Sahoo, SS;
Busch, H;
Voss, RK;
Erlacher, M;
... Wlodarski, MW; + view all
(2020)
SynonymousGATA2mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency.
Leukemia
10.1038/s41375-020-0899-5.
(In press).
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Lankester, AC;
Albert, MH;
Booth, C;
Gennery, AR;
Güngör, T;
Hönig, M;
Morris, EC;
... Inborn Errors Working Party of the European Society for Blood an; + view all
(2021)
EBMT/ESID inborn errors working party guidelines for hematopoietic stem cell transplantation for inborn errors of immunity.
Bone Marrow Transplant
10.1038/s41409-021-01378-8.
(In press).
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Leiper, A;
Houwing, M;
Davies, EG;
Rao, K;
Burns, S;
Morris, E;
Laven, J;
... Nussey, S; + view all
(2020)
Anti-Mullerian hormone and Inhibin B after stem cell transplant in childhood: a comparison of myeloablative, reduced intensity and treosulfan-based chemotherapy regimens.
Bone Marrow Transplantation
10.1038/s41409-020-0866-9.
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Magnani, A;
Semeraro, M;
Adam, F;
Booth, C;
Dupré, L;
Morris, EC;
Gabrion, A;
... Cavazzana, M; + view all
(2022)
Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott–Aldrich syndrome.
nature medicine
, 28
pp. 71-80.
10.1038/s41591-021-01641-x.
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Marzolini, Maria AV;
Kayani, Irfan;
Carpenter, Ben;
Laurence, Arian;
McLornan, Donal;
Raj, Kavita;
O'Reilly, Maeve;
... Peggs, Karl S; + view all
(2024)
The Effect of the Pre-Transplant Disease Status on the Outcome for Recipients of T-Cell Depleted Allogeneic Haematopoietic Stem Cell Transplants for Large B Cell Lymphomas.
European Journal of Haematology
10.1111/ejh.14361.
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Marzolini, MAV;
Wilson, AJ;
Sanchez, E;
Carpenter, B;
Chakraverty, R;
Hough, R;
Kottaridis, P;
... Peggs, KS; + view all
(2021)
Natural History of Epstein-Barr Virus Replication and Viral Load Dynamics after Alemtuzumab-Based Allogeneic Stem Cell Transplantation.
Transplantation and Cellular Therapy
, 27
(8)
682.e1-682.e12.
10.1016/j.jtct.2021.04.020.
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Morris, EC;
(2020)
HCT for CGD? Yes, and the sooner the better.
Blood
, 136
(10)
pp. 1121-1123.
10.1182/blood.2020007891.
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Morris, EC;
Neelapu, SS;
Giavridis, T;
Sadelain, M;
(2022)
Cytokine release syndrome and associated neurotoxicity in cancer immunotherapy.
Nature Reviews Immunology
, 22
pp. 85-96.
10.1038/s41577-021-00547-6.
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Morris, E.;
Thomson, K.;
Craddock, C.;
Mahendra, P.;
Milligan, D.;
Cook, G.;
Smith, G.M.;
... Mackinnon, S.; + view all
(2004)
Outcomes after alemtuzumab-containing reduced-intensity allogeneic transplantation regimen for relapsed and refractory non-Hodgkin lymphoma.
Blood
, 104
(13)
pp. 3865-3871.
10.1182/blood-2004-03-1105.
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Morris, EC;
(2020)
Allogeneic hematopoietic stem cell transplantation in adults with primary immunodeficiency.
Hematology
(1)
pp. 649-660.
10.1182/hematology.2020000152.
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Morris, EC;
(2020)
Engineered T cells Flt around their targets.
Nature Immunology
, 21
pp. 831-832.
10.1038/s41590-020-0740-3.
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Morris, EC;
(2018)
Editing gene engineering to enhance function.
Blood
, 131
(3)
pp. 272-273.
10.1182/blood-2017-11-816587.
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Morris, EC;
Albert, MH;
(2019)
Allogeneic HSCT in Adolescents and Young Adults With Primary Immunodeficiencies.
Frontiers in Pediatrics
, 7
, Article 437. 10.3389/fped.2019.00437.
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Morris, EC;
Fox, T;
Chakraverty, R;
Tendeiro, R;
Snell, K;
Rivat, C;
Grace, S;
... Thrasher, AJ; + view all
(2017)
Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult.
Blood
, 130
pp. 1327-1335.
10.1182/blood-2017-04-777136.
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Nicholson, Bethany;
Goodman, Rupert;
Day, James;
Worth, Austen;
Carpenter, Ben;
Sandford, Kit;
Morris, Emma C;
... Campbell, Mari; + view all
(2022)
Quality of Life and Social and Psychological Outcomes in Adulthood Following Allogeneic HSCT in Childhood for Inborn Errors of Immunity.
Journal of Clinical Immunology
10.1007/s10875-022-01286-6.
(In press).
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Rego, RT;
Morris, EC;
Lowdell, MW;
(2019)
T-cell receptor gene-modified cells: past promises, present methodologies and future challenges.
Cytotherapy
, 21
(3)
pp. 341-357.
10.1016/j.jcyt.2018.12.002.
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Reyal, Y;
Kayani, I;
Bloor, AJC;
Fox, CP;
Chakraverty, R;
Sjursen, A-M;
Fielding, AK;
... Peggs, KS; + view all
(2016)
Impact of Pretransplantation F-18-Fluorodeoxyglucose-Positron Emission Tomography on Survival Outcomes after T Cell-Depleted Allogeneic Transplantation for Hodgkin Lymphoma.
Biology of Blood and Marrow Transplantation
, 22
(7)
pp. 1234-1241.
10.1016/j.bbmt.2016.03.034.
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Schuetz, Catharina;
Gerke, Julia;
Ege, Markus Johannes;
Walter, Jolan Eszter;
Kusters, Maaike;
Worth, Austen JJ;
Kanakry, Jennifer A;
... Neven, Bénédicte; + view all
(2023)
Hypomorphic RAG deficiency: impact of disease burden on survival and thymic recovery argues for early diagnosis and HSCT.
Blood
, 141
(7)
pp. 713-724.
10.1182/blood.2022017667.
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Sellar, RS;
Mehra, V;
Fox, TA;
Grigg, A;
Kulasekararaj, A;
Sarma, A;
de Lavallade, H;
... Potter, VT; + view all
(2019)
Comparative analysis of melphalan versus busulphan T-cell deplete conditioning using alemtuzumab in unrelated donor stem cell transplantation for acute myeloid leukaemia.
British Journal of Haematology
, 187
(1)
e20-e24.
10.1111/bjh.16136.
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Sharma, Mehul;
Leung, Daniel;
Momenilandi, Mana;
Jones, Lauren CW;
Pacillo, Lucia;
James, Alyssa E;
Murrell, Jill R;
... Turvey, Stuart E; + view all
(2023)
Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease.
Journal of Experimental Medicine
, 220
(5)
, Article e20221755. 10.1084/jem.20221755.
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Steele, CL;
Dore, M;
Ammann, S;
Loughrey, M;
Montero, A;
Burns, SO;
Morris, EC;
... Edgar, DM; + view all
(2016)
X-linked Inhibitor of Apoptosis Complicated by Granulomatous Lymphocytic Interstitial Lung Disease (GLILD) and Granulomatous Hepatitis.
Journal of Clinical Immunology
, 36
(7)
pp. 733-738.
10.1007/s10875-016-0320-3.
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Thomas, S;
Mohammed, F;
Reijmers, RM;
Woolston, A;
Stauss, T;
Kennedy, A;
Stirling, D;
... Stauss, HJ; + view all
(2019)
Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function.
Nature Communications
, 10
(1)
, Article 4451. 10.1038/s41467-019-12441-w.
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Townsend, WM;
Holroyd, A;
Pearce, R;
Mackinnon, S;
Naik, P;
Goldstone, AH;
Linch, DC;
... Morris, EC; + view all
(2013)
Improved intensive care unit survival for critically ill allogeneic haematopoietic stem cell transplant recipients following reduced intensity conditioning.
Br J Haematol
, 161
(4)
578 - 586.
10.1111/bjh.12294.
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Uttenthal, B;
Martinez-Davila, I;
Ivey, A;
Craddock, C;
Chen, F;
Virchis, A;
Kottaridis, P;
... Morris, EC; + view all
(2014)
Wilms' Tumour 1 (WT1) peptide vaccination in patients with acute myeloid leukaemia induces short-lived WT1-specific immune responses.
Br J Haematol
, 164
(3)
366 - 375.
10.1111/bjh.12637.
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Yang, L;
Booth, C;
Speckmann, C;
Seidel, MG;
Worth, AJ;
Kindle, G;
Lankester, AC;
... Burns, SO; + view all
(2022)
Phenotype, genotype, treatment, and survival outcomes in patients with X-linked inhibitor of apoptosis deficiency.
Journal of Allergy and Clinical Immunology
, 150
(2)
pp. 456-466.
10.1016/j.jaci.2021.10.037.
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Book chapter
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Fox, T;
Booth, C;
Morris, E;
(2021)
Gene Therapy in Cellular Immunodeficiencies.
In:
Cellular Primary Immunodeficiencies.
(pp. 473-497).
Springer
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Conference item
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Morris, EC;
Tendeiro-Rego, R;
Richardson, R;
Fox, TA;
Sillito, F;
Holler, A;
Thomas, S;
... Stauss, H; + view all
(2019)
A Phase I Study Evaluating the Safety and Persistence of Allorestricted WT1-TCR Gene Modified Autologous T Cells in Patients with High-Risk Myeloid Malignancies Unsuitable for Allogeneic Stem Cell Transplantation.
Presented at: 61st ASH Annual Meeting, Orlando, FL, USA.
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Thesis
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Kolluri, KK;
(2016)
Synergistic treatment of lung cancer with genetically modified cell therapy and chemotherapy.
Doctoral thesis , UCL (University College London).
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