Browse by UCL people
Group by: Type | Date
Number of items: 41.
Article
Abbosh, Christopher;
Frankell, Alexander M;
Harrison, Thomas;
Kisistok, Judit;
Garnett, Aaron;
Johnson, Laura;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2023)
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Nature
, 616
(7957)
pp. 553-562.
10.1038/s41586-023-05776-4.
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Abbosh, C;
Birkbak, NJ;
Wilson, GA;
Jamal-Hanjani, M;
Constantin, T;
Salari, R;
Le Quesne, J;
... Dessimoz, C; + view all
(2017)
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
Nature
, 545
pp. 446-451.
10.1038/nature22364.
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AbdulJabbar, K;
Raza, SEA;
Rosenthal, R;
Jamal-Hanjani, M;
Veeriah, S;
Akarca, A;
Lund, T;
... Yuan, Y; + view all
(2020)
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma.
Nature Medicine
, 26
pp. 1054-1062.
10.1038/s41591-020-0900-x.
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Au, L;
Hatipoglu, E;
Robert de Massy, M;
Litchfield, K;
Beattie, G;
Rowan, A;
Schnidrig, D;
... TRACERx Renal Consortium; + view all
(2021)
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.
Cancer Cell
, 39
pp. 1497-1518.
10.1016/j.ccell.2021.10.001.
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Banfill, K;
Croxford, W;
Fornacon-Wood, I;
Wicks, K;
Ahmad, S;
Britten, A;
Carson, C;
... Faivre-Finn, C; + view all
(2021)
Changes in the Management of Patients having Radical Radiotherapy for Lung Cancer during the First Wave of the COVID-19 Pandemic in the UK.
Clinical Oncology
10.1016/j.clon.2021.10.009.
(In press).
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Bentham, R;
Litchfield, K;
Watkins, TBK;
Lim, EL;
Rosenthal, R;
Martinez-Ruiz, C;
Hiley, CT;
... McGranahan, N; + view all
(2021)
Using DNA sequencing data to quantify T cell fraction and therapy response.
Nature
, 597
pp. 555-560.
10.1038/s41586-021-03894-5.
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Biswas, D;
Birkbak, NJ;
Rosenthal, R;
Hiley, CT;
Lim, EL;
Papp, K;
Boeing, S;
... TRACERx Consortium; + view all
(2019)
A clonal expression biomarker associates with lung cancer mortality.
Nature Medicine
, 25
pp. 1540-1548.
10.1038/s41591-019-0595-z.
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Chemi, F;
Rothwell, DG;
McGranahan, N;
Gulati, S;
Abbosh, C;
Pearce, SP;
Zhou, C;
... TRACERx Consortium, .; + view all
(2019)
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.
Nature Medicine
, 25
pp. 1534-1539.
10.1038/s41591-019-0593-1.
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Ding, H;
Velasco, C;
Ye, H;
Lindner, T;
Grech-Sollars, M;
O'Callaghan, J;
Hiley, C;
... Adeleke, S; + view all
(2021)
Current Applications and Future Development of Magnetic Resonance Fingerprinting in Diagnosis, Characterization, and Response Monitoring in Cancer.
Cancers
, 13
(19)
, Article 4742. 10.3390/cancers13194742.
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El Bairi, K;
Haynes, HR;
Blackley, E;
Fineberg, S;
Shear, J;
Turner, S;
de Freitas, JR;
... Bautista, V; + view all
(2021)
The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group.
npj Breast Cancer
, 7
, Article 150. 10.1038/s41523-021-00346-1.
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Enfield, Katey SS;
Colliver, Emma;
Lee, Claudia SY;
Magness, Alastair;
Moore, David A;
Sivakumar, Monica;
Grigoriadis, Kristiana;
... Angelova, Mihaela; + view all
(2024)
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer.
Cancer Discovery
, 14
(1)
pp. 1-30.
10.1158/2159-8290.CD-23-1380.
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Evison, M;
Barrett, E;
Cheng, A;
Mulla, A;
Walls, G;
Johnston, D;
McAleese, J;
... Faivre-Finn, C; + view all
(2021)
Predicting the Risk of Disease Recurrence and Death Following Curative-intent Radiotherapy for Non-small Cell Lung Cancer: The Development and Validation of Two Scoring Systems From a Large Multicentre UK Cohort.
Clinical Oncology
, 33
(3)
pp. 145-154.
10.1016/j.clon.2020.09.001.
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Faivre-Finn, C;
Fenwick, JD;
Franks, KN;
Harrow, S;
Hatton, MQF;
Hiley, C;
McAleese, JJ;
... Toy, E; + view all
(2020)
Reduced Fractionation in Lung Cancer Patients Treated with Curative-intent Radiotherapy during the COVID-19 Pandemic.
Clinical Oncology
, 32
(8)
pp. 481-489.
10.1016/j.clon.2020.05.001.
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Ferguson, MS;
Chard Dunmall, LS;
Gangeswaran, R;
Marelli, G;
Tysome, JR;
Burns, E;
Whitehead, MA;
... Wang, Y; + view all
(2020)
Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus.
Molecular Therapy
10.1016/j.ymthe.2020.02.017.
(In press).
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Frankell, Alexander M;
Dietzen, Michelle;
Al Bakir, Maise;
Lim, Emilia L;
Karasaki, Takahiro;
Ward, Sophia;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2024)
The evolution of lung cancer and impact of subclonal selection in TRACERx (vol 616, pg 525, 2023).
[Corrigendum].
Nature
, 631
, Article E15. 10.1038/s41586-024-07738-w.
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Frankell, AM;
Dietzen, M;
Al Bakir, M;
Lim, EL;
Karasaki, T;
Ward, S;
Veeriah, S;
... Gilbert, K; + view all
(2023)
The evolution of lung cancer and impact of subclonal selection in TRACERx.
Nature
, 616
pp. 525-533.
10.1038/s41586-023-05783-5.
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Ghorani, E;
Reading, JL;
Henry, JY;
Massy, MRD;
Rosenthal, R;
Turati, V;
Joshi, K;
... Quezada, SA; + view all
(2020)
The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
Nature Cancer
, 1
(5)
pp. 546-561.
10.1038/s43018-020-0066-y.
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Hiley, C;
Salem, A;
Batchelor, T;
McDonald, F;
Evison, M;
(2020)
Great debate: surgery versus stereotactic radiotherapy for early-stage non-small cell lung cancer.
Thorax
, 75
(3)
pp. 198-199.
10.1136/thoraxjnl-2019-214014.
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Hiley, CT;
Le Quesne, J;
Santis, G;
Sharpe, R;
De Castro, DG;
Middleton, G;
Swanton, C;
(2016)
Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease.
The Lancet
, 388
(10048)
pp. 1002-1011.
10.1016/S0140-6736(16)31340-X.
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Hobor, S;
Al Bakir, M;
Hiley, CT;
Skrzypski, M;
Frankell, AM;
Bakker, B;
Watkins, TBK;
... Clipson, A; + view all
(2024)
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling.
Nature Communications
, 15
, Article 4871. 10.1038/s41467-024-47606-9.
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Hudeček, J;
Voorwerk, L;
van Seijen, M;
Nederlof, I;
de Maaker, M;
van den Berg, J;
van de Vijver, KK;
... Peale, F; + view all
(2020)
Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials.
npj Breast Cancer
, 6
, Article 15. 10.1038/s41523-020-0155-1.
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Hudson, A;
Chan, C;
Woolf, D;
McWilliam, A;
Hiley, C;
O'Connor, J;
Bayman, N;
... Faivre-Finn, C; + view all
(2018)
Is heterogeneity in stage 3 non-small cell lung cancer obscuring the potential benefits of dose-escalated concurrent chemo-radiotherapy in clinical trials?
Lung Cancer
, 118
pp. 139-147.
10.1016/j.lungcan.2018.02.006.
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Hynds, Robert E;
Huebner, Ariana;
Pearce, David R;
Hil, Mark S;
Akarca, Ayse U;
Moore, David A;
Ward, Sophia;
... Swanton, Charles; + view all
(2024)
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models.
Nature Communications
, 15
, Article 4653. 10.1038/s41467-024-47547-3.
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Jamal-Hanjani, M;
Wilson, GA;
McGranahan, N;
Birkbak, NJ;
Watkins, TBK;
Veeriah, S;
Shafi, S;
... Swanton, C; + view all
(2017)
Tracking the Evolution of Non-Small-Cell Lung Cancer.
New England Journal of Medicine
, 376
(22)
pp. 2109-2121.
10.1056/NEJMoa1616288.
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Joshi, K;
Robert de Massy, M;
Ismail, M;
Reading, JL;
Uddin, I;
Woolston, A;
Hatipoglu, E;
... Chain, B; + view all
(2019)
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Nature Medicine
, 25
pp. 1549-1559.
10.1038/s41591-019-0592-2.
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Kos, Z;
Roblin, E;
Kim, RS;
Michiels, S;
Gallas, BD;
Chen, W;
van de Vijver, KK;
... International Immuno-Oncology Biomarker Working Group; + view all
(2020)
Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer.
NPJ Breast Cancer
, 6
, Article 17. 10.1038/s41523-020-0156-0.
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Lieverse, RIY;
Van Limbergen, EJ;
Oberije, CJG;
Troost, EGC;
Hadrup, SR;
Dingemans, A-MC;
Hendriks, LEL;
... Lambin, P; + view all
(2020)
Stereotactic ablative body radiotherapy (SABR) combined with immunotherapy (L19-IL2) versus standard of care in stage IV NSCLC patients, ImmunoSABR: a multicentre, randomised controlled open-label phase II trial.
BMC Cancer
, 20
, Article 557. 10.1186/s12885-020-07055-1.
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Linch, M;
Goh, G;
Hiley, C;
Shanmugabavan, Y;
McGranahan, N;
Rowan, A;
Wong, YNS;
... Swanton, C; + view all
(2017)
Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters.
Annals of Oncology
, 28
(10)
pp. 2472-2480.
10.1093/annonc/mdx355.
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Litchfield, K;
Stanislaw, S;
Spain, L;
Gallegos, LL;
Rowan, A;
Schnidrig, D;
Rosenbaum, H;
... Turajlic, S; + view all
(2020)
Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue.
Cell Reports
, 31
(5)
p. 107550.
10.1016/j.celrep.2020.107550.
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López, S;
Lim, EL;
Horswell, S;
Haase, K;
Huebner, A;
Dietzen, M;
Mourikis, TP;
... McGranahan, N; + view all
(2020)
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
Nature Genetics
, 52
(3)
pp. 283-293.
10.1038/s41588-020-0584-7.
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Loveday, C;
Litchfield, K;
Proszek, PZ;
Cornish, AJ;
Santo, F;
Levy, M;
Macintyre, G;
... Turnbull, C; + view all
(2020)
Genomic landscape of platinum resistant and sensitive testicular cancers.
Nature Communications
, 11
, Article 2189. 10.1038/s41467-020-15768-x.
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McGranahan, N;
Rosenthal, R;
Hiley, CT;
Rowan, AJ;
Watkins, TBK;
Wilson, GA;
Birkbak, NJ;
... Swanton, C; + view all
(2017)
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.
Cell
10.1016/j.cell.2017.10.001.
(In press).
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Punjabi, A;
Barrett, E;
Cheng, A;
Mulla, A;
Walls, G;
Johnston, D;
McAleese, J;
... Evison, M; + view all
(2021)
Neutrophil-Lymphocyte Ratio and Absolute Lymphocyte Count as Prognostic Markers in Patients Treated with Curative-intent Radiotherapy for Non-small Cell Lung Cancer.
Clinical Oncology
, 33
(8)
e331-e338.
10.1016/j.clon.2021.03.019.
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Rosenthal, R;
Cadieux, EL;
Salgado, R;
Bakir, MA;
Moore, DA;
Hiley, CT;
Lund, T;
... TRACERx consortium; + view all
(2019)
Neoantigen-directed immune escape in lung cancer evolution.
Nature
10.1038/s41586-019-1032-7.
(In press).
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Round, T;
L'Esperance, V;
Bayly, J;
Brain, K;
Dallas, L;
Edwards, JG;
Haswell, T;
... Navani, N; + view all
(2021)
COVID-19 and the multidisciplinary care of patients with lung cancer: an evidence-based review and commentary.
British Journal of Cancer
, 125
pp. 629-640.
10.1038/s41416-021-01361-6.
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Shen, J;
Zhuang, W;
Xu, C;
Jin, K;
Chen, B;
Tian, D;
Hiley, C;
... Qiao, G; + view all
(2021)
Surgery or Non-surgical Treatment of <= 8 mm Non-small Cell Lung Cancer: A Population-Based Study.
Frontiers in Surgery
, 8
, Article ARTN 632. 10.3389/fsurg.2021.632561.
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Szmul, Adam;
Chandy, Edward;
Veiga, Catarina;
Jacob, Joseph;
Stavropoulou, Alkisti;
Landau, David;
Hiley, Crispin T;
(2022)
A Novel and Automated Approach to Classify Radiation Induced Lung Tissue Damage on CT Scans.
Cancers
, 14
(5)
, Article 1341. 10.3390/cancers14051341.
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Vargas, FA;
Furness, AJS;
Litchfield, K;
Joshi, K;
Rosenthal, R;
Ghorani, E;
Solomon, I;
... Quezada, SA; + view all
(2018)
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.
Cancer Cell
, 33
(4)
pp. 649-663.
10.1016/j.ccell.2018.02.010.
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Vargas, FA;
Furness, AJS;
Solomon, I;
Joshi, K;
Mekkaoui, L;
Lesko, MH;
Rota, EM;
... Quezada, SA; + view all
(2017)
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.
Immunity
, 46
(4)
pp. 577-586.
10.1016/j.immuni.2017.03.013.
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Walls, GM;
Oughton, JB;
Chalmers, AJ;
Brown, S;
Collinson, F;
Forster, MD;
Franks, KN;
... Greystoke, A; + view all
(2020)
CONCORDE: A phase I platform study of novel agents in combination with conventional radiotherapy in non-small-cell lung cancer.
Clinical and Translational Radiation Oncology
, 25
pp. 61-66.
10.1016/j.ctro.2020.09.006.
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Poster
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Rane, Jayant;
Harsanyi, Csilla;
Grimes, Helen;
Moinuddin, Syed;
Quingua, Kristina;
Petkar, Shabnam;
Dubash, Suraiya;
... Wilson, James; + view all
(2022)
Tumour location is important in selecting patients who may benefit from abdominal compression when receiving SABR for lung tumours.
Presented at: 20th Annual British Thoracic Oncology Group Conference 2022, Virtual conference.
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