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Number of items: 47.
Article
Alsulami, AF;
Torres, PHM;
Moghul, I;
Arif, SM;
Chaplin, AK;
Vedithi, SC;
Blundell, TL;
(2021)
COSMIC Cancer Gene Census 3D database: understanding the impacts of mutations on cancer targets.
Briefings in Bioinformatics
, 22
(6)
, Article bbab220. 10.1093/bib/bbab220.
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Alsulami, AF;
Thomas, SE;
Jamasb, AR;
Beaudoin, CA;
Moghul, I;
Bannerman, B;
Copoiu, L;
... Blundell, TL; + view all
(2021)
SARS-CoV-2 3D database: understanding the coronavirus proteome and evaluating possible drug targets.
Briefings in Bioinformatics
, 22
(2)
pp. 769-780.
10.1093/bib/bbaa404.
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Au, L;
Hatipoglu, E;
Robert de Massy, M;
Litchfield, K;
Beattie, G;
Rowan, A;
Schnidrig, D;
... TRACERx Renal Consortium; + view all
(2021)
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.
Cancer Cell
, 39
pp. 1497-1518.
10.1016/j.ccell.2021.10.001.
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Azzoni, E;
Frontera, V;
Anselmi, G;
Rode, C;
James, C;
Deltcheva, EM;
Demian, AS;
... de Bruijn, MFTR; + view all
(2021)
The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition.
Cell Reports
, 37
(11)
, Article 110103. 10.1016/j.celrep.2021.110103.
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Bentham, R;
Litchfield, K;
Watkins, TBK;
Lim, EL;
Rosenthal, R;
Martinez-Ruiz, C;
Hiley, CT;
... McGranahan, N; + view all
(2021)
Using DNA sequencing data to quantify T cell fraction and therapy response.
Nature
, 597
pp. 555-560.
10.1038/s41586-021-03894-5.
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Breeze, CE;
Batorsky, A;
Lee, MK;
Szeto, MD;
Xu, X;
McCartney, DL;
Jiang, R;
... Franceschini, N; + view all
(2021)
Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci.
Genome Medicine
, 13
(1)
, Article 74. 10.1186/s13073-021-00877-z.
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Brooks, LJ;
Clements, MP;
Burden, JJ;
Kocher, D;
Richards, L;
Devesa, SC;
Zakka, L;
... Parrinello, S; + view all
(2021)
The white matter is a pro-differentiative niche for glioblastoma.
Nature Communications
, 12
, Article 2184. 10.1038/s41467-021-22225-w.
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Childs, A;
Steele, CD;
Vesely, C;
Rizzo, FMM;
Ensell, L;
Lowe, H;
Dhami, P;
... Meyer, T; + view all
(2021)
Whole genome sequencing of single circulating tumor cells from neuroendocrine neoplasms.
Endocrine-Related Cancer
10.1530/ERC-21-0179.
(In press).
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Corpas, M;
Beck, S;
Glusman, G;
Shabani, M;
(2021)
Editorial: Personal Genomes: Accessing, Sharing, and Interpretation.
Frontiers in Genetics
, 12
, Article 687584. 10.3389/fgene.2021.687584.
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Dritsoula, A;
Kislikova, M;
Oomatia, A;
Webster, AP;
Beck, S;
Ponticos, M;
Lindsey, B;
... Caplin, B; + view all
(2021)
Epigenome-wide methylation profile of chronic kidney disease-derived arterial DNA uncovers novel pathways in disease-associated cardiovascular pathology.
Epigenetics
, 16
(7)
pp. 718-728.
10.1080/15592294.2020.1819666.
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Ellis, DA;
Reyes-Martín, F;
Rodríguez-López, M;
Cotobal, C;
Sun, X-M;
Saintain, Q;
Jeffares, DC;
... Bähler, J; + view all
(2021)
R-loops and regulatory changes in chronologically ageing fission yeast cells drive non-random patterns of genome rearrangements.
PLOS Genetics
, 17
(8)
, Article e1009784. 10.1371/journal.pgen.1009784.
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Fujimitsu, K;
Yamano, H;
(2021)
Dynamic regulation of mitotic ubiquitin ligase APC/C by coordinated Plx1 kinase and PP2A phosphatase action on a flexible Apc1 loop.
EMBO Journal
, Article ARTN e10. 10.15252/embj.2020107516.
(In press).
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Gangoso, E;
Southgate, B;
Bradley, L;
Rus, S;
Galvez-Cancino, F;
McGivern, N;
Güç, E;
... Pollard, SM; + view all
(2021)
Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.
Cell
10.1016/j.cell.2021.03.023.
(In press).
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Gerber, JP;
Russ, J;
Chandrasekar, V;
Offermann, N;
Lee, H-M;
Spear, S;
Guzzi, N;
... Salomoni, P; + view all
(2021)
Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation.
Nature Cell Biology
10.1038/s41556-021-00774-y.
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Goldberg, R;
Clough, JN;
Roberts, LB;
Sanchez, J;
Kordasti, S;
Petrov, N;
Hertweck, A;
... Lord, GM; + view all
(2021)
A Crohn’s Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling.
Journal of Crohn's and Colitis
, 15
(12)
pp. 2054-2065.
10.1093/ecco-jcc/jjab103.
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Hagan, AE;
Znati, SA;
Carter, R;
Westhorpe, A;
Macfarlane, WM;
Phillips, GJ;
Lloyd, AW;
... Lewis, AL; + view all
(2021)
Vandetanib-eluting radiopaque beads for chemoembolization: physicochemical evaluation and biological activity of vandetanib in hypoxia.
Anti-Cancer Drugs
10.1097/CAD.0000000000001082.
(In press).
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Henderson, S;
Pullabhatla, V;
Hertweck, A;
de Rinaldis, E;
Herrero, J;
Lord, GM;
Jenner, RG;
(2021)
The Th1 cell regulatory circuitry is largely conserved between human and mouse.
Life Science Alliance
, 4
(11)
, Article e202101075. 10.26508/lsa.202101075.
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Hertweck, A;
Jenner, RG;
(2021)
The Study of Protein–DNA Interactions in CD4+ T-Cells Using ChIPmentation.
Methods in Molecular Biology
, 2285
pp. 201-216.
10.1007/978-1-0716-1311-5_17.
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Jain, R;
Zhao, K;
Sheridan, JM;
Heinlein, M;
Kupresanin, F;
Abeysekera, W;
Hall, C;
... Gray, DHD; + view all
(2021)
Dual roles for LUBAC signaling in thymic epithelial cell development and survival.
Cell Death & Differentiation
, 28
(10)
pp. 2946-2956.
10.1038/s41418-021-00850-8.
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Kumari, R;
Hummerich, H;
Shen, X;
Fischer, M;
Litovchick, L;
Mittnacht, S;
DeCaprio, JA;
(2021)
Simultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence.
Scientific Reports
, 11
(1)
, Article 21506. 10.1038/s41598-021-01012-z.
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Lämmle, Bernhard;
(2021)
Endothelial Dysfunction, Atherosclerosis, and Increase of Von Willebrand Factor and Factor VIII: A Randomized Controlled Trial in Swine.
Thrombosis and Haemostasis
, 121
(05)
p. 552.
10.1055/a-1347-8761.
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Lee, L;
Alrasheed, N;
Khandelwal, G;
Fitzsimons, E;
Richards, H;
Wilson, W;
Chavda, SJ;
... Yong, K; + view all
(2021)
Increased Immune-Regulatory Receptor Expression on Effector T Cells as Early Indicators of Relapse Following Autologous Stem Cell Transplantation for Multiple Myeloma.
Frontiers Immunology
, 12
, Article 618610. 10.3389/fimmu.2021.618610.
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Litchfield, K;
Reading, JL;
Puttick, C;
Thakkar, K;
Abbosh, C;
Bentham, R;
Watkins, TBK;
... Swanton, C; + view all
(2021)
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.
Cell
, 184
(3)
596-614.e14.
10.1016/j.cell.2021.01.002.
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Lyskjaer, I;
De Noon, S;
Tirabosco, R;
Rocha, AM;
Lindsay, D;
Amary, F;
Ye, H;
... Flanagan, AM; + view all
(2021)
DNA methylation-based profiling of bone and soft tissue tumours: a validation study of the 'DKFZ Sarcoma Classifier'.
The Journal of Pathology: Clinical Research
10.1002/cjp2.215.
(In press).
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Maile, H;
Li, J-PO;
Gore, D;
Leucci, M;
Mulholland, P;
Hau, S;
Szabo, A;
... Pontikos, N; + view all
(2021)
Machine Learning Algorithms to Detect Subclinical Keratoconus: Systematic Review.
JMIR Medical Informatics
, 9
(12)
, Article e27363. 10.2196/27363.
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Marqués-Torrejón, MÁ;
Williams, CAC;
Southgate, B;
Alfazema, N;
Clements, MP;
Garcia-Diaz, C;
Blin, C;
... Pollard, SM; + view all
(2021)
LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells.
Nature Communications
, 12
(1)
, Article 2594. 10.1038/s41467-021-22813-w.
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Martinez-Miguel, VE;
Lujan, C;
Espie-Caullet, T;
Martinez-Martinez, D;
Moore, S;
Backes, C;
Gonzalez, S;
... Bjedov, I; + view all
(2021)
Increased fidelity of protein synthesis extends lifespan.
Cell Metabolism
10.1016/j.cmet.2021.08.017.
(In press).
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McErlean, P;
Bell, CG;
Hewitt, RJ;
Busharat, Z;
Ogger, PP;
Ghai, P;
Albers, GJ;
... Byrne, AJ; + view all
(2021)
DNA Methylome Alterations are Associated with Airway Macrophage Differentiation and Phenotype During Lung Fibrosis.
American Journal of Respiratory and Critical Care Medicine
, 204
(8)
pp. 954-966.
10.1164/rccm.202101-0004OC.
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Montinaro, A;
Areso Zubiaur, I;
Saggau, J;
Kretz, A-L;
Ferreira, RMM;
Hassan, O;
Kitzig, E;
... Walczak, H; + view all
(2021)
Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers.
Cell Death & Differentiation
10.1038/s41418-021-00869-x.
(In press).
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Moore, A;
Machiela, MJ;
Machado, M;
Wang, SS;
Kane, E;
Slager, SL;
Zhou, W;
... Berndt, SI; + view all
(2021)
Genome-wide homozygosity and risk of four non-Hodgkin lymphoma subtypes.
Journal of Translational Genetics and Genomics
, 5
pp. 200-217.
10.20517/jtgg.2021.08.
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Pollara, G;
Turner, CT;
Rosenheim, J;
Chandran, A;
Bell, LCK;
Khan, A;
Patel, A;
... Noursadeghi, M; + view all
(2021)
Exaggerated IL-17A activity in human in vivo recall responses discriminates active tuberculosis from latent infection and cured disease.
Science Translational Medicine
, 13
(592)
, Article eabg7673. 10.1126/scitranslmed.abg7673.
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Richardson, SE;
Ghazanfari, R;
Chhetri, J;
Enver, T;
Böiers, C;
(2021)
In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture.
STAR Protocols
, 2
(2)
, Article 100420. 10.1016/j.xpro.2021.100420.
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Roberts, Luke B;
Jowett, Geraldine M;
Read, Emily;
Zabinski, Tomas;
Berkachy, Rita;
Selkirk, Murray E;
Jackson, Ian;
... Lord, Graham M; + view all
(2021)
MicroRNA-142 Critically Regulates Group 2 Innate Lymphoid Cell Homeostasis and Function.
The Journal of Immunology
, 206
(11)
pp. 2725-2739.
10.4049/jimmunol.2000647.
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Rodríguez-Hernández, Guillermo;
Casado-García, Ana;
Isidro-Hernández, Marta;
Picard, Daniel;
Raboso-Gallego, Javier;
Alemán-Arteaga, Silvia;
Orfao, Alberto;
... Vicente-Dueñas, Carolina; + view all
(2021)
The Second Oncogenic Hit Determines the Cell Fate of ETV6-RUNX1 Positive Leukemia.
Frontiers in Cell and Developmental Biology
, 9
, Article 704591. 10.3389/fcell.2021.704591.
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Roehrig, AE;
Klupsch, K;
Oses-Prieto, JA;
Chaib, S;
Henderson, S;
Emmett, W;
Young, LC;
... Rodriguez-Viciana, P; + view all
(2021)
Cell-cell adhesion regulates Merlin/NF2 interaction with the PAF complex.
PLoS One
, 16
(8)
, Article e0254697. 10.1371/journal.pone.0254697.
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Silvestre Patallo, I;
Carter, R;
Maughan, D;
Nisbet, A;
Schettino, G;
Subiel, A;
(2021)
Evaluation of a micro ionization chamber for dosimetric measurements in image-guided preclinical irradiation platforms.
Physics in Medicine and Biology
10.1088/1361-6560/ac3b35.
(In press).
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Skalska, L;
Begley, V;
Beltran, M;
Lukauskas, S;
Khandelwal, G;
Faull, P;
Bhamra, A;
... Jenner, RG; + view all
(2021)
Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin.
Molecular Cell
, 81
(14)
2944-2959.e10.
10.1016/j.molcel.2021.05.026.
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Smeeth, Demelza;
Beck, Stephan;
Karam, Elie G;
Pluess, Michael;
(2021)
The role of epigenetics in psychological resilience.
The Lancet Psychiatry
, 8
(7)
pp. 620-629.
10.1016/S2215-0366(20)30515-0.
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Turati, VA;
Guerra-Assunção, JA;
Potter, NE;
Gupta, R;
Ecker, S;
Daneviciute, A;
Tarabichi, M;
... Enver, T; + view all
(2021)
Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia.
Nature Cancer
, 2
pp. 835-852.
10.1038/s43018-021-00219-3.
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Vohringer, Harald S;
Sanderson, Theo;
Sinnott, Matthew;
De Maio, Nicola;
Thuy, Nguyen;
Goater, Richard;
Schwach, Frank;
... Gerstung, Moritz; + view all
(2021)
Genomic reconstruction of the SARS-CoV-2 epidemic in England.
Nature
, 600
(7889)
pp. 506-511.
10.1038/s41586-021-04069-y.
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Watt, S;
Vasquez, L;
Walter, K;
Mann, AL;
Kundu, K;
Chen, L;
Sims, Y;
... Soranzo, N; + view all
(2021)
Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease.
Nature Communications
, 12
, Article 2298. 10.1038/s41467-021-22548-8.
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Willms, A;
Schupp, H;
Poelker, M;
Adawy, A;
Debus, JF;
Hartwig, T;
Krichel, T;
... Trauzold, A; + view all
(2021)
TRAIL-receptor 2-a novel negative regulator of p53.
Cell Death & Disease
, 12
(8)
, Article 757. 10.1038/s41419-021-04048-1.
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Wong, DCS;
Olivera, M;
Yu, J;
Szabo, A;
Moghul, I;
Balaskas, KS;
Luben, R;
... Keane, PA; + view all
(2021)
Cloud-based genomics pipelines for ophthalmology: Reviewed from research to clinical practice.
Journal for Modeling in Ophthalmology
, 3
(1)
pp. 101-140.
10.35119/maio.v3i1.115.
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Zoumpoulidou, G;
Alvarez-Mendoza, C;
Mancusi, C;
Ahmed, R-M;
Denman, M;
Steele, CD;
Tarabichi, M;
... Mittnacht, S; + view all
(2021)
Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma.
Nature Communications
, 12
(1)
, Article 7064. 10.1038/s41467-021-27291-8.
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Working / discussion paper
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Garcia-Diaz, Claudia;
Mereu, Elisabetta;
Clements, Melanie;
Pöysti, Anni;
Galvez-Cancino, Felipe;
Castillo, Simon;
Courtot, Lilas;
... Parrinello, Simona; + view all
(2021)
Glioblastoma cell fate is differentially regulated by the microenvironments of the tumour bulk and infiltrative margin.
bioRxiv: Cold Spring Harbor, NY, USA.
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Thesis
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Moghul, Muhammad Ismail;
(2021)
Imputation Aided Methylation Analysis.
Doctoral thesis (Ph.D), UCL (University College London).
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Vila De Mucha, Maria Antonieta;
(2021)
Transcriptional regulation of tumour infiltrating cytotoxic CD4+ T cell differentiation.
Doctoral thesis (Ph.D), UCL (University College London).
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