UCL Discovery

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Acevedo-Arozena, A and Kalmar, B and Essa, S and Ricketts, T and Joyce, P and Kent, R and Rowe, C and Parker, A and Gray, A and Hafezparast, M and Thorpe, JR and Greensmith, L and Fisher, EMC (2011) A comprehensive assessment of the SOD1(G93A) low-copy transgenic mouse, which models human amyotrophic lateral sclerosis. DIS MODEL MECH , 4 (5) 686 - 700. 10.1242/dmm.007237. An open access publication

Achilli, F and Boyle, S and Kieran, D and Chia, R and Hafezparast, M and Martin, JE and Schiavo, G and Greensmith, L and Bickmore, W and Fisher, EMC (2005) The SOD1 transgene in the G93A mouse model of amyotrophic lateral sclerosis lies on distal mouse chromosome 12. AMYOTROPH LATERAL SC , 6 (2) 111 - 114. 10.1080/14660820510035351.

Achilli, F and Bros-Facer, V and Williams, HP and Banks, GT and AlQatari, M and Chia, R and Tucci, V and Groves, M and Nickols, CD and Seburn, KL and Kendall, R and Cader, MZ and Talbot, K and van Minnen, J and Burgess, RW and Brandner, S and Martin, JE and Koltzenburg, M and Greensmith, L and Nolan, PM and Fisher, EMC (2009) An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. DIS MODEL MECH , 2 (7-8) 359 - 373. 10.1242/dmm.002527. An open access publication

Ahmad-Annuar, A and Shah, P and Hafezparast, M and Hummerich, H and Witherden, AS and Morrison, KE and Shaw, PJ and Kirby, J and Warner, TT and Crosby, A and Proukakis, C and Wilkinson, P and Orrell, RW and Bradley, L and Martin, JE and Fisher, EMC (2003) No association with common Caucasian genotypes in exons 8, 13 and 14 of the human cytoplasmic dynein heavy chain gene (DNCHC1) and familial motor neuron disorders. AMYOTROPH LATERAL SC , 4 (3) 150 - 157.

Ahmad-Annuar, A and Tabrizi, SJ and Fisher, EMC (2003) Mouse models as a tool for understanding neurodegenerative diseases. CURR OPIN NEUROL , 16 (4) 451 - 458. 10.1097/01.wco.0000084221.82329.29.

Ahmed, and Dhanasekaran, and Tong, and Wiseman, F and Fisher, EMC and Tybulewicz, V and Gardiner, (2013) Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain. Molecular Genetics and Genomics: an international journal

Alford, KA and Slender, A and Vanes, L and Li, Z and Fisher, EMC and Nizetic, D and Orkin, SH and Roberts, I and Tybulewicz, VLJ (2010) Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome. BLOOD , 115 (14) 2928 - 2937. 10.1182/blood-2009-06-227629.

Ashworth, A and Lloyd, S and Brown, J and Gydesen, S and Sorensen, SA and Brun, A and Englund, E and Humphreys, C and Housman, D and Badura, M and Stanton, V and Taylor, K and Cameron, J and Munroe, D and Johansson, J and Rossor, M and Fisher, EMC and Collinge, J (1999) Molecular genetic characterisation of frontotemporal dementia on chromosome 3. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS , 10 93 - 101.

Ateh, DD and Hussain, IK and Mustafa, AH and Price, KM and Gulati, R and Nickols, CD and Bird, MM and Greensmith, L and Hafezparast, M and Fisher, EMC and Baker, CS and Martin, JE (2008) Dynein-dynactin complex subunits are differentially localized in brain and spinal cord, with selective involvement in pathological features of neurodegenerative disease. NEUROPATH APPL NEURO , 34 (1) 88 - 94. 10.1111/j.1365-2990.2007.00924.x.

Banks, G.T. and Bros-Facer, V. and Williams, H.P. and Chia, R. and Achilli, F. and Bryson, J.B. and Greensmith, L. and Fisher, E.M.C. (2009) Mutant glycyl-tRNA synthetase (Gars) ameliorates SOD1G93A motor neuron degeneration phenotype but has little affect on Loa dynein heavy chain mutant mice. PLoS ONE , 4 (7) , Article e6218. 10.1371/journal.pone.0006218. An open access publication. A version is also available from UCL Discovery.

Banks, GT and Bros-Facer, V and Williams, HP and Chia, R and Achilli, F and Bryson, JB and Greensmith, L and Fisher, EMC (2009) Mutant Glycyl-tRNA Synthetase (Gars) Ameliorates SOD1(G93A) Motor Neuron Degeneration Phenotype but Has Little Affect on Loa Dynein Heavy Chain Mutant Mice. PLOS ONE , 4 (7) , Article e6218. 10.1371/journal.pone.0006218. An open access publication. A version is also available from UCL Discovery.

Banks, GT and Fisher, EMC (2008) Cytoplasmic dynein could be key to understanding neurodegeneration. GENOME BIOL , 9 (3) , Article 214. 10.1186/gb-2008-9-3-214. An open access publication

Banks, GT and Haas, MA and Line, S and Shepherd, HL and AlQatari, M and Stewart, S and Rishal, I and Philpott, A and Kalmar, B and Kuta, A and Groves, M and Parkinson, N and Acevedo-Arozena, A and Brandner, S and Bannerman, D and Greensmith, L and Hafezparast, M and Koltzenburg, M and Deacon, R and Fainzilber, M and Fisher, EMC (2011) Behavioral and Other Phenotypes in a Cytoplasmic Dynein Light Intermediate Chain 1 Mutant Mouse. J NEUROSCI , 31 (14) 5483 - 5494. 10.1523/JNEUROSCI.5244-10.2011. An open access publication

Banks, GT and Kuta, A and Isaacs, AM and Fisher, EMC (2008) TDP-43 is a culprit in human neurodegeneration, and not just an innocent bystander. MAMM GENOME , 19 (5) 299 - 305. 10.1007/s00335-008-9117-x. An open access publication

Beck, JA and Lloyd, S and Hafezparast, M and Lennon-Pierce, M and Eppig, JT and Festing, MFW and Fisher, EMC (2000) Genealogies of mouse inbred strains. NAT GENET , 24 (1) 23 - +.

Becker, EBE and Olivera, PL and Glitsch, MD and Banks, GT and Achilli, F and Hardy, A and Nolan, PM and Fisher, EMC and Davies, KE (2009) A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice. P NATL ACAD SCI USA , 106 (16) 6706 - 6711. 10.1073/pnas.0810599106.

Bermingham, N and Gilmour, F and Martin, JE and Fisher, EMC (1995) Human glial cell line-derived neurotrophic factor (GDNF) maps to chromosome 5. Hum Genet , 96 671 - 673.

Bermingham, N and Hernandez, D and Balfour, A and Gilmour, F and Martin, JE and Fisher, EMC (1995) Mapping TNNC1, the gene which encodes cardiac troponin I in the human and the mouse. Genomics , 30 620 - 622.

Bermingham, N and Martin, JE and Fisher, EMC (1996) The mouse lysosomal membrane protein 1 gene as a candidate for the motorneuron degeneration (mnd) locus. Genomics , 32 266 - 271.

Bermingham, N and McKay, T and Hoyle, J and Hernandez, D and Martin, JE and Fisher, EMC (1996) The gene encoding tripeptidyl peptidase II maps to chromosome 1 in the mouse. Mamm Genome , 7 390 - ?.

Bermingham, NA and Rauf, S and Katsanis, N and Martin, JE and Hunter, AJ and Fisher, EMC (1998) The immunophilin FKBP4 (FKBP52/FKBP59) maps to the distal short arm of human chromosome 12. Mamm Genome , 9 268 - ?.

Bowen, S and Ateh, DD and Deinhardt, K and Bird, MM and Price, KM and Baker, CS and Robson, JC and Swash, M and Shamsuddin, W and Kawar, S and El-Tawil, T and Roos, J and Hoyle, A and Nickols, CD and Knowles, CH and Pullen, AH and Luthert, PJ and Weller, RO and Hafezparast, M and Franklin, RJM and Revesz, T and King, RHM and Berninghausen, O and Fisher, EMC and Schiavo, G and Martin, JE (2007) The phagocytic capacity of neurones. EUR J NEUROSCI , 25 (10) 2947 - 2955. 10.1111/j.1460-9568.2007.05554.x.

Brockdorff, N and Cross, GS and Cavanna, JS and Fisher, EMC and Lyon, MF and Davies, KE and Brown, SDM (1987) The mapping of a cDNA from the human X linked Duchenne muscular dystrophy gene to the mouse X chromosome. Nature , 328 166 - 168.

BROCKDORFF, N and FISHER, EMC and CAVANNA, J and LYON, MF and BROWN, SDM (1987) THE MOLECULAR MAPPING OF THE MOUSE X-CHROMOSOME. GENET RES , 49 (3) 258 - 258.

BROCKDORFF, N and FISHER, EMC and CAVANNA, JS and LYON, MF and BROWN, SDM (1987) CONSTRUCTION OF A DETAILED MOLECULAR MAP OF THE MOUSE X-CHROMOSOME BY MICROCLONING AND INTERSPECIFIC CROSSES. EMBO J , 6 (11) 3291 - 3297.

BROCKDORFF, N and FISHER, EMC and ORKIN, SH and LYON, MF and BROWN, SDM (1988) LOCALIZATION OF THE HUMAN X-LINKED GENE FOR CHRONIC GRANULOMATOUS-DISEASE TO THE MOUSE X-CHROMOSOME - IMPLICATIONS FOR X-CHROMOSOME EVOLUTION. CYTOGENET CELL GENET , 48 (2) 124 - 125.

Brown, J and Gydesen, S and Johannsen, P and Gade, A and Skibinski, G and Chakrabarti, L and Brun, A and Spillantini, M and Yancopoulou, D and Thusgaard, T and Sorensen, A and Fisher, E and Collinge, J and FreJA, (2004) Frontotemporal dementia linked to chromosome 3. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS , 17 (4) 274 - 276. 10.1159/000077153.

BROWN, SDM and BROCKDORFF, N and CAVANNA, JS and FISHER, EMC and GREENFIELD, AJ and LYON, MF and NASIR, J (1988) THE LONG-RANGE MAPPING OF MAMMALIAN CHROMOSOMES. CURR TOP MICROBIOL , 137 3 - 12.

Canzonetta, C and Mulligan, C and Deutsch, S and Ruf, S and O'Doherty, A and Lyle, R and Borel, C and Lin-Marq, N and Delom, F and Groet, J and Schnappauf, F and De Vita, S and Averill, S and Priestley, JV and Martin, JE and Shipley, J and Denyer, G and Epstein, CJ and Fillat, C and Estivill, X and Tybulewicz, VLJ and Fisher, EMC and Antonarakis, SE and Nizetic, D (2008) DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome. AM J HUM GENET , 83 (3) 388 - 400. 10.1016/j.ajhg.2008.08.012.

Chakrabarti, L and FReJA, (2001) Clinical and molecular characterisation of frontotemporal dementia linked to human chromosome 3. AMERICAN JOURNAL OF HUMAN GENETICS , 69 (4) 278 - 278.

Chia, R and Achilli, F and Festing, MFW and Fisher, EMC (2005) The origins and uses of mouse outbred stocks. NAT GENET , 37 (11) 1181 - 1186. 10.1038/ng1665.

Chia, R and Tattum, MH and Jones, S and Collinge, J and Fisher, EMC and Jackson, GS (2010) Superoxide Dismutase 1 and tgSOD1(G93A) Mouse Spinal Cord Seed Fibrils, Suggesting a Propagative Cell Death Mechanism in Amyotrophic Lateral Sclerosis. PLOS ONE , 5 (5) , Article e10627. 10.1371/journal.pone.0010627. An open access publication. A version is also available from UCL Discovery.

Chio, A and Schymick, JC and Restagno, G and Scholz, SW and Lombardo, F and Lai, SL and Mora, G and Fung, HC and Britton, A and Arepalli, S and Gibbs, JR and Nalls, M and Berger, S and Kwee, LC and Oddone, EZ and Ding, JH and Crews, C and Rafferty, I and Washecka, N and Hernandez, D and Ferrucci, L and Bandinelli, S and Guralnik, J and Macciardi, F and Torri, F and Lupoli, S and Chanock, SJ and Thomas, G and Hunter, DJ and Gieger, C and Wichmann, HE and Calvo, A and Mutani, R and Battistini, S and Giannini, F and Caponnetto, C and Mancardi, GL and La Bella, V and Valentino, F and Monsurro, MR and Tedeschi, G and Marinou, K and Sabatelli, M and Conte, A and Mandrioli, J and Sola, P and Salvi, F and Bartolomei, I and Siciliano, G and Carlesi, C and Orrell, RW and Talbot, K and Simmons, Z and Connor, J and Pioro, EP and Dunkley, T and Stephan, DA and Kasperaviciute, D and Fisher, EM and Jabonka, S and Sendtner, M and Beck, M and Bruijn, L and Rothstein, J and Schmidt, S and Singleton, A and Hardy, J and Traynor, BJ (2009) A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. HUM MOL GENET , 18 (8) 1524 - 1532. 10.1093/hmg/ddp059.

Cleary, JO and Wiseman, FK and Norris, FC and Price, AN and Choy, M and Tybulewicz, VLJ and Ordidge, RJ and Brandner, S and Fisher, EMC and Lythgoe, MF (2011) Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain. NEUROIMAGE , 56 (3) 974 - 983. 10.1016/j.neuroimage.2011.01.082.

Cole, SE and Wiltshire, T and Rue, EE and Morrow, D and Hieter, P and Brahe, C and Fisher, EMC and Katsanis, N and Reeves, RH (1999) High-resolution comparative physical mapping of mouse Chromosome 10 in the region of homology with human Chromosome 21. Mammalian Genome , 10 (3) 229 - 234.

Curtin, JA and Quint, E and Tsipouri, V and Arkell, RM and Cattanach, B and Copp, AJ and Henderson, DJ and Spurr, N and Stanier, P and Fisher, EM and Nolan, PM and Steel, KP and Brown, SDM and Gray, IC and Murdoch, JN (2003) Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. CURR BIOL , 12 (13) 1129 - 1133. 10.1016/S0960-9822(03)00374-9.

De Vita, S and Canzonetta, C and Mulligan, C and Delom, F and Groet, J and Baldo, C and Vanes, L and Dagna-Bricarelli, F and Hoischen, A and Veltman, J and Fisher, EMC and Tybulewicz, VLJ and Nizetic, D (2010) Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome. ONCOGENE , 29 (46) 6102 - 6114. 10.1038/onc.2010.351.

Deng, W and Garrett, C and Dombert, B and Soura, V and Banks, G and Fisher, EMC and van der Brug, MP and Hafezparast, M (2011) Neurodegenerative mutation in cytoplasmic dynein alters its organization and dynein-dynactin and dynein-kinesin interactions. J Biol Chem , 285 (51) 39922 - 39932.

Devoy, A and Bunton-Stasyshyn, RK and Tybulewicz, VL and Smith, AJ and Fisher, EM (2012) Genomically humanized mice: technologies and promises. Nat Rev Genet , 13 (1) 14 - 20. 10.1038/nrg3116.

Doherty, AMO and Fisher, EMC (2003) Microcell-mediated chromosome transfer (MMCT): small cells with huge potential. MAMM GENOME , 14 (9) 583 - 592. 10.1007/s00335-003-4002-0.

Duchon, A and Pothion, S and Brault, V and Sharp, AJ and Tybulewicz, VLJ and Fisher, EMC and Herault, Y (2011) The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome. BEHAV BRAIN RES , 217 (2) 271 - 281. 10.1016/j.bbr.2010.10.023.

Dunlevy, L and Bennett, M and Slender, A and Lana-Elola, E and Tybulewicz, VL and Fisher, EMC and Mohun, T (2010) Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse. CARDIOVASC RES , 88 (2) 287 - 295. 10.1093/cvr/cvq193.

El-Kadi, AM and Bros-Facer, V and Deng, WH and Philpott, A and Stoddart, E and Banks, G and Jackson, GS and Fisher, EMC and Duchen, MR and Greensmith, L and Moore, AL and Hafezparast, M (2010) The Legs at odd angles (Loa) Mutation in Cytoplasmic Dynein Ameliorates Mitochondrial Function in SOD1(G93A) Mouse Model for Motor Neuron Disease. J BIOL CHEM , 285 (24) 18627 - 18639. 10.1074/jbc.M110.129320. An open access publication

Festing, MFW and Fisher, EMC (2000) Mighty mice - Clarence Little's brainwave gave biomedical researchers their best friend. NATURE , 404 (6780) 815 - 815.

Filimonenko, M and Stuffers, S and Raiborg, C and Yamamoto, A and Malerod, L and Fisher, EMC and Isaacs, A and Brech, A and Stenmark, H and Simonsen, A (2007) Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. J CELL BIOL , 179 (3) 485 - 500.

Fisher, EMC (2003) The mouse: genetics and genome. Genetics Society Newsletter , 50 7 - 9.

Fisher, EMC (1998) Modelling motor neuron degenerative disease. Neuropathol. Appl. Neurobiol. , 24 90 - ?.

Fisher, EMC (1997) The contribution of the mouse to advances in human genetics. Advances in Genetics , 35 155 - 205. 10.1016/S0065-2660(08)60450-2.

Fisher, EMC (1995) Why aren't we all bacteria. Immunology News , 2 100 - 103.

Fisher, EMC (1993) Much ado about cloning. BMJ , 307 (6911) 1074 - 1075.

Fisher, EMC (1993) Working with the media. Physiological Society Magazine , 8 25 - 25.

Fisher, EMC (1991) On air. Science and Public Affairs , 1 5 - 6.

Fisher, EMC and Alitalo, T and Luoh, SW and de-la-Chapelle, A and Page, DC (1990) Human sex-chromosome-specific repeats within a region of pseudoautosomal/Yq homology. Genomics , 7 625 - 628.

Fisher, EMC and Beer-Romero, P and Brown, LG and Ridley, A and McNeil, JA and Bentley-Lawrence, J and Willard, HF and Bieber, F and Page, DC (1990) Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome. Cell , 63 1205 - 1218.

FISHER, EMC and CAVANNA, JS and BROCKDORFF, N and LYON, MF and BROWN, SDM (1986) THE MOLECULAR MAPPING OF THE MOUSE X-CHROMOSOME. HEREDITY , 57 286 - 286.

Fisher, EMC and Cavanna, JS and Brown, SDM (1985) Microdissection and microcloning of the mouse X chromosome. Proc. Natl. Acad. Sci. , 82 5846 - 5849.

Fisher, EMC and Lana-Elola, E and Watson, SD and Vassiliou, G and Tybulewicz, VLJ (2009) New approaches for modelling sporadic genetic disease in the mouse. DIS MODEL MECH , 2 (9-10) 446 - 453. 10.1242/dmm.001644. An open access publication

Fisher, EMC and Scambler, PJ (1994) Human haploinsufficiency - one for sorrow, two for joy. Nature Genetics , 7 5 - 7.

Fisher, EMC and Telling, G and Collinge, J (1998) Prions and the prion disorders. Mamm Genome , 9 (7) 497 - 502.

Fisher, EMC and Tybulewicz, VLJ (2006) Understanding Down Syndrome. Science and Public Affairs , 9

Fratta, P and Malik, B and Gray, A and La Spada, A and Hanna, M and Fisher, EMC and Greensmith, L (2013) FUS is not dysregulated by the spinal bulbar muscular atrophy androgen receptor polyglutamine repeat expansion. Neurobiology of Aging

Fratta, P and Malik, B and Gray, A and La Spada, AR and Hanna, MG and Fisher, EM and Greensmith, L (2013) FUS is not dysregulated by the spinal bulbar muscular atrophy androgen receptor polyglutamine repeat expansion. Neurobiol Aging , 34 (5) 1516.e17 - 1516.e19. 10.1016/j.neurobiolaging.2012.09.008.

Fratta, P and Mizielinska, S and Nicoll, AJ and Zloh, M and Fisher, EM and Parkinson, G and Isaacs, AM (2012) C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes. Sci Rep , 2 1016 - ?. 10.1038/srep01016.

Galante, M and Jani, H and Vanes, L and Daniel, H and Fisher, EMC and Tybulewicz, VLJ and Bliss, TVP and Morice, E (2009) Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome. HUM MOL GENET , 18 (8) 1449 - 1463. 10.1093/hmg/ddp055.

Galante, M. and Jani, H. and Vanes, L. and Daniel, H. and Fisher, E.M.C. and Tybulewicz, V.L.J. and Bliss, T.V.P. and Morice, E. (2009) Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome. Human Molecular Genetics , 18 (8) pp. 1449-1463. 10.1093/hmg/ddp055. An open access version is available from UCL Discovery

Ghazi-Noori, S and Froud, KE and Mizielinska, S and Powell, C and Smidak, M and Fernandez de Marco, M and O'Malley, C and Farmer, M and Parkinson, N and Fisher, EM and Asante, EA and Brandner, S and Collinge, J and Isaacs, AM (2012) Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice. Brain , 135 (Pt 3) 819 - 832. 10.1093/brain/aws006.

Gribble, SM and Wiseman, FK and Clayton, S and Prigmore, E and Langley, E and Yang, F and Maguire, S and Fu, B and Rajan, D and Sheppard, O and Scott, C and Hauser, H and Stephens, PJ and Stebbings, LA and Ng, BL and Fitzgerald, T and Quail, MA and Banerjee, R and Rothkamm, K and Tybulewicz, VLJ and Fisher, EMC and Carter, NP (2013) Massively Parallel Sequencing Reveals the Complex Structure of an Irradiated Human Chromosome on a Mouse Background in the Tc1 Model of Down Syndrome. PLOS ONE , 8 (4) , Article ARTN e60482. 10.1371/journal.pone.0060482. An open access publication

Grizenkova, J and Akhtar, S and Hummerich, H and Tomlinson, A and Asante, EA and Wenborn, A and Fizet, J and Poulter, M and Wiseman, FK and Fisher, EM and Tybulewicz, VL and Brandner, S and Collinge, J and Lloyd, SE (2012) Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice. Proc Natl Acad Sci U S A , 109 (34) 13722 - 13727. 10.1073/pnas.1208917109.

Gydesen, S and Brown, JM and Brun, A and Chakrabarti, L and Gade, A and Johannsen, P and Rossor, M and Thusgaard, T and Grove, A and Fisher, EMC and Collinge, J and Sorensen, SA (2004) Chromosome 3 linked frontotemporal dementia (FTD-3). Dementia Review (1/2004)

Gydesen, S and Brown, JM and Brun, A and Chakrabarti, L and Gade, A and Johannsen, P and Rossor, M and Thusgaard, T and Grove, A and Yancopoulou, D and Spillantini, MG and Fisher, EMC and Collinge, J and Sorensen, SA (2002) Chromosome 3 linked frontotemporal dementia (FTD-3). NEUROLOGY , 59 (10) 1585 - 1594.

Hafezparast, M and Ahmad-Annuar, A and Hummerich, H and Shah, P and Ford, M and Baker, C and Bowen, S and Martin, JE and Fisher, EMC (2003) Paradigms for the identification of new genes in motor neuron degeneration. AMYOTROPH LATERAL SC , 4 (4) 249 - 257. 10.1080/14660820310016084.

Hafezparast, M and Ahmad-Annuar, A and Wood, NW and Tabrizi, SJ and Fisher, EMC (2003) Mouse models for neurological disease. Adv Clin Neurosci , 13 305 - ?.

Hafezparast, M and Ahmad-Annuar, A and Wood, NW and Tabrizi, SJ and Fisher, EMC (2002) Mouse models for neurological disease. LANCET NEUROL , 1 (4) 215 - 224.

Hafezparast, M and Ball, S and Nicholson, SJ and Witherden, A and Arac, D and Broadway, N and Saggerson, D and Cooper, E and Naase, M and Gokhale, S and Quant, P and Lascelles, C and Nickols, C and Baker, CS and Peters, J and Martin, JE and Fisher, EMC (2002) A new mouse mutant, skijumper. MAMM GENOME , 13 (7) 359 - 364. 10.1007/s003350030008.

Hafezparast, M and Brandner, S and Linehan, J and Martin, JE and Collinge, J and Fisher, EMC (2005) Prion disease incubation time is not affected in mice heterozygous for a dynein mutation. BIOCHEM BIOPH RES CO , 326 (1) 18 - 22. 10.1016/j.bbrc.2004.10.206.

Hafezparast, M and Fisher, EMC (1999) Polyglutamine diseases. Trend Genet , 15 222 - ?.

Hafezparast, M and Fisher, EMC (1998) Wasted by an elongation factor. Trends Genet , 14 215 - 217.

Hafezparast, M and Klocke, R and Ruhrberg, C and Marquardt, A and Ahmad-Annuar, A and Bowen, S and Lalli, G and Witherden, AS and Hummerich, H and Nicholson, S and Morgan, PJ and Oozageer, R and Priestley, JV and Averill, S and King, VR and Ball, S and Peters, J and Toda, T and Yamamoto, A and Hiraoka, Y and Augustin, M and Korthaus, D and Wattler, S and Wabnitz, P and Dickneite, C and Lampel, S and Boehme, F and Peraus, G and Popp, A and Rudelius, M and Schlegel, J and Fuchs, H and de Angelis, MH and Schiavo, G and Shima, DT and Russ, AP and Stumm, G and Martin, JE and Fisher, EMC (2003) Mutations in dynein link motor neuron degeneration to defects in retrograde transport. SCIENCE , 300 (5620) 808 - 812.

Hafezparast, M and Witherden, A and Nicholson, S and Bermingham, N and Mackin, J and ten Asbroek, A and Ball, S and Peters, J and Baas, F and Martin, JE and Fisher, EMC (1999) The kinesin light chain gene: its mapping and exclusion in mouse and human forms of inherited motor neuron degeneration. NEUROSCI LETT , 273 (1) 49 - 52.

Hafezparast, M. and Klocke, R. and Ruhrberg, C. and Marquardt, A. and Ahmad-Annuar, A. and Bowen, S. and Lalli, G. and Witherden, A.S. and Hummerich, H. and Nicholson, S. and Morgan, P.J. and Oozageer, R. and Priestley, J.V. and Averill, S. and King, V.R. and Ball, S. and Peters, J. and Toda, T. and Yamamoto, A. and Hiraoka, Y. and Augustin, M. and Korthaus, D. and Wattler, S. and Wabnitz, P. and Dickneite, C. and Lampel, S. and Boehme, F. and Peraus, G. and Popp, A. and Rudelius, M. and Schlegel, J. and Fuchs, H. and de Angelis, M.H. and Schiavo, G. and Shima, D.T. and Russ, A.P. and Stumm, G. and Martin, J.E. and Fisher, E.M.C. (2003) Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science , 300 (5620) pp. 808-812. 10.1126/science.1083129.

Hamvas, RMJ and Zinn, A and Keer, JT and Fisher, EMC and Beer-Romero, P and Brown, SDM and Page, D (1992) Rps4 maps near the inactivation center on the mouse X chromosome. Genomics , 12 363 - 367.

Hernandez, D and Fisher, EMC (1999) Mouse autosomal trisomy - two’s company, three’s a crowd. Trends in Genetics , 15 241 - 247.

Hernandez, D and Fisher, EMC (1996) Down syndrome genetics: unravelling a multifactorial disorder. Hum Mol Genet , 5 1411 - 1416.

Hernandez, D and Mee, PJ and Martin, JE and Tybulewicz, VLJ and Fisher, EMC (1999) Transchromosomal mouse embryonic stem cell lines that contain a freely segregating whole or partial human chromosome 21. Human Molecular Genetics , 8 (5) 923 - 933.

Hernandez, D and Pannett, A and Tybulewicz, V and Fisher, EMC (1995) Highly polymorphic sequence at D21S1448 mapping close to D21S55. Hum Genet , 95 721 - 722.

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Pfister, KK and Shah, PR and Hummerich, H and Russ, A and Cotton, J and Annuar, AA and King, SM and Fisher, EMC (2006) Genetic analysis of the cytoplasmic dynein subunit families. PLOS GENET , 2 (1) , Article E1. 10.1371/journal.pgen.0020001. An open access publication

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Ramos, VC and Vidal-Taboada, J and Bergonon, S and Egeo, A and Fisher, EMC and Scartezzini, P and Oliva, R (2002) Characterisation and expression analysis of the WDR9 gene, located in the Down critical region-2 of the human chromosome 21. Biochim Biophys Acta , 1577 (3) 377 - 383.

Ramos, VC and Vidal-Taboada, JM and Bergonon, S and Egeo, A and Fisher, EMC and Scartezzini, P and Oliva, R (2002) Characterisation and expression analysis of the WDR9 gene, located in the Down critical region-2 of the human chromosome 21. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression , 1577 (3) 377 - 383.

Rastan, S and Hough, T and Kierman, A and Hardisty, R and Erven, A and Gray, IC and Voeling, S and Isaacs, A and Tsai, H and Strivens, M and Washbourne, R and Thornton, C and Greenaway, S and Hewitt, M and McCormick, S and Selley, R and Wells, C and Tymowska-Lalanne, Z and Roby, P and Mburu, P and Rogers, D and Hagan, J and Reavill, C and Davies, K and Glenister, P and Fisher, EMC and Martin, J and Vizor, L and Bouzyk, M and Kelsell, D and Guenet, JL and Steel, KP and Sheardown, S and Spurr, N and Gray, I and Peters, J and Nolan, PM and Hunter, AJ and Brown, SDM (2004) Towards a mutant map of the mouse - new models of neurological, behavioural, deafness, bone, renal and blood disorders. GENETICA , 122 (1) 47 - 49.

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Robson, JC and Bowen, S and Ball, S and Fisher, EM and Gupta, S and Nickols, C and Parkinson, LC and Peters, J and Martin, JE (2002) Gene dose effects in "Gammy": A mouse model of human club foot. J PATHOL , 198 51A - 51A.

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Rogers, DC and Peters, J and Martin, JE and Ball, S and Nicholson, SJ and Witherden, AS and Hafezparast, M and Latcham, J and Robinson, TL and Quilter, CA and Fisher, EMC (2001) SHIRPA, a protocol for behavioral assessment: validation for longitudinal study of neurological dysfunction in mice. NEUROSCI LETT , 306 (1-2) 89 - 92.

Rohrer, JD and Ahsan, RL and Isaacs, AM and Neilsen, JE and Ostergaard, L and Scahill, R and Warren, JD and Rossor, MN and Fox, NC and Johannsen, P and FReJA-Consortium, (2009) Presymptomatic generalised brain atrophy in frontotemporal dementia caused by CHMP2B mutation. Dement. Geriatr. Cogn. Disord. , 27 182 - 186.

Rohrer, JD and Ahsan, RL and Isaacs, AM and Nielsen, JE and Ostergaard, L and Scahill, R and Warren, JD and Rossor, MN and Fox, NC and Johannsen, P and FReJA Consortium, (2009) Presymptomatic Generalized Brain Atrophy in Frontotemporal Dementia Caused by CHMP2B Mutation. DEMENT GERIATR COGN , 27 (2) 182 - 186. 10.1159/000200466.

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Sheppard, O and Plattner, F and Rubin, A and Slender, A and Linehan, JM and Brandner, S and Tybulewicz, VL and Fisher, EM and Wiseman, FK (2011) Altered regulation of tau phosphorylation in a mouse model of down syndrome aging. Neurobiol Aging , 33 (4) 828.e31-828.e44. 10.1016/j.neurobiolaging.2011.06.025. An open access publication

Sheppard, O and Wiseman, FK and Ruparelia, A and Tybulewicz, VL and Fisher, EM (2012) Mouse models of aneuploidy. ScientificWorldJournal , 2012 214078 - ?. 10.1100/2012/214078. An open access publication

Skibinski, G and Parkinson, NJ and Brown, JM and Chakrabarti, L and Lloyd, SL and Hummerich, H and Nielsen, JE and Hodges, JR and Spillantini, MG and Thusgaard, T and Brandner, S and Brun, A and Rossor, MN and Gade, A and Johannsen, P and Sorensen, SA and Gydesen, S and Fisher, EMC and Collinge, J (2005) Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia. NAT GENET , 37 (8) 806 - 808. 10.1038/ng1609.

Stevens, JC and Banks, GT and Festing, MFW and Fisher, EMC (2007) Quiet mutations in inbred strains of mice. TRENDS MOL MED , 13 (12) 512 - 519. 10.1016/j.molmed.2007.10.001.

Stevens, JC and Chia, R and Hendriks, WT and Bros-Facer, V and van Minnen, J and Martin, JE and Jackson, GS and Greensmith, L and Schiavo, G and Fisher, EMC (2010) Modification of Superoxide Dismutase 1 (SOD1) Properties by a GFP Tag - Implications for Research into Amyotrophic Lateral Sclerosis (ALS). PLOS ONE , 5 (3) , Article e9541. 10.1371/journal.pone.0009541. An open access publication. A version is also available from UCL Discovery.

Stevens, JC and Fisher, EMC and Mead, S (2011) How does the genetic assassin select its neuronal target? MAMM GENOME , 22 (3-4) 139 - 147. 10.1007/s00335-011-9319-5.

Stokholm, J and Teasdale, T and Johannsen, P and Nielsen, J and Nielsen, T and Isaacs, A and Brown, J and Gade, A and The FReJA Consortium, (2013) Cognitive impairment in athe preclinical stage of dementia in FTD-3 CHMP2B mutation carriers: a longitudinal prospective study. Journal of Neurology, Neurosurgery and Psychiatry (84) 170 - 176.

Thorne, T and Fratta, P and Hanna, MG and Cortese, A and Plagnol, V and Fisher, EM and Stumpf, MP (2013) Graphical modelling of molecular networks underlying sporadic inclusion body myositis. Mol Biosyst 10.1039/c3mb25497f.

Tsipouri, V and Curtin, JA and Nolan, PM and Vizor, L and Parsons, CA and Clapham, CM and Latham, ID and Rooke, LJ and Martin, JE and Peters, J and Hunter, AJ and Rogers, D and Rastan, S and Brown, SDM and Fisher, EMC and Spurr, NK and Gray, IC (2004) Three novel pigmentation mutants generated by genome-wide random ENU mutagenesis in the mouse. COMP FUNCT GENOM , 5 (2) 123 - 127. 10.1002/cfg.382. An open access publication

Tsipouri, V and Hough, T and Curtin, JA and Guionaud, S and Fulleylove, M and Vizor, L and Hoult, D and Scheib, H and Brown, SDM and Fisher, EMC and Spurr, NK and Gray, IC (2004) An ENU-induced, low-cholesterol, low-HDL cholesterol mouse mutant carries an Abca1 point mutation and is a model for Tangier disease and familial hypoalphalipoproteinemia. Comparative and Functional Genomics , 5 123 - 127.

Tybulewicz, VLJ and Fisher, EMC (2006) New techniques to understand chromosome dosage: mouse models of aneuploidy. HUM MOL GENET , 15 R103 - R109. 10.1093/hmg/ddl179.

Urwin, H and Authier, A and Nielsen, JE and Metcalf, D and Powell, C and Froud, K and Malcolm, DS and Holm, I and Johannsen, P and Brown, J and Fisher, EMC and van der Zee, J and Bruyland, M and Van Broeckhoven, C and Collinge, J and Brandner, S and Futter, C and Isaacs, AM and FReJA Consortium, (2010) Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations. HUM MOL GENET , 19 (11) 2228 - 2238. 10.1093/hmg/ddq100.

Urwin, H and Josephs, KA and Rohrer, JD and Mackenzie, IR and Neumann, M and Authier, A and Seelaar, H and Van Swieten, JC and Brown, JM and Johannsen, P and Nielsen, JE and Holm, IE and Dickson, DW and Rademakers, R and Graff-Radford, NR and Parisi, JE and Petersen, RC and Hatanpaa, KJ and White, CL and Weiner, MF and Geser, F and Van Deerlin, VM and Trojanowski, JQ and Miller, BL and Seeley, WW and van der Zee, J and Kumar-Singh, S and Engelborghs, S and De Deyn, PP and Van Broeckhoven, C and Bigio, EH and Deng, HX and Halliday, GM and Kril, JJ and Munoz, DG and Mann, DM and Pickering-Brown, SM and Doodeman, V and Adamson, G and Ghazi-Noori, S and Fisher, EMC and Holton, JL and Revesz, T and Rossor, MN and Collinge, J and Mead, S and Isaacs, AM and FReJA Consortium, (2010) FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration. ACTA NEUROPATHOL , 120 (1) 33 - 41. 10.1007/s00401-010-0698-6.

van de Leemput, J and Chandran, J and Knight, MA and Holtzclaw, LA and Scholz, S and Cookson, MR and Houlden, H and Gwinn-Hardy, K and Fung, HC and Lin, X and Hernandez, D and Simon-Sanchez, J and Wood, NW and Giunti, P and Rafferty, I and Hardy, J and Storey, E and Gardner, RJM and Forrest, SM and Fisher, EMC and Russell, JT and Cai, H and Singleton, AB (2007) Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans. PLOS GENET , 3 (6) , Article e108. 10.1371/journal.pgen.0030108. An open access publication

van de Leemput, J and Wavrant-De Vrieze, F and Rafferty, I and Bras, JM and Giunti, P and Fisher, EMC and Hardy, JA and Singleton, AB and Houlden, H (2010) Sequencing Analysis of the ITPR1 Gene in a Pure Autosomal Dominant Spinocerebellar Ataxia Series. MOVEMENT DISORD , 25 (6) 771 - 773. 10.1002/mds.22970.

van der Zee, J and Urwin, H and Engelborghs, S and Bruyland, M and Vandenberghe, R and Dermaut, B and De Pooter, T and Peeters, K and Santens, P and De Deyn, PP and Fisher, EM and Collinge, J and Isaacs, AM and Van Broeckhoven, C (2008) CHMP2B C-truncating mutations in frontotemporal lobar degeneration are associated with an aberrant endosomal phenotype in vitro. HUM MOL GENET , 17 (2) 313 - 322. 10.1093/hmg/ddm309.

Vidal-Taboada, JM and Bergonon, S and Sanchez, M and Lopez-Acdeo, C and Groet, J and Nizetic, D and Katsanis, N and Fisher, EMC and Delabar, JM and Oliva, R (1998) A 342kb ready-to-sequence PAC and cosmid contig with full EcoRI/SMAI restriction map between markers ACTL5 and D21S268 within the Down syndrome region-2. Biochem. Biophys. Res. Comm. , 243 572 - ?.

Wang, W and Fisher, EMC and Jia, Q and Dunn, JM and Porfiri, E and Downward, J and Egan, SE (1995) The Grb2 binding domain of mSos1 is not required for downstream signal transduction. Nature Genetics , 10 294 - 299.

Wang, Y and Mulligan, C and Denyer, G and Delom, F and Dagna-Bricarelli, F and Tybulewicz, VLJ and Fisher, EMC and Griffiths, WJ and Nizetic, D and Groet, J (2009) Quantitative Proteomics Characterization of a Mouse Embryonic Stem Cell Model of Down Syndrome. MOL CELL PROTEOMICS , 8 (4) 585 - 595. 10.1074/mcp.M800256-MCP200.

Ward, CL and Fisher, EMC and Ball, ST and Peters, J and Martin, JE (1999) Novel mouse mutant with motor dysfunction from phenotype to genotype. J PATHOL , 187 23A - 23A.

Washbourne, R and Nolan, P and Peters, J and Vizor, L and Hewitt, M and Sellley, R and Strivens, M and Martin, J and Fisher, E and Rogers, D and Hagan, J and Spurr, N and Rastan, S and Browne, M and Hunter, J and Brown, S (2000) Identification of novel behavioural mutations using ENU mutagenesis. EUR J NEUROSCI , 12 235 - 235.

Wiggins, LM and Kuta, A and Stevens, JC and Fisher, EMC and von Bartheld, CS (2012) A Novel Phenotype for the Dynein Heavy Chain Mutation Loa: Altered Dendritic Morphology, Organelle Density, and Reduced Numbers of Trigeminal Motoneurons. JOURNAL OF COMPARATIVE NEUROLOGY , 520 (12) 2757 - 2773. 10.1002/cne.23085.

Wills, AM and Cronin, S and Slowik, A and Kasperaviciute, D and Van Es, MA and Morahan, JM and Valdmanis, PN and Meininger, V and Melki, J and Shaw, CE and Rouleau, GA and Fisher, EMC and Shaw, PJ and Morrison, KE and Pamphlett, R and Van den Berg, LH and Figlewicz, DA and Andersen, PM and Al-Chalabi, A and Hardiman, O and Purcell, S and Landers, JE and Brown, RH (2009) A large-scale international meta-analysis of paraoxonase gene polymorphisms in sporadic ALS. NEUROLOGY , 73 (1) 16 - 24. 10.1212/WNL.0b013e3181a18674.

Wilson, MD and Barbosa-Morais, NL and Schmidt, D and Conboy, CM and Vanes, L and Tybulewicz, VLJ and Fisher, EMC and Tavare, S and Odom, DT (2008) Species-specific transcription in mice carrying human chromosome 21. SCIENCE , 322 (5900) 434 - 438. 10.1126/science.1160930.

Wiseman, FK and Alford, KA and Tybulewicz, VLJ and Fisher, EMC (2009) Down syndrome-recent progress and future prospects. HUM MOL GENET , 18 R75 - R83. 10.1093/hmg/ddp010. An open access publication. A version is also available from UCL Discovery.

Wiseman, FK and Sheppard, O and Linehan, JM and Brandner, S and Tybulewicz, VL and Fisher, EM (2010) Generation of a panel of antibodies against proteins encoded on human chromosome 21. J Negat Results Biomed , 9 7 - ?. 10.1186/1477-5751-9-7.

Witherden, AS and Hafezparast, M and Nicholson, SJ and Ahmad-Annuar, A and Bermingham, N and Arac, D and Rankin, J and Iravani, M and Ball, S and Peters, J and Martin, JE and Huntley, D and Hummerich, H and Sergot, M and Fisher, EMC (2002) An integrated genetic, radiation hybrid, physical and transcription map of a region of distal mouse chromosome 12, including an imprinted locus and the 'Legs at odd angles' (Loa) mutation. GENE , 283 (1-2) 71 - 82.

Witherden, AS and Nicholson, SJ and Fisher, EMC (1997) The value of mouse mutants. Mouse Genome , 95 856 - 874.

Yulug, IG and Egan, SE and Pollock, PM and Fisher, EMC (1993) A homologue of the Drosophila Son of Sevenless gene maps to mouse chromosome 17. Genomics , 18 733 - 734.

Yulug, IG and Egan, SE and See, CG and Fisher, EMC (1995) Mapping human SHC, a gene that encodes an adaptor protein and identifying and mapping a SHC related sequence. Hum. Genet. , 96 245 - 248.

Yulug, IG and Egan, SE and See, CG and Fisher, EMC (1994) Mapping GRB2, a signal transduction gene in the human and the mouse. Genomics , 22 313 - 318.

Yulug, IG and Fisher, EMC (1995) The frequency and position of Alu repeats in cDNAs, as determined by database searching. Genomics , 27 544 - 548.

Yulug, IG and Hillermann, R and Fisher, EMC (1994) The SHB adaptor protein maps to human chromosome 9. Genomics , 24 615 - 617.

Yulug, IG and Katsanis, N and de-Belleroche, J and Collinge, J and Fisher, EMC (1995) An improved protocol for the analysis of SOD1 gene mutations, and a new mutation in exon 4. Hum Mol Genet , 4 1101 - 1104.

Yulug, IG and Killary, AM and Sandhu, AK and Athwal, RS and Fox, M and Fisher, EMC (1995) Gene expression in response to retinoic acid in novel human chromosome 21 monochromosomal cell hybrids. SOMAT CELL MOLEC GEN , 21 (5) 357 - 365.

Yulug, IG and See, CG and Fisher, EMC (1995) The DAD1 protein, whose defect causes apoptotic cell death, maps to human chromosome 14. Genomics , 26 433 - 435.

Zinn, AR and Page, DC and Fisher, EMC (1993) Turner syndrome: the case of the missing sex chromosome. Trends Genet , 9 90 - 93.

Book

UNSPECIFIED (Ed). (1998) Methods in Mouse Genetics and Genome Mapping. Academic Press: New York.

UNSPECIFIED (Ed). Enjoy writing your science thesis or dissertation. Imperial College Press: London UK.

Book chapter

Ballabio, A and Brown, SDM and Fisher, EMC (1997) Strategies for disease identification. In: Genome Analysis: A laboratory manual. Cold Spring Harbor Laboratory Press: Cold Spring Harbor.

Fisher, EMC (1994) Genetics, molecular and cell biology. In: Kumar, PJ and Clark, ML, (eds.) Clinical Medicine. Balliere Tindall: London.

Poster

Hough, T and Fisher, EMC and Cheeseman, M and Hunter, J and Brown, SDM (2003) Characterisation and genetics of a mouse model of hypophospatasia. Presented at: 17th International Mouse Genome conference, Braunschweig, Germany.

Hough, T and Fisher, EMC and Cheeseman, M and Hunter, J and Brown, SDM (2003) Characterisation and genetics of a mouse model of hypophospatasia. Presented at: 17th International Mouse Genome conference, Braunschweig, Germany.

Johannsen, P and Gade, A and Brown, J and Chakrabarti, L and Gjedde, A and Gydesen, S and Sorensen, SA and FReJA-Consortium, (2001) Chromosome-3 linked frontotemporal dementia (FTD3) and cerebral blood flow. Presented at: NorAge meeting, Norway.

Johannsen, P and Holm, I and Simon, F and Eskildsen, SF and Rodell, A and Isaacs, AM and Gade, A and Nielsen, J and Ostergard, L and Fisher, EMC and Collinge, J and Brown, J and The-FReJA-Consortium, (2006) New imaging and pathology findings in FTD-3 patients and mutation carriers. Presented at: 5th International Conference on frontotemporal dementias, San Francisco, USA.

Kara, M and Groet, J and Letourneau, A and Guipponi, M and Santoni, F and Bena, F and Bishop, C and Canzonetta, C and Murray, A and Baldo, C and Dagna-Bricarelli, F and Ballard, D and Syndercombe-Court, D and Fusaki, N and Hasegawa, M and The LonDownS Consortium, and Antonarakis, S and Nizetic, D (2013) AN INTACT GENOME, ISOGENIC HIPSC MODEL FROM A MOSAIC DOWN SYNDROME INDIVIDUAL REVEALS NEUROGENESIS AND MITOCHONDRIAL DEFECTS CAUSED BY TRISOMY 21. Presented at: Workshop on Cognition in Down Syndrome - Molecular, Cellular and Behavioral Features and the Promise of Pharmacotherapies, Washington DC, USA.

Lloyd, SE and Onwuazor, ON and Fisher, EMC and Collinge, J (2000) Quantitative trait locus analysis of prion disease incubation time. Presented at: Join Funders Transmissible Spongiform Encephalopathies workshop, Keele, Uk.

Lloyd, SE and Uphill, JB and Targonski, P and Fisher, EMC and Collinge, J (2002) Identification of genetic loci affecting bovine spongiform encephalopathy incubation time in mice. Presented at: Joint Funders Transmissible Spongiform Encephalopathies workshop, Durham.

Massand, E and Karmiloff-Smith, A and The LonDownS Consortium, (2013) Understanding adult outcomes through infancy studies: Neuro-cognitive phenotypes of infants with Down syndrome may predict protective/risk markers for Alzheimer’s disease. Presented at: Workshop on Cognition in Down Syndrome - Molecular, Cellular and Behavioral Features and the Promise of Pharmacotherapies, Washington DC, USA.

Richardson, S and Siow, B and Wells, J and Fisher, EMC and Schiavo, G and Lythgoe, MF (2010) MRI detection of axonal transport via tetanus neurotoxin bound ixide nanoparticles. Presented at: BCISMRM MR Post-Graduate Meeting, Institute of Psychiatry, Kings College London.

Ruparelia, A and Wiseman, F and Sheppard, O and Kuta, A and Tybulewicz, VLJ and Schiavo, G and Fisher, EMC (2010) Axonal transport in a panel of mice that model Down syndrome. Presented at: Queen Square Student Symposium, UCL, Institute of Neurology, UCL, London.

Tybulewicz, VLJ and O'Doherty, A and Wiseman, F and Broughton, T and Ruf, S and Mulligan, C and Morice, E and Cooke, S and Vanes, L and Dunlevy, L and Mohun, T and Sharpe, PT and Brandner, S and Bliss, TVP and Henderson, DJ and Nizetic, D and Fisher, EMC (2007) Characterization of an aneuploid mouse with a human chromosome that models Down syndrome. Presented at: Expert workshop on the biology of chromosome 21 genes: Towrds gene-phenotype correlations in Down syndrome, Washington, DC.

Witherden, AS and Hafezparast, M and Nicholson, SJ and Bermingham, N and Ball, S and Peters, J and Rogers, D and Martin, JE and Fisher, EMC (1999) Mapping of the mouse motor neurodegeneration gene Loa (legs at odd angles) and progress towards its cloning. Presented at: Imperial college School of Medicine Open Day, London, UK.

Zinyuk, LE and Tybulewicz, VLJ and Fisher, EMC and Jones, MW (2009) Understanding higher brain function and complex disorders using rodent models. Presented at: The 3Rs today, NC£Rs poster event, London, UK.

Proceedings paper

Acevedo-Arozena, A and Corrochano, S and Ricketts, T and Carter, S and Ribinsztein, DC and Fisher, EMC and Brown, SDM Sensitised ENU screens for Huntingtons Disease and Amyotrophic Lateral Sclerosis. In: (Proceedings) Society for Neuroscience meeting 2009.

Acevedo-Arozena, A and Ricketts, T and Kalmar, B and Kent, R and Greensmith, L and Fisher, EMC A mutagenesis strategy to find SOD1 ALS modifiers in the mouse. In: (Proceedings) 20th International Symposium on ALS/MND.

Acevedo-Arozena, A and Ricketts, T and Kalmar, B and Kent, R and Greensmith, L and Fisher, EMC Using ENU mutagenesis to search for modifiers of SOD1 ALS in the mouse. In: (Proceedings) 20th International Symposium on ALS/MND.

Acevedo-Arozena, A and Rowe, C and Fisher, EMC A mutagenesis strategy to find SOD1 ALS modifiers in the mouse. In: (Proceedings) 6th FENS forum for European Neuroscientists.

Acevedo-Arozena, A and Rowe, C and Fisher, EMC Searching for SOD1 ALS modifiers in the mouse. In: (Proceedings) International Mammalian Genome Conference.

Achilli, F and Boyle, S and Kieran, D and Chia, R and Hafezparast, M and Martin, JE and Schiavo, G and Greensmith, L and Bickmore, W and Fisher, EMC (2005) The SOD1 transgene in the G93A mouse model of amyotrophic lateral sclerosis lies on distal mouse chromosome 12. In: ALS and Other MNDs.

Achilli, F and Nolan, P and Fisher, EMC Characterisation of new mice models of motor neuron disease. In: (Proceedings) 18th International Mouse Genome Conference.

Achilli, F and Nolan, P and Lalanne, Z and Hardy, A and Booker, D and Strand, K and Revesz, T and Fisher, EMC Characterisation of new locomotor mutants. In: (Proceedings) 19th International Mouse Genome Conference.

Ahmad-Annuar, A and Hafezparast, M and Witherden, A and Ball, S and Hummerich, H and Peters, J and Martin, JE and Fisher, EMC Legs at odd angles: a mouse mutant for motor neuron degeneration. In: (Proceedings) Fourth Workshop on Mouse Molecular Genetics.

Ahmad-Annuar, A and Hafezparast, M and Witherden, A and Ball, S and Peters, J and Martin, JE and Fisher, EMC Legs at odd angles: a mouse mutant with a neuronal deficit. In: (Proceedings) 15th International Mouse Genome conference.

Ahmad-Annuar, A and Shah, P and Hafezparast, M and Goldstein, D and Fisher, EMC Linkage disequilibrium and haplotype mapping of the human cytoplasmic dynein heavy chain 1 gene. In: (Proceedings) Graduate School of Life Sciences and Medicine Student Symposium, Imperial College.

Ahmad-Annuar, A and Shah, P and Hafezparast, M and Goldstein, DB and Fisher, EMC (2003) Linkage disequilibrium and haplotype mapping of the human cytoplasmic dynein heavy chain 1 gene on chromosome 14q32. In: AMERICAN JOURNAL OF HUMAN GENETICS. (pp. 487 - 487). UNIV CHICAGO PRESS

Airey, J and Washbourne, R and Peters, J and Vizor, L and Tymowska-Lalanne, Z and Smythe, S and Martin, J and Fisher, EMC and Rogers, D and Hagan, J and Rastan, S and Browne, M and Hunter, J and Brown, S and Nolan, PM Analysis of ENU-induced mutations exhibiting an elevated acoustic startle response. In: (Proceedings) 15th International Mouse Genome conference.

Alford, KA and Vanes, L and Fisher, EMC and Tybulewicz, VLJ A myeloproliferative disorder in the Tc1 mouse model of Down syndrome. In: (Proceedings) Modern trends in human leukemia, Wilsede Meeting XV11.

Alford, KA and Vanes, L and Li, Z and Orkin, SH and Fisher, EMC and Tybulewicz, VLJ (2008) A Myeloproliferative Disorder in the Tel Mouse Model of Down Syndrome. In: BLOOD. (pp. 964 - 964). AMER SOC HEMATOLOGY

Ali-Morsi, A and Stoddart, E and Bros-Facer, V and Fisher, EMC and Greensmith, L and Hafezparast, M Investigating why dynein mutation ameliorates the SOD1 ALS phenotype and considerably extends lifespan. In:

AlQatari, M and Vastani, N and Bros-Facer, V and Groves, M and Greensmith, L and Fisher, EM and Koltzenburg, M (2009) A MUTATION OF THE CYTOPLASMIC DYNEIN HEAVY CHAIN GENE Dync1h1 CAUSES A SEVERE SENSORY NEUROPATHY. In: JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM. (pp. 6 - 6). WILEY-BLACKWELL PUBLISHING, INC

Ateh, DD and Hussain, I and Mustafa, A and Price, KM and Nickols, CD and Bird, MM and Greensmith, L and Schiavo, G and Hafezparast, M and Fisher, EMC and Baker, CS and Martin, JE (2006) Normal subcellular distribution of dynein-dynactin complex subunits and disturbances in neurodegenerative disease. In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. (pp. 234 - 235). BLACKWELL PUBLISHING

Ateh, DD and Hussain, I and Mustafa, A and Price, KM and Nickols, CD and Bird, MM and Greensmith, L and Schiavo, G and Hafezparast, M and Fisher, EMC and Baker, CS and Martin, JE (2006) Subcellular functional specificity of dynein-dynactin complex subunits - normal distribution and disturbances in neurodegenerative disease. In: JOURNAL OF PATHOLOGY. (pp. 23A - 23A). JOHN WILEY & SONS LTD

Baker, CS and Price, KM and Bowen, S and Hafezparast, M and Ahmad-Annuar, A and Peters, J and Fisher, EMC and Martin, JE Protein studies of the Loa mutant. In: (Proceedings) 13th International Symposium on ALS/MND.

Baker, CS and Price, KM and Bowen, S and Walker, KE and Chana, S and Fisher, EMC and Martin, JE (2003) Protein characterisation of the Loa mouse. In: Amyotroph. Lateral Scler Other Motor Neuron Disord. (pp. 5 - 227).

Banks, G and Fisher, EMC A functional dissection of the dynein complex by genetic screening in mice. In: (Proceedings) EMBO/FEBS Workshop on Systems Dynamics of Intracellular Communications.

Banks, G and Kuta, A and Bros-Facer, V and Schiavo, G and Koltzenburg, M and Greensmith, L and Fisher, EMC Working with mouse mutants to uncover the roles of transport proteins. In: (Proceedings) EMBO Conference on spatial dynamics of intracellular communication - overcoming distance in signalling networks.

Bermingham, N and Martin, JE and Fisher, EMC Fine mapping the MND locus and mouse chromosome 8. In: (Proceedings) Mouse Molecular Genetics Meeting.

Bermingham, N and Peters, J and Martin, JE and Fisher, EMC Characterisation of three new mouse mutants with neuromuscular deficits. In: (Proceedings) Mouse Molecular Neurogenetics Meeting.

Bermingham, N and Peters, J and Martin, JE and Fisher, EMC Positional cloning of legs at odd angles (Loa). In: (Proceedings) Ninth Mouse Genome meeting.

Bermingham, N and Peters, J and Rogers, D and Martin, J and Fisher, EMC Positional cloning of the neurological mutant: Legs at odd angles (Loa). In: (Proceedings) Second Mouse Molecular Neurogenetics Meeting.

Bermingham, N and Peters, J and Rogers, D and Martin, J and Fisher, EMC The neurological mutant: legs at odd angles (Loa). In: (Proceedings) 10th International Mouse Genome Conference.

Bowen, S and Bird, MM and Deinhardt, K and Price, KM and Baker, CS and Robson, JC and Swash, M and Shamsuddin, W and Kawar, S and Hoyle, A and El-Tawil, T and Hazarika, R and Nickols, C and Knowles, CH and Pullen, AH and Luthert, PJ and Weller, RO and Hafezparast, M and Franklin, R and Revesz, T and King, RHM and Fisher, EMC and Schiavo, G and Martin, JE Phagocytosis of cell and non-cell debris by neurons in vitro and in vivo. In: (Proceedings) 15th International ALS symposium.

Bros, V and Golding, M and Chia, R and Schiavo, G and Flenniken, A and Adamson, SL and Rossant, J and Fisher, EMC and Greensmith, L and Hafezparast, M The Arl mouse - a new mouse strain with a mutation in the cytoplasmic dynein heavy chain. In: (Proceedings) Mutant SOD1 and ALS: from the molecule to man.

Bros, V and Golding, M and Schiavo, G and Chia, R and Philpott, A and Flenniken, A and Adamson, SL and Rossant, J and Greensmith, L and Fisher, EMC and Hafezparast, M The Arl mouse - a new mouse strain with a mutation in the cytoplasmic dynein heavy chain. In: (Proceedings) EMBO/FEBS Workshop on Systems Dynamics of Intracellular Communications.

Bros-Facer, V and Baisland, L and Hafezparast, M and Fisher, EMC and Duchen, M and Schiavo, G and Greensmith, L The effects of a dynein mutation on mitochondria in SOD1 motoneurons. In: (Proceedings) 19th International Symposium on ALS/MND.

Bros-Facer, V and Banks, GT and Williams, H and Greensmith, L and Fisher, EMC A novel mutation in glycine tRNA synthetase ameliorates SOD1G93A motor neuron degeneration. In: (Proceedings) 19th International Symposium on ALS/MND.

Brown, J and Gydesen, S and Johannsen, P and Gade, A and Skinbinski, G and Chakrabarti, L and Brun, A and Spillantini, M and Yancopoulou, D and Thusgaard, T and Sorensen, A and Fisher, EMC and Collinge, J Frontotemporal dementia linked to chromosome 3 (FTD3). In: (Proceedings) 14th International Conference on Frontotemporal Dementia.

Brown, J and The-FReJA-Consortium, Clinical features of frontotemporal demential linked to chromosome 3 - FTD3. In: (Proceedings) 4th International Conference on Frontotemporal Dementia.

Brown, JM and Isaacs, A and Neilsen, J and The-FReJA-Consortium, Mutations in the endosomal ESCRT-III complex in frontotemporal dementia. In: Alzheimer's & Dementia. (pp. S419 - S419).

Brown, S and Peters, J and Nolan, P and Vizor, L and Thornton, C and Glenister, P and Greenaway, S and Hewitt, M and Selley, R and Strivens, M and Martin, J and Fisher, EMC and Rogers, D and Hagan, J and Rastan, S and Browne, M and Hunter, J A comprehensive ENU mutagenesis programme for the mouse genome. In: (Proceedings) Mouse molecular genetics.

Brown, S and Peters, J and Vizor, L and Thornton, C and Glenister, P and Greenaway, S and Hewitt, M and Selley, R and Strivens, M and Nolan, P and Martin, J and Fisher, EMC and Rogers, D and Hagan, J and Spurr, N and Rastan, S and Browne, M and Hunter, J Evaluation of neurological mouse mutants caused by ENU mutagenesis. In: (Proceedings) EMBL Mouse Molecular Genetics Meeting.

Brown, S and Peters, J and Vizor, L and Thornton, C and Glenister, P and Greenaway, S and Hewitt, M and Selley, R and Strivens, M and Nolan, P and Martin, J and Fisher, EMC and Rogers, D and Hagan, J and Spurr, N and Rastan, S and Browne, M and Hunter, J The mutant map of the mouse. In: (Proceedings) Genome Sequencing and Biology Meeting.

Brown, S and Peters, J and Vizor, L and Thornton, C and Glenister, P and Greenaway, S and Nolan, P and Hewitt, M and Selley, R and Strivens, M and Martin, J and Fisher, EMC and Rogers, D and Hagan, J and Rastan, S and Browne, M and Hunter, J A comprehensive ENU mutagenesis programme for the mouse genome. In: Cytogenetics and Cell Genetics.

Brun, A and The-FReJA-Consortium, Pathology of FTD3. In: (Proceedings) International Conference on Frontotemporal Dementia.

Bunton-Stasyshyn, R and Devoy, A and Fisher, EMC An investigation into the role of endogenousmouse Sod1 in the disease course of transgenic SOD1mouse models of amyotrophic lateral sclerosis. In: (Proceedings) American Society of Neuroscience Annual meeting.

Bunton-Stasyshyn, R and Devoy, A and Tybulewicz, V A SOD1 humanising knock-in mouse model fo ALS with conditional point mutation. In: (Proceedings) Queen Square Student Symposium.

Bunton-Stasyshyn, R and Devoy, A and Tybulewicz, V and Fisher, EMC A SOD1 humanising knock-in mouse model fo ALS with conditional point mutation. In: (Proceedings) Queen Square Student Symposium.

Bunton-Stasyshyn, R and Devoy, A and Tybulewicz, V and Fisher, EMC A SOD1 humanising knock-in mouse model of ALS with conditional point mutation. In: (Proceedings) UCL Neuroscience Symposium.

Bunton-Stasyshyn, R and Devoy, A and Tybulewicz, VLJ and Fisher, EMC A SOD1 humansing knock-in mouse model of ALS with conditional point mutation. In: (Proceedings) Mouse Genetics 2011 Conference.

Chakrabarti, L and Association, FFRIJ Clinical and molecular characterisation of Frontotemporal dementia linked to Human Chromosome 2. In: (Proceedings) American Society of Human Genetics.

Chia, R and Achilli, F and Festing, MFW and Fisher, EMC (2005) The origins and uses of mouse outbred stocks. In: ALS and Other MNDs.

Chia, R and Achilli, F and Festing, MFW and Fisher, EMC The origins and uses of mouse outbred stocks. In: (Proceedings) 19th International Mouse Genome Conference.

Chia, R and Tattum, H and Clarke, A and Fisher, EMC and Jackson, GS In vitro fibrillization of superoxide dismutatse type 1 (SOD1) suggests one possible mechanism by which mutations may lead to amyotrophic lateral sclerosis (ALS). In: (Proceedings) Keystone symposium: Molecular mechanisms of neurodegeneration.

Choong, X and Raha, A and Tybulewicz, V and Wiseman, F and Fisher, EMC (2013) Identification of genes on Hsa21 influencing APP/A pathology using primary neuronal cultures from transgenic mice. In: (Proceedings) British Neuroscience Association.

Choong, X and Raha, A and Tybulewicz, V and Wiseman, F and Fisher, EMC (2013) Using primary neurons from transgenic mice to identify genes on human chromosome 21 influencing Alzheimer neuropathology. In: (Proceedings) Alzheimer Association International Conference.

Choong, X and Raha, A and Tybulewicz, V and Wiseman, F and Fisher, EMC (2013) Which genes on human chromosome 21, other than APP, influence Alzheimer neuropathology? In: (Proceedings) Alzheimers Research UK Annual Conference.

Cleary, J and Price, A and Thayyil, S and Schambler, P and Tybulewicz, VLJ and Fisher, EMC and Taylor, A and Ordidge, R and Lythgoe, M Towards 3D virtual histology using high-field magnetic resonance imaging. In: (Proceedings) British Association of Clinical Anatomists.

Cleary, JO and Norris, FC and Wiseman, FK and Price, AN and Choy, MK and Tybulewicz, VLJ and Ordidge, RJ and Fisher, EMC and Lythgoe, MF Optimised μMRI for Phenotyping the Tc1 Model of Down Syndrome. In: (Proceedings) Society for Magnetic Resonance in Medicine.

Cooke, SF and Errington, ML and O'Doherty, A and Sesay, A and Ruf, A and Vanes, L and Bliss, TVP and Tybulewicz, VLJ and Fisher, EMC Insertion of human chromosome 21 into the mouse genome leads to impairments of hippocampal LTP and memory. In: (Proceedings) Society for Neuroscience.

Crawford, H and Wiseman, F and Fisher, EMC and Pocock, J (2013) Clues to Down syndrome and Alzheimer’s disease: investigating microglial behaviour in the Tc1 mouse model. In: (Proceedings) UCL ION Student Symposium.

Curtin, JA and Tsipouri, V and Latham, I and Nolan, P and Hardisty, R and Vizor, L and Sims, MA and Parsons, C and Martin, J and Rooke, LJ and Rastan, S and Hunter, AJ and Brown, S and Fisher, EMC Rapid genome scan reveals linkage to mouse chromosome 15 for the ENU induced circling mouse mutant spin cycle, a potential model for DFNA17. In: (Proceedings) Mouse Initiatives III: Modeling the Human Genome & Disease.

Curtin, JA and Tsipouri, V and Latham, I and Nolan, P and Hardisty, R and Vizor, L and Sims, MA and Parsons, C and Naase, MA and Doncaster, K and Rastan, S and Hunter, AJ and Brown, S and Fisher, EMC and Gray, IC and Spur, NK (2001) Rapid genome scan reveals linkage to chromosome 15 for the ENU induced circling mouse mutant, spin cycle. In: Copp, AJ and Fisher, EMC, (eds.) Genetcis Research. (pp. 203 - ?). Cambridge Journals

Delabar, JM and Creau, N and Antonarakis, SE and Brahe, C and Estivill, X and Pritchard, M and Fisher, EMC and Kessling, A and Yaspo, ML and Lehrach, H and Nizetic, D and Oliva, R and Petersen, M and Potier, MC and Roizes, G and Van-Broeckhoven, C and Lutfalla, G (1996) Towards an integrated chromosome 21 map: progress of the European chromosome 21 consortium. In: European Journal of Human Genetics.

Delabar, JM and Creau, N and Brahe, C and Fisher, EMC and Kessling, A and Potier, MC and Nizetic, D and Petersen, MB and Van-Broeckhoven, C European chromosome 21 consortium: two years achievements. In: European Journal of Human Genetics.

Devoy, A and Bunton-Stasyshyn, R and Tybulewicz, VLJ and Fisher, EMC Making new mouse models of ALS. In: (Proceedings) 22nd International Symposium on ALS/MND.

Devoy, A and Fratta, P and Fisher, EMC Making new mouse models of ALS. In: (Proceedings) MRC Centre for Translational Research - Scientific Advisory Board Review.

Devoy, A and Tybulewicz, VLJ and Fisher, EMC A SOD1 humansing knock-in mouse model of ALS with conditional point mutation. In: (Proceedings) Mouse Genetics 2011 Conference.

Dunlevey, LPE and Fisher, EMC and Tybulewicz, VLJ and Mohun, T Cardiac development in a mouse model of Down Syndrome (Tc1). In: (Proceedings) ESC WG Developmental Anatomy and Pathology meeting 2009.

Dunlevey, LPE and Fisher, EMC and Tybulewicz, VLJ and Mohun, T Cardiac development in a mouse model of Down syndrome (Tc1). In: (Proceedings) First AnEUploidy Workshop.

Dunlevy, L and Fisher, EMC and Tybulewicz, VLJ and Mohun, T Cardiac development in a mouse model of Down Syndrome (Tc1). In: (Proceedings) Weinstein Cardiovascular Development Conference.

Egan, SE and Fisher, EMC and Downward, J (1994) Transformation by the mSos1 Ras exchange protein. In: J. Cell. Biochem. (pp. 234 - ?).

Errington, ML and Cooke, SF and O'Doherty, A and Ruf, S and Vanes, L and Bliss, TVP and Tybulewicz, VLJ and Fisher, EMC Insertion of human chromosome 21 into the mouse genome leads to impairments of memory and hippocampal LTP. In: (Proceedings) British Neuroscience Association.

Farrer, MH and Prasher, VP and Fisher, EMC and Kessling, AM Phenotype/genotype mapping Alzheimer-type dementia in Down syndrome. In: American Journal of Human Genetics. (pp. 500 - ?).

Farrer, MJ and Fisher, EMC and Kessling, AM Molecular genetic characterisation of six cases with partial chromosome 21 aneuploidy. In: European Journal of Human Genetics (Supp).

Fisher, EMC Multiple mouse models for helping us understand ALS. In: (Proceedings) 2nd European ALS Research Workshop.

Fisher, EMC The genetics of motor neurone disorders. In: (Proceedings) NIGMS Research Symposium Minority program..

Fisher, EMC Treating hybrid cell lines with retinoic acid. In: (Proceedings) Gordon Research Conference on Developmental Biology.

Fisher, EMC and Alford, K and Dunlevy, L and Lana-Elola, E and Haas, M and Line, S and Reynolds, L and Ruparelia, A and Sheppard, O and Watson, S and Wiseman, F and Zynuk, L and Bennerman, D and Guillemot, F and Hodivala-Dilke, K and Jones, M and Mohun, T and Tybulewicz, VLJ Recent data on the phenotype of the Tc1 mouse model of Down syndrome. In: (Proceedings) 2nd Aneuploidy Workshop.

Fisher, EMC and Brown, LG and Page, DC Mapping the human Y chromosome. In: (Proceedings) Gordon Research Conference on Mammalian Gametogenesis and Embryogenesis.

Fisher, EMC and Bunton-Stasyshyn, R and Devoy, A and Tybulewicz, V A SOD1 humanising knock-in mouse model of ALS with conditional point mutation. In: (Proceedings) Mouse Genetics 2011 Conference.

Fisher, EMC and Cavanna, J and Brown, SDM Microdissection of the mouse X chromosome. In: (Proceedings) International Society of Differentiation, Differentiation of Normal and Neoplastic Cells.

Fisher, EMC and Cavanna, J and Brown, SDM Microdissection of the mouse X chromosome. In: (Proceedings) 5th Tenovus Symposium on Eukaryotic genes.

Fisher, EMC and Cavanna, J and Brown, SDM Microdissection of the mouse X chromosome. In: (Proceedings) Fourth International Workshop on Mouse Molecular Genetics.

Fisher, EMC and Cavanna, J and Brown, SDM Microdissection of the mouse X chromosome. In: (Proceedings) EMBO/EMBL Molecular Approaches to Stem Cell Differentiation and Mouse Development.

Fisher, EMC and Cavanna, J and Brown, SDM Microdissection of the mouse X chromosome. In: (Proceedings) Mammalian Genetics Group/Mammalian Biochemical Genetics Group Conference.

Fisher, EMC and Cleary, JO and Norris, FC and Wiseman, FK and Price, AN and Choy, MK and Tybulewicz, VLJ and Ordidge, RJ and Lythgoe, MF Optimised µMRI for Phenotyping the Tc1 Model of Down Syndrome. In: (Proceedings) Society for Magnetic Resonance in Medicine.

Fisher, EMC and Collins, T and Sheppard, O and Fratta, P and Devoy, A (2013) Working with mice to help understand motor neuron disease. In: (Proceedings) National Hospital for Neurology and Neurosurgery. MND open day.

Fisher, EMC and Fratta, P and Joyce, P and Ricketts, T and Acevedo, A Investigating specific transcriptomes in mouse models of amyotrophic lateral sclerosis. In: (Proceedings) EMBO Workshop on Intracellular RNA Localisation and localised translation.

Fisher, EMC and Greenfield, A and Cavanna, J and Brown, SDM Microdissection of mammalian chromosomes. In: (Proceedings) International Chromosome meeting.

Fisher, EMC and Greenfield, A and Cavanna, J and Brown, SDM Microdissection of mammalian chromosomes. In: (Proceedings) Mammalian Genetics Group/Mammalian Biochemical Genetics Group Conference.

Fisher, EMC and Greenfield, A and Cavanna, J and Brown, SDM Microdissection of the mouse X chromosome. In: (Proceedings) Genetical Society Symposium on Molecular Genetics of Animal Development.

Fisher, EMC and Greenfield, A and Cavanna, J and Brown, SDM Microdissection of the mouse X chromosome. In: (Proceedings) Mammalian Genetics Group/Mammalian Biochemical Genetics Group conference.

Fisher, EMC and Greensmith, L Investigating why dynein mutation ameliorates the SOD1 ALS phenotype and considerably extends lifespan. In: (Proceedings) 5th Annual Packard Center for ALS Research Symposium.

Fisher, EMC and Grimmett, W and Johnstone, K and McKie, J and O'Donnell, H and Pollock, P and Yulug, IG and Scambler, PJ Transferring subchromosomal fragments into mouse embryonic carcinoma and stem cells. In: (Proceedings) Mammalian Neurobiology Workshop.

Fisher, EMC and Grimmett, WJ and Johnstone, K and McKie, J and Pollock, PM and Strutt, P and Yulug, IG A PCR approach to cloning genes from Chromosome 21. In: (Proceedings) 3rd International Workshop on Human Chromosome 21.

Fisher, EMC and Hafezparast, M and Ahmad-Annuar, A and Shah, P and Martin, JE Models of motor neuron degeneration. In: (Proceedings) 13th International Symposium on ALS/MND.

Fisher, EMC and Johnstone, K and McKie, J and Scambler, PJ Cell hybrids to isolate genes from human chromosome 21. In: (Proceedings) International Workshop on Chromosome 21..

Fisher, EMC and Joyce, P and Ricketts, T and Fratta, P and Greensmith, L and Acevedo, A (2010) A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: (Proceedings) 21st International Symposium on ALS/MND.

Fisher, EMC and Martin, JE (1997) Phenotypic and genotypic characterisation of feeble. In: Neuropathology and Applied Neuropathology.

Fisher, EMC and McGoldrick, P and Joyce, P and Acevedo, A and Greensmith, L Investigating new mutant models of MND. In: (Proceedings) MRC Centre for Neuromuscular Diseases Annual Meeting.

Fisher, EMC and Page, DC Characterising the distal short arm of the human Y chromosome. In: (Proceedings) Gordon Research Conference on Molecular Genetics.

Fisher, EMC and Ricketts, T and Fratta, P and Joyce, P and McGoldrick, P and Kent, R and Line, S and Greensmith, L and Acevedo, A Characterisation of mouse TDP43 point mutations generated by chemical mutagenesis. In: (Proceedings) 6th Brain Research Conference, RNA-Binding proteins in neurological disease.

Fisher, EMC and Ricketts, T and Fratta, P and Joyce, P and McGoldrick, P and Kent, R and Line, S and Greensmith, L and Acevedo, A Characterisation of mouse TDP43 point mutations generated by chemical mutagenesis. In: (Proceedings) American Society of Neuroscience Annual meeting.

Fisher, EMC and Ruparelia, A and Wiseman, F and Sheppard, O and Kuta, A and Tybulewicz, VLJ and Schiavo, G Axonal transport in a panel of mice that model Down syndrome. In: (Proceedings) Queen Square student symposium, UCL Institute of Neurology.

Fisher, EMC and Sheppard, O and Plattner, F and Rubin, A and Slender, A and Tybulewicz, V International Conference Jerome Lejeune. In: (Proceedings) International Conference Jerome Lejeune.

Fisher, EMC and Sheppard, O and Plattner, F and Rubin, A and Tybulewicz, V and Wiseman, F Trisomy of DYRK1A and phosphorylation of tau in a mouse model of Down syndrome. In: (Proceedings) British Neuroscience Association Symposium 'Neurodevelopmental Disorders Across the Lifespan'.

Fisher, EMC and Watson-Scales, S and Lana-Elola, E and Tybulewicz, V Using chromosome engineering to identify phenotype to genotype relationships in Down syndrome. In: (Proceedings) Mouse Neurological and Behavioural Forum 3.

Fisher, EMC and Wiseman, F and Sheppard, O and Barkus, C and Pettingill, P and Ruparelia, A and Slender, A and Bannerman, D and Tybulewicz, V The role of trisomy of human chromosome 21 in the development of Alzheimer’s disease. In: (Proceedings) International Conference Jerome Lejeune.

Fisher, EMC and Wiseman, F and Sheppard, O and Barkus, C and Pettingill, P and Ruparelia, A and Slender, A and Bannerman, D and Tybulewicz, V The role of trisomy of human chromosome 21 in the development of Alzheimer’s disease. In: (Proceedings) 12th Annual Alzherimer’s Research Trust Network Conference.

Fisher, EMC and Wiseman, F and Tybulewicz, V (2013) Mouse models to understand Down syndrome and Alzheimer disease. In: (Proceedings) Dementia in Intellectual Disability, London Down Syndrome Interest Group meeting.

Fraham-Falkenbert, S and Johannsen, P and Law, I and Jennum, P and Isaacs, A and Brown, J and FReJA, and Neilsen, J changes in regional cerebral glucose metabolism in early symptomatic frontotemporal dementia linked to chromosome 3 (FTD3). In: (Proceedings) Danish Neurological Society meeting.

Fraham-Falkenbert, S and Johannsen, P and Law, I and Jennum, P and Isaacs, A and Brown, J and FReJA Collaboration, and Neilsen, J Changes in regional cerebral glucose metabolism in early symptomatic frontotemporal dementia linked to chromosome 3 (FTD3). In: (Proceedings) Danish Neurological Society meeting.

Fratta, P and Cortese, A and Plagnol, V and Brady, S and Lashley, T and Simone, R and de Silva, R and Greensmith, L and Holton, J and Fisher, EMC and Hanna, M (2013) Alterations in RNA metabolism in sporadic inclusion body myositis. In: (Proceedings) Association of British Neurologists meeting.

Gade, A and Skibinski, G and Gydesen, S and FReJA-Consortium, Preclinical signs of impairment in persons at high risk of frontotemporal dementia related to chromosome 3 (FTD3): preliminary findings in neuropsychological tests. In: (Proceedings) 9th International conference on Alzheimer's disease and related disorders.

Gade, A and The-FReJA-Consortium, FTD3 neuropsychology. In: (Proceedings) 4th International Conference on Frontotemporal Dementia.

Gade, S and Brown, J and Chakrabarti, L and Johannsen, P and Gydesen, S and Association, FFRIJ Chromosome 3 frontotemporal dementia (FTD-3): clinical course and neuropsychology. In: (Proceedings) International Neuropsychological Society.

Galante, M and Jani, H and Vanes, L and Daniel, H and Fisher, EMC and Tybulewicz, VLJ and Bliss, TVP and Morice, E Analysis of cerebellar function in the Tc1 mouse model of Down syndrome. In: (Proceedings) Synaptic plasticity and repair.

Ghazi-Noori, S and Houghton, R and Fisher, EMC and Collinge, J and Asante, EA and Isaacs, AM Phenotypic characterization of CHMP2B knockout mice. In: (Proceedings) 6th International Conference on Frontotemporal Dementias.

Ghazi-Noori, S and Stanczak-Mrozek, K and Smidak, M and Powell, C and O'Malley, C and Linehan, JM and Fisher, EMC and Brandner, S and Collinge, J and Asante, EA and Isaacs, AM Phenotypic characterisation of Chmp2b knock out mice. In: (Proceedings) Society for Neuroscience meeting 2009.

Gray, IC and Nolan, PM and Peters, J and Strivens, M and Hough, T and Vizor, L and Glenister, P and Tymowska-Lalanne, Z and Roby, P and Latham, ID and Doncaster, KE and Parsons, CA and Tsipouri, V and Curtin, JA and Sims, MA and Isaacs, AM and Davies, KE and Rogers, DC and Hagan, J and Fisher, EMC and Martin, J and Spurr, NK and Rastan, S and Hunter, AJ and Brown, SDM New mouse models of human disease. In: (Proceedings) Asia Pacific HUGO meeting.

Grimmett, WJ and Johnstone, K and McKie, J and Strutt, P and Yulug, IG and Scambler, PJ and Fisher, EMC Cloning genes from chromosome 21. In: European Journal of Human Genetics.

Haas, M and Fisher, E and Tybulewicz, VLJ and Guillemot, F Cortical projection neuron morphology in the Tc1 and Ts1Rhr modele of Down syndrome. In: (Proceedings) 2nd Aneuploidy Workshop.

Haas, M and Fisher, EMC and Tybulewicz, VLJ and Guillemot, F Cortical projection neuron morphology in the Tc1 and Ts1Rhr models of Down syndrome. In: (Proceedings) 2nd Aneuploidy Workshop.

Haas, M and Fisher, EMC and Tybulewicz, VLJ and Guillemot, F Neurogenesis in the developing and adult Tc1 mouse, a model of human Down Syndrome. In: (Proceedings) First AnEUploidy Workshop.

Haas, M and Tybulewicz, VLJ and Fisher, EMC and Guillemot, F Cortical development in the Tc1 mouse: a model of Down Syndrome. In: (Proceedings) ANS/AuPS Annual Meeting Sydney 2010.

Haas, M and Tybulewicz, VLJ and Fisher, EMC and Guillemot, F Cortical neurogenesis in the Tc1 mouse model of Down syndrome. In: (Proceedings) Cortical Development.

Haas, M and Watson-Scales, S and Slender, A and Fisher, EMC and Tybulewicz, V and Guillemot, F (2012) Understanding Down syndrome using the Tc1 mouse model. In: (Proceedings) Australian Neuroscience Society.

Haas, MA and Fisher, EMC and Tybulewicz, VLJ and Guillemot, F (2010) Cortical projection neuron dendrite morphology in the Tc1 mouse model of Down Syndrome. In: INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. (pp. 706 - 706). PERGAMON-ELSEVIER SCIENCE LTD

Hafeparast, M and Nicholson, SJ and Witherden, AS and Bermingham, N and Ball, S and Peters, J and Rogers, DC and Martin, JE and Fisher, EMC Loa (Legs at odd angles) a mouse model of motor neurone dysfuntion: mapping and progress towards isolation of the causal gene. In: (Proceedings) 14th International Mammalian Genome Society.

Hafezparast, M and Ahmad-Annuar, A and Lalli, G and Shima, DT and Schiavo, G and Ball, S and Peters, J and Fisher, EMC and Ruhrberg, C Legs at odd angles - a mutation in dynein that impairs the navigation of motor neurons. In: (Proceedings) Molecular Motors 61st Harden Conference.

Hafezparast, M and Ahmad-Annuar, A and Shah, P and Martin, JE and Fisher, EMC Analysis of the cytoplasmic dynein heavy chain gene, which is mutated in the Loa mouse model of anterior horn cell degeneration. In: Amyotroph. Lateral Scler Other Motor Neuron Disord. (pp. 5 - 227).

Hafezparast, M and Ahmad-Annuar, A and Shah, P and Witherden, AS and Bowen, S and Ball, S and Peters, J and Martin, JE and Fisher, EMC Physical and genetic mapping of Loa: a gene involved in motor neuron degeneration. In: (Proceedings) 16th International Mouse Genome Conference.

Hafezparast, M and Ahmad-Annuar, A and Witherden, A and Martin, JEM and Fisher, EMC What have we learnt from Legs at odd angles - a mouse model of motor neuron degeneration? In: (Proceedings) 12th International symposium on ALS/MND.

Hafezparast, M and Hummerich, H and Fisher, EMC Isolation of the legs at odd angles (Loa) gene in a nutant mouse with motor neuron degeneration. In: (Proceedings) UK Mouse genome sequencing meeting.

Hafezparast, M and Kieran, D and Bohnert, S and Dick, J and Martin, JE and Fisher, EMC and Schiavo, G and Greensmith, L Neurodegeneration as a result of defective retrograde axonal transport. In: (Proceedings) Molecular aspects of ageing, and development, toxicology and neuro-immune communication.

Hafezparast, M and Nicholson, SJ and Witherden, AS and Bermingham, N and Ball, S and Peters, J and Rogers, DC and Martin, JE and Fisher, EMC Loa (Legs at odd angles) a mouse model of motor neurone dysfunction: mapping and progress towrds isolation of the causal gene. In: (Proceedings) 2nd Annual Meeting of the International Behavioural and Neural Genetics Society.

Hafezparast, M and Ruhrberg, C and Ahmad-Annuar, A and Bowen, S and Achilli, F and Lalli, G and Ball, S and Toda, T and Peters, J and Schiavo, G and Shima, D and Martin, JE and Fisher, EMC Mutations in dynein link motor neuron degeneration to defects in retrograde transport. In: (Proceedings) 17th International Mouse Genome Conference.

Hafezparast, M and Ruhrberg, C and Ahmad-Annuar, A and Bowen, S and Lalli, G and Preistley, JV and Takashi, T and Schiavo, G and Shima, DT and Martin, JE and Fisher, EMC Mutations in dynein link motor neuron degeneration to defects in retrograde transport. In: (Proceedings) Molecular Aspects of Neurodegenerative Diseases, Intra-neuronal transport and communication, Euro Conference Series, 2nd Meeting.

Hafezparast, M and Witherden, AS and Nicholson, SJ and Ahmad-Annuar, A and Bermingham, N and Arac, D and Rankin, J and Irvani, M and Hummerich, H and Ball, S and Peters, J and Martin, JE and Huntley, D and Sergot, M and Fisher, EMC A transcription map of distal chromosome 12 encompassing Loa: a gene involved in motor neuron degeneration. In: (Proceedings) 4th workshop on Mouse Molecular Neurogenetics.

Hatcher, JP and Rogers, DC and Nolan, P and Fisher, EMC and Martin, JE and Hunter, AJ Development of SHIRPA to characterise the behavioural phenotype of transgenic and gene-targeted mice. In: (Proceedings) Behavioural phenotyping of mouse mutants.

Hernandez, D and Fisher, EMC and Tybulewicz, V Modelling Down syndrome. In: (Proceedings) Mouse Molecular Genetics meeting.

Hernandez, D and Mee, P and Martin, J and Tybulewicz, V and Fisher, EMC Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21. In: (Proceedings) Genetical Society Meeting.

Hernandez, D and Mee, P and Martin, J and Tybulewicz, V and Fisher, EMC Transchromosomal mouse embyronic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21. In: (Proceedings) HUGO meeting.

Hernandez, D and Tybulewicz, V and Fisher, EMC (1997) Modelling aspects of Down syndrome in mice. In: CYTOGENET CELL GENET. (pp. 29 - 29). KARGER

Hernandez, D and Tybulewicz, V and Fisher, EMC (1994) Modelling Down syndrome in mouse. In: Genetics Research (Camb).

Hernandez, D and Tybulewicz, V and Fisher, EMC Creating as panel of 'transgenomic' mouse embryonic stem cell lines that contain freely segregating portions of human chromosome 21. In: (Proceedings) Gordon Research Conference on Human Molecular Genetics.

Hernandez, D and Tybulewicz, V and Fisher, EMC Modelling aspects of Down syndrome in mice. In: (Proceedings) International Conference on Down Syndrome and Chromosome 21.

Hernandez, D and Tybulewicz, V and Fisher, EMC Modelling down syndrome in mice. In: (Proceedings) 3rd International Workshop on The Genetic Control of Vertebrate Development.

Hernandez, D and Tybulewicz, V and Fisher, EMC Transgenic mouse model for Down syndrome. In: (Proceedings) Models for Development, Developmental Pathology Society Meeting.

Hernandez, D and Tybulewicz, VLJ and Fisher, EMC Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21. In: (Proceedings) Mouse Molecular Genetics Meeting.

Hernandez, D and Tybulwicz, VLJ and Fisher, EMC Creating as panel of 'transgenomic' mouse embryonic stem cell lines that contain freely segregating portions of human chromosome 21. In: (Proceedings) International Chromosome 21 Workshop.

Holm, IE and Englund, E and The-FReJA-Consortium, Ubiquitin positive inclusions in Frontotemporal Dementia linked to chromosome 3 (FTD-3). In: (Proceedings) 16th International Congress on Neuropathology.

Holm, IE and Englund, E and The-FReJA-Consortium, Ubiquitin positive inclusions in Frontotemporal Dementia linked to chromosome 3 (FTD-3). In: (Proceedings) 5th International Conference on Frontotemporal Dementia.

Holmes, H and Powell, N and Well, J and O'Callaghan, J and Colgan, N and Siow, B and Richardson, S and O'Neill, M and Collins, C and Fisher, EMC and Oursellin, S and Lythgoe, M (2013) Tensor-based morphometry as a sensitive biomarker of Alzheimer’s disease neuropathology in a Tau transgenic mouse (Tg4510). In: (Proceedings) International Society for Magnetic Resonance in Medicine.

Holmes, H and Wells, J and O'Callaghan, J and Richardson, S and Siow, B and Powell, N and Da, M and Modat, M and Colgan, N and Oursellin, S and Fisher, EMC and Lythgoe, M (2012) Morphometric genomics: in vivo midro MRI for 3D structural imaging of transgenic mice. In: (Proceedings) International Society for Magnetic Resonance in Medicine British Chapter.

Holmes, H and Wells, J and O'Callaghan, J and Richardson, S and Siow, B and Powell, N and Ma, D and Modat, M and Colgan, N and Oursellin, S and Fisher, EMC and Lythgoe, M (2013) Morphometric Genomics: in vivo microMRI for 3D structural imaging of transgenic mice. In: (Proceedings) International Society for Magnetic Resonance in Medicine.

Holmes, H and Wells, J and Siow, B and O'Callaghan, J and Richardson, S and Oursellin, S and Powell, N and Da, M and Fisher, EMC and Lythgoe, MF Optimisation of the inv vivo sequence for structural imaging of a mouse model of Alsheimer disease. In: (Proceedings) The International Society for Magnetic Resonance in Medicine.

Hough, T and Fisher, E and Cheeseman, M and Hunter, J and Brown, SDM (2004) Characterization and genetics of a mouse model of hypophosphatasia. In: GENETICAL RESEARCH. (pp. 120 - 121). CAMBRIDGE UNIV PRESS

Hough, T and Fisher, EMC and Cheeseman, M and Hunter, AJ and Brown, SDM Characterisation of mouse lines with abnormal levels of plasma alkaline phosphatase. In: (Proceedings) MRC Mammalian Genetics Unit Retreat.

Hough, T and Gray, IC and Nolan, PM and Peters, J and Fisher, EMC and Martin, J and Browne, M and Vizor, L and Bouzyk, M and Kelsell, D and Hunter, AJ and Brown, SDM and Rastan, S Towards a mutant map of the mouse - new mutant models for bone, renal failure and blood lipids. In: (Proceedings) Mutagenesis Meeting.

Hough, T and Hunter, AJ and Nolan, PM and Tsipouri, V and Goldsworthy, M and Moir, L and Toye, A and Vizor, L and Gray, IC and Peters, J and Fisher, EMC and Rastan, S and Martin, J and Spurr, NK and Cox, R and Brown, SDM Novel phenotypes identified by plasma biochemical screening in the mouse. In: (Proceedings) 15th International Mouse Genome conference.

Hough, T and Nolan, P and Tsipouri, V and Toye, A and Goldsworthy, M and Moir, L and Vizor, L and Cox, RD and Gray, I and Peters, J and Spurr, N and Rastan, S and Martin, J and Fisher, EMC and Hunter, AJ and Brown, SDM Mouse models of human metabolic disorders - characterisation of mutant lines with abnormal levels of plasma alkaline phosphatase. In: (Proceedings) 16th International Mouse Genome Conference.

Hough, T and Nolan, PM and Peters, J and Fisher, EMC and Martin, J and Browne, M and Rastan, S and Vizor, L and Brown, SDM and Hunter, AJ Clinical biochemistry screens can complement behavioural screens in mutagenised mice. In: (Proceedings) 2nd Annual Meeting of International Behavioural and Neural Genetics Society.

Hoyle, J and Smith, DJ and Connolly, JAC and Fisher, EMC (1995) Characterisation of the S4 gene, a member of a highly conserved gene family involved in ubiquitinated degradation of proteins. In: Genetics Research (Camb).

Hoyle, J and Smith, DJ and Fisher, EMC Characterisation of the S4 gene in mouse and human. In: (Proceedings) 1st conference on the AAA family of ATPases.

Hoyle, J and Smith, DJ and Fisher, EMC Characterisation of the S4 gene, a member of a highly conserved gene family involved in the ubiquitin protein degradation pathway. In: (Proceedings) Developmental Biology - Gordon Research Conference.

Hoyle, J and Wilkinson, D and Fisher, EMC Expression of the mouse P26S4 gene, an ATPase regulatory subunit of the 26S proteosome. In: (Proceedings) Gordon Research Conference: Molecular Genetics.

Hunter, AJ and Hagan, JJ and Rogers, D and Nolan, P and Strivens, M and Peters, J and Brown, SDM and Fisher, EMC and Martin, JE A comprehensive ENU mutagenesis programme has produced novel neurological and behavioural phenotypes. In: (Proceedings) 29th Annual Meeting of the Society for Neurosciences Meeting.

Hunter, AJ and Hagan, JJ and Rogers, D and Nolan, P and Strivens, M and Peters, J and Brown, SDM and Martin, J and Fisher, EMC A comprehensive ENU mutagenesis programme has produced novel neurological and behavioural phenotypes. In: (Proceedings) 27th Meeting of the European Teratology Society.

Hunter, J and Rogers, D and Hagan, J and Peters, J and Nolan, P and Vizor, L and Thornton, C and Glenister, P and Greenaway, S and Hewitt, M and Selley, R and Strivens, M and Martin, J and Fisher, EMC and Rastan, S and Browne, M and Brown, S A comprehensive ENU mutagenesis programme for the mouse genome. In: (Proceedings) Physiological Society Meeting, Smithkline Beecham.

Isaacs, AM and Johannsen, P and Holm, I and Nielsen, JE and Fisher, E and Rossor, M and Gade, A and Thusgaard, T and Gydesen, S and Englund, E and Brown, J and Collinge, J (2011) Frontotemporal dementia caused by CHMP2B mutations. In: Current Alzheimer Research. (pp. 246 - 251).

Isaacs, AM and Skibinski, G and Parkinson, NJ and Brown, JM and Nielsen, JE and Thusgaard, T and Brun, A and Gade, A and Johannsen, P and Gydesen, S and Fisher, EMC and Collinge, J and FReJA-Consortium, A mutation in CHMP2B is the likely cause of frontotemporal dementia in a large Danish kindred. In: (Proceedings) Society for Neuroscience Meeting.

Isaacs, AM and Skibinski, G and Parkinson, NJ and Brown, JM and Nielsen, JE and Thusgaard, T and Brun, A and Gade, A and Johannsen, P and Gydesen, S and Fisher, EMC and Collinge, J and The-FReJA-Consortium, A mutation in the endosomal gene CHMP2B in frontotemporal dementia. In: (Proceedings) Society for Neuroscience.

Isaacs, AM and Skibinski, G and Parkinson, NJ and Brown, JM and Nielsen, JE and Thusgaard, T and Brun, A and Gade, A and Johannsen, P and Gydesen, S and Fisher, EMC and Collinge, J and The-FReJA-Consortium, Mutations in the endosomal gene CHMP2B in frontotemporal dementia. In: (Proceedings) 5th International Conference on Frontotemporal Dementia.

Isaacs, AM and Skibinski, G and Parkinson, NJ and Brown, JM and Nielsen, JE and Thusgaard, T and Brun, A and Gade, A and Johannsen, P and Gydesen, S and Fisher, EMC and Collinge, J and The-FReJA-Consortium, Mutations in the endosomal gene cHMP2B in frontotemporal dementia. In: (Proceedings) 5th International Conference on the frontotemporal dementias.

Johannsen, P and Eskildesen, S and Neilsen, J and Fisher, EMC and Zeidler, D and Rodell, A and Ostergaard, L (2006) Functional and structural imaging in FTD3. In: Alzheimer's & Dementia Journal. (pp. S15 - S15).

Johannsen, P and Eskildsen, SF and Nielsen, J and Fisher, EMC and Zeidler, D and Rodell, A and Ostergaard, L and The-FReJA-Consortium, (2006) Brain cortical thickness in a FTD3 patient and mutation carriers. In: The Alzheimer's Society Journal: Alzheimer's & Dementia. (pp. S15 - S15). Elsevier

Johannsen, P and Fraham-Falkenberg, S and Law, I and Jennum, P and Isaacs, A and Brown, J and Nielsen, JE and FreJA collaboration, Changes in cerebral glucose metabolism in early symptomatic frontotemporal dementia linked to chromosome 3 (FTD-3). In: (Proceedings) European Neurology Conference.

Johannsen, P and Frahm-Falkenberg, S and Law, I and Jennum, P and Isaacs, A and Brown, J and Nielsen, JE and FReJA Collaboration, (2011) CHANGES IN CEREBRAL GLUCOSE METABOLISM IN EARLY SYMPTOMATIC FRONTOTEMPORAL DEMENTIA LINKED TO CHROMOSOME 3 (FTD-3). In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 75 - 75). WILEY-BLACKWELL

Johannsen, P and Gade, A and Brown, J and Chakrabarti, L and Ghedde, A and Gydesen, S and Sorensen, SA and The-FReJA-Group, (2002) Extensive cerebral blood flow deficits in chromosome 3 frontotemporal dementia. In: Neurobiology of Ageing. (pp. S59 - S60).

Johannsen, P and Gade, A and Brown, J and Ghakrabarti, K and Gjedde, A and Gydesen, S and Sorensen, SA and PET-Centre-and-Dementia-Clinic, A-U-H-A-O-S Extensive cerebral blood flow deficits in chromosome 2 frontotemporal dementia. In: (Proceedings) 10th International Congress Psychogeriatric Association Meeting.

Johannsen, P and Gade, A and Brown, J and Gydesen, S and Chakrabarti, L and Thusgaard, T and Fisher, EMC and Rossor, M and Collinge, J and Gjedde, A and Sorensen, SA Chromosome-3 frontotemporal dementia (FTD3) with global cerebral blood flow decreases. In: (Proceedings) Annual Meeting Danish Neurological Society.

Johannsen, P and Holm, I and Eskildsen, SF and Rodell, A and Isaacs, AM and Gade, A and Nielsen, J and Ostergaard, L and Fisher, EMC and Collinge, J and Brown, J and The-FReJA-Consortium, New imaging and neuropathology findings in FRD-3 patients and mutation carriers. In: (Proceedings) 5th International Conference on Frontotemporal Dementia.

Johannsen, P and Roos, P and Law, I and Frahm-Falkenberg, S and Isaacs, A and Brown, J and Nielsen, JE (2012) Changes in Cerebral Glucose Metabolism in Early Symptomatic Frontotemporal Dementia Linked to Chromosome 3 (FTD-3). In: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. (pp. 130 - 131).

Johannsen, P and The-FReJA-Consortium, FTD3 brain imaging. In: (Proceedings) 4th International Conference on Frontotemporal Dementia.

Joyce, P and Fratta, P and Phatac, V and McGoldrick, P and Greensmith, L and Fisher, EMC and Acevedo-Arozena, A A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: (Proceedings) UK Neuromuscular Translational Research conference.

Joyce, P and Fratta, P and Phatac, V and McGoldrick, P and Greensmith, L and Fisher, EMC and Acevedo-Arozena, A A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: (Proceedings) UK Neuromuscular Translational Research conference.

Joyce, P and Fratta, P and Phatak, V and McGoldrick, P and Greensmith, L and Fisher, EMC and Acevedo-Arozena, A A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: (Proceedings) American Society of Neuroscience Annual meeting.

Joyce, P and Fratta, P and Phatak, V and McGoldrick, R and Greensmith, L and Fisher, EMC and Acevedo-Arozena, A (2011) A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: NEUROMUSCULAR DISORDERS. (pp. S6 - S6). PERGAMON-ELSEVIER SCIENCE LTD

Katsanis, N and Fisher, EMC Adding to the transcription map of HSA21. In: (Proceedings) 7th International Chromosome 21 Workshop.

Katsanis, N and Fisher, EMC Identification and mapping single copy expressed sequences on human chromosome 21. In: (Proceedings) 6th International Workshop on Human Chromosome 21.

Katsanis, N and Humphreys, C and Sarner, S and de-Belleroche, J and Collinge, J and Fisher, EMC An improved protocol for the analysis of Sod1 gene mutations: screening of UK ALS families. In: (Proceedings) 5th International Symposium on ALS and other MND.

Katsanis, N and Yaspo, ML and Fisher, EMC (1995) cDNA selection from human chromosome 21. In: Genetics Research (Camb).

Katsanis, N and Yaspo, ML and Fisher, EMC Enrichment of the expressed sequence map of human chromosome 21. In: European Journal of Human Genetics.

Katsanis, N and Yulug, I and Yaspo, ML and Fisher, EMC Analysis of expressed sequences from human chromosome 21. In: (Proceedings) Gordon Research Conference on Human Molecular Genetics.

Katsanis, N and Yulug, IG and Yaspo, ML and Hernandez, D and Fisher, EMC cDNA selection and isolation from human chromosome 21. In: (Proceedings) 5th International Workshop on Human Chromosome 21.

Kieran, D and Hafezparast, M and Bohnert, S and Dick, J and Martin, J and Schiavo, G and Fisher, EMC and Greensmith, L A mutation in dynein rescules defects in retrograde axonal transport and delays disease progression in SOD1G93A mice. In: (Proceedings) Society for Neuroscience Annual Meeting.

Kieran, D and Hafezparast, M and Bohnert, S and Dick, J and Martin, J and Schiavo, G and Fisher, EMC and Greensmith, L Disrupted axonal transport in SOD1G93A transgenics is restored by mutant dynein, so significantly extending lifespan. In: (Proceedings) 15th International ALS symposium.

Kieran, D and Hafezparast, M and Bohnert, S and Dick, JRT and Martin, J and Schiavo, G and Fisher, EMC and Greensmith, L A point mutation in dynein delays disease progression in SOD1G93A mice, a model of amyotrophic lateral sclerosis. In: (Proceedings) 5th Jackson Lab Neurogenetics Conference.

Kieran, D and Hafezparast, M and Martin, JE and Fisher, EMC and Greensmith, L (2003) Delaying disease progression in mSOD transgenic mice. In: Amyotroph. Lateral Scler Other Motor Neuron Disord. (pp. 5 - 227).

Knapp, S and Hosie, AM and Anstee, QM and Thomos, P and Mortensen, M and Martinez, A and Tymowska-Lalanne, Z and McQuillin, A and Gurling, HM and Morgan, MY and Kuo, YT and Herlihy, A and Bell, JD and Robinson, I and Fisher, E and Brown, S and Stephens, D and Smart, TG and Thomas, HC (2008) IDENTIFICATION OF A MODEL OF ALCOHOL PREFERENCE AND ITS SIMILARITY TO HUMAN ALCOHOLISM. In: HEPATOLOGY. (pp. 398A - 399A). JOHN WILEY & SONS INC

Knapp, S and Hosie, AM and Thomas, P and Martinez, A and Mortensen, M and Brown, SDM and Fisher, EMC and Smart, TG and Thomas, HC Mutation of the GABA a receptor b1 gene with ENU results in alcohol preference in mice. In: (Proceedings) European Society for Biomedical Research in Alcoholism.

Kuta, A and Banks, G and Parkinson, N and Quwailid, MM and Fisher, EMC Screening for dynein complex mutations in an ENU mouse library. In: (Proceedings) International Mammalian Genome Conference.

Lana-Elola, E and Watson-Scales, S and Slender, A and Dunlevy, L and Bennett, M and Mohun, T and Fisher, EMC and Tybulewicz, V Engineering new mouse models to map dosage-sensitive genes in Down syndrome congenital heart defects. In: (Proceedings) Weinstein Cardiovascular Conference.

Levey, PM and Bermingham, NA and Fisher, EMC and Martin, JE Expression of lysosomal membrane glycoproteins LAMP-1 and LAMP-2 in the central nervous system. In: (Proceedings) Neuropathological Society.

Levey, PM and Bermingham, NA and Fisher, EMC and Martin, JE Expression of lysosomal membrane glycoproteins LAMP-1 and LAMP-2 in the central nervouse system. In: Neuropathology and Applied Neurobiology.

Line, SJ and Papaioannou, D and Fisher, EMC and Tybulewicz, VJL and Bannerman, DM and Deacon, R An aneuploid mouse which models Down syndrome displays deficits in spatial working memory and motor coordination. In: (Proceedings) Firt AnEUploidy Workshop.

Lloyd, S and Onwuazor, O and Uphill, J and Beck, J and Farrall, M and Targonski, P and Collinge, J and Fisher, EMC Identification of multiple quantitative trait loci linked to prion disease incubation time. In: (Proceedings) 15th International Mouse Genome Conference.

Lloyd, SE and Beck, JA and Fisher, EMC and Collinge, J Quantative trait locus analysis of prion disease incubation time. In: (Proceedings) 13th International Mouse Genome Conference.

Lloyd, SE and Maytham, ELG and Thompson, S and Mott, R and Fisher, EMC and Collinge, J Fine mapping prion disease incubation time QTL using heterogeneous stock mice. In: (Proceedings) 18th International Mouse Genome Conference.

Lloyd, SE and Thompson, S and Mott, R and Collinge, J and Fisher, EMC Quantitative trait locus analysis of prion disease incubation time in mice. In: (Proceedings) 19th International Congress of Genetics.

Lloyd, SE and Thompson, S and Mott, R and Fisher, EMC and Collinge, J Quantitative trait locus analysis of prion disease incubation time in mice. In: (Proceedings) Complex Trait Consortium meeting.

Lunau, I and Mouridsen, K and Rodell, A and Nielsen, J and Isaacs, A and Brown, J and Zeidler, D and Ostergaard, L and Eskildsen, SF and Johannsen, P and The-FReJA-Consortium, Changes in cerebral blood flow in presymptomatic mutation carriers of familial frontotemporal dementia (FTD-3), measured with MRI. In: (Proceedings) 10th Alzheimer's Association International Conference.

Martin, J and Bermingham, N and Mileham, P and Peters, J and Fisher, EMC A model of neurological disease with anterior horn cell degeneration - legs at odd angles. In: Journal of Neuroscience.

Martin, JE and Fisher, EMC and Mackin, J and Ball, ST and Nicholson, SJ and Witherden, AS and Hafezparast, M and ten-Ashbroek, A and Peters, J and Baas, F Genetic localisation of the Legs at odd angles locus and analysis of the human syntenic region. In: (Proceedings) ALS and other Motor Neurone Diseases Association Meeting.

Martin, JE and Fisher, EMC and Peters, J and Hunter, J and Brown, SDM and Rogers, D (1997) SHIRPA - Phenotypic assessment of neurological function. In: Neuropathaolgy and Applied Neurobiology.

Martin, JE and Hafezparast, M and Rurhberg, C and Ahmad-Annuar, A and Bowen, S and Ball, S and Morrison, K and Shaw, P and Schiavo, G and Shima, DT and Peters, J and Fisher, EMC Genetic characterisation of the Legs at odd angles locus, a new mutation causing motor neuron degeneration in a gene dose dependent manner. In: (Proceedings) 13th International Symposium on ALS/MND.

Martin, JE and Nicholson, SJ and Hafezparast, M and Witherden, A and Cooper, E and Baker, CS and Fisher, EMC Mass spectrometry: a tool to screen mice for inborn errors of metabolism. In: (Proceedings) XiVth Congress of Neuropathology.

Martin, JE and Peters, J and Mileham, P and Brown, SDM and Hunter, AJ and Fisher, EMC Use of a standardised screening protocol for the assessment of phenotype in mouse models of motor neuron disease. In: Journal of Neuroscience.

Martin, JE and Rogers, D and Hunter, AJ and Peters, J and Brown, SDM and Fisher, EMC SHIRPA - A standardised protocol for phenotypic assessment. In: (Proceedings) 10th International Mouse Genome Conference.

Martin, JE and Sadri, R and Naase, M and Vizor, L and Nolan, P and Fisher, EMC Mouse models of motor neuron dysfunction arising from a large scale mutagenesis programme. In: (Proceedings) 11th International Symposium on ALS and other MNDs.

Martinez, A and Jones, L and Rosankiewicz, J and Brown, SDM and Thomas, H and Fisher, EMC (2002) Mapping, isolation and charactrization of gene(s) involved in ethanol preferences: Pilot study. In: Genetics Research. : Cambridge Journals online.

McGoldrick, P and Dick, J and Ricketts, T and Acevedo-Arozena, A and Fisher, E and Greensmith, L (2010) Investigating novel mutant mouse models of motor neuron disease. In: NEUROMUSCULAR DISORDERS. (pp. S13 - S13). PERGAMON-ELSEVIER SCIENCE LTD

McGoldrick, P and Dick, J and Ricketts, T and Acevedo-Arozena, A and Fisher, EMC and Greensmith, L Investigating novel mutant mouse models of motor neuron disease. In: (Proceedings) UK Neuromuscular translational research conference.

McGoldrick, P and Dick, J and Ricketts, T and Joyce, P and Fratta, P and Acevedo-Arozena, A and Fisher, EMC and Greensmith, L (2011) Investigating novel mutant mouse models of motor neuron disease. In: NEUROMUSCULAR DISORDERS. (pp. S11 - S11). PERGAMON-ELSEVIER SCIENCE LTD

McGoldrick, P and Joyce, P and Acevedo, A and Fisher, EMC and Greensmith, L Investigating New Mutant Models of Amyotrophic Lateral Sclerosis. In: (Proceedings) American Society of Neuroscience Annual meeting.

McGoldrick, P and Joyce, P and Acevedo-Arozena, A and Fisher, E and Greensmith, L (2012) Investigating new mutant models of MND. In: NEUROMUSCULAR DISORDERS. (pp. S13 - S13).

McGoldrick, P and Joyce, P and Saccon, R and Acevedo-Arozena, A and Fisher, EMC and Greensmith, L (2013) An ENU-induced point mutation in mouse Sod1 causes aberrant mitochondrial function and axonal maintenance in primary motor neurons. In: (Proceedings) Annual Meeting, MRC Centre for Neuromuscular Disease.

Mead, SH and Mahal, SP and Farrall, M and Fisher, EMC and Collinge, J Association of prion protein gene single nucleotide polymorphism haplotypes with Creutzfeldt-Jakob disease. In: (Proceedings) American Society of Human Genetics.

Mensah, A and Linehan, J and Ruf, S and O'Doherty, A and Burtscher, I and Mulligan, C and Tybulewicz, VLJ and Fisher, EMC and Brandner, S and Nizetic, D Embryonic stem cell derived transchromosomal teratocarcinoams: an attempt to map human chromosome 21 gene-dose effects on tumour suppression and neuronal differentiation. In: (Proceedings) William Harvey Day, Barts and the London School of Medicine and Dentistry.

Mensah, A and Mulligan, C and Linehan, J and Ruf, S and O'Doherty, A and Hernandez, D and Grygalewicz, B and Shipley, J and Groet, J and Tybulewicz, VLJ and Fisher, EMC and Brandner, S and Nizetic, D Suppression of neural fate of pluripotent mouse embryonic stem cells in vivo by trisomy 21, using a novel experimental system of transchromosomic teratomas. In: (Proceedings) 3rd International Conference on Chromosome 21 and medical reserch on Down Syndrome.

Mileham, P and Fisher, EMC and Neal, L and Peters, J and Martin, JE (1997) Genetic mapping of the gammy (gam) mutation - a putative model of human congenital club foot. In: Neuropathology and Applied Neuropathology.

Mileham, P and Peters, J and Martin, J and Fisher, EMC Investigations into the gammy (gam) mutation - a putative mouse model for human focal dystonic syndromes. In: (Proceedings) Second Mouse Molecular Neurogenetics Meeting.

Morice, E and Cooke, SF and Vanes, L and Fisher, EMC and Tybulewicz, VLJ and Bliss, TVP Motor dysfunction and impairments in short-term memory and synaptic plasticity in a mouse model (Tc1) of Down syndrome. In: (Proceedings) British Neuroscience Meeting.

Morsi, A and Soura, V and Chia, R and Jackson, G and Greensmith, L and Fisher, EMC and Hafezparast, M Analysis of the role of dynein mutations in attenuating the phenotype of mutant-SOD1 transgenic mice. In: (Proceedings) 17th ALS/MND Symposium.

Morsi, A and Stoddart, E and Bros, C and Fisher, EMC and Greensmith, L and Hafezparast, M Analysis of the role of cytoplasmic dynein in the toxicity of SOD1G93A. In: (Proceedings) 18th ALS/MND Symposium.

Morsi-El-Kadi, A and Schiavo, G and Ahman-Annuar, A and Martin, J and Fisher, EMC and Hafezparast, M Defective retrograde axonal transport and motor neuron degeneration. In: (Proceedings) The British Society for Cell Biology Annual Meeting.

Morsi-El-Kadi, A and Soura, V and Bohnert, S and Lo, K and Pfister, K and Wheatley, S and Martin, J and Ahmad-Annuar, A and Fisher, EMC and Greensmith, L and Schiavo, G and Hafezparast, M (2005) Molecular analysis of motor neuron degeneration caused by mutant dynein. In: ALS and Other MNDs.

Mulligan, C and Mensah, A and Burtscher, I and Groet, J and Schnappauf, F and Ruf, S and O'Doherty, A and Hernandez, D and Shipley, J and Denyer, G and Epstein, CJ and Tybulewicz, VLJ and Fisher, EMC and Nizetic, D Trisomy 21-caused deregulation of non-HSA21 genes persists from undifferentiated ES cell to adulthood, in mouse models of Down syndrome. In: (Proceedings) 3rd International Conference on Chromosome 21 and Medical Research on Down Syndrome.

Mulligan, C and Ruf, S and O'Doherty, A and McElwaine, S and Cotter, FE and Mensah, A and Burtscher, I and Groet, J and Tybulewicz, VLJ and Fisher, EMC and Nizetic, D An embryonic stem cell approach to identify genes for lineage decisions in differentiating neruonal and haematopoetic cells in Down syndrome. In: (Proceedings) William Harvey Day, Barts and the London School of Medicine and Dentistry.

Murdoch, J and Quint, E and Curtin, J and Henderson, D and Greene, N and Arkell, R and Bogani, D and Gerrelli, D and Doudney, K and Paternotte, C and Cattanach, B and Nolan, P and Spurr, N and Fisher, E and Stanier, P and Gray, I and Steel, K and Brown, S and Copp, A (2004) Mechanisms regulating the initiation of neural tube closure. In: GENETICAL RESEARCH. (pp. 121 - 121). CAMBRIDGE UNIV PRESS

Nasir, J and Fisher, EMC and Brockdorff, N and Disteche, CM and Lyon, MF and Brown, SDM (1990) Unusual molecular characteristics of a repeat sequence island within a Giemsa positive bankd on the mouse X chromosome. In: Genetics Research. (pp. 126 - ?).

Nicholson, S and Witherden, A and Hafezparast, M and Bermingham, NA and Ball, ST and Peters, J and Martin, JE and Fisher, EMC Isolating the gene for Loa, a mouse model of dominant motor neuron degeneration. In: (Proceedings) Genetical Society Meeting.

Nicholson, S and Witherden, A and Peters, J and Ball, S and Martin, J and Rogers, D and EMC, F and Hafezparast, M Mapping of a mouse motor neuron disease gene, Loa. In: (Proceedings) Symposium on Molecular Medicine, Imperial College.

Nicholson, S and Witherden, A and Peters, J and Ball, S and Martin, JE and Rogers, D and Fisher, EMC and Hafezparast, M Mapping of a motor neuron disease gene, Loa, to the distal region of Mmu12. In: (Proceedings) Mouse Genome meeting.

Nicholson, SJ and Bermingham, NA and Ball, ST and Peters, J and Martin, JE and Fisher, EMC Isolating the gene for Loa, a mouse model of dominant motor neuron degeneration. In: (Proceedings) 11th International Mouse Genome Conference.

Nicholson, SJ and Witherden, AS and Hafezparast, M and Peters, J and Martin, JE and Rogers, JC and Fisher, EMC Mapping of Loa, a mouse motor deficit gene. In: (Proceedings) Association of Physicians meeting.

Nickols, C and Mileham, P and Peters, J and Fisher, EMC and Martin, JE Gammy - the mouse that limps. In: (Proceedings) 10th International Mouse Genome Conference.

Nickols, CD and Fisher, EMC and Martin, JE Study of the development of the hindlimb in the gammy (gam) mouse. In: (Proceedings) British Neuropathological Society.

Nickols, CD and Peters, J and Fisher, EMC and Martin, JE (1998) Muscle and nerve morphology in the affected hindlimb of the mouse mutant 'gammy' (gam) a model of human club foot. In: Brain pathology.

Nickols, CD and Peters, J and Fisher, EMC and Martin, JE (1997) A closer look at the mouse mutant 'gammy' (gam), a proposed model for human club foot. In: Neuropathology and Applied Neuropathology.

Nickols, CD and Peters, J and Fisher, EMC and Martin, JE Morphology of the nerve supply to the lower limb in the gammy (gam) mouse. In: (Proceedings) British Neuropathological Society Meeting.

Nickols, CD and Peters, J and Saleem, S and Fisher, EMC and Martin, JE Gammy - the mouse that limps. In: (Proceedings) 93rd Meeting of the British Neuropathological Society.

Nickols, CK and Peters, J and Fisher, EMC and Martin, JE (1997) Phenotypic analysis of the mouse mutant gammy (gam) and the effects of laterality on scoring in the SHIRPA protocol. In: Beuropathology and Applied Neuropathology.

Nickols, CK and Peters, J and Fisher, EMC and Rogers, D and Martin, JE Phenotypic analysis of the mouse mutant gammy (gam) and the effects of laterality on scoring in the SHIRPA protocol. In: (Proceedings) British Neuropathological Society Meeting.

Nolan, P and Peters, J and Vizor, L and Washbourne, R and Thornton, C and Glenister, P and Greenaway, S and Hewitt, M and Selley, R and Strivens, M and Martin, J and Fisher, EMC and Rogers, D and Hagan, J and Spurr, N and Rastan, S and Browne, M and Hunter, J and Brown, S Systematic approaches to identifying novel behavioural mutations using ENU mutagenesis. In: (Proceedings) 13th International Mouse Genome Conference.

Nolan, PM and Peters, J and Vizor, L and Strivens, M and Washbourne, R and Hough, T and Glenister, PI and Thornton, C and Greenaway, S and Hewitt, M and Liu, X and McCormack, S and Selley, R and Wells, C and Tymowska-Lalanne, Z and Roby, P and Martin, J and Fisher, EMC and Rogers, D and Hagan, J and Reavill, C and Gray, I and Wood, J and Spurr, N and Browne, M and Rastan, S and Hunter, J and Brown, SDM Genetic and functional studies of mutations identified in a large scale ENU mutagenesis screen. In: (Proceedings) 14th International Mouse Genome Conference.

Nolan, PM and Peters, J and Vizor, L and Strivens, M and Washbourne, R and Hough, T and Wells, C and Glenister, P and Thornton, C and Martin, J and Fisher, EMC and Rogers, D and Hagan, J and Reavill, C and Gray, I and Wood, J and Spurr, N and Browne, M and Rastan, S and Hunter, J and Brown, SDM The generation of a new mutant map of the mouse. In: (Proceedings) 13th Annual CSH meeting on Genome Sequencing and Biology meeting.

Norris, FC and Cleary, JO and Modat, M and Sinclair, B and Mccue, K and Wells, JA and Martinez-Barbera, JP and Brander, S and Fisher, E and Scambler, PJ and Ourselin, S and Lythgoe, MF (2011) Mouse phenotyping using high resolution 3D microscopic magnetic resonance imaging. In: GENETICS RESEARCH. (pp. 440 - 440).

Norris, FC and Cleary, JO and Modat, M and Sinclair, B and McCue, K and Wells, JA and Martinez-Barbera, JP and Brandner, S and FISHER, E and Scambler, PJ and Oourselin, S and Lythgoe, MF Mouse phenotyping using high resolution 3D microscopic magnetic resonance imaging. In: (Proceedings) Mammalian Genetics and Development Workshop, UCL.

Norris, FC and Cleary, JO and Modat, M and Sinclair, B and McCue, K and Wells, JA and Martinez-Barbera, JP and Brandner, S and Fisher, EMC and Scambler, PJ and Lythgoe, MF Mouse phtnotyping using high resolution 3D microscopic magenetic resonance imaging. In: (Proceedings) Mammalian Genetics and Development Workshop.

O'Doherty, A and Ruf, S and Hernandez, D and Tybulewicz, V and Fisher, EMC (2001) Generation of transchromosomal mice using ES cells containing freely segregating fragments of human chromosome 21 (Hsa21): a model of human Down syndrome. In: Copp, AJ and Fisher, EMC, (eds.) Genetics Research. (pp. 200 - ?). Cambridge Journals

O'Doherty, A and Ruf, S and Hernandez, D and Tybulewicz, V and Fisher, EMC (2001) Generation of transchromosomal mice using ES cells containing freely segregating fragments of Hsa21: a model for human Down syndrome. In: Cytogenetics and Cell Genetics.

O'Doherty, A and Ruf, S and Hernandez, D and Tybulewicz, V and Fisher, EMC Creation of transchromosomal mice for the study of Down syndrome: issues related to germline transmission of Hsa21 in mouse ES cells. In: (Proceedings) Mouse Molecular Genetics Meeting.

O'Doherty, A and Ruf, S and Mulligan, C and Cooke, S and Vanes, L and Hernandez, D and Sharpe, PT and Brandner, S and Bliss, TVP and Henderson, DJ and Nizetic, D and Tybulwicz, VLJ and Fisher, EMC An aneuploid mouse with a human chromosome modelling Down syndrome. In: (Proceedings) British Neuroscience Meeting.

O'Doherty, A and Ruf, S and Mulligan, C and Hildreth, V and Errington, ML and Cooke, S and Sesay, A and Modino, S and Vanes, L and Hernandez, D and Linehan, JM and Sharpe, P and Brandner, S and Bliss, TVP and Henderson, DJ and Nizetic, D and Tybulewicz, VLJ and Fisher, EMC The Tc1 mouse an aneuploid mouse with a human chromosome that modesl aspects of Down syndrome. In: (Proceedings) European Society for Human Genetics.

O'Doherty, A and Ruf, S and Tybulewicz, VLJ and Fisher, EMC Germline transmission of Hsa21 in the mouse: a model of human Down syndrome. In: (Proceedings) 10th International Meeting Molecular Biology of Chromosome 21 and Down syndrome.

O'Donnell, H and Johnston, K and McKie, J and Strutt, P and Yulug, I and Scambler, P and Fisher, EMC Cloning genes from chromosome 21. In: (Proceedings) Gordon Research Conference on Molecular Genetics.

Page, DC and Fisher, EMC and Beer-Romero, P and Ridley, A and Brown, LG Homologous ribosomal protein genes on the human X and Y chromosomes may underlay the aploinsufficiency in Turner syndrome. In: American Journal of Human Genetics.

Page, DC and Fisher, EMC and Beer-Romero, P and Ridley, A and Brown, LG Isolating genes from the human X and Y chromosome. In: (Proceedings) Gordon Research Conference on Mammalian Gametogenesis and Embryogenesis.

Peters, J and Vizor, L and Thornton, C and Glenister, P and Middlehurst, P and Selley, R and Strivens, M and Brown, S and Martin, J and Fisher, EMC and Rogers, D and Hagan, J and Rastan, S and Browne, M and Hunter, J A comprehensive ENU mutagenesis programme for the mouse genome. In: (Proceedings) 11th International Mouse Genome Conference.

Philpott, A and Bros, V and Flenniken, A and Schiavo, G and Fisher, E and Greensmith, L and Hafezparast, M (2009) Cellular and molecular characterization of abnormal rear leg (Arl) - a new mouse strain with a point mutation in cytoplasmic dynein. In: GENETICS RESEARCH. (pp. 133 - 134). CAMBRIDGE UNIV PRESS

Price, KM and Hussain, I and Mustafa, A and Nickols, CD and Bird, MM and Ateh, D and Baker, CS and Greensmith, L and Schiavo, G and Hafezparast, M and Fisher, EMC and Martin, JE Subcellular functional specificyt of dynein-dynactin complex subunits - disturbances in neurodegenerative disease. In: ALS and Other MNDs.

Reynolds, L and Baker, M and Fisher, EMC and Tybulewicz, VLJ and Hodivala-Dilke, K Trisomy of chromosome 21 inhibits angiogenesis. In: (Proceedings) Keystone conference on Angiogenesis and Lymphanogiogenesis in Cancer.

Richardson, S and Menendez, G and Siow, B and Wells, J and Fisher, EMC and Schiavo, G and Lythgoe, MF MRI detection of axonal transport via tetanus neurotoxin bound iron oxide nanoparticles. In: (Proceedings) International Society for Magnetic Resonance in Medicine - 16th annual meeting.

Richtsmeier, J and Hill, C and Wilmore, K and Fisher, EMC and Tybulewicz, VLJ and Sharpe, P and Reeves, R Skull shape in Down syndrome mouse models. In: (Proceedings) Expert workshop on biology of chromosome 21 genes: Towards gene-phenotype correlations in Down Syndrome.

Ricketts, T and Fisher, EMC and Acevedo-Arozena, A Tdp43: searching for new mouse models of ALS. In: (Proceedings) MRC Mammalian Genetics Unit, Site visit.

Ricketts, T and Fratta, P and Joyce, P and McGoldrick, P and Kent, R and Greensmith, L and Acevedo-Arozena, A and Fisher, E Functional characterization of mouse TDP-43 point mutations generated by chemical mutagenesis. In: (Proceedings) Society for Neuroscience Meeting.

Ricketts, T and Fratta, P and Joyce, P and McGoldrick, P and Kent, R and Greensmith, L and Acevedo-Arozena, A and Fisher, EMC Functional characterization of mouse TDP-43 point mutations generated by chemical mutagenesis. In: (Proceedings) American Society of Neuroscience Annual meeting.

Ricketts, T and Fratta, P and Joyce, P and McGoldrick, P and Kent, R and Greensmith, L and Acevedo-Arozena, A and Fisher, EMC Functional characterization of mouse TDP-43 point mutations generated by chemical mutagenesis. In: (Proceedings) American Society of Neuroscience Annual meeting.

Ricketts, T and Fratta, P and Joyce, P and McGoldrick, P and Kent, R and Line, S and Greensmith, L and Acevedo-Arozena, A and Fisher, EMC Chatacterisation of mouse TDP43 point mutations generated by chemical mutagenesis. In: (Proceedings) American Society of Neuroscience Annual meeting.

Robson, JC and Sangha, HK and Gupta, S and Bird, MM and Bowen, S and Ball, S and Fisher, EMC and Nickols, C and Peters, J and Thavapalasundaru, J and Martin, JE Gammy, a spectrum of skull defects. In: (Proceedings) William Harvey Day, Queen Mary and Westfield College.

Rogers, DC and Hunter, AJ and Hockings, PD and Martin, JE and Peters, J and Cattanach, BM and Fisher, EMC Development of the 'SHIRPA' procedure to characterise the phenotype of mouse mutation. In: (Proceedings) Second Mouse Molecular Neurogenetics Meeting.

Ruparelia, A and Pearn, M and Wu, C and Schiavo, G and Fisher, EMC and Tybulewicz, V and Mobley, W The effect of trisomic Hsa21 genes on axonal transport and neuronal morphology in a mouse model of Down syndrome. In: (Proceedings) American Society of Neuroscience Annual meeting.

Ruparelia, A and Wiseman, F and Sheppard, O and Kuta, A and Slender, A and Tybulewicz, VLJ and FISHER, E Endocytic trafficking in a panel of mice that model Down syndrome. In: (Proceedings) Biochemical Society meeting - Models of dementia: the good, the bad and the future.

Ruparelia, A and Wiseman, F and Sheppard, O and Kuta, A and Slender, A and Tybulewicz, VLJ and Schiavo, G and Fisher, EMC Endocytic trafficking in a panel of mice that model Down syndrome. Models of dementia: the good the bad and the future. In: (Proceedings) Biochemical Society meeting.

Ruparelia, A and Wiseman, F and Sheppard, O and Kuta, A and Tybulewicz, VLJ and Schiavo, G and Fisher, EMC Endocytic trafficking in a panel of mice that model Down syndrome. In: (Proceedings) 2nd Aneuploidy Workshop.

Saccon, R and Joyce, P and Fratta, P and Greensmith, L and Acevedo, A and Fisher, EMC (2012) Characterisation of a unique SOD1 mouse model for ALS. In: (Proceedings) UCL Institute of Neurology Student Symposium.

Saccon, R and Joyce, P and Fratta, P and Greensmith, L and Acevedo, A and Fisher, EMC Characterisation of a unique SOD1 mouse model for ALS. In: (Proceedings) American Society of Neuroscience Annual meeting.

Sadri, R and Fisher, EMC and Martin, J New animal models of motor neurone disease. In: (Proceedings) British Neuropathology Society.

Sadri, R and Fisher, EMC and Martin, JE Phenotypes analysis of potential mouse models of motor neuron disease: a protocol. In: (Proceedings) British Neuroscience Association.

Sangha, HK and Robson, JC and Bowen, S and Nadarajan, V and Ball, S and Fisher, EM and Nickols, C and Peters, J and Martin, JE (2003) Deletion studies in the gammy mouse. In: JOURNAL OF PATHOLOGY. (pp. 55A - 55A). JOHN WILEY & SONS LTD

Schmitt, K and Vollrath, D and Foote, S and Fisher, EMC and Goradia, T and Page, D and Arnheim, N Linkage analysis of human pseudoautosomal polymorphisms using single sperm typing: do double crossovers occur during male meiosis. In: Am. J. Hum. Genet.

Shah, PR and Ahmad-Annuar, A and Ahmadi, KR and Soranzo, N and Russ, C and Sapp, PC and Kasperaviciute, D and Horvitz, HR and Brown, RH and Goldstein, DB and Fisher, EMC (2005) Towards a systematic screen of cytoplasmic dynein-dynactin genes and other candidates for association with motor neuron degeneration disorders by tagging SNP analysis. In: ALS and Other MNDs.

Shah, PR and Ahmad-Annuar, A and Ahmadi, KR and Soranzo, N and Russ, C and Sapp, PC and Kasperaviciute, D and Horvitz, HR and Brown, RH and Goldstien, DB and Fisher, EMC Towards a systematic screen of cytoplasmic dynein-dynactin genes and other candidates for association with motor neuron degeneration disorders by tagging SNP analysis. In: (Proceedings) American Society of Human Genetics meeting.

Shah, PR and Mead, S and Poulter, M and Campbell, T and Uphill, J and Adamson, G and Beck, J and Whitfield, J and Alpers, M and Fisher, EMC and Collinge, J A Search for acquired prion disease susceptibility loci: genetic investigations in kuru. In: (Proceedings) Institute of Neurology.

Sheppard, O and Plattner, F and Rubin, A and Tybulewicz, VLJ and Fisher, EMC and Wiseman, FK Trisomy of DYRK1A and phosporylation of Tau in a mouse model of Down syndrome. In: (Proceedings) 2nd Aneuploidy workshop.

Sinclair, B and Cleary, JO and Modat, M and Norris, VC and Wiseman, F and Tybulewicz, V and FISHER, E and Lythgoe, MF and Ourselin, S Tensor-based morphometry of the Tc1 mouse model of Down syndrome highlights previously undetected phenotypes. In: (Proceedings) International Society for Magnetic Resonance in Medicine 2011.

Sinclair, B and Cleary, JO and Modat, M and Norris, VC and Wiseman, F and Tybulewicz, V and Fisher, EMC and Lythgoe, MF and Ourselin, S Tensor-based morphometry of the Tc1 mouse model of Down syndrome highlights previously undetected phenotypes. In: (Proceedings) International Society for Magenitc Resonance in Medicine.

Sinclair, B and Cleary, JO and Modat, M and Norris, VC and Wiseman, F and Tybulewicz, V and Fisher, EMC and Lythgoe, MF and Ourselin, S Tensor-based morphometry of the Tc1 mouse model of Down syndrome highlights previously undetected phenotypes. In: (Proceedings) International Society for Magenitc Resonance in Medicine.

Sinclair, B and Modat, M and Cleary, JO and Norris, FC and Wiseman, F and Fisher, EMC and Lythgoe, MF and Ourselin, S Automated tensor based morphometry for phenotyping the Tc1 mouse model of Down syndrome. In: (Proceedings) 16th Annual Meeting of the International Society for Magnetic Resonance in Medicine.

Skibinski, G and Chakrabarti, L and Fisher, EMC and Collinge, JC and FReJA-Consortium, The molecular characterisation of Frontotemporal dementia linked to Human Chromosome 3 (FTD-3). In: (Proceedings) Postgraduate student day, Institute of Neurology.

Skibinski, G and Chakrabarti, L and FReJA, (2003) Clinical and molecular characterization of frontotemporal dementia linked to human chromosome 3. In: GENETICAL RESEARCH. (pp. 231 - 231).

Skibinski, G and Chakrabarti, L and FReJA, (2002) Clinical and molecular characterisation of Frontotemporal dementia linked to Human Chromosome 3. In: AMERICAN JOURNAL OF HUMAN GENETICS. (pp. 539 - 539).

Skibinski, G and Chakrabarti, L and FReJA, Clinical and molecular characterisation of frontotemporal dementia linked to human chromosome 3. In: (Proceedings) American Society of Human Genetics.

Skibinski, G and Chakrabarti, L and The-FReJA-Consortium, The molecular characterisation of Frontotemporal dementia linked to Human Chromosome 3 (FTD-3). In: (Proceedings) 4th International Conference on Frontotemporal Dementia.

Skibinski, G and Parkinson, N and Fisher, E and Collinge, J and Freja Consortium, (2006) Mutations in the endosomal ESCRTIII complex subunit CHMP2B in frontotemporal dementia. In: GENETICAL RESEARCH. (pp. 75 - 76). CAMBRIDGE UNIV PRESS

Soura, V and Morsi-Ed-Kadi, A and Kuta, A and Deng, W and Stoddart, E and Fisher, EMC and Schiavo, G and Hafezparast, M A point mutation in cytoplasmic dynein impairs receptor tyrosine kinase (RTK) endocytic transport in the Legs at odd angles (Loa) mouse model. In: (Proceedings) Biochemical Society meeting "The Dynamic Cell" 2009.

Stephens, J and Greensmith, L and Martin, JE and Schiavo, G and Fisher, EMC Dissecting the mechanisms of motor neuron disease. In: (Proceedings) Institute of Neurology, Queen Square Symposium.

Stephens, J and Greensmith, L and Martin, JE and Schiavo, G and Fisher, EMC Dissecting the molecular mechanisms of motor neuron disease. In: (Proceedings) EMBO/FEBS Workshop on Systems Dynamics of Intracellular Communication.

Stevens, J and Hendriks, W and Bros-Facer, V and Greensmith, L and Martin, J and Schiavo, G and Fisher, EMC An investigation of SOD1 behaviour in amyotrophic lateral sclerosis. In: (Proceedings) Association of British Neurologists.

Stevens, J and Hendriks, W and Bros-Facer, V and Greensmith, L and Martin, J and Schiavo, G and Fisher, EMC An investigation of SOD1 behaviour in amyotrophic lateral sclerosis. In: (Proceedings) American Academy of Neurology.

Stevens, JC and Bros-Facer, V and Hendriks, W and van Minnen, J and Greensmith, L and Martin, JE and Fisher, EMC (2009) HOW DOES A DYNEIN MUTATION SLOW MOTOR NEURONE DISEASE? In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. ? - ?). B M J PUBLISHING GROUP

Stevens, JC and Hendricks, W and Martin, JE and Greensmith, L and Schiavo, G and Fisher, EMC How does a dynein mutation slow motor neuron disease. In: (Proceedings) Inaugural meeting, MRC Centre for Neuromuscular Disease.

Tsipouri, V and Curtin, JA and Hough, T and Nolan, PM and Rooke, LJ and Vizor, L and Hunter, AJ and Rogers, D and Rastan, S and Martin, J and Brown, SDM and Fisher, EMC and Spurr, NK and Gray, IC Mapping an ENU mutagenesis derived, lov total cholesterol, low HDL-cholesterol mutant mouse to chromosome 4. In: (Proceedings) Human Molecular Genetics Gordon Conference.

Tsipouri, VD and Curtin, JA and Nolan, PM and Rooke, LJ and Vizor, L and Martin, JE and Peters, J and Hunter, AJ and Rogers, D and Rastan, S and Brown, SDM and Fisher, EMC and Spurr, NG and Gray, IC Three novel pigmentation mutants generated by mouse ENU mutagenesis. In: (Proceedings) HUGO Human Genome Meeting.

Tybulewicz, V and Fisher, EMC Mouse models of Down Syndrome: why make them and what can we learn from them? In: (Proceedings) Down Syndrome Association AGM.

Tybulewicz, VLJ and Morice, E and Dunlevy, L and Alford, K and Lana-Elola, E and Watson, S and Wiseman, F and Fiegler, H and Rajan, D and Vanes, L and Tadrzak, A and Broughton, T and Carter, N and Mohun, T and Bliss, TVP The Tc1 mouse model of Down syndrome. In: (Proceedings) First AnEUploidy Workshop.

Tybulewicz, VLJ and O'Doherty, A and Ruf, S and Morice, E and Mulligan, C and Cooke, S and Vanes, L and Dunlevy, L and Sharpe, PT and Brandner, S and Henderson, DJ and Nizetic, D and Mohun, T and Bliss, TVP and Fisher, EMC An aneuploid mouse with a human chromosome modelling Down syndrome. In: (Proceedings) Mouse molecular genetics meeting.

Tybulewicz, VLJ and O'Doherty, A and Ruf, S and Mulligan, C and Morice, E and Cooke, S and Vanes, L and Dunlevy, L and Mohun, T and Sharpe, PT and Brandner, S and Bliss, TVP and Henderson, DJ and Nizetic, D and Fisher, EMC An aneuploid mouse with a human chromosome modelling Down syndrome. In:

Tybulewicz, VLJ and Wiseman, F and Watson, S and Lana-Elola, E and Ruparelia, A and Fisher, EMC An unusual mouse modelling aspects of Down syndrome. In: (Proceedings) Genetics Society - Spring Meeting 2010.

Tybulewicz, VLJ and Wiseman, F and Watson, S and Lana-Elola, E and Ruparelia, A and Fisher, EMC An unusual mouse modelling aspects of Down Syndrome. In: (Proceedings) UK-China mouse functional genomics workshop.

Tybulewicz, VLJ and Wiseman, F and Watson, S and Lana-Elola, E and Ruparelia, A and Sheppard, O and Fisher, EMC An unusual mouse modeling aspects of Down syndrome. In: (Proceedings) Cellular and Integrative Neuroscience Themed Meeting.

Tybulewicz, VLJ and Wiseman, F and Watson, S and Lana-Elola, E and Ruparelia, A and Sheppard, O and Fisher, EMC An unusual mouse modeling aspects of Down syndrome. In: (Proceedings) Cellular and Integrative Neuroscience Themed Meeting.

Tymowska-Lalanne, Z and Nolan, PM and Peters, J and Vizor, L and Strivens, M and Washbourne, R and Hough, T and Glenister, P and Thornton, C and Greenaway, S and Hewitt, M and Liu, X and McCormack, S and Selley, R and Wells, C and Roby, P and Martin, J and Fisher, EMC and Rogers, D and Hagan, J and Reaveill, C and Gray, I and Wood, J and Spurr, N and Browne, M and Rastan, S and Hunter, J and Brown, SDM Mapping of mutations from the UK mouse mutagenesis screen - towards a mutant map of the mouse. In: (Proceedings) Mouse Molecular Genetics Meeting.

Urwin, H and Authier, A and Nielsen, J and Holm, I and Johannsen, P and Brown, J and Fisher, EMC and Van-der-Zee, J and The-FReJA-Consortium, and Van-Broweckhoven, C and Collinge, J and Brandner, S and Futter, C and Isaacs, AM Disruption of endosomal trafficking and identification of a novel vacuolar pathology in Frontotemporal Dementia with CHMP2B mutations. In: (Proceedings) Society for Neuroscience meeting 2009.

Urwin, H and Authier, A and Nielsen, J and Holm, I and Johannsen, P and Brown, J and Fisher, EMC and Van-der-Zee, J and The-FReJA-Consortium, and Van-Broweckhoven, C and Collinge, J and Brandner, S and Futter, C and Isaacs, AM Disruption of endosomal trafficking in frontotemporal dementia with CHMP2B mutations. In: (Proceedings) EMBO Protein and lipid function in secretion and endocytosis workshop.

Urwin, H and Authier, A and Nielsen, J and Metcalf, D and Froud, K and Holm, I and Johannsen, P and Brown, J and Fisher, EMC and Van-der-Zee, J and The-FReJA-Consortium, and Van-Broeckhoven, C and Collinge, J and Brandner, S and Futter, C and Isaacs, AM Disruption of endosomes-lysosome fusion in frontotemporal dementia with CHMP2B mutations. In: (Proceedings) "Lysosomes in health and disease" The Biochemical Society.

Urwin, H and Authier, A and Nielsen, JE and Metcalf, D and Froud, K and Holm, I and Johannsen, P and Brown, J and Fisher, EMC and van-der-Zee, J and The-FReJA-Consortium, and Van-Brockhoven, C and Collinge, J and Brandner, S and Futter, C and Isaacs, AM Disruption of lysosomal fusion events in frontotemporal dementia with CHMP2B mutations. In: (Proceedings) 68th Harden Conference, Biochemical Society.

Urwin, H and Authier, A and Nielsen, JE and Metclaf, D and Froud, K and Holm, I and Johannsen, P and Brown, J and Fisher, EMC and van der Zee, and The FReJA consortium, and Van Broeckhoven, C and Collinge, J and Brandner, S and Futter, C and Isaacs, AM Disruption of endosomal trafficiking in frontotemporal dementia with CHMP2B mutations. In: (Proceedings) American Society of Neuroscience Annual meeting.

Urwin, H and Neilsen, J and Collinge, J and Fisher, EMC and The-FReJA-Consortium, and Isaacs, A Frontotemporal demential causing CHMP2B mutants mislocalise and lead to aberrant endosomal structures in cell culture. In: (Proceedings) American Society of Neuroscience meeting.

Urwin, H and Neilsen, J and Collinge, J and FReJA-Consortium, and Isaacs, A Frontotemporal dementia-causing mutants produce enlarged endosoal phenotype and alter growth factor trafficking. In: (Proceedings) 6th International Conference on Frontotemporal Dementias.

Van-de-Leemput, J and Chandran, J and Hardy, J and Fisher, EMC and Cai, H and Singleton, A Mutation in inositol 1,4,5-triphosphate receptor type 1 gene is underlying a server movement disorder in mice. In: (Proceedings) NIA retreat.

Van-de-Leemput, J and Chandran, J and Hardy, J and Fisher, EMC and Cai, H and Singleton, A Mutation in inositol 1,4,5-triphosphate receptor type 1 gene underlies a severe movement in disorder in mice. In: (Proceedings) 20th International Mammalian Genome Society.

Ward, C and Mileham, P and Peters, J and Fisher, EMC Phenotypic and genetic characterization of feeble. In: (Proceedings) 7th International Workshop on Human Chromosome 21.

Ward, C and Mileham, P and Peters, J and Fisher, EMC and Martin, JE Feeble - Failure to thrive. In: (Proceedings) 10th International Mouse Genome Conference.

Ward, CL and Fisher, EMC and Peters, J and Martin, JE Phenotypic and genetic characterisation of feeble. In: (Proceedings) British Neuropathological Society Meeting.

Watson, S and Lana-Elola, E and Slender, A and Fisher, EMC and Tybulewicz, VLJ Generation of a mapping panel of mouse strains to identify causative dosage-sensitive genes in Down syndrome. In: (Proceedings) 2nd Aneuploidy Workshop.

Watson, S and Lana-Elola, E and Slender, A and Fisher, EMC and Tybulewicz, VLJ Generation of a mapping panel of mouse strains to identify causative dosage-sensitive genes in Down syndrome. In: (Proceedings) 2nd AnEuploidy workshop.

Wiggins, LM and Stevens, JC and Kuta, A and Fisher, EMC and Van Bartheld, CS Effects of the dynein heavy chain mutation (Loa) on neuronal morphology and survival in cranial nerve nuclei of the heterozygote Loa mouse. In: (Proceedings) Society of Neuroscience Meeting.

Wiggins, LM and Stevens, JC and Kuta, A and Fisher, EMC and von Bartheld, SC Effects of the dynein heavy chain mutation (Loa) on neuronal morphology and survival in cranial nerve nuclei of the heterozygote Loa mouse. In: (Proceedings) American Society of Neuroscience Annual meeting.

Wiggins, LM and Stevens, JC and Kuta, A and Fisher, EMC and von Bartheld, SC Effects of the dynein heavy chain mutation (Loa) on neuronal morphology and survival in cranial nerve nuclei of the heterozygote Loa mouse. In: (Proceedings) American Society of Neuroscience Annual meeting.

Wiseman, F and Barkus, C and Sheppard, O and Taylor, A and Slender, A and Choong, X and Cleverley, K and Pietrzyk, J and Bannerman, D and Tybulewicz, V and Fisher, EMC (2013) Trisomy of chromosome 21 modifies APP pathology in a mouse model. In: (Proceedings) Workshop on Cognition in Down Syndrome - Molecular, Cellular and Behavioral Features and the Promise of Pharmacotherapies.

Wiseman, F and Fiegler, H and Rajan, D and Broughton, T and Carter, N and Fisher, EMC and Tybulewicz, VLJ Characterisation of an AnEUploid mouse which models Down Syndrome. In: (Proceedings) First AnEUploidy Workshop.

Wiseman, F and Sheppard, O and Barkus, C and Choong, X and Slender, A and Taylor, A and Bannerman, D and Tybulewicz, V and Fisher, EMC (2013) Trisomy of chromosome 21 modifies APP pathology in a mouse model. In: (Proceedings) 11th International conference on Alzheimer’s and Parkinson’s disaease.

Wiseman, F and Sheppard, O and Barkus, C and Choong, X and Slender, A and Taylor, A and Bannerman, D and Tybulewicz, V and Fisher, EMC (2012) Trisomy of chromosome 21 modifies APP pathology in a mouse model. In: (Proceedings) Scottish TSE Network November Symposium.

Wiseman, F and Sheppard, O and Barkus, C and Pettigill, P and Ruparelia, A and Slender, A and Bannerman, D and Tybulewicz, V and Fisher, EMC The role of trisomy y of human chromosome 21 in the development of Alzheimer’s disease. In: (Proceedings) International Conference Jerome Lejeune.

Wiseman, F and Sheppard, O and Barkus, C and Pettigill, P and Ruparelia, A and Slender, A and Bannerman, D and Tybulewicz, V and Fisher, EMC The role of trisomy y of human chromosome 21 in the development of Alzheimer’s disease. In: (Proceedings) 12th Annual Alzherimer’s Research Trust Network Conference.

Wiseman, F and Sheppard, O and Barkus, C and Pettingill, P and Ruparelia, A and Slender, A and Bannerman, D and Tybulewicz, V and Fisher, EMC The role of trisomy y of human chromosome 21 in the development of Alzheimer’s disease. In: (Proceedings) 12th Annual Alzherimer’s Research Trust Network Conference.

Wiseman, F and Sheppard, O and Barkus, C and Pettingill, P and Ruparelia, A and Slender, A and Bannerman, D and Tybulewicz, V and Fisher, EMC The role of trisomy y of human chromosome 21 in the development of Alzheimer’s disease. In: (Proceedings) International Conference Jerome Lejeune.

Wiseman, F and Sheppard, O and Barkus, C and Pettingill, P and Ruparelia, A and Slender, A and Taylor, A and Bannerman, D and Tybulewicz, V and Fisher, EMC The role of trisomy of human chromosome 21 in the development of Alzheimer disease. In: (Proceedings) UCL Demnet meeting.

Wiseman, F and Sheppard, O and Barkus, C and Pettingill, P and Ruparelia, A and Slender, A and Taylor, A and Bannerman, D and Tybulewicz, V and Fisher, EMC The role of trisomy of human chromosome 21 in the development of Alzheimer disease. In: (Proceedings) Alzheimer’s Research UK Annaual conference.

Wiseman, F and Sheppard, O and Barkus, C and Pettingill, P and Ruparelia, A and Slender, A and Taylor, A and Bannerman, D and Tybulewicz, V and Fisher, EMC Trisomy of human chromosome 21 and the development of Alzheimer’s disease : a mouse model. In: (Proceedings) UCL Demnet Annual One Day Symposium.

Wiseman, F and Sheppard, O and Barkus, C and Ruparelia, A and Bannerman, D and Tybulewicz, V and FISHER, E The role of trisomy of human chromosome 21 in the development of Alzheimer disease. In: (Proceedings) Biochemical Society Meeting - Models of dementia: the good, the bad and the future.

Wiseman, F and Sheppard, O and Barkus, C and Ruparelia, A and Bannerman, D and Tybulewicz, V and Fisher, EMC The role of trisomy of human chromosome 21 in the development of Alzheimer disease. Models of dementia: the good the bad and the future. In: (Proceedings) Biochemical Society meeting.

Wiseman, F and Sheppard, O and Line, S and Ruparelia, A and Deacon, R and Bannerman, D and Tybulewicz, VLJ and Fisher, EMC The role of trisomy of human chromosome 21 in the development of Alzheimer's disease. In: (Proceedings) 2nd Aneuploidy Workshop.

Wiseman, F and Watson, S and Elola-Lana, E and Sheppard, O and Ruparelia, A and Tybulewicz, V and FISHER, E Engineering new mouse models to understand Alzheimer disease and its relationship to Down syndrome. In: (Proceedings) Biochemical Society meeting - Models of dementia: the good, the bad and the future.

Wiseman, F and Watson, S and Elola-Lana, E and Sheppard, O and Ruparelia, A and Tybulewicz, V and Fisher, EMC Engineering new mouse models to understand Alzheimer disease and its relationship to Down syndrome. Models of dementia: the good the bad and the future. In: (Proceedings) Biochemical Society meeting.

Witherden, AS and Hafezparast, M and Nicholson, SJ and Bermingham, NA and Peters, J and Ball, ST and Rogers, DC and Martin, JE and Fisher, EMC (2001) Mapping of Loa, a mouse motor deficit mutation, to distal chromosome 12. In: Copp, AJ and Fisher, EMC, (eds.) Genetics Research. (pp. 203 - ?).

Witherden, AS and Hafezparast, M and Nicholson, SJ and Bermingham, NA and Peters, J and Ball, ST and Rogers, DC and Martin, JE and Fisher, EMC Mapping of Loa, a mouse motor deficit mutation, to distal chromosome 12. In: (Proceedings) Mouse Molecular Genetics Meeting.

Witherden, AS and Nicholson, SJ and Bermingham, N and Ball, S and Peters, J and Rogers, D and Martin, JE and Fisher, EMC and Hafezparast, M Mapping of the mouse motor neurodegeneration gene Loa (legs at odd angles) and progress towards its cloning. In: (Proceedings) 3rd Workshop on Mouse Molecular Neurogenetics.

Witherden, AS and Nicholson, SJ and Hafezparast, M and Peters, J and Ball, ST and Martin, JE and Rogers, JC and Fisher, EMC (2000) Mapping of Loa, a mouse motor deficit gene, to distal mouse chromosome 12. In: Copp, AJ and Fisher, E, (eds.) Genetics Research.

Witherden, AS and Nicholson, SJ and Hafezparast, M and Peters, J and Ball, ST and Martin, JE and Rogers, JC and Fisher, EMC Mapping of Loa, a mouse motor deficit gene, to distal mouse chromosome 12. In: (Proceedings) 13th International Mouse Genome Conference.

Yu, Y and Kenny, GD and Zhang, L and Fisher, EMC and Gaspar, HB and Lythgoe, MF Investigation of ventriculomegaly in mice deficient for adenosine deaminase, using MRI. In: (Proceedings) UCL Neuroscience Symposium.

Yu, Y and Kenny, GD and Zhang, L and Wells, JA and Fisher, EMC and Gaspar, HB and Lythgoe, MF Investigation of ventriculomegaly in mice deficient for adenosine deaminase using MRI. In: (Proceedings) The International Society for Magnetic Resonance in Medicine.

Yulug, IG and Grimmett, WJ and Johnstone, K and McKie, J and Pollock, PJ and Marrable, A and Scambler, PJ and Fisher, EMC Introducing human chromosome 21 into a mouse embryonal carcinoma cell line. In: (Proceedings) BSDB Meeting.

Yulug, IG and Grimmett, WJ and Johnstone, K and Scambler, PJ and Fisher, EMC Investigating the molecular genetics of trisomy 21 (Down syndrome). In: (Proceedings) Second National Medical Biology Congress.

Yulug, IG and Hernandez, D and Hoyle, J and Egan, S and Fisher, EMC Mapping signal transduction genes in mouse and human. In: (Proceedings) 8th International Mouse Genome Conference.

Yulug, IG and Killary, A and Athwal, R and Fisher, EMC (1994) Creating somatic cell hybrids which respond to the morphogen retinoic acid. In: Genetics Research, Camb. (pp. 160 - ?).

Yulug, IG and Pollock, PJ and Hoyle, J and Hernandez, D and Scambler, PJ and Fisher, EMC Human chromosome 21: new cell lines and PCR products. In: (Proceedings) 4th International Workshop on Chromosome 21.

Yulug, IG and Scambler, P and Fisher, EMC Introducing human chromosome 21 into a mouse embryonal carcinoma cell line by microcell mediated chromosome transfer. In: (Proceedings) BSDB Conference: Retinoic Acid in Development.

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