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Article

Acevedo-Arozena, A; Kalmar, B; Essa, S; Ricketts, T; Joyce, P; Kent, R; ... Fisher, EMC; + view all (2011) A comprehensive assessment of the SOD1(G93A) low-copy transgenic mouse, which models human amyotrophic lateral sclerosis. DIS MODEL MECH , 4 (5) 686 - 700. 10.1242/dmm.007237. Gold open access

Achilli, F; Boyle, S; Kieran, D; Chia, R; Hafezparast, M; Martin, JE; ... Fisher, EMC; + view all (2005) The SOD1 transgene in the G93A mouse model of amyotrophic lateral sclerosis lies on distal mouse chromosome 12. AMYOTROPH LATERAL SC , 6 (2) 111 - 114. 10.1080/14660820510035351.

Achilli, F; Bros-Facer, V; Williams, HP; Banks, GT; AlQatari, M; Chia, R; ... Fisher, EMC; + view all (2009) An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. Disease Models & Mechanisms , 2 (7-8) 359 - 373. 10.1242/dmm.002527. Green and gold open access
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Ahmad-Annuar, A; Shah, P; Hafezparast, M; Hummerich, H; Witherden, AS; Morrison, KE; ... Fisher, EMC; + view all (2003) No association with common Caucasian genotypes in exons 8, 13 and 14 of the human cytoplasmic dynein heavy chain gene (DNCHC1) and familial motor neuron disorders. AMYOTROPH LATERAL SC , 4 (3) 150 - 157.

Ahmad-Annuar, A; Tabrizi, SJ; Fisher, EMC; (2003) Mouse models as a tool for understanding neurodegenerative diseases. CURR OPIN NEUROL , 16 (4) 451 - 458. 10.1097/01.wco.0000084221.82329.29.

Ahmed,; Dhanasekaran,; Tong,; Wiseman, F; Fisher, EMC; Tybulewicz, V; Gardiner,; (2013) Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain. Molecular Genetics and Genomics: an international journal

Ahmed, MM; Dhanasekaran, AR; Tong, S; Wiseman, FK; Fisher, EM; Tybulewicz, VL; Gardiner, KJ; (2013) Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain. Human Molecular Genetics , 22 (9) 1709 -1724. 10.1093/hmg/ddt017. Green and gold open access
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Alford, KA; Slender, A; Vanes, L; Li, Z; Fisher, EMC; Nizetic, D; ... Tybulewicz, VLJ; + view all (2010) Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome. BLOOD , 115 (14) 2928 - 2937. 10.1182/blood-2009-06-227629.

Anstee, QM; Knapp, S; Maguire, EP; Hosie, AM; Thomas, P; Mortensen, M; ... Thomas, HC; + view all (2013) Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition. Nat Commun , 4 2816 - ?. 10.1038/ncomms3816.

Ashworth, A; Lloyd, S; Brown, J; Gydesen, S; Sorensen, SA; Brun, A; ... Collinge, J; + view all (1999) Molecular genetic characterisation of frontotemporal dementia on chromosome 3. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS , 10 93 - 101.

Ateh, DD; Hussain, IK; Mustafa, AH; Price, KM; Gulati, R; Nickols, CD; ... Martin, JE; + view all (2008) Dynein-dynactin complex subunits are differentially localized in brain and spinal cord, with selective involvement in pathological features of neurodegenerative disease. NEUROPATH APPL NEURO , 34 (1) 88 - 94. 10.1111/j.1365-2990.2007.00924.x.

Banks, G.T.; Bros-Facer, V.; Williams, H.P.; Chia, R.; Achilli, F.; Bryson, J.B.; ... Fisher, E.M.C.; + view all (2009) Mutant glycyl-tRNA synthetase (Gars) ameliorates SOD1G93A motor neuron degeneration phenotype but has little affect on Loa dynein heavy chain mutant mice. PLoS ONE , 4 (7) , Article e6218. 10.1371/journal.pone.0006218. Green and gold open access
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Banks, GT; Bros-Facer, V; Williams, HP; Chia, R; Achilli, F; Bryson, JB; ... Fisher, EMC; + view all (2009) Mutant Glycyl-tRNA Synthetase (Gars) Ameliorates SOD1(G93A) Motor Neuron Degeneration Phenotype but Has Little Affect on Loa Dynein Heavy Chain Mutant Mice. PLOS ONE , 4 (7) , Article e6218. 10.1371/journal.pone.0006218. Green and gold open access
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Banks, GT; Fisher, EMC; (2008) Cytoplasmic dynein could be key to understanding neurodegeneration. GENOME BIOL , 9 (3) , Article 214. 10.1186/gb-2008-9-3-214. Gold open access

Banks, GT; Haas, MA; Line, S; Shepherd, HL; AlQatari, M; Stewart, S; ... Fisher, EMC; + view all (2011) Behavioral and Other Phenotypes in a Cytoplasmic Dynein Light Intermediate Chain 1 Mutant Mouse. J NEUROSCI , 31 (14) 5483 - 5494. 10.1523/JNEUROSCI.5244-10.2011. Gold open access

Banks, GT; Kuta, A; Isaacs, AM; Fisher, EMC; (2008) TDP-43 is a culprit in human neurodegeneration, and not just an innocent bystander. MAMM GENOME , 19 (5) 299 - 305. 10.1007/s00335-008-9117-x. Gold open access

Beck, JA; Lloyd, S; Hafezparast, M; Lennon-Pierce, M; Eppig, JT; Festing, MFW; Fisher, EMC; (2000) Genealogies of mouse inbred strains. NAT GENET , 24 (1) 23 - +.

Becker, EBE; Olivera, PL; Glitsch, MD; Banks, GT; Achilli, F; Hardy, A; ... Davies, KE; + view all (2009) A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice. P NATL ACAD SCI USA , 106 (16) 6706 - 6711. 10.1073/pnas.0810599106.

Bermingham, N; Gilmour, F; Martin, JE; Fisher, EMC; (1995) Human glial cell line-derived neurotrophic factor (GDNF) maps to chromosome 5. Hum Genet , 96 671 - 673.

Bermingham, N; Hernandez, D; Balfour, A; Gilmour, F; Martin, JE; Fisher, EMC; (1995) Mapping TNNC1, the gene which encodes cardiac troponin I in the human and the mouse. Genomics , 30 620 - 622.

Bermingham, N; Martin, JE; Fisher, EMC; (1996) The mouse lysosomal membrane protein 1 gene as a candidate for the motorneuron degeneration (mnd) locus. Genomics , 32 266 - 271.

Bermingham, N; McKay, T; Hoyle, J; Hernandez, D; Martin, JE; Fisher, EMC; (1996) The gene encoding tripeptidyl peptidase II maps to chromosome 1 in the mouse. Mamm Genome , 7 390 - ?.

Bermingham, NA; Rauf, S; Katsanis, N; Martin, JE; Hunter, AJ; Fisher, EMC; (1998) The immunophilin FKBP4 (FKBP52/FKBP59) maps to the distal short arm of human chromosome 12. Mamm Genome , 9 268 - ?.

Bowen, S; Ateh, DD; Deinhardt, K; Bird, MM; Price, KM; Baker, CS; ... Martin, JE; + view all (2007) The phagocytic capacity of neurones. EUR J NEUROSCI , 25 (10) 2947 - 2955. 10.1111/j.1460-9568.2007.05554.x.

Brockdorff, N; Cross, GS; Cavanna, JS; Fisher, EMC; Lyon, MF; Davies, KE; Brown, SDM; (1987) The mapping of a cDNA from the human X linked Duchenne muscular dystrophy gene to the mouse X chromosome. Nature , 328 166 - 168.

BROCKDORFF, N; FISHER, EMC; CAVANNA, J; LYON, MF; BROWN, SDM; (1987) THE MOLECULAR MAPPING OF THE MOUSE X-CHROMOSOME. GENET RES , 49 (3) 258 - 258.

BROCKDORFF, N; FISHER, EMC; CAVANNA, JS; LYON, MF; BROWN, SDM; (1987) CONSTRUCTION OF A DETAILED MOLECULAR MAP OF THE MOUSE X-CHROMOSOME BY MICROCLONING AND INTERSPECIFIC CROSSES. EMBO J , 6 (11) 3291 - 3297.

BROCKDORFF, N; FISHER, EMC; ORKIN, SH; LYON, MF; BROWN, SDM; (1988) LOCALIZATION OF THE HUMAN X-LINKED GENE FOR CHRONIC GRANULOMATOUS-DISEASE TO THE MOUSE X-CHROMOSOME - IMPLICATIONS FOR X-CHROMOSOME EVOLUTION. CYTOGENET CELL GENET , 48 (2) 124 - 125.

Brown, J; Gydesen, S; Johannsen, P; Gade, A; Skibinski, G; Chakrabarti, L; ... FreJA,; + view all (2004) Frontotemporal dementia linked to chromosome 3. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS , 17 (4) 274 - 276. 10.1159/000077153.

BROWN, SDM; BROCKDORFF, N; CAVANNA, JS; FISHER, EMC; GREENFIELD, AJ; LYON, MF; NASIR, J; (1988) THE LONG-RANGE MAPPING OF MAMMALIAN CHROMOSOMES. CURR TOP MICROBIOL , 137 3 - 12.

Canzonetta, C; Mulligan, C; Deutsch, S; Ruf, S; O'Doherty, A; Lyle, R; ... Nizetic, D; + view all (2008) DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome. AM J HUM GENET , 83 (3) 388 - 400. 10.1016/j.ajhg.2008.08.012.

Chakrabarti, L; FReJA,; (2001) Clinical and molecular characterisation of frontotemporal dementia linked to human chromosome 3. AMERICAN JOURNAL OF HUMAN GENETICS , 69 (4) 278 - 278.

Chia, R; Achilli, F; Festing, MFW; Fisher, EMC; (2005) The origins and uses of mouse outbred stocks. NAT GENET , 37 (11) 1181 - 1186. 10.1038/ng1665.

Chia, R; Tattum, MH; Jones, S; Collinge, J; Fisher, EMC; Jackson, GS; (2010) Superoxide Dismutase 1 and tgSOD1(G93A) Mouse Spinal Cord Seed Fibrils, Suggesting a Propagative Cell Death Mechanism in Amyotrophic Lateral Sclerosis. PLOS ONE , 5 (5) , Article e10627. 10.1371/journal.pone.0010627. Green and gold open access
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Chio, A; Schymick, JC; Restagno, G; Scholz, SW; Lombardo, F; Lai, SL; ... Traynor, BJ; + view all (2009) A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. HUM MOL GENET , 18 (8) 1524 - 1532. 10.1093/hmg/ddp059.

Cleary, JO; Wiseman, FK; Norris, FC; Price, AN; Choy, M; Tybulewicz, VLJ; ... Lythgoe, MF; + view all (2011) Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain. NEUROIMAGE , 56 (3) 974 - 983. 10.1016/j.neuroimage.2011.01.082.

Cole, SE; Wiltshire, T; Rue, EE; Morrow, D; Hieter, P; Brahe, C; ... Reeves, RH; + view all (1999) High-resolution comparative physical mapping of mouse Chromosome 10 in the region of homology with human Chromosome 21. Mammalian Genome , 10 (3) 229 - 234.

Cortese, A; Plagnol, V; Brady, S; Simone, R; Lashley, T; Acevedo-Arozena, A; ... Fratta, P; + view all (2014) Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy. Neurobiology of Aging , 35 (6) pp. 1491-1498. 10.1016/j.neurobiolaging.2013.12.029. Green and gold open access
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Curtin, JA; Quint, E; Tsipouri, V; Arkell, RM; Cattanach, B; Copp, AJ; ... Murdoch, JN; + view all (2003) Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. CURR BIOL , 12 (13) 1129 - 1133. 10.1016/S0960-9822(03)00374-9.

De Vita, S; Canzonetta, C; Mulligan, C; Delom, F; Groet, J; Baldo, C; ... Nizetic, D; + view all (2010) Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome. ONCOGENE , 29 (46) 6102 - 6114. 10.1038/onc.2010.351.

Deng, W; Garrett, C; Dombert, B; Soura, V; Banks, G; Fisher, EMC; ... Hafezparast, M; + view all (2011) Neurodegenerative mutation in cytoplasmic dynein alters its organization and dynein-dynactin and dynein-kinesin interactions. J Biol Chem , 285 (51) 39922 - 39932.

Devoy, A; Bunton-Stasyshyn, RK; Tybulewicz, VL; Smith, AJ; Fisher, EM; (2012) Genomically humanized mice: technologies and promises. Nat Rev Genet , 13 (1) 14 - 20. 10.1038/nrg3116.

Doherty, AMO; Fisher, EMC; (2003) Microcell-mediated chromosome transfer (MMCT): small cells with huge potential. MAMM GENOME , 14 (9) 583 - 592. 10.1007/s00335-003-4002-0.

Duchon, A; Pothion, S; Brault, V; Sharp, AJ; Tybulewicz, VLJ; Fisher, EMC; Herault, Y; (2011) The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome. BEHAV BRAIN RES , 217 (2) 271 - 281. 10.1016/j.bbr.2010.10.023.

Dunlevy, L; Bennett, M; Slender, A; Lana-Elola, E; Tybulewicz, VL; Fisher, EMC; Mohun, T; (2010) Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse. CARDIOVASC RES , 88 (2) 287 - 295. 10.1093/cvr/cvq193.

El-Kadi, AM; Bros-Facer, V; Deng, WH; Philpott, A; Stoddart, E; Banks, G; ... Hafezparast, M; + view all (2010) The Legs at odd angles (Loa) Mutation in Cytoplasmic Dynein Ameliorates Mitochondrial Function in SOD1(G93A) Mouse Model for Motor Neuron Disease. J BIOL CHEM , 285 (24) 18627 - 18639. 10.1074/jbc.M110.129320. Gold open access

Festing, MFW; Fisher, EMC; (2000) Mighty mice - Clarence Little's brainwave gave biomedical researchers their best friend. NATURE , 404 (6780) 815 - 815.

Filimonenko, M; Stuffers, S; Raiborg, C; Yamamoto, A; Malerod, L; Fisher, EMC; ... Simonsen, A; + view all (2007) Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. J CELL BIOL , 179 (3) 485 - 500.

Fisher, EMC; (2003) The mouse: genetics and genome. Genetics Society Newsletter , 50 7 - 9.

Fisher, EMC; (1998) Modelling motor neuron degenerative disease. Neuropathol. Appl. Neurobiol. , 24 90 - ?.

Fisher, EMC; (1997) The contribution of the mouse to advances in human genetics. Advances in Genetics , 35 155 - 205. 10.1016/S0065-2660(08)60450-2.

Fisher, EMC; (1995) Why aren't we all bacteria. Immunology News , 2 100 - 103.

Fisher, EMC; (1993) Much ado about cloning. BMJ , 307 (6911) 1074 - 1075.

Fisher, EMC; (1993) Working with the media. Physiological Society Magazine , 8 25 - 25.

Fisher, EMC; (1991) On air. Science and Public Affairs , 1 5 - 6.

Fisher, EMC; Alitalo, T; Luoh, SW; de-la-Chapelle, A; Page, DC; (1990) Human sex-chromosome-specific repeats within a region of pseudoautosomal/Yq homology. Genomics , 7 625 - 628.

Fisher, EMC; Beer-Romero, P; Brown, LG; Ridley, A; McNeil, JA; Bentley-Lawrence, J; ... Page, DC; + view all (1990) Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome. Cell , 63 1205 - 1218.

FISHER, EMC; CAVANNA, JS; BROCKDORFF, N; LYON, MF; BROWN, SDM; (1986) THE MOLECULAR MAPPING OF THE MOUSE X-CHROMOSOME. HEREDITY , 57 286 - 286.

Fisher, EMC; Cavanna, JS; Brown, SDM; (1985) Microdissection and microcloning of the mouse X chromosome. Proc. Natl. Acad. Sci. , 82 5846 - 5849.

Fisher, EMC; Lana-Elola, E; Watson, SD; Vassiliou, G; Tybulewicz, VLJ; (2009) New approaches for modelling sporadic genetic disease in the mouse. DIS MODEL MECH , 2 (9-10) 446 - 453. 10.1242/dmm.001644. Gold open access

Fisher, EMC; Scambler, PJ; (1994) Human haploinsufficiency - one for sorrow, two for joy. Nature Genetics , 7 5 - 7.

Fisher, EMC; Telling, G; Collinge, J; (1998) Prions and the prion disorders. Mamm Genome , 9 (7) 497 - 502.

Fisher, EMC; Tybulewicz, VLJ; (2006) Understanding Down Syndrome. Science and Public Affairs , 9

Fratta, P; Charnock, J; Collins, T; Devoy, A; Howard, R; Malaspina, A; ... Fisher, EM; + view all (2013) Profilin1 E117G is a moderate risk factor for amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry , 85 pp. 506-508. 10.1136/jnnp-2013-306761. Green and gold open access
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Fratta, P; Collins, T; Pemble, S; Nethisinghe, S; Devoy, A; Giunti, P; ... Fisher, EM; + view all (2013) Sequencing analysis of the spinal bulbar muscular atrophy CAG expansion reveals absence of repeat interruptions. Neurobiol Aging 10.1016/j.neurobiolaging.2013.07.015.

Fratta, P; Hanna, MG; Fisher, EM; Sidle, K; (2013) An unusual presentation for SOD1-ALS: Isolated facial diplegia. Muscle Nerve 10.1002/mus.23958.

Fratta, P; Malik, B; Gray, A; La Spada, AR; Hanna, MG; Fisher, EM; Greensmith, L; (2013) FUS is not dysregulated by the spinal bulbar muscular atrophy androgen receptor polyglutamine repeat expansion. Neurobiology of Aging , 34 (5) 1516.e17 - 1516.e19. 10.1016/j.neurobiolaging.2012.09.008. Green and gold open access
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Fratta, P; Mizielinska, S; Nicoll, AJ; Zloh, M; Fisher, EM; Parkinson, G; Isaacs, AM; (2012) C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes. Scientific Reports , 2 , Article 1016 . 10.1038/srep01016. Green and gold open access
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Fratta, P; Nirmalananthan, N; Masset, L; Skorupinska, I; Collins, T; Cortese, A; ... Hanna, MG; + view all (2014) Correlation of clinical and molecular features in spinal bulbar muscular atrophy. Neurology 10.1212/WNL.0000000000000507.

Fratta, P; Poulter, M; Lashley, T; Rohrer, JD; Polke, JM; Beck, J; ... Mead, S; + view all (2013) Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia. Acta Neuropathologica , 126 (3) pp. 401-409. 10.1007/s00401-013-1147-0. Green and gold open access
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Galante, M; Jani, H; Vanes, L; Daniel, H; Fisher, EMC; Tybulewicz, VLJ; ... Morice, E; + view all (2009) Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome. HUM MOL GENET , 18 (8) 1449 - 1463. 10.1093/hmg/ddp055.

Galante, M.; Jani, H.; Vanes, L.; Daniel, H.; Fisher, E.M.C.; Tybulewicz, V.L.J.; ... Morice, E.; + view all (2009) Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome. Human Molecular Genetics , 18 (8) pp. 1449-1463. 10.1093/hmg/ddp055. Green open access
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Garrett, CA; Barri, M; Kuta, A; Soura, V; Deng, W; Fisher, EM; ... Hafezparast, M; + view all (2014) DYNC1H1 mutation alters transport kinetics and ERK1/2-cFos signalling in a mouse model of distal spinal muscular atrophy. Brain , 137 (Pt 7) 1883 - 1893. 10.1093/brain/awu097.

Ghazi-Noori, S; Froud, KE; Mizielinska, S; Powell, C; Smidak, M; Fernandez de Marco, M; ... Isaacs, AM; + view all (2012) Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice. Brain , 135 (Pt 3) 819 - 832. 10.1093/brain/aws006.

Gribble, SM; Wiseman, FK; Clayton, S; Prigmore, E; Langley, E; Yang, F; ... Carter, NP; + view all (2013) Massively Parallel Sequencing Reveals the Complex Structure of an Irradiated Human Chromosome on a Mouse Background in the Tc1 Model of Down Syndrome. PLOS ONE , 8 (4) , Article e60482. 10.1371/journal.pone.0060482. Green and gold open access
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Grizenkova, J; Akhtar, S; Hummerich, H; Tomlinson, A; Asante, EA; Wenborn, A; ... Lloyd, SE; + view all (2012) Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice. Proc Natl Acad Sci U S A , 109 (34) 13722 - 13727. 10.1073/pnas.1208917109. Gold open access

Gydesen, S; Brown, JM; Brun, A; Chakrabarti, L; Gade, A; Johannsen, P; ... Sorensen, SA; + view all (2004) Chromosome 3 linked frontotemporal dementia (FTD-3). Dementia Review (1/2004)

Gydesen, S; Brown, JM; Brun, A; Chakrabarti, L; Gade, A; Johannsen, P; ... Sorensen, SA; + view all (2002) Chromosome 3 linked frontotemporal dementia (FTD-3). NEUROLOGY , 59 (10) 1585 - 1594.

Haas, MA; Bell, D; Slender, A; Lana-Elola, E; Watson-Scales, S; Fisher, EMC; ... Guillemot, F; + view all (2013) Alterations to Dendritic Spine Morphology, but Not Dendrite Patterning, of Cortical Projection Neurons in Tc1 and Ts1Rhr Mouse Models of Down Syndrome. Plos One , 8 (10) , Article e78561. 10.1371/journal.pone.0078561. Green and gold open access
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Hafezparast, M; Ahmad-Annuar, A; Hummerich, H; Shah, P; Ford, M; Baker, C; ... Fisher, EMC; + view all (2003) Paradigms for the identification of new genes in motor neuron degeneration. AMYOTROPH LATERAL SC , 4 (4) 249 - 257. 10.1080/14660820310016084.

Hafezparast, M; Ahmad-Annuar, A; Wood, NW; Tabrizi, SJ; Fisher, EMC; (2003) Mouse models for neurological disease. Adv Clin Neurosci , 13 305 - ?.

Hafezparast, M; Ahmad-Annuar, A; Wood, NW; Tabrizi, SJ; Fisher, EMC; (2002) Mouse models for neurological disease. LANCET NEUROL , 1 (4) 215 - 224.

Hafezparast, M; Ball, S; Nicholson, SJ; Witherden, A; Arac, D; Broadway, N; ... Fisher, EMC; + view all (2002) A new mouse mutant, skijumper. MAMM GENOME , 13 (7) 359 - 364. 10.1007/s003350030008.

Hafezparast, M; Brandner, S; Linehan, J; Martin, JE; Collinge, J; Fisher, EMC; (2005) Prion disease incubation time is not affected in mice heterozygous for a dynein mutation. BIOCHEM BIOPH RES CO , 326 (1) 18 - 22. 10.1016/j.bbrc.2004.10.206.

Hafezparast, M; Fisher, EMC; (1999) Polyglutamine diseases. Trend Genet , 15 222 - ?.

Hafezparast, M; Fisher, EMC; (1998) Wasted by an elongation factor. Trends Genet , 14 215 - 217.

Hafezparast, M; Klocke, R; Ruhrberg, C; Marquardt, A; Ahmad-Annuar, A; Bowen, S; ... Fisher, EMC; + view all (2003) Mutations in dynein link motor neuron degeneration to defects in retrograde transport. SCIENCE , 300 (5620) 808 - 812.

Hafezparast, M; Witherden, A; Nicholson, S; Bermingham, N; Mackin, J; ten Asbroek, A; ... Fisher, EMC; + view all (1999) The kinesin light chain gene: its mapping and exclusion in mouse and human forms of inherited motor neuron degeneration. NEUROSCI LETT , 273 (1) 49 - 52.

Hafezparast, M.; Klocke, R.; Ruhrberg, C.; Marquardt, A.; Ahmad-Annuar, A.; Bowen, S.; ... Fisher, E.M.C.; + view all (2003) Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science , 300 (5620) pp. 808-812. 10.1126/science.1083129.

Hamvas, RMJ; Zinn, A; Keer, JT; Fisher, EMC; Beer-Romero, P; Brown, SDM; Page, D; (1992) Rps4 maps near the inactivation center on the mouse X chromosome. Genomics , 12 363 - 367.

Hernandez, D; Fisher, EMC; (1999) Mouse autosomal trisomy - two’s company, three’s a crowd. Trends in Genetics , 15 241 - 247.

Hernandez, D; Fisher, EMC; (1996) Down syndrome genetics: unravelling a multifactorial disorder. Hum Mol Genet , 5 1411 - 1416.

Hernandez, D; Mee, PJ; Martin, JE; Tybulewicz, VLJ; Fisher, EMC; (1999) Transchromosomal mouse embryonic stem cell lines that contain a freely segregating whole or partial human chromosome 21. Human Molecular Genetics , 8 (5) 923 - 933.

Hernandez, D; Pannett, A; Tybulewicz, V; Fisher, EMC; (1995) Highly polymorphic sequence at D21S1448 mapping close to D21S55. Hum Genet , 95 721 - 722.

Hernandez, D; Yulug, IG; Egan, SE; Fisher, EMC; (1994) Mapping the gene which encodes phosphatidylinositol specific phospholipase C-g 2 in the human and the mouse. Genomics , 23 504 - 507.

Holm, IE; Isaacs, AM; Mackenzie, IRA; FReJA-Consortium,; (2009) Absence of FUS-immunoreactive pathology in frontotemporal dementia linked to chromosome 3 (FTD-3) caused by mutation in the CHMP2B gene. Acta Neuropathologica , 118 719 - 720.

Holme, IE; Englund, E; Mackenzie, IRA; Johannsen, P; Isaacs, AM; The-FReJA-Consortium,; (2007) A reassessment of the neuropathology of frontotemporal dementia linked to chromosome 3. J. Neuropathol. Exp. Neurol , 66 884 - 891.

Hough, TA; Nolan, PM; Tsipouri, V; Toye, AA; Gray, IC; Goldsworthy, M; ... Hunter, AJ; + view all (2002) Novel phenotypes identified by plasma biochemical screening in the mouse. MAMM GENOME , 13 (10) 595 - 602. 10.1007/s00335-002-2188-1.

Hough, TA; Polewski, M; Johnson, K; Cheeseman, M; Nolan, PM; Vizor, L; ... Brown, SDM; + view all (2007) Novel mouse model of autosomal semidominant adult Hypophosphatasia has a splice site mutation in the tissue nonspecific alkaline phosphatase gene Akp2. J BONE MINER RES , 22 (9) 1397 - 1407.

Hoyle, J; Fisher, EMC; (1996) Genomic organization and mapping of the mouse P26s4 ATPase gene: a member of the remarkably conserved AAA gene family. Genomics , 31 115 - 118.

Hoyle, J; Phelan, JP; Bermingham, N; Fisher, EMC; (1996) Localization of human and mouse N-ethylmaleimide-sensitive factor (NSF) gene: a two domain member of the AAA family which is involved in membrane fusion. Mamm Genome , 7 850 - ?.

Hoyle, J; Tan, KH; Fisher, EMC; (1997) Localization of genes encoding two human one domain members of the AAA family: PSMC5 (the thyroid hormone receptor interacting protein, TRIP1) and PSMC3 (the Tat binding protein, TBP1). Hum Genet , 99 285 - 288.

Hoyle, J; Tan, KH; Fisher, EMC; (1997) Mapping human and mouse valosin containing protein (VCP) sequences. Mamm. Genome , 8 778 - 780.

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Wang, Y; Mulligan, C; Denyer, G; Delom, F; Dagna-Bricarelli, F; Tybulewicz, VLJ; ... Groet, J; + view all (2009) Quantitative Proteomics Characterization of a Mouse Embryonic Stem Cell Model of Down Syndrome. MOL CELL PROTEOMICS , 8 (4) 585 - 595. 10.1074/mcp.M800256-MCP200.

Ward, CL; Fisher, EMC; Ball, ST; Peters, J; Martin, JE; (1999) Novel mouse mutant with motor dysfunction from phenotype to genotype. J PATHOL , 187 23A - 23A.

Washbourne, R; Nolan, P; Peters, J; Vizor, L; Hewitt, M; Sellley, R; ... Brown, S; + view all (2000) Identification of novel behavioural mutations using ENU mutagenesis. EUR J NEUROSCI , 12 235 - 235.

Wiggins, LM; Kuta, A; Stevens, JC; Fisher, EMC; von Bartheld, CS; (2012) A Novel Phenotype for the Dynein Heavy Chain Mutation Loa: Altered Dendritic Morphology, Organelle Density, and Reduced Numbers of Trigeminal Motoneurons. JOURNAL OF COMPARATIVE NEUROLOGY , 520 (12) 2757 - 2773. 10.1002/cne.23085.

Wills, AM; Cronin, S; Slowik, A; Kasperaviciute, D; Van Es, MA; Morahan, JM; ... Brown, RH; + view all (2009) A large-scale international meta-analysis of paraoxonase gene polymorphisms in sporadic ALS. NEUROLOGY , 73 (1) 16 - 24. 10.1212/WNL.0b013e3181a18674.

Wilson, MD; Barbosa-Morais, NL; Schmidt, D; Conboy, CM; Vanes, L; Tybulewicz, VLJ; ... Odom, DT; + view all (2008) Species-specific transcription in mice carrying human chromosome 21. SCIENCE , 322 (5900) 434 - 438. 10.1126/science.1160930.

Wiseman, FK; Alford, KA; Tybulewicz, VLJ; Fisher, EMC; (2009) Down syndrome-recent progress and future prospects. HUM MOL GENET , 18 R75 - R83. 10.1093/hmg/ddp010. Green and gold open access
file

Wiseman, FK; Sheppard, O; Linehan, JM; Brandner, S; Tybulewicz, VL; Fisher, EM; (2010) Generation of a panel of antibodies against proteins encoded on human chromosome 21. J Negat Results Biomed , 9 7 - ?. 10.1186/1477-5751-9-7.

Witherden, AS; Hafezparast, M; Nicholson, SJ; Ahmad-Annuar, A; Bermingham, N; Arac, D; ... Fisher, EMC; + view all (2002) An integrated genetic, radiation hybrid, physical and transcription map of a region of distal mouse chromosome 12, including an imprinted locus and the 'Legs at odd angles' (Loa) mutation. GENE , 283 (1-2) 71 - 82.

Witherden, AS; Nicholson, SJ; Fisher, EMC; (1997) The value of mouse mutants. Mouse Genome , 95 856 - 874.

Yulug, IG; Egan, SE; Pollock, PM; Fisher, EMC; (1993) A homologue of the Drosophila Son of Sevenless gene maps to mouse chromosome 17. Genomics , 18 733 - 734.

Yulug, IG; Egan, SE; See, CG; Fisher, EMC; (1995) Mapping human SHC, a gene that encodes an adaptor protein and identifying and mapping a SHC related sequence. Hum. Genet. , 96 245 - 248.

Yulug, IG; Egan, SE; See, CG; Fisher, EMC; (1994) Mapping GRB2, a signal transduction gene in the human and the mouse. Genomics , 22 313 - 318.

Yulug, IG; Fisher, EMC; (1995) The frequency and position of Alu repeats in cDNAs, as determined by database searching. Genomics , 27 544 - 548.

Yulug, IG; Hillermann, R; Fisher, EMC; (1994) The SHB adaptor protein maps to human chromosome 9. Genomics , 24 615 - 617.

Yulug, IG; Katsanis, N; de-Belleroche, J; Collinge, J; Fisher, EMC; (1995) An improved protocol for the analysis of SOD1 gene mutations, and a new mutation in exon 4. Hum Mol Genet , 4 1101 - 1104.

Yulug, IG; Killary, AM; Sandhu, AK; Athwal, RS; Fox, M; Fisher, EMC; (1995) Gene expression in response to retinoic acid in novel human chromosome 21 monochromosomal cell hybrids. SOMAT CELL MOLEC GEN , 21 (5) 357 - 365.

Yulug, IG; See, CG; Fisher, EMC; (1995) The DAD1 protein, whose defect causes apoptotic cell death, maps to human chromosome 14. Genomics , 26 433 - 435.

Zinn, AR; Page, DC; Fisher, EMC; (1993) Turner syndrome: the case of the missing sex chromosome. Trends Genet , 9 90 - 93.

Book

UNSPECIFIED (Ed). (1998) Methods in Mouse Genetics and Genome Mapping. Academic Press: New York.

UNSPECIFIED (Ed). Enjoy writing your science thesis or dissertation. Imperial College Press: London UK.

Book chapter

Ballabio, A; Brown, SDM; Fisher, EMC; (1997) Strategies for disease identification. In: Genome Analysis: A laboratory manual. Cold Spring Harbor Laboratory Press: Cold Spring Harbor.

Fisher, EMC; (1994) Genetics, molecular and cell biology. In: Kumar, PJ and Clark, ML, (eds.) Clinical Medicine. Balliere Tindall: London.

Poster

Hough, T; Fisher, EMC; Cheeseman, M; Hunter, J; Brown, SDM; (2003) Characterisation and genetics of a mouse model of hypophospatasia. Presented at: 17th International Mouse Genome conference, Braunschweig, Germany.

Hough, T; Fisher, EMC; Cheeseman, M; Hunter, J; Brown, SDM; (2003) Characterisation and genetics of a mouse model of hypophospatasia. Presented at: 17th International Mouse Genome conference, Braunschweig, Germany.

Johannsen, P; Gade, A; Brown, J; Chakrabarti, L; Gjedde, A; Gydesen, S; ... FReJA-Consortium,; + view all (2001) Chromosome-3 linked frontotemporal dementia (FTD3) and cerebral blood flow. Presented at: NorAge meeting, Norway.

Johannsen, P; Holm, I; Simon, F; Eskildsen, SF; Rodell, A; Isaacs, AM; ... The-FReJA-Consortium,; + view all (2006) New imaging and pathology findings in FTD-3 patients and mutation carriers. Presented at: 5th International Conference on frontotemporal dementias, San Francisco, USA.

Kara, M; Groet, J; Letourneau, A; Guipponi, M; Santoni, F; Bena, F; ... Nizetic, D; + view all (2013) AN INTACT GENOME, ISOGENIC HIPSC MODEL FROM A MOSAIC DOWN SYNDROME INDIVIDUAL REVEALS NEUROGENESIS AND MITOCHONDRIAL DEFECTS CAUSED BY TRISOMY 21. Presented at: Workshop on Cognition in Down Syndrome - Molecular, Cellular and Behavioral Features and the Promise of Pharmacotherapies, Washington DC, USA.

Lloyd, SE; Onwuazor, ON; Fisher, EMC; Collinge, J; (2000) Quantitative trait locus analysis of prion disease incubation time. Presented at: Join Funders Transmissible Spongiform Encephalopathies workshop, Keele, Uk.

Lloyd, SE; Uphill, JB; Targonski, P; Fisher, EMC; Collinge, J; (2002) Identification of genetic loci affecting bovine spongiform encephalopathy incubation time in mice. Presented at: Joint Funders Transmissible Spongiform Encephalopathies workshop, Durham.

Massand, E; Karmiloff-Smith, A; The LonDownS Consortium,; (2013) Understanding adult outcomes through infancy studies: Neuro-cognitive phenotypes of infants with Down syndrome may predict protective/risk markers for Alzheimer’s disease. Presented at: Workshop on Cognition in Down Syndrome - Molecular, Cellular and Behavioral Features and the Promise of Pharmacotherapies, Washington DC, USA.

Richardson, S; Siow, B; Wells, J; Fisher, EMC; Schiavo, G; Lythgoe, MF; (2010) MRI detection of axonal transport via tetanus neurotoxin bound ixide nanoparticles. Presented at: BCISMRM MR Post-Graduate Meeting, Institute of Psychiatry, Kings College London.

Ruparelia, A; Wiseman, F; Sheppard, O; Kuta, A; Tybulewicz, VLJ; Schiavo, G; Fisher, EMC; (2010) Axonal transport in a panel of mice that model Down syndrome. Presented at: Queen Square Student Symposium, UCL, Institute of Neurology, UCL, London.

Tybulewicz, VLJ; O'Doherty, A; Wiseman, F; Broughton, T; Ruf, S; Mulligan, C; ... Fisher, EMC; + view all (2007) Characterization of an aneuploid mouse with a human chromosome that models Down syndrome. Presented at: Expert workshop on the biology of chromosome 21 genes: Towrds gene-phenotype correlations in Down syndrome, Washington, DC.

Witherden, AS; Hafezparast, M; Nicholson, SJ; Bermingham, N; Ball, S; Peters, J; ... Fisher, EMC; + view all (1999) Mapping of the mouse motor neurodegeneration gene Loa (legs at odd angles) and progress towards its cloning. Presented at: Imperial college School of Medicine Open Day, London, UK.

Zinyuk, LE; Tybulewicz, VLJ; Fisher, EMC; Jones, MW; (2009) Understanding higher brain function and complex disorders using rodent models. Presented at: The 3Rs today, NC£Rs poster event, London, UK.

Proceedings paper

Acevedo-Arozena, A; Corrochano, S; Ricketts, T; Carter, S; Ribinsztein, DC; Fisher, EMC; Brown, SDM; Sensitised ENU screens for Huntingtons Disease and Amyotrophic Lateral Sclerosis. In: (Proceedings) Society for Neuroscience meeting 2009.

Acevedo-Arozena, A; Ricketts, T; Kalmar, B; Kent, R; Greensmith, L; Fisher, EMC; A mutagenesis strategy to find SOD1 ALS modifiers in the mouse. In: (Proceedings) 20th International Symposium on ALS/MND.

Acevedo-Arozena, A; Ricketts, T; Kalmar, B; Kent, R; Greensmith, L; Fisher, EMC; Using ENU mutagenesis to search for modifiers of SOD1 ALS in the mouse. In: (Proceedings) 20th International Symposium on ALS/MND.

Acevedo-Arozena, A; Rowe, C; Fisher, EMC; A mutagenesis strategy to find SOD1 ALS modifiers in the mouse. In: (Proceedings) 6th FENS forum for European Neuroscientists.

Acevedo-Arozena, A; Rowe, C; Fisher, EMC; Searching for SOD1 ALS modifiers in the mouse. In: (Proceedings) International Mammalian Genome Conference.

Achilli, F; Boyle, S; Kieran, D; Chia, R; Hafezparast, M; Martin, JE; ... Fisher, EMC; + view all (2005) The SOD1 transgene in the G93A mouse model of amyotrophic lateral sclerosis lies on distal mouse chromosome 12. In: ALS and Other MNDs.

Achilli, F; Nolan, P; Fisher, EMC; Characterisation of new mice models of motor neuron disease. In: (Proceedings) 18th International Mouse Genome Conference.

Achilli, F; Nolan, P; Lalanne, Z; Hardy, A; Booker, D; Strand, K; ... Fisher, EMC; + view all Characterisation of new locomotor mutants. In: (Proceedings) 19th International Mouse Genome Conference.

Ahmad-Annuar, A; Hafezparast, M; Witherden, A; Ball, S; Hummerich, H; Peters, J; ... Fisher, EMC; + view all Legs at odd angles: a mouse mutant for motor neuron degeneration. In: (Proceedings) Fourth Workshop on Mouse Molecular Genetics.

Ahmad-Annuar, A; Hafezparast, M; Witherden, A; Ball, S; Peters, J; Martin, JE; Fisher, EMC; Legs at odd angles: a mouse mutant with a neuronal deficit. In: (Proceedings) 15th International Mouse Genome conference.

Ahmad-Annuar, A; Shah, P; Hafezparast, M; Goldstein, D; Fisher, EMC; Linkage disequilibrium and haplotype mapping of the human cytoplasmic dynein heavy chain 1 gene. In: (Proceedings) Graduate School of Life Sciences and Medicine Student Symposium, Imperial College.

Ahmad-Annuar, A; Shah, P; Hafezparast, M; Goldstein, DB; Fisher, EMC; (2003) Linkage disequilibrium and haplotype mapping of the human cytoplasmic dynein heavy chain 1 gene on chromosome 14q32. In: AMERICAN JOURNAL OF HUMAN GENETICS. (pp. 487 - 487). UNIV CHICAGO PRESS

Airey, J; Washbourne, R; Peters, J; Vizor, L; Tymowska-Lalanne, Z; Smythe, S; ... Nolan, PM; + view all Analysis of ENU-induced mutations exhibiting an elevated acoustic startle response. In: (Proceedings) 15th International Mouse Genome conference.

Alford, KA; Vanes, L; Fisher, EMC; Tybulewicz, VLJ; A myeloproliferative disorder in the Tc1 mouse model of Down syndrome. In: (Proceedings) Modern trends in human leukemia, Wilsede Meeting XV11.

Alford, KA; Vanes, L; Li, Z; Orkin, SH; Fisher, EMC; Tybulewicz, VLJ; (2008) A Myeloproliferative Disorder in the Tel Mouse Model of Down Syndrome. In: BLOOD. (pp. 964 - 964). AMER SOC HEMATOLOGY

Ali-Morsi, A; Stoddart, E; Bros-Facer, V; Fisher, EMC; Greensmith, L; Hafezparast, M; Investigating why dynein mutation ameliorates the SOD1 ALS phenotype and considerably extends lifespan. In:

AlQatari, M; Vastani, N; Bros-Facer, V; Groves, M; Greensmith, L; Fisher, EM; Koltzenburg, M; (2009) A MUTATION OF THE CYTOPLASMIC DYNEIN HEAVY CHAIN GENE Dync1h1 CAUSES A SEVERE SENSORY NEUROPATHY. In: JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM. (pp. 6 - 6). WILEY-BLACKWELL PUBLISHING, INC

Ateh, DD; Hussain, I; Mustafa, A; Price, KM; Nickols, CD; Bird, MM; ... Martin, JE; + view all (2006) Normal subcellular distribution of dynein-dynactin complex subunits and disturbances in neurodegenerative disease. In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. (pp. 234 - 235). BLACKWELL PUBLISHING

Ateh, DD; Hussain, I; Mustafa, A; Price, KM; Nickols, CD; Bird, MM; ... Martin, JE; + view all (2006) Subcellular functional specificity of dynein-dynactin complex subunits - normal distribution and disturbances in neurodegenerative disease. In: JOURNAL OF PATHOLOGY. (pp. 23A - 23A). JOHN WILEY & SONS LTD

Baker, CS; Price, KM; Bowen, S; Hafezparast, M; Ahmad-Annuar, A; Peters, J; ... Martin, JE; + view all Protein studies of the Loa mutant. In: (Proceedings) 13th International Symposium on ALS/MND.

Baker, CS; Price, KM; Bowen, S; Walker, KE; Chana, S; Fisher, EMC; Martin, JE; (2003) Protein characterisation of the Loa mouse. In: Amyotroph. Lateral Scler Other Motor Neuron Disord. (pp. 5 - 227).

Banks, G; Fisher, EMC; A functional dissection of the dynein complex by genetic screening in mice. In: (Proceedings) EMBO/FEBS Workshop on Systems Dynamics of Intracellular Communications.

Banks, G; Kuta, A; Bros-Facer, V; Schiavo, G; Koltzenburg, M; Greensmith, L; Fisher, EMC; Working with mouse mutants to uncover the roles of transport proteins. In: (Proceedings) EMBO Conference on spatial dynamics of intracellular communication - overcoming distance in signalling networks.

Bermingham, N; Martin, JE; Fisher, EMC; Fine mapping the MND locus and mouse chromosome 8. In: (Proceedings) Mouse Molecular Genetics Meeting.

Bermingham, N; Peters, J; Martin, JE; Fisher, EMC; Characterisation of three new mouse mutants with neuromuscular deficits. In: (Proceedings) Mouse Molecular Neurogenetics Meeting.

Bermingham, N; Peters, J; Martin, JE; Fisher, EMC; Positional cloning of legs at odd angles (Loa). In: (Proceedings) Ninth Mouse Genome meeting.

Bermingham, N; Peters, J; Rogers, D; Martin, J; Fisher, EMC; Positional cloning of the neurological mutant: Legs at odd angles (Loa). In: (Proceedings) Second Mouse Molecular Neurogenetics Meeting.

Bermingham, N; Peters, J; Rogers, D; Martin, J; Fisher, EMC; The neurological mutant: legs at odd angles (Loa). In: (Proceedings) 10th International Mouse Genome Conference.

Bowen, S; Bird, MM; Deinhardt, K; Price, KM; Baker, CS; Robson, JC; ... Martin, JE; + view all Phagocytosis of cell and non-cell debris by neurons in vitro and in vivo. In: (Proceedings) 15th International ALS symposium.

Bros, V; Golding, M; Chia, R; Schiavo, G; Flenniken, A; Adamson, SL; ... Hafezparast, M; + view all The Arl mouse - a new mouse strain with a mutation in the cytoplasmic dynein heavy chain. In: (Proceedings) Mutant SOD1 and ALS: from the molecule to man.

Bros, V; Golding, M; Schiavo, G; Chia, R; Philpott, A; Flenniken, A; ... Hafezparast, M; + view all The Arl mouse - a new mouse strain with a mutation in the cytoplasmic dynein heavy chain. In: (Proceedings) EMBO/FEBS Workshop on Systems Dynamics of Intracellular Communications.

Bros-Facer, V; Baisland, L; Hafezparast, M; Fisher, EMC; Duchen, M; Schiavo, G; Greensmith, L; The effects of a dynein mutation on mitochondria in SOD1 motoneurons. In: (Proceedings) 19th International Symposium on ALS/MND.

Bros-Facer, V; Banks, GT; Williams, H; Greensmith, L; Fisher, EMC; A novel mutation in glycine tRNA synthetase ameliorates SOD1G93A motor neuron degeneration. In: (Proceedings) 19th International Symposium on ALS/MND.

Brown, J; Gydesen, S; Johannsen, P; Gade, A; Skinbinski, G; Chakrabarti, L; ... Collinge, J; + view all Frontotemporal dementia linked to chromosome 3 (FTD3). In: (Proceedings) 14th International Conference on Frontotemporal Dementia.

Brown, J; The-FReJA-Consortium,; Clinical features of frontotemporal demential linked to chromosome 3 - FTD3. In: (Proceedings) 4th International Conference on Frontotemporal Dementia.

Brown, JM; Isaacs, A; Neilsen, J; The-FReJA-Consortium,; Mutations in the endosomal ESCRT-III complex in frontotemporal dementia. In: Alzheimer's & Dementia. (pp. S419 - S419).

Brown, S; Peters, J; Nolan, P; Vizor, L; Thornton, C; Glenister, P; ... Hunter, J; + view all A comprehensive ENU mutagenesis programme for the mouse genome. In: (Proceedings) Mouse molecular genetics.

Brown, S; Peters, J; Vizor, L; Thornton, C; Glenister, P; Greenaway, S; ... Hunter, J; + view all Evaluation of neurological mouse mutants caused by ENU mutagenesis. In: (Proceedings) EMBL Mouse Molecular Genetics Meeting.

Brown, S; Peters, J; Vizor, L; Thornton, C; Glenister, P; Greenaway, S; ... Hunter, J; + view all The mutant map of the mouse. In: (Proceedings) Genome Sequencing and Biology Meeting.

Brown, S; Peters, J; Vizor, L; Thornton, C; Glenister, P; Greenaway, S; ... Hunter, J; + view all A comprehensive ENU mutagenesis programme for the mouse genome. In: Cytogenetics and Cell Genetics.

Brun, A; The-FReJA-Consortium,; Pathology of FTD3. In: (Proceedings) International Conference on Frontotemporal Dementia.

Bunton-Stasyshyn, R; Devoy, A; Fisher, EMC; An investigation into the role of endogenousmouse Sod1 in the disease course of transgenic SOD1mouse models of amyotrophic lateral sclerosis. In: (Proceedings) American Society of Neuroscience Annual meeting.

Bunton-Stasyshyn, R; Devoy, A; Tybulewicz, V; A SOD1 humanising knock-in mouse model fo ALS with conditional point mutation. In: (Proceedings) Queen Square Student Symposium.

Bunton-Stasyshyn, R; Devoy, A; Tybulewicz, V; Fisher, EMC; A SOD1 humanising knock-in mouse model fo ALS with conditional point mutation. In: (Proceedings) Queen Square Student Symposium.

Bunton-Stasyshyn, R; Devoy, A; Tybulewicz, V; Fisher, EMC; A SOD1 humanising knock-in mouse model of ALS with conditional point mutation. In: (Proceedings) UCL Neuroscience Symposium.

Bunton-Stasyshyn, R; Devoy, A; Tybulewicz, VLJ; Fisher, EMC; A SOD1 humansing knock-in mouse model of ALS with conditional point mutation. In: (Proceedings) Mouse Genetics 2011 Conference.

Chakrabarti, L; Association, FFRIJ; Clinical and molecular characterisation of Frontotemporal dementia linked to Human Chromosome 2. In: (Proceedings) American Society of Human Genetics.

Chia, R; Achilli, F; Festing, MFW; Fisher, EMC; (2005) The origins and uses of mouse outbred stocks. In: ALS and Other MNDs.

Chia, R; Achilli, F; Festing, MFW; Fisher, EMC; The origins and uses of mouse outbred stocks. In: (Proceedings) 19th International Mouse Genome Conference.

Chia, R; Tattum, H; Clarke, A; Fisher, EMC; Jackson, GS; In vitro fibrillization of superoxide dismutatse type 1 (SOD1) suggests one possible mechanism by which mutations may lead to amyotrophic lateral sclerosis (ALS). In: (Proceedings) Keystone symposium: Molecular mechanisms of neurodegeneration.

Choong, X; Raha, A; Tybulewicz, V; Wiseman, F; Fisher, EMC; (2013) Identification of genes on Hsa21 influencing APP/A pathology using primary neuronal cultures from transgenic mice. In: (Proceedings) British Neuroscience Association.

Choong, X; Raha, A; Tybulewicz, V; Wiseman, F; Fisher, EMC; (2013) Using primary neurons from transgenic mice to identify genes on human chromosome 21 influencing Alzheimer neuropathology. In: (Proceedings) Alzheimer Association International Conference.

Choong, X; Raha, A; Tybulewicz, V; Wiseman, F; Fisher, EMC; (2013) Which genes on human chromosome 21, other than APP, influence Alzheimer neuropathology? In: (Proceedings) Alzheimers Research UK Annual Conference.

Cleary, J; Price, A; Thayyil, S; Schambler, P; Tybulewicz, VLJ; Fisher, EMC; ... Lythgoe, M; + view all Towards 3D virtual histology using high-field magnetic resonance imaging. In: (Proceedings) British Association of Clinical Anatomists.

Cleary, JO; Norris, FC; Wiseman, FK; Price, AN; Choy, MK; Tybulewicz, VLJ; ... Lythgoe, MF; + view all Optimised μMRI for Phenotyping the Tc1 Model of Down Syndrome. In: (Proceedings) Society for Magnetic Resonance in Medicine.

Cooke, SF; Errington, ML; O'Doherty, A; Sesay, A; Ruf, A; Vanes, L; ... Fisher, EMC; + view all Insertion of human chromosome 21 into the mouse genome leads to impairments of hippocampal LTP and memory. In: (Proceedings) Society for Neuroscience.

Crawford, H; Wiseman, F; Fisher, EMC; Pocock, J; (2013) Clues to Down syndrome and Alzheimer’s disease: investigating microglial behaviour in the Tc1 mouse model. In: (Proceedings) UCL ION Student Symposium.

Curtin, JA; Tsipouri, V; Latham, I; Nolan, P; Hardisty, R; Vizor, L; ... Fisher, EMC; + view all Rapid genome scan reveals linkage to mouse chromosome 15 for the ENU induced circling mouse mutant spin cycle, a potential model for DFNA17. In: (Proceedings) Mouse Initiatives III: Modeling the Human Genome & Disease.

Curtin, JA; Tsipouri, V; Latham, I; Nolan, P; Hardisty, R; Vizor, L; ... Spur, NK; + view all (2001) Rapid genome scan reveals linkage to chromosome 15 for the ENU induced circling mouse mutant, spin cycle. In: Copp, AJ and Fisher, EMC, (eds.) Genetcis Research. (pp. 203 - ?). Cambridge Journals

Delabar, JM; Creau, N; Antonarakis, SE; Brahe, C; Estivill, X; Pritchard, M; ... Lutfalla, G; + view all (1996) Towards an integrated chromosome 21 map: progress of the European chromosome 21 consortium. In: European Journal of Human Genetics.

Delabar, JM; Creau, N; Brahe, C; Fisher, EMC; Kessling, A; Potier, MC; ... Van-Broeckhoven, C; + view all European chromosome 21 consortium: two years achievements. In: European Journal of Human Genetics.

Devoy, A; Bunton-Stasyshyn, R; Tybulewicz, VLJ; Fisher, EMC; Making new mouse models of ALS. In: (Proceedings) 22nd International Symposium on ALS/MND.

Devoy, A; Fratta, P; Fisher, EMC; Making new mouse models of ALS. In: (Proceedings) MRC Centre for Translational Research - Scientific Advisory Board Review.

Devoy, A; Tybulewicz, VLJ; Fisher, EMC; A SOD1 humansing knock-in mouse model of ALS with conditional point mutation. In: (Proceedings) Mouse Genetics 2011 Conference.

Dunlevey, LPE; Fisher, EMC; Tybulewicz, VLJ; Mohun, T; Cardiac development in a mouse model of Down Syndrome (Tc1). In: (Proceedings) ESC WG Developmental Anatomy and Pathology meeting 2009.

Dunlevey, LPE; Fisher, EMC; Tybulewicz, VLJ; Mohun, T; Cardiac development in a mouse model of Down syndrome (Tc1). In: (Proceedings) First AnEUploidy Workshop.

Dunlevy, L; Fisher, EMC; Tybulewicz, VLJ; Mohun, T; Cardiac development in a mouse model of Down Syndrome (Tc1). In: (Proceedings) Weinstein Cardiovascular Development Conference.

Egan, SE; Fisher, EMC; Downward, J; (1994) Transformation by the mSos1 Ras exchange protein. In: J. Cell. Biochem. (pp. 234 - ?).

Errington, ML; Cooke, SF; O'Doherty, A; Ruf, S; Vanes, L; Bliss, TVP; ... Fisher, EMC; + view all Insertion of human chromosome 21 into the mouse genome leads to impairments of memory and hippocampal LTP. In: (Proceedings) British Neuroscience Association.

Farrer, MH; Prasher, VP; Fisher, EMC; Kessling, AM; Phenotype/genotype mapping Alzheimer-type dementia in Down syndrome. In: American Journal of Human Genetics. (pp. 500 - ?).

Farrer, MJ; Fisher, EMC; Kessling, AM; Molecular genetic characterisation of six cases with partial chromosome 21 aneuploidy. In: European Journal of Human Genetics (Supp).

Fisher, EMC; Multiple mouse models for helping us understand ALS. In: (Proceedings) 2nd European ALS Research Workshop.

Fisher, EMC; The genetics of motor neurone disorders. In: (Proceedings) NIGMS Research Symposium Minority program..

Fisher, EMC; Treating hybrid cell lines with retinoic acid. In: (Proceedings) Gordon Research Conference on Developmental Biology.

Fisher, EMC; Alford, K; Dunlevy, L; Lana-Elola, E; Haas, M; Line, S; ... Tybulewicz, VLJ; + view all Recent data on the phenotype of the Tc1 mouse model of Down syndrome. In: (Proceedings) 2nd Aneuploidy Workshop.

Fisher, EMC; Brown, LG; Page, DC; Mapping the human Y chromosome. In: (Proceedings) Gordon Research Conference on Mammalian Gametogenesis and Embryogenesis.

Fisher, EMC; Bunton-Stasyshyn, R; Devoy, A; Tybulewicz, V; A SOD1 humanising knock-in mouse model of ALS with conditional point mutation. In: (Proceedings) Mouse Genetics 2011 Conference.

Fisher, EMC; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) International Society of Differentiation, Differentiation of Normal and Neoplastic Cells.

Fisher, EMC; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) 5th Tenovus Symposium on Eukaryotic genes.

Fisher, EMC; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) Fourth International Workshop on Mouse Molecular Genetics.

Fisher, EMC; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) EMBO/EMBL Molecular Approaches to Stem Cell Differentiation and Mouse Development.

Fisher, EMC; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) Mammalian Genetics Group/Mammalian Biochemical Genetics Group Conference.

Fisher, EMC; Cleary, JO; Norris, FC; Wiseman, FK; Price, AN; Choy, MK; ... Lythgoe, MF; + view all Optimised µMRI for Phenotyping the Tc1 Model of Down Syndrome. In: (Proceedings) Society for Magnetic Resonance in Medicine.

Fisher, EMC; Collins, T; Sheppard, O; Fratta, P; Devoy, A; (2013) Working with mice to help understand motor neuron disease. In: (Proceedings) National Hospital for Neurology and Neurosurgery. MND open day.

Fisher, EMC; Fratta, P; Joyce, P; Ricketts, T; Acevedo, A; Investigating specific transcriptomes in mouse models of amyotrophic lateral sclerosis. In: (Proceedings) EMBO Workshop on Intracellular RNA Localisation and localised translation.

Fisher, EMC; Greenfield, A; Cavanna, J; Brown, SDM; Microdissection of mammalian chromosomes. In: (Proceedings) International Chromosome meeting.

Fisher, EMC; Greenfield, A; Cavanna, J; Brown, SDM; Microdissection of mammalian chromosomes. In: (Proceedings) Mammalian Genetics Group/Mammalian Biochemical Genetics Group Conference.

Fisher, EMC; Greenfield, A; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) Genetical Society Symposium on Molecular Genetics of Animal Development.

Fisher, EMC; Greenfield, A; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) Mammalian Genetics Group/Mammalian Biochemical Genetics Group conference.

Fisher, EMC; Greensmith, L; Investigating why dynein mutation ameliorates the SOD1 ALS phenotype and considerably extends lifespan. In: (Proceedings) 5th Annual Packard Center for ALS Research Symposium.

Fisher, EMC; Grimmett, W; Johnstone, K; McKie, J; O'Donnell, H; Pollock, P; ... Scambler, PJ; + view all Transferring subchromosomal fragments into mouse embryonic carcinoma and stem cells. In: (Proceedings) Mammalian Neurobiology Workshop.

Fisher, EMC; Grimmett, WJ; Johnstone, K; McKie, J; Pollock, PM; Strutt, P; Yulug, IG; A PCR approach to cloning genes from Chromosome 21. In: (Proceedings) 3rd International Workshop on Human Chromosome 21.

Fisher, EMC; Hafezparast, M; Ahmad-Annuar, A; Shah, P; Martin, JE; Models of motor neuron degeneration. In: (Proceedings) 13th International Symposium on ALS/MND.

Fisher, EMC; Johnstone, K; McKie, J; Scambler, PJ; Cell hybrids to isolate genes from human chromosome 21. In: (Proceedings) International Workshop on Chromosome 21..

Fisher, EMC; Joyce, P; Ricketts, T; Fratta, P; Greensmith, L; Acevedo, A; (2010) A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: (Proceedings) 21st International Symposium on ALS/MND.

Fisher, EMC; Martin, JE; (1997) Phenotypic and genotypic characterisation of feeble. In: Neuropathology and Applied Neuropathology.

Fisher, EMC; McGoldrick, P; Joyce, P; Acevedo, A; Greensmith, L; Investigating new mutant models of MND. In: (Proceedings) MRC Centre for Neuromuscular Diseases Annual Meeting.

Fisher, EMC; Page, DC; Characterising the distal short arm of the human Y chromosome. In: (Proceedings) Gordon Research Conference on Molecular Genetics.

Fisher, EMC; Ricketts, T; Fratta, P; Joyce, P; McGoldrick, P; Kent, R; ... Acevedo, A; + view all Characterisation of mouse TDP43 point mutations generated by chemical mutagenesis. In: (Proceedings) 6th Brain Research Conference, RNA-Binding proteins in neurological disease.

Fisher, EMC; Ricketts, T; Fratta, P; Joyce, P; McGoldrick, P; Kent, R; ... Acevedo, A; + view all Characterisation of mouse TDP43 point mutations generated by chemical mutagenesis. In: (Proceedings) American Society of Neuroscience Annual meeting.

Fisher, EMC; Ruparelia, A; Wiseman, F; Sheppard, O; Kuta, A; Tybulewicz, VLJ; Schiavo, G; Axonal transport in a panel of mice that model Down syndrome. In: (Proceedings) Queen Square student symposium, UCL Institute of Neurology.

Fisher, EMC; Sheppard, O; Plattner, F; Rubin, A; Slender, A; Tybulewicz, V; International Conference Jerome Lejeune. In: (Proceedings) International Conference Jerome Lejeune.

Fisher, EMC; Sheppard, O; Plattner, F; Rubin, A; Tybulewicz, V; Wiseman, F; Trisomy of DYRK1A and phosphorylation of tau in a mouse model of Down syndrome. In: (Proceedings) British Neuroscience Association Symposium 'Neurodevelopmental Disorders Across the Lifespan'.

Fisher, EMC; Watson-Scales, S; Lana-Elola, E; Tybulewicz, V; Using chromosome engineering to identify phenotype to genotype relationships in Down syndrome. In: (Proceedings) Mouse Neurological and Behavioural Forum 3.

Fisher, EMC; Wiseman, F; Sheppard, O; Barkus, C; Pettingill, P; Ruparelia, A; ... Tybulewicz, V; + view all The role of trisomy of human chromosome 21 in the development of Alzheimer’s disease. In: (Proceedings) International Conference Jerome Lejeune.

Fisher, EMC; Wiseman, F; Sheppard, O; Barkus, C; Pettingill, P; Ruparelia, A; ... Tybulewicz, V; + view all The role of trisomy of human chromosome 21 in the development of Alzheimer’s disease. In: (Proceedings) 12th Annual Alzherimer’s Research Trust Network Conference.

Fisher, EMC; Wiseman, F; Tybulewicz, V; (2013) Mouse models to understand Down syndrome and Alzheimer disease. In: (Proceedings) Dementia in Intellectual Disability, London Down Syndrome Interest Group meeting.

Fraham-Falkenbert, S; Johannsen, P; Law, I; Jennum, P; Isaacs, A; Brown, J; ... Neilsen, J; + view all changes in regional cerebral glucose metabolism in early symptomatic frontotemporal dementia linked to chromosome 3 (FTD3). In: (Proceedings) Danish Neurological Society meeting.

Fraham-Falkenbert, S; Johannsen, P; Law, I; Jennum, P; Isaacs, A; Brown, J; ... Neilsen, J; + view all Changes in regional cerebral glucose metabolism in early symptomatic frontotemporal dementia linked to chromosome 3 (FTD3). In: (Proceedings) Danish Neurological Society meeting.

Fratta, P; Cortese, A; Plagnol, V; Brady, S; Lashley, T; Simone, R; ... Hanna, M; + view all (2013) Alterations in RNA metabolism in sporadic inclusion body myositis. In: (Proceedings) Association of British Neurologists meeting.

Gade, A; Skibinski, G; Gydesen, S; FReJA-Consortium,; Preclinical signs of impairment in persons at high risk of frontotemporal dementia related to chromosome 3 (FTD3): preliminary findings in neuropsychological tests. In: (Proceedings) 9th International conference on Alzheimer's disease and related disorders.

Gade, A; The-FReJA-Consortium,; FTD3 neuropsychology. In: (Proceedings) 4th International Conference on Frontotemporal Dementia.

Gade, S; Brown, J; Chakrabarti, L; Johannsen, P; Gydesen, S; Association, FFRIJ; Chromosome 3 frontotemporal dementia (FTD-3): clinical course and neuropsychology. In: (Proceedings) International Neuropsychological Society.

Galante, M; Jani, H; Vanes, L; Daniel, H; Fisher, EMC; Tybulewicz, VLJ; ... Morice, E; + view all Analysis of cerebellar function in the Tc1 mouse model of Down syndrome. In: (Proceedings) Synaptic plasticity and repair.

Ghazi-Noori, S; Houghton, R; Fisher, EMC; Collinge, J; Asante, EA; Isaacs, AM; Phenotypic characterization of CHMP2B knockout mice. In: (Proceedings) 6th International Conference on Frontotemporal Dementias.

Ghazi-Noori, S; Stanczak-Mrozek, K; Smidak, M; Powell, C; O'Malley, C; Linehan, JM; ... Isaacs, AM; + view all Phenotypic characterisation of Chmp2b knock out mice. In: (Proceedings) Society for Neuroscience meeting 2009.

Gray, IC; Nolan, PM; Peters, J; Strivens, M; Hough, T; Vizor, L; ... Brown, SDM; + view all New mouse models of human disease. In: (Proceedings) Asia Pacific HUGO meeting.

Grimmett, WJ; Johnstone, K; McKie, J; Strutt, P; Yulug, IG; Scambler, PJ; Fisher, EMC; Cloning genes from chromosome 21. In: European Journal of Human Genetics.

Haas, M; Fisher, E; Tybulewicz, VLJ; Guillemot, F; Cortical projection neuron morphology in the Tc1 and Ts1Rhr modele of Down syndrome. In: (Proceedings) 2nd Aneuploidy Workshop.

Haas, M; Fisher, EMC; Tybulewicz, VLJ; Guillemot, F; Cortical projection neuron morphology in the Tc1 and Ts1Rhr models of Down syndrome. In: (Proceedings) 2nd Aneuploidy Workshop.

Haas, M; Fisher, EMC; Tybulewicz, VLJ; Guillemot, F; Neurogenesis in the developing and adult Tc1 mouse, a model of human Down Syndrome. In: (Proceedings) First AnEUploidy Workshop.

Haas, M; Tybulewicz, VLJ; Fisher, EMC; Guillemot, F; Cortical development in the Tc1 mouse: a model of Down Syndrome. In: (Proceedings) ANS/AuPS Annual Meeting Sydney 2010.

Haas, M; Tybulewicz, VLJ; Fisher, EMC; Guillemot, F; Cortical neurogenesis in the Tc1 mouse model of Down syndrome. In: (Proceedings) Cortical Development.

Haas, M; Watson-Scales, S; Slender, A; Fisher, EMC; Tybulewicz, V; Guillemot, F; (2012) Understanding Down syndrome using the Tc1 mouse model. In: (Proceedings) Australian Neuroscience Society.

Haas, MA; Fisher, EMC; Tybulewicz, VLJ; Guillemot, F; (2010) Cortical projection neuron dendrite morphology in the Tc1 mouse model of Down Syndrome. In: INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. (pp. 706 - 706). PERGAMON-ELSEVIER SCIENCE LTD

Hafeparast, M; Nicholson, SJ; Witherden, AS; Bermingham, N; Ball, S; Peters, J; ... Fisher, EMC; + view all Loa (Legs at odd angles) a mouse model of motor neurone dysfuntion: mapping and progress towards isolation of the causal gene. In: (Proceedings) 14th International Mammalian Genome Society.

Hafezparast, M; Ahmad-Annuar, A; Lalli, G; Shima, DT; Schiavo, G; Ball, S; ... Ruhrberg, C; + view all Legs at odd angles - a mutation in dynein that impairs the navigation of motor neurons. In: (Proceedings) Molecular Motors 61st Harden Conference.

Hafezparast, M; Ahmad-Annuar, A; Shah, P; Martin, JE; Fisher, EMC; Analysis of the cytoplasmic dynein heavy chain gene, which is mutated in the Loa mouse model of anterior horn cell degeneration. In: Amyotroph. Lateral Scler Other Motor Neuron Disord. (pp. 5 - 227).

Hafezparast, M; Ahmad-Annuar, A; Shah, P; Witherden, AS; Bowen, S; Ball, S; ... Fisher, EMC; + view all Physical and genetic mapping of Loa: a gene involved in motor neuron degeneration. In: (Proceedings) 16th International Mouse Genome Conference.

Hafezparast, M; Ahmad-Annuar, A; Witherden, A; Martin, JEM; Fisher, EMC; What have we learnt from Legs at odd angles - a mouse model of motor neuron degeneration? In: (Proceedings) 12th International symposium on ALS/MND.

Hafezparast, M; Hummerich, H; Fisher, EMC; Isolation of the legs at odd angles (Loa) gene in a nutant mouse with motor neuron degeneration. In: (Proceedings) UK Mouse genome sequencing meeting.

Hafezparast, M; Kieran, D; Bohnert, S; Dick, J; Martin, JE; Fisher, EMC; ... Greensmith, L; + view all Neurodegeneration as a result of defective retrograde axonal transport. In: (Proceedings) Molecular aspects of ageing, and development, toxicology and neuro-immune communication.

Hafezparast, M; Nicholson, SJ; Witherden, AS; Bermingham, N; Ball, S; Peters, J; ... Fisher, EMC; + view all Loa (Legs at odd angles) a mouse model of motor neurone dysfunction: mapping and progress towrds isolation of the causal gene. In: (Proceedings) 2nd Annual Meeting of the International Behavioural and Neural Genetics Society.

Hafezparast, M; Ruhrberg, C; Ahmad-Annuar, A; Bowen, S; Achilli, F; Lalli, G; ... Fisher, EMC; + view all Mutations in dynein link motor neuron degeneration to defects in retrograde transport. In: (Proceedings) 17th International Mouse Genome Conference.

Hafezparast, M; Ruhrberg, C; Ahmad-Annuar, A; Bowen, S; Lalli, G; Preistley, JV; ... Fisher, EMC; + view all Mutations in dynein link motor neuron degeneration to defects in retrograde transport. In: (Proceedings) Molecular Aspects of Neurodegenerative Diseases, Intra-neuronal transport and communication, Euro Conference Series, 2nd Meeting.

Hafezparast, M; Witherden, AS; Nicholson, SJ; Ahmad-Annuar, A; Bermingham, N; Arac, D; ... Fisher, EMC; + view all A transcription map of distal chromosome 12 encompassing Loa: a gene involved in motor neuron degeneration. In: (Proceedings) 4th workshop on Mouse Molecular Neurogenetics.

Hatcher, JP; Rogers, DC; Nolan, P; Fisher, EMC; Martin, JE; Hunter, AJ; Development of SHIRPA to characterise the behavioural phenotype of transgenic and gene-targeted mice. In: (Proceedings) Behavioural phenotyping of mouse mutants.

Hernandez, D; Fisher, EMC; Tybulewicz, V; Modelling Down syndrome. In: (Proceedings) Mouse Molecular Genetics meeting.

Hernandez, D; Mee, P; Martin, J; Tybulewicz, V; Fisher, EMC; Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21. In: (Proceedings) Genetical Society Meeting.

Hernandez, D; Mee, P; Martin, J; Tybulewicz, V; Fisher, EMC; Transchromosomal mouse embyronic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21. In: (Proceedings) HUGO meeting.

Hernandez, D; Tybulewicz, V; Fisher, EMC; (1997) Modelling aspects of Down syndrome in mice. In: CYTOGENET CELL GENET. (pp. 29 - 29). KARGER

Hernandez, D; Tybulewicz, V; Fisher, EMC; (1994) Modelling Down syndrome in mouse. In: Genetics Research (Camb).

Hernandez, D; Tybulewicz, V; Fisher, EMC; Creating as panel of 'transgenomic' mouse embryonic stem cell lines that contain freely segregating portions of human chromosome 21. In: (Proceedings) Gordon Research Conference on Human Molecular Genetics.

Hernandez, D; Tybulewicz, V; Fisher, EMC; Modelling aspects of Down syndrome in mice. In: (Proceedings) International Conference on Down Syndrome and Chromosome 21.

Hernandez, D; Tybulewicz, V; Fisher, EMC; Modelling down syndrome in mice. In: (Proceedings) 3rd International Workshop on The Genetic Control of Vertebrate Development.

Hernandez, D; Tybulewicz, V; Fisher, EMC; Transgenic mouse model for Down syndrome. In: (Proceedings) Models for Development, Developmental Pathology Society Meeting.

Hernandez, D; Tybulewicz, VLJ; Fisher, EMC; Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21. In: (Proceedings) Mouse Molecular Genetics Meeting.

Hernandez, D; Tybulwicz, VLJ; Fisher, EMC; Creating as panel of 'transgenomic' mouse embryonic stem cell lines that contain freely segregating portions of human chromosome 21. In: (Proceedings) International Chromosome 21 Workshop.

Holm, IE; Englund, E; The-FReJA-Consortium,; Ubiquitin positive inclusions in Frontotemporal Dementia linked to chromosome 3 (FTD-3). In: (Proceedings) 16th International Congress on Neuropathology.

Holm, IE; Englund, E; The-FReJA-Consortium,; Ubiquitin positive inclusions in Frontotemporal Dementia linked to chromosome 3 (FTD-3). In: (Proceedings) 5th International Conference on Frontotemporal Dementia.

Holmes, H; Powell, N; Well, J; O'Callaghan, J; Colgan, N; Siow, B; ... Lythgoe, M; + view all (2013) Tensor-based morphometry as a sensitive biomarker of Alzheimer’s disease neuropathology in a Tau transgenic mouse (Tg4510). In: (Proceedings) International Society for Magnetic Resonance in Medicine.

Holmes, H; Wells, J; O'Callaghan, J; Richardson, S; Siow, B; Powell, N; ... Lythgoe, M; + view all (2012) Morphometric genomics: in vivo midro MRI for 3D structural imaging of transgenic mice. In: (Proceedings) International Society for Magnetic Resonance in Medicine British Chapter.

Holmes, H; Wells, J; O'Callaghan, J; Richardson, S; Siow, B; Powell, N; ... Lythgoe, M; + view all (2013) Morphometric Genomics: in vivo microMRI for 3D structural imaging of transgenic mice. In: (Proceedings) International Society for Magnetic Resonance in Medicine.

Holmes, H; Wells, J; Siow, B; O'Callaghan, J; Richardson, S; Oursellin, S; ... Lythgoe, MF; + view all Optimisation of the inv vivo sequence for structural imaging of a mouse model of Alsheimer disease. In: (Proceedings) The International Society for Magnetic Resonance in Medicine.

Hough, T; Fisher, E; Cheeseman, M; Hunter, J; Brown, SDM; (2004) Characterization and genetics of a mouse model of hypophosphatasia. In: GENETICAL RESEARCH. (pp. 120 - 121). CAMBRIDGE UNIV PRESS

Hough, T; Fisher, EMC; Cheeseman, M; Hunter, AJ; Brown, SDM; Characterisation of mouse lines with abnormal levels of plasma alkaline phosphatase. In: (Proceedings) MRC Mammalian Genetics Unit Retreat.

Hough, T; Gray, IC; Nolan, PM; Peters, J; Fisher, EMC; Martin, J; ... Rastan, S; + view all Towards a mutant map of the mouse - new mutant models for bone, renal failure and blood lipids. In: (Proceedings) Mutagenesis Meeting.

Hough, T; Hunter, AJ; Nolan, PM; Tsipouri, V; Goldsworthy, M; Moir, L; ... Brown, SDM; + view all Novel phenotypes identified by plasma biochemical screening in the mouse. In: (Proceedings) 15th International Mouse Genome conference.

Hough, T; Nolan, P; Tsipouri, V; Toye, A; Goldsworthy, M; Moir, L; ... Brown, SDM; + view all Mouse models of human metabolic disorders - characterisation of mutant lines with abnormal levels of plasma alkaline phosphatase. In: (Proceedings) 16th International Mouse Genome Conference.

Hough, T; Nolan, PM; Peters, J; Fisher, EMC; Martin, J; Browne, M; ... Hunter, AJ; + view all Clinical biochemistry screens can complement behavioural screens in mutagenised mice. In: (Proceedings) 2nd Annual Meeting of International Behavioural and Neural Genetics Society.

Hoyle, J; Smith, DJ; Connolly, JAC; Fisher, EMC; (1995) Characterisation of the S4 gene, a member of a highly conserved gene family involved in ubiquitinated degradation of proteins. In: Genetics Research (Camb).

Hoyle, J; Smith, DJ; Fisher, EMC; Characterisation of the S4 gene in mouse and human. In: (Proceedings) 1st conference on the AAA family of ATPases.

Hoyle, J; Smith, DJ; Fisher, EMC; Characterisation of the S4 gene, a member of a highly conserved gene family involved in the ubiquitin protein degradation pathway. In: (Proceedings) Developmental Biology - Gordon Research Conference.

Hoyle, J; Wilkinson, D; Fisher, EMC; Expression of the mouse P26S4 gene, an ATPase regulatory subunit of the 26S proteosome. In: (Proceedings) Gordon Research Conference: Molecular Genetics.

Hunter, AJ; Hagan, JJ; Rogers, D; Nolan, P; Strivens, M; Peters, J; ... Martin, JE; + view all A comprehensive ENU mutagenesis programme has produced novel neurological and behavioural phenotypes. In: (Proceedings) 29th Annual Meeting of the Society for Neurosciences Meeting.

Hunter, AJ; Hagan, JJ; Rogers, D; Nolan, P; Strivens, M; Peters, J; ... Fisher, EMC; + view all A comprehensive ENU mutagenesis programme has produced novel neurological and behavioural phenotypes. In: (Proceedings) 27th Meeting of the European Teratology Society.

Hunter, J; Rogers, D; Hagan, J; Peters, J; Nolan, P; Vizor, L; ... Brown, S; + view all A comprehensive ENU mutagenesis programme for the mouse genome. In: (Proceedings) Physiological Society Meeting, Smithkline Beecham.

Isaacs, AM; Johannsen, P; Nielsen, JE; Holm, I; Fisher, E; Rossor, M; ... Collinge, J; + view all (2011) Frontotemporal dementia caused by CHMP2B mutations. In: Current Alzheimer Research. (pp. 246 - 251).

Isaacs, AM; Skibinski, G; Parkinson, NJ; Brown, JM; Nielsen, JE; Thusgaard, T; ... FReJA-Consortium,; + view all A mutation in CHMP2B is the likely cause of frontotemporal dementia in a large Danish kindred. In: (Proceedings) Society for Neuroscience Meeting.

Isaacs, AM; Skibinski, G; Parkinson, NJ; Brown, JM; Nielsen, JE; Thusgaard, T; ... The-FReJA-Consortium,; + view all A mutation in the endosomal gene CHMP2B in frontotemporal dementia. In: (Proceedings) Society for Neuroscience.

Isaacs, AM; Skibinski, G; Parkinson, NJ; Brown, JM; Nielsen, JE; Thusgaard, T; ... The-FReJA-Consortium,; + view all Mutations in the endosomal gene CHMP2B in frontotemporal dementia. In: (Proceedings) 5th International Conference on Frontotemporal Dementia.

Isaacs, AM; Skibinski, G; Parkinson, NJ; Brown, JM; Nielsen, JE; Thusgaard, T; ... The-FReJA-Consortium,; + view all Mutations in the endosomal gene cHMP2B in frontotemporal dementia. In: (Proceedings) 5th International Conference on the frontotemporal dementias.

Johannsen, P; Eskildesen, S; Neilsen, J; Fisher, EMC; Zeidler, D; Rodell, A; Ostergaard, L; (2006) Functional and structural imaging in FTD3. In: Alzheimer's & Dementia Journal. (pp. S15 - S15).

Johannsen, P; Eskildsen, SF; Nielsen, J; Fisher, EMC; Zeidler, D; Rodell, A; ... The-FReJA-Consortium,; + view all (2006) Brain cortical thickness in a FTD3 patient and mutation carriers. In: The Alzheimer's Society Journal: Alzheimer's & Dementia. (pp. S15 - S15). Elsevier

Johannsen, P; Fraham-Falkenberg, S; Law, I; Jennum, P; Isaacs, A; Brown, J; ... FreJA collaboration,; + view all Changes in cerebral glucose metabolism in early symptomatic frontotemporal dementia linked to chromosome 3 (FTD-3). In: (Proceedings) European Neurology Conference.

Johannsen, P; Frahm-Falkenberg, S; Law, I; Jennum, P; Isaacs, A; Brown, J; ... FReJA Collaboration,; + view all (2011) CHANGES IN CEREBRAL GLUCOSE METABOLISM IN EARLY SYMPTOMATIC FRONTOTEMPORAL DEMENTIA LINKED TO CHROMOSOME 3 (FTD-3). In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 75 - 75). WILEY-BLACKWELL

Johannsen, P; Gade, A; Brown, J; Chakrabarti, L; Ghedde, A; Gydesen, S; ... The-FReJA-Group,; + view all (2002) Extensive cerebral blood flow deficits in chromosome 3 frontotemporal dementia. In: Neurobiology of Ageing. (pp. S59 - S60).

Johannsen, P; Gade, A; Brown, J; Ghakrabarti, K; Gjedde, A; Gydesen, S; ... PET-Centre-and-Dementia-Clinic, A-U-H-A-O-S; + view all Extensive cerebral blood flow deficits in chromosome 2 frontotemporal dementia. In: (Proceedings) 10th International Congress Psychogeriatric Association Meeting.

Johannsen, P; Gade, A; Brown, J; Gydesen, S; Chakrabarti, L; Thusgaard, T; ... Sorensen, SA; + view all Chromosome-3 frontotemporal dementia (FTD3) with global cerebral blood flow decreases. In: (Proceedings) Annual Meeting Danish Neurological Society.

Johannsen, P; Holm, I; Eskildsen, SF; Rodell, A; Isaacs, AM; Gade, A; ... The-FReJA-Consortium,; + view all New imaging and neuropathology findings in FRD-3 patients and mutation carriers. In: (Proceedings) 5th International Conference on Frontotemporal Dementia.

Johannsen, P; Roos, P; Law, I; Frahm-Falkenberg, S; Isaacs, A; Brown, J; Nielsen, JE; (2012) Changes in Cerebral Glucose Metabolism in Early Symptomatic Frontotemporal Dementia Linked to Chromosome 3 (FTD-3). In: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. (pp. 130 - 131).

Johannsen, P; The-FReJA-Consortium,; FTD3 brain imaging. In: (Proceedings) 4th International Conference on Frontotemporal Dementia.

Joyce, P; Fratta, P; Phatac, V; McGoldrick, P; Greensmith, L; Fisher, EMC; Acevedo-Arozena, A; A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: (Proceedings) UK Neuromuscular Translational Research conference.

Joyce, P; Fratta, P; Phatac, V; McGoldrick, P; Greensmith, L; Fisher, EMC; Acevedo-Arozena, A; A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: (Proceedings) UK Neuromuscular Translational Research conference.

Joyce, P; Fratta, P; Phatak, V; McGoldrick, P; Greensmith, L; Fisher, EMC; Acevedo-Arozena, A; A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: (Proceedings) American Society of Neuroscience Annual meeting.

Joyce, P; Fratta, P; Phatak, V; McGoldrick, R; Greensmith, L; Fisher, EMC; Acevedo-Arozena, A; (2011) A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: NEUROMUSCULAR DISORDERS. (pp. S6 - S6). PERGAMON-ELSEVIER SCIENCE LTD

Katsanis, N; Fisher, EMC; Adding to the transcription map of HSA21. In: (Proceedings) 7th International Chromosome 21 Workshop.

Katsanis, N; Fisher, EMC; Identification and mapping single copy expressed sequences on human chromosome 21. In: (Proceedings) 6th International Workshop on Human Chromosome 21.

Katsanis, N; Humphreys, C; Sarner, S; de-Belleroche, J; Collinge, J; Fisher, EMC; An improved protocol for the analysis of Sod1 gene mutations: screening of UK ALS families. In: (Proceedings) 5th International Symposium on ALS and other MND.

Katsanis, N; Yaspo, ML; Fisher, EMC; (1995) cDNA selection from human chromosome 21. In: Genetics Research (Camb).

Katsanis, N; Yaspo, ML; Fisher, EMC; Enrichment of the expressed sequence map of human chromosome 21. In: European Journal of Human Genetics.

Katsanis, N; Yulug, I; Yaspo, ML; Fisher, EMC; Analysis of expressed sequences from human chromosome 21. In: (Proceedings) Gordon Research Conference on Human Molecular Genetics.

Katsanis, N; Yulug, IG; Yaspo, ML; Hernandez, D; Fisher, EMC; cDNA selection and isolation from human chromosome 21. In: (Proceedings) 5th International Workshop on Human Chromosome 21.

Kieran, D; Hafezparast, M; Bohnert, S; Dick, J; Martin, J; Schiavo, G; ... Greensmith, L; + view all A mutation in dynein rescules defects in retrograde axonal transport and delays disease progression in SOD1G93A mice. In: (Proceedings) Society for Neuroscience Annual Meeting.

Kieran, D; Hafezparast, M; Bohnert, S; Dick, J; Martin, J; Schiavo, G; ... Greensmith, L; + view all Disrupted axonal transport in SOD1G93A transgenics is restored by mutant dynein, so significantly extending lifespan. In: (Proceedings) 15th International ALS symposium.

Kieran, D; Hafezparast, M; Bohnert, S; Dick, JRT; Martin, J; Schiavo, G; ... Greensmith, L; + view all A point mutation in dynein delays disease progression in SOD1G93A mice, a model of amyotrophic lateral sclerosis. In: (Proceedings) 5th Jackson Lab Neurogenetics Conference.

Kieran, D; Hafezparast, M; Martin, JE; Fisher, EMC; Greensmith, L; (2003) Delaying disease progression in mSOD transgenic mice. In: Amyotroph. Lateral Scler Other Motor Neuron Disord. (pp. 5 - 227).

Knapp, S; Hosie, AM; Anstee, QM; Thomos, P; Mortensen, M; Martinez, A; ... Thomas, HC; + view all (2008) IDENTIFICATION OF A MODEL OF ALCOHOL PREFERENCE AND ITS SIMILARITY TO HUMAN ALCOHOLISM. In: HEPATOLOGY. (pp. 398A - 399A). JOHN WILEY & SONS INC

Knapp, S; Hosie, AM; Thomas, P; Martinez, A; Mortensen, M; Brown, SDM; ... Thomas, HC; + view all Mutation of the GABA a receptor b1 gene with ENU results in alcohol preference in mice. In: (Proceedings) European Society for Biomedical Research in Alcoholism.

Kuta, A; Banks, G; Parkinson, N; Quwailid, MM; Fisher, EMC; Screening for dynein complex mutations in an ENU mouse library. In: (Proceedings) International Mammalian Genome Conference.

Lana-Elola, E; Watson-Scales, S; Slender, A; Dunlevy, L; Bennett, M; Mohun, T; ... Tybulewicz, V; + view all Engineering new mouse models to map dosage-sensitive genes in Down syndrome congenital heart defects. In: (Proceedings) Weinstein Cardiovascular Conference.

Levey, PM; Bermingham, NA; Fisher, EMC; Martin, JE; Expression of lysosomal membrane glycoproteins LAMP-1 and LAMP-2 in the central nervous system. In: (Proceedings) Neuropathological Society.

Levey, PM; Bermingham, NA; Fisher, EMC; Martin, JE; Expression of lysosomal membrane glycoproteins LAMP-1 and LAMP-2 in the central nervouse system. In: Neuropathology and Applied Neurobiology.

Line, SJ; Papaioannou, D; Fisher, EMC; Tybulewicz, VJL; Bannerman, DM; Deacon, R; An aneuploid mouse which models Down syndrome displays deficits in spatial working memory and motor coordination. In: (Proceedings) Firt AnEUploidy Workshop.

Lloyd, S; Onwuazor, O; Uphill, J; Beck, J; Farrall, M; Targonski, P; ... Fisher, EMC; + view all Identification of multiple quantitative trait loci linked to prion disease incubation time. In: (Proceedings) 15th International Mouse Genome Conference.

Lloyd, SE; Beck, JA; Fisher, EMC; Collinge, J; Quantative trait locus analysis of prion disease incubation time. In: (Proceedings) 13th International Mouse Genome Conference.

Lloyd, SE; Maytham, ELG; Thompson, S; Mott, R; Fisher, EMC; Collinge, J; Fine mapping prion disease incubation time QTL using heterogeneous stock mice. In: (Proceedings) 18th International Mouse Genome Conference.

Lloyd, SE; Thompson, S; Mott, R; Collinge, J; Fisher, EMC; Quantitative trait locus analysis of prion disease incubation time in mice. In: (Proceedings) 19th International Congress of Genetics.

Lloyd, SE; Thompson, S; Mott, R; Fisher, EMC; Collinge, J; Quantitative trait locus analysis of prion disease incubation time in mice. In: (Proceedings) Complex Trait Consortium meeting.

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