UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Browse by UCL people

Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Group by: Type | Date
Number of items: 612.

Article

Acevedo-Arozena, A; Kalmar, B; Essa, S; Ricketts, T; Joyce, P; Kent, R; Rowe, C; (2011) A comprehensive assessment of the SOD1(G93A) low-copy transgenic mouse, which models human amyotrophic lateral sclerosis. DIS MODEL MECH , 4 (5) 686 - 700. 10.1242/dmm.007237. Gold open access

Achilli, F; Boyle, S; Kieran, D; Chia, R; Hafezparast, M; Martin, JE; Schiavo, G; (2005) The SOD1 transgene in the G93A mouse model of amyotrophic lateral sclerosis lies on distal mouse chromosome 12. AMYOTROPH LATERAL SC , 6 (2) 111 - 114. 10.1080/14660820510035351.

Achilli, F; Bros-Facer, V; Williams, HP; Banks, GT; AlQatari, M; Chia, R; Tucci, V; (2009) An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. Disease Models & Mechanisms , 2 (7-8) 359 - 373. 10.1242/dmm.002527. Green open access
file

Ahmad-Annuar, A; Shah, P; Hafezparast, M; Hummerich, H; Witherden, AS; Morrison, KE; Shaw, PJ; (2003) No association with common Caucasian genotypes in exons 8, 13 and 14 of the human cytoplasmic dynein heavy chain gene (DNCHC1) and familial motor neuron disorders. AMYOTROPH LATERAL SC , 4 (3) 150 - 157.

Ahmad-Annuar, A; Tabrizi, SJ; Fisher, EMC; (2003) Mouse models as a tool for understanding neurodegenerative diseases. CURR OPIN NEUROL , 16 (4) 451 - 458. 10.1097/01.wco.0000084221.82329.29.

Ahmed, ; Dhanasekaran, ; Tong, ; Wiseman, F; Fisher, EMC; Tybulewicz, V; Gardiner, ; (2013) Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain. Molecular Genetics and Genomics: an international journal

Ahmed, MM; Dhanasekaran, AR; Tong, S; Wiseman, FK; Fisher, EM; Tybulewicz, VL; Gardiner, KJ; (2013) Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain. Human Molecular Genetics , 22 (9) 1709 -1724. 10.1093/hmg/ddt017. Green open access
file

Alford, KA; Slender, A; Vanes, L; Li, Z; Fisher, EMC; Nizetic, D; Orkin, SH; (2010) Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome. BLOOD , 115 (14) 2928 - 2937. 10.1182/blood-2009-06-227629.

Anstee, QM; Knapp, S; Maguire, EP; Hosie, AM; Thomas, P; Mortensen, M; Bhome, R; (2013) Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition. Nat Commun , 4 2816 - ?. 10.1038/ncomms3816.

Ashworth, A; Lloyd, S; Brown, J; Gydesen, S; Sorensen, SA; Brun, A; Englund, E; (1999) Molecular genetic characterisation of frontotemporal dementia on chromosome 3. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS , 10 93 - 101.

Ateh, DD; Hussain, IK; Mustafa, AH; Price, KM; Gulati, R; Nickols, CD; Bird, MM; (2008) Dynein-dynactin complex subunits are differentially localized in brain and spinal cord, with selective involvement in pathological features of neurodegenerative disease. NEUROPATH APPL NEURO , 34 (1) 88 - 94. 10.1111/j.1365-2990.2007.00924.x.

BROCKDORFF, N; FISHER, EMC; CAVANNA, J; LYON, MF; BROWN, SDM; (1987) THE MOLECULAR MAPPING OF THE MOUSE X-CHROMOSOME. GENET RES , 49 (3) 258 - 258.

BROCKDORFF, N; FISHER, EMC; CAVANNA, JS; LYON, MF; BROWN, SDM; (1987) CONSTRUCTION OF A DETAILED MOLECULAR MAP OF THE MOUSE X-CHROMOSOME BY MICROCLONING AND INTERSPECIFIC CROSSES. EMBO J , 6 (11) 3291 - 3297.

BROCKDORFF, N; FISHER, EMC; ORKIN, SH; LYON, MF; BROWN, SDM; (1988) LOCALIZATION OF THE HUMAN X-LINKED GENE FOR CHRONIC GRANULOMATOUS-DISEASE TO THE MOUSE X-CHROMOSOME - IMPLICATIONS FOR X-CHROMOSOME EVOLUTION. CYTOGENET CELL GENET , 48 (2) 124 - 125.

BROWN, SDM; BROCKDORFF, N; CAVANNA, JS; FISHER, EMC; GREENFIELD, AJ; LYON, MF; NASIR, J; (1988) THE LONG-RANGE MAPPING OF MAMMALIAN CHROMOSOMES. CURR TOP MICROBIOL , 137 3 - 12.

Banks, G.T.; Bros-Facer, V.; Williams, H.P.; Chia, R.; Achilli, F.; Bryson, J.B.; Greensmith, L.; (2009) Mutant glycyl-tRNA synthetase (Gars) ameliorates SOD1G93A motor neuron degeneration phenotype but has little affect on Loa dynein heavy chain mutant mice. PLoS ONE , 4 (7) , Article e6218. 10.1371/journal.pone.0006218. Green open access
file

Banks, GT; Bros-Facer, V; Williams, HP; Chia, R; Achilli, F; Bryson, JB; Greensmith, L; (2009) Mutant Glycyl-tRNA Synthetase (Gars) Ameliorates SOD1(G93A) Motor Neuron Degeneration Phenotype but Has Little Affect on Loa Dynein Heavy Chain Mutant Mice. PLOS ONE , 4 (7) , Article e6218. 10.1371/journal.pone.0006218. Green open access
file

Banks, GT; Fisher, EMC; (2008) Cytoplasmic dynein could be key to understanding neurodegeneration. GENOME BIOL , 9 (3) , Article 214. 10.1186/gb-2008-9-3-214. Gold open access

Banks, GT; Haas, MA; Line, S; Shepherd, HL; AlQatari, M; Stewart, S; Rishal, I; (2011) Behavioral and Other Phenotypes in a Cytoplasmic Dynein Light Intermediate Chain 1 Mutant Mouse. J NEUROSCI , 31 (14) 5483 - 5494. 10.1523/JNEUROSCI.5244-10.2011. Gold open access

Banks, GT; Kuta, A; Isaacs, AM; Fisher, EMC; (2008) TDP-43 is a culprit in human neurodegeneration, and not just an innocent bystander. MAMM GENOME , 19 (5) 299 - 305. 10.1007/s00335-008-9117-x. Gold open access

Beck, JA; Lloyd, S; Hafezparast, M; Lennon-Pierce, M; Eppig, JT; Festing, MFW; Fisher, EMC; (2000) Genealogies of mouse inbred strains. NAT GENET , 24 (1) 23 - +.

Becker, EBE; Olivera, PL; Glitsch, MD; Banks, GT; Achilli, F; Hardy, A; Nolan, PM; (2009) A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice. P NATL ACAD SCI USA , 106 (16) 6706 - 6711. 10.1073/pnas.0810599106.

Bermingham, N; Gilmour, F; Martin, JE; Fisher, EMC; (1995) Human glial cell line-derived neurotrophic factor (GDNF) maps to chromosome 5. Hum Genet , 96 671 - 673.

Bermingham, N; Hernandez, D; Balfour, A; Gilmour, F; Martin, JE; Fisher, EMC; (1995) Mapping TNNC1, the gene which encodes cardiac troponin I in the human and the mouse. Genomics , 30 620 - 622.

Bermingham, N; Martin, JE; Fisher, EMC; (1996) The mouse lysosomal membrane protein 1 gene as a candidate for the motorneuron degeneration (mnd) locus. Genomics , 32 266 - 271.

Bermingham, N; McKay, T; Hoyle, J; Hernandez, D; Martin, JE; Fisher, EMC; (1996) The gene encoding tripeptidyl peptidase II maps to chromosome 1 in the mouse. Mamm Genome , 7 390 - ?.

Bermingham, NA; Rauf, S; Katsanis, N; Martin, JE; Hunter, AJ; Fisher, EMC; (1998) The immunophilin FKBP4 (FKBP52/FKBP59) maps to the distal short arm of human chromosome 12. Mamm Genome , 9 268 - ?.

Bowen, S; Ateh, DD; Deinhardt, K; Bird, MM; Price, KM; Baker, CS; Robson, JC; (2007) The phagocytic capacity of neurones. EUR J NEUROSCI , 25 (10) 2947 - 2955. 10.1111/j.1460-9568.2007.05554.x.

Brockdorff, N; Cross, GS; Cavanna, JS; Fisher, EMC; Lyon, MF; Davies, KE; Brown, SDM; (1987) The mapping of a cDNA from the human X linked Duchenne muscular dystrophy gene to the mouse X chromosome. Nature , 328 166 - 168.

Brown, J; Gydesen, S; Johannsen, P; Gade, A; Skibinski, G; Chakrabarti, L; Brun, A; (2004) Frontotemporal dementia linked to chromosome 3. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS , 17 (4) 274 - 276. 10.1159/000077153.

Bunton-Stasyshyn, RK; Saccon, RA; Fratta, P; Fisher, EM; (2014) SOD1 Function and Its Implications for Amyotrophic Lateral Sclerosis Pathology: New and Renascent Themes. Neuroscientist 10.1177/1073858414561795. (In press). Green open access
file

Canzonetta, C; Mulligan, C; Deutsch, S; Ruf, S; O'Doherty, A; Lyle, R; Borel, C; (2008) DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome. AM J HUM GENET , 83 (3) 388 - 400. 10.1016/j.ajhg.2008.08.012.

Chakrabarti, L; FReJA, ; (2001) Clinical and molecular characterisation of frontotemporal dementia linked to human chromosome 3. AMERICAN JOURNAL OF HUMAN GENETICS , 69 (4) 278 - 278.

Chia, R; Achilli, F; Festing, MFW; Fisher, EMC; (2005) The origins and uses of mouse outbred stocks. NAT GENET , 37 (11) 1181 - 1186. 10.1038/ng1665.

Chia, R; Tattum, MH; Jones, S; Collinge, J; Fisher, EMC; Jackson, GS; (2010) Superoxide Dismutase 1 and tgSOD1(G93A) Mouse Spinal Cord Seed Fibrils, Suggesting a Propagative Cell Death Mechanism in Amyotrophic Lateral Sclerosis. PLOS ONE , 5 (5) , Article e10627. 10.1371/journal.pone.0010627. Green open access
file

Chio, A; Schymick, JC; Restagno, G; Scholz, SW; Lombardo, F; Lai, SL; Mora, G; (2009) A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. HUM MOL GENET , 18 (8) 1524 - 1532. 10.1093/hmg/ddp059.

Cleary, JO; Wiseman, FK; Norris, FC; Price, AN; Choy, M; Tybulewicz, VLJ; Ordidge, RJ; (2011) Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain. NEUROIMAGE , 56 (3) 974 - 983. 10.1016/j.neuroimage.2011.01.082.

Cole, SE; Wiltshire, T; Rue, EE; Morrow, D; Hieter, P; Brahe, C; Fisher, EMC; (1999) High-resolution comparative physical mapping of mouse Chromosome 10 in the region of homology with human Chromosome 21. Mammalian Genome , 10 (3) 229 - 234.

Cortese, A; Plagnol, V; Brady, S; Simone, R; Lashley, T; Acevedo-Arozena, A; de Silva, R; (2014) Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy. Neurobiology of Aging , 35 (6) pp. 1491-1498. 10.1016/j.neurobiolaging.2013.12.029. Green open access
file

Curtin, JA; Quint, E; Tsipouri, V; Arkell, RM; Cattanach, B; Copp, AJ; Henderson, DJ; (2003) Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. CURR BIOL , 12 (13) 1129 - 1133. 10.1016/S0960-9822(03)00374-9.

De Vita, S; Canzonetta, C; Mulligan, C; Delom, F; Groet, J; Baldo, C; Vanes, L; (2010) Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome. ONCOGENE , 29 (46) 6102 - 6114. 10.1038/onc.2010.351.

Deng, W; Garrett, C; Dombert, B; Soura, V; Banks, G; Fisher, EMC; van der Brug, MP; (2011) Neurodegenerative mutation in cytoplasmic dynein alters its organization and dynein-dynactin and dynein-kinesin interactions. J Biol Chem , 285 (51) 39922 - 39932.

Devoy, A; Bunton-Stasyshyn, RK; Tybulewicz, VL; Smith, AJ; Fisher, EM; (2012) Genomically humanized mice: technologies and promises. Nat Rev Genet , 13 (1) 14 - 20. 10.1038/nrg3116.

Doherty, AMO; Fisher, EMC; (2003) Microcell-mediated chromosome transfer (MMCT): small cells with huge potential. MAMM GENOME , 14 (9) 583 - 592. 10.1007/s00335-003-4002-0.

Duchon, A; Pothion, S; Brault, V; Sharp, AJ; Tybulewicz, VLJ; Fisher, EMC; Herault, Y; (2011) The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome. BEHAV BRAIN RES , 217 (2) 271 - 281. 10.1016/j.bbr.2010.10.023.

Dunlevy, L; Bennett, M; Slender, A; Lana-Elola, E; Tybulewicz, VL; Fisher, EMC; Mohun, T; (2010) Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse. CARDIOVASC RES , 88 (2) 287 - 295. 10.1093/cvr/cvq193.

El-Kadi, AM; Bros-Facer, V; Deng, WH; Philpott, A; Stoddart, E; Banks, G; Jackson, GS; (2010) The Legs at odd angles (Loa) Mutation in Cytoplasmic Dynein Ameliorates Mitochondrial Function in SOD1(G93A) Mouse Model for Motor Neuron Disease. J BIOL CHEM , 285 (24) 18627 - 18639. 10.1074/jbc.M110.129320. Gold open access

FISHER, EMC; CAVANNA, JS; BROCKDORFF, N; LYON, MF; BROWN, SDM; (1986) THE MOLECULAR MAPPING OF THE MOUSE X-CHROMOSOME. HEREDITY , 57 286 - 286.

Festing, MFW; Fisher, EMC; (2000) Mighty mice - Clarence Little's brainwave gave biomedical researchers their best friend. NATURE , 404 (6780) 815 - 815.

Filimonenko, M; Stuffers, S; Raiborg, C; Yamamoto, A; Malerod, L; Fisher, EMC; Isaacs, A; (2007) Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. J CELL BIOL , 179 (3) 485 - 500.

Fisher, EMC; (2003) The mouse: genetics and genome. Genetics Society Newsletter , 50 7 - 9.

Fisher, EMC; (1998) Modelling motor neuron degenerative disease. Neuropathol. Appl. Neurobiol. , 24 90 - ?.

Fisher, EMC; (1997) The contribution of the mouse to advances in human genetics. Advances in Genetics , 35 155 - 205. 10.1016/S0065-2660(08)60450-2.

Fisher, EMC; (1995) Why aren't we all bacteria. Immunology News , 2 100 - 103.

Fisher, EMC; (1993) Much ado about cloning. BMJ , 307 (6911) 1074 - 1075.

Fisher, EMC; (1993) Working with the media. Physiological Society Magazine , 8 25 - 25.

Fisher, EMC; (1991) On air. Science and Public Affairs , 1 5 - 6.

Fisher, EMC; Alitalo, T; Luoh, SW; de-la-Chapelle, A; Page, DC; (1990) Human sex-chromosome-specific repeats within a region of pseudoautosomal/Yq homology. Genomics , 7 625 - 628.

Fisher, EMC; Beer-Romero, P; Brown, LG; Ridley, A; McNeil, JA; Bentley-Lawrence, J; Willard, HF; (1990) Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome. Cell , 63 1205 - 1218.

Fisher, EMC; Cavanna, JS; Brown, SDM; (1985) Microdissection and microcloning of the mouse X chromosome. Proc. Natl. Acad. Sci. , 82 5846 - 5849.

Fisher, EMC; Lana-Elola, E; Watson, SD; Vassiliou, G; Tybulewicz, VLJ; (2009) New approaches for modelling sporadic genetic disease in the mouse. DIS MODEL MECH , 2 (9-10) 446 - 453. 10.1242/dmm.001644. Gold open access

Fisher, EMC; Scambler, PJ; (1994) Human haploinsufficiency - one for sorrow, two for joy. Nature Genetics , 7 5 - 7.

Fisher, EMC; Telling, G; Collinge, J; (1998) Prions and the prion disorders. Mamm Genome , 9 (7) 497 - 502.

Fisher, EMC; Tybulewicz, VLJ; (2006) Understanding Down Syndrome. Science and Public Affairs , 9

Fratta, P; Charnock, J; Collins, T; Devoy, A; Howard, R; Malaspina, A; Orrell, R; (2013) Profilin1 E117G is a moderate risk factor for amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry , 85 pp. 506-508. 10.1136/jnnp-2013-306761. Green open access
file

Fratta, P; Collins, T; Pemble, S; Nethisinghe, S; Devoy, A; Giunti, P; Sweeney, MG; (2014) Sequencing analysis of the spinal bulbar muscular atrophy CAG expansion reveals absence of repeat interruptions. Neurobiol Aging , 35 (2) 443.e1 - 443.e3. 10.1016/j.neurobiolaging.2013.07.015.

Fratta, P; Hanna, MG; Fisher, EM; Sidle, K; (2013) An unusual presentation for SOD1-ALS: Isolated facial diplegia. Muscle Nerve , 48 (6) pp. 994-995. 10.1002/mus.23958. Green open access
file

Fratta, P; Malik, B; Gray, A; La Spada, AR; Hanna, MG; Fisher, EM; Greensmith, L; (2013) FUS is not dysregulated by the spinal bulbar muscular atrophy androgen receptor polyglutamine repeat expansion. Neurobiology of Aging , 34 (5) 1516.e17 - 1516.e19. 10.1016/j.neurobiolaging.2012.09.008. Green open access
file

Fratta, P; Mizielinska, S; Nicoll, AJ; Zloh, M; Fisher, EM; Parkinson, G; Isaacs, AM; (2012) C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes. Scientific Reports , 2 , Article 1016. 10.1038/srep01016. Green open access
filefilefilefilefilefile

Fratta, P; Nirmalananthan, N; Masset, L; Skorupinska, I; Collins, T; Cortese, A; Pemble, S; (2014) Correlation of clinical and molecular features in spinal bulbar muscular atrophy. Neurology , 82 (23) pp. 2077-2084. 10.1212/WNL.0000000000000507. Green open access
file

Fratta, P; Polke, JM; Newcombe, J; Mizielinska, S; Lashley, T; Poulter, M; Beck, J; (2015) Screening a UK amyotrophic lateral sclerosis cohort provides evidence of multiple origins of the C9orf72 expansion. Neurobiol Aging , 36 (1) 546.e1 - 546.e7. 10.1016/j.neurobiolaging.2014.07.037.

Fratta, P; Poulter, M; Lashley, T; Rohrer, JD; Polke, JM; Beck, J; Ryan, N; (2013) Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia. Acta Neuropathologica , 126 (3) pp. 401-409. 10.1007/s00401-013-1147-0. Green open access
filefilefile

Galante, M; Jani, H; Vanes, L; Daniel, H; Fisher, EMC; Tybulewicz, VLJ; Bliss, TVP; (2009) Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome. HUM MOL GENET , 18 (8) 1449 - 1463. 10.1093/hmg/ddp055.

Galante, M.; Jani, H.; Vanes, L.; Daniel, H.; Fisher, E.M.C.; Tybulewicz, V.L.J.; Bliss, T.V.P.; (2009) Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome. Human Molecular Genetics , 18 (8) pp. 1449-1463. 10.1093/hmg/ddp055. Green open access
file

Garrett, CA; Barri, M; Kuta, A; Soura, V; Deng, W; Fisher, EM; Schiavo, G; (2014) DYNC1H1 mutation alters transport kinetics and ERK1/2-cFos signalling in a mouse model of distal spinal muscular atrophy. Brain , 137 (Pt 7) 1883 - 1893. 10.1093/brain/awu097.

Ghazi-Noori, S; Froud, KE; Mizielinska, S; Powell, C; Smidak, M; Fernandez de Marco, M; O'Malley, C; (2012) Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice. Brain , 135 (Pt 3) 819 - 832. 10.1093/brain/aws006.

Gribble, SM; Wiseman, FK; Clayton, S; Prigmore, E; Langley, E; Yang, F; Maguire, S; (2013) Massively Parallel Sequencing Reveals the Complex Structure of an Irradiated Human Chromosome on a Mouse Background in the Tc1 Model of Down Syndrome. PLOS ONE , 8 (4) , Article e60482. 10.1371/journal.pone.0060482. Green open access
file

Grizenkova, J; Akhtar, S; Hummerich, H; Tomlinson, A; Asante, EA; Wenborn, A; Fizet, J; (2012) Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice. Proc Natl Acad Sci U S A , 109 (34) 13722 - 13727. 10.1073/pnas.1208917109. Gold open access

Gydesen, S; Brown, JM; Brun, A; Chakrabarti, L; Gade, A; Johannsen, P; Rossor, M; (2004) Chromosome 3 linked frontotemporal dementia (FTD-3). Dementia Review (1/2004)

Gydesen, S; Brown, JM; Brun, A; Chakrabarti, L; Gade, A; Johannsen, P; Rossor, M; (2002) Chromosome 3 linked frontotemporal dementia (FTD-3). NEUROLOGY , 59 (10) 1585 - 1594.

Haas, MA; Bell, D; Slender, A; Lana-Elola, E; Watson-Scales, S; Fisher, EMC; Tybulewicz, VLJ; (2013) Alterations to Dendritic Spine Morphology, but Not Dendrite Patterning, of Cortical Projection Neurons in Tc1 and Ts1Rhr Mouse Models of Down Syndrome. Plos One , 8 (10) , Article e78561. 10.1371/journal.pone.0078561. Green open access
filefilefilefilefilefile

Hafezparast, M; Ahmad-Annuar, A; Hummerich, H; Shah, P; Ford, M; Baker, C; Bowen, S; (2003) Paradigms for the identification of new genes in motor neuron degeneration. AMYOTROPH LATERAL SC , 4 (4) 249 - 257. 10.1080/14660820310016084.

Hafezparast, M; Ahmad-Annuar, A; Wood, NW; Tabrizi, SJ; Fisher, EMC; (2003) Mouse models for neurological disease. Adv Clin Neurosci , 13 305 - ?.

Hafezparast, M; Ahmad-Annuar, A; Wood, NW; Tabrizi, SJ; Fisher, EMC; (2002) Mouse models for neurological disease. LANCET NEUROL , 1 (4) 215 - 224.

Hafezparast, M; Ball, S; Nicholson, SJ; Witherden, A; Arac, D; Broadway, N; Saggerson, D; (2002) A new mouse mutant, skijumper. MAMM GENOME , 13 (7) 359 - 364. 10.1007/s003350030008.

Hafezparast, M; Brandner, S; Linehan, J; Martin, JE; Collinge, J; Fisher, EMC; (2005) Prion disease incubation time is not affected in mice heterozygous for a dynein mutation. BIOCHEM BIOPH RES CO , 326 (1) 18 - 22. 10.1016/j.bbrc.2004.10.206.

Hafezparast, M; Fisher, EMC; (1999) Polyglutamine diseases. Trend Genet , 15 222 - ?.

Hafezparast, M; Fisher, EMC; (1998) Wasted by an elongation factor. Trends Genet , 14 215 - 217.

Hafezparast, M; Klocke, R; Ruhrberg, C; Marquardt, A; Ahmad-Annuar, A; Bowen, S; Lalli, G; (2003) Mutations in dynein link motor neuron degeneration to defects in retrograde transport. SCIENCE , 300 (5620) 808 - 812.

Hafezparast, M; Witherden, A; Nicholson, S; Bermingham, N; Mackin, J; ten Asbroek, A; Ball, S; (1999) The kinesin light chain gene: its mapping and exclusion in mouse and human forms of inherited motor neuron degeneration. NEUROSCI LETT , 273 (1) 49 - 52.

Hafezparast, M.; Klocke, R.; Ruhrberg, C.; Marquardt, A.; Ahmad-Annuar, A.; Bowen, S.; Lalli, G.; (2003) Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science , 300 (5620) pp. 808-812. 10.1126/science.1083129.

Hamvas, RMJ; Zinn, A; Keer, JT; Fisher, EMC; Beer-Romero, P; Brown, SDM; Page, D; (1992) Rps4 maps near the inactivation center on the mouse X chromosome. Genomics , 12 363 - 367.

Hernandez, D; Fisher, EMC; (1999) Mouse autosomal trisomy - two’s company, three’s a crowd. Trends in Genetics , 15 241 - 247.

Hernandez, D; Fisher, EMC; (1996) Down syndrome genetics: unravelling a multifactorial disorder. Hum Mol Genet , 5 1411 - 1416.

Hernandez, D; Mee, PJ; Martin, JE; Tybulewicz, VLJ; Fisher, EMC; (1999) Transchromosomal mouse embryonic stem cell lines that contain a freely segregating whole or partial human chromosome 21. Human Molecular Genetics , 8 (5) 923 - 933.

Hernandez, D; Pannett, A; Tybulewicz, V; Fisher, EMC; (1995) Highly polymorphic sequence at D21S1448 mapping close to D21S55. Hum Genet , 95 721 - 722.

Hernandez, D; Yulug, IG; Egan, SE; Fisher, EMC; (1994) Mapping the gene which encodes phosphatidylinositol specific phospholipase C-g 2 in the human and the mouse. Genomics , 23 504 - 507.

Holm, IE; Isaacs, AM; Mackenzie, IRA; FReJA-Consortium, ; (2009) Absence of FUS-immunoreactive pathology in frontotemporal dementia linked to chromosome 3 (FTD-3) caused by mutation in the CHMP2B gene. Acta Neuropathologica , 118 719 - 720.

Holme, IE; Englund, E; Mackenzie, IRA; Johannsen, P; Isaacs, AM; The-FReJA-Consortium, ; (2007) A reassessment of the neuropathology of frontotemporal dementia linked to chromosome 3. J. Neuropathol. Exp. Neurol , 66 884 - 891.

Hough, TA; Nolan, PM; Tsipouri, V; Toye, AA; Gray, IC; Goldsworthy, M; Moir, L; (2002) Novel phenotypes identified by plasma biochemical screening in the mouse. MAMM GENOME , 13 (10) 595 - 602. 10.1007/s00335-002-2188-1.

Hough, TA; Polewski, M; Johnson, K; Cheeseman, M; Nolan, PM; Vizor, L; Rastan, S; (2007) Novel mouse model of autosomal semidominant adult Hypophosphatasia has a splice site mutation in the tissue nonspecific alkaline phosphatase gene Akp2. J BONE MINER RES , 22 (9) 1397 - 1407.

Hoyle, J; Fisher, EMC; (1996) Genomic organization and mapping of the mouse P26s4 ATPase gene: a member of the remarkably conserved AAA gene family. Genomics , 31 115 - 118.

Hoyle, J; Phelan, JP; Bermingham, N; Fisher, EMC; (1996) Localization of human and mouse N-ethylmaleimide-sensitive factor (NSF) gene: a two domain member of the AAA family which is involved in membrane fusion. Mamm Genome , 7 850 - ?.

Hoyle, J; Tan, KH; Fisher, EMC; (1997) Localization of genes encoding two human one domain members of the AAA family: PSMC5 (the thyroid hormone receptor interacting protein, TRIP1) and PSMC3 (the Tat binding protein, TBP1). Hum Genet , 99 285 - 288.

Hoyle, J; Tan, KH; Fisher, EMC; (1997) Mapping human and mouse valosin containing protein (VCP) sequences. Mamm. Genome , 8 778 - 780.

Hoyle, J; Yulug, IG; Egan, SE; Fisher, EMC; (1994) The gene which encodes the phosphatidylinositol-3 kinase regulatory subunit (p85a) maps to chromosome 13 in the mouse. Genomics , 24 400 - 402.

Hoyle, J; Yulug, IG; Johnstone, K; Scambler, PJ; Fisher, EMC; (1996) Characterisation of a short interspersed repeat (Mermaid) which has family members on human chromosome 21 and elsewhere in the human genome. Hum Genet , 97 117 - 120.

Hunter, AJ; Hagan, JJ; Rogers, D; Nolan, P; Strivens, M; Peters, J; Brown, SDM; (2000) The discovery of novel behavioural phenotypes via a genome wide mutagenesis programme. EUR J NEUROSCI , 12 442 - 442.

Ingram, CJ; Weale, ME; Plaster, CA; Morrison, KE; Goodall, EF; Pall, HS; Beck, M; (2012) Analysis of European case-control studies suggests that common inherited variation in mitochondrial DNA is not involved in susceptibility to amyotrophic lateral sclerosis. Amyotroph Lateral Scler , 13 (4) 341 - 346. 10.3109/17482968.2012.654394.

Isaacs, AM; Davies, KE; Hunter, AJ; Nolan, PM; Vizor, L; Peters, J; Gale, DG; (2000) Identification of two new Pmp22 mouse mutants using large-scale mutagenesis and a novel rapid mapping strategy. HUM MOL GENET , 9 (12) 1865 - 1871.

Isaacs, AM; Johannsen, P; Holm, I; Nielsen, JE; FReJA Consortium, ; (2011) Frontotemporal Dementia Caused by CHMP2B Mutations. CURR ALZHEIMER RES , 8 (3) 246 - 251. Gold open access

Johannsen, P; Gydesen, S; Brown, J; Gade, A; Chakrabarti, L; Skibinski, G; Englund, E; (2003) Chromosome 3 related frontotemporal dementia. INT PSYCHOGERIATR , 15 81 - 81.

Joyce, PI; Fratta, P; Fisher, EMC; Acevedo-Arozena, A; (2011) SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments. MAMM GENOME , 22 (7-8) 420 - 448. 10.1007/s00335-011-9339-1.

Joyce, PI; Mcgoldrick, P; Saccon, RA; Weber, W; Fratta, P; West, SJ; Zhu, N; (2015) A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity. Hum Mol Genet , 24 (7) 1883 - 1897. 10.1093/hmg/ddu605.

Kasperaviciute, D; Weale, ME; Shianna, KV; Banks, GT; Simpson, CL; Hansen, VK; Turner, MR; (2007) Large-scale pathways-based association study in amyotrophic lateral sclerosis. BRAIN , 130 2292 - 2301. 10.1093/brain/awm055.

Katsanis, N; Beck, JA; Fisher, EMC; (1997) Mapping of a novel SH3 domain protein and two proteins of unknown function to human chromosome 21. Hum Genet , 100 477 - 480.

Katsanis, N; Fisher, EMC; (1998) Identification, expression and chromosomal localization of ubiquitin conjugating enzyme 7 (UBE2G2), a human homolog of the Saccharomyces cerevisiae Ubc7 gene. Genomics , 51 128 - ?.

Katsanis, N; Fisher, EMC; (1998) A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3. Genomics , 47 294 - 299.

Katsanis, N; Fisher, EMC; (1996) The gene encoding the p60 subunit of chromatin assembly factor I (CAF1P60) maps to human chromosome 21q22.2, a region associated with some of the major features of Down syndrome. Hum Genet , 98 497 - ?.

Katsanis, N; Fitzgibbon, J; Fisher, EMC; (1996) Paralogy mapping: identification of a region in the human MHC triplicated onto human chromosomes 1 and 9 allows the prediction and isolation of novel PBX and NOTCH loci. Genomics , 35 101 - 108.

Katsanis, N; Ives, JH; Groet, J; Nizetic, D; Fisher, EMC; (1998) Localisation of Receptor Interacting Protein 140 (RIP140) within 100kb of D21S13 on 21q11, a gene-poor region of the human genome. Hum Genet , 102 221 - ?.

Katsanis, N; Yaspo, M; Fisher, EMC; (1997) Identification and mapping of a novel human gene, PRMT2, homologous to the rat protein arginine N-methyltransferase 1 (PRMT1) gene. Mamm Genome , 8 526 - 529.

Kieran, D; Hafezparast, M; Bohnert, S; Dick, JRT; Martin, J; Schiavo, G; Fisher, EMC; (2005) A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice. J CELL BIOL , 169 (4) 561 - 567. 10.1083/jcb.200501085.

Kieran, D.; Hafezparast, M.; Bohnert, S.; Dick, J.R.T.; Martin, J.; Schiavo, G.; Fisher, E.M.C.; (2005) A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice. The Journal of Cell Biology , 169 (4) pp. 561-567. 10.1083/jcb.200501085. Green open access
file

Kuta, A; Deng, WH; El-Kadi, AM; Banks, GT; Hafezparast, M; Pfister, KK; Fisher, EMC; (2010) Mouse Cytoplasmic Dynein Intermediate Chains: Identification of New Isoforms, Alternative Splicing and Tissue Distribution of Transcripts. PLOS ONE , 5 (7) , Article e11682. 10.1371/journal.pone.0011682. Green open access
file

Lana-Elola, E; Watson-Scales, S; Slender, A; Abucewicz, D; Martineau, A; Douglas, C; Mohun, T; (2014) A newly engineered high-resolution mapping panel to identify dosage-sensitive genes in Down syndrome-associated heart defects. TRANSGENIC RESEARCH , 23 (5) 905 - 905.

Lana-Elola, E; Watson-Scales, SD; Fisher, EMC; Tybulewicz, VLJ; (2011) Down syndrome: searching for the genetic culprits. DIS MODEL MECH , 4 (5) 586 - 595. 10.1242/dmm.008078. Gold open access

Lindquist, SG; Braendgaard, H; Svenstrup, K; Isaacs, AM; Neilsen, JE; The-FReJA-Consortium, ; (2008) Frontotemporal dementia linked to chromosome 3 (FTD-3)– current concepts and the detection of a previously unknown branch of the Danish FTD-3 family. Eu. J.Neurology , 15 667 - 670.

Lindquist, SG; Braendgaard, H; Svenstrup, K; Isaacs, AM; Nielsen, JE; FReJA Consortium, ; (2008) Frontotemporal dementia linked to chromosome 3 (FTD-3) - current concepts and the detection of a previously unknown branch of the Danish FTD-3 family. EUR J NEUROL , 15 (7) 667 - 670. 10.1111/j.1468-1331.2008.02144.x.

Lloyd, S.E.; Onwuazor, O.N.; Beck, J.A.; Mallinson, G.; Farrall, M.; Targonski, P.; Collinge, J.; (2001) Identification of multiple quantitative trait loci linked to prion disease incubation period in mice. Proceedings of the National Academy of Sciences , 98 (11) pp. 6279-6283. 10.1073/pnas.101130398.

Lloyd, SE; Onwuazor, ON; Beck, JA; Mallinson, G; Farrall, M; Targonski, P; Collinge, J; (2001) Identification of multiple quantitative trait loci linked to prion disease incubation period in mice. P NATL ACAD SCI USA , 98 (11) 6279 - 6283.

Lloyd, SE; Thompson, SR; Beek, JA; Linehan, JM; Wadsworth, JDF; Brandner, S; Collinge, J; (2004) Identification and characterization of a novel mouse prion gene allele. MAMM GENOME , 15 (5) 383 - 389. 10.1077/s00335-004-3041-5.

Lloyd, SE; Uphill, JB; Targonski, PV; Fisher, EMC; Collinge, J; (2002) Identification of genetic loci affecting mouse-adapted bovine spongiform encephalopathy incubation time in mice. NEUROGENETICS , 4 (2) 77 - 81. 10.1007/s10048-002-0133-9.

Lunau, L; Mouridsen, K; Rodell, A; Ostergaard, L; Nielsen, JE; Isaacs, A; Johannsen, P; (2012) Presymptomatic cerebral blood flow changes in CHMP2B mutation carriers of familial frontotemporal dementia (FTD-3), measured with MRI. BMJ Open , 2 (2) e000368 - ?. 10.1136/bmjopen-2011-000368. Gold open access

Ma, D; Cardoso, MJ; Modat, M; Powell, N; Wells, J; Holmes, H; Wiseman, F; (2014) Automatic structural parcellation of mouse brain MRI using multi-atlas label fusion. PLoS One , 9 (1) , Article e86576. 10.1371/journal.pone.0086576. Green open access
file

Martin, JE; Fisher, EMC; (1997) Phenotypic analysis - making the most of your mouse. Trends Genet. , 13 254 - ?.

Martin, JE; Shaw, GLCF; Donnithorne, JC; Peters, J; Rogers, DC; Fisher, EMC; (1998) Validation of the SHIRPA protocol for phenotype analysis of normal, mutant and gene targeted mice - age, sex, weight and the effects of repeat testing. J PATHOL , 186 4A - 4A.

Matthews, D; Fry, L; Powles, A; Weber, J; McCarthy, M; Fisher, EMC; Davies, K; (1996) Evidence for a locus for familial psoriasis mapping to chromosome 4q. Nature genetics , 14 231 - 233.

McGoldrick, P; Joyce, PI; Fisher, EM; Greensmith, L; (2013) Rodent models of amyotrophic lateral sclerosis. Biochim Biophys Acta , 1832 (9) 1421 - 1436. 10.1016/j.bbadis.2013.03.012.

Mead, S; Beck, J; Dickinson, A; Fisher, EMC; Collinge, J; (2000) Examination of the human prion protein-like gene Doppel for genetic susceptibility to sporadic and variant Creutzfeldt-Jakob disease. NEUROSCI LETT , 290 (2) 117 - 120.

Mead, S; Mahal, S; Beck, J; Farall, M; Fisher, EMC; Collinge, J; (2002) Identification of new prion disease susceptibility loci. J NEUROL NEUROSUR PS , 73 (2) 223 - 223.

Mead, S; Mahal, SP; Beck, J; Campbell, T; Farrall, M; Fisher, E; Collinge, J; (2001) Sporadic - but not variant - Creutzfeldt-Jakob disease is associated with polymorphisms upstream of PRNP Exon 1. AM J HUM GENET , 69 (6) 1225 - 1235.

Mead, S; Stumpf, MPH; Whitfield, J; Beck, JA; Poulter, M; Campbell, T; Uphill, JB; (2003) Balancing selection at the prion protein gene consistent with prehistoric kurulike epidemics. SCIENCE , 300 (5619) 640 - 643. 10.1126/science.1083320.

Mead, S.; Stumpf, M.P.H.; Whitfield, J.; Beck, J.A.; Poulter, M.; Campbell, T.; Uphill, J.B.; (2003) Balancing selection at the prion protein gene consistent with prehistoric kurulike epidemics. Science , 300 (5619) pp. 640-643. 10.1126/science.1083320.

Mead, SH; Mahal, SP; Farrall, M; Fisher, EMC; Collinge, J; (2001) Association of prion protein gene single nucleotide polymorphism haplotypes with Creutzfeldt-Jakob disease. AM J HUM GENET , 69 (4) 182 - 182.

Mensah, A; Mulligan, C; Linehan, J; Ruf, S; O'Doherty, A; Grygalewicz, B; Shipley, J; (2007) An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model. BMC Developmental Biology , 7 , Article 131. 10.1186/1471-213X-7-131. Green open access
file

Miller, G; Neilan, M; Chia, R; Gheryani, N; Holt, N; Charbit, A; Wells, S; (2010) ENU Mutagenesis Reveals a Novel Phenotype of Reduced Limb Strength in Mice Lacking Fibrillin 2. PLOS ONE , 5 (2) , Article e9137. 10.1371/journal.pone.0009137. Green open access
file

Mizielinska, S; Grönke, S; Niccoli, T; Ridler, CE; Clayton, EL; Devoy, A; Moens, T; (2014) C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins. Science 10.1126/science.1256800. Green open access
file

Moran, TH; Reeves, RH; Rogers, D; Fisher, EMC; (1996) Ain't misbehavin' - it's genetic. Nature Genetics , 12 115 - 116.

Morice, E; Andreae, LC; Cooke, SF; Vanes, L; Fisher, EMC; Tybulewicz, VLJ; Bliss, TVP; (2008) Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome. LEARN MEMORY , 15 (7) 492 - 500. 10.1101/lm.969608.

Morice, E.; Andreae, L.C.; Cooke, S.F.; Vanes, L.; Fisher, E.M.C.; Tybulewicz, V.L.J.; Bliss, T.V.P.; (2008) Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome. Learning & Memory , 15 (7) pp. 492-500. 10.1101/lm.969608. Green open access
file

NASIR, J; FISHER, EMC; BROCKDORFF, N; DISTECHE, C; LYON, MF; BROWN, SDM; (1990) UNUSUAL MOLECULAR CHARACTERISTICS OF A REPEAT SEQUENCE ISLAND WITHIN A GIEMSA POSITIVE BAND ON THE MOUSE X-CHROMOSOME. GENET RES , 55 (2) 126 - 126.

NASIR, J; FISHER, EMC; BROCKDORFF, N; DISTECHE, CM; LYON, MF; BROWN, SDM; (1990) UNUSUAL MOLECULAR CHARACTERISTICS OF A REPEAT SEQUENCE ISLAND WITHIN A GIEMSA-POSITIVE BAND ON THE MOUSE X-CHROMOSOME. P NATL ACAD SCI USA , 87 (1) 399 - 403.

NASIR, J; FISHER, EMC; BROCKDORFF, N; LYON, MF; BROWN, SDM; (1988) A NOVEL REPEAT SEQUENCE ISLAND ON THE MOUSE X-CHROMOSOME. GENET RES , 52 (1) 69 - 69.

Need, AC; Ge, DL; Weale, ME; Maia, J; Feng, S; Heinzen, EL; Shianna, KV; (2009) A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia. PLOS GENET , 5 (2) , Article e1000373. 10.1371/journal.pgen.1000373. Green open access
file

Nicholson, SJ; Witherden, AS; Hafezparast, M; Martin, JE; Fisher, EMC; (2000) Mice, the motor system and human motor neuron pathology. Mammalian Genome , 11 (12) 1041 - 1052.

Nielsen, TT; Mizielinska, S; Hasholt, L; Isaacs, AM; Nielsen, JE; FReJA Consortium, ; (2012) Reversal of pathology in CHMP2B-mediated frontotemporal dementia patient cells using RNA interference. J Gene Med , 14 (8) 521 - 529. 10.1002/jgm.2649.

Nolan, PM; Peters, J; Strivens, M; Rogers, D; Hagan, J; Spurr, N; Gray, IC; (2000) A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. NAT GENET , 25 (4) 440 - 443.

Nolan, PM; Peters, J; Vizor, L; Strivens, M; Washbourne, R; Hough, T; Wells, C; (2000) Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource. MAMM GENOME , 11 (7) 500 - 506.

O'Doherty, A; Ruf, S; Mulligan, C; Hildreth, V; Errington, ML; Cooke, S; Sesay, A; (2005) An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes. SCIENCE , 309 (5743) 2033 - 2037. 10.1126/science.1114535.

Page, DC; Fisher, EMC; McGillivray, B; Brown, LG; (1990) Additional deletion in sex-determining region of human Y chromosome resolves paradox of X,t(Y;22) female. Nature , 346 279 - 281.

Page, DC; Mosher, R; Simpson, EM; Fisher, EMC; Mardon, G; Pollack, J; McGillivray, B; (1987) The sex determining region of the human Y chromosome encodes a finger protein. Cell , 51 1091 - 1104.

Parkinson, N; Ince, PG; Smith, MO; Highley, R; Skibinski, G; Andersen, PM; Morrison, KE; (2006) ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B). NEUROLOGY , 67 (6) 1074 - 1077.

Pfister, KK; Fisher, EMC; Gibbons, IR; Hays, TS; Holzbaur, ELF; McIntosh, JR; Porter, ME; (2005) Cytoplasmic dynein nomenclature. J CELL BIOL , 171 (3) 411 - 413. 10.1083/jcb.200508078.

Pfister, KK; Shah, PR; Hummerich, H; Russ, A; Cotton, J; Annuar, AA; King, SM; (2006) Genetic analysis of the cytoplasmic dynein subunit families. PLoS Genetics , 2 (1) , Article E1. 10.1371/journal.pgen.0020001. Green open access
file

Prasher, V; Farrer, MJ; Kessling, AM; Fisher, EMC; West, RJ; Barber, PC; Butler, AC; (1998) Molecular mapping of Alzheimer- type dementia in Down syndrome. Ann. Neurol , 43 380 - ?.

Ramos, VC; Vidal-Taboada, J; Bergonon, S; Egeo, A; Fisher, EMC; Scartezzini, P; Oliva, R; (2002) Characterisation and expression analysis of the WDR9 gene, located in the Down critical region-2 of the human chromosome 21. Biochim Biophys Acta , 1577 (3) 377 - 383.

Ramos, VC; Vidal-Taboada, JM; Bergonon, S; Egeo, A; Fisher, EMC; Scartezzini, P; Oliva, R; (2002) Characterisation and expression analysis of the WDR9 gene, located in the Down critical region-2 of the human chromosome 21. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression , 1577 (3) 377 - 383.

Rastan, S; Hough, T; Kierman, A; Hardisty, R; Erven, A; Gray, IC; Voeling, S; (2004) Towards a mutant map of the mouse - new models of neurological, behavioural, deafness, bone, renal and blood disorders. GENETICA , 122 (1) 47 - 49.

Reynolds, LE; Watson, AR; Baker, M; Jones, TA; D'Amico, G; Robinson, SD; Joffre, C; (2010) Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome. NATURE , 465 (7299) 813 - U13. 10.1038/nature09106.

Ricketts, T; McGoldrick, P; Fratta, P; de Oliveira, HM; Kent, R; Phatak, V; Brandner, S; (2014) A nonsense mutation in mouse tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects. PLoS One , 9 (1) , Article e85962. 10.1371/journal.pone.0085962. Green open access
file

Rishal, I; Kam, N; Perry, R; Shinder, V; Fisher, EMC; Schiavo, G; Fainzilber, M; (2012) A motor-driven mechanism for cell-length sensing. Cell Reports , 1 (608-616)

Robson, JC; Bowen, S; Ball, S; Fisher, EM; Gupta, S; Nickols, C; Parkinson, LC; (2002) Gene dose effects in "Gammy": A mouse model of human club foot. J PATHOL , 198 51A - 51A.

Rogers, DC; Fisher, EMC; Brown, SDM; Peters, J; Hunter, AJ; Martin, JE; (1997) Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment. MAMM GENOME , 8 (10) 711 - 713.

Rogers, DC; Peters, J; Martin, JE; Ball, S; Nicholson, SJ; Witherden, AS; Hafezparast, M; (2001) SHIRPA, a protocol for behavioral assessment: validation for longitudinal study of neurological dysfunction in mice. NEUROSCI LETT , 306 (1-2) 89 - 92.

Rohrer, JD; Ahsan, RL; Isaacs, AM; Neilsen, JE; Ostergaard, L; Scahill, R; Warren, JD; (2009) Presymptomatic generalised brain atrophy in frontotemporal dementia caused by CHMP2B mutation. Dement. Geriatr. Cogn. Disord. , 27 182 - 186.

Rohrer, JD; Ahsan, RL; Isaacs, AM; Nielsen, JE; Ostergaard, L; Scahill, R; Warren, JD; (2009) Presymptomatic Generalized Brain Atrophy in Frontotemporal Dementia Caused by CHMP2B Mutation. DEMENT GERIATR COGN , 27 (2) 182 - 186. 10.1159/000200466.

Ruparelia, A; Wiseman, F; Sheppard, O; Tybulewicz, VL; Fisher, EM; (2010) Down syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21. J Biomed Res , 24 (2) 87 - 99. 10.1016/S1674-8301(10)60016-4. Gold open access

Saccon, RA; Bunton-Stasyshyn, RK; Fisher, EM; Fratta, P; (2013) Is SOD1 loss of function involved in amyotrophic lateral sclerosis? Brain , 136 (Pt 8) 2342 - 2358. 10.1093/brain/awt097.

Schiavo, G; Greensmith, L; Hafezparast, M; Fisher, EM; (2013) Cytoplasmic dynein heavy chain: the servant of many masters. Trends Neurosci , 36 (11) pp. 641-651. 10.1016/j.tins.2013.08.001. Green open access
file

Schmitt, K; Lazzeroni, LC; Vollrath, D; Foote, S; Fisher, EMC; Goradia, TM; Lange, K; (1994) Multipoint linkage map of the human pseudoautosomal region based on single sperm typing: Do double crossovers occur during male meiosis? Am. J. Hum. Genet. , 55 423 - 430.

Schmitt, K; Vollrath, D; Foote, S; Fisher, EMC; Page, DC; Arnheim, N; (1993) Four PCR-based polymorphisms in the pseudoautosomal region of the human X and Y chromosomes. Hum Mol Genet , 2 1978 - ?.

Shah, PR; Ahmad-Annuar, A; Ahmadi, KR; Russ, C; Sapp, PC; Horvitz, HR; Brown, RH; (2006) No association of DYNC1H1 with sporadic ALS in a case-control study of a northern European derived population: A tagging SNP approach. AMYOTROPH LATERAL SC , 7 (1) 46 - 56. 10.1080/14660820500397057.

Sheppard, O; Plattner, F; Rubin, A; Slender, A; Linehan, JM; Brandner, S; Tybulewicz, VL; (2011) Altered regulation of tau phosphorylation in a mouse model of down syndrome aging. Neurobiol Aging , 33 (4) 828.e31-828.e44. 10.1016/j.neurobiolaging.2011.06.025. Gold open access

Sheppard, O; Wiseman, FK; Ruparelia, A; Tybulewicz, VL; Fisher, EM; (2012) Mouse models of aneuploidy. ScientificWorldJournal , 2012 214078 - ?. 10.1100/2012/214078. Gold open access

Skibinski, G; Parkinson, NJ; Brown, JM; Chakrabarti, L; Lloyd, SL; Hummerich, H; Nielsen, JE; (2005) Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia. NAT GENET , 37 (8) 806 - 808. 10.1038/ng1609.

Stevens, JC; Banks, GT; Festing, MFW; Fisher, EMC; (2007) Quiet mutations in inbred strains of mice. TRENDS MOL MED , 13 (12) 512 - 519. 10.1016/j.molmed.2007.10.001.

Stevens, JC; Chia, R; Hendriks, WT; Bros-Facer, V; van Minnen, J; Martin, JE; Jackson, GS; (2010) Modification of Superoxide Dismutase 1 (SOD1) Properties by a GFP Tag - Implications for Research into Amyotrophic Lateral Sclerosis (ALS). PLOS ONE , 5 (3) , Article e9541. 10.1371/journal.pone.0009541. Green open access
file

Stevens, JC; Fisher, EMC; Mead, S; (2011) How does the genetic assassin select its neuronal target? MAMM GENOME , 22 (3-4) 139 - 147. 10.1007/s00335-011-9319-5.

Stokholm, J; Teasdale, T; Johannsen, P; Nielsen, J; Nielsen, T; Isaacs, A; Brown, J; (2013) Cognitive impairment in athe preclinical stage of dementia in FTD-3 CHMP2B mutation carriers: a longitudinal prospective study. Journal of Neurology, Neurosurgery and Psychiatry (84) 170 - 176.

Strydom, A; Consortium, L; (2013) THE LONDOWNS CONSORTIUM - INVESTIGATING COGNITION AND ALZHEIMER'S DISEASE IN DOWN'S SYNDROME. JOURNAL OF INTELLECTUAL DISABILITY RESEARCH , 57 (9) 801 - 801.

Thorne, T; Fratta, P; Hanna, MG; Cortese, A; Plagnol, V; Fisher, EM; Stumpf, MP; (2013) Graphical modelling of molecular networks underlying sporadic inclusion body myositis. Mol Biosyst , 9 (7) 1736 - 1742. 10.1039/c3mb25497f.

Tsipouri, V; Curtin, JA; Nolan, PM; Vizor, L; Parsons, CA; Clapham, CM; Latham, ID; (2004) Three novel pigmentation mutants generated by genome-wide random ENU mutagenesis in the mouse. COMP FUNCT GENOM , 5 (2) 123 - 127. 10.1002/cfg.382. Gold open access

Tsipouri, V; Hough, T; Curtin, JA; Guionaud, S; Fulleylove, M; Vizor, L; Hoult, D; (2004) An ENU-induced, low-cholesterol, low-HDL cholesterol mouse mutant carries an Abca1 point mutation and is a model for Tangier disease and familial hypoalphalipoproteinemia. Comparative and Functional Genomics , 5 123 - 127.

Tybulewicz, VLJ; Fisher, EMC; (2006) New techniques to understand chromosome dosage: mouse models of aneuploidy. HUM MOL GENET , 15 R103 - R109. 10.1093/hmg/ddl179.

Urwin, H; Authier, A; Nielsen, JE; Metcalf, D; Powell, C; Froud, K; Malcolm, DS; (2010) Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations. HUM MOL GENET , 19 (11) 2228 - 2238. 10.1093/hmg/ddq100.

Urwin, H; Josephs, KA; Rohrer, JD; Mackenzie, IR; Neumann, M; Authier, A; Seelaar, H; (2010) FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration. ACTA NEUROPATHOL , 120 (1) 33 - 41. 10.1007/s00401-010-0698-6.

Vidal-Taboada, JM; Bergonon, S; Sanchez, M; Lopez-Acdeo, C; Groet, J; Nizetic, D; Katsanis, N; (1998) A 342kb ready-to-sequence PAC and cosmid contig with full EcoRI/SMAI restriction map between markers ACTL5 and D21S268 within the Down syndrome region-2. Biochem. Biophys. Res. Comm. , 243 572 - ?.

Wang, W; Fisher, EMC; Jia, Q; Dunn, JM; Porfiri, E; Downward, J; Egan, SE; (1995) The Grb2 binding domain of mSos1 is not required for downstream signal transduction. Nature Genetics , 10 294 - 299.

Wang, Y; Mulligan, C; Denyer, G; Delom, F; Dagna-Bricarelli, F; Tybulewicz, VLJ; Fisher, EMC; (2009) Quantitative Proteomics Characterization of a Mouse Embryonic Stem Cell Model of Down Syndrome. MOL CELL PROTEOMICS , 8 (4) 585 - 595. 10.1074/mcp.M800256-MCP200.

Ward, CL; Fisher, EMC; Ball, ST; Peters, J; Martin, JE; (1999) Novel mouse mutant with motor dysfunction from phenotype to genotype. J PATHOL , 187 23A - 23A.

Washbourne, R; Nolan, P; Peters, J; Vizor, L; Hewitt, M; Sellley, R; Strivens, M; (2000) Identification of novel behavioural mutations using ENU mutagenesis. EUR J NEUROSCI , 12 235 - 235.

Watson-Scales, S; Lana-Elola, E; Williamson, M; Slender, A; Abucewicz, D; Fisher, E; Tybulewicz, V; (2014) A newly engineered high-resolution mapping panel to identify dosage-sensitive genes in Down syndrome-associated motor defects. TRANSGENIC RESEARCH , 23 (5) 904 - 904.

Wiggins, LM; Kuta, A; Stevens, JC; Fisher, EM; von Bartheld, CS; (2012) A novel phenotype for the dynein heavy chain mutation Loa: altered dendritic morphology, organelle density, and reduced numbers of trigeminal motoneurons. J Comp Neurol , 520 (12) 2757 - 2773. 10.1002/cne.23085.

Wills, AM; Cronin, S; Slowik, A; Kasperaviciute, D; Van Es, MA; Morahan, JM; Valdmanis, PN; (2009) A large-scale international meta-analysis of paraoxonase gene polymorphisms in sporadic ALS. NEUROLOGY , 73 (1) 16 - 24. 10.1212/WNL.0b013e3181a18674.

Wilson, MD; Barbosa-Morais, NL; Schmidt, D; Conboy, CM; Vanes, L; Tybulewicz, VLJ; Fisher, EMC; (2008) Species-specific transcription in mice carrying human chromosome 21. SCIENCE , 322 (5900) 434 - 438. 10.1126/science.1160930.

Wiseman, FK; Alford, KA; Tybulewicz, VLJ; Fisher, EMC; (2009) Down syndrome-recent progress and future prospects. HUM MOL GENET , 18 R75 - R83. 10.1093/hmg/ddp010. Green open access
file

Wiseman, FK; Sheppard, O; Linehan, JM; Brandner, S; Tybulewicz, VL; Fisher, EM; (2010) Generation of a panel of antibodies against proteins encoded on human chromosome 21. J Negat Results Biomed , 9 7 - ?. 10.1186/1477-5751-9-7.

Witherden, AS; Hafezparast, M; Nicholson, SJ; Ahmad-Annuar, A; Bermingham, N; Arac, D; Rankin, J; (2002) An integrated genetic, radiation hybrid, physical and transcription map of a region of distal mouse chromosome 12, including an imprinted locus and the 'Legs at odd angles' (Loa) mutation. GENE , 283 (1-2) 71 - 82.

Witherden, AS; Nicholson, SJ; Fisher, EMC; (1997) The value of mouse mutants. Mouse Genome , 95 856 - 874.

Yulug, IG; Egan, SE; Pollock, PM; Fisher, EMC; (1993) A homologue of the Drosophila Son of Sevenless gene maps to mouse chromosome 17. Genomics , 18 733 - 734.

Yulug, IG; Egan, SE; See, CG; Fisher, EMC; (1995) Mapping human SHC, a gene that encodes an adaptor protein and identifying and mapping a SHC related sequence. Hum. Genet. , 96 245 - 248.

Yulug, IG; Egan, SE; See, CG; Fisher, EMC; (1994) Mapping GRB2, a signal transduction gene in the human and the mouse. Genomics , 22 313 - 318.

Yulug, IG; Fisher, EMC; (1995) The frequency and position of Alu repeats in cDNAs, as determined by database searching. Genomics , 27 544 - 548.

Yulug, IG; Hillermann, R; Fisher, EMC; (1994) The SHB adaptor protein maps to human chromosome 9. Genomics , 24 615 - 617.

Yulug, IG; Katsanis, N; de-Belleroche, J; Collinge, J; Fisher, EMC; (1995) An improved protocol for the analysis of SOD1 gene mutations, and a new mutation in exon 4. Hum Mol Genet , 4 1101 - 1104.

Yulug, IG; Killary, AM; Sandhu, AK; Athwal, RS; Fox, M; Fisher, EMC; (1995) Gene expression in response to retinoic acid in novel human chromosome 21 monochromosomal cell hybrids. SOMAT CELL MOLEC GEN , 21 (5) 357 - 365.

Yulug, IG; See, CG; Fisher, EMC; (1995) The DAD1 protein, whose defect causes apoptotic cell death, maps to human chromosome 14. Genomics , 26 433 - 435.

Zinn, AR; Page, DC; Fisher, EMC; (1993) Turner syndrome: the case of the missing sex chromosome. Trends Genet , 9 90 - 93.

van de Leemput, J; Chandran, J; Knight, MA; Holtzclaw, LA; Scholz, S; Cookson, MR; Houlden, H; (2007) Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans. PLoS Genetics , 3 (6) , Article e108. 10.1371/journal.pgen.0030108. Green open access
file

van de Leemput, J; Wavrant-De Vrieze, F; Rafferty, I; Bras, JM; Giunti, P; Fisher, EMC; Hardy, JA; (2010) Sequencing Analysis of the ITPR1 Gene in a Pure Autosomal Dominant Spinocerebellar Ataxia Series. MOVEMENT DISORD , 25 (6) 771 - 773. 10.1002/mds.22970.

van der Zee, J; Urwin, H; Engelborghs, S; Bruyland, M; Vandenberghe, R; Dermaut, B; De Pooter, T; (2008) CHMP2B C-truncating mutations in frontotemporal lobar degeneration are associated with an aberrant endosomal phenotype in vitro. HUM MOL GENET , 17 (2) 313 - 322. 10.1093/hmg/ddm309.

Book

UNSPECIFIED (Ed). (1998) Methods in Mouse Genetics and Genome Mapping. Academic Press: New York.

UNSPECIFIED (Ed). Enjoy writing your science thesis or dissertation. Imperial College Press: London UK.

Book chapter

Ballabio, A; Brown, SDM; Fisher, EMC; (1997) Strategies for disease identification. In: Genome Analysis: A laboratory manual. Cold Spring Harbor Laboratory Press: Cold Spring Harbor.

Fisher, EMC; (1994) Genetics, molecular and cell biology. In: Kumar, PJ and Clark, ML, (eds.) Clinical Medicine. Balliere Tindall: London.

Proceedings paper

Acevedo-Arozena, A; Corrochano, S; Ricketts, T; Carter, S; Ribinsztein, DC; Fisher, EMC; Brown, SDM; Sensitised ENU screens for Huntingtons Disease and Amyotrophic Lateral Sclerosis. In: (Proceedings) Society for Neuroscience meeting 2009.

Acevedo-Arozena, A; Ricketts, T; Kalmar, B; Kent, R; Greensmith, L; Fisher, EMC; Using ENU mutagenesis to search for modifiers of SOD1 ALS in the mouse. In: (Proceedings) 20th International Symposium on ALS/MND.

Acevedo-Arozena, A; Ricketts, T; Kalmar, B; Kent, R; Greensmith, L; Fisher, EMC; A mutagenesis strategy to find SOD1 ALS modifiers in the mouse. In: (Proceedings) 20th International Symposium on ALS/MND.

Acevedo-Arozena, A; Rowe, C; Fisher, EMC; Searching for SOD1 ALS modifiers in the mouse. In: (Proceedings) International Mammalian Genome Conference.

Acevedo-Arozena, A; Rowe, C; Fisher, EMC; A mutagenesis strategy to find SOD1 ALS modifiers in the mouse. In: (Proceedings) 6th FENS forum for European Neuroscientists.

Achilli, F; Boyle, S; Kieran, D; Chia, R; Hafezparast, M; Martin, JE; Schiavo, G; (2005) The SOD1 transgene in the G93A mouse model of amyotrophic lateral sclerosis lies on distal mouse chromosome 12. In: ALS and Other MNDs.

Achilli, F; Nolan, P; Fisher, EMC; Characterisation of new mice models of motor neuron disease. In: (Proceedings) 18th International Mouse Genome Conference.

Achilli, F; Nolan, P; Lalanne, Z; Hardy, A; Booker, D; Strand, K; Revesz, T; Characterisation of new locomotor mutants. In: (Proceedings) 19th International Mouse Genome Conference.

Ahmad-Annuar, A; Hafezparast, M; Witherden, A; Ball, S; Hummerich, H; Peters, J; Martin, JE; Legs at odd angles: a mouse mutant for motor neuron degeneration. In: (Proceedings) Fourth Workshop on Mouse Molecular Genetics.

Ahmad-Annuar, A; Hafezparast, M; Witherden, A; Ball, S; Peters, J; Martin, JE; Fisher, EMC; Legs at odd angles: a mouse mutant with a neuronal deficit. In: (Proceedings) 15th International Mouse Genome conference.

Ahmad-Annuar, A; Shah, P; Hafezparast, M; Goldstein, D; Fisher, EMC; Linkage disequilibrium and haplotype mapping of the human cytoplasmic dynein heavy chain 1 gene. In: (Proceedings) Graduate School of Life Sciences and Medicine Student Symposium, Imperial College.

Ahmad-Annuar, A; Shah, P; Hafezparast, M; Goldstein, DB; Fisher, EMC; (2003) Linkage disequilibrium and haplotype mapping of the human cytoplasmic dynein heavy chain 1 gene on chromosome 14q32. In: AMERICAN JOURNAL OF HUMAN GENETICS. (pp. 487 - 487). UNIV CHICAGO PRESS

Airey, J; Washbourne, R; Peters, J; Vizor, L; Tymowska-Lalanne, Z; Smythe, S; Martin, J; Analysis of ENU-induced mutations exhibiting an elevated acoustic startle response. In: (Proceedings) 15th International Mouse Genome conference.

AlQatari, M; Vastani, N; Bros-Facer, V; Groves, M; Greensmith, L; Fisher, EM; Koltzenburg, M; (2009) A MUTATION OF THE CYTOPLASMIC DYNEIN HEAVY CHAIN GENE Dync1h1 CAUSES A SEVERE SENSORY NEUROPATHY. In: JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM. (pp. 6 - 6). WILEY-BLACKWELL PUBLISHING, INC

Alford, KA; Vanes, L; Fisher, EMC; Tybulewicz, VLJ; A myeloproliferative disorder in the Tc1 mouse model of Down syndrome. In: (Proceedings) Modern trends in human leukemia, Wilsede Meeting XV11.

Alford, KA; Vanes, L; Li, Z; Orkin, SH; Fisher, EMC; Tybulewicz, VLJ; (2008) A Myeloproliferative Disorder in the Tel Mouse Model of Down Syndrome. In: BLOOD. (pp. 964 - 964). AMER SOC HEMATOLOGY

Ali-Morsi, A; Stoddart, E; Bros-Facer, V; Fisher, EMC; Greensmith, L; Hafezparast, M; Investigating why dynein mutation ameliorates the SOD1 ALS phenotype and considerably extends lifespan. In:

Ateh, DD; Hussain, I; Mustafa, A; Price, KM; Nickols, CD; Bird, MM; Greensmith, L; (2006) Normal subcellular distribution of dynein-dynactin complex subunits and disturbances in neurodegenerative disease. In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. (pp. 234 - 235). BLACKWELL PUBLISHING

Ateh, DD; Hussain, I; Mustafa, A; Price, KM; Nickols, CD; Bird, MM; Greensmith, L; (2006) Subcellular functional specificity of dynein-dynactin complex subunits - normal distribution and disturbances in neurodegenerative disease. In: JOURNAL OF PATHOLOGY. (pp. 23A - 23A). JOHN WILEY & SONS LTD

Baker, CS; Price, KM; Bowen, S; Hafezparast, M; Ahmad-Annuar, A; Peters, J; Fisher, EMC; Protein studies of the Loa mutant. In: (Proceedings) 13th International Symposium on ALS/MND.

Baker, CS; Price, KM; Bowen, S; Walker, KE; Chana, S; Fisher, EMC; Martin, JE; (2003) Protein characterisation of the Loa mouse. In: Amyotroph. Lateral Scler Other Motor Neuron Disord. (pp. 5 - 227).

Banks, G; Fisher, EMC; A functional dissection of the dynein complex by genetic screening in mice. In: (Proceedings) EMBO/FEBS Workshop on Systems Dynamics of Intracellular Communications.

Banks, G; Kuta, A; Bros-Facer, V; Schiavo, G; Koltzenburg, M; Greensmith, L; Fisher, EMC; Working with mouse mutants to uncover the roles of transport proteins. In: (Proceedings) EMBO Conference on spatial dynamics of intracellular communication - overcoming distance in signalling networks.

Bermingham, N; Martin, JE; Fisher, EMC; Fine mapping the MND locus and mouse chromosome 8. In: (Proceedings) Mouse Molecular Genetics Meeting.

Bermingham, N; Peters, J; Martin, JE; Fisher, EMC; Characterisation of three new mouse mutants with neuromuscular deficits. In: (Proceedings) Mouse Molecular Neurogenetics Meeting.

Bermingham, N; Peters, J; Martin, JE; Fisher, EMC; Positional cloning of legs at odd angles (Loa). In: (Proceedings) Ninth Mouse Genome meeting.

Bermingham, N; Peters, J; Rogers, D; Martin, J; Fisher, EMC; Positional cloning of the neurological mutant: Legs at odd angles (Loa). In: (Proceedings) Second Mouse Molecular Neurogenetics Meeting.

Bermingham, N; Peters, J; Rogers, D; Martin, J; Fisher, EMC; The neurological mutant: legs at odd angles (Loa). In: (Proceedings) 10th International Mouse Genome Conference.

Bowen, S; Bird, MM; Deinhardt, K; Price, KM; Baker, CS; Robson, JC; Swash, M; Phagocytosis of cell and non-cell debris by neurons in vitro and in vivo. In: (Proceedings) 15th International ALS symposium.

Bros, V; Golding, M; Chia, R; Schiavo, G; Flenniken, A; Adamson, SL; Rossant, J; The Arl mouse - a new mouse strain with a mutation in the cytoplasmic dynein heavy chain. In: (Proceedings) Mutant SOD1 and ALS: from the molecule to man.

Bros, V; Golding, M; Schiavo, G; Chia, R; Philpott, A; Flenniken, A; Adamson, SL; The Arl mouse - a new mouse strain with a mutation in the cytoplasmic dynein heavy chain. In: (Proceedings) EMBO/FEBS Workshop on Systems Dynamics of Intracellular Communications.

Bros-Facer, V; Baisland, L; Hafezparast, M; Fisher, EMC; Duchen, M; Schiavo, G; Greensmith, L; The effects of a dynein mutation on mitochondria in SOD1 motoneurons. In: (Proceedings) 19th International Symposium on ALS/MND.

Bros-Facer, V; Banks, GT; Williams, H; Greensmith, L; Fisher, EMC; A novel mutation in glycine tRNA synthetase ameliorates SOD1G93A motor neuron degeneration. In: (Proceedings) 19th International Symposium on ALS/MND.

Brown, J; Gydesen, S; Johannsen, P; Gade, A; Skinbinski, G; Chakrabarti, L; Brun, A; Frontotemporal dementia linked to chromosome 3 (FTD3). In: (Proceedings) 14th International Conference on Frontotemporal Dementia.

Brown, J; The-FReJA-Consortium, ; Clinical features of frontotemporal demential linked to chromosome 3 - FTD3. In: (Proceedings) 4th International Conference on Frontotemporal Dementia.

Brown, JM; Isaacs, A; Neilsen, J; The-FReJA-Consortium, ; Mutations in the endosomal ESCRT-III complex in frontotemporal dementia. In: Alzheimer's & Dementia. (pp. S419 - S419).

Brown, S; Peters, J; Nolan, P; Vizor, L; Thornton, C; Glenister, P; Greenaway, S; A comprehensive ENU mutagenesis programme for the mouse genome. In: (Proceedings) Mouse molecular genetics.

Brown, S; Peters, J; Vizor, L; Thornton, C; Glenister, P; Greenaway, S; Hewitt, M; Evaluation of neurological mouse mutants caused by ENU mutagenesis. In: (Proceedings) EMBL Mouse Molecular Genetics Meeting.

Brown, S; Peters, J; Vizor, L; Thornton, C; Glenister, P; Greenaway, S; Hewitt, M; The mutant map of the mouse. In: (Proceedings) Genome Sequencing and Biology Meeting.

Brown, S; Peters, J; Vizor, L; Thornton, C; Glenister, P; Greenaway, S; Nolan, P; A comprehensive ENU mutagenesis programme for the mouse genome. In: Cytogenetics and Cell Genetics.

Brun, A; The-FReJA-Consortium, ; Pathology of FTD3. In: (Proceedings) International Conference on Frontotemporal Dementia.

Bunton-Stasyshyn, R; Devoy, A; Fisher, EMC; An investigation into the role of endogenousmouse Sod1 in the disease course of transgenic SOD1mouse models of amyotrophic lateral sclerosis. In: (Proceedings) American Society of Neuroscience Annual meeting.

Bunton-Stasyshyn, R; Devoy, A; Tybulewicz, V; A SOD1 humanising knock-in mouse model fo ALS with conditional point mutation. In: (Proceedings) Queen Square Student Symposium.

Bunton-Stasyshyn, R; Devoy, A; Tybulewicz, V; Fisher, EMC; A SOD1 humanising knock-in mouse model fo ALS with conditional point mutation. In: (Proceedings) Queen Square Student Symposium.

Bunton-Stasyshyn, R; Devoy, A; Tybulewicz, V; Fisher, EMC; A SOD1 humanising knock-in mouse model of ALS with conditional point mutation. In: (Proceedings) UCL Neuroscience Symposium.

Bunton-Stasyshyn, R; Devoy, A; Tybulewicz, VLJ; Fisher, EMC; A SOD1 humansing knock-in mouse model of ALS with conditional point mutation. In: (Proceedings) Mouse Genetics 2011 Conference.

Chakrabarti, L; Association, FFRIJ; Clinical and molecular characterisation of Frontotemporal dementia linked to Human Chromosome 2. In: (Proceedings) American Society of Human Genetics.

Chia, R; Achilli, F; Festing, MFW; Fisher, EMC; (2005) The origins and uses of mouse outbred stocks. In: ALS and Other MNDs.

Chia, R; Achilli, F; Festing, MFW; Fisher, EMC; The origins and uses of mouse outbred stocks. In: (Proceedings) 19th International Mouse Genome Conference.

Chia, R; Tattum, H; Clarke, A; Fisher, EMC; Jackson, GS; In vitro fibrillization of superoxide dismutatse type 1 (SOD1) suggests one possible mechanism by which mutations may lead to amyotrophic lateral sclerosis (ALS). In: (Proceedings) Keystone symposium: Molecular mechanisms of neurodegeneration.

Choong, X; Raha, A; Tybulewicz, V; Wiseman, F; Fisher, EMC; (2013) Identification of genes on Hsa21 influencing APP/A pathology using primary neuronal cultures from transgenic mice. In: (Proceedings) British Neuroscience Association.

Choong, X; Raha, A; Tybulewicz, V; Wiseman, F; Fisher, EMC; (2013) Using primary neurons from transgenic mice to identify genes on human chromosome 21 influencing Alzheimer neuropathology. In: (Proceedings) Alzheimer Association International Conference.

Choong, X; Raha, A; Tybulewicz, V; Wiseman, F; Fisher, EMC; (2013) Which genes on human chromosome 21, other than APP, influence Alzheimer neuropathology? In: (Proceedings) Alzheimers Research UK Annual Conference.

Cleary, J; Price, A; Thayyil, S; Schambler, P; Tybulewicz, VLJ; Fisher, EMC; Taylor, A; Towards 3D virtual histology using high-field magnetic resonance imaging. In: (Proceedings) British Association of Clinical Anatomists.

Cleary, JO; Norris, FC; Wiseman, FK; Price, AN; Choy, MK; Tybulewicz, VLJ; Ordidge, RJ; Optimised μMRI for Phenotyping the Tc1 Model of Down Syndrome. In: (Proceedings) Society for Magnetic Resonance in Medicine.

Cooke, SF; Errington, ML; O'Doherty, A; Sesay, A; Ruf, A; Vanes, L; Bliss, TVP; Insertion of human chromosome 21 into the mouse genome leads to impairments of hippocampal LTP and memory. In: (Proceedings) Society for Neuroscience.

Crawford, H; Wiseman, F; Fisher, EMC; Pocock, J; (2013) Clues to Down syndrome and Alzheimer’s disease: investigating microglial behaviour in the Tc1 mouse model. In: (Proceedings) UCL ION Student Symposium.

Curtin, JA; Tsipouri, V; Latham, I; Nolan, P; Hardisty, R; Vizor, L; Sims, MA; Rapid genome scan reveals linkage to mouse chromosome 15 for the ENU induced circling mouse mutant spin cycle, a potential model for DFNA17. In: (Proceedings) Mouse Initiatives III: Modeling the Human Genome & Disease.

Curtin, JA; Tsipouri, V; Latham, I; Nolan, P; Hardisty, R; Vizor, L; Sims, MA; (2001) Rapid genome scan reveals linkage to chromosome 15 for the ENU induced circling mouse mutant, spin cycle. In: Copp, AJ and Fisher, EMC, (eds.) Genetcis Research. (pp. 203 - ?). Cambridge Journals

Delabar, JM; Creau, N; Antonarakis, SE; Brahe, C; Estivill, X; Pritchard, M; Fisher, EMC; (1996) Towards an integrated chromosome 21 map: progress of the European chromosome 21 consortium. In: European Journal of Human Genetics.

Delabar, JM; Creau, N; Brahe, C; Fisher, EMC; Kessling, A; Potier, MC; Nizetic, D; European chromosome 21 consortium: two years achievements. In: European Journal of Human Genetics.

Devoy, A; Bunton-Stasyshyn, R; Tybulewicz, VLJ; Fisher, EMC; Making new mouse models of ALS. In: (Proceedings) 22nd International Symposium on ALS/MND.

Devoy, A; Fratta, P; Fisher, EMC; Making new mouse models of ALS. In: (Proceedings) MRC Centre for Translational Research - Scientific Advisory Board Review.

Devoy, A; Tybulewicz, VLJ; Fisher, EMC; A SOD1 humansing knock-in mouse model of ALS with conditional point mutation. In: (Proceedings) Mouse Genetics 2011 Conference.

Dunlevey, LPE; Fisher, EMC; Tybulewicz, VLJ; Mohun, T; Cardiac development in a mouse model of Down Syndrome (Tc1). In: (Proceedings) ESC WG Developmental Anatomy and Pathology meeting 2009.

Dunlevey, LPE; Fisher, EMC; Tybulewicz, VLJ; Mohun, T; Cardiac development in a mouse model of Down syndrome (Tc1). In: (Proceedings) First AnEUploidy Workshop.

Dunlevy, L; Fisher, EMC; Tybulewicz, VLJ; Mohun, T; Cardiac development in a mouse model of Down Syndrome (Tc1). In: (Proceedings) Weinstein Cardiovascular Development Conference.

Egan, SE; Fisher, EMC; Downward, J; (1994) Transformation by the mSos1 Ras exchange protein. In: J. Cell. Biochem. (pp. 234 - ?).

Errington, ML; Cooke, SF; O'Doherty, A; Ruf, S; Vanes, L; Bliss, TVP; Tybulewicz, VLJ; Insertion of human chromosome 21 into the mouse genome leads to impairments of memory and hippocampal LTP. In: (Proceedings) British Neuroscience Association.

Farrer, MH; Prasher, VP; Fisher, EMC; Kessling, AM; Phenotype/genotype mapping Alzheimer-type dementia in Down syndrome. In: American Journal of Human Genetics. (pp. 500 - ?).

Farrer, MJ; Fisher, EMC; Kessling, AM; Molecular genetic characterisation of six cases with partial chromosome 21 aneuploidy. In: European Journal of Human Genetics (Supp).

Fisher, EMC; Multiple mouse models for helping us understand ALS. In: (Proceedings) 2nd European ALS Research Workshop.

Fisher, EMC; Treating hybrid cell lines with retinoic acid. In: (Proceedings) Gordon Research Conference on Developmental Biology.

Fisher, EMC; The genetics of motor neurone disorders. In: (Proceedings) NIGMS Research Symposium Minority program..

Fisher, EMC; Alford, K; Dunlevy, L; Lana-Elola, E; Haas, M; Line, S; Reynolds, L; Recent data on the phenotype of the Tc1 mouse model of Down syndrome. In: (Proceedings) 2nd Aneuploidy Workshop.

Fisher, EMC; Brown, LG; Page, DC; Mapping the human Y chromosome. In: (Proceedings) Gordon Research Conference on Mammalian Gametogenesis and Embryogenesis.

Fisher, EMC; Bunton-Stasyshyn, R; Devoy, A; Tybulewicz, V; A SOD1 humanising knock-in mouse model of ALS with conditional point mutation. In: (Proceedings) Mouse Genetics 2011 Conference.

Fisher, EMC; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) International Society of Differentiation, Differentiation of Normal and Neoplastic Cells.

Fisher, EMC; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) 5th Tenovus Symposium on Eukaryotic genes.

Fisher, EMC; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) Fourth International Workshop on Mouse Molecular Genetics.

Fisher, EMC; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) EMBO/EMBL Molecular Approaches to Stem Cell Differentiation and Mouse Development.

Fisher, EMC; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) Mammalian Genetics Group/Mammalian Biochemical Genetics Group Conference.

Fisher, EMC; Cleary, JO; Norris, FC; Wiseman, FK; Price, AN; Choy, MK; Tybulewicz, VLJ; Optimised µMRI for Phenotyping the Tc1 Model of Down Syndrome. In: (Proceedings) Society for Magnetic Resonance in Medicine.

Fisher, EMC; Collins, T; Sheppard, O; Fratta, P; Devoy, A; (2013) Working with mice to help understand motor neuron disease. In: (Proceedings) National Hospital for Neurology and Neurosurgery. MND open day.

Fisher, EMC; Fratta, P; Joyce, P; Ricketts, T; Acevedo, A; Investigating specific transcriptomes in mouse models of amyotrophic lateral sclerosis. In: (Proceedings) EMBO Workshop on Intracellular RNA Localisation and localised translation.

Fisher, EMC; Greenfield, A; Cavanna, J; Brown, SDM; Microdissection of mammalian chromosomes. In: (Proceedings) International Chromosome meeting.

Fisher, EMC; Greenfield, A; Cavanna, J; Brown, SDM; Microdissection of mammalian chromosomes. In: (Proceedings) Mammalian Genetics Group/Mammalian Biochemical Genetics Group Conference.

Fisher, EMC; Greenfield, A; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) Genetical Society Symposium on Molecular Genetics of Animal Development.

Fisher, EMC; Greenfield, A; Cavanna, J; Brown, SDM; Microdissection of the mouse X chromosome. In: (Proceedings) Mammalian Genetics Group/Mammalian Biochemical Genetics Group conference.

Fisher, EMC; Greensmith, L; Investigating why dynein mutation ameliorates the SOD1 ALS phenotype and considerably extends lifespan. In: (Proceedings) 5th Annual Packard Center for ALS Research Symposium.

Fisher, EMC; Grimmett, W; Johnstone, K; McKie, J; O'Donnell, H; Pollock, P; Yulug, IG; Transferring subchromosomal fragments into mouse embryonic carcinoma and stem cells. In: (Proceedings) Mammalian Neurobiology Workshop.

Fisher, EMC; Grimmett, WJ; Johnstone, K; McKie, J; Pollock, PM; Strutt, P; Yulug, IG; A PCR approach to cloning genes from Chromosome 21. In: (Proceedings) 3rd International Workshop on Human Chromosome 21.

Fisher, EMC; Hafezparast, M; Ahmad-Annuar, A; Shah, P; Martin, JE; Models of motor neuron degeneration. In: (Proceedings) 13th International Symposium on ALS/MND.

Fisher, EMC; Johnstone, K; McKie, J; Scambler, PJ; Cell hybrids to isolate genes from human chromosome 21. In: (Proceedings) International Workshop on Chromosome 21..

Fisher, EMC; Joyce, P; Ricketts, T; Fratta, P; Greensmith, L; Acevedo, A; (2010) A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: (Proceedings) 21st International Symposium on ALS/MND.

Fisher, EMC; Martin, JE; (1997) Phenotypic and genotypic characterisation of feeble. In: Neuropathology and Applied Neuropathology.

Fisher, EMC; McGoldrick, P; Joyce, P; Acevedo, A; Greensmith, L; Investigating new mutant models of MND. In: (Proceedings) MRC Centre for Neuromuscular Diseases Annual Meeting.

Fisher, EMC; Page, DC; Characterising the distal short arm of the human Y chromosome. In: (Proceedings) Gordon Research Conference on Molecular Genetics.

Fisher, EMC; Ricketts, T; Fratta, P; Joyce, P; McGoldrick, P; Kent, R; Line, S; Characterisation of mouse TDP43 point mutations generated by chemical mutagenesis. In: (Proceedings) 6th Brain Research Conference, RNA-Binding proteins in neurological disease.

Fisher, EMC; Ricketts, T; Fratta, P; Joyce, P; McGoldrick, P; Kent, R; Line, S; Characterisation of mouse TDP43 point mutations generated by chemical mutagenesis. In: (Proceedings) American Society of Neuroscience Annual meeting.

Fisher, EMC; Ruparelia, A; Wiseman, F; Sheppard, O; Kuta, A; Tybulewicz, VLJ; Schiavo, G; Axonal transport in a panel of mice that model Down syndrome. In: (Proceedings) Queen Square student symposium, UCL Institute of Neurology.

Fisher, EMC; Sheppard, O; Plattner, F; Rubin, A; Slender, A; Tybulewicz, V; International Conference Jerome Lejeune. In: (Proceedings) International Conference Jerome Lejeune.

Fisher, EMC; Sheppard, O; Plattner, F; Rubin, A; Tybulewicz, V; Wiseman, F; Trisomy of DYRK1A and phosphorylation of tau in a mouse model of Down syndrome. In: (Proceedings) British Neuroscience Association Symposium 'Neurodevelopmental Disorders Across the Lifespan'.

Fisher, EMC; Watson-Scales, S; Lana-Elola, E; Tybulewicz, V; Using chromosome engineering to identify phenotype to genotype relationships in Down syndrome. In: (Proceedings) Mouse Neurological and Behavioural Forum 3.

Fisher, EMC; Wiseman, F; Sheppard, O; Barkus, C; Pettingill, P; Ruparelia, A; Slender, A; The role of trisomy of human chromosome 21 in the development of Alzheimer’s disease. In: (Proceedings) International Conference Jerome Lejeune.

Fisher, EMC; Wiseman, F; Sheppard, O; Barkus, C; Pettingill, P; Ruparelia, A; Slender, A; The role of trisomy of human chromosome 21 in the development of Alzheimer’s disease. In: (Proceedings) 12th Annual Alzherimer’s Research Trust Network Conference.

Fisher, EMC; Wiseman, F; Tybulewicz, V; (2013) Mouse models to understand Down syndrome and Alzheimer disease. In: (Proceedings) Dementia in Intellectual Disability, London Down Syndrome Interest Group meeting.

Fraham-Falkenbert, S; Johannsen, P; Law, I; Jennum, P; Isaacs, A; Brown, J; FReJA, ; changes in regional cerebral glucose metabolism in early symptomatic frontotemporal dementia linked to chromosome 3 (FTD3). In: (Proceedings) Danish Neurological Society meeting.

Fraham-Falkenbert, S; Johannsen, P; Law, I; Jennum, P; Isaacs, A; Brown, J; FReJA Collaboration, ; Changes in regional cerebral glucose metabolism in early symptomatic frontotemporal dementia linked to chromosome 3 (FTD3). In: (Proceedings) Danish Neurological Society meeting.

Fratta, P; Cortese, A; Plagnol, V; Brady, S; Lashley, T; Simone, R; de Silva, R; (2013) Alterations in RNA metabolism in sporadic inclusion body myositis. In: (Proceedings) Association of British Neurologists meeting.

Gade, A; Skibinski, G; Gydesen, S; FReJA-Consortium, ; Preclinical signs of impairment in persons at high risk of frontotemporal dementia related to chromosome 3 (FTD3): preliminary findings in neuropsychological tests. In: (Proceedings) 9th International conference on Alzheimer's disease and related disorders.

Gade, A; The-FReJA-Consortium, ; FTD3 neuropsychology. In: (Proceedings) 4th International Conference on Frontotemporal Dementia.

Gade, S; Brown, J; Chakrabarti, L; Johannsen, P; Gydesen, S; Association, FFRIJ; Chromosome 3 frontotemporal dementia (FTD-3): clinical course and neuropsychology. In: (Proceedings) International Neuropsychological Society.

Galante, M; Jani, H; Vanes, L; Daniel, H; Fisher, EMC; Tybulewicz, VLJ; Bliss, TVP; Analysis of cerebellar function in the Tc1 mouse model of Down syndrome. In: (Proceedings) Synaptic plasticity and repair.

Ghazi-Noori, S; Houghton, R; Fisher, EMC; Collinge, J; Asante, EA; Isaacs, AM; Phenotypic characterization of CHMP2B knockout mice. In: (Proceedings) 6th International Conference on Frontotemporal Dementias.

Ghazi-Noori, S; Stanczak-Mrozek, K; Smidak, M; Powell, C; O'Malley, C; Linehan, JM; Fisher, EMC; Phenotypic characterisation of Chmp2b knock out mice. In: (Proceedings) Society for Neuroscience meeting 2009.

Gray, IC; Nolan, PM; Peters, J; Strivens, M; Hough, T; Vizor, L; Glenister, P; New mouse models of human disease. In: (Proceedings) Asia Pacific HUGO meeting.

Grimmett, WJ; Johnstone, K; McKie, J; Strutt, P; Yulug, IG; Scambler, PJ; Fisher, EMC; Cloning genes from chromosome 21. In: European Journal of Human Genetics.

Haas, M; Fisher, E; Tybulewicz, VLJ; Guillemot, F; Cortical projection neuron morphology in the Tc1 and Ts1Rhr modele of Down syndrome. In: (Proceedings) 2nd Aneuploidy Workshop.

Haas, M; Fisher, EMC; Tybulewicz, VLJ; Guillemot, F; Cortical projection neuron morphology in the Tc1 and Ts1Rhr models of Down syndrome. In: (Proceedings) 2nd Aneuploidy Workshop.

Haas, M; Fisher, EMC; Tybulewicz, VLJ; Guillemot, F; Neurogenesis in the developing and adult Tc1 mouse, a model of human Down Syndrome. In: (Proceedings) First AnEUploidy Workshop.

Haas, M; Tybulewicz, VLJ; Fisher, EMC; Guillemot, F; Cortical development in the Tc1 mouse: a model of Down Syndrome. In: (Proceedings) ANS/AuPS Annual Meeting Sydney 2010.

Haas, M; Tybulewicz, VLJ; Fisher, EMC; Guillemot, F; Cortical neurogenesis in the Tc1 mouse model of Down syndrome. In: (Proceedings) Cortical Development.

Haas, M; Watson-Scales, S; Slender, A; Fisher, EMC; Tybulewicz, V; Guillemot, F; (2012) Understanding Down syndrome using the Tc1 mouse model. In: (Proceedings) Australian Neuroscience Society.

Haas, MA; Fisher, EMC; Tybulewicz, VLJ; Guillemot, F; (2010) Cortical projection neuron dendrite morphology in the Tc1 mouse model of Down Syndrome. In: INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. (pp. 706 - 706). PERGAMON-ELSEVIER SCIENCE LTD

Hafeparast, M; Nicholson, SJ; Witherden, AS; Bermingham, N; Ball, S; Peters, J; Rogers, DC; Loa (Legs at odd angles) a mouse model of motor neurone dysfuntion: mapping and progress towards isolation of the causal gene. In: (Proceedings) 14th International Mammalian Genome Society.

Hafezparast, M; Ahmad-Annuar, A; Lalli, G; Shima, DT; Schiavo, G; Ball, S; Peters, J; Legs at odd angles - a mutation in dynein that impairs the navigation of motor neurons. In: (Proceedings) Molecular Motors 61st Harden Conference.

Hafezparast, M; Ahmad-Annuar, A; Shah, P; Martin, JE; Fisher, EMC; Analysis of the cytoplasmic dynein heavy chain gene, which is mutated in the Loa mouse model of anterior horn cell degeneration. In: Amyotroph. Lateral Scler Other Motor Neuron Disord. (pp. 5 - 227).

Hafezparast, M; Ahmad-Annuar, A; Shah, P; Witherden, AS; Bowen, S; Ball, S; Peters, J; Physical and genetic mapping of Loa: a gene involved in motor neuron degeneration. In: (Proceedings) 16th International Mouse Genome Conference.

Hafezparast, M; Ahmad-Annuar, A; Witherden, A; Martin, JEM; Fisher, EMC; What have we learnt from Legs at odd angles - a mouse model of motor neuron degeneration? In: (Proceedings) 12th International symposium on ALS/MND.

Hafezparast, M; Hummerich, H; Fisher, EMC; Isolation of the legs at odd angles (Loa) gene in a nutant mouse with motor neuron degeneration. In: (Proceedings) UK Mouse genome sequencing meeting.

Hafezparast, M; Kieran, D; Bohnert, S; Dick, J; Martin, JE; Fisher, EMC; Schiavo, G; Neurodegeneration as a result of defective retrograde axonal transport. In: (Proceedings) Molecular aspects of ageing, and development, toxicology and neuro-immune communication.

Hafezparast, M; Nicholson, SJ; Witherden, AS; Bermingham, N; Ball, S; Peters, J; Rogers, DC; Loa (Legs at odd angles) a mouse model of motor neurone dysfunction: mapping and progress towrds isolation of the causal gene. In: (Proceedings) 2nd Annual Meeting of the International Behavioural and Neural Genetics Society.

Hafezparast, M; Ruhrberg, C; Ahmad-Annuar, A; Bowen, S; Achilli, F; Lalli, G; Ball, S; Mutations in dynein link motor neuron degeneration to defects in retrograde transport. In: (Proceedings) 17th International Mouse Genome Conference.

Hafezparast, M; Ruhrberg, C; Ahmad-Annuar, A; Bowen, S; Lalli, G; Preistley, JV; Takashi, T; Mutations in dynein link motor neuron degeneration to defects in retrograde transport. In: (Proceedings) Molecular Aspects of Neurodegenerative Diseases, Intra-neuronal transport and communication, Euro Conference Series, 2nd Meeting.

Hafezparast, M; Witherden, AS; Nicholson, SJ; Ahmad-Annuar, A; Bermingham, N; Arac, D; Rankin, J; A transcription map of distal chromosome 12 encompassing Loa: a gene involved in motor neuron degeneration. In: (Proceedings) 4th workshop on Mouse Molecular Neurogenetics.

Hatcher, JP; Rogers, DC; Nolan, P; Fisher, EMC; Martin, JE; Hunter, AJ; Development of SHIRPA to characterise the behavioural phenotype of transgenic and gene-targeted mice. In: (Proceedings) Behavioural phenotyping of mouse mutants.

Hernandez, D; Fisher, EMC; Tybulewicz, V; Modelling Down syndrome. In: (Proceedings) Mouse Molecular Genetics meeting.

Hernandez, D; Mee, P; Martin, J; Tybulewicz, V; Fisher, EMC; Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21. In: (Proceedings) Genetical Society Meeting.

Hernandez, D; Mee, P; Martin, J; Tybulewicz, V; Fisher, EMC; Transchromosomal mouse embyronic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21. In: (Proceedings) HUGO meeting.

Hernandez, D; Tybulewicz, V; Fisher, EMC; (1997) Modelling aspects of Down syndrome in mice. In: CYTOGENET CELL GENET. (pp. 29 - 29). KARGER

Hernandez, D; Tybulewicz, V; Fisher, EMC; (1994) Modelling Down syndrome in mouse. In: Genetics Research (Camb).

Hernandez, D; Tybulewicz, V; Fisher, EMC; Creating as panel of 'transgenomic' mouse embryonic stem cell lines that contain freely segregating portions of human chromosome 21. In: (Proceedings) Gordon Research Conference on Human Molecular Genetics.

Hernandez, D; Tybulewicz, V; Fisher, EMC; Modelling aspects of Down syndrome in mice. In: (Proceedings) International Conference on Down Syndrome and Chromosome 21.

Hernandez, D; Tybulewicz, V; Fisher, EMC; Modelling down syndrome in mice. In: (Proceedings) 3rd International Workshop on The Genetic Control of Vertebrate Development.

Hernandez, D; Tybulewicz, V; Fisher, EMC; Transgenic mouse model for Down syndrome. In: (Proceedings) Models for Development, Developmental Pathology Society Meeting.

Hernandez, D; Tybulewicz, VLJ; Fisher, EMC; Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21. In: (Proceedings) Mouse Molecular Genetics Meeting.

Hernandez, D; Tybulwicz, VLJ; Fisher, EMC; Creating as panel of 'transgenomic' mouse embryonic stem cell lines that contain freely segregating portions of human chromosome 21. In: (Proceedings) International Chromosome 21 Workshop.

Holm, IE; Englund, E; The-FReJA-Consortium, ; Ubiquitin positive inclusions in Frontotemporal Dementia linked to chromosome 3 (FTD-3). In: (Proceedings) 16th International Congress on Neuropathology.

Holm, IE; Englund, E; The-FReJA-Consortium, ; Ubiquitin positive inclusions in Frontotemporal Dementia linked to chromosome 3 (FTD-3). In: (Proceedings) 5th International Conference on Frontotemporal Dementia.

Holmes, H; Powell, N; Well, J; O'Callaghan, J; Colgan, N; Siow, B; Richardson, S; (2013) Tensor-based morphometry as a sensitive biomarker of Alzheimer’s disease neuropathology in a Tau transgenic mouse (Tg4510). In: (Proceedings) International Society for Magnetic Resonance in Medicine.

Holmes, H; Wells, J; O'Callaghan, J; Richardson, S; Siow, B; Powell, N; Da, M; (2012) Morphometric genomics: in vivo midro MRI for 3D structural imaging of transgenic mice. In: (Proceedings) International Society for Magnetic Resonance in Medicine British Chapter.

Holmes, H; Wells, J; O'Callaghan, J; Richardson, S; Siow, B; Powell, N; Ma, D; (2013) Morphometric Genomics: in vivo microMRI for 3D structural imaging of transgenic mice. In: (Proceedings) International Society for Magnetic Resonance in Medicine.

Holmes, H; Wells, J; Siow, B; O'Callaghan, J; Richardson, S; Oursellin, S; Powell, N; Optimisation of the inv vivo sequence for structural imaging of a mouse model of Alsheimer disease. In: (Proceedings) The International Society for Magnetic Resonance in Medicine.

Hough, T; Fisher, E; Cheeseman, M; Hunter, J; Brown, SDM; (2004) Characterization and genetics of a mouse model of hypophosphatasia. In: GENETICAL RESEARCH. (pp. 120 - 121). CAMBRIDGE UNIV PRESS

Hough, T; Fisher, EMC; Cheeseman, M; Hunter, AJ; Brown, SDM; Characterisation of mouse lines with abnormal levels of plasma alkaline phosphatase. In: (Proceedings) MRC Mammalian Genetics Unit Retreat.

Hough, T; Gray, IC; Nolan, PM; Peters, J; Fisher, EMC; Martin, J; Browne, M; Towards a mutant map of the mouse - new mutant models for bone, renal failure and blood lipids. In: (Proceedings) Mutagenesis Meeting.

Hough, T; Hunter, AJ; Nolan, PM; Tsipouri, V; Goldsworthy, M; Moir, L; Toye, A; Novel phenotypes identified by plasma biochemical screening in the mouse. In: (Proceedings) 15th International Mouse Genome conference.

Hough, T; Nolan, P; Tsipouri, V; Toye, A; Goldsworthy, M; Moir, L; Vizor, L; Mouse models of human metabolic disorders - characterisation of mutant lines with abnormal levels of plasma alkaline phosphatase. In: (Proceedings) 16th International Mouse Genome Conference.

Hough, T; Nolan, PM; Peters, J; Fisher, EMC; Martin, J; Browne, M; Rastan, S; Clinical biochemistry screens can complement behavioural screens in mutagenised mice. In: (Proceedings) 2nd Annual Meeting of International Behavioural and Neural Genetics Society.

Hoyle, J; Smith, DJ; Connolly, JAC; Fisher, EMC; (1995) Characterisation of the S4 gene, a member of a highly conserved gene family involved in ubiquitinated degradation of proteins. In: Genetics Research (Camb).

Hoyle, J; Smith, DJ; Fisher, EMC; Characterisation of the S4 gene in mouse and human. In: (Proceedings) 1st conference on the AAA family of ATPases.

Hoyle, J; Smith, DJ; Fisher, EMC; Characterisation of the S4 gene, a member of a highly conserved gene family involved in the ubiquitin protein degradation pathway. In: (Proceedings) Developmental Biology - Gordon Research Conference.

Hoyle, J; Wilkinson, D; Fisher, EMC; Expression of the mouse P26S4 gene, an ATPase regulatory subunit of the 26S proteosome. In: (Proceedings) Gordon Research Conference: Molecular Genetics.

Hunter, AJ; Hagan, JJ; Rogers, D; Nolan, P; Strivens, M; Peters, J; Brown, SDM; A comprehensive ENU mutagenesis programme has produced novel neurological and behavioural phenotypes. In: (Proceedings) 29th Annual Meeting of the Society for Neurosciences Meeting.

Hunter, AJ; Hagan, JJ; Rogers, D; Nolan, P; Strivens, M; Peters, J; Brown, SDM; A comprehensive ENU mutagenesis programme has produced novel neurological and behavioural phenotypes. In: (Proceedings) 27th Meeting of the European Teratology Society.

Hunter, J; Rogers, D; Hagan, J; Peters, J; Nolan, P; Vizor, L; Thornton, C; A comprehensive ENU mutagenesis programme for the mouse genome. In: (Proceedings) Physiological Society Meeting, Smithkline Beecham.

Isaacs, AM; Johannsen, P; Nielsen, JE; Holm, I; Fisher, E; Rossor, M; Gade, A; (2011) Frontotemporal dementia caused by CHMP2B mutations. In: Current Alzheimer Research. (pp. 246 - 251).

Isaacs, AM; Skibinski, G; Parkinson, NJ; Brown, JM; Nielsen, JE; Thusgaard, T; Brun, A; A mutation in CHMP2B is the likely cause of frontotemporal dementia in a large Danish kindred. In: (Proceedings) Society for Neuroscience Meeting.

Isaacs, AM; Skibinski, G; Parkinson, NJ; Brown, JM; Nielsen, JE; Thusgaard, T; Brun, A; Mutations in the endosomal gene CHMP2B in frontotemporal dementia. In: (Proceedings) 5th International Conference on Frontotemporal Dementia.

Isaacs, AM; Skibinski, G; Parkinson, NJ; Brown, JM; Nielsen, JE; Thusgaard, T; Brun, A; Mutations in the endosomal gene cHMP2B in frontotemporal dementia. In: (Proceedings) 5th International Conference on the frontotemporal dementias.

Isaacs, AM; Skibinski, G; Parkinson, NJ; Brown, JM; Nielsen, JE; Thusgaard, T; Brun, A; A mutation in the endosomal gene CHMP2B in frontotemporal dementia. In: (Proceedings) Society for Neuroscience.

Johannsen, P; Eskildesen, S; Neilsen, J; Fisher, EMC; Zeidler, D; Rodell, A; Ostergaard, L; (2006) Functional and structural imaging in FTD3. In: Alzheimer's & Dementia Journal. (pp. S15 - S15).

Johannsen, P; Eskildsen, SF; Nielsen, J; Fisher, EMC; Zeidler, D; Rodell, A; Ostergaard, L; (2006) Brain cortical thickness in a FTD3 patient and mutation carriers. In: The Alzheimer's Society Journal: Alzheimer's & Dementia. (pp. S15 - S15). Elsevier

Johannsen, P; Fraham-Falkenberg, S; Law, I; Jennum, P; Isaacs, A; Brown, J; Nielsen, JE; Changes in cerebral glucose metabolism in early symptomatic frontotemporal dementia linked to chromosome 3 (FTD-3). In: (Proceedings) European Neurology Conference.

Johannsen, P; Frahm-Falkenberg, S; Law, I; Jennum, P; Isaacs, A; Brown, J; Nielsen, JE; (2011) CHANGES IN CEREBRAL GLUCOSE METABOLISM IN EARLY SYMPTOMATIC FRONTOTEMPORAL DEMENTIA LINKED TO CHROMOSOME 3 (FTD-3). In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 75 - 75). WILEY-BLACKWELL

Johannsen, P; Gade, A; Brown, J; Chakrabarti, L; Ghedde, A; Gydesen, S; Sorensen, SA; (2002) Extensive cerebral blood flow deficits in chromosome 3 frontotemporal dementia. In: Neurobiology of Ageing. (pp. S59 - S60).

Johannsen, P; Gade, A; Brown, J; Ghakrabarti, K; Gjedde, A; Gydesen, S; Sorensen, SA; Extensive cerebral blood flow deficits in chromosome 2 frontotemporal dementia. In: (Proceedings) 10th International Congress Psychogeriatric Association Meeting.

Johannsen, P; Gade, A; Brown, J; Gydesen, S; Chakrabarti, L; Thusgaard, T; Fisher, EMC; Chromosome-3 frontotemporal dementia (FTD3) with global cerebral blood flow decreases. In: (Proceedings) Annual Meeting Danish Neurological Society.

Johannsen, P; Holm, I; Eskildsen, SF; Rodell, A; Isaacs, AM; Gade, A; Nielsen, J; New imaging and neuropathology findings in FRD-3 patients and mutation carriers. In: (Proceedings) 5th International Conference on Frontotemporal Dementia.

Johannsen, P; Roos, P; Law, I; Frahm-Falkenberg, S; Isaacs, A; Brown, J; Nielsen, JE; (2012) Changes in Cerebral Glucose Metabolism in Early Symptomatic Frontotemporal Dementia Linked to Chromosome 3 (FTD-3). In: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. (pp. 130 - 131).

Johannsen, P; The-FReJA-Consortium, ; FTD3 brain imaging. In: (Proceedings) 4th International Conference on Frontotemporal Dementia.

Joyce, P; Fratta, P; Phatac, V; McGoldrick, P; Greensmith, L; Fisher, EMC; Acevedo-Arozena, A; A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: (Proceedings) UK Neuromuscular Translational Research conference.

Joyce, P; Fratta, P; Phatac, V; McGoldrick, P; Greensmith, L; Fisher, EMC; Acevedo-Arozena, A; A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: (Proceedings) UK Neuromuscular Translational Research conference.

Joyce, P; Fratta, P; Phatak, V; McGoldrick, P; Greensmith, L; Fisher, EMC; Acevedo-Arozena, A; A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: (Proceedings) American Society of Neuroscience Annual meeting.

Joyce, P; Fratta, P; Phatak, V; McGoldrick, R; Greensmith, L; Fisher, EMC; Acevedo-Arozena, A; (2011) A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene. In: NEUROMUSCULAR DISORDERS. (pp. S6 - S6). PERGAMON-ELSEVIER SCIENCE LTD

Katsanis, N; Fisher, EMC; Adding to the transcription map of HSA21. In: (Proceedings) 7th International Chromosome 21 Workshop.

Katsanis, N; Fisher, EMC; Identification and mapping single copy expressed sequences on human chromosome 21. In: (Proceedings) 6th International Workshop on Human Chromosome 21.

Katsanis, N; Humphreys, C; Sarner, S; de-Belleroche, J; Collinge, J; Fisher, EMC; An improved protocol for the analysis of Sod1 gene mutations: screening of UK ALS families. In: (Proceedings) 5th International Symposium on ALS and other MND.

Katsanis, N; Yaspo, ML; Fisher, EMC; (1995) cDNA selection from human chromosome 21. In: Genetics Research (Camb).

Katsanis, N; Yaspo, ML; Fisher, EMC; Enrichment of the expressed sequence map of human chromosome 21. In: European Journal of Human Genetics.

Katsanis, N; Yulug, I; Yaspo, ML; Fisher, EMC; Analysis of expressed sequences from human chromosome 21. In: (Proceedings) Gordon Research Conference on Human Molecular Genetics.

Katsanis, N; Yulug, IG; Yaspo, ML; Hernandez, D; Fisher, EMC; cDNA selection and isolation from human chromosome 21. In: (Proceedings) 5th International Workshop on Human Chromosome 21.

Kieran, D; Hafezparast, M; Bohnert, S; Dick, J; Martin, J; Schiavo, G; Fisher, EMC; Disrupted axonal transport in SOD1G93A transgenics is restored by mutant dynein, so significantly extending lifespan. In: (Proceedings) 15th International ALS symposium.