Browse by UCL people
Group by: Type | Date
Number of items: 43.
2024
Altmann, A;
Aksman, LM;
Oxtoby, NP;
Young, AL;
Alexander, DC;
Barkhof, F;
Shoai, M;
... Schott, JM; + view all
(2024)
Towards cascading genetic risk in Alzheimer’s disease.
Brain
, 147
(8)
pp. 2680-2690.
10.1093/brain/awae176.
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Mastenbroek, SE;
Vogel, JW;
Collij, LE;
Serrano, GE;
Tremblay, C;
Young, AL;
Arce, RA;
... Hansson, O; + view all
(2024)
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology.
Nature Communications
, 15
, Article 5133. 10.1038/s41467-024-49402-x.
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Prosser, Lloyd;
Sudre, Carole H;
Oxtoby, Neil P;
Young, Alexandra L;
Malone, Ian B;
Manning, Emily N;
Pemberton, Hugh;
... Barnes, Josephine; + view all
(2024)
Biomarker pathway heterogeneity of amyloid-positive individuals.
Alzheimer's & Dementia
, 20
(12)
pp. 8503-8515.
10.1002/alz.14287.
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Sone, Daichi;
Young, Alexandra;
Shinagawa, Shunichiro;
Tsugawa, Sakiko;
Iwata, Yusuke;
Tarumi, Ryosuke;
Ogyu, Kamiyu;
... Nakajima, Shinichiro; + view all
(2024)
Disease Progression Patterns of Brain Morphology in Schizophrenia: More Progressed Stages in Treatment Resistance.
Schizophrenia Bulletin
, 50
(2)
pp. 393-402.
10.1093/schbul/sbad164.
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Totzek, Jana F;
Chakravarty, M Mallar;
Joober, Ridha;
Malla, Ashok;
Shah, Jai L;
Raucher-Chéné, Delphine;
Young, Alexandra L;
... Lavigne, Katie M; + view all
(2024)
Longitudinal inference of multiscale markers in psychosis: from hippocampal centrality to functional outcome.
Molecular Psychiatry
, 29
pp. 2929-2938.
10.1038/s41380-024-02549-x.
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Yong, KXX;
Petzold, A;
Foster, P;
Young, A;
Bell, S;
Bai, Y;
Leff, AP;
... Greenwood, JA; + view all
(2024)
The Graded Incomplete Letters Test (GILT): a rapid test to detect cortical visual loss, with UK Biobank implementation.
Behavior Research Methods
10.3758/s13428-024-02448-7.
(In press).
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Young, Alexandra L;
Oxtoby, Neil P;
Garbarino, Sara;
Fox, Nick C;
Barkhof, Frederik;
Schott, Jonathan M;
Alexander, Daniel C;
(2024)
Data-driven modelling of neurodegenerative disease progression: thinking outside the black box.
Nature Reviews Neuroscience
, 25
pp. 111-130.
10.1038/s41583-023-00779-6.
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2023
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Aksman, Leon M;
Oxtoby, Neil P;
Scelsi, Marzia A;
Wijeratne, Peter A;
Young, Alexandra L;
Lopes Alves, Isadora;
Collij, Lyduine E;
... The, ADNI; + view all
(2023)
A data-driven study of Alzheimer's disease related amyloid and tau pathology progression.
Brain
10.1093/brain/awad232.
(In press).
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Rangelov, Bojidar;
Young, Alexandra;
Lilaonitkul, Watjana;
Aslani, Shahab;
Taylor, Paul;
Guðmundsson, Eyjólfur;
Yang, Qianye;
... Тhe NCCID Collaborative; + view all
(2023)
Delineating COVID-19 subgroups using routine clinical data identifies distinct in-hospital outcomes.
Scientific Reports
, 13
, Article 9986. 10.1038/s41598-023-32469-9.
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Scotton, William J;
Shand, Cameron;
Todd, Emily;
Bocchetta, Martina;
Cash, David M;
VandeVrede, Lawren;
Heuer, Hilary;
... Wijeratne, Peter A; + view all
(2023)
Uncovering spatiotemporal patterns of atrophy in progressive supranuclear palsy using unsupervised machine learning.
Brain Communications
, 5
(2)
, Article fcad048. 10.1093/braincomms/fcad048.
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Xiao, Fenglai;
Caciagli, Lorenzo;
Wandschneider, Britta;
Sone, Daichi;
Young, Alexandra L;
Vos, Sjoerd B;
Winston, Gavin P;
... Koepp, Matthias J; + view all
(2023)
Identification of different MRI atrophy progression trajectories in epilepsy by subtype and stage inference.
Brain
10.1093/brain/awad284.
(In press).
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Young, AL;
Aksman, LM;
Alexander, DC;
Wijeratne, PA;
(2023)
Subtype and Stage Inference with Timescales.
In: Frangi, A and DeBruijne, M and Wassermann, D and Navab, N, (eds.)
International Conference on Information Processing in Medical Imaging.
(pp. pp. 15-26).
Springer Nature
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Young, Alexandra L;
Vogel, Jacob W;
Robinson, John L;
McMillan, Corey T;
Ossenkoppele, Rik;
Wolk, David A;
Irwin, David J;
... Hansson, Oskar; + view all
(2023)
Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies.
Brain
, 146
(7)
pp. 2975-2988.
10.1093/brain/awad145.
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2021
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Aksman, LM;
Wijeratne, PA;
Oxtoby, NP;
Eshaghi, A;
Shand, C;
Altmann, A;
Alexander, DC;
(2021)
pySuStaIn: A Python implementation of the Subtype and Stage Inference algorithm.
SoftwareX
, 16
, Article 100811. 10.1016/j.softx.2021.100811.
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Archetti, D;
Young, AL;
Oxtoby, NP;
Ferreira, D;
Mårtensson, G;
Westman, E;
Alexander, DC;
... for Alzheimer’s Disease Neuroimaging Initiative and EuroPOND Con; + view all
(2021)
Inter-Cohort Validation of SuStaIn Model for Alzheimer's Disease.
Frontiers in Big Data
, 4
, Article 661110. 10.3389/fdata.2021.661110.
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Eshaghi, A;
Young, A;
Wijeratne, PA;
Prados, F;
Arnold, DL;
Narayanan, S;
Guttmann, CRG;
... Ciccarelli, O; + view all
(2021)
Identifying multiple sclerosis subtypes using unsupervised machine learning and MRI data.
Nature Communications
, 12
, Article 2078. 10.1038/s41467-021-22265-2.
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Fiford, CM;
Sudre, CH;
Young, AL;
Macdougall, A;
Nicholas, J;
Manning, EN;
Malone, IB;
... Alzheimer’s Disease Neuroimaging Initiative, .; + view all
(2021)
Presumed small vessel disease, imaging and cognition markers in the Alzheimer's Disease Neuroimaging Initiative.
Brain Communications
, 3
(4)
, Article fcab226. 10.1093/braincomms/fcab226.
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Oxtoby, N;
Leyland, L;
Aksman, L;
Thomas, G;
Bunting, E;
Wijeratne, P;
Young, A;
... Weil, R; + view all
(2021)
Sequence of clinical and neurodegeneration events in Parkinson’s disease progression.
Brain
, Article awaa461. 10.1093/brain/awaa461.
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Vogel, JW;
Young, AL;
Oxtoby, NP;
Smith, R;
Ossenkoppele, R;
Strandberg, OT;
La Joie, R;
... Hansson, O; + view all
(2021)
Four distinct trajectories of tau deposition identified in Alzheimer's disease.
Nature Medicine
, 27
pp. 871-881.
10.1038/s41591-021-01309-6.
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Young, AL;
Vogel, JW;
Aksman, LM;
Wijeratne, PA;
Eshaghi, A;
Oxtoby, NP;
Williams, SCR;
... Alzheimer’s Disease Neuroimaging Initiative; + view all
(2021)
Ordinal SuStaIn: Subtype and Stage Inference for Clinical Scores, Visual Ratings, and Other Ordinal Data.
Frontiers in Artificial Intelligence
, 4
, Article 613261. 10.3389/frai.2021.613261.
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Young, AL;
Bocchetta, M;
Russell, LL;
Convery, RS;
Peakman, G;
Todd, E;
Cash, DM;
... Genetic FTD Initiative (GENFI); + view all
(2021)
Characterizing the Clinical Features and Atrophy Patterns of MAPT-Related Frontotemporal Dementia With Disease Progression Modeling.
Neurology
10.1212/WNL.0000000000012410.
(In press).
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2020
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Firth, NC;
Primativo, S;
Brotherhood, E;
Young, AL;
Yong, KXX;
Crutch, SJ;
Alexander, DC;
(2020)
Sequences of cognitive decline in typical Alzheimer's disease and posterior cortical atrophy estimated using a novel event‐based model of disease progression.
Alzheimer's & Dementia
, 16
(7)
pp. 965-973.
10.1002/alz.12083.
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Gabel, MC;
Broad, RJ;
Young, AL;
Abrahams, S;
Bastin, ME;
Menke, RAL;
Al-Chalabi, A;
... Cercignani, M; + view all
(2020)
Evolution of white matter damage in amyotrophic lateral sclerosis.
Annals of Clinical and Translational Neurology
, 7
(5)
pp. 722-732.
10.1002/acn3.51035.
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Marinescu, RV;
Oxtoby, NP;
Young, AL;
Bron, EE;
Toga, AW;
Weiner, MW;
Barkhof, F;
... Alexander, DC; + view all
(2020)
The Alzheimer's Disease Prediction Of Longitudinal Evolution (TADPOLE) Challenge: Results after 1 Year Follow-up.
ArXiv
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Pascuzzo, R;
Oxtoby, NP;
Young, AL;
Blevins, J;
Castelli, G;
Garbarino, S;
Cohen, ML;
... Bizzi, A; + view all
(2020)
Prion propagation estimated from brain diffusion MRI is subtype dependent in sporadic Creutzfeldt-Jakob disease.
Acta Neuropathologica
10.1007/s00401-020-02168-0.
(In press).
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Rangelov, BA;
Young, AL;
Jacob, J;
Cahn, AP;
Lee, S;
Wilson, FJ;
Hawkes, DJ;
(2020)
Thoracic Imaging at Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review.
International Journal of Chronic Obstructive Pulmonary Disease
, 2020
(15)
pp. 1751-1787.
10.2147/copd.s250746.
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2019
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Archetti, D;
Ingala, S;
Venkatraghavan, V;
Wottschel, V;
Young, AL;
Bellio, M;
Bron, EE;
... for EuroPOND Consortium, .; + view all
(2019)
Multi-study validation of data-driven disease progression models to characterize evolution of biomarkers in Alzheimer's disease.
Neuroimage Clinical
, 24
, Article 101954. 10.1016/j.nicl.2019.101954.
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Firth, NC;
Primativo, S;
Marinescu, R-V;
Shakespeare, TJ;
Suarez-Gonzalez, A;
Lehmann, M;
Carton, A;
... Crutch, SJ; + view all
(2019)
Longitudinal neuroanatomical and cognitive progression of posterior cortical atrophy.
Brain
, 142
(7)
pp. 2082-2095.
10.1093/brain/awz136.
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Marinescu, RV;
Eshaghi, A;
Lorenzi, M;
Young, AL;
Oxtoby, NP;
Garbarino, S;
Crutch, SJ;
... Alzheimer's Disease Neuroimaging Initiative, .; + view all
(2019)
DIVE: A spatiotemporal progression model of brain pathology in neurodegenerative disorders.
NeuroImage
, 192
pp. 166-177.
10.1016/j.neuroimage.2019.02.053.
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Marinescu, RV;
Lorenzi, M;
Blumberg, SB;
Young, AL;
Planell-Morell, P;
Oxtoby, NP;
Eshaghi, A;
... Alexander, DC; + view all
(2019)
Disease Knowledge Transfer Across Neurodegenerative Diseases.
In:
Medical Image Computing and Computer Assisted Intervention – MICCAI 2019.
(pp. pp. 860-868).
Springer Nature: Cham, Switzerland.
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Marinescu, RV;
Oxtoby, NP;
Young, AL;
Bron, EE;
Toga, AW;
Weiner, MW;
Barkhof, F;
... Alexander, DC; + view all
(2019)
TADPOLE Challenge: Accurate Alzheimer’s Disease Prediction Through Crowdsourced Forecasting of Future Data.
In: Rekik, I and Adeli, E and Park, SH, (eds.)
Predictive Intelligence in Medicine.
(pp. pp. 1-10).
Springer,: Cham, Switzerland.
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Slator, P;
Hutter, J;
Marinescu, R;
Palombo, M;
Young, A;
Jackson, L;
Ho, A;
... Alexander, D; + view all
(2019)
InSpect: INtegrated SPECTral Component Estimation and Mapping for Multi-Contrast Microstructural MRI.
In: Chung, A and Gee, J and Yushkevich, P and Bao, S, (eds.)
Proceedings of Information Processing in Medical Imaging - IPMI 2019.
(pp. pp. 755-766).
Springer: Cham.
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Young, AL;
Bragman, FJS;
Rangelov, B;
Han, M;
Galbán, CJ;
Lynch, DA;
Hawkes, DJ;
... COPDGene Investigators, .; + view all
(2019)
Disease Progression Modelling in Chronic Obstructive Pulmonary Disease (COPD).
American Journal of Respiratory and Critical Care Medicine
10.1164/rccm.201908-1600OC.
(In press).
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2018
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Eshaghi, A;
Marinescu, RV;
Young, AL;
Firth, NC;
Prados Carrasco, F;
Cardoso, MJ;
Tur Gomez, C;
... MAGNIMS Study Group, .; + view all
(2018)
Progression of regional grey matter atrophy in multiple sclerosis.
Brain
, 141
(6)
pp. 1665-1677.
10.1093/brain/awy088.
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Firth, N;
Oxtoby, N;
Primativo, S;
Brotherhood, E;
Young, A;
Yong, KXX;
Crutch, S;
(2018)
Non-Parametric Mixture Modelling and its Application to Disease Progression Modelling.
BioRxiv
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Georgiadis, K;
Young, AL;
Hütel, M;
Razi, A;
Semedo, C;
Schott, J;
Ourselin, S;
... Modat, M; + view all
(2018)
Computational modelling of pathogenic protein behaviour-governing mechanisms in the brain.
In: Frangi, AF and Schnabel, JA and Davatzikos, C and Alberola-López, C and Fichtinger, G, (eds.)
Medical Image Computing and Computer Assisted Intervention – MICCAI 2018, 21st International Conference: Proceedings, Part III.
(pp. pp. 532-539).
Springer: Cham, Switzerland.
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Marinescu, RV;
Oxtoby, NP;
Young, AL;
Bron, EE;
Toga, AW;
Weiner, MW;
Barkhof, F;
... Consortium, TE; + view all
(2018)
TADPOLE Challenge: Prediction of Longitudinal Evolution in Alzheimer's Disease.
arXiv.org
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Wijeratne, PA;
Young, AL;
Oxtoby, NP;
Marinescu, RV;
Firth, NC;
Johnson, EB;
Mohan, A;
... Alexander, DC; + view all
(2018)
An image-based model of brain volume biomarker changes in Huntington's disease.
Annals of Clinical and Translational Neurology
, 5
(5)
pp. 570-582.
10.1002/acn3.558.
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Young, AL;
Marinescu, RV;
Oxtoby, NP;
Bocchetta, M;
Yong, K;
Firth, NC;
Cash, DM;
... Alzheimer’s Disease Neuroimaging Initiative (ADNI), .; + view all
(2018)
Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference.
Nature Communications
, 9
, Article 4273. 10.1038/s41467-018-05892-0.
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2017
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Marinescu, RV;
Eshaghi, A;
Lorenzi, M;
Young, AL;
Oxtoby, NP;
Garbarino, S;
Shakespeare, TJ;
... Alexander, DC; + view all
(2017)
A vertex clustering model for disease progression: Application to cortical thickness images.
In: Hutchison, David and Kanade, Takeo and Kittler, Josef and Kleinberg, Jon M. and Mattern, Friedemann and Mitchell, John C. and Naor, Moni and Rangan, C. Pandu and Steffen, Bernhard and Terzopoulos, Demetri and Tygar, Doug and Weikum, Gerhard, (eds.)
Information Processing in Medical Imaging. IPMI 2017. Lecture Notes in Computer Science.
(pp. pp. 134-145).
Springer: Cham, Switzerland.
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Young, AL;
(2017)
Modelling progression and heterogeneity in Alzheimer's disease.
Doctoral thesis , UCL (University College London).
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2015
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Young, AL;
Oxtoby, NP;
Ourselin, S;
Schott, JM;
Alexander, DC;
(2015)
A simulation system for biomarker evolution in neurodegenerative disease.
Medical Image Analysis
, 26
(1)
pp. 47-56.
10.1016/j.media.2015.07.004.
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2014
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Young, AL;
Oxtoby, NP;
Daga, P;
Cash, DM;
Fox, NC;
Ourselin, S;
Schott, JM;
... on behalf of the Alzheimer’s Disease Neuroimaging Initiative; + view all
(2014)
A data-driven model of biomarker changes in sporadic Alzheimer's disease.
Brain
, 137
(9)
pp. 2564-2577.
10.1093/brain/awu176.
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