Browse by UCL people
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Number of items: 31.
Article
Abbosh, Christopher;
Frankell, Alexander M;
Harrison, Thomas;
Kisistok, Judit;
Garnett, Aaron;
Johnson, Laura;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2023)
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Nature
, 616
(7957)
pp. 553-562.
10.1038/s41586-023-05776-4.
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Abbosh, C;
Birkbak, NJ;
Wilson, GA;
Jamal-Hanjani, M;
Constantin, T;
Salari, R;
Le Quesne, J;
... Dessimoz, C; + view all
(2017)
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
Nature
, 545
pp. 446-451.
10.1038/nature22364.
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AbdulJabbar, K;
Raza, SEA;
Rosenthal, R;
Jamal-Hanjani, M;
Veeriah, S;
Akarca, A;
Lund, T;
... Yuan, Y; + view all
(2020)
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma.
Nature Medicine
, 26
pp. 1054-1062.
10.1038/s41591-020-0900-x.
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Al Bakir, Maise;
Huebner, Ariana;
Martínez-Ruiz, Carlos;
Grigoriadis, Kristiana;
Watkins, Thomas BK;
Pich, Oriol;
Moore, David A;
... Swanton, Charles; + view all
(2023)
The evolution of non-small cell lung cancer metastases in TRACERx.
Nature
10.1038/s41586-023-05729-x.
(In press).
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Au, L;
Hatipoglu, E;
Robert de Massy, M;
Litchfield, K;
Beattie, G;
Rowan, A;
Schnidrig, D;
... TRACERx Renal Consortium; + view all
(2021)
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.
Cancer Cell
, 39
pp. 1497-1518.
10.1016/j.ccell.2021.10.001.
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Balestrini, S;
Koepp, MJ;
Gandhi, S;
Rickman, HM;
Yen Shin, G;
Houlihan, CF;
Anders-Cannon, J;
... Sisodiya, SM; + view all
(2021)
Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy.
Epilepsy & Behavior
, 115
, Article 107602. 10.1016/j.yebeh.2020.107602.
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Bentham, R;
Litchfield, K;
Watkins, TBK;
Lim, EL;
Rosenthal, R;
Martinez-Ruiz, C;
Hiley, CT;
... McGranahan, N; + view all
(2021)
Using DNA sequencing data to quantify T cell fraction and therapy response.
Nature
, 597
pp. 555-560.
10.1038/s41586-021-03894-5.
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Biswas, Dhruva;
Liu, Yun-Hsin;
Herrero, Javier;
Wu, Yin;
Moore, David A;
Karasaki, Takahiro;
Grigoriadis, Kristiana;
... Swanton, Charles; + view all
(2025)
Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma
adenocarcinoma.
Nature Cancer
, 6
pp. 86-101.
10.1038/s43018-024-00883-1.
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Biswas, D;
Birkbak, NJ;
Rosenthal, R;
Hiley, CT;
Lim, EL;
Papp, K;
Boeing, S;
... TRACERx Consortium; + view all
(2019)
A clonal expression biomarker associates with lung cancer mortality.
Nature Medicine
, 25
pp. 1540-1548.
10.1038/s41591-019-0595-z.
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Black, James RM;
Bartha, Gabor;
Abbott, Charles W;
Boyle, Sean M;
Karasaki, Takahiro;
Li, Bailiang;
Chen, Rui;
... Swanton, Charles; + view all
(2025)
Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma.
Nature Medicine
, 31
pp. 70-76.
10.1038/s41591-024-03216-y.
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Cameron, AJM;
Veeriah, S;
Marshall, JJT;
Murray, ER;
Larijani, B;
Parker, PJ;
(2017)
Uncoupling TORC2 from AGC kinases inhibits tumour growth.
Oncotarget
, 8
(49)
pp. 84685-84696.
10.18632/oncotarget.20086.
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Chemi, F;
Rothwell, DG;
McGranahan, N;
Gulati, S;
Abbosh, C;
Pearce, SP;
Zhou, C;
... TRACERx Consortium, .; + view all
(2019)
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.
Nature Medicine
, 25
pp. 1534-1539.
10.1038/s41591-019-0593-1.
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Enfield, Katey SS;
Colliver, Emma;
Lee, Claudia SY;
Magness, Alastair;
Moore, David A;
Sivakumar, Monica;
Grigoriadis, Kristiana;
... Angelova, Mihaela; + view all
(2024)
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer.
Cancer Discovery
, 14
(1)
pp. 1-30.
10.1158/2159-8290.CD-23-1380.
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Frankell, Alexander M;
Dietzen, Michelle;
Al Bakir, Maise;
Lim, Emilia L;
Karasaki, Takahiro;
Ward, Sophia;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2024)
The evolution of lung cancer and impact of subclonal selection in TRACERx (vol 616, pg 525, 2023).
[Corrigendum].
Nature
, 631
, Article E15. 10.1038/s41586-024-07738-w.
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Frankell, AM;
Dietzen, M;
Al Bakir, M;
Lim, EL;
Karasaki, T;
Ward, S;
Veeriah, S;
... Gilbert, K; + view all
(2023)
The evolution of lung cancer and impact of subclonal selection in TRACERx.
Nature
, 616
pp. 525-533.
10.1038/s41586-023-05783-5.
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Ghorani, E;
Reading, JL;
Henry, JY;
Massy, MRD;
Rosenthal, R;
Turati, V;
Joshi, K;
... Quezada, SA; + view all
(2020)
The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
Nature Cancer
, 1
(5)
pp. 546-561.
10.1038/s43018-020-0066-y.
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Hobor, S;
Al Bakir, M;
Hiley, CT;
Skrzypski, M;
Frankell, AM;
Bakker, B;
Watkins, TBK;
... Clipson, A; + view all
(2024)
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling.
Nature Communications
, 15
, Article 4871. 10.1038/s41467-024-47606-9.
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Hynds, Robert E;
Huebner, Ariana;
Pearce, David R;
Hil, Mark S;
Akarca, Ayse U;
Moore, David A;
Ward, Sophia;
... Swanton, Charles; + view all
(2024)
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models.
Nature Communications
, 15
, Article 4653. 10.1038/s41467-024-47547-3.
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Hynds, RE;
Ben Aissa, A;
Gowers, KHC;
Watkins, TBK;
Bosshard-Carter, L;
Rowan, AJ;
Veeriah, S;
... Janes, SM; + view all
(2018)
Expansion of airway basal epithelial cells from primary human non-small cell lung cancer tumors.
International Journal of Cancer
, 143
(1)
pp. 160-166.
10.1002/ijc.31383.
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Jamal-Hanjani, M;
Wilson, GA;
McGranahan, N;
Birkbak, NJ;
Watkins, TBK;
Veeriah, S;
Shafi, S;
... Swanton, C; + view all
(2017)
Tracking the Evolution of Non-Small-Cell Lung Cancer.
New England Journal of Medicine
, 376
(22)
pp. 2109-2121.
10.1056/NEJMoa1616288.
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Joshi, K;
Robert de Massy, M;
Ismail, M;
Reading, JL;
Uddin, I;
Woolston, A;
Hatipoglu, E;
... Chain, B; + view all
(2019)
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Nature Medicine
, 25
pp. 1549-1559.
10.1038/s41591-019-0592-2.
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Litchfield, K;
Stanislaw, S;
Spain, L;
Gallegos, LL;
Rowan, A;
Schnidrig, D;
Rosenbaum, H;
... Turajlic, S; + view all
(2020)
Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue.
Cell Reports
, 31
(5)
p. 107550.
10.1016/j.celrep.2020.107550.
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López, S;
Lim, EL;
Horswell, S;
Haase, K;
Huebner, A;
Dietzen, M;
Mourikis, TP;
... McGranahan, N; + view all
(2020)
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
Nature Genetics
, 52
(3)
pp. 283-293.
10.1038/s41588-020-0584-7.
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McGranahan, N;
Rosenthal, R;
Hiley, CT;
Rowan, AJ;
Watkins, TBK;
Wilson, GA;
Birkbak, NJ;
... Swanton, C; + view all
(2017)
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.
Cell
10.1016/j.cell.2017.10.001.
(In press).
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Nageswaran, Gayathri;
Byrne, Suzanne;
Veeriah, Selvaraju;
Chain, Benny;
(2022)
The Intra-Tumoral T Cell Receptor Repertoire: Steps Towards a Useful Clinical Biomarker.
Methods in Molecular Biology
, 2574
pp. 135-158.
10.1007/978-1-0716-2712-9_6.
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Ng, Kevin W;
Boumelha, Jesse;
Enfield, Katey SS;
Almagro, Jorge;
Cha, Hongui;
Pich, Oriol;
Karasaki, Takahiro;
... Kassiotis, George; + view all
(2023)
RETRACTED ARTICLE: Antibodies against endogenous retroviruses promote lung cancer immunotherapy.
Nature
, 616
pp. 563-573.
10.1038/s41586-023-05771-9.
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Pan, Xiaoxi;
AbdulJabbar, Khalid;
Coelho-Lima, Jose;
Grapa, Anca-Ioana;
Zhang, Hanyun;
Cheung, Alvin Ho Kwan;
Baena, Juvenal;
... Moore, David A; + view all
(2024)
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma.
Nature Cancer
10.1038/s43018-023-00694-w.
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Puttick, Clare;
Jones, Thomas P;
Leung, Michelle M;
Galvez-Cancino, Felipe;
Liu, Jiali;
Varas-Godoy, Manuel;
Rowan, Andrew;
... Mcgranahan, Nicholas; + view all
(2024)
MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution.
Nature Genetics
, 56
(10)
pp. 2121-2131.
10.1038/s41588-024-01883-8.
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Rosenthal, R;
Cadieux, EL;
Salgado, R;
Bakir, MA;
Moore, DA;
Hiley, CT;
Lund, T;
... TRACERx consortium; + view all
(2019)
Neoantigen-directed immune escape in lung cancer evolution.
Nature
10.1038/s41586-019-1032-7.
(In press).
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Zhang, Hanyun;
AbdulJabbar, Khalid;
Moore, David A;
Akarca, Ayse;
Enfield, Katey SS;
Jamal-Hanjani, Mariam;
Raza, Shan E Ahmed;
... Yuan, Yinyin; + view all
(2023)
Spatial Positioning of Immune Hotspots Reflects the Interplay between B and T Cells in Lung Squamous Cell Carcinoma.
Cancer Research
, 83
(9)
pp. 1410-1425.
10.1158/0008-5472.CAN-22-2589.
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Proceedings paper
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Raza, SEA;
AbdulJabbar, K;
Jamal-Hanjani, M;
Veeriah, S;
Le Quesne, J;
Swanton, C;
Yuan, Y;
(2019)
Deconvolving Convolutional Neural Network for Cell Detection.
In:
2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019).
(pp. pp. 891-894).
IEEE: Venice, Italy,.
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