Browse by UCL people
Group by: Type | Date
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Number of items: 28.
Article
Anandagoda, N;
Roberts, L;
Willis, JCD;
Sarathchandra, P;
Xiao, F;
Jackson, I;
Hertweck, A;
... Lord, GM; + view all
(2020)
Dominant regulation of long-term allograft survival is mediated by microRNA-142.
American Journal of Transplantation
, 20
(10)
pp. 2715-2727.
10.1111/ajt.15907.
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Anandagoda, N;
Willis, JC;
Hertweck, A;
Roberts, LB;
Jackson, I;
Gökmen, MR;
Jenner, RG;
... Lord, GM; + view all
(2019)
microRNA-142-mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance.
Journal of Clinical Investigation
10.1172/JCI124725.
(In press).
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Beltran, M;
Tavares, M;
Justin, N;
Khandelwal, G;
Ambrose, J;
Foster, BM;
Worlock, KB;
... Jenner, RG; + view all
(2019)
G-tract RNA removes Polycomb repressive complex 2 from genes.
Nature Structural & Molecular Biology
, 26
pp. 899-909.
10.1038/s41594-019-0293-z.
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Beltran, M;
Yates, CM;
Skalska, L;
Dawson, M;
Reis, FP;
Viiri, K;
Fisher, CL;
... Jenner, RG; + view all
(2016)
The interaction of PRC2 with RNA or chromatin is mutually antagonistic.
Genome Research
, 26
(7)
pp. 896-907.
10.1101/gr.197632.115.
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Bouwman, RD;
Palser, A;
Parry, CM;
Coulter, E;
Rasaiyaah, J;
Kellam, P;
Jenner, RG;
(2014)
Human immunodeficiency virus Tat associates with a specific set of cellular RNAs.
Retrovirology
, 11
(1)
, Article 53. 10.1186/1742-4690-11-53.
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Cottone, L;
Cribbs, AP;
Khandelwal, G;
Wells, G;
Ligammari, L;
Philpott, M;
Tumber, A;
... Flanagan, AM; + view all
(2020)
Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death.
Cancer Research
, 80
(20)
pp. 4540-4551.
10.1158/0008-5472.CAN-20-1387.
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Evans, CM;
Jenner, RG;
(2013)
Transcription factor interplay in T helper cell differentiation.
Briefings in Functional Genomics
, 12
(6)
pp. 499-511.
10.1093/bfgp/elt025.
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Goldberg, R;
Clough, JN;
Roberts, LB;
Sanchez, J;
Kordasti, S;
Petrov, N;
Hertweck, A;
... Lord, GM; + view all
(2021)
A Crohn’s Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling.
Journal of Crohn's and Colitis
, 15
(12)
pp. 2054-2065.
10.1093/ecco-jcc/jjab103.
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Gunnell, A;
Webb, HM;
Wood, CD;
McClellan, MJ;
Wichaidit, B;
Kempkes, B;
Jenner, RG;
... West, MJ; + view all
(2016)
RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth.
Nucleic Acids Research
, 44
(10)
, Article 4636-4650. 10.1093/nar/gkw085.
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Hall Hickman, Alexander;
Jenner, Richard G;
(2024)
Apparent RNA bridging between PRC2 and chromatin is an artifact of non-specific chromatin precipitation upon RNA degradation.
Cell Reports
, 43
(3)
, Article 113856. 10.1016/j.celrep.2024.113856.
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Henderson, S;
Pullabhatla, V;
Hertweck, A;
de Rinaldis, E;
Herrero, J;
Lord, GM;
Jenner, RG;
(2021)
The Th1 cell regulatory circuitry is largely conserved between human and mouse.
Life Science Alliance
, 4
(11)
, Article e202101075. 10.26508/lsa.202101075.
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Hertweck, A;
Jenner, RG;
(2021)
The Study of Protein–DNA Interactions in CD4+ T-Cells Using ChIPmentation.
Methods in Molecular Biology
, 2285
pp. 201-216.
10.1007/978-1-0716-1311-5_17.
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Hertweck, Arnulf;
Vila de Mucha, Maria;
Barber, Paul R;
Dagil, Robert;
Porter, Hayley;
Ramos, Andres;
Lord, Graham M;
(2022)
The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes.
Nucleic Acids Research
, Article gkac258. 10.1093/nar/gkac258.
(In press).
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Hertweck, A;
Evans, CM;
Eskandarpour, M;
Lau, JC;
Oleinika, K;
Jackson, I;
Kelly, A;
... Jenner, RG; + view all
(2016)
T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex.
Cell Reports
, 15
(12)
pp. 2756-2770.
10.1016/j.celrep.2016.05.054.
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Lo, Jonathan W;
Schroeder, Jan-Hendrik;
Roberts, Luke B;
Mohamed, Rami;
Cozzetto, Domenico;
Beattie, Gordon;
Omer, Omer S;
... Lord, Graham M; + view all
(2024)
CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner.
Nature Communications
, 15
(1)
, Article 9520. 10.1038/s41467-024-51719-6.
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McClellan, MJ;
Wood, CD;
Ojeniyi, O;
Cooper, TJ;
Kanhere, A;
Arvey, A;
Webb, HM;
... West, MJ; + view all
(2013)
Modulation of enhancer looping and differential gene targeting by epstein-barr virus transcription factors directs cellular reprogramming.
PLoS Pathogens
, 9
(9)
, Article e1003636. 10.1371/journal.ppat.1003636.
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Omer, Omer S;
Hertweck, Arnulf;
Roberts, Luke B;
Lo, Jonathan W;
Clough, Jennie N;
Jackson, Ian;
Pantazi, Eirini D;
... Lord, Graham M; + view all
(2022)
Cyclin-dependent kinase 9 as a potential target for anti-TNF resistant inflammatory bowel disease.
Cellular and Molecular Gastroenterology and Hepatology
10.1016/j.jcmgh.2022.05.011.
(In press).
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Porter, Hayley;
Li, Yang;
Neguembor, Maria Victoria;
Beltran, Manuel;
Varsally, Wazeer;
Martin, Laura;
Cornejo, Manuel Tavares;
... Hadjur, Suzana; + view all
(2023)
Cohesin-independent STAG proteins interact with RNA and R-loops and promote complex loading.
eLife
10.7554/eLife.79386.
(In press).
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Schaller, T;
Ocwieja, KE;
Rasaiyaah, J;
Price, AJ;
Brady, TL;
Roth, SL;
Hué, S;
... Towers, GJ; + view all
(2011)
HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency.
PLoS Pathog
, 7
(12)
, Article e1002439. 10.1371/journal.ppat.1002439.
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Skalska, L;
Begley, V;
Beltran, M;
Lukauskas, S;
Khandelwal, G;
Faull, P;
Bhamra, A;
... Jenner, RG; + view all
(2021)
Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin.
Molecular Cell
, 81
(14)
2944-2959.e10.
10.1016/j.molcel.2021.05.026.
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Skalska, L;
Beltran-Nebot, M;
Ule, J;
Jenner, RG;
(2017)
Regulatory feedback from nascent RNA to chromatin and transcription.
Nature Reviews Molecular Cell Biology
, 18
(5)
pp. 331-337.
10.1038/nrm.2017.12.
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Śledzińska, A;
Vila de Mucha, M;
Bergerhoff, K;
Hotblack, A;
Demane, DF;
Ghorani, E;
Akarca, AU;
... Quezada, SA; + view all
(2020)
Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4⁺ T Cells.
Immunity
, 52
(1)
151-166.e6.
10.1016/j.immuni.2019.12.007.
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Soderquest, K;
Hertweck, A;
Giambartolomei, C;
Henderson, S;
Mohamed, R;
Goldberg, R;
Perucha, E;
... Lord, GM; + view all
(2017)
Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease.
PLOS GENETICS
, 13
(2)
10.1371/journal.pgen.1006587.
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Tavares, Manuel;
Khandelwal, Garima;
Muter, Joanne;
Viiri, Keijo;
Beltran, Manuel;
Brosens, Jan J;
Jenner, Richard G;
(2022)
JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation.
Cell Reports
, 39
(9)
, Article 110889. 10.1016/j.celrep.2022.110889.
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Teschendorff, AE;
Lee, SH;
Jones, A;
Fiegl, H;
Kalwa, M;
Wagner, W;
Chindera, K;
... Widschwendter, M; + view all
(2015)
HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer.
Genome Medicine
, 7
(1)
, Article 108. 10.1186/s13073-015-0233-4.
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Villegas-Mendez, A;
Khandelwal, G;
McGowan, LM;
Dookie, RS;
Haley, MJ;
George, C;
Sims, D;
... Couper, KN; + view all
(2020)
Exhausted CD4⁺ T Cells during Malaria Exhibit Reduced mTORc1 Activity Correlated with Loss of T-bet Expression.
The Journal of Immunology
, 205
(6)
pp. 1608-1619.
10.4049/jimmunol.2000450.
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Vlachogiannis, G;
Niederhuth, CE;
Tuna, S;
Stathopoulou, A;
Viiri, K;
de Rooij, DG;
Jenner, RG;
... Ooi, SK; + view all
(2015)
The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis.
Cell Rep
, 10
(6)
pp. 944-956.
10.1016/j.celrep.2015.01.021.
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Working / discussion paper
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Porter, Hayley;
Li, Yang;
Neguembor, Maria Victoria;
Beltran, Manuel;
Varsally, Wazeer;
Martin, Laura;
Cornejo, Manuel Tavares;
... Hadjur, Suzana; + view all
(2023)
Cohesin-independent STAG proteins interact with RNA and localise to R-loops to promote complex loading.
bioRxiv: Cold Spring Harbor, NY, USA.
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