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Number of items: 31.
Article
Canetti, D;
Nocerino, P;
Rendell, NB;
Botcher, N;
Gilbertson, JA;
Blanco, A;
Rowczenio, D;
... Taylor, GW; + view all
(2021)
Clinical ApoA-IV amyloid is associated with fibrillogenic signal sequence.
The Journal of Pathology
, 255
(3)
pp. 311-318.
10.1002/path.5770.
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Canetti, D;
Rendell, NB;
Di Vagno, L;
Gilbertson, JA;
Rowczenio, D;
Rezk, T;
Gillmore, JD;
... Taylor, GW; + view all
(2017)
Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue.
Amyloid
, 27
(4)
pp. 229-237.
10.1080/13506129.2017.1385452.
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Canetti, D;
Rendell, NB;
Gilbertson, JA;
Botcher, N;
Nocerino, P;
Blanco, A;
Di Vagno, L;
... Taylor, GW; + view all
(2020)
Diagnostic amyloid proteomics: experience of the UK National Amyloidosis Centre.
Clinical Chemistry and Laboratory Medicine
, 58
(6)
pp. 948-957.
10.1515/cclm-2019-1007.
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Cantarutti, C;
Bertoncin, P;
Corazza, A;
Giorgetti, S;
Mangione, PP;
Bellotti, V;
Fogolari, F;
(2017)
Short-Chain Alkanethiol Coating for Small-Size Gold Nanoparticles Supporting Protein Stability.
Magnetochemistry
, 3
(4)
, Article 40. 10.3390/magnetochemistry3040040.
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Cantarutti, C;
Raimondi, S;
Brancolini, G;
Corazza, A;
Giorgetti, S;
Ballico, M;
Zanini, S;
... Esposito, G; + view all
(2017)
Citrate-stabilized gold nanoparticles hinder fibrillogenesis of a pathological variant of β2-microglobulin.
Nanoscale
, 9
(11)
pp. 3941-3951.
10.1039/c6nr09362k.
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Corazza, A;
Verona, G;
Waudby, CA;
Mangione, PP;
Bingham, RP;
Uings, I;
Canetti, D;
... Bellotti, V; + view all
(2019)
Binding of monovalent and bivalent ligands by transthyretin causes different short and long distance conformational changes.
Journal of Medicinal Chemistry
, 62
(17)
pp. 8274-8283.
10.1021/acs.jmedchem.9b01037.
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Diomede, L;
Soria, C;
Romeo, M;
Giorgetti, S;
Marchese, L;
Mangione, PP;
Porcari, R;
... Stoppini, M; + view all
(2012)
C. elegans expressing human β2-microglobulin: a novel model for studying the relationship between the molecular assembly and the toxic phenotype.
PLoS One
, 7
(12)
, Article e52314. 10.1371/journal.pone.0052314.
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Faravelli, Giulia;
Mondani, Valentina;
Mangione, P Patrizia;
Raimondi, Sara;
Marchese, Loredana;
Lavatelli, Francesca;
Stoppini, Monica;
... Bellotti, Vittorio; + view all
(2022)
Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms.
Frontiers in Molecular Biosciences
, 9
, Article 830006. 10.3389/fmolb.2022.830006.
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Faravelli, G;
Raimondi, S;
Marchese, L;
Partridge, FA;
Soria, C;
Mangione, PP;
Canetti, D;
... Giorgetti, S; + view all
(2019)
C. elegans expressing D76N β_{2}-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis.
Scientific Reports
, 9
, Article 19960. 10.1038/s41598-019-56498-5.
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Halabelian, L;
Ricagno, S;
Giorgetti, S;
Santambrogio, C;
Barbiroli, A;
Pellegrino, S;
Achour, A;
... Bellotti, V; + view all
(2013)
Class I Major Histocompatibility Complex: the Trojan horse for secretion of amyloidogenic β2-microglobulin.
J Biol Chem
, 289
(6)
pp. 3318-3327.
10.1074/jbc.M113.524157.
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Mangione, PP;
Deroo, S;
Ellmerich, S;
Bellotti, V;
Kolstoe, S;
Wood, SP;
Robinson, CV;
... Taylor, GW; + view all
(2015)
Bifunctional crosslinking ligands for transthyretin.
Open Biology
, 5
(9)
, Article 150105. 10.1098/rsob.150105.
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Mangione, PP;
Esposito, G;
Relini, A;
Raimondi, S;
Porcari, R;
Giorgetti, S;
Corazza, A;
... Bellotti, V; + view all
(2013)
Structure, Folding Dynamics, and Amyloidogenesis of D76N β2-Microglobulin: ROLES OF SHEAR FLOW, HYDROPHOBIC SURFACES, AND α-CRYSTALLIN.
Journal of Biological Chemistry
, 288
(43)
30917- 30930.
10.1074/jbc.M113.498857.
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Mangione, PP;
Mazza, G;
Gilbertson, JA;
Rendell, NB;
Canetti, D;
Giorgetti, S;
Frenguelli, L;
... Bellotti, V; + view all
(2017)
Increasing the accuracy of proteomic typing by decellularisation of amyloid tissue biopsies.
Journal of Proteomics
, 165
pp. 113-118.
10.1016/j.jprot.2017.06.016.
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Mangione, PP;
Porcari, R;
Gillmore, JD;
Pucci, P;
Monti, M;
Porcari, M;
Giorgetti, S;
... Bellotti, V; + view all
(2014)
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Proceedings of the National Academy of Sciences of the United States of America
, 111
(4)
pp. 1539-1544.
10.1073/pnas.1317488111.
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Mangione, PP;
Verona, G;
Corazza, A;
Marcoux, J;
Canetti, D;
Giorgetti, S;
Raimondi, S;
... Bellotti, V; + view all
(2018)
Plasminogen activation triggers transthyretin amyloidogenesis in vitro.
Journal of Biological Chemistry
, 293
(37)
pp. 14192-14199.
10.1074/jbc.RA118.003990.
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Marcoux, J;
Mangione, PP;
Porcari, R;
Degiacomi, MT;
Verona, G;
Taylor, GW;
Giorgetti, S;
... Bellotti, V; + view all
(2015)
A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis.
EMBO Mol Med
, 7
(10)
pp. 1337-1349.
10.15252/emmm.201505357.
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Mazza, G;
Simons, JP;
Al-Shawi, R;
Ellmerich, S;
Urbani, L;
Giorgetti, S;
Taylor, GW;
... Mangione, PP; + view all
(2015)
Amyloid persistence in decellularized liver: biochemical and histopathological characterization.
Amyloid
, 23
(1)
pp. 1-7.
10.3109/13506129.2015.1110518.
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Moura, A;
Nocerino, P;
Gilbertson, JA;
Rendell, NB;
Mangione, PP;
Verona, G;
Rowczenio, D;
... Canetti, D; + view all
(2020)
Lysozyme amyloid: evidence for the W64R variant by proteomics in the absence of the wild type protein.
[Letter].
Amyloid
10.1080/13506129.2020.1720637.
(In press).
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Natalello, A;
Mangione, PP;
Giorgetti, S;
Porcari, R;
Marchese, L;
Zorzoli, I;
Relini, A;
... Raimondi, S; + view all
(2016)
Co-fibrillogenesis of Wild-type and D76N β₂-Microglobulin: THE CRUCIAL ROLE OF FIBRILLAR SEEDS.
Journal of Biological Chemistry
, 291
(18)
pp. 9678-9689.
10.1074/jbc.M116.720573.
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Ozawa, D;
Nomura, R;
Mangione, PP;
Hasegawa, K;
Okoshi, T;
Porcari, R;
Bellotti, V;
(2016)
Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro.
Scientific Reports
, 6
, Article 29077. 10.1038/srep29077.
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Pepys, MB;
Gallimore, JR;
Lloyd, J;
Li, Z;
Graham, D;
Taylor, GW;
Ellmerich, S;
... Hawkins, PN; + view all
(2012)
Isolation and characterization of pharmaceutical grade human pentraxins, serum amyloid P component and C-reactive protein, for clinical use.
Journal of Immunological Methods
, 384
(1-2)
92 - 102.
10.1016/j.jim.2012.07.013.
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Porcari, R;
Proukakis, C;
Waudby, CA;
Bolognesi, B;
Mangione, PP;
Paton, JF;
Mullin, S;
... Bellotti, V; + view all
(2015)
The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein.
J Biol Chem
, 290
(4)
2395 - 2404.
10.1074/jbc.M114.610527.
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Raimondi, S;
Barbarini, N;
Mangione, P;
Esposito, G;
Ricagno, S;
Bolognesi, M;
Zorzoli, I;
... Bellotti, V; + view all
(2011)
The two tryptophans of β2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure.
BMC Evolutionary Biology
, 11
(June 2)
, Article 159. 10.1186/1471-2148-11-159.
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Raimondi, S;
Mangione, PP;
Verona, G;
Canetti, D;
Nocerino, P;
Marchese, L;
Piccarducci, R;
... Bellotti, V; + view all
(2020)
Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils.
Journal of Biological Chemistry
, 295
(33)
pp. 11379-11387.
10.1074/jbc.RA120.014026.
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Raimondi, S;
Porcari, R;
Mangione, PP;
Verona, G;
Marcoux, J;
Giorgetti, S;
Taylor, GW;
... Bellotti, V; + view all
(2017)
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo.
Scientific Reports
, 7
, Article 46711. 10.1038/srep46711.
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Rezk, T;
Gilbertson, JA;
Mangione, PP;
Rowczenio, D;
Rendell, N;
Canetti, D;
Lachmann, HJ;
... Gillmore, JD; + view all
(2019)
The complementary role of histology and proteomics for diagnosis and typing of systemic amyloidosis.
Journal of Pathology: Clinical Research
, 5
(3)
pp. 145-153.
10.1002/cjp2.126.
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Simons, JP;
Al-Shawi, R;
Ellmerich, S;
Speck, I;
Aslam, S;
Hutchinson, WL;
Mangione, PP;
... Hawkins, PN; + view all
(2013)
Pathogenetic mechanisms of amyloid A amyloidosis.
Proceedings of the National Academy of Sciences
, 110
(40)
pp. 16115-16120.
10.1073/pnas.1306621110.
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Slamova, I;
Adib, R;
Ellmerich, S;
Golos, MR;
Gilbertson, JA;
Botcher, N;
Canetti, D;
... Simons, JP; + view all
(2021)
Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis.
Nature Communications
, 12
(1)
, Article 7112. 10.1038/s41467-021-27416-z.
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Taylor, GW;
Gilbertson, JA;
Sayed, R;
Blanco, A;
Rendell, NB;
Rowczenio, D;
Rezk, T;
... Gillmore, JD; + view all
(2019)
Proteomic Analysis for the Diagnosis of Fibrinogen Aα-Chain Amyloidosis.
Kidney International Reports
10.1016/j.ekir.2019.04.007.
(In press).
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Valleix, S;
Verona, G;
Jourde-Chiche, N;
Nédelec, B;
Mangione, PP;
Bridoux, F;
Mangé, A;
... Bellotti, V; + view all
(2016)
D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile.
Nature Communications
, 7
, Article 10353. 10.1038/ncomms10353.
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Verona, G;
Mangione, P;
Raimondi, S;
Giorgetti, S;
Faravelli, G;
Porcari, R;
Corazza, A;
... Bellotti, VL; + view all
(2017)
Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel.
Scientific Reports
, 7
, Article 182. 10.1038/s41598-017-00338-x.
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