Browse by UCL people
Group by: Type | Date
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Number of items: 30.
Article
Al-Qassab, Hind;
Smith, Mark A;
Irvine, Elaine E;
Guillermet-Guibert, Julie;
Claret, Marc;
Choudhury, Agharul I;
Selman, Colin;
... Withers, Dominic J; + view all
(2009)
Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons.
Cell Metabolism
, 10
(5)
pp. 343-354.
10.1016/j.cmet.2009.09.008.
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Barbera, JPM;
Clements, M;
Thomas, P;
Rodriguez, T;
Meloy, D;
Kioussis, D;
Beddington, RSP;
(2000)
The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation.
Development
, 127
(11)
pp. 2433-2445.
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Brickman, JM;
Clements, M;
Tyrell, R;
McNay, D;
Woods, K;
Warner, J;
Stewart, A;
... Dattani, M; + view all
(2001)
Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders.
DEVELOPMENT
, 128
(24)
5189 - 5199.
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Brooks, Lucy J;
Clements, Melanie P;
Burden, Jemima J;
Kocher, Daniela;
Richards, Luca;
Devesa, Sara Castro;
Zakka, Leila;
... Parrinello, Simona; + view all
(2022)
Author Correction: The white matter is a pro-differentiative niche for glioblastoma.
Nature Communications
, 13
(1)
, Article 2163. 10.1038/s41467-022-29916-y.
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Brooks, LJ;
Clements, MP;
Burden, JJ;
Kocher, D;
Richards, L;
Devesa, SC;
Zakka, L;
... Parrinello, S; + view all
(2021)
The white matter is a pro-differentiative niche for glioblastoma.
Nature Communications
, 12
, Article 2184. 10.1038/s41467-021-22225-w.
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Cantley, J;
Selman, C;
Shukla, D;
Abramov, AY;
Forstreuter, F;
Esteban, MA;
Claret, M;
... Withers, DJ; + view all
(2009)
Deletion of the von Hippel–Lindau gene in pancreatic β cells impairs glucose homeostasis in mice.
Journal of Clinical Investigation
, 119
(1)
pp. 125-135.
10.1172/JCI26934.
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Choudhury, AI;
Heffron, H;
Smith, MA;
Al-Qassab, H;
Xu, AW;
Selman, C;
Simmgen, M;
... Withers, DJ; + view all
(2005)
The role of insulin receptor substrate 2 in hypothalamic and beta cell function.
J CLIN INVEST
, 115
(4)
940 - 950.
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Claret, M;
Smith, MA;
Batterham, RL;
Selman, C;
Choudhury, AI;
Fryer, LGD;
Clements, M;
... Withers, DJ; + view all
(2007)
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons.
J CLIN INVEST
, 117
(8)
2325 - 2336.
10.1172/JCI31516.
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Clements, Melanie;
Simpson Ragdale, Holly;
Garcia-Diaz, Claudia;
Parrinello, Simona;
(2024)
Generation of immunocompetent somatic glioblastoma mouse models through in situ transformation of subventricular zone neural stem cells.
STAR Protocols
, 5
(1)
, Article 102928. 10.1016/j.xpro.2024.102928.
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Clements, Melanie;
Tang, Wenhao;
Florjanic Baronik, Zan;
Simpson Ragdale, Holly;
Oria, Roger;
Volteras, Dimitrios;
White, Ian J;
... Parrinello, Simona; + view all
(2025)
Axonal injury is a targetable driver of glioblastoma progression.
Nature
, 646
pp. 452-461.
10.1038/s41586-025-09411-2.
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Clements, M;
Brickman, JM;
Jones, CM;
Clements, M;
Smith, JC;
Beddington, RS;
(2000)
Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function.
Development
, 127
(11)
pp. 2303-2315.
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Clements, M;
Pernaute, B;
Vella, F;
Rodriguez, TA;
(2011)
Crosstalk between Nodal/Activin and MAPK p38 Signaling Is Essential for Anterior-Posterior Axis Specification.
Current Biology
, 21
(15)
pp. 1289-1295.
10.1016/j.cub.2011.06.048.
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Clements, MP;
Byrne, E;
Camarillo Guerrero, LF;
Cattin, A-L;
Zakka, L;
Ashraf, A;
Burden, JJ;
... Parrinello, S; + view all
(2017)
The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration.
Neuron
, 96
(1)
98-114.e7.
10.1016/j.neuron.2017.09.008.
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Dunwoodie, S;
Clements, M;
Sparrow, DB;
Sa, X;
Conlon, RA;
Beddington, RS;
(2002)
Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm.
Development
, 129
(7)
pp. 1795-1806.
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Galvez-Cancino, Felipe;
Navarrete, Mariela;
Beattie, Gordon;
Puccio, Simone;
Conde-Gallastegi, Enrique;
Foster, Kane;
Morris, Yasmin;
... Quezada, Sergio A; + view all
(2025)
Correction:
Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies.
[Corrigendum].
Immunity
, 58
(7)
pp. 1862-1864.
10.1016/j.immuni.2025.05.019.
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Garcia-Diaz, Claudia;
Pöysti, Anni;
Mereu, Elisabetta;
Clements, Melanie P;
Brooks, Lucy J;
Galvez-Cancino, Felipe;
Castillo, Simon P;
... Parrinello, Simona; + view all
(2023)
Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin.
Cell Reports
, 42
(5)
, Article 112472. 10.1016/j.celrep.2023.112472.
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Guo, L;
Davis, B;
Nizari, S;
Normando, EM;
Shi, H;
Galvao, J;
Turner, L;
... Cordeiro, MF; + view all
(2014)
Direct optic nerve sheath (DONS) application of Schwann cells prolongs retinal ganglion cell survival in vivo.
Cell Death Dis
, 5
, Article e1460. 10.1038/cddis.2014.399.
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Karamched, Saketh R;
Gorup, Dunja;
Tolomeo, Daniele;
Brooks, Lucy J;
Gong, Ting;
Jørgensen, Andreas Christ Sølvsten;
Hill, Ciaran Scott;
... Lythgoe, Mark F; + view all
(2025)
Detecting glioblastoma infiltration beyond conventional imaging tumour margins using MTE-NODDI.
Imaging Neuroscience
, 3
pp. 1-14.
10.1162/imag_a_00472.
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Krusche, B;
Ottone, C;
clements, MP;
Johnstone, ER;
Goetsch, K;
Lieven, H;
Mota, SG;
... Parrinello, S; + view all
(2016)
EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells.
eLife
, 5
, Article e14845. 10.7554/eLife.14845.
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Marqués-Torrejón, MÁ;
Williams, CAC;
Southgate, B;
Alfazema, N;
Clements, MP;
Garcia-Diaz, C;
Blin, C;
... Pollard, SM; + view all
(2021)
LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells.
Nature Communications
, 12
(1)
, Article 2594. 10.1038/s41467-021-22813-w.
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Ottone, Cristina;
Krusche, Benjamin;
Whitby, Ariadne;
Clements, Melanie;
Quadrato, Giorgia;
Pitulescu, Mara E;
Adams, Ralf H;
(2014)
Direct cell–cell contact with the vascular niche maintains quiescent neural stem cells.
Nature Cell Biology
, 16
(11)
pp. 1045-1056.
10.1038/ncb3045.
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Rodriguez, TA;
Srinivas, S;
Clements, MP;
Smith, JC;
Beddington, RSP;
(2005)
Induction and migration of the anterior visceral endoderm is regulated by the extra-embryonic ectoderm.
Development
, 132
(11)
pp. 2513-2520.
10.1242/dev.01847.
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Sousa-Nunes, R;
Rana, AA;
Kettleborough, R;
Brickman, JM;
Clements, M;
Forrest, A;
Grimmond, S;
... Beddington, RS; + view all
(2003)
Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection.
Genome Research
, 13
(12)
pp. 2609-2620.
10.1101/gr.1362303.
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Srinivas, S;
Rodriguez, T;
Clements, M;
Smith, JC;
Beddington, RSP;
(2004)
Active cell migration drives the unilateral movements of the anterior visceral endoderm.
Development
, 131
(5)
pp. 1157-1164.
10.1242/dev.01005.
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Stuckey, Daniel W;
Clements, Melanie;
Di-Gregorio, Aida;
Senner, Claire E;
Le Tissier, Paul;
Srinivas, Shankar;
Rodriguez, Tristan A;
(2011)
Coordination of cell proliferation and anterior-posterior axis establishment in the mouse embryo.
Development
, 138
(8)
pp. 1521-1530.
10.1242/dev.063537.
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Stuckey, DW;
Di Gregorio, A;
Clements, M;
Rodriguez, TA;
(2011)
Correct Patterning of the Primitive Streak Requires the Anterior Visceral Endoderm.
PLoS ONE
, 6
(3)
, Article e17620. 10.1371/journal.pone.0017620.
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Trichas, G;
Joyce, B;
Crompton, LA;
Wilkins, V;
Clements, M;
Tada, M;
Rodriguez, TA;
(2011)
Nodal Dependent Differential Localisation of Dishevelled-2 Demarcates Regions of Differing Cell Behaviour in the Visceral Endoderm.
PLoS Biology
, 9
(2)
, Article e1001019. 10.1371/journal.pbio.1001019.
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Woods, Angela;
Heslegrave, Amanda J;
Muckett, Phillip J;
Levene, Adam P;
Clements, Melanie;
Mobberley, Margaret;
Ryder, Timothy A;
... Carling, David; + view all
(2011)
LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice.
Biochemical Journal
, 434
(1)
pp. 49-60.
10.1042/BJ20101721.
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Working / discussion paper
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Amodeo, Valeria;
Davies, Timothy;
Martinez-Segura, Amalia;
Clements, Melanie;
Ragdale, Holly Simpson;
Bailey, Andrew;
Silva Dos Santos, Mariana;
... Parrinello, Simona; + view all
(2022)
Diet suppresses tumour initiation by maintaining quiescence of mutation-bearing neural stem cells.
bioRxiv: Cold Spring Harbor, NY, USA.
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Garcia-Diaz, Claudia;
Mereu, Elisabetta;
Clements, Melanie;
Pöysti, Anni;
Galvez-Cancino, Felipe;
Castillo, Simon;
Courtot, Lilas;
... Parrinello, Simona; + view all
(2021)
Glioblastoma cell fate is differentially regulated by the microenvironments of the tumour bulk and infiltrative margin.
bioRxiv: Cold Spring Harbor, NY, USA.
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