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Number of items: 54.
Article
Bello, OD;
Jouannot, O;
Chaudhuri, A;
Stroeva, E;
Coleman, J;
Volynski, KE;
Rothman, JE;
(2018)
Synaptotagmin oligomerization is essential for calcium control of regulated exocytosis.
Proceedings of the National Academy of Sciences of the United States of America
, 115
(32)
E7624-E7631.
10.1073/pnas.1808792115.
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Bottanelli, F;
Kilian, N;
Ernst, AM;
Rivera-Molina, F;
Schroeder, LK;
Kromann, EB;
Lessard, MD;
... Rothman, JE; + view all
(2017)
A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi.
Molecular Biology of the Cell
, 28
(12)
pp. 1676-1687.
10.1091/mbc.E16-12-0863.
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Chelban, V;
Patel, N;
Vandrovcova, J;
Zanetti, MN;
Lynch, DS;
Ryten, M;
Botia, JA;
... Houlden, H; + view all
(2017)
Mutations in NKX6-2 Cause Progressive Spastic Ataxia and Hypomyelination.
American Journal of Human Genetics
, 100
(6)
pp. 969-977.
10.1016/j.ajhg.2017.05.009.
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Chelban, V;
Wilson, MP;
Warman Chardon, J;
Vandrovcova, J;
Zanetti, MN;
Zamba-Papanicolaou, E;
Efthymiou, S;
... SYNaPS Study Group, .; + view all
(2019)
PDXK mutations cause polyneuropathy responsive to PLP supplementation.
Annals of Neurology
10.1002/ana.25524.
(In press).
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Coleman, J;
Jouannot, O;
Ramakrishnan, SK;
Zanetti, MN;
Wang, J;
Salpietro, V;
Houlden, H;
... Krishnakumar, SS; + view all
(2018)
PRRT2 Regulates Synaptic Fusion by Directly Modulating SNARE Complex Assembly.
Cell Reports
, 22
(3)
pp. 820-831.
10.1016/j.celrep.2017.12.056.
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Dancourt, J;
Zheng, H;
Bottanelli, F;
Allgeyer, ES;
Bewersdorf, J;
Graham, M;
Liu, X;
... Lavieu, G; + view all
(2016)
Small cargoes pass through synthetically glued Golgi stacks.
FEBS Letters
, 590
(12)
pp. 1675-1686.
10.1002/1873-3468.12210.
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Dunlop, MH;
Ernst, AM;
Schroeder, LK;
Toomre, DK;
Lavieu, G;
Rothman, JE;
(2017)
Land-locked mammalian Golgi reveals cargo transport between stable cisternae.
Nature Communications
, 8
, Article 432. 10.1038/s41467-017-00570-z.
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Efthymiou, S;
Salpietro, V;
Malintan, N;
Poncelet, M;
Kriouile, Y;
Fortuna, S;
De Zorzi, R;
... Houlden, H; + view all
(2019)
Biallelic mutations in neurofascin cause neurodevelopmental impairment and peripheral demyelination.
Brain
, 142
(10)
pp. 2948-2964.
10.1093/brain/awz248.
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Erdmann, RS;
Baguley, SW;
Richens, JH;
Wissner, RF;
Xi, Z;
Allgeyer, ES;
Zhong, S;
... Toomre, D; + view all
(2019)
Labeling Strategies Matter for Super-Resolution Microscopy: A Comparison between HaloTags and SNAP-tags.
Cell Chemical Biology
, 26
(4)
584-592.e6.
10.1016/j.chembiol.2019.01.003.
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Ernst, AM;
Syed, SA;
Zaki, O;
Bottanelli, F;
Zheng, H;
Hacke, M;
Xi, Z;
... Rothman, JE; + view all
(2018)
S-Palmitoylation Sorts Membrane Cargo for Anterograde Transport in the Golgi.
Developmental Cell
, 47
(4)
479-493.e7.
10.1016/j.devcel.2018.10.024.
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Francois-Martin, C;
Rothman, JE;
Pincet, F;
(2017)
Low energy cost for optimal speed and control of membrane fusion.
Proceedings of the National Academy of Sciences of the United States of America
, 114
(6)
pp. 1238-1241.
10.1073/pnas.1621309114.
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Gruget, C;
Bello, O;
Coleman, J;
Krishnakumar, SS;
Perez, E;
Rothman, JE;
Pincet, F;
(2020)
Synaptotagmin-1 membrane binding is driven by the C2B domain and assisted cooperatively by the C2A domain.
Scientific Reports
, 10
(1)
p. 18011.
10.1038/s41598-020-74923-y.
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Gruget, C;
Coleman, J;
Bello, O;
Krishnakumar, SS;
Perez, E;
Rothman, JE;
Pincet, F;
(2018)
Rearrangements under confinement lead to increased binding energy of Synaptotagmin-1 with anionic membranes in Mg2+ and Ca2+.
FEBS Letters
, 592
(9)
pp. 1497-1506.
10.1002/1873-3468.13040.
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Grushin, K;
Wang, J;
Coleman, J;
Rothman, JE;
Sindelar, CV;
Krishnakumar, SS;
(2019)
Structural basis for the clamping and Ca²⁺ activation of SNARE-mediated fusion by synaptotagmin.
Nature Communications
, 10
, Article 2413. 10.1038/s41467-019-10391-x.
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Hao, Xiang;
Allgeyer, Edward S;
Lee, Dong-Ryoung;
Antonello, Jacopo;
Watters, Katherine;
Gerdes, Julianne A;
Schroeder, Lena K;
... Bewersdorf, Joerg; + view all
(2021)
Three-dimensional adaptive optical nanoscopy for thick specimen imaging at sub-50-nm resolution.
Nature Methods
, 18
pp. 688-693.
10.1038/s41592-021-01149-9.
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Heo, P;
Ramakrishnan, S;
Coleman, J;
Rothman, JE;
Fleury, J-B;
Pincet, F;
(2019)
Highly Reproducible Physiological Asymmetric Membrane with Freely Diffusing Embedded Proteins in a 3D-Printed Microfluidic Setup.
Small
, 15
(21)
, Article 1900725. 10.1002/smll.201900725.
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Huang, F;
Sirinakis, G;
Allgeyer, ES;
Schroeder, LK;
Duim, WC;
Kromann, EB;
Phan, T;
... Bewersdorf, J; + view all
(2016)
Ultra-High Resolution 3D Imaging of Whole Cells.
Cell
, 166
(4)
pp. 1028-1040.
10.1016/j.cell.2016.06.016.
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Karatekin, E;
Rothman, JE;
(2018)
FEBS Letters Special Issue on Exocytosis and Endocytosis.
[Editorial comment].
FEBS Letters
, 592
(21)
pp. 3477-3479.
10.1002/1873-3468.13274.
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Kilian, N;
Goryaynov, A;
Lessard, MD;
Hooker, G;
Toomre, D;
Rothman, JE;
Bewersdorf, J;
(2018)
Assessing photodamage in live-cell STED microscopy.
[Letter].
Nature Methods
, 15
(10)
pp. 755-756.
10.1038/s41592-018-0145-5.
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Li, Feng;
Sundaram, Ramalingam Venkat Kalyana;
Gatta, Alberto T;
Coleman, Jeff;
Ramakrishnan, Sathish;
Krishnakumar, Shyam S;
Pincet, Frederic;
(2021)
Vesicle capture by membrane-bound Munc13-1 requires self-assembly into discrete clusters.
FEBS Letters
, 595
(17)
pp. 2185-2196.
10.1002/1873-3468.14157.
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Li, F;
Tiwari, N;
Rothman, JE;
Pincet, F;
(2016)
Kinetic barriers to SNAREpin assembly in the regulation of membrane docking/priming and fusion.
Proceedings of the National Academy of Sciences of the United States of America
, 113
(38)
pp. 10536-10541.
10.1073/pnas.1604000113.
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Li, X;
Radhakrishnan, A;
Grushin, K;
Kasula, R;
Chaudhuri, A;
Gomathinayagam, S;
Krishnakumar, SS;
... Rothman, JE; + view all
(2019)
Symmetrical organization of proteins under docked synaptic vesicles.
FEBS Letters
, 593
(2)
pp. 144-153.
10.1002/1873-3468.13316.
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Manca, F;
Pincet, F;
Truskinovsky, L;
Rothman, JE;
Foret, L;
Caruel, M;
(2019)
SNARE machinery is optimized for ultrafast fusion.
Proceedings of the National Academy of Sciences
, 116
(7)
pp. 2435-2442.
10.1073/pnas.1820394116.
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Michalski, N;
Goutman, JD;
Auclair, SM;
de Monvel, JB;
Tertrais, M;
Emptoz, A;
Parrin, A;
... Petit, C; + view all
(2017)
Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses.
eLIFE
, 6
, Article e31013. 10.7554/eLife.31013.
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Mostafavi, H;
Thiyagarajan, S;
Stratton, BS;
Karatekin, E;
Warner, JM;
Rothman, JE;
O'Shaughnessy, B;
(2017)
Entropic forces drive self-organization and membrane fusion by SNARE proteins.
Proceedings of the National Academy of Sciences of the United States of America
, 114
(21)
pp. 5455-5460.
10.1073/pnas.1611506114.
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Paumet, F;
Wesolowski, J;
Garcia-Diaz, A;
Rothman, JE;
Delevoye, C;
Aulner, N;
Shuman, HA;
(2009)
Intracellular bacteria encode inhibitory SNARE-like proteins.
PLoS ONE
, 4
(10)
, Article e7375. 10.1371/journal.pone.0007375.
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Pincet, F;
Adrien, V;
Yang, R;
Delacotte, J;
Rothman, JE;
Urbach, W;
Tareste, D;
(2016)
FRAP to Characterize Molecular Diffusion and Interaction in Various Membrane Environments.
PLoS ONE
, 11
(7)
, Article e0158457. 10.1371/journal.pone.0158457.
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Praschberger, R;
Lowe, SA;
Malintan, NT;
Giachello, CNG;
Patel, N;
Houlden, H;
Kullmann, DM;
... Jepson, JEC; + view all
(2017)
Mutations in Membrin/GOSR2 Reveal Stringent Secretory Pathway Demands of Dendritic Growth and Synaptic Integrity.
Cell Rep
, 21
(1)
pp. 97-109.
10.1016/j.celrep.2017.09.004.
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Radhakrishnan, A;
Li, X;
Grushin, K;
Krishnakumar, SS;
Liu, J;
Rothman, JE;
(2021)
Symmetrical arrangement of proteins under release-ready vesicles in presynaptic terminals.
Proceedings of the National Academy of Sciences of the United States of America
, 118
(5)
, Article e2024029118. 10.1073/pnas.2024029118.
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Ramakrishnan, S;
Bera, M;
Coleman, J;
Krishnakumar, SS;
Pincet, F;
Rothman, JE;
(2019)
Synaptotagmin oligomers are necessary and can be sufficient to form a Ca2+-sensitive fusion clamp.
FEBS Letters
, 593
(2)
pp. 154-162.
10.1002/1873-3468.13317.
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Ramakrishnan, S;
Gohlke, A;
Li, F;
Coleman, J;
Xu, W;
Rothman, JE;
Pincet, F;
(2018)
High-Throughput Monitoring of Single Vesicle Fusion Using Freestanding Membranes and Automated Analysis.
Langmuir
, 34
(20)
pp. 5849-5859.
10.1021/acs.langmuir.8b00116.
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Rebane, AA;
Wang, B;
Ma, L;
Qu, H;
Coleman, J;
Krishnakumar, S;
Rothman, JE;
(2018)
Two Disease-Causing SNAP-25B Mutations Selectively Impair SNARE C-terminal Assembly.
Journal of Molecular Biology
, 430
(4)
pp. 479-490.
10.1016/j.jmb.2017.10.012.
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Rebane, AA;
Ziltener, P;
LaMonica, LC;
Bauer, AH;
Zheng, H;
López-Montero, I;
Pincet, F;
... Ernst, AM; + view all
(2019)
Liquid-liquid phase separation of the Golgi matrix protein GM130.
FEBS Letters
10.1002/1873-3468.13715.
(In press).
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Rothman, JE;
(2022)
The gripping story of integrins.
Cell
, 185
(21)
pp. 3844-3848.
10.1016/j.cell.2022.09.017.
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Rothman, JE;
(2019)
Jim's View: Is the Golgi stack a phase-separated liquid crystal?
[Editorial comment].
FEBS Letters
, 593
(19)
pp. 2701-2705.
10.1002/1873-3468.13609.
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Rothman, JE;
(2019)
Jim's view: Patience vs urgency.
[Editorial comment].
FEBS Letters
, 593
(16)
pp. 2081-2082.
10.1002/1873-3468.13518.
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Rothman, JE;
(2019)
Jim's view: What makes transformative basic science possible?
[Editorial comment].
FEBS Letters
, 593
(15)
pp. 1877-1878.
10.1002/1873-3468.13517.
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Rothman, JE;
(2019)
Jim's view: Why basic science?
[Editorial comment].
FEBS Letters
, 593
(14)
pp. 1693-1697.
10.1002/1873-3468.13510.
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Rothman, JE;
(2018)
Jim's view: analog to digital conversion in biology.
[Editorial comment].
FEBS Letters
, 592
(24)
pp. 4009-4010.
10.1002/1873-3468.13308.
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Rothman, JE;
(2018)
Jim's View: "Playing Billiards with Science".
FEBS Letters
, 592
(14)
pp. 2381-2382.
10.1002/1873-3468.13125.
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Rothman, JE;
Krishnakumar, SS;
Grushin, K;
Pincet, F;
(2017)
Hypothesis - buttressed rings assemble, clamp, and release SNAREpins for synaptic transmission.
FEBS Letters
, 591
(21)
pp. 3459-3480.
10.1002/1873-3468.12874.
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Salpietro, V;
Dixon, CL;
Guo, H;
Bello, OD;
Vandrovcova, J;
Efthymiou, S;
Maroofian, R;
... Houlden, H; + view all
(2019)
AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders.
Nature Communications
, 10
(1)
, Article 3094. 10.1038/s41467-019-10910-w.
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Salpietro, V;
Lin, W;
Delle Vedove, A;
Storbeck, M;
Liu, Y;
Efthymiou, S;
Manole, A;
... Houlden, H; + view all
(2017)
Homozygous Mutations in VAMP1 Cause a Presynaptic Congenital Myasthenic Syndrome.
Annals of Neurology
, 81
(4)
pp. 597-603.
10.1002/ana.24905.
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Salpietro, V;
Malintan, NT;
Llano-Rivas, I;
Spaeth, CG;
Efthymiou, S;
Striano, P;
Vandrovcova, J;
... Houlden, H; + view all
(2019)
Mutations in the Neuronal Vesicular SNARE VAMP2 Affect Synaptic Membrane Fusion and Impair Human Neurodevelopment.
American Journal of Human Genetics
, 104
(4)
pp. 721-730.
10.1016/j.ajhg.2019.02.016.
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Schueder, Florian;
Rivera-Molina, Felix;
Su, Maohan;
Marin, Zach;
Kidd, Phylicia;
Rothman, James E;
Toomre, Derek;
(2024)
Unraveling cellular complexity with transient adapters in highly multiplexed super-resolution imaging.
Cell
, 187
(7)
1769-1784.e18.
10.1016/j.cell.2024.02.033.
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Shu, T;
Jin, H;
Rothman, JE;
Zhang, Y;
(2020)
Munc13-1 MUN domain and Munc18-1 cooperatively chaperone SNARE assembly through a tetrameric complex.
Proceedings of The National Academy of Sciences of The United States of America (PNAS)
, 117
(2)
pp. 1036-1041.
10.1073/pnas.1914361117.
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Sundaram, RVK;
Jin, H;
Li, F;
Shu, T;
Coleman, J;
Yang, J;
Pincet, F;
... Krishnakumar, SS; + view all
(2020)
Munc13 binds and recruits SNAP25 to chaperone SNARE complex assembly.
FEBS Letters
, 595
(3)
pp. 297-309.
10.1002/1873-3468.14006.
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Tagliatti, E;
Bello, OD;
Mendonça, PRF;
Kotzadimitriou, D;
Nicholson, E;
Coleman, J;
Timofeeva, Y;
... Volynski, KE; + view all
(2020)
Synaptotagmin 1 oligomers clamp and regulate different modes of neurotransmitter release.
Proceedings of the National Academy of Sciences of the United States of America
, 117
(7)
pp. 3819-3827.
10.1073/pnas.1920403117.
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Takakura, H;
Zhang, Y;
Erdmann, RS;
Thompson, AD;
Lin, Y;
McNellis, B;
Rivera-Molina, F;
... Toomre, D; + view all
(2017)
Long time-lapse nanoscopy with spontaneously blinking membrane probes.
Nature Biotechnology
, 35
(8)
pp. 773-780.
10.1038/nbt.3876.
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Tiwari, N;
Graham, M;
Liu, X;
Yue, X;
Zhu, L;
Meshram, D;
Choi, S;
... Lee, I; + view all
(2019)
Golgin45-Syntaxin5 Interaction Contributes to Structural Integrity of the Golgi Stack.
Scientific Reports
, 9
, Article 12465. 10.1038/s41598-019-48875-x.
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Wang, J;
Li, F;
Bello, OD;
Sindelar, CV;
Pincet, F;
Krishnakumar, SS;
Rothman, JE;
(2017)
Circular oligomerization is an intrinsic property of synaptotagmin.
eLife
, 6
, Article e27441. 10.7554/eLife.27441.
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Yue, X;
Bao, M;
Christiano, R;
Li, S;
Mei, J;
Zhu, L;
Mao, F;
... Lee, I; + view all
(2017)
ACBD3 functions as a scaffold to organize the Golgi stacking proteins and a Rab33b-GAP.
FEBS Letters
, 591
(18)
pp. 2793-2802.
10.1002/1873-3468.12780.
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Zanetti, MN;
Bello, OD;
Wang, J;
Coleman, J;
Cai, Y;
Sindelar, CV;
Rothman, JE;
(2016)
Ring-like Oligomers of Synaptotagmins and Related C2 Domain Proteins.
eLIFE
, 5
, Article e17262.. 10.7554/eLife.17262.
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Zhang, X;
Rebane, AA;
Ma, L;
Li, F;
Jiao, J;
Qu, H;
Pincet, F;
... Zhang, Y; + view all
(2016)
Stability, folding dynamics, and long-range conformational transition of the synaptic t-SNARE complex.
Proceedings of the National Academy of Sciences of the United States of America
, 113
(50)
E8031-E8040.
10.1073/pnas.1605748113.
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