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Number of items: 75.
A
Abbafati, C;
Abbas, KM;
Abbasi, M;
Abbasifard, M;
Abbasi-Kangevari, M;
Abbastabar, H;
Abd-Allah, F;
... Murray, CJL; + view all
(2020)
Five insights from the Global Burden of Disease Study 2019.
The Lancet
, 396
(10258)
pp. 1135-1159.
10.1016/S0140-6736(20)31404-5.
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Alexander, N;
Alexander, DC;
Barkhof, F;
Denaxas, S;
(2020)
Using Unsupervised Learning to Identify Clinical Subtypes of Alzheimer's Disease in Electronic Health Records.
Studies in Health Technology and Informatics
, 270
pp. 499-503.
10.3233/SHTI200210.
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B
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Banerjee, A;
Katsoulis, M;
Lai, AG;
Pasea, L;
Treibel, TA;
Manisty, C;
Denaxas, S;
... Moon, JC; + view all
(2020)
Clinical academic research in the time of Corona: A simulation study in England and a call for action.
PLoS One
, 15
(8)
, Article e0237298. 10.1371/journal.pone.0237298.
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Banerjee, A;
Pasea, L;
Harris, S;
Gonzalez-Izquierdo, A;
Torralbo, A;
Shallcross, L;
Noursadeghi, M;
... Hemingway, H; + view all
(2020)
Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study.
The Lancet
10.1016/S0140-6736(20)30854-0.
(In press).
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Barrett, JE;
Cakiroglu, A;
Bunce, C;
Shah, A;
Denaxas, S;
(2020)
Selective recruitment designs for improving observational studies using electronic health records.
Statistics in Medicine
10.1002/sim.8556.
(In press).
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Bean, DM;
Al-Chalabi, A;
Dobson, RJB;
Iacoangeli, A;
(2020)
A Knowledge-Based Machine Learning Approach to Gene Prioritisation in Amyotrophic Lateral Sclerosis.
Genes
, 11
(6)
, Article 668. 10.3390/genes11060668.
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Bean, DM;
Kraljevic, Z;
Searle, T;
Bendayan, R;
Kevin O, G;
Pickles, A;
Folarin, A;
... Dobson, RJ; + view all
(2020)
ACE-inhibitors and Angiotensin-2 Receptor Blockers are not associated with severe SARS-COVID19 infection in a multi-site UK acute Hospital Trust.
European Journal of Heart Failure
, 22
(6)
pp. 967-974.
10.1002/ejhf.1924.
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Bendayan, R;
Mascio, A;
Stewart, R;
Roberts, A;
Dobson, RJ;
(2020)
Cognitive Trajectories in Comorbid Dementia With Schizophrenia or Bipolar Disorder: The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Case Register.
The American Journal of Geriatric Psychiatry
10.1016/j.jagp.2020.10.018.
(In press).
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Borges, MC;
Schmidt, AF;
Jefferis, B;
Wannamethee, SG;
Lawlor, DA;
Kivimaki, M;
Kumari, M;
... UCLEB Consortium**; + view all
(2020)
Circulating Fatty Acids and Risk of Coronary Heart Disease and Stroke: Individual Participant Data Meta-Analysis in Up to 16 126 Participants.
J Am Heart Assoc
, 9
(5)
, Article e013131. 10.1161/JAHA.119.013131.
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C
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Chung, S-C;
Providencia, R;
Sofat, R;
(2020)
Association between Angiotensin Blockade and Incidence of Influenza in the United Kingdom.
The New England Journal of Medicine
, 383
pp. 397-400.
10.1056/NEJMc2005396.
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D
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de Lucia, C;
Murphy, T;
Steves, CJ;
Dobson, RJB;
Proitsi, P;
Thuret, S;
(2020)
Lifestyle mediates the role of nutrient-sensing pathways in cognitive aging: cellular and epidemiological evidence.
Communications Biology
, 3
(1)
, Article 157. 10.1038/s42003-020-0844-1.
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De Spiegeleer, A;
Bronselaer, A;
Teo, JT;
Byttebier, G;
De Tre, G;
Belmans, L;
Dobson, R;
... De Spiegeleer, B; + view all
(2020)
The Effects of ARBs, ACEis, and Statins on Clinical Outcomes of COVID-19 Infection Among Nursing Home Residents.
Journal of the American Medical Directors Association
, 21
(7)
909-914.e2.
10.1016/j.jamda.2020.06.018.
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De Waal, GM;
De Villiers, WJS;
Forgan, T;
Roberts, T;
Pretorius, E;
(2020)
Colorectal cancer is associated with increased circulating lipopolysaccharide, inflammation and hypercoagulability.
Scientific Reports
, 10
, Article 8777. 10.1038/s41598-020-65324-2.
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Denaxas, S;
Shah, AD;
Mateen, BA;
Kuan, V;
Quint, JK;
Fitzpatrick, N;
Torralbo, A;
... Hemingway, H; + view all
(2020)
A semi-supervised approach for rapidly creating clinical biomarker phenotypes in the UK Biobank using different primary care EHR and clinical terminology systems.
JAMIA Open
, Article ooaa047. 10.1093/jamiaopen/ooaa047.
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Dennis, JM;
Mateen, BA;
Sonabend, R;
Thomas, NJ;
Patel, KA;
Hattersley, AT;
Denaxas, S;
... Vollmer, SJ; + view all
(2020)
Type 2 Diabetes and COVID-19–Related Mortality in the Critical Care Setting: A National Cohort Study in England, March–July 2020.
Diabetes Care
10.2337/dc20-1444.
(In press).
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Dickerman, BA;
García-Albéniz, X;
Logan, RW;
Denaxas, S;
Hernán, MA;
(2020)
Emulating a target trial in case-control designs: an application to statins and colorectal cancer.
International Journal of Epidemiology
, 49
(5)
pp. 1637-1646.
10.1093/ije/dyaa144.
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E
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Eyre, MT;
Burns, R;
Kirkby, V;
Smith, C;
Denaxas, S;
Nguyen, V;
Hayward, A;
... Aldridge, RW; + view all
(2020)
Impact of baseline cases of cough and fever on UK COVID-19 diagnostic testing rates: estimates from the Bug Watch community cohort study [version 1; peer review: 1 approved, 1 approved with reservations].
Wellcome Open Research
, 5
p. 225.
10.12688/wellcomeopenres.16304.1.
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G
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Gale, R;
Gill, C;
Pikoula, M;
Lee, AY;
Hanson, RLW;
Denaxas, S;
Egan, C;
... UK EMR Database Users Group; + view all
(2020)
Multicentre study of 4626 patients assesses the effectiveness, safety and burden of two categories of treatments for central retinal vein occlusion: intravitreal anti-vascular endothelial growth factor injections and intravitreal Ozurdex injections.
British Journal of Ophthalmology
10.1136/bjophthalmol-2020-317306.
(In press).
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Gale, R;
Pikoula, M;
Lee, AY;
Denaxas, S;
Egan, C;
Tufail, A;
Taylor, P;
(2020)
Real world evidence on 5661 patients treated for macular oedema secondary to branch retinal vein occlusion with intravitreal anti-vascular endothelial growth factor, intravitreal dexamethasone or macular laser.
British Journal of Ophthalmology
10.1136/bjophthalmol-2020-315836.
(In press).
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García-González, J;
Brock, AJ;
Parker, MO;
Riley, RJ;
Joliffe, D;
Sudwarts, A;
Teh, M-T;
... Brennan, CH; + view all
(2020)
Identification of slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour.
eLife
, 9
, Article e51295. 10.7554/eLife.51295.
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GBD 2019 Demographics Collaborators;
(2020)
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019.
The Lancet
, 396
(10258)
pp. 1160-1203.
10.1016/S0140-6736(20)30977-6.
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GBD 2019 Diseases and Injuries Collaborators;
(2020)
Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.
The Lancet
, 396
(10258)
pp. 1204-1222.
10.1016/S0140-6736(20)30925-9.
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GBD 2019 Risk Factors Collaborators;
(2020)
Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.
The Lancet
, 396
(10258)
pp. 1223-1249.
10.1016/S0140-6736(20)30752-2.
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GBD Chronic Kidney Disease Collaboration;
(2020)
Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
Lancet
, 395
(10225)
pp. 709-733.
10.1016/S0140-6736(20)30045-3.
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Gkotsis, G;
Mueller, C;
Dobson, RJB;
Hubbard, TJP;
Dutta, R;
(2020)
Mining Social Media Data to Study the Consequences of Dementia Diagnosis on Caregivers and Relatives.
Dementia and Geriatric Cognitive Disorders
, 49
(3)
pp. 295-302.
10.1159/000509123.
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H
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Helbig, I;
Barcia, G;
Pendziwiat, M;
Ganesan, S;
Mueller, SH;
Helbig, KL;
Vaidiswaran, P;
... Nabbout, R; + view all
(2020)
Whole-exome and HLA sequencing in Febrile infection-related epilepsy syndrome.
Annals of Clinical and Translational Neurology
10.1002/acn3.51062.
(In press).
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Hemingway, H;
Lyons, R;
Li, Q;
Buchan, I;
Ainsworth, J;
Pell, J;
Morris, A;
(2020)
A national initiative in data science for health: An evaluation of the UK Farr Institute.
International Journal of Population Data Science
, 5
(1)
10.23889/ijpds.v5i1.1128.
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Hong, S;
Prokopenko, D;
Dobricic, V;
Kilpert, F;
Bos, I;
Vos, SJB;
Tijms, BM;
... Bertram, L; + view all
(2020)
Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset.
Translational Psychiatry
, 10
, Article 403. 10.1038/s41398-020-01074-z.
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Hopfner, F;
Mueller, SH;
Szymczak, S;
Junge, O;
Tittmann, L;
May, S;
Lohmann, K;
... Kuhlenbäumer, G; + view all
(2020)
Rare Variants in Specific Lysosomal Genes Are Associated with Parkinson's Disease.
Movement Disorders
10.1002/mds.28037.
(In press).
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Howe, LJ;
Dudbridge, F;
Schmidt, AF;
Finan, C;
Denaxas, S;
Asselbergs, FW;
Hingorani, AD;
(2020)
Polygenic risk scores for coronary artery disease and subsequent event risk amongst established cases.
Human Molecular Genetics
10.1093/hmg/ddaa052.
(In press).
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I
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Iacoangeli, A;
Lin, T;
Al Khleifat, A;
Jones, AR;
Opie-Martin, S;
Coleman, JRI;
Shatunov, A;
... Al-Chalabi, A; + view all
(2020)
Genome-wide Meta-analysis Finds the ACSL5-ZDHHC6 Locus Is Associated with ALS and Links Weight Loss to the Disease Genetics.
Cell Reports
, 33
(4)
, Article 108323. 10.1016/j.celrep.2020.108323.
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Ibrahim, Z;
Wu, H;
Dobson, R;
(2020)
Modeling rare interactions in time series data through qualitative change: Application to outcome prediction in intensive care units.
In:
Frontiers in Artificial Intelligence and Applications.
(pp. pp. 1826-1833).
IOS Press
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Ibrahim, ZM;
Wu, H;
Hamoud, A;
Stappen, L;
Dobson, RJB;
Agarossi, A;
(2020)
On classifying sepsis heterogeneity in the ICU: insight using machine learning.
Journal of the American Medical Informatics Association
, 27
(3)
pp. 437-443.
10.1093/jamia/ocz211.
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Iqbal, E;
Govind, R;
Romero, A;
Dzahini, O;
Broadbent, M;
Stewart, R;
Smith, T;
... Ibrahim, ZM; + view all
(2020)
The side effect profile of Clozapine in real world data of three large mental health hospitals.
PLoS One
, 15
(12)
, Article e0243437. 10.1371/journal.pone.0243437.
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J
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Jones, KH;
Ford, EM;
Lea, N;
Griffiths, L;
Hassan, L;
Heys, S;
Squires, E;
(2020)
Towards the development of data governance standards for using clinical free-text data in health research: a position paper.
Journal of Medical Internet Research
, 22
(6)
, Article e16760. 10.2196/16760.
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K
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Karpinskyj, C;
Burnell, M;
Gonzalez-Izquierdo, A;
Ryan, A;
Kalsi, J;
Jacobs, I;
Parmar, M;
... Gentry-Maharaj, A; + view all
(2020)
Socioeconomic Status and Ovarian Cancer Stage at Diagnosis: A Study Nested Within UKCTOCS.
Diagnostics
, 10
(2)
, Article 89. 10.3390/diagnostics10020089.
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Katsoulis, M;
Gomes, M;
Bamia, C;
(2020)
Moving from two- to multi-way interactions among binary risk factors on the additive scale.
Biostatistics & Epidemiology
, 4
(1)
pp. 282-293.
10.1080/24709360.2020.1850171.
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Katsoulis, M;
Gomes, M;
Lai, AG;
Henry, A;
Denaxas, S;
Lagiou, P;
Nafilyan, V;
... Lumbers, RT; + view all
(2020)
Estimating the effect of reduced attendance at emergency departments for suspected cardiac conditions on cardiac mortality during the COVID-19 pandemic.
Circulation: Cardiovascular Quality and Outcomes
10.1161/CIRCOUTCOMES.120.007085.
(In press).
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Katsoulis, M;
Lai, AG;
Kipourou, D-K;
Sofat, R;
Gomes, M;
Banerjee, A;
Denaxas, S;
... Diaz-Ordaz, K; + view all
(2020)
How to estimate the association between change in a risk factor and a health outcome?
ArXiv
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Kuan Po Ai, Valerie;
(2020)
Exploring the relationship between age and health conditions using electronic health records: from single diseases to multimorbidities.
Doctoral thesis (Ph.D), UCL (University College London).
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Kugathasan, P;
Wu, H;
Gaughran, F;
Nielsen, RE;
Pritchard, M;
Dobson, R;
Stewart, R;
(2020)
Association of physical health multimorbidity with mortality in people with schizophrenia spectrum disorders: Using a novel semantic search system that captures physical diseases in electronic patient records.
Schizophrenia Research
, 216
pp. 408-415.
10.1016/j.schres.2019.10.061.
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L
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Lai, AG;
Pasea, L;
Banerjee, A;
Hall, G;
Denaxas, S;
Chang, WH;
Katsoulis, M;
... Hemingway, H; + view all
(2020)
Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study.
BMJ Open
, 10
(11)
, Article e043828. 10.1136/bmjopen-2020-043828.
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Lewer, D;
Padmanathan, P;
Qummer ul Arfeen, M;
Denaxas, S;
Forbes, H;
Gonzalez-Izquierdo, A;
Hickman, M;
(2020)
Healthcare use by people who use illicit opioids (HUPIO): development of a cohort based on electronic primary care records in England [version 1; peer review: 2 approved].
Wellcome Open Research
, 5
, Article 282. 10.12688/wellcomeopenres.16431.1.
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Lhatoo, SD;
Bernasconi, N;
Blumcke, I;
Braun, K;
Buchhalter, J;
Denaxas, S;
Galanopoulou, A;
... Wiebe, S; + view all
(2020)
Big data in epilepsy: Clinical and research considerations. Report from the Epilepsy Big Data Task Force of the International League Against Epilepsy.
Epilepsia
, 61
(9)
pp. 1869-1883.
10.1111/epi.16633.
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Liao, C;
Sarayloo, F;
Rochefort, D;
Houle, G;
Akçimen, F;
He, Q;
Laporte, AD;
... Rouleau, GA; + view all
(2020)
Multiomics Analyses Identify Genes and Pathways Relevant to Essential Tremor.
Movement Disorders
10.1002/mds.28031.
(In press).
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M
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Martin, TC;
Ilieva, KM;
Visconti, A;
Beaumont, M;
Kiddle, SJ;
Dobson, RJB;
Mangino, M;
... Karagiannis, SN; + view all
(2020)
Dysregulated Antibody, Natural Killer Cell and Immune Mediator Profiles in Autoimmune Thyroid Diseases.
Cells
, 9
(3)
, Article 665. 10.3390/cells9030665.
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Mateen, BA;
David, AL;
Denaxas, S;
(2020)
Electronic Health Records to Predict Gestational Diabetes Risk.
Trends in Pharmacological Sciences
, 41
(5)
pp. 301-304.
10.1016/j.tips.2020.03.003.
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N
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NCD Risk Factor Collaboration (NCD-RisC), .;
(2020)
Repositioning of the global epicentre of non-optimal cholesterol.
Nature
, 582
(7810)
pp. 73-77.
10.1038/s41586-020-2338-1.
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O
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Oliver, D;
Spada, G;
Colling, C;
Broadbent, M;
Baldwin, H;
Patel, R;
Stewart, R;
... Fusar-Poli, P; + view all
(2020)
Real-world implementation of precision psychiatry: Transdiagnostic risk calculator for the automatic detection of individuals at-risk of psychosis.
Schizophrenia Research
10.1016/j.schres.2020.05.007.
(In press).
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P
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Patel, H;
Iniesta, R;
Stahl, D;
Dobson, RJB;
Newhouse, SJ;
(2020)
Working Towards a Blood-Derived Gene Expression Biomarker Specific for Alzheimer's Disease.
Journal of Alzheimer's Disease,
10.3233/JAD-191163.
(In press).
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Pathak, N;
Patel, P;
Burns, R;
Haim, L;
Zhang, CX;
Boukari, Y;
Gonzales-Izquierdo, A;
... Aldridge, RW; + view all
(2020)
Healthcare resource utilisation and mortality outcomes in international migrants to the UK: analysis protocol for a linked population-based cohort study using Clinical Practice Research Datalink (CPRD), Hospital Episode Statistics (HES) and the Office for National Statistics (ONS) [version 1; peer review: awaiting peer review].
Wellcome Open Research
, 5
, Article 156. 10.12688/wellcomeopenres.15931.1.
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Phadke, R;
Hedberg-Oldfors, C;
Scalco, RS;
Lowe, DM;
Ashworth, M;
Novelli, M;
Vara, R;
... Murphy, E; + view all
(2020)
RBCK1‐related disease: A rare multisystem disorder with polyglucosan storage, auto‐inflammation, recurrent infections, skeletal, and cardiac myopathy—Four additional patients and a review of the current literature.
Journal of Inherited Metabolic Disease
, 43
(5)
pp. 1002-1013.
10.1002/jimd.12234.
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Planell-Morell, P;
Bajekal, M;
Denaxas, S;
Raine, R;
Alexander, DC;
(2020)
Trajectories of Disease Accumulation Using Electronic Health Records.
Studies in Health Technology and Informatics
, 270
pp. 469-473.
10.3233/SHTI200204.
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Polhemus, AM;
Novák, J;
Ferrao, J;
Simblett, S;
Radaelli, M;
Locatelli, P;
Matcham, F;
... Hotopf, M; + view all
(2020)
Human-Centered Design Strategies for Device Selection in mHealth Programs: Development of a Novel Framework and Case Study.
JMIR mHealth uHealth
, 8
(5)
, Article e16043. 10.2196/16043.
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R
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Roth, GA;
Mensah, GA;
Johnson, CO;
Addolorato, G;
Ammirati, E;
Baddour, LM;
Barengo, NC;
... GBD-NHLBI-JACC Global Burden of Cardiovascular Diseases Writing; + view all
(2020)
Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019: Update From the GBD 2019 Study.
Journal of the American College of Cardiology
, 76
(25)
pp. 2982-3021.
10.1016/j.jacc.2020.11.010.
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S
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Samanta, S;
O’Hagan, S;
Swainston, N;
Roberts, TJ;
Kell, DB;
(2020)
VAE-Sim: A Novel Molecular Similarity Measure Based on a Variational Autoencoder.
Molecules
, 25
(15)
, Article 3446. 10.3390/molecules25153446.
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Saxby, K;
Sanghvi, S;
Bodalia, PN;
Ferner, RE;
Leandro, M;
Urquhart, R;
Sofat, R;
(2020)
A novel approach to support implementation of biosimilars within a UK tertiary hospital.
British Journal of Clinical Pharmacology
, 86
(1)
pp. 23-28.
10.1111/bcp.14150.
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Scully, PR;
Patel, KP;
Treibel, TA;
Thornton, GD;
Hughes, RK;
Chadalavada, S;
Katsoulis, M;
... Moon, JC; + view all
(2020)
Prevalence and outcome of dual aortic stenosis and cardiac amyloid pathology in patients referred for transcatheter aortic valve implantation.
European Heart Journal
10.1093/eurheartj/ehaa170.
(In press).
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Searle, T;
Ibrahim, Z;
Dobson, R;
(2020)
Comparing natural language processing techniques for Alzheimer's dementia prediction in spontaneous speech.
In:
(Proceedings) INTERSPEECH 2020.
(pp. pp. 2192-2196).
International Speech Communication Association
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Searle, T;
Ibrahim, Z;
Dobson, RJB;
(2020)
Experimental Evaluation and Development of a Silver-Standard for the MIMIC-III Clinical Coding Dataset.
In:
Proceedings of the 19th SIGBioMed Workshop on Biomedical Language Processing.
(pp. pp. 76-85).
Association for Computational Linguistics (ACL): Online.
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Searle, T;
Kraljevic, Z;
Bendayan, R;
Bean, D;
Dobson, R;
(2020)
MedCATTrainer: A biomedical free text annotation interface with active learning and research use case specific customisation.
In:
Proceedings of the 2019 Conference on Empirical Methods in Natural Language Processing and the 9th International Joint Conference on Natural Language Processing (EMNLP-IJCNLP): System Demonstrations.
(pp. pp. 139-144).
Association for Computational Linguistics: Hong Kong, China.
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Sepanlou, SG;
Safiri, S;
Bisignano, C;
Ikuta, KS;
Merat, S;
Saberifiroozi, M;
Poustchi, H;
... Malekzadeh, R; + view all
(2020)
The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
The Lancet Gastroenterology and Hepatology
, 5
(3)
pp. 245-266.
10.1016/S2468-1253(19)30349-8.
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Shah, S;
Henry, A;
Roselli, C;
Lin, H;
Sveinbjörnsson, G;
Fatemifar, G;
Hedman, ÅK;
... Lumbers, RT; + view all
(2020)
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
Nature Communications
, 11
, Article 163. 10.1038/s41467-019-13690-5.
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Shi, L;
Winchester, LM;
Liu, BY;
Killick, R;
Ribe, EM;
Westwood, S;
Baird, AL;
... Lovestone, S; + view all
(2020)
Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology.
Journal of Alzheimer's Disease
, 77
(3)
pp. 1353-1368.
10.3233/JAD-200208.
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