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Number of items: 43.
Article
Anandagoda, N;
Willis, JC;
Hertweck, A;
Roberts, LB;
Jackson, I;
Gökmen, MR;
Jenner, RG;
... Lord, GM; + view all
(2019)
microRNA-142-mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance.
Journal of Clinical Investigation
10.1172/JCI124725.
(In press).
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Barrington, C;
Georgopoulou, D;
Pezic, D;
Varsally, W;
Herrero, J;
Hadjur, S;
(2019)
Enhancer accessibility and CTCF occupancy underlie asymmetric TAD architecture and cell type specific genome topology.
Nature Communications
, 10
, Article 2908. 10.1038/s41467-019-10725-9.
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Bell, CG;
Lowe, R;
Adams, PD;
Baccarelli, AA;
Beck, S;
Bell, JT;
Christensen, BC;
... Rakyan, VK; + view all
(2019)
DNA methylation aging clocks: challenges and recommendations.
Genome Biology
, 20
, Article 249. 10.1186/s13059-019-1824-y.
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Beltran, M;
Tavares, M;
Justin, N;
Khandelwal, G;
Ambrose, J;
Foster, BM;
Worlock, KB;
... Jenner, RG; + view all
(2019)
G-tract RNA removes Polycomb repressive complex 2 from genes.
Nature Structural & Molecular Biology
, 26
pp. 899-909.
10.1038/s41594-019-0293-z.
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Biswas, D;
Birkbak, NJ;
Rosenthal, R;
Hiley, CT;
Lim, EL;
Papp, K;
Boeing, S;
... TRACERx Consortium; + view all
(2019)
A clonal expression biomarker associates with lung cancer mortality.
Nature Medicine
, 25
pp. 1540-1548.
10.1038/s41591-019-0595-z.
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Boned Del Río, I;
Young, LC;
Sari, S;
Jones, GG;
Ringham-Terry, B;
Hartig, N;
Rejnowicz, E;
... Rodriguez-Viciana, P; + view all
(2019)
SHOC2 complex-driven RAF dimerization selectively contributes to ERK pathway dynamics.
Proceedings of the National Academy of Sciences of the United States of America
10.1073/pnas.1902658116.
(In press).
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Breeze, CE;
Reynolds, AP;
van Dongen, J;
Dunham, I;
Lazar, J;
Neph, S;
Vierstra, J;
... Beck, S; + view all
(2019)
eFORGE v2.0: updated analysis of cell type-specific signal in epigenomic data.
Bioinformatics
10.1093/bioinformatics/btz456.
(In press).
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Carters, R;
Cheraghchi-Bashi, A;
Westhorpe, A;
Yu, S;
Shanneik, Y;
Seraia, E;
Ouaret, D;
... Sharma, RA; + view all
(2019)
Identification of anticancer drugs to radiosensitise BRAF-wild-type and mutant colorectal cancer.
Cancer Biology & Medicine
, 16
(2)
pp. 234-246.
10.20892/j.issn.2095-3941.2018.0284.
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Chang, J-M;
Floden, EW;
Herrero, J;
Gascuel, O;
Di Tommaso, P;
Notredame, C;
(2019)
Incorporating alignment uncertainty into Felsenstein’s phylogenetic bootstrap to improve its reliability.
Bioinformatics
10.1093/bioinformatics/btz082.
(In press).
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Chen, W;
Morabito, SJ;
Kessenbrock, K;
Enver, T;
Meyer, KB;
Teschendorff, AE;
(2019)
Single-cell landscape in mammary epithelium reveals bipotent-like cells associated with breast cancer risk and outcome.
Communications Biology
, 2
, Article 306. 10.1038/s42003-019-0554-8.
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Chervova, O;
Conde, L;
Guerra-Assunção, JA;
Moghul, I;
Webster, AP;
Berner, A;
Larose Cadieux, E;
... Beck, S; + view all
(2019)
The Personal Genome Project-UK, an open access resource of human multi-omics data.
Scientific Data
, 6
, Article 257. 10.1038/s41597-019-0205-4.
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Conesa, A;
Beck, S;
(2019)
Making multi-omics data accessible to researchers.
[Editorial comment].
Scientific Data
, 6
(1)
, Article 251. 10.1038/s41597-019-0258-4.
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Dyke, SOM;
Saulnier, KM;
Dupras, C;
Webster, AP;
Maschke, K;
Rothstein, M;
Siebert, R;
... Joly, Y; + view all
(2019)
Points-to-consider on the return of results in epigenetic research.
Genome Medicine
, 11
(1)
, Article 31. 10.1186/s13073-019-0646-6.
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Ecker, S;
Beck, S;
(2019)
The epigenetic clock: a molecular crystal ball for human aging?
Aging (Albany NY)
, 11
(2)
pp. 833-835.
10.18632/aging/101712.
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Ferrer, IR;
West, HC;
Henderson, S;
Ushakov, DS;
Santos E Sousa, P;
Strid, J;
Chakraverty, R;
... Bennett, CL; + view all
(2019)
A wave of monocytes is recruited to replenish the long-term Langerhans cell network after immune injury.
Science Immunology
, 4
(38)
, Article eaax8704. 10.1126/sciimmunol.aax8704.
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Fujimitsu, K;
Yamano, H;
(2019)
PP2A-B56 binds to Apc1 and promotes Cdc20 association with the APC/C ubiquitin ligase in mitosis.
EMBO Reports
, Article e48503. 10.15252/embr.201948503.
(In press).
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Huettenhain, R;
Choi, M;
de la Fuente, LM;
Oehl, K;
Chang, C-YV;
Zimmermann, A-K;
Malander, S;
... Aebersold, R; + view all
(2019)
A Targeted Mass Spectrometry Strategy for Developing Proteomic Biomarkers: A Case Study of Epithelial Ovarian Cancer.
Molecular & Cellular Proteomics
, 18
(9)
pp. 1836-1850.
10.1074/mcp.RA118.001221.
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Jones, GG;
Del Río, IB;
Sari, S;
Sekerim, A;
Young, LC;
Hartig, N;
Areso Zubiaur, I;
... Rodriguez-Viciana, P; + view all
(2019)
SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers.
Nature Communications
, 10
(1)
, Article 2532. 10.1038/s41467-019-10367-x.
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Joshi, K;
Robert de Massy, M;
Ismail, M;
Reading, JL;
Uddin, I;
Woolston, A;
Hatipoglu, E;
... Chain, B; + view all
(2019)
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Nature Medicine
, 25
pp. 1549-1559.
10.1038/s41591-019-0592-2.
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Kataria, M;
Yamano, H;
(2019)
Interplay between Phosphatases and the Anaphase-Promoting Complex/Cyclosome in Mitosis.
MDPI — Cells
, 8
(8)
, Article 814. 10.3390/cells8080814.
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Krishna-Subramanian, S;
Singer, S;
Armaka, M;
Banales, JM;
Holzer, K;
Schirmacher, P;
Walczak, H;
... Kondylis, V; + view all
(2019)
RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury.
Cell Death & Differentiation
10.1038/s41418-019-0330-9.
(In press).
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Kular, L;
Needhamsen, M;
Adzemovic, MZ;
Kramarova, T;
Gomez-Cabrero, D;
Ewing, E;
Piket, E;
... Jagodic, M; + view all
(2019)
Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis.
Clinical Epigenetics
, 11
(1)
, Article 86. 10.1186/s13148-019-0678-1.
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Lechner, M;
Breeze, CE;
O'Mahony, JF;
Masterson, L;
(2019)
Early detection of HPV-associated oropharyngeal cancer.
[Letter].
Lancet
, 393
(10186)
p. 2123.
10.1016/S0140-6736(19)30227-2.
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Lechner, M;
Jones, OS;
Breeze, CE;
Gilson, R;
(2019)
Gender-neutral HPV vaccination in the UK, rising male oropharyngeal cancer rates, and lack of HPV awareness.
[Letter].
Lancet Infectious Diseases
, 19
(2)
pp. 131-132.
10.1016/S1473-3099(18)30802-8.
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Marioni, RE;
Suderman, M;
Chen, BH;
Horvath, S;
Bandinelli, S;
Morris, T;
Beck, S;
... Hägg, S; + view all
(2019)
Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data.
The Journals of Gerontology: Series A
, 74
(1)
pp. 57-61.
10.1093/gerona/gly060.
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Meijles, DN;
Zoumpoulidou, G;
Markou, T;
Rostron, KA;
Patel, R;
Lay, K;
Handa, BS;
... Clerk, A; + view all
(2019)
The cardiomyocyte “redox rheostat”: Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death.
Journal of Molecular and Cellular Cardiology
, 129
pp. 118-129.
10.1016/j.yjmcc.2019.02.006.
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Moore, A;
Kane, E;
Wang, Z;
Panagiotou, OA;
Teras, LR;
Monnereau, A;
Wong Doo, N;
... Berndt, SI; + view all
(2019)
Genetically Determined Height and Risk of Non-hodgkin Lymphoma.
Frontiers in Oncology
, 9
, Article 1539. 10.3389/fonc.2019.01539.
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Nguyen, HP;
Stewart, S;
Kukwikila, MN;
Jones, SF;
Offenbartl-Stiegert, D;
Mao, S;
Balasubramanian, S;
... Howorka, S; + view all
(2019)
A Photo‐responsive Small‐Molecule Approach for the Opto‐epigenetic Modulation of DNA Methylation.
Angewandte Chemie: International Edition
, 58
(20)
pp. 6620-6624.
10.1002/anie.201901139.
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Ometto, G;
Moghul, I;
Montesano, G;
Hunter, A;
Pontikos, N;
Jones, P;
Keane, P;
... Crabb, D; + view all
(2019)
ReLayer: a free, online tool for extracting retinal thickness from cross-platform OCT images.
Translational Vision Science and Technology
, 8
(3)
, Article 25. 10.1167/tvst.8.3.25.
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Peltzer, N;
Walczak, H;
(2019)
Cell Death and Inflammation - A Vital but Dangerous Liaison.
Trends in Immunology
, 40
(5)
pp. 387-402.
10.1016/j.it.2019.03.006.
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Peltzer, N;
Walczak, H;
(2019)
Endothelial Cell Killing by TAK1 Inhibition: A Novel Anti-angiogenic Strategy in Cancer Therapy.
Developmental Cell
, 48
(2)
pp. 127-128.
10.1016/j.devcel.2019.01.011.
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Priyann, A;
Woodcroft, BJ;
Rai, V;
Moghul, I;
Munagala, A;
Ter, F;
Chowdhary, H;
... Wurm, Y; + view all
(2019)
Sequenceserver: A Modern Graphical User Interface for Custom BLAST Databases.
Molecular Biology and Evolution
, 36
(12)
pp. 2922-2924.
10.1093/molbev/msz185.
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Rosenthal, R;
Cadieux, EL;
Salgado, R;
Bakir, MA;
Moore, DA;
Hiley, CT;
Lund, T;
... TRACERx consortium; + view all
(2019)
Neoantigen-directed immune escape in lung cancer evolution.
Nature
10.1038/s41586-019-1032-7.
(In press).
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Saint, M;
Bertaux, F;
Tang, W;
Sun, X-M;
Game, L;
Köferle, A;
Bähler, J;
... Marguerat, S; + view all
(2019)
Single-cell imaging and RNA sequencing reveal patterns of gene expression heterogeneity during fission yeast growth and adaptation.
Nature Microbiology
, 4
(3)
pp. 480-491.
10.1038/s41564-018-0330-4.
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Saulnier, KM;
Bujold, D;
Dyke, SOM;
Dupras, C;
Beck, S;
Bourque, G;
Joly, Y;
(2019)
Benefits and barriers in the design of harmonized access agreements for international data sharing.
Scientific Data
, 6
, Article 297. 10.1038/s41597-019-0310-4.
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Spit, M;
Rieser, E;
Walczak, H;
(2019)
Linear ubiquitination at a glance.
Journal of Cell Science
, 132
(2)
, Article jcs208512. 10.1242/jcs.208512.
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Steele, CD;
Tarabichi, M;
Oukrif, D;
Webster, AP;
Ye, H;
Fittall, M;
Lombard, P;
... Pillay, N; + view all
(2019)
Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways.
Cancer Cell
, 35
(3)
441-456.e8.
10.1016/j.ccell.2019.02.002.
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Teixeira, VH;
Pipinikas, CP;
Pennycuick, A;
Lee-Six, H;
Chandrasekharan, D;
Beane, J;
Morris, TJ;
... Janes, SM; + view all
(2019)
Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions.
Nature Medicine
, 25
pp. 517-525.
10.1038/s41591-018-0323-0.
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Yamano, H;
(2019)
APC/C: current understanding and future perspectives.
F1000Research
, 8
, Article 725. 10.12688/f1000research.18582.1.
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Zhang, C;
Stockwell, SR;
Elbanna, M;
Ketteler, R;
Freeman, J;
Al-Lazikani, B;
Eccles, S;
... Mittnacht, S; + view all
(2019)
Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases.
Oncogene
, 38
pp. 5905-5920.
10.1038/s41388-019-0850-2.
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Zheng, SC;
Breeze, CE;
Beck, S;
Dong, D;
Zhu, T;
Ma, L;
Ye, W;
... Teschendorff, AE; + view all
(2019)
EpiDISH web server: Epigenetic Dissection of Intra-Sample-Heterogeneity with online GUI.
Bioinformatics
10.1093/bioinformatics/btz833.
(In press).
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Zhou, L;
Ng, HK;
Drautz-Moses, DI;
Schuster, SC;
Beck, S;
Kim, C;
Chambers, JC;
(2019)
Systematic evaluation of library preparation methods and sequencing platforms for high-throughput whole genome bisulfite sequencing.
Scientific Reports
, 9
, Article 10383. 10.1038/s41598-019-46875-5.
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Thesis
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Boned del Río, Isabel;
(2019)
Therapeutic potential of SHOC2 via its selective contribution of the ERK pathway activation.
Doctoral thesis (Ph.D), UCL (University College London).
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