Browse by UCL Departments and Centres
Group by: Author | Type
Number of items: 102.
Article
(2016)
The biotechnological potential of Nannochloropsis.
Perspectives in Phycology
10.1127/pip/2016/0065.
|
Abedini, A;
Plesner, A;
Cao, P;
Ridgway, Z;
Zhang, J;
Tu, L-H;
Middleton, CT;
... Schmidt, AM; + view all
(2016)
Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics.
eLife
, 5
, Article e12977. 10.7554/eLife.12977.
|
Ahn, M;
Hagan, CL;
Bernardo-Gancedo, A;
De Genst, E;
Newby, FN;
Christodoulou, J;
Dhulesia, A;
... Kumita, JR; + view all
(2016)
The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme.
Biophysical Journal
, 111
(11)
pp. 2358-2367.
10.1016/j.bpj.2016.10.028.
|
Al-Haj, L;
Lui, YT;
Abed, RM;
Gomaa, MA;
Purton, S;
(2016)
Cyanobacteria as Chassis for Industrial Biotechnology: Progress and Prospects.
Life
, 6
(4)
, Article 42. 10.3390/life6040042.
|
Al-Numair, NS;
Lopes, L;
Syrris, P;
Monserrat, L;
Elliott, P;
Martin, AC;
(2016)
The structural effects of mutations can aid in differential phenotype prediction of beta-myosin heavy chain (Myosin-7) missense variants.
Bioinformatics
, 32
(19)
pp. 2947-2955.
10.1093/bioinformatics/btw362.
|
Ashford, P;
Hernandez, A;
Greco, TM;
Buch, A;
Sodeik, B;
Cristea, IM;
Grünewald, K;
... Topf, M; + view all
(2016)
HVint: A Strategy for Identifying Novel Protein-Protein Interactions in Herpes Simplex Virus Type 1.
Molecular & Cellular Proteomics
, 15
(9)
pp. 2939-2953.
10.1074/mcp.M116.058552.
|
Ball, NJ;
Nicastro, G;
Dutta, M;
Pollard, DJ;
Goldstone, DC;
Sanz-Ramos, M;
Ramos, A;
... Taylor, IA; + view all
(2016)
Structure of a Spumaretrovirus Gag Central Domain Reveals an Ancient Retroviral Capsid.
PLOS Pathogens
, 12
(11)
, Article e1005981. 10.1371/journal.ppat.1005981.
|
Bartlett, MJ;
Shephard, EA;
(2016)
The integration and interpretation of pharmacogenomics. A comparative study between the United States of America and Europe: towards better health care.
Drug Metabolism and Personalized Therapy
, 31
(2)
pp. 91-96.
10.1515/dmpt-2015-0044.
|
Bayele, HK;
Debnam, ES;
Srai, KS;
(2016)
Nrf2 transcriptional derepression from Keap1 by dietary polyphenols.
Biochemical and Biophysical Research Communications
, 469
(3)
pp. 521-528.
10.1016/j.bbrc.2015.11.103.
|
Blombach, F;
Smollett, KL;
Grohmann, D;
Werner, F;
(2016)
Molecular Mechanisms of Transcription Initiation-Structure, Function, and Evolution of TFE/TFIIE-Like Factors and Open Complex Formation.
Journal of Molecular Biology
, 428
(12)
pp. 2592-2606.
10.1016/j.jmb.2016.04.016.
|
Broncel, M;
Serwa, RA;
Bunney, TD;
Katan, M;
Tate, EW;
(2016)
Global Profiling of Huntingtin-associated protein E (HYPE)-Mediated AMPylation through a Chemical Proteomic Approach.
Molecular & Cellular Proteomics
, 15
(2)
pp. 715-725.
10.1074/mcp.O115.054429.
|
Bullock, JMA;
Schwab, J;
Thalassinos, K;
Topf, M;
(2016)
The Importance of Non-accessible Crosslinks and Solvent Accessible Surface Distance in Modeling Proteins with Restraints From Crosslinking Mass Spectrometry.
Molecular & Cellular Proteomics
, 15
(7)
pp. 2491-2500.
10.1074/mcp.M116.058560.
|
Cabrita, LD;
Cassaignau, AM;
Launay, HM;
Waudby, CA;
Wlodarski, T;
Camilloni, C;
Karyadi, ME;
... Christodoulou, J; + view all
(2016)
A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding.
Nature Structural and Molecular Biology
, 23
(4)
pp. 278-285.
10.1038/nsmb.3182.
|
Cassaignau, AM;
Launay, HM;
Karyadi, ME;
Wang, X;
Waudby, CA;
Deckert, A;
Robertson, AL;
... Cabrita, LD; + view all
(2016)
A strategy for co-translational folding studies of ribosome-bound nascent chain complexes using NMR spectroscopy.
Nature Protocols
, 11
(8)
pp. 1492-1507.
10.1038/nprot.2016.101.
|
Cheverton, AM;
Gollan, B;
Przydacz, M;
Wong, CT;
Mylona, A;
Hare, SA;
Helaine, S;
(2016)
A Salmonella Toxin Promotes Persister Formation through Acetylation of tRNA.
Molecular Cell
, 63
(1)
pp. 86-96.
10.1016/j.molcel.2016.05.002.
|
Chichger, H;
Cleasby, M;
Srai, S;
Unwin, R;
Debnam, E;
Marks, J;
(2016)
Experimental type II diabetes and related models of impaired glucose metabolism differentially regulate glucose transporters at the proximal tubule brush border membrane.
Experimental Physiology
, 101
(6)
pp. 731-742.
10.1113/EP085670.
|
Costa, TR;
Ilangovan, A;
Ukleja, M;
Redzej, A;
Santini, JM;
Smith, TK;
Egelman, EH;
(2016)
Structure of the Bacterial Sex F Pilus Reveals an Assembly of a Stoichiometric Protein-Phospholipid Complex.
Cell
, 166
(6)
1436-1444.e10.
10.1016/j.cell.2016.08.025.
|
Das, S;
Orengo, CA;
(2016)
Protein function annotation using protein domain family resources.
Methods
, 93
pp. 24-34.
10.1016/j.ymeth.2015.09.029.
|
Davies, HM;
Thalassinos, K;
Osborne, AR;
(2016)
Expansion of Lysine-rich Repeats in Plasmodium Proteins Generates Novel Localisation Sequences that Target the Periphery of the Host Erythrocyte.
Journal of Biological Chemistry
, 291
(50)
pp. 26188-26207.
10.1074/jbc.M116.761213.
|
Deckert, A;
Waudby, CA;
Wlodarski, T;
Wentink, AS;
Wang, X;
Kirkpatrick, JP;
Paton, JF;
... Christodoulou, J; + view all
(2016)
Structural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factor.
Proceedings of the National Academy of Sciences of the United States of America
, 113
(18)
pp. 5012-5017.
10.1073/pnas.1519124113.
|
Dekker, L;
Arsène-Ploetze, F;
Santini, JM;
(2016)
Comparative proteomics of Acidithiobacillus ferrooxidans grown in the presence and absence of uranium.
Research in Microbiology
, 167
(3)
pp. 234-239.
10.1016/j.resmic.2016.01.007.
|
Densham, RM;
Garvin, AJ;
Stone, HR;
Strachan, J;
Baldock, RA;
Daza-Martin, M;
Fletcher, A;
... Morris, JR; + view all
(2016)
Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection.
Nature Structural & Molecular Biology
, 23
(7)
pp. 647-655.
10.1038/nsmb.3236.
|
Dona, AC;
Kyriakides, M;
Scott, F;
Shephard, EA;
Varshavi, D;
Veselkov, K;
Everett, JR;
(2016)
A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments.
Computational and Structural Biotechnology Journal
10.1016/j.csbj.2016.02.005.
|
Duval, S;
Santini, JM;
Lemaire, D;
Chaspoul, F;
Russell, MJ;
Grimaldi, S;
Nitschke, W;
(2016)
The H-bond network surrounding the pyranopterins modulates redox cooperativity in the molybdenum-bisPGD cofactor in arsenite oxidase.
Biochimica et Biophysica Acta - Bioenergetics
, 1857
(9)
pp. 1353-1362.
10.1016/j.bbabio.2016.05.003.
|
Ekong, R;
Emmett, W;
Dawson, NL;
Futema, M;
Plagnol, V;
Humphries, SE;
Povey, MS;
(2016)
Variants within TSC2 exons 25 and 31 are very unlikely to cause clinically diagnosable tuberous sclerosis.
Human Mutation
, 37
(4)
pp. 364-370.
10.1002/humu.22951.
|
Farabella, I;
Pham, T;
Henderson, NS;
Geibel, S;
Phan, G;
Thanassi, DG;
Delcour, AH;
... Topf, M; + view all
(2016)
Correction: Allosteric signalling in the outer membrane translocation domain of PapC usher.
eLife
, 5
, Article e21585. 10.7554/eLife.21585.
|
Fennema, D;
Phillips, IR;
Shephard, EA;
(2016)
Trimethylamine and trimethylamine N-oxide, a flavin-containing monooxygenase 3 (FMO3)-mediated host-microbiome metabolic axis implicated in health and disease.
Drug Metabolism and Disposition
, 44
pp. 1839-1850.
10.1124/dmd.116.070615.
|
Finn, RD;
Attwood, TK;
Babbitt, PC;
Bateman, A;
Bork, P;
Bridge, AJ;
Chang, HY;
... Mitchell, AL; + view all
(2016)
InterPro in 2017-beyond protein family and domain annotations.
Nucleic Acids Research
10.1093/nar/gkw1107.
(In press).
|
Fung, KW;
Wright, DW;
Gor, J;
Swann, MJ;
Perkins, SJ;
(2016)
Domain structure of human complement C4b extends with increasing NaCl concentration: implications for its regulatory mechanism.
Biochemical Journal
, 473
(23)
pp. 4473-4491.
10.1042/BCJ20160744.
|
Grassme, KS;
Garza-Garcia, A;
Delgado, J-P;
Godwin, JW;
Kumar, A;
Gates, PB;
Driscoll, PC;
(2016)
Mechanism of Action of Secreted Newt Anterior Gradient Protein.
PLOS One
, 11
(4)
, Article e0154176. 10.1371/journal.pone.0154176.
|
Gulbis, JM;
Waksman, G;
(2016)
Editorial overview: Membranes.
Current Opinion in Structural Biology
, 39
vii-ix.
10.1016/j.sbi.2016.09.004.
|
Harvey, DJ;
Scarff, CA;
Edgeworth, M;
Pagel, K;
Thalassinos, K;
Struwe, WB;
Crispin, M;
(2016)
Travelling-wave ion mobility mass spectrometry and negative ion fragmentation of hybrid and complex N-glycans.
Journal of Mass Spectrometry
, 51
(11)
pp. 1064-1079.
10.1002/jms.3828.
|
Harvey, DJ;
Scarff, CA;
Edgeworth, M;
Struwe, WB;
Pagel, K;
Thalassinos, K;
Crispin, M;
(2016)
Travelling-wave ion mobility and negative ion fragmentation of high-mannose N-glycans.
Journal of Mass Spectrometry
, 51
(3)
pp. 219-235.
10.1002/jms.3738.
|
Hodel, AW;
Leung, C;
Dudkina, NV;
Saibil, HR;
Hoogenboom, BW;
(2016)
Atomic force microscopy of membrane pore formation by cholesterol dependent cytolysins.
Current Opinion in Structural Biology
, 39
pp. 8-15.
10.1016/j.sbi.2016.03.005.
|
Hospenthal, MK;
Redzej, A;
Dodson, K;
Ukleja, M;
Frenz, B;
Rodrigues, C;
Hultgren, SJ;
... Waksman, G; + view all
(2016)
Structure of a Chaperone-Usher Pilus Reveals the Molecular Basis of Rod Uncoiling.
Cell
, 164
(1-2)
pp. 269-278.
10.1016/j.cell.2015.11.049.
|
Jeffries, JWE;
Dawson, N;
Orengo, C;
Moody, TS;
Quinn, DJ;
Hailes, HC;
Ward, JM;
(2016)
Metagenome Mining: A Sequence Directed Strategy for the Retrieval of Enzymes for Biocatalysis.
ChemistrySelect
, 1
(10)
pp. 2217-2220.
10.1002/slct.201600515.
|
Jiang, Y;
Oron, TR;
Clark, WT;
Bankapur, AR;
D'Andrea, D;
Lepore, R;
Funk, CS;
... Radivojac, P; + view all
(2016)
An expanded evaluation of protein function prediction methods shows an improvement in accuracy.
Genome Biology
, 17
, Article 184. 10.1186/s13059-016-1037-6.
|
Juen, MA;
Wunderlich, CH;
Nussbaumer, F;
Tollinger, M;
Kontaxis, G;
Konrat, R;
Hansen, DF;
(2016)
Excited States of Nucleic Acids Probed by Proton Relaxation Dispersion NMR Spectroscopy.
Angewandte Chemie International Edition
, 55
(39)
pp. 12008-12012.
10.1002/anie.201605870.
|
Juen, MA;
Wunderlich, CH;
Nußbaumer, F;
Tollinger, M;
Kontaxis, G;
Konrat, R;
Hansen, DF;
(2016)
Excited States of Nucleic Acids Probed by Proton Relaxation Dispersion NMR Spectroscopy.
Angewandte Chemie
, 128
(39)
pp. 12187-12191.
10.1002/ange.201605870.
|
Kazamia, E;
Helliwell, KE;
Purton, S;
Smith, AG;
(2016)
How mutualisms arise in phytoplankton communities: building eco-evolutionary principles for aquatic microbes.
Ecology Letters
, 19
(7)
pp. 810-822.
10.1111/ele.12615.
|
Kearns, S;
Lurz, R;
Orlova, EV;
Okorokov, AL;
(2016)
Two p53 tetramers bind one consensus DNA response element.
Nucleic Acids Research
, 44
(13)
pp. 6185-6199.
10.1093/nar/gkw215.
|
Kimber, JA;
Foreman, L;
Turner, B;
Rich, P;
Kazarian, SG;
(2016)
FTIR spectroscopic imaging and mapping with correcting lenses for studies of biological cells and tissues.
Faraday Discussions
, 187
pp. 69-85.
10.1039/C5FD00158G.
|
King, GA;
Peterman, EJG;
Wuite, GJL;
(2016)
Unravelling the structural plasticity of stretched DNA under torsional constraint.
Nature Communications
, 7
, Article 11810. 10.1038/ncomms11810.
|
Klein, P;
Oloko, M;
Roth, F;
Montel, V;
Malerba, A;
Jarmin, S;
Gidaro, T;
... Trollet, C; + view all
(2016)
Nuclear poly(A)-binding protein aggregates misplace a pre-mRNA outside of SC35 speckle causing its abnormal splicing.
Nucleic Acids Research
, 44
(22)
pp. 10929-10945.
10.1093/nar/gkw703.
|
Kudsiova, L;
Welser, K;
Campbell, F;
Mohammadi, A;
Dawson, N;
Cui, L;
Hailes, HC;
... Tabor, AB; + view all
(2016)
Delivery of siRNA using ternary complexes containing branched cationic peptides: the role of peptide sequence, branching and targeting.
Molecular BioSystems
, 12
(3)
pp. 934-951.
10.1039/c5mb00754b.
|
Kumar, S;
Lockwood, N;
Ramel, MC;
Correia, T;
Ellis, M;
Alexandrov, Y;
Andrews, N;
... French, P; + view all
(2016)
Quantitative in vivo optical tomography of cancer progression & vasculature development in adult zebrafish.
Oncotarget
, 7
(28)
pp. 43939-43948.
10.18632/oncotarget.9756.
|
Lam, SD;
Dawson, NL;
Das, S;
Sillitoe, I;
Ashford, P;
Lee, D;
Lehtinen, S;
... Lees, JG; + view all
(2016)
Gene3D: expanding the utility of domain assignments.
Nucleic Acids Res
, 44
(D1)
D404-D409.
10.1093/nar/gkv1231.
|
Lang, J;
Maréchal, A;
Couture, M;
Santolini, J;
(2016)
Reaction Intermediates and Molecular Mechanism of Peroxynitrite Activation by NO Synthases.
Biophysical Journal
, 111
(10)
pp. 2099-2109.
10.1016/j.bpj.2016.05.056.
|
Lee, D;
Das, S;
Dawson, NL;
Dobrijevic, D;
Ward, J;
Orengo, C;
(2016)
Novel computational protocols for functionally classifying and characterising serine beta-lactamases.
PLoS Computational Biology
, 12
(6)
, Article e1004926. 10.1371/journal.pcbi.1004926.
|
Lees, JG;
Dawson, NL;
Sillitoe, I;
Orengo, CA;
(2016)
Functional innovation from changes in protein domains and their combinations.
Current Opinion in Structural Biology
, 38
pp. 44-52.
10.1016/j.sbi.2016.05.016.
|
Margineanu, A;
Chan, JJ;
Kelly, DJ;
Warren, SC;
Flatters, D;
Kumar, S;
Katan, M;
... French, PM; + view all
(2016)
Screening for protein-protein interactions using Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM).
Scientific Reports
, 6
, Article 28186. 10.1038/srep28186.
|
Martin, ACR;
Jayaram, N;
Usvyat, D;
(2016)
Evaluating tools for transcription factor binding site prediction.
BMC Bioinformatics
, 2016
, Article 1298. 10.1186/s12859-016-1298-9.
|
Martin, ACR;
Rees, AR;
(2016)
Extracting human antibody sequences from public databases for antibody humanization: high frequency of species assignment errors.
Protein Engineering Design and Selection
, 29
(10)
pp. 403-408.
10.1093/protein/gzw018.
|
Miyauchi, JT;
Chen, D;
Choi, M;
Nissen, JC;
Shroyer, KR;
Djordevic, S;
Zachary, IC;
... Tsirka, SE; + view all
(2016)
Ablation of neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression.
Oncotarget
, 7
(9)
pp. 9801-9814.
10.18632/oncotarget.6877.
|
Morgan, DJ;
Poolman, TM;
Williamson, AJK;
Wang, Z;
Clark, NR;
Ma'ayan, A;
Whetton, AD;
... Ray, DW; + view all
(2016)
Glucocorticoid receptor isoforms direct distinct mitochondrial programs to regulate ATP production.
Scientific Reports
, 6
, Article 26419. 10.1038/srep26419.
|
Mylona, A;
Theillet, F-X;
Foster, C;
Cheng, TM;
Miralles, F;
Bates, PA;
Selenko, P;
(2016)
Opposing effects of Elk-1 multisite phosphorylation shape its response to ERK activation.
Science
, 354
(6309)
pp. 233-237.
10.1126/science.aad1872.
|
Northey, T;
Venthur, H;
De Biasio, F;
Chauviac, F-X;
Cole, A;
Lisboa Ribeiro Junior, KA;
Grossi, G;
... Zhou, J-J; + view all
(2016)
Crystal Structures and Binding Dynamics of Odorant-Binding Protein 3 from two aphid species Megoura viciae and Nasonovia ribisnigri.
Scientific Reports
, 6
, Article 24739. 10.1038/srep24739.
|
Nowak, JS;
Hobor, F;
Downie Ruiz Velasco, A;
Choudhury, NR;
Heikel, G;
Kerr, A;
Ramos, A;
(2016)
Lin28a uses distinct mechanisms of binding to RNA and affects positively and negatively miRNA levels.
RNA
, 23
pp. 317-332.
10.1261/rna.059196.116.
|
Oberoi, J;
Dunn, DM;
Woodford, MR;
Mariotti, L;
Schulman, J;
Bourboulia, D;
Mollapour, M;
(2016)
Structural and functional basis of protein phosphatase 5 substrate specificity.
Proceedings of the National Academy of Sciences of the United States of America
, 113
(32)
pp. 9009-9014.
10.1073/pnas.1603059113.
|
Oliver, KV;
Marechal, A;
Rich, PR;
(2016)
Effects of the Hydration State on the Mid-Infrared Spectra of Urea and Creatinine in Relation to Urine Analyses.
Applied Spectroscopy
, 70
(6)
pp. 983-994.
10.1177/0003702816641263.
|
Oliver, KV;
Vilasi, A;
Maréchal, A;
Moochhala, SH;
Unwin, RJ;
Rich, PR;
(2016)
Infrared vibrational spectroscopy: a rapid and novel diagnostic and monitoring tool for cystinuria.
Scientific Reports
, 6
, Article 34737. 10.1038/srep34737.
|
Osborne, AJ;
Rodriguez de Cordoba, S;
Fremeaux-Bacchi, V;
Noris, M;
Smith, RJ;
van den Heuvel, B;
Goodship, THJ;
(2016)
Database of Complement Gene Variants: A comprehensive database providing insights on function, structure and allele frequency for genetic variants identified in complement-mediated diseases.
Immunobiology
, 221
(10)
, Article 206. 10.1016/j.imbio.2016.06.221.
|
Papaioannou, D;
Geibel, S;
Kunze, MB;
Kay, CW;
Waksman, G;
(2016)
Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide.
Protein Science
, 25
(3)
pp. 627-637.
10.1002/pro.2856.
|
Patani, H;
Bunney, TD;
Thiyagarajan, N;
Norman, RA;
Ogg, D;
Breed, J;
Ashford, P;
... Katan, M; + view all
(2016)
Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use.
Oncotarget
, 7
(17)
pp. 24252-24268.
10.18632/oncotarget.8132.
|
Penny, CJ;
Rahman, T;
Sula, A;
Miles, AJ;
Wallace, BA;
Patel, S;
(2016)
Isolated pores dissected from human two-pore channel 2 are functional.
Scientific Reports
, 6
, Article 38426. 10.1038/srep38426.
|
Perdios, L;
Bunney, TD;
Warren, SC;
Dunsby, C;
French, PM;
Tate, EW;
Katan, M;
(2016)
Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1.
Advances in Biological Regulation
, 60
pp. 6-13.
10.1016/j.jbior.2015.09.002.
|
Perkins, SJ;
Wright, DW;
Zhang, H;
Brookes, EH;
Chen, J;
Irving, TC;
Krueger, S;
... Curtis, JE; + view all
(2016)
Atomistic modelling of scattering data in the Collaborative Computational Project for Small Angle Scattering (CCP-SAS).
Journal of Applied Crystallography
, 49
(6)
pp. 1861-1875.
10.1107/S160057671601517X.
|
Phillips, IR;
Shephard, EA;
(2016)
Drug metabolism by flavin-containing monooxygenases of human and mouse.
Expert Opinion in Drug Metabolism and Toxicology
, 13
(2)
pp. 167-181.
10.1080/17425255.2017.1239718.
|
Proietti, G;
Abelak, KK;
Bishop-Bailey, D;
Macchiarulo, A;
Nobeli, I;
(2016)
Computational modelling of the binding of arachidonic acid to the human monooxygenase CYP2J2.
Journal of Molecular Modeling
, 22
(11)
, Article 279. 10.1007/s00894-016-3134-6.
|
Santos, AJ;
Durkin, CH;
Helaine, S;
Boucrot, E;
Holden, DW;
(2016)
Clustered Intracellular Salmonella enterica Serovar Typhimurium Blocks Host Cell Cytokinesis.
Infection and Immunity
, 84
(7)
pp. 2149-2158.
10.1128/IAI.00062-16.
|
Sheppard, C;
Blombach, F;
Belsom, A;
Schulz, S;
Daviter, T;
Smollett, K;
Mahieu, E;
... Werner, F; + view all
(2016)
Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP.
Nat Commun
, 7
, Article 13595. 10.1038/ncomms13595.
|
Sillitoe, I;
Furnham, N;
(2016)
FunTree: advances in a resource for exploring and contextualising protein function evolution.
Nucleic Acids Research
, 44
(D1)
D317-D323.
10.1093/nar/gkv1274.
|
Speranzini, V;
Rotili, D;
Ciossani, G;
Pilotto, S;
Marrocco, B;
Forgione, M;
Lucidi, A;
... Mattevi, A; + view all
(2016)
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.
Science Advances
, 2
(9)
, Article e1601017. 10.1126/sciadv.1601017.
|
Stubenrauch, C;
Belousoff, MJ;
Hay, ID;
Shen, H-H;
Lillington, J;
Tuck, KL;
Peters, KM;
... Lithgow, T; + view all
(2016)
Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine.
Nature Microbiology
, 1
, Article 16064. 10.1038/NMICROBIOL.2016.64.
|
Terry, C;
Wenborn, A;
Gros, N;
Sells, J;
Joiner, S;
Hosszu, LL;
Tattum, MH;
... Wadsworth, JD; + view all
(2016)
Ex vivo mammalian prions are formed of paired double helical prion protein fibrils.
Open Biology
, 6
(5)
10.1098/rsob.160035.
|
Tizei, PA;
Csibra, E;
Torres, L;
Pinheiro, VB;
(2016)
Selection platforms for directed evolution in synthetic biology.
Biochemical Society Transactions
, 44
(4)
pp. 1165-1175.
10.1042/BST20160076.
|
Torres, L;
Krüger, A;
Csibra, E;
Gianni, E;
Pinheiro, VB;
(2016)
Synthetic biology approaches to biological containment: pre-emptively tackling potential risks.
Essays in Biochemistry
, 60
(4)
pp. 393-410.
10.1042/EBC20160013.
|
Tsai, Y;
Fotinou, C;
Rana, R;
Yelland, T;
Frankel, P;
Zachary, I;
Djordjevic, S;
(2016)
Structural studies of neuropilin-2 reveal a zinc ion binding site away from the vascular endothelial growth factor binding pocket.
FEBS Journal
, 283
(10)
pp. 1921-1934.
10.1111/febs.13711.
|
Valleix, S;
Verona, G;
Jourde-Chiche, N;
Nédelec, B;
Mangione, PP;
Bridoux, F;
Mangé, A;
... Bellotti, V; + view all
(2016)
D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile.
Nature Communications
, 7
, Article 10353. 10.1038/ncomms10353.
|
Vemu, A;
Atherton, J;
Spector, JO;
Szyk, A;
Moores, CA;
Roll-Mecak, A;
(2016)
Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin.
Journal of Biological Chemistry
, 291
(25)
pp. 12907-12915.
10.1074/jbc.C116.731133.
|
Wannathong, T;
Waterhouse, JC;
Young, RE;
Economou, CK;
Purton, S;
(2016)
New tools for chloroplast genetic engineering allow the synthesis of human growth hormone in the green alga Chlamydomonas reinhardtii.
Applied Microbiology and Biotechnology
, 100
(12)
pp. 5467-5477.
10.1007/s00253-016-7354-6.
|
Watson, MD;
Peran, I;
Raleigh, DP;
(2016)
A Non-perturbing Probe of Coiled Coil Formation Based on Electron Transfer Mediated Fluorescence Quenching.
Biochemistry
, 55
(26)
pp. 3685-3691.
10.1021/acs.biochem.6b00270.
|
Waudby, CA;
Ramos, A;
Cabrita, LD;
Christodoulou, J;
(2016)
Two-Dimensional NMR Lineshape Analysis.
Scientific Reports
, 6
, Article 24826. 10.1038/srep24826.
|
Windwarder, M;
Yelland, T;
Djordjevic, S;
Altmann, F;
(2016)
Detailed characterization of the O-linked glycosylation of the neuropilin-1 c/MAM-domain.
Glycoconjugate Journal
, 33
(3)
pp. 387-397.
10.1007/s10719-015-9602-x.
|
Wu, S;
Majeed, SR;
Evans, TM;
Camus, MD;
Wong, NML;
Schollmeier, Y;
Park, M;
... Brodsky, FM; + view all
(2016)
Clathrin light chains' role in selective endocytosis influences antibody isotype switching.
PNAS - Proceedings of The National Academy of Sciences of The United States of America
, 113
(35)
pp. 9816-9821.
10.1073/pnas.1611189113.
|
Xu, Y;
Hellier, P;
Purton, S;
Baganz, F;
Ladommatos, N;
(2016)
Algal biomass and diesel emulsions: An alternative approach for utilizing the energy content of microalgal biomass in diesel engines.
Applied Energy
, 172
pp. 80-95.
10.1016/j.apenergy.2016.03.019.
|
Yachdav, G;
Wilzbach, S;
Rauscher, B;
Sheridan, R;
Sillitoe, I;
Procter, J;
Lewis, SE;
... Goldberg, T; + view all
(2016)
MSAViewer: interactive JavaScript visualization of multiple sequence alignments.
Bioinformatics
, 32
(22)
pp. 3501-3503.
10.1093/bioinformatics/btw474.
|
Yahara, K;
Furuta, Y;
Morimoto, S;
Kikutake, C;
Komukai, S;
Matelska, D;
Dunin-Horkawicz, S;
... Kobayashi, I; + view all
(2016)
Genome-wide survey of codons under diversifying selection in a highly recombining bacterial species, Helicobacter pylori.
DNA Research
, 23
(2)
pp. 135-143.
10.1093/dnares/dsw003.
|
Yelland, T;
Djordjevic, S;
(2016)
Crystal Structure of the Neuropilin-1 MAM Domain: Completing the Neuropilin-1 Ectodomain Picture.
Structure
, 24
(11)
pp. 2008-2015.
10.1016/j.str.2016.08.017.
|
Zahid, H;
Miah, L;
Lau, AM;
Brochard, L;
Hati, D;
Bui, TT;
Drake, AF;
... McDermott, LC; + view all
(2016)
Zinc-induced oligomerization of zinc α2 glycoprotein reveals multiple fatty acid-binding sites.
Biochemical Journal
, 473
(1)
pp. 43-54.
10.1042/BJ20150836.
|
Zeymer, C;
Werbeck, ND;
Zimmermann, S;
Reinstein, J;
Hansen, DF;
(2016)
Characterizing Active Site Conformational Heterogeneity along the Trajectory of an Enzymatic Phosphoryl Transfer Reaction.
Angewandte Chemie International Edition
, 55
(38)
pp. 11533-11537.
10.1002/anie.201606238.
|
Zeymer, C;
Werbeck, ND;
Zimmermann, S;
Reinstein, J;
Hansen, DF;
(2016)
Characterizing Active Site Conformational Heterogeneity along the Trajectory of an Enzymatic Phosphoryl Transfer Reaction.
Angewandte Chemie
, 128
(38)
pp. 11705-11709.
10.1002/ange.201606238.
|
Zhang, Y;
Kitazawa, S;
Peran, I;
Stenzoski, N;
McCallum, SA;
Raleigh, DP;
Royer, CA;
(2016)
High Pressure ZZ-Exchange NMR Reveals Key Features of Protein Folding Transition States.
Journal of the American Chemical Society
, 138
(46)
pp. 15260-15266.
10.1021/jacs.6b09887.
|
Zou, J;
Song, B;
Simmerling, C;
Raleigh, D;
(2016)
Experimental and Computational Analysis of Protein Stabilization by Gly-to-D-Ala Substitution: A Convolution of Native State and Unfolded State Effects.
Journal of the American Chemical Society
, 138
(48)
pp. 15682-15689.
10.1021/jacs.6b09511.
|
Book chapter
Henderson, B;
Fares, MA;
Martin, ACR;
(2016)
An introduction to the protein molecule.
In: Henderson, B and Fares, MA and Martin, ACR, (eds.)
Protein Moonlighting in Biology and Medicine.
(pp. 1-14).
John Wiley and Sons, Inc: London, UK.
|
Jeremy, G;
Stevens, J;
Lowe, AR;
(2016)
Single-Molecule Imaging to Characterize the Transport Mechanism of the Nuclear Pore Complex.
In:
Chromosome Architecture.
(pp. 17-35).
Springer: New York, NY, USA.
|
Martin, ACR;
(2016)
The structural basis of protein moonlighting.
In: Henderson, B and Fares, MA and Martin, ACR, (eds.)
Protein Moonlighting in Biology and Medicine.
(pp. 45-61).
John Wiley and Sons, Inc: London, UK.
|
Poster
Ferdous, S;
Martin, ACR;
(2016)
Exploration of conformational B-cell epitopes: components to peptide-based vaccines.
Presented at: 15th European Conference on Computational Biology (ECCB) 2016.
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Thesis
Das, S;
(2016)
Functional classification of protein domain superfamilies for protein function annotation.
Doctoral thesis , UCL (University College London).
|
Fung, KW;
(2016)
Molecular interactions of complement factor H and C4 using multidisciplinary biophysical methods.
Doctoral thesis , UCL (University College London).
|
Lizzul, AM;
(2016)
Integrated production of algal biomass.
Doctoral thesis , UCL (University College London).
|
Lockwood, NJ;
(2016)
The Global Imaging of Physiological and Pathophysiological Angiogenesis in live zebrafish using Optical Projection Tomography.
Doctoral thesis , UCL (University College London).
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