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Number of items: 41.

B

Balusu, Sriram; De Strooper, Bart; (2024) The necroptosis cell death pathway drives neurodegeneration in Alzheimer's disease. Acta Neuropathologica , 147 (1) , Article 96. 10.1007/s00401-024-02747-5. Green open access
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C

Clarke-Williams, Charlie J; Lopes-dos-Santos, Vítor; Lefèvre, Laura; Brizee, Demi; Causse, Adrien A; Rothaermel, Roman; Hartwich, Katja; ... Dupret, David; + view all (2024) Coordinating brain-distributed network activities in memory resistant to extinction. Cell , 187 (2) 409-427.e19. 10.1016/j.cell.2023.12.018. Green open access
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Crowley, Gerard; Attwell, David; Phatnani, Hemali; Sontheimer, Harald; Hong, Soyon; (2024) Glia in Neurodegenerative Disease. Cold Spring Harbor perspectives in biology a041375. 10.1101/cshperspect.a041375. (In press). Green open access
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D

de Boni, Laura; Wallis, Amber; Hays Watson, Aurelia; Ruiz-Riquelme, Alejandro; Leyland, Louise-Ann; Bourinaris, Thomas; Hannaway, Naomi; ... Bartels, Tim; + view all (2024) Aggregation-resistant alpha-synuclein tetramers are reduced in the blood of Parkinson's patients. EMBO Molecular Medicine 10.1038/s44321-024-00083-5. (In press). Green open access
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De Strooper, Bart; Haass, Christian; Hardy, John; Zetterberg, Henrik; (2024) Divisions over the regulation of lecanemab. The Lancet 10.1016/S0140-6736(24)02513-3. (In press).

De Strooper, Bart; Karran, Eric; (2024) New precision medicine avenues to the prevention of Alzheimer's disease from insights into the structure and function of γ-secretases. The EMBO Journal 10.1038/s44318-024-00057-w. (In press). Green open access
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Duggan, Michael R; Gomez, Gabriela T; Joynes, Cassandra M; Bilgel, Murat; Chen, Jingsha; Fattorelli, Nicola; Hohman, Timothy J; ... Walker, Keenan A; + view all (2024) Proteome-wide analysis identifies plasma immune regulators of amyloid-beta progression. Brain, Behavior, and Immunity , 120 pp. 604-619. 10.1016/j.bbi.2024.07.002. Green open access
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E

Erkert, Lena; Gamez-Belmonte, Reyes; Kabisch, Melanie; Schödel, Lena; Patankar, Jay V; Gonzalez-Acera, Miguel; Mahapatro, Mousumi; ... Becker, Christoph; + view all (2024) Alzheimer's disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis. Gut 10.1136/gutjnl-2023-331622. (In press). Green open access
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F

Farrell, Clíona; (2024) Exploring Alzheimer's disease and Down syndrome neuro-immune pathways using preclinical models and human post-mortem brain tissue. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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G

Germeys, Christine; Vandoorne, Tijs; Davie, Kristofer; Poovathingal, Suresh; Heeren, Kara; Vermeire, Wendy; Nami, FatemehArefeh; ... Van Den Bosch, Ludo; + view all (2024) Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response. Cell Reports , 43 (9) , Article 114719. 10.1016/j.celrep.2024.114719. Green open access
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Giamogante, Flavia; Barazzuol, Lucia; Maiorca, Francesca; Poggio, Elena; Esposito, Alessandra; Masato, Anna; Napolitano, Gennaro; ... Brini, Marisa; + view all (2024) A SPLICS reporter reveals -synuclein regulation of lysosome-mitochondria contacts which affects TFEB nuclear translocation. Nature Communications , 15 , Article 1516. 10.1038/s41467-024-46007-2. Green open access
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H

Hays Watson, Aurelia; (2024) The impact of lipid droplets on α-synuclein protein folding and aggregation propensities in Parkinson’s disease. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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I

Ibanez, Kristina; Jadhav, Bharati; Zanovello, Matteo; Gagliardi, Delia; Clarkson, Christopher; Facchini, Stefano; Garg, Paras; ... Tucci, Arianna; + view all (2024) Increased frequency of repeat expansion mutations across different populations. Nature Medicine 10.1038/s41591-024-03190-5. (In press). Green open access
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K

Kloske, CM; Mahinrad, S; Barnum, CJ; Batista, AF; Bradshaw, EM; Butts, B; Carrillo, MC; ... Wilcock, DM; + view all (2024) Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference. Alzheimer's & Dementia 10.1002/alz.14291. (In press). Green open access
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Koper, MJ; Moonen, S; Ronisz, A; Ospitalieri, S; Callaerts-Vegh, Z; T'Syen, D; Rabe, S; ... Thal, DR; + view all (2024) Inhibition of an Alzheimer’s disease–associated form of necroptosis rescues neuronal death in mouse models. Science Translational Medicine , 16 (771) , Article eadf5128. 10.1126/scitranslmed.adf5128. Green open access
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L

Lam, Isabel; Ndayisaba, Alain; Lewis, Amanda J; Fu, YuHong; Sagredo, Giselle T; Kuzkina, Anastasia; Zaccagnini, Ludovica; ... Khurana, Vikram; + view all (2024) Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions. Neuron 10.1016/j.neuron.2024.06.002. (In press). Green open access
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Lloyd, AF; Martinez-Muriana, A; Davis, E; Daniels, MJD; Hou, P; Mancuso, R; Brenes, AJ; ... Howden, AJM; + view all (2024) Deep proteomic analysis of microglia reveals fundamental biological differences between model systems. Cell Reports , 43 (11) , Article 114908. 10.1016/j.celrep.2024.114908. Green open access
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M

Mallach, A; Zielonka, M; van Lieshout, V; An, Y; Khoo, JH; Vanheusden, M; Chen, WT; ... De Strooper, B; + view all (2024) Microglia-astrocyte crosstalk in the amyloid plaque niche of an Alzheimer's disease mouse model, as revealed by spatial transcriptomics. Cell Reports , 43 (6) , Article 114216. 10.1016/j.celrep.2024.114216. Green open access
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Mancuso, R; Fattorelli, N; Martinez-Muriana, A; Davis, E; Wolfs, L; Van Den Daele, J; Geric, I; ... De Strooper, B; + view all (2024) Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology. Nature Neuroscience 10.1038/s41593-024-01600-y. (In press). Green open access
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Masato, Anna; Andolfo, Annapaola; Favetta, Giulia; Bellini, Edoardo Niccolo; Cogo, Susanna; Dalla Valle, Luisa; Boassa, Daniela; ... Bubacco, Luigi; + view all (2024) Sequestosome-1 (SQSTM1/p62) as a target in dopamine catabolite-mediated cellular dyshomeostasis. Cell Death & Disease , 15 , Article 424. 10.1038/s41419-024-06763-x. Green open access
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Masato, Anna; Bubacco, Luigi; (2024) The αSynuclein half-life conundrum. Neurobiology of Disease , 196 , Article 106524. 10.1016/j.nbd.2024.106524. Green open access
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Masato, Anna; Panzi, Chiara; Butnaru, Ioana; Restani, Laura; Mazzo, Francesca; Sher, Emanuele; Bose, Suchira; (2024) Synaptic Release of Pathological Tau Is Calcium- and SNAP25-Dependent, and Blocked by BoNT-A Activity. Toxicon , 237 (Supp 1) , Article 107450. 10.1016/j.toxicon.2024.107450. Green open access
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Milioto, Carmelo; Carcolé, Mireia; Giblin, Ashling; Coneys, Rachel; Attrebi, Olivia; Ahmed, Mhoriam; Harris, Samuel S; ... Isaacs, Adrian M; + view all (2024) PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons. Nature Neuroscience 10.1038/s41593-024-01589-4. (In press). Green open access
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Mumford, Paige Soleil; (2024) Preclinical modelling of altered neuroinflammation and interferon hyper-sensitivity in Alzheimer’s disease-Down syndrome. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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N

Nazish, Iqra; Mamais, Adamantios; Mallach, Anna; Bettencourt, Conceisao; Kaganovich, Alice; Warner, Thomas; Hardy, John; ... Bandopadhyay, Rina; + view all (2024) Differential LRRK2 signalling and gene expression in WT-LRRK2 and G2019S-LRRK2 mouse microglia treated with zymosan and MLi2. Cells , 13 (1) , Article 53. 10.3390/cells13010053. Green open access
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O

Obensa Bertroli, Clara; (2024) Glucocerebrosidase dysfunction results in increased membrane binding and aggregation propensity of α-synuclein in Parkinson's disease. Doctoral thesis (Ph.D), UCL (University College London).

P

Pappolla, Miguel A; Refolo, Lorenzo; Sambamurti, Kumar; Zambon, Daniel; Duff, Karen; (2024) Hypercholesterolemia and Alzheimer’s Disease: Unraveling the Connection and Assessing the Efficacy of Lipid-Lowering Therapies. Journal of Alzheimer's Disease , 101 (s1) S371-S393. 10.3233/JAD-240388. Green open access
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Preman, Pranav; Moechars, Daan; Fertan, Emre; Wolfs, Leen; Serneels, Lutgarde; Shah, Disha; Lamote, Jochen; ... De Strooper, Bart; + view all (2024) APOE from astrocytes restores Alzheimer's Aβ-pathology and DAM-like responses in APOE deficient microglia. EMBO Molecular Medicine 10.1038/s44321-024-00162-7. (In press). Green open access
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Prosser, Lloyd; (2024) Investigating Imaging Biomarkers in Normal Ageing and Cognitive Impairment. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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R

Rajani, Rikesh M; Ellingford, Robert; Hellmuth, Mariam; Harris, Samuel S; Taso, Orjona S; Graykowski, David; Lam, Francesca Kar Wey; ... Busche, Marc Aurel; + view all (2024) Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's disease. PLoS Biology , 22 (7) , Article ARTN e3002727. 10.1371/journal.pbio.3002727. Green open access
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S

Schmidt, Andree; Hrupka, Brian; van Bebber, Frauke; Sunil Kumar, Sanjay; Feng, Xiao; Tschirner, Sarah K; Aßfalg, Marlene; ... Lichtenthaler, Stefan F; + view all (2024) The Alzheimer's disease-linked protease BACE2 cleaves VEGFR3 and modulates its signaling. The Journal of Clinical Investigation , Article e170550. 10.1172/JCI170550. (In press). Green open access
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Scott-Solache, James; (2024) TREM2 signaling regulates microglial homeostatic functions. Doctoral thesis (Ph.D), UCL (University College London.

Serneels, L; Bammens, L; Zwijsen, A; Tolia, A; Chávez-Gutiérrez, L; De Strooper, B; (2024) Functional and topological analysis of PSENEN, the fourth subunit of the γ-secretase complex. Journal of Biological Chemistry , 300 (1) , Article 105533. 10.1016/j.jbc.2023.105533. Green open access
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Simmonds, Emily; Leonenko, Ganna; Yaman, Umran; Bellou, Eftychia; Myers, Amanda; Morgan, Kevin; Brookes, Keeley; ... Escott-Price, Valentina; + view all (2024) Chromosome X-wide association study in case control studies of pathologically confirmed Alzheimer's disease in a European population. Translational Psychiatry , 14 , Article 358. 10.1038/s41398-024-03058-9. Green open access
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Sokolova, Dimitra; Ghansah, Shari Addington; Puletti, Francesca; Georgiades, Tatiana; De Schepper, Sebastiaan; Zheng, Yongjing; Crowley, Gerard; ... Hong, Soyon; + view all (2024) Astrocyte-derived MFG-E8 facilitates microglial synapse elimination in Alzheimer's disease mouse models. BioRXiv: Cold Spring Harbor, NY, USA. Green open access
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T

Taddei, Raquel N; (2024) Understanding the role of glia and oligomeric tau in the early synapse loss of Alzheimer disease dementia. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Thal, Dietmar Rudolf; De Strooper, Bart; (2024) Regulated cell death in neurodegeneration: pathways and therapeutic horizons. Acta Neuropathologica , 148 , Article 47. 10.1007/s00401-024-02808-9.

V

Vandermeulen, Lina; Geric, Ivana; Fumagalli, Laura; Kreir, Mohamed; Lu, Ashley; Nonneman, Annelies; Premereur, Jessie; ... Mancuso, Renzo; + view all (2024) Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease. , Article 37. 10.1186/s13024-024-00725-9. Green open access
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W

Watamura, Naoto; Foiani, Martha S; Bez, Sumi; Bourdenx, Mathieu; Santambrogio, Alessia; Frodsham, Claire; Camporesi, Elena; ... Saido, Takaomi C; + view all (2024) In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds. Nature Neuroscience , 28 pp. 293-307. 10.1038/s41593-024-01829-7. Green open access
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Z

Zelek, Wioleta M; Bevan, Ryan J; Nimmo, Jacqui; Dewilde, Maarten; De Strooper, Bart; Morgan, B Paul; (2024) Brain-penetrant complement inhibition mitigates neurodegeneration in an Alzheimer's disease mouse model. Brain 10.1093/brain/awae278. (In press). Green open access
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Zilio, Gianluca; Masato, Anna; Sandre, Michelle; Caregnato, Alberto; Moret, Francesca; Maciola, Agnieszka Katarzyna; Antonini, Angelo; ... Bubacco, Luigi; + view all (2024) SARS-CoV-2-Mimicking Pseudoviral Particles Accelerate α-Synuclein Aggregation In Vitro. ACS Chemical Neuroscience , 15 (2) pp. 215-221. 10.1021/acschemneuro.3c00468. Green open access
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This list was generated on Mon Feb 17 01:44:06 2025 GMT.