Browse by UCL Departments and Centres
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Number of items: 110.
A
Ahn, Jehyun;
Lee, Eun Hye;
Yoo, Heejin;
Shin, Daeun;
Kang, Heekyoung;
Yim, Sohyun;
Kim, Seongmi;
... K-ROAD study group; + view all
(2025)
Tailoring thresholds for interpreting plasma p-tau217 levels.
Journal of Neurology, Neurosurgery and Psychiatry
10.1136/jnnp-2025-335830.
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Akeret, K;
Padevit, L;
Reifenberger, G;
Von Deimling, A;
Weller, M;
Le Rhun, E;
Bink, A;
... Sahm, F; + view all
(2025)
Anatomic Staging of H3 G34-Mutant Diffuse Hemispheric Glioma.
Neurology
, 105
(3)
, Article e213861. 10.1212/WNL.0000000000213861.
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Ao, Jiarui;
Picard, Cynthia;
Auld, Daniel;
Zetterberg, Henrik;
Brinkmalm, Ann;
Blennow, Kaj;
Villeneuve, Sylvia;
... PREVENT-AD research group; + view all
(2025)
Novel synaptic markers predict early tau pathology and cognitive deficit in an asymptomatic population at risk of Alzheimer’s disease.
Molecular Psychiatry
, 30
pp. 2810-2820.
10.1038/s41380-024-02884-z.
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B
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Balendra, R;
Sreedharan, J;
Hallegger, M;
Luisier, R;
Lashuel, HA;
Gregory, JM;
Patani, R;
(2025)
Amyotrophic lateral sclerosis caused by TARDBP mutations: from genetics to TDP-43 proteinopathy.
The Lancet Neurology
, 24
(5)
pp. 456-470.
10.1016/S1474-4422(25)00109-7.
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Bateman, RJ;
Li, Y;
McDade, EM;
Llibre-Guerra, JJ;
Clifford, DB;
Atri, A;
Mills, SL;
... Schofield, PR; + view all
(2025)
Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial.
The Lancet Neurology
, 24
(4)
pp. 316-330.
10.1016/S1474-4422(25)00024-9.
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Belder, Christopher RS;
Boche, Delphine;
Nicoll, James AR;
Jaunmuktane, Zane;
Zetterberg, Henrik;
Schott, Jonathan M;
Barkhof, Frederik;
(2025)
Amyloid-related iatrogenic atrophy of the brain: data transparency is an urgent safety priority – Authors' reply.
The Lancet Neurology
, 24
(3)
p. 190.
10.1016/S1474-4422(25)00030-4.
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Bhome, Rohan;
Thomas, George EC;
Hannaway, Naomi;
Dobreva, Ivelina;
Zarkali, Angeliki;
Shmueli, Karin;
Cole, James H;
(2025)
Quantitative susceptibility mapping reveals differences between subtypes of Lewy body dementia.
Brain
, Article awaf325. 10.1093/brain/awaf325.
(In press).
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Boyanova, Sevda;
Banks, Gareth;
Lipina, Tatiana V;
Bains, Rasneer Sonia;
Forrest, Hamish;
Stewart, Michelle;
Carcolé, Mireia;
... Wiseman, Frances K; + view all
(2025)
Multi-modal comparative phenotyping of knock-in mouse models of frontotemporal dementia/amyotrophic lateral sclerosis.
Disease Models & Mechanisms
, 18
(8)
, Article dmm052324. 10.1242/dmm.052324.
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Brown, Thomas M;
James, Sarah-Naomi;
Nicholas, Jennifer M;
Keuss, Sarah;
Keshavan, Ashvini;
Malone, Ian B;
Coath, William;
... Barnes, Josephine; + view all
(2025)
Association of Increase in White Matter Hyperintensity Volume With Rate of Hippocampal Atrophy in a Population-Based Study of Aging.
Neurology
, 105
(5)
, Article e213975. 10.1212/WNL.0000000000213975.
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Bunting, Emma L;
Donaldson, Jasmine;
Cumming, Sarah A;
Olive, Jessica;
Broom, Elizabeth;
Miclaus, Mihai;
Hamilton, Joseph;
... Tabrizi, Sarah J; + view all
(2025)
Antisense oligonucleotide–mediated MSH3 suppression reduces somatic CAG repeat expansion in Huntington's disease iPSC–derived striatal neurons.
Science Translational Medicine
, 17
(785)
, Article eadn4600. 10.1126/scitranslmed.adn4600.
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C
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Cacciaglia, R;
Falcón, C;
Benavides, GS;
Brugulat-Serrat, A;
Alomà, MM;
Calvet, MS;
Molinuevo, JL;
... The ALFA study; + view all
(2025)
Soluble Aβ pathology predicts neurodegeneration and cognitive decline independently on p-tau in the earliest Alzheimer's continuum: Evidence across two independent cohorts.
Alzheimer's and Dementia
, Article e14415. 10.1002/alz.14415.
(In press).
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Calame, DG;
Wong, JH;
Panda, P;
Nguyen, DT;
Leong, NCP;
Sangermano, R;
Patankar, SG;
... Nguyen, LN; + view all
(2025)
Biallelic variation in the choline and ethanolamine transporter FLVCR1 underlies a severe developmental disorder spectrum.
Genetics in Medicine
, 27
(1)
, Article 101273. 10.1016/j.gim.2024.101273.
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Carrol, D;
Busse, WW;
Frye, CJ;
Klaus, DR;
Bach, JC;
Floerke, H;
Bendlin, BB;
... Rosenkranz, MA; + view all
(2025)
Regional brain structural alterations in reward and salience networks in asthma.
Brain, Behavior, and Immunity
, 126
pp. 80-97.
10.1016/j.bbi.2025.01.028.
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Coleman, Annabelle;
Touzé, Alexiane;
Farag, Mena;
Pengo, Marta;
Murphy, Michael J;
Hassan, Yara;
Thackeray, Olivia;
... Byrne, Lauren M; + view all
(2025)
Evaluating finger-prick blood collection for remote quantification of neurofilament light in neurological diseases.
Journal of Neurology
, 272
(8)
, Article 501. 10.1007/s00415-025-13232-8.
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Cummings, Jeffrey L;
Teunissen, Charlotte E;
Fiske, Brian K;
Le Ber, Isabelle;
Wildsmith, Kristin R;
Schoell, Michael;
Dunn, Billy;
(2025)
Biomarker-guided decision making in clinical drug development for neurodegenerative disorders.
Nature Reviews Drug Discovery
, 24
pp. 589-609.
10.1038/s41573-025-01165-w.
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D
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De Boer, Liset;
Jiskoot, Lize C;
Seelaar, Harro;
Van Swieten, John C;
Ibanez, Agustin;
Maito, Marcelo;
Fittipaldi, Sol;
... the GENFI, Consortium; + view all
(2025)
Cross-country variance in facial emotion recognition in presymptomatic and symptomatic behavioral variant frontotemporal dementia: Insights from the GENFI and ReDLat consortia.
Alzheimer's & Dementia
, 21
(10)
, Article e70741. 10.1002/alz.70741.
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De Bruin, Hannah;
Groot, Colin;
Barthel, Henryk;
Bischof, Gérard N;
Blazhenets, Ganna;
Boellaard, Ronald;
Boon, Baayla DC;
... Ossenkoppele, Rik; + view all
(2025)
Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease.
Brain
, Article awaf279. 10.1093/brain/awaf279.
(In press).
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De Houwer, Julie FH;
Dopper, Elise G;
Van Buuren, Renee;
Stokkel, Marijke;
De Boer, Liset;
Swartenbroekx, Tine;
Boesjes, Pam A;
... Seelaar, Harro; + view all
(2025)
Distinct proteomic CSF profiles in genetic frontotemporal lobar degeneration.
Brain
, Article awaf457. 10.1093/brain/awaf457.
(In press).
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De Strooper, Bart;
Haass, Christian;
Hardy, John;
Zetterberg, Henrik;
(2025)
The regulatory rollercoaster continues—EMA refuses donanemab.
The Lancet
, 405
(10492)
pp. 1810-1812.
10.1016/S0140-6736(25)00833-5.
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Delvenne, Aurore;
Gobom, Johan;
Reus, Lianne M;
Dobricic, Valerija;
Ten Kate, Mara;
Schindler, Suzanne E;
Ramakers, Inez;
... Vos, Stephanie JB; + view all
(2025)
Cerebrospinal fluid proteomic profiling of cognitively unimpaired individuals with suspected non-Alzheimer's disease pathophysiology.
Brain Communications
, 7
(4)
, Article fcaf253. 10.1093/braincomms/fcaf253.
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Dijsselhof, Mathijs BJ;
Moore, Candace;
Amiri, Saba;
Tee, Mervin;
Hilal, Saima;
Chen, Christopher;
van den Born, Bert-Jan H;
... Petr, Jan; + view all
(2025)
Multi-cohort, multi-sequence harmonisation for cerebrovascular brain age.
Imaging Neurosci (Camb)
, 3
, Article IMAG.a.964. 10.1162/IMAG.a.964.
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Donaldson, Jasmine;
Hensman Moss, Davina;
Ciosi, Marc;
Usdin, Karen;
Balmus, Gabriel;
Monckton, Darren G;
Tabrizi, Sarah J;
(2025)
Huntington disease: somatic expansion, pathobiology and therapeutics.
Nature Reviews Neurology
10.1038/s41582-025-01159-7.
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Doniza, Liad;
Lee, Mitchel;
Blumenfeld-Katzir, Tamar;
Artzi, Moran;
Ben-Bashat, Dafna;
Aizenstein, Orna;
Radunsky, Dvir;
... Ben-Eliezer, Noam; + view all
(2025)
Noise propagation and MP-PCA image denoising for high-resolution quantitative R₂*, T₂*, and magnetic susceptibility mapping (QSM).
IEEE Transactions on Biomedical Engineering
10.1109/TBME.2025.3566561.
(In press).
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Durmishi, Xhuljana;
(2025)
Investigating the role of Hepacam in Müller Glial morphogenesis in the zebrafish retina.
Doctoral thesis (Ph.D), UCL (University College London).
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E
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El-Dessouky, Sara H;
Sharaf-Eldin, Wessam E;
Aboulghar, Mona M;
Mousa, Hatem A;
Zaki, Maha S;
Maroofian, Reza;
Senousy, Sameh M;
... Abdalla, Ebtesam M; + view all
(2025)
Integrating Prenatal Exome Sequencing and Ultrasonographic Fetal Phenotyping for Assessment of Congenital Malformations: High Molecular Diagnostic Yield and Novel Phenotypic Expansions in a Consanguineous Cohort.
Clinical Genetics
10.1111/cge.14712.
(In press).
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Eratne, Dhamidhu;
Li, Qiao-Xin;
Lewis, Courtney;
Dang, Christa;
Kang, Matthew JY;
Grewal, Jasleen;
Loi, Samantha;
... MiND Study Group; + view all
(2025)
Strong diagnostic performance of plasma ptau217 for CSF biomarker-defined young-onset Alzheimer disease in a diagnostically heterogeneous clinical cohort.
Journal of Neurology
, 272
, Article 25. 10.1007/s00415-024-12732-3.
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Estevez-Fraga, Carlos;
Sebenius, Isaac;
Hansen, Justine Y;
Haenisch, Benjamin;
Zeun, Paul;
Scahill, Rachael I;
Gregory, Sarah;
... McColgan, Peter; + view all
(2025)
Cell-specific mechanisms drive connectivity across the time course of Huntington’s disease.
Nature Communications
, 16
, Article 5519. 10.1038/s41467-025-60556-0.
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F
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Farag, M;
Knights, H;
Scahill, RI;
McColgan, P;
Estevez-Fraga, C;
(2025)
Neuroimaging Techniques in Huntington's Disease: A Critical Review.
Movement Disorders Clinical Practice
10.1002/mdc3.70010.
(In press).
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Farag, Mena;
Murphy, Michael J;
Hobbs, Nicola Z;
Leocadi, Michela;
Fayer, Kate;
Thackeray, Olivia;
Gobom, Johan;
... Scahill, Rachael I; + view all
(2025)
Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease.
Movement Disorders
10.1002/mds.70062.
(In press).
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Farag, Mena;
Tabrizi, Sarah J;
Wild, Edward J;
(2025)
Huntington's disease clinical trials update: October 2025.
Journal of Huntington's Disease
10.1177/18796397251399751.
(In press).
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Farrell, C;
Buhidma, Y;
Mumford, P;
Heywood, WE;
Hällqvist, J;
Flores-Aguilar, L;
Andrews, EJ;
... Wiseman, FK; + view all
(2025)
Apolipoprotein E abundance is elevated in the brains of individuals with Down syndrome-Alzheimer's disease.
Acta Neuropathologica
, 149
(1)
, Article 49. 10.1007/s00401-025-02889-0.
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Fodder, Katherine Elizabeth;
(2025)
The role of DNA methylation and oligodendrocytes in neurodegeneration.
Doctoral thesis (Ph.D), UCL (University College London).
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Foley, A Reghan;
Bolduc, Véronique;
Guirguis, Fady;
Donkervoort, Sandra;
Hu, Ying;
Orbach, Rotem;
McCarty, Riley M;
... Bönnemann, Carsten G; + view all
(2025)
Characterization of severe COL6-related dystrophy due to the recurrent variant COL6A1 c.930+189C>T.
Brain
10.1093/brain/awaf116.
(In press).
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Fox, Nick C;
Belder, Christopher;
Ballard, Clive;
Kales, Helen C;
Mummery, Catherine;
Caramelli, Paulo;
Ciccarelli, Olga;
... Frisoni, Giovanni B; + view all
(2025)
Treatment for Alzheimer's disease.
The Lancet
, 406
(10510)
pp. 1408-1423.
10.1016/S0140-6736(25)01329-7.
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Frisoni, Giovanni B;
Aho, Emil;
Brayne, Carol;
Ciccarelli, Olga;
Dubois, Bruno;
Fox, Nick C;
Frederiksen, Kristian S;
... Hansson, Oskar; + view all
(2025)
Alzheimer's disease outlook: controversies and future directions.
The Lancet
, 406
(10510)
pp. 1424-1442.
10.1016/S0140-6736(25)01389-3.
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G
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Giblin, Ashling;
Cammack, Alexander J;
Blomberg, Niek;
Anoar, Sharifah;
Mikheenko, Alla;
Carcole, Mireia;
Atilano, Magda L;
... Isaacs, Adrian M; + view all
(2025)
Neuronal polyunsaturated fatty acids are protective in ALS/FTD.
Nature Neuroscience
, 28
(4)
pp. 737-747.
10.1038/s41593-025-01889-3.
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Giblin, Ashling;
Cammack, Alexander J;
Blomberg, Niek;
Anoar, Sharifah;
Mikheenko, Alla;
Carcole, Mireia;
Atilano, Magda L;
... Isaacs, Adrian M; + view all
(2025)
Neuronal polyunsaturated fatty acids are protective in ALS/FTD (Feb, 10.1038/s41593-025-01889-3, 2025).
[Corrigendum].
Nature Neuroscience
, 28
(4)
p. 913.
10.1038/s41593-025-01926-1.
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Gogniat, Marissa A;
Khan, Omair A;
Ratangee, Brina;
Bolton, Corey J;
Zhang, Panpan;
Liu, Dandan;
Pechman, Kimberly R;
... Jefferson, Angela L; + view all
(2025)
Cross-Sectional and Longitudinal Associations of Neighborhood Disadvantage With Fluid Biomarkers of Neuroinflammation and Neurodegeneration.
Neurology
, 105
(2)
, Article e213770. 10.1212/WNL.0000000000213770.
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Groves, J;
Mallon, DH;
Borg, A;
Zaidman, N;
Foltynie, T;
Limousin, P;
Mehta, AR;
(2025)
Myelopathic motor symptoms overlaying Parkinson's disease.
Practical Neurology
10.1136/pn-2025-004546.
(In press).
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H
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Hannaway, Naomi;
Zarkali, Angeliki;
Bhome, Rohan;
Dobreva, Ivelina;
Thomas, George Ec;
Veleva, Elena;
Belio, Irene Gorostiaga;
... Weil, Rimona S; + view all
(2025)
Reply: Reconsidering white matter vulnerability and biomarker interpretation across Lewy body dementia subtypes.
Alzheimers Dement
, 21
(8)
, Article e70567. 10.1002/alz.70567.
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Heneka, Michael T;
Van der Flier, Wiesje M;
Jessen, Frank;
Hoozemanns, Jeroen;
Thal, Dietmar Rudolf;
Boche, Delphine;
Brosseron, Frederic;
... Riechers, Sean-Patrick; + view all
(2025)
Neuroinflammation in Alzheimer disease.
Nature Reviews Immunology
, 25
pp. 321-352.
10.1038/s41577-024-01104-7.
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Hewlett, Bailey;
(2025)
Determining the Essential Roles of IRE1 Membrane Stress Responses upon Disruptions in Inter-Organelle Contacts.
Doctoral thesis (Ph.D), UCL (University College London).
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Hölbling, BV;
Gupta, Y;
Marchi, PM;
Atilano, ML;
Flower, M;
Ureña, E;
Goulden, RA;
... Isaacs, AM; + view all
(2025)
A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons.
Cell Reports
, 44
(5)
, Article 115695. 10.1016/j.celrep.2025.115695.
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J
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Jakabek, D;
Isaacs, AM;
De Strooper, B;
Tuszynski, M;
Lane, R;
Uspenskaya, O;
McDade, E;
... Mummery, CJ; + view all
(2025)
CTAD taskforce: genetic therapies in Alzheimer’s disease.
The Journal of Prevention of Alzheimer's Disease
, Article 100269. 10.1016/j.tjpad.2025.100269.
(In press).
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John, Amber;
Desai, Roopal;
Eshetu, Aphrodite;
Willroth, Emily;
Marchant, Natalie;
Woodward-Carlton, Barbara;
Cadar, Dorina;
... Stott, Joshua; + view all
(2025)
Wellbeing and memory function: testing bidirectional associations in the English Longitudinal Study of Ageing (ELSA).
Aging & Mental Health
, 29
(10)
pp. 1807-1813.
10.1080/13607863.2025.2468408.
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K
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Kempthorne, Liam;
Vaizoglu, Deniz;
Cammack, Alexander J;
Carcolé, Mireia;
Roberts, Martha J;
Mikheenko, Alla;
Fisher, Alessia;
... Isaacs, Adrian M; + view all
(2025)
Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo.
Nature Communications
, 16
, Article 459. 10.1038/s41467-024-55550-x.
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Khetarpal, Vinod;
Herbst, Todd;
Dominguez, Celia;
Munoz-Sanjuan, Ignacio;
Sampaio, Cristina;
Marks, Bryan;
Miller, Dennis L;
... Pacifici, Robert; + view all
(2025)
Lack of evidence for kynurenine pathway dysfunction in Huntington's disease: Cerebrospinal fluid and plasma analyses from the HDClarity study.
Journal of Huntington's Disease
10.1177/18796397241301761.
(In press).
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Kim, SYH;
Jeon, YH;
Rossor, M;
(2025)
Dementia Intervention Trials and Opportunity Costs for Potential Participants.
Alzheimer Disease and Associated Disorders
, 39
(4)
pp. 313-314.
10.1097/WAD.0000000000000685.
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Knights, Harry;
Coleman, Annabelle;
Farag, Mena;
Leocadi, Michela;
Murphy, Michael;
Fayer, Kate;
Thackeray, Olivia;
... HD-YAS investigators; + view all
(2025)
Bias in HD-ISS staging introduced by the FreeSurfer cross-sectional stream: Insights from the Huntington's Disease Young Adult Study (HD-YAS).
Journal of Huntington's Disease
10.1177/18796397251366900.
(In press).
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Knorr, Ulla;
Simonsen, Anja Hviid;
Nilsson, Johanna;
Brinkmalm, Ann;
Zetterberg, Henrik;
Blennow, Kaj;
Knudsen, Mark Bech;
... Kessing, Lars Vedel; + view all
(2025)
Associations between cerebrospinal fluid synaptic protein biomarkers and cognitive function in bipolar disorder.
Journal of Psychiatric Research
, 184
pp. 288-296.
10.1016/j.jpsychires.2025.03.005.
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Kodosaki, E;
Zetterberg, H;
Heslegrave, A;
(2025)
Current Methods in Clinical Alzheimer’s Disease Research and Diagnosis.
Molecular Diagnosis and Therapy
10.1007/s40291-025-00789-3.
(In press).
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Körtvelyessy, P;
Arslan, B;
Nietiet, J;
Leithner, C;
Hühnchen, P;
Böhmerle, W;
Endres, M;
... Göschel, L; + view all
(2025)
The expanding clinical utility of blood neurofilament light chain (bNfL): a multi-disciplinary diagnostic tool.
Journal of the Neurological Sciences
, 478
, Article 123669. 10.1016/j.jns.2025.123669.
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L
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Labonte, Jacob;
Sugarman, Michael A;
Pettway, Erika;
Zetterberg, Henrik;
Blennow, Kaj;
Ashton, Nicholas J;
Karikari, Thomas K;
... Alosco, Michael L; + view all
(2025)
Sex differences on tau, astrocytic, and neurodegenerative plasma biomarkers.
Journal of Alzheimer's Disease
, 105
(2)
pp. 443-452.
10.1177/13872877251329468.
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Leuzy, Antoine;
Bollack, Ariane;
Pellegrino, Daniela;
Teunissen, Charlotte E;
La Joie, Renaud;
Rabinovici, Gil D;
Franzmeier, Nicolai;
... Farrar, Gill; + view all
(2025)
Considerations in the clinical use of amyloid PET and CSF biomarkers for Alzheimer's disease.
Alzheimer's & Dementia
, 21
(3)
, Article e14528. 10.1002/alz.14528.
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Liu, Ella;
Jones, Sherri Lee;
Light, Victoria;
Teunissen, Charlotte;
Bouzigues, Arabella;
Russell, Lucy L;
Foster, Phoebe H;
... Ducharme, Simon; + view all
(2025)
Accuracy of blood-based neurofilament light to different genetic frontotemporal dementia from primary psychiatric disorders.
Journal of Alzheimer’s Disease
, 106
(4)
pp. 1337-1354.
10.1177/13872877251352103.
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Llibre-Guerra, JJ;
Fernandez, MV;
Joseph-Mathurin, N;
Bian, S;
Carter, K;
Li, Y;
Aschenbrenner, AJ;
... Ikeuchi, T; + view all
(2025)
Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia.
Nature Medicine
, 31
(4)
pp. 1267-1275.
10.1038/s41591-025-03494-0.
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Lousley, Chiara;
Stott, Joshua;
Fearn, Caroline;
El Baou, Céline;
Kurana, Suman;
Brotherhood, Emilie V;
Spector, Aimee;
(2025)
Cognitive stimulation in non-memory led dementias: A scoping review.
Dementia
10.1177/14713012251342018.
(In press).
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Ly, Monica T;
Altaras, Caroline;
Tripodis, Yorghos;
Adler, Charles H;
Balcer, Laura J;
Bernick, Charles;
Zetterberg, Henrik;
... Alosco, Michael L; + view all
(2025)
Single- versus two-test criteria for cognitive impairment: associations with CSF and imaging markers in former American football players.
The Clinical Neuropsychologist
10.1080/13854046.2025.2451828.
(In press).
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M
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Machado, Luiza S;
Vidor, Pedro;
Perquim, Lavínia;
Limberger, Christian;
Machado, Leonardo;
Rocha, Andréia;
Soares, Carolina;
... Zimmer, Eduardo R; + view all
(2025)
Association between FDG- and TSPO-PET signals across human and animal studies investigating neurodegenerative conditions: a systematic review.
Molecular Psychiatry
10.1038/s41380-025-03160-4.
(In press).
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Masebo, Lehane;
Whitfield, Tim;
Demnitz-King, Harriet;
Heslegrave, Amanda;
Poisnel, Geraldine;
Lutz, Antoine;
Frison, Eric;
... Marchant, Natalie L; + view all
(2025)
Can non-pharmacological interventions change levels of neurofilament light in older adults at risk of dementia? A secondary analysis of the SCD-Well randomized clinical trial.
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