Browse by UCL people
Group by: Type | Date
Number of items: 40.
Article
Bailey, C;
Bourne, RM;
Siow, B;
Johnston, EW;
Brizmohun Appayya, M;
Pye, H;
Heavey, S;
... Panagiotaki, E; + view all
(2019)
VERDICT MRI validation in fresh and fixed prostate specimens using patient-specific moulds for histological and MR alignment.
NMR in Biomedicine
, Article e4073. 10.1002/nbm.4073.
(In press).
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Bakkalci, Deniz;
Al-Badri, Georgina;
Yang, Wei;
Nam, Andy;
Liang, Yan;
Khurram, Syed Ali;
Heavey, Susan;
... Cheema, Umber; + view all
(2024)
Spatial transcriptomic interrogation of the tumour-stroma boundary in a 3D engineered model of ameloblastoma.
Materials Today Bio
, 24
, Article 100923. 10.1016/j.mtbio.2023.100923.
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Barma, N;
Stone, TC;
Carmona Echeverria, LM;
Heavey, S;
(2021)
Exploring the Value of BRD9 as a Biomarker, Therapeutic Target and Co-Target in Prostate Cancer.
Biomolecules
, 11
(12)
, Article 1794. 10.3390/biom11121794.
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Bourne, RM;
Bailey, CEM;
Johnston, EW;
Pye, H;
Heavey, S;
Whitaker, H;
Siow, B;
... Panagiotaki, E; + view all
(2017)
Apparatus for histological validation of in vivo and ex vivo magnetic resonance imaging of the human prostate.
Frontiers in Oncology
, 7
, Article 47. 10.3389/fonc.2017.00047.
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Carmona Echeverria, LM;
Haider, A;
Freeman, A;
Stopka-Farooqui, U;
Rosenfeld, A;
Simpson, BS;
Hu, Y;
... Whitaker, HC; + view all
(2020)
A critical evaluation of visual proportion of Gleason 4 and maximum cancer core length quantified by histopathologists.
Scientific Reports
, 10
, Article 17177. 10.1038/s41598-020-73524-z.
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Fiard, G;
Stavrinides, V;
Chambers, ES;
Heavey, S;
Freeman, A;
Ball, R;
Akbar, AN;
(2021)
Cellular senescence as a possible link between prostate diseases of the ageing male.
Nature Reviews Urology
, 18
pp. 597-610.
10.1038/s41585-021-00496-8.
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Heavey, S;
(2014)
Strategic Targeting Of The PI3k–NFκB Axis In Cisplatin-resistant NSCLC.
Cancer Biology and Therapy
, 15
(10)
pp. 1367-1377.
10.4161/cbt.29841.
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Heavey, S;
Costa, H;
Pye, H;
Burt, EC;
Jenkinson, S;
Lewis, G-R;
Bosshard-Carter, L;
... Whitaker, HC; + view all
(2019)
PEOPLE: PatiEnt prOstate samPLes for rEsearch, a tissue collection pathway utilizing MRI data to target tumor and benign tissue in fresh radical prostatectomy specimens.
Prostate
, 79
(7)
pp. 768-777.
10.1002/pros.23782.
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Heavey, S;
Cuffe, S;
Finn, S;
Young, V;
Ryan, R;
Nicholson, S;
Leonard, N;
... Gately, K; + view all
(2016)
In pursuit of synergy: An investigation of the PI3K/mTOR/MEK co-targeted inhibition strategy in NSCLC.
Oncotarget
, 7
(48)
pp. 79526-79543.
10.18632/oncotarget.12755.
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Heavey, S;
Dowling, P;
Moore, G;
Barr, MP;
Kelly, N;
Maher, SG;
Cuffe, S;
... Gately, K; + view all
(2018)
Development and characterisation of a panel of phosphatidylinositide 3-kinase - mammalian target of rapamycin inhibitor resistant lung cancer cell lines.
Sci Rep
, 8
(1)
, Article 1652. 10.1038/s41598-018-19688-1.
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Heavey, S;
Haider, A;
Sridhar, A;
Pye, H;
Shaw, G;
Freeman, A;
Whitaker, H;
(2019)
Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking.
Journal of Visualized Experiments
(152)
, Article e60216. 10.3791/60216.
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Huang, J;
Huang, D;
Ruan, X;
Huang, J;
Xu, D;
Heavey, S;
Olivier, J;
(2022)
Association between cannabis use with urological cancers: A population-based cohort study and a mendelian randomization study in the UK biobank.
Cancer Medicine
10.1002/cam4.5132.
(In press).
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Johnston, EW;
Bonet-Carne, E;
Ferizi, U;
Yvernault, B;
Pye, H;
Patel, D;
Clemente, J;
... Punwani, S; + view all
(2019)
VERDICT MRI for Prostate Cancer: Intracellular Volume Fraction versus Apparent Diffusion Coefficient.
Radiology
, 291
(2)
pp. 391-397.
10.1148/radiol.2019181749.
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Johnston, EW;
Pye, H;
Bonet Carne, E;
Panagiotaki, E;
Patel, D;
Galazi, M;
Heavey, S;
... Punwani, S; + view all
(2016)
INNOVATE: A prospective cohort study combining serum and urinary biomarkers with novel diffusion-weighted magnetic resonance imaging for the prediction and characterization of prostate cancer.
BMC Cancer
, 16
(816)
10.1186/s12885-016-2856-2.
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Li, Dengxiong;
Shao, Fanglin;
Yu, Qingxin;
Wu, Ruicheng;
Tuo, Zhouting;
Wang, Jie;
Ye, Luxia;
... Feng, Dechao; + view all
(2024)
The complex interplay of tumor-infiltrating
cells in driving therapeutic resistance
pathways.
Cell Communication and Signaling (CCS)
, 22
, Article 405. 10.1186/s12964-024-01776-7.
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Li, Dengxiong;
Yu, Qingxin;
Wu, Ruicheng;
Tuo, Zhouting;
Wang, Jie;
Ye, Luxia;
Shao, Fanglin;
... Feng, Dechao; + view all
(2024)
Interactions between oxidative stress and senescence in cancer: Mechanisms, therapeutic implications, and future perspectives.
Redox Biology
, 73
, Article 103208. 10.1016/j.redox.2024.103208.
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Li, L;
Hobson, L;
Perry, L;
Clark, B;
Heavey, S;
Haider, A;
Sridhar, A;
... Ladomery, M; + view all
(2020)
Targeting the ERG oncogene with splice-switching oligonucleotides as a novel therapeutic strategy in prostate cancer.
British Journal of Cancer
, 123
pp. 1024-1032.
10.1038/s41416-020-0951-2.
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Luszczak, S;
Kumar, C;
Sathyadevan, VK;
Simpson, BS;
Gately, KA;
Whitaker, HC;
Heavey, S;
(2020)
PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer.
Signal Transduction and Targeted Therap
, 5
(1)
, Article 7. 10.1038/s41392-020-0109-y.
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Luszczak, S;
Simpson, BS;
Stopka-Farooqui, U;
Sathyadevan, VK;
Echeverria, LMC;
Kumar, C;
Costa, H;
... Heavey, S; + view all
(2020)
Author Correction: Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer.
[Corrigendum].
Scientific Reports
, 10
, Article 19870. 10.1038/s41598-020-76679-x.
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Luszczak, S;
Simpson, BS;
Stopka-Farooqui, U;
Sathyadevan, VK;
Echeverria, LMC;
Kumar, C;
Costa, H;
... Heavey, S; + view all
(2020)
Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer.
Scientific Reports
, 10
, Article 14380. 10.1038/s41598-020-71263-9.
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Luxton, HJ;
Simpson, BS;
Mills, IG;
Brindle, NR;
Ahmed, Z;
Stavrinides, V;
Heavey, S;
... Whitaker, HC; + view all
(2019)
The Oncogene Metadherin Interacts with the Known Splicing Proteins YTHDC1, Sam68 and T-STAR and Plays a Novel Role in Alternative mRNA Splicing.
Cancers
, 11
(9)
, Article 1233. 10.3390/cancers11091233.
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Lynam-Lennon, N;
Heavey, S;
Sommerville, G;
Bibby, BA;
Ffrench, B;
Quinn, J;
Gasch, C;
... Maher, SG; + view all
(2017)
MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype.
Oncotarget
, 8
(7)
pp. 11400-11413.
10.18632/oncotarget.13940.
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Malone, T;
Schӓfer, L;
Simon, N;
Heavey, S;
Cuffe, S;
Finn, S;
Moore, G;
(2020)
Current perspectives on targeting PIM kinases to overcome mechanisms of drug resistance and immune evasion in cancer.
Pharmacology & Therapeutics
, 207
, Article 107454. 10.1016/j.pharmthera.2019.107454.
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Moore, G;
Lightner, C;
Elbai, S;
Brady, L;
Nicholson, S;
Ryan, R;
O'Sullivan, KE;
... Gately, K; + view all
(2021)
Co-Targeting PIM Kinase and PI3K/mTOR in NSCLC.
Cancers
, 13
(9)
, Article 2139. 10.3390/cancers13092139.
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Morote, Juan;
Pye, Hayley;
Campistol, Miriam;
Celma, Anna;
Regis, Lucas;
Semidey, Maria;
de Torres, Ines;
... Emberton, Mark; + view all
(2023)
Accurate diagnosis of prostate cancer by combining Proclarix with magnetic resonance imaging.
BJU International
, 132
(2)
pp. 188-195.
10.1111/bju.15998.
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Nolan, GS;
Smith, OJ;
Heavey, S;
Jell, G;
Mosahebi, A;
(2021)
Histological analysis of fat grafting with platelet-rich plasma for diabetic foot ulcers—A randomised controlled trial.
International Wound Journal
10.1111/iwj.13640.
(In press).
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Olivier, J;
Stavrinides, V;
Kay, J;
Freeman, A;
Pye, H;
Ahmed, Z;
Carmona Echeverria, L;
... Whitaker, HC; + view all
(2018)
Immunohistochemical biomarker validation in highly selective needle biopsy microarrays derived from mpMRI‐characterized prostates.
The Prostate
, 78
(16)
pp. 1229-1237.
10.1002/pros.23698.
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Pedersen, Katarina;
Vanhoestenberghe, Anne;
Heavey, Susan;
(2022)
Urgent action is required to increase sustainability in in vitro modelling.
In vitro models
, 1
(2)
pp. 115-117.
10.1007/s44164-022-00011-2.
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Pierantoni, Lara;
Reis, Rui L;
Silva-Correia, Joana;
Oliveira, Joaquim M;
Heavey, Susan;
(2023)
Spatial -omics technologies: the new enterprise in 3D breast cancer models.
Trends in Biotechnology
, 41
(12)
p. 1488.
10.1016/j.tibtech.2023.07.003.
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Pye, H;
Singh, S;
Norris, JM;
Carmona Echeverria, LM;
Stavrinides, V;
Grey, A;
Dinneen, E;
... Whitaker, HC; + view all
(2021)
Evaluation of PSA and PSA Density in a Multiparametric Magnetic Resonance Imaging-Directed Diagnostic Pathway for Suspected Prostate Cancer: The INNOVATE Trial.
Cancers
, 13
(8)
, Article 1985. 10.3390/cancers13081985.
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Ryan, S-L;
Beard, S;
Barr, MP;
Umezawa, K;
Heavey, S;
Godwin, P;
Gray, SG;
... Baird, A-M; + view all
(2019)
Targeting NF-κB-Mediated Inflammatory Pathways in Cisplatin-Resistant NSCLC.
Lung Cancer
, 135
pp. 217-227.
10.1016/j.lungcan.2019.07.006.
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Scott, E;
Archer Goode, E;
Garnham, R;
Hodgson, K;
Orozco-Moreno, M;
Turner, H;
Livermore, K;
... Munkley, J; + view all
(2023)
ST6GAL1-mediated aberrant sialylation promotes prostate cancer progression.
The Journal of Pathology
10.1002/path.6152.
(In press).
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Simpson, BS;
Camacho, N;
Luxton, HJ;
Pye, H;
Finn, R;
Heavey, S;
Pitt, J;
... Whitaker, HC; + view all
(2020)
Genetic alterations in the 3q26.31-32 locus confer an aggressive prostate cancer phenotype.
Communications Biology
, 3
(1)
, Article 440. 10.1038/s42003-020-01175-x.
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Singh, Saurabh;
Rogers, Harriet;
Kanber, Baris;
Clemente, Joey;
Pye, Hayley;
Johnston, Edward W;
Parry, Tom;
... Punwani, Shonit; + view all
(2022)
Avoiding Unnecessary Biopsy after Multiparametric Prostate MRI with VERDICT Analysis: The INNOVATE Study.
Radiology
, 305
(3)
pp. 623-630.
10.1148/radiol.212536.
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Sullivan, R;
Heavey, S;
Graham, DG;
Wellman, R;
Khan, S;
Thrumurthy, S;
Simpson, BS;
... Lovat, LB; + view all
(2020)
An optimised saliva collection method to produce high-yield, high-quality RNA for translational research.
PLOS ONE
, 15
(3)
, Article e0229791. 10.1371/journal.pone.0229791.
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Book chapter
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Heavey, Susan;
O'Byrne, Ken;
Gately, Kathy;
(2013)
Targeted Therapies in Non-Small Cell Lung Cancer.
In: Gately, K, (ed.)
Lung Cancer: A Comprehensive Overview.
(pp. 143-172).
Nova Science Publishers: New York (NY), USA.
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Proceedings paper
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Syer, Tom;
Dikaios, N;
Parry, T;
Brembilla, G;
Brizmohun, M;
Singh, Saurabh;
Heavey, S;
... Punwani, S; + view all
(2023)
The Importance Of Multi-Reader Assessment For External Validation Of Prostate Lesion Classification Models Using Quantitative MpMRI.
In:
Proceedings of the 2023 ISMRM & ISMRT Annual Meeting & Exhibition.
(pp. p. 1657).
ISMRM: Toronto, Canada.
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Conference item
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Bailey, C;
Bourne, RM;
Siow, B;
Johnston, EW;
Pye, H;
Heavey, S;
Mertzanidou, T;
... Panagiotaki, E; + view all
(2017)
Validation of VERDICT MRI using fresh and fixed prostate specimens with aligned histological slices.
Presented at: 25th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISRM 2017), Honolulu, HI, USA.
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Brizmohun, M;
Johnston, E;
Latifoltojar, A;
O'Callaghan, J;
Bonet-Carne, E;
Ferizi, U;
Yvernault, B;
... Punwani, S; + view all
(2018)
The intracellular component of VERDICT (Vascular, Extracellular, and Restricted Diffusion for Cytometry in Tumors) MRI distinguishes Gleason 4 pattern better than Apparent Diffusion Coefficient.
Presented at: Joint Annual Meeting ISMRM-ESMRMB 2018, Paris Expo Porte de Versailles, Paris, France.
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Digital scholarly resource
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Heavey, S;
Whitaker, HC;
(2017)
Prostate cancer biomarkers - PSA: is there still a role?
[Digital scholarly resource].
https://doi.org/10.18591/BJUIK.0153
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