Browse by UCL people
Group by: Type | Date
Number of items: 17.
Article
Abouward, Reem;
Abdelhafid, Alya Masoud;
Wilkins, Oscar G;
Lee, Song-Yi;
Ibrahim, Fairouz;
Skehel, Mark;
Ting, Alice;
... Schiavo, Giampietro; + view all
(2026)
LAMP1 and LAMP2A localise to axonal organelles with distinct motility dynamics and partially overlapping molecular signatures in human neurons.
Journal of Cell Science
, Article jcs.264466. 10.1242/jcs.264466.
(In press).
|
 |
|
Birsa, N;
Bentham, MP;
Fratta, P;
(2020)
Cytoplasmic functions of TDP-43 and FUS and their role in ALS.
Seminars in Cell & Developmental Biology
, 99
pp. 193-201.
10.1016/j.semcdb.2019.05.023.
|
|
Birsa, N;
Norkett, R;
Wauer, T;
Mevissen, TE;
Wu, HC;
Foltynie, T;
Bhatia, K;
... Kittler, JT; + view all
(2014)
Lysine 27 Ubiquitination of the Mitochondrial Transport Protein Miro Is Dependent on Serine 65 of the Parkin Ubiquitin Ligase.
J Biol Chem
, 289
(21)
pp. 14569-14582.
10.1074/jbc.M114.563031.
|
|
|
Birsa, N;
Ule, AM;
Garone, MG;
Tsang, B;
Mattedi, F;
Chong, PA;
Humphrey, J;
... Fratta, P; + view all
(2021)
FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation.
Science Advances
, 7
(30)
, Article eabf8660. 10.1126/sciadv.abf8660.
|
 |
|
Bryce-Smith, Sam;
Brown, Anna-Leigh;
Chien, Max ZYJ;
Dattilo, Dario;
Mehta, Puja R;
Mattedi, Francesca;
Barattucci, Simone;
... Fratta, Pietro; + view all
(2025)
TDP-43 loss induces cryptic polyadenylation in ALS/FTD.
Nature Neuroscience
10.1038/s41593-025-02050-w.
(In press).
|
|
|
Covill-Cooke, C;
Howden, JH;
Birsa, N;
Kittler, JT;
(2018)
Ubiquitination at the mitochondria in neuronal health and disease.
Neurochemistry International
, 117
pp. 55-64.
10.1016/j.neuint.2017.07.003.
|
|
|
Covill-Cooke, C;
Toncheva, VS;
Drew, J;
Birsa, N;
López-Doménech, G;
Kittler, JT;
(2020)
Peroxisomal fission is modulated by the mitochondrial Rho-GTPases, Miro1 and Miro2.
EMBO Reports
, Article e49865. 10.15252/embr.201949865.
|
|
|
Fratta, P;
Birsa, N;
Tosolini, A;
Schiavo, G;
(2020)
Travelling Together: A Unifying Pathomechanism for ALS.
Trends in Neurosciences
, 43
(1)
pp. 1-2.
10.1016/j.tins.2019.10.006.
|
|
Fratta, P;
Sivakumar, P;
Humphrey, J;
Lo, K;
Ricketts, T;
Oliveira, H;
Brito-Armas, JM;
... Acevedo-Arozena, A; + view all
(2018)
Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.
EMBO Journal
, 2018
, Article e98684. 10.15252/embj.201798684.
|
|
|
Humphrey, J;
Birsa, N;
Milioto, C;
McLaughlin, M;
Ule, AM;
Robaldo, D;
Eberle, AB;
... Fratta, P; + view all
(2020)
FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention.
Nucleic Acids Research
10.1093/nar/gkaa410.
(In press).
|
|
|
Jarvis, S;
Birsa, N;
Secrier, M;
Fratta, P;
Plagnol, V;
(2020)
A Comparison of Low Read Depth QuantSeq 3 ' Sequencing to Total RNA-Seq in FUS Mutant Mice.
Frontiers in Genetics
, 11
, Article 562445. 10.3389/fgene.2020.562445.
|
|
|
López-Doménech, G;
Covill-Cooke, C;
Ivankovic, D;
Halff, EF;
Sheehan, DF;
Norkett, R;
Birsa, N;
(2018)
Miro proteins coordinate microtubule- and actin-dependent mitochondrial transport and distribution.
The EMBO Journal
, Article e96380. 10.15252/embj.201696380.
|
|
|
López-Doménech, G;
Howden, JH;
Covill-Cooke, C;
Morfill, C;
Patel, JV;
Bürli, R;
Crowther, D;
... Kittler, JT; + view all
(2021)
Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response.
The EMBO Journal
, Article e100715. 10.15252/embj.2018100715.
|
|
|
Moens, TG;
Niccoli, T;
Wilson, KM;
Atilano, ML;
Birsa, N;
Gittings, LM;
Holbling, BV;
... Isaacs, AM; + view all
(2019)
C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A.
Acta Neuropathologica
10.1007/s00401-018-1946-4.
(In press).
|
|
|
Norkett, R;
Modi, S;
Birsa, N;
Atkin, TA;
Ivankovic, D;
Pathania, M;
Trossbach, SV;
... Kittler, JT; + view all
(2016)
DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites.
Journal of Biological Chemistry
, 291
(2)
pp. 613-629.
10.1074/jbc.M115.699447.
|
|
|
Sivakumar, P;
De Giorgio, F;
Ule, AM;
Neeves, J;
Nair, RR;
Bentham, M;
Birsa, N;
... Fratta, P; + view all
(2018)
TDP-43 mutations increase HNRNP A1-7B through gain of splicing function.
[Letter].
Brain
, 141
(12)
e83.
10.1093/brain/awy260.
|
Thesis
|
Birsa, N;
(2015)
Mitochondrial transport regulation in Parkinson’s disease.
Doctoral thesis , UCL (University College London).
|
|
