Browse by UCL people
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Number of items: 31.
Article
Abbosh, Christopher;
Frankell, Alexander M;
Harrison, Thomas;
Kisistok, Judit;
Garnett, Aaron;
Johnson, Laura;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2023)
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Nature
, 616
(7957)
pp. 553-562.
10.1038/s41586-023-05776-4.
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Abbosh, C;
Birkbak, NJ;
Wilson, GA;
Jamal-Hanjani, M;
Constantin, T;
Salari, R;
Le Quesne, J;
... Dessimoz, C; + view all
(2017)
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
Nature
, 545
pp. 446-451.
10.1038/nature22364.
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AbdulJabbar, K;
Raza, SEA;
Rosenthal, R;
Jamal-Hanjani, M;
Veeriah, S;
Akarca, A;
Lund, T;
... Yuan, Y; + view all
(2020)
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma.
Nature Medicine
, 26
pp. 1054-1062.
10.1038/s41591-020-0900-x.
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Agbamu, DA;
Day, N;
Walsh, CJ;
Hendrickse, CW;
Langman, G;
Pallan, A;
Lowe, A;
... Lees, N; + view all
(2012)
Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: The pilot phase of a randomised controlled trial.
The Lancet Oncology
, 13
(11)
1152 - 1160.
10.1016/S1470-2045(12)70348-0.
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Al Bakir, Maise;
Huebner, Ariana;
Martínez-Ruiz, Carlos;
Grigoriadis, Kristiana;
Watkins, Thomas BK;
Pich, Oriol;
Moore, David A;
... Swanton, Charles; + view all
(2023)
The evolution of non-small cell lung cancer metastases in TRACERx.
Nature
10.1038/s41586-023-05729-x.
(In press).
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Bentham, R;
Litchfield, K;
Watkins, TBK;
Lim, EL;
Rosenthal, R;
Martinez-Ruiz, C;
Hiley, CT;
... McGranahan, N; + view all
(2021)
Using DNA sequencing data to quantify T cell fraction and therapy response.
Nature
, 597
pp. 555-560.
10.1038/s41586-021-03894-5.
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Cassoni, A;
Ali, U;
Cave, J;
Edwards, SG;
Ramsay, A;
Miller, RF;
Lee, SM;
(2008)
Remission After Radiotherapy for a Patient With Chemotherapy-Refractory HIV-Associated Primary Effusion Lymphoma.
Journal of Clinical Oncology
, 26
(32)
5297 - 5299.
10.1200/JCO.2008.18.3350.
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Forster, M;
Hackshaw, A;
De Pas, T;
Cobo, M;
Garrido, P;
Summers, Y;
Dingemans, AMC;
... Lee, SM; + view all
(2018)
A phase I study of nintedanib combined with cisplatin/gemcitabine as first-line therapy for advanced squamous non-small cell lung cancer (LUME-Lung 3).
Lung Cancer
, 120
pp. 27-33.
10.1016/j.lungcan.2018.03.007.
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Frankell, Alexander M;
Dietzen, Michelle;
Al Bakir, Maise;
Lim, Emilia L;
Karasaki, Takahiro;
Ward, Sophia;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2024)
The evolution of lung cancer and impact of subclonal selection in TRACERx (vol 616, pg 525, 2023).
[Corrigendum].
Nature
, 631
, Article E15. 10.1038/s41586-024-07738-w.
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Frankell, AM;
Dietzen, M;
Al Bakir, M;
Lim, EL;
Karasaki, T;
Ward, S;
Veeriah, S;
... Gilbert, K; + view all
(2023)
The evolution of lung cancer and impact of subclonal selection in TRACERx.
Nature
, 616
pp. 525-533.
10.1038/s41586-023-05783-5.
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Gupta, RK;
Marks, M;
Edwards, SG;
Smith, K;
Fletcher, K;
Lee, SM;
Ramsay, A;
... Miller, RF; + view all
(2014)
A declining CD4 count and diagnosis of HIV-associated hodgkin Lymphoma: Do prior clinical symptoms and laboratory abnormalities aid diagnosis?
PLoS One
, 9
(2)
, Article e87442. 10.1371/journal.pone.0087442.
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Hobor, S;
Al Bakir, M;
Hiley, CT;
Skrzypski, M;
Frankell, AM;
Bakker, B;
Watkins, TBK;
... Clipson, A; + view all
(2024)
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling.
Nature Communications
, 15
, Article 4871. 10.1038/s41467-024-47606-9.
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Hynds, Robert E;
Huebner, Ariana;
Pearce, David R;
Hil, Mark S;
Akarca, Ayse U;
Moore, David A;
Ward, Sophia;
... Swanton, Charles; + view all
(2024)
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models.
Nature Communications
, 15
, Article 4653. 10.1038/s41467-024-47547-3.
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Jamal-Hanjani, M;
Wilson, GA;
McGranahan, N;
Birkbak, NJ;
Watkins, TBK;
Veeriah, S;
Shafi, S;
... Swanton, C; + view all
(2017)
Tracking the Evolution of Non-Small-Cell Lung Cancer.
New England Journal of Medicine
, 376
(22)
pp. 2109-2121.
10.1056/NEJMoa1616288.
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Jitlal, M;
Khan, I;
Lee, SM;
Hackshaw, A;
(2012)
Stopping clinical trials early for futility: retrospective analysis of several randomised clinical studies.
British Journal of Cancer
, 107
(6)
910 - 917.
10.1038/bjc.2012.344.
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Joshi, K;
Robert de Massy, M;
Ismail, M;
Reading, JL;
Uddin, I;
Woolston, A;
Hatipoglu, E;
... Chain, B; + view all
(2019)
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Nature Medicine
, 25
pp. 1549-1559.
10.1038/s41591-019-0592-2.
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Khan, I;
Morris, S;
Hackshaw, A;
Lee, SM;
(2015)
Cost-effectiveness of first-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy.
BMJ Open
, 5
(7)
, Article e006733. 10.1136/bmjopen-2014-006733.
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Lee, Lennard YW;
Tilby, Michael;
Starkey, Thomas;
Ionescu, Maria C;
Burnett, Alex;
Hattersley, Rosie;
Khan, Sam;
... Johnson, Peter; + view all
(2023)
Association of SARS-CoV-2 Spike Protein Antibody Vaccine Response With Infection Severity in Patients With Cancer:
A National COVID Cancer Cross-sectional Evaluation.
JAMA Oncology
, 9
(2)
pp. 188-196.
10.1001/jamaoncol.2022.5974.
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Lee, Siow Ming;
Hewish, Madeleine;
Ahmed, Samreen;
Papadatos-Pastos, Dionysis;
Karapanagiotou, Eleni;
Blackhall, Fiona;
Ford, Amy;
... Hackshaw, Allan; + view all
(2025)
Hydroxychloroquine in combination with platinum doublet chemotherapy as first-line treatment for extensive-stage small cell lung cancer (Study 15): A randomised phase II multicentre trial.
European Journal of Cancer
, 215
, Article 115162. 10.1016/j.ejca.2024.115162.
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Lee, LYW;
Cazier, J-B;
Starkey, T;
Briggs, SEW;
Arnold, R;
Bisht, V;
Booth, S;
... UK Coronavirus Cancer Monitoring Project Team; + view all
(2020)
COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study.
The Lancet Oncology
, 21
(10)
pp. 1309-1316.
10.1016/S1470-2045(20)30442-3.
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Lee, SM;
Falzon, M;
Blackhall, F;
Spicer, J;
Nicolson, M;
Chaudhuri, A;
Middleton, G;
... Hackshaw, A; + view all
(2016)
Randomized Prospective Biomarker Trial of ERCC1 for Comparing Platinum and Nonplatinum Therapy in Advanced Non-Small-Cell Lung Cancer: ERCC1 Trial (ET).
Journal of Clinical Oncology
, 35
(4)
pp. 402-411.
10.1200/JCO.2016.68.1841.
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Lee, SM;
Hackshaw, A;
(2013)
A potential new enriching trial design for selecting non-small-cell lung cancer patients with no predictive biomarker for trials based on both histology and early tumor response: further analysis of a thalidomide trial.
Cancer Medicine
, 2
(3)
360 -366.
10.1002/cam4.74.
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Lee, SM;
Upadhyay, S;
Lewanski, C;
Falk, S;
Skailes, G;
Woll, PJ;
Hatton, M;
... Hackshaw, A; + view all
(2019)
The clinical role of VeriStrat testing in patients with advanced non-small cell lung cancer considered unfit for first-line platinum-based chemotherapy.
European Journal of Cancer
, 120
pp. 86-96.
10.1016/j.ejca.2019.07.025.
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Litchfield, K;
Stanislaw, S;
Spain, L;
Gallegos, LL;
Rowan, A;
Schnidrig, D;
Rosenbaum, H;
... Turajlic, S; + view all
(2020)
Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue.
Cell Reports
, 31
(5)
p. 107550.
10.1016/j.celrep.2020.107550.
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López, S;
Lim, EL;
Horswell, S;
Haase, K;
Huebner, A;
Dietzen, M;
Mourikis, TP;
... McGranahan, N; + view all
(2020)
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
Nature Genetics
, 52
(3)
pp. 283-293.
10.1038/s41588-020-0584-7.
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McGranahan, N;
Rosenthal, R;
Hiley, CT;
Rowan, AJ;
Watkins, TBK;
Wilson, GA;
Birkbak, NJ;
... Swanton, C; + view all
(2017)
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.
Cell
10.1016/j.cell.2017.10.001.
(In press).
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Moore, DA;
Benafif, S;
Poskitt, B;
Argue, S;
Lee, SM;
Ahmad, T;
Papadatos-Pastos, D;
... Forster, MD; + view all
(2021)
Optimising fusion detection through sequential DNA and RNA molecular profiling of non-small cell lung cancer.
Lung Cancer
, 161
pp. 55-59.
10.1016/j.lungcan.2021.08.008.
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Rosenthal, R;
Cadieux, EL;
Salgado, R;
Bakir, MA;
Moore, DA;
Hiley, CT;
Lund, T;
... TRACERx consortium; + view all
(2019)
Neoantigen-directed immune escape in lung cancer evolution.
Nature
10.1038/s41586-019-1032-7.
(In press).
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Starkey, Thomas;
Ionescu, Maria;
Tilby, Michael;
Little, Martin W;
Burke, Emma;
Fittall, Matthew;
Khan, Sam R;
... NCRI, Consumer Forum; + view all
(2023)
A population-scale temporal case-control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP).
Scientific Reports
, 13
(1)
, Article 11327. 10.1038/s41598-023-36990-9.
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Vargas, FA;
Furness, AJS;
Litchfield, K;
Joshi, K;
Rosenthal, R;
Ghorani, E;
Solomon, I;
... Quezada, SA; + view all
(2018)
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.
Cancer Cell
, 33
(4)
pp. 649-663.
10.1016/j.ccell.2018.02.010.
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Vargas, FA;
Furness, AJS;
Solomon, I;
Joshi, K;
Mekkaoui, L;
Lesko, MH;
Rota, EM;
... Quezada, SA; + view all
(2017)
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.
Immunity
, 46
(4)
pp. 577-586.
10.1016/j.immuni.2017.03.013.
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