UCL Discovery
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Number of items: 17.

Article

Apps, John R; Gonzalez-Meljem, Jose Mario; Guiho, Romain; Pickles, Jessica C; Prince, Eric; Schwalbe, Edward; Joshi, Nikhil; ... Martinez-Barbera, Juan Pedro; + view all (2024) Recurrent adamantinomatous craniopharyngiomas show MAPK pathway activation, clonal evolution and rare TP53-loss-mediated malignant progression. Acta Neuropathologica Communications , 12 , Article 127. 10.1186/s40478-024-01838-4. Green open access
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Chadda, KR; Holland, K; Scoffings, D; Dean, A; Pickles, JC; Behjati, S; Jacques, TS; ... Genomics England Research Consortium, .; + view all (2021) A rare case of paediatric astroblastoma with concomitant MN1-GTSE1 and EWSR1-PATZ1 gene fusions altering management. Neuropathology and Applied Neurobiology 10.1111/nan.12701. (In press). Green open access
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Clarke, M; Mackay, A; Ismer, B; Pickles, JC; Tatevossian, RG; Newman, S; Bale, TA; ... Jones, C; + view all (2020) Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes. Cancer Discovery , 10 (7) pp. 942-963. 10.1158/2159-8290.CD-19-1030. Green open access
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Desaulniers, Daniel; Cummings-Lorbetskie, Cathy; Leingartner, Karen; Meier, Matthew J; Pickles, Jessica C; Yauk, Carole L; (2023) DNA methylation changes from primary cultures through senescence-bypass in Syrian hamster fetal cells initially exposed to benzo[a]pyrene. Toxicology , 487 , Article 153451. 10.1016/j.tox.2023.153451. Green open access
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Grabovska, Y; Mackay, A; O'Hare, P; Crosier, S; Finetti, M; Schwalbe, EC; Pickles, JC; ... Williamson, D; + view all (2020) Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity. Nature Communications , 11 , Article 4324. 10.1038/s41467-020-18070-y. Green open access
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Kirkman, MA; Pickles, JC; Fairchild, AR; Avery, A; Pietsch, T; Jacques, TS; Aquilina, K; (2018) Early Wound Site Seeding in a Patient with Central Nervous System High-Grade Neuroepithelial Tumor with BCOR Alteration. World Neurosurgery , 116 pp. 279-284. 10.1016/j.wneu.2018.05.158. Green open access
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Lechner, M; Takahashi, Y; Turri-Zanoni, M; Liu, J; Counsell, N; Hermsen, M; Kaur, RP; ... Hanna, EY; + view all (2022) Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma. European Journal of Cancer , 162 pp. 221-236. 10.1016/j.ejca.2021.09.046. Green open access
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Li, Y-F; Scerif, F; Picker, SR; Stone, TJ; Pickles, JC; Moulding, DA; Avery, A; ... Jacques, TS; + view all (2021) Identifying cellular signalling molecules in developmental disorders of the brain: Evidence from focal cortical dysplasia and tuberous sclerosis. Neuropathology and Applied Neurobiology , 47 (6) pp. 781-795. 10.1111/nan.12715. Green open access
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Pickles, JC; Mankad, K; Aizpurua, M; Paine, SM; Bridges, LR; Carceller, F; Szychot, E; ... Jacques, TS; + view all (2021) A case series of Diffuse Glioneuronal Tumours with Oligodendroglioma-like features and Nuclear Clusters (DGONC). Neuropathology and Applied Neurobiology , 47 (3) pp. 464-467. 10.1111/nan.12680. Green open access
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Pickles, JC; Fairchild, AR; Stone, TJ; Brownlee, L; Merve, A; Yasin, SA; Avery, A; ... Jacques, TS; + view all (2020) DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study. The Lancet Child & Adolescent Health , 4 (2) pp. 121-130. 10.1016/S2352-4642(19)30342-6. Green open access
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Pickles, JC; Hawkins, C; Pietsch, T; Jacques, TS; (2018) CNS embryonal tumours: WHO 2016 and beyond. Neuropathology and Applied Neurobiology , 44 (2) pp. 151-162. 10.1111/nan.12443. Green open access
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Pickles, JC; Pant, K; McGinty, LA; Yasaei, H; Roberts, T; Scott, AD; Newbold, RF; (2016) A mechanistic evaluation of the Syrian hamster embryo cell transformation assay (pH 6.7) and molecular events leading to senescence bypass in SHE cells. Mutation Research - Genetic Toxicology and Environmental Mutagenesis , 802 pp. 50-58. 10.1016/j.mrgentox.2016.04.002. Green open access
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Pickles, JC; Stone, TJ; Jacques, TS; (2020) Methylation-based algorithms for diagnosis: experience from neuro-oncology. The Journal of Pathology , 250 (5) pp. 510-517. 10.1002/path.5397. Green open access
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Stone, Thomas J; Mankad, Kshitij; Tan, AI Peng; Jan, Wajanat; Pickles, Jessica C; Gogou, Maria; Chalker, Jane; ... Jacques, Thomas S; + view all (2023) DNA methylation-based classification of glioneuronal tumours synergises with histology and radiology to refine accurate molecular stratification. Neuropathology and Applied Neurobiology , 49 (2) , Article e12894. 10.1111/nan.12894. Green open access
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Stone, Thomas J; Pickles, Jessica C; Ogunbiyi, Olumide; Yasin, Shireena A; Taylor, Catherine A; Ahmed, Saira W; Chalker, Jane; ... Jacques, Thomas S; + view all (2025) The tumour microenvironment of pilocytic astrocytoma evolves over time via enrichment for microglia. Acta Neuropathologica Communications , 13 , Article 30. 10.1186/s40478-024-01922-9. Green open access
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von Hoff, K; Haberler, C; Schmitt-Hoffner, F; Schepke, E; de Rojas, T; Jacobs, S; Zapotocky, M; ... Kool, M; + view all (2021) Therapeutic implications of improved molecular diagnostics for rare CNS-embryonal tumor entities: results of an international, retrospective study. Neuro-Oncology , 23 (9) pp. 1597-1611. 10.1093/neuonc/noab136. Green open access
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Conference item

Apps, John R; Gonzalez-Meljem, Mario; Guiho, Romain; Pickles, Jessica C; Prince, Eric; Schwalbe, Edward; Joshi, Nikhil; ... Martinez-Barbera, Juan Pedro; + view all (2024) MAPK pathway activation, clonal evolution, including rare TP53 loss, and the immune environment of recurrent craniopharyngioma. Presented at: 2024 International Symposium on Pediatric Neuro-Oncology (ISPNO), Philadelphia, PA, USA. Green open access
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This list was generated on Sun Jan 11 04:13:07 2026 GMT.