Pickles, JC;
Mankad, K;
Aizpurua, M;
Paine, SM;
Bridges, LR;
Carceller, F;
Szychot, E;
... Jacques, TS; + view all
(2021)
A case series of Diffuse Glioneuronal Tumours with Oligodendroglioma-like features and Nuclear Clusters (DGONC).
Neuropathology and Applied Neurobiology
, 47
(3)
pp. 464-467.
10.1111/nan.12680.
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Abstract
We read with interest Deng et al.'s recent manuscript concerning a newly molecularly defined glioneuronal CNS tumour entity, termed diffuse glioneuronal tumour with oligodendroglioma-like features and nuclear clusters (DGONC)(1). DGONCs were identified by a distinctive methylation profile that segregated away from previously recognised molecular groups of CNS tumours. On further review, the authors describe DGONCs as a novel glioneuronal tumour with key neuropathological features including oligodendroglioma-like perinuclear halos and nuclear clusters.
Type: | Article |
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Title: | A case series of Diffuse Glioneuronal Tumours with Oligodendroglioma-like features and Nuclear Clusters (DGONC) |
Location: | England |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1111/nan.12680 |
Publisher version: | http://dx.doi.org/10.1111/nan.12680 |
Language: | English |
Additional information: | Copyright © 2020 The Authors. Neuropathology and Applied Neurobiology published by John Wiley & Sons Ltd on behalf of British Neuropathological Society. This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
Keywords: | DNA methylation classification, brain tumour, glioneuronal tumour, monosomy 14, paediatric |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept |
URI: | https://discovery.ucl.ac.uk/id/eprint/10118286 |
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